skysight-inc/HackerNews huggingface dataset:
Whether or not the benefits of "golden rice" are overstated, I'd really like to see a DIY implementation of that experiment.

Sometimes I see "CRISPR workshops" which go over the basic theory and walk through performing individual steps like amplifying DNA with PCR and preparing it for transfection, but it's still very difficult to actually get a stable targeted mutation.

And having a goal like beta carotene would be a good opportunity to explain how to research the pathway which leads to a certain chemical, and get a plant to express each step along the way.

I get that people are suspicious of GMOs, but I'd actually like to see a simple gene lab in every home. It takes time to perform this sort of experiment, and if the work could be spread out among individuals who all have their own interests/tastes/climates/etc, we might see more progress in the practicum.

Sadly, synthetic biology is hard, and the equipment would probably take more space than a toaster or a blender. But it's a nice pipe dream.
It's been done... operated 1897 to 1953, replaced by auto delivery.

https://en.wikipedia.org/wiki/Pneumatic_tube_mail_in_New_Yor...
>since you’ll probably forget what suffix you used for each service

You can put that in a safe wallet. OneDrive provides that now
Some of the movies mentioned are well over 50 years old though, so copyright is a root cause even if it isn't the root cause.
We should all try to interpret people's intentions as the best possible intentions instead of the worst possible intentions.

I highly doubt it's sremani's intention is to selectively hurt third world people.

I think it's highly likely that sremani instead believes there's some sort of danger in golden rice, and wants to prevent it from contaminating the food supply and the environment. In sremani's view, sremani is saving third world people from that danger.

Instead of calling sremani racist, we'll make more progress by instead giving evidence that there's no danger in golden rice and that it will help people.
Posted on Reddit, which is also an advertising company.
Toolchain integration matters. Just use c++.
Yes, because the debt analogy is strained:

Debt:
* Interest is due on a periodic basis, with consequences if you default such as recovery, court, reposession, bankruptcy.
* You may be asked to pay back the principal on a trigger (e.g. margin call) depending on the contract, or you may have to pay towards it each month (repayment mortgage)

"Tech Debt":
* No pressure to repay
* There is arguably a recurring cost to having bad structure, but this cost varies based on the amount of activity on the codebase. No new features and only security bug fixes = very little interest and no new tech debt. This is unlike regular debt.
* Can't really be measured accurately (like real debt).
* If the company is sold it is not on the books.

So it's sort of like debt, but not exactly.
Yes; I've been using the same address (dmd@3e.org) for 23 years now. I get ~100 spam/day, and GMail manages to catch every single one. I do a 30 second scan through for false positives once a day - typically there's 1 or 2 a week, and they're never something actually important.
How exactly am I supposed to interpret that?
it is not a good analogy, you can't immediately tell that a piece of code is good or bad. If you could tell that in 10 minutes, if you could separate a good coder from bad just like that, tipping would improve coding as well.

Tipping is not about moody strangers, the vast majority of people eating at restaurants are normal people with normal, predictable and reasonably benevolent behaviors. People will tip if the service is at least average. Won't tip when the service or food is bad. What better way is there to tell how your business is doing?

As many others in this thread pointed out, both waiters and customers like tipping. The minority that hates it has various misconceptions about both how it works, what it does to salaries etc read a few very salient replies in this thread.
Jake Lodwick = Cofounder of Vimeo (acquired by IAC), first dev of CollegeHumor (acquired by IAC), and a serial investor.

https://www.crunchbase.com/person/jakob-lodwick
>There was this amazing article in 2010 about "chemical compounds i will not work with". Tetrafluorohydrazine was one of them:

I remember reading that article it was interesting. But it's funny that hydrofluoric acid (HF) was not mentioned since it seems to be incredibly dangerous.

Periodic Videos on Youtube has a new video about hydrofluoric acid. Professor Martyn Poliakoff mentions HF is feared by people working in chemistry. He also said that even a small drop of HF on skin will cause a heart attack (and eat through your skin).

https://www.youtube.com/watch?v=6ZBwluyR2Tc
I never said patents are the only way. Patents are very important for wealth creation and for the innovations that we see today. Not an opinion, but fact based on my knowledge on the history of wealth creation.
"The high severity and acreage fires commonly seen today are driven by more extreme weather and build-up of fuel from our ongoing fire suppression activities."

If you watch this video https://youtu.be/nb2m8KKuwxk , the bright light goes out, and then we immediately see a big arc and explosion to the left. It looks like an electric problem. It turned out that the light was above a geothermal power station, plugged to PG&E grid. Even PG&E itself admitted that they were the cause of the latest Kincade fire, too, besides the fires that burned Paradise and part of Santa Rosa.
Same here. Had to zoom for it to appear.
I don't think that's a very good argument. I'm sure Bill Gates isn't regularly using composting toilets, because he has access to indoor plumbing. That doesn't mean his efforts to produce these types of toilets for the developing world are in bad faith, or shouldn't be used, it just means he has access to an even better solution that isn't feasable for everyone in the world right now. I think it is reasonable to create a product inferior to the one you use every day for people in poor countries, since poor countries often don't have the infrastructure required for the same luxuries you get in most of the western world.
Great! I can't read anything!
> ATMs are secure because banks would lose money if they weren’t

Now that's wishful thinking. Do you know how hard it is to get your money back from fraudulent transactions caused by compromised ATMs (card skimmers etc - the kinda thing Krebs routinely writes about)?

The banks don't lose their money, they lose your money, and good luck proving this in many countries around the world including the US, UK, Europe.
How many orgs do you know that need to grow beyond a single machine let alone an indie developer? This post was from an indie developer not some big corp engineering blog. I don't know what you mean by partitioning, I'm assuming sharding and not partition/splitting of tables, because this approach is not mutually exclusive to that. MySQL and PostgreSQL can scale up very vertical if designed well. 99.99% or even more never need to scale horizontally. Nevertheless, this can be scaled horizontally carefully a bit. You grow your replicas. Your main DB will be your transactional DB. All procedures that are doing inserts/updates/deletes and select will call that DB. All non transactional SELECTS will call the read only replicas and treat those as your analytical. You can easily have something like one main DB, 3-5 read only DB. Add caching, Add queues and you can have a system that can serve 1+ million users daily.
AFAIK, traditional Arabic/Jewish week starts at Sunday
Therefore:
Ahad (Day 1) for Sunday.
Sabbath/Sabt (Day 7) for Saturday.
I don't mind tipping, especially if I feel the server did a good job. (Not even exceptional. Just 'good'.)

But I am a little concerned about 'tip inflation'. I am just now comfortable going over 10% (with it's easy math), and it seems 15% and even 18% are fading quickly into the past. I'm not wild about paying 20% or more as a tip, it feels like I'm being gouged.
Minimal readability
> Browsers still can't justify text properly. Even with hyphenation (which iirc is still a problem in Chrome), the greedy algorithm used for splitting text across lines still results in too much space between words when justified.

You might try:

word-spacing: -0.1ex;

Good justification of text requires that sometimes the spacing between words is a little narrower than normal. Perhaps browsers are unwilling to do this unless you explicitly give them permission. But I wish they could just adopt a good text-flow algorithm like Adobe InDesign had.

But good justification also requires hyphenation. And last I looked, browser support was spotty. It did not work on Chromebooks, for example.
Enable Sidecar on Unsupported iPads and Macs Running iPadOS and macOS Catalina
What kind of student of science are you? to guess my race based on my comment!

Let me be very clear here, I have lived my entire childhood in one of the countries mentioned. Your jumping to conclusion in itself is an evidence that you are unworthy of any response, beyond this one.
This is a false analogy.

You can choose to go to a different restaurant, you can't choose to deal with another government. Hence the rules should be different.

The rules and regulations of a governmental agency do not need to have any bearing on the rules and regulations of a private business.
If we don't do everything we can to help millions of people somewhere in the world, are we racist?

One way to save lives is to actually import people into our homes. We can probably just mandate that everyone reapportion their home such that every 8 feet is another room, and then just start migrating people and moving them into the homes of more fortunate people. From there, if you have enough money to feed them, you will be mandated to do that also. Even if it means lowering the amount of money you allocate to your own family members - so be it. It will save lives.
Agreed, and they're having to use extensive analogies just to communicate the concept in a coherent way. If it was simple then you would think it could just be explained as it is in itself.
I deeply agree, but dynamic scheduling can have a strong negative affect of causing you to always stay in "work-mode". If I spend my mornings doing errands, cooking, or hitting the gym, I may end up working well into the evening up to the point just before I fall asleep. Or more likely, I shave hours from my "work-week" working about 6 hours a day, and find myself working throughout the weekend without any "mental rest".

I think humans have always struggled with finding ways to be happy in whatever circumstances they are provided, and remote work and the new global economy are going to force us (through some struggle) to figure out the best ways for ourselves to get on.

Ultimately as I mention in my original post it's about self-discipline and structure to do what you know will make you happy, but strangely that can be pretty hard.
> it's hugely more efficient for a single truck+driver to deliver 100's of packages in a single day than for 100's of individual people to spend an hour each going to/from a store

Not sure if by "efficient" you also mean it's better for the environment, but I did hear from some researcher that deliveries are ecologically much worse than going to the store. The podcast/"lecture"[1] is in Flemish (and audio/video isn't very accessible), so I'll translate the main reasons:

- Many disparate products moved to many individual homes (many to many makes for a lot of 'movements', fragmentation)

- 15-20% of people is not home during a delivery attempt (useless impact)

- Returns are equally bad (people order 8 pairs of shoes knowing they'll send 7 back)

- Different delivery companies cause even more fragmentation (driving to the same home)

Of course, you might just have meant efficiency of trucks as opposed to 2-ton cars occupied by single persons (assuming most people in NYC would do their shopping by car -- as a European, I can't imagine doing that in large cities' centres, but I do hear the USA is very car-oriented so I don't know how it is in NYC).

[1] https://www.youtube.com/watch?v=IRqKEK_xJvc
Also, the "lucky fish" made of iron which, when placed into a cooking pot, prevents iron deficiency in millions of children.
Boost Your Memory and Watch Creativity Blossom
I’ve been reading a sci fi book called the windup girl. The setting is a future where agri-tech companies and bioweapons proliferated until some conflict happened that led to almost all crops on earth being wiped out, and only innovative new produce could survive the engineered diseases, so the agri-tech companies have incredible power since the world depends on them for its survival.

I would like to think it’s unlikely to really happen, but I’ve read news in the last 2 years about the USA researching tech that could lead one day to these types of scenarios[1]. There was also agent orange etc in Vietnam, showing a willingness to use such tech even in less serious wars (eg, compared to ones that endanger your cities).

[1] https://www.sciencedaily.com/releases/2018/10/181009102511.h...
Just pointing out that this is an article from 2017 and was discussed before on hn https://news.ycombinator.com/item?id=15564639
How much is justice worth to you? I think it would be worth it for the police to have squads of people dedicated to this when we spend so much on things like EOD techs, armored cars and SWAT teams in America. Phone thievery should be a risky business to associate with.

Also, the police absolutely have no business caring if something is valuable, their work all pays the same. What you are suggesting is not justice at all, and justice is at the very core of American values.

In your dad’s story, suppose he had a receipt with a serial number, which is fairly common these days. The police absolutely should have done something. The fact that you see activation locked phones on eBay is honestly disgusting, stealing a smartphone should be treated as a special case of grand theft like stolen cars! A $300 asset loss is a big hit for a lot of people, and the impact it has on the victim’s life beyond the monetary loss is substantial and usually lasting(loss of photos, contacts, communication, banking)

Try getting your phone stolen when you just started a vacation or lost a job(or both at the same time like me).
> updated up to twice daily

Far from ‘live’
There are plenty of industries where people invest without a government granted monopoly. If they don't want to invest without this, maybe they shouldn't.

Meanwhile I am under the impression that public funding works better for these sorts of things anyway. So they will pay in their taxes and it will serve the public good.
Great write up. So many hours spent playing this game and trying to figure out how to wring the last bit of himem to get it to run better.
> benefits are too diffuse and too hard to measure.

Wouldn't "the feature gets done in 1 day instead of 2 weeks" be a very specific benefit?
Conflict of interest rules apply the same way to governments (foreign and domestic) as they do to any other company you're considering doing business with. You can't give their representatives gifts either over a handful of dollars, if you've ever watched a compliance training video at work. I'm not using this as an analogy, just as prior art in the restriction of your ability to give arbitrary 'gifts' or 'expressions of gratitude for someone having done their job'. I mean, why can't I tip a police officer who came out really quickly to look into my home invasion? It's my money and I'm not paying them to do anything they shouldn't. I'm just grateful they did their job.

The point remains, you can give anyone gifts in a personal capacity, and there are restrictions in a professional capacity.
Homegrown on private clouds. Rackets have moved from offline security to online security. Large mafias are highly sophisticated tech wise.
The Atlantic article serves as a great reminder of why alternative media picks up more and more steam, and why "fake news" is a problem that isn't just limited to smaller groups.

Let me present an alternative outcome: when the SyGov enters into joint-control of Northern Syria, nothing will change. And the bulk of the SDF will be incorporated into the Syrian military... exactly as the same as what has happened every single time this has happened in the last 8 years.

There is not a single reason to suspect otherwise, and propagandists like Hassan Hassan and co. will just find a new talking point next week.

It's actually ridiculous that the inner-circle of Twitter MENA propagandists, led by Henry Jackson Society notables like Michael Weiss, are still the go-to "experts" people depend on and still have a platform to spread their poison in 2019.
I wonder what this means for StartMail’s (startpage’s email) clients?
The original version of golden rice was even worse - that very definitely didn't have sufficient beta carotine to be effective. Some weird and subtle compatibility issue between the particular gene they used and the way they were trying to get it to be expressed that I'm not sure anyone fully understands. That unfortunately hasn't stopped GMO advocates from accusing opponents of GM foods of causing massive deaths and childhood blindness by blocking the rollout of that first version.
That's true - while I mostly don't buy the 'frankenfood' scare, I worry about the dangers to the ecosystem. For example a GM crop that is fungus/insect resistant, but the resistance is due to a herbicide/pesticide it was engineered to synthesize, that is later found to harm some key species (the way neonicotinoids were found to harm bees). Only recalling it will be much more difficult, especially if the genes spread to other species (such as by horizontal gene transfer). All the while the corporation selling the crop has every incentive to try to hide the ill effects.
Hong Kong Free Press calls for immediate release of freelance photographer
CEOs can get the market very wrong. Boeing developed the 787 to meet a vision of point-to-point long-range flight using smaller aircraft that could fly out of medium-sized airports with high load factors. Airbus bet on hub-and-spoke and developed the A380, which turned out to be a substantial misreading of the future.
So what do you called an unmanned spacecraft? We've got unmanned aerial vehicles (UAVs), and unmanned submersible vehicles (USVs), and and unmanned land vehicles (ULVs), are they "unmanned orbital vehicles" (UOVs?) or maybe unmanned rocket vehicles? (URVs?)
A good step would be to cut down and destroy every eucalyptus tree in CA and make it illegal to harbor the species. It is an invasive species from Australia and should not exist in North America. It has shredding bark which ignites, breaks loose, and flaming embers are carried long distances spreading the fire more quickly than native species.
Here is a couple of specific examples:
https://medium.com/firebase-developers/patterns-for-security...
https://firebase.google.com/docs/firestore/solutions/role-ba...

You do need to have you ACL data also stored in the database, which can be a hassle if you have existing ACL system already built outside of Firebase.

xrd, do you have a specific question about private data in Firestore?
The recommended way off installing it uses apache instead of nginx, which happens not to be vulnerable.

Only if you looked up their instructions for nginx did you get burned.
I looked it up and this was the first result

https://pdfs.semanticscholar.org/c911/5ad056fc1bb4f257fa6109...

http://www.goldenrice.org/PDFs/Dubock-The_present_status_of_...

> "In conclusion, each of the studies discussed regarding the effectiveness of golden rice concluded that it was indeed effective at providing vitamin A. "

Stone and Glover are saying that the current studies which prove Vitamin A are effective aren't comprehensive enough. However as far as I can tell all the research so far points to golden rice being effective.

Stone and Glover later wrote: "IRRI’s own assessment that the rice may augment the already successful nutrition and breastfeeding programs, at least in
some ‘‘difficult to reach’’ areas, is plausible."

Sound like they are critical of it for many reasons but accept it working as a possibility.

https://pages.wustl.edu/files/pages/imce/stone/stone_glover_...
> if there's a fundamental distrust (or even disrespect) of software engineers as domain experts.

Physicians enjoy a similar problem. Everyone goes to Dr. Google an then brings their misunderstandings to the clinic. Anything goes wrong, it couldn't possibly have been the fact that the patient was a brittle diabetic with hypertension. It must be the care they received in the hospital after they had a heart attack while driving and ran into a tree. Nor is anyone else in the hospital possibly making mistakes. Clearly it's the board-certified physician who doesn't know what they're doing.
Looping Music Seamlessly
Huh me too. This is the first time someone else has described this which ive found. I like the analogy to dyslexia.

It amazes me when people say things like "oh in april two years ago such and such". To me thats about the same as saying 25.535E6 seconds ago. Mostly meaningless
It's true that a lot of it happens that way. It's not particularly healthy and has extreme side effects in situations like the one at hand (suddenly moving to full time remote) People should diversify their social life.
Beautiful GIS system.
This should be linked. Much better than the currently linked site.
Jira front end architecture (r)evolution: mistakes, revelations and human nature
Excellent maps, thanks for sharing, commenting so I can find this again.
Keeping the Lights On, and Saving Billions, While Addressing Climate Change
I don't think I've ever run into an issue with a payment gateway. The one major site I've had issues with has been playstation.com. Sony seems to use a bunch of different domains for managing its various PSN websites, and I've never found the right set of rules in uMatrix without also enabling third-party cookies.
Unlikely since we are piping the output of TREE back into TREE, which is much larger than n+1.
great now do chinese

edit: or thai, or arabic
How does tipping a pretty girl become as you say "a tax collected from black, ugly or fat girls"? If you said there is an "unfair" advantage I get that (not that I agree but at least I understand). What I don't get, how is it a tax?

While we are at it, are you saying there should not be jobs where pretty people make more than ugly people?
Lucky Iron Fish
African Swine Fever Will Impact Global Protein Market for Years
but what if those people are already paid well? not that I know, but it is so easy to be an armchair general, that has all kinds of opinions on how to run a restaurant
Reposting my old comment: https://news.ycombinator.com/item?id=7951964

> I don't see why the analogy to debt is necessary when the direct analogy is to capital underinvestment: in fact what we're talking about is or very nearly is just that, capital underinvestment, not simply something analogous to it. And the hypothetical businessy, non-technical types whom the debt analogy is intended to enlighten understand very clearly what deferring capital investment is and what the likely consequences are, at least if they actually know anything much about business.

msandford's reply https://news.ycombinator.com/item?id=7951978 was good:

> Most of the people who are pushing for "features now, someone else's problem later" are probably not upper management but rather middle management. Upper management might understand capital underinvestment. Capital underinvestment is very nearly the sole job middle management is there for. And berating people for not being done yet. At least at a couple of the places I've worked.