skysight-inc/HackerNews huggingface dataset:
Is there any law as to purchasing/producing unregulated drugs in the US? If not, I'm surprised some budding pharmaceutical chemist hasn't swooped in and started producing these sorts of drugs. You know, free market capitalism and all that.
They are generally $0.15-$0.25 without insurance, and only rarely over $0.6, in the U.S. where this took place.
Interesting point about insurance companies saving money that way. I know that some insurance companies are starting to run medical practices and pharmacies, I wonder how far away them making their own drugs is. Unfortunately, I fear that that's the direction of further distopia.
That depends on the time scales we're talking about. 30 years? Probably (and even then there are problems with abandoned/little-documented formats like Word 3.x). 300 years, and a historian will have a hard time decoding a digital file from the year 2019, even assuming the media is still intact. 3000 years and a nuclear war can make a weird shiny disc appear as a currency or a cult item for an archaeologist, not as a knowledge storage.
For search capability you could try the method shown here: http://www.highfivehq.com. Basically you mark the edge of a page in the spot that corresponds to an index. You can then find items form a certain category by looking at the edge of the notebook. It's an interesting concept if you don't need a ton of granularity in your ability to search.
It's worth noting that this isn't about the type of insulin either - the NHS generally prescribes the new, fancy insulin analogues to type 1 diabetics as their first choice because they provide actual clinical benefits, despite this article's claim that they're a giant con that only exists to line the pharmaceutical industry's pockets. In particular, Lantus used to be the recommened long-acting insulin of choice for new patients until they switched to something even newer a few years back.
"Dragon's Egg" pdf: http://investigacion.izt.uam.mx/alva/DragonsEgg.pdf
There is an ongoing project to carve knowledge on clay tablets and seal it in a salt mine in Austria. Sounds like it checks some of your boxes.

https://www.theatlantic.com/technology/archive/2017/01/human...
Sadly it is not about how much manufacturing and research costs.

But about how much they can profit from it.
I miss forums. vBulletin, Invision, phpBB.
"Mistakes"
No.

Learning is very much a multi-sensory process. The act of writing is part of the learning - the two-dimensional shapes your fingers trace actually help cement the memory in your brain. (And no, simply clacking away on the keyboard is not the same.) As these authors [1] say: "the additional context provided by the complex task of writing results in better memory."

[1] https://journals.sagepub.com/doi/pdf/10.1177/154193120905302...
It's unrealistic precisely because it's unpopular and will not get support. It's the same as Sanders proposal. Offer free stuff in exchange for votes knowing that you won't actually get approval for the free stuff.
Do you have any reference for your load balancing and replication algorithms?
There's a guy on YouTube that got me into it which I highly recommend, called 'LOOK MUM NO COMPUTER'. He made a synth organ out of old Furbies toys. From that point I was sold.

Also, as much as I love the Thonk products, don't get put off by the price tags of some of their kits if you're intimidated! Some of my favourite synths have been made from penny parts I got from Alibaba, that totalled about £15 to make. They have a habit of sometimes spontaneously exploding, but that's all part of the fun.
We should be focused on designing "smart systems" that optimize measurable outcomes

Who cares how complex the algorithm is! What matters is that it works better. Is there a measurable outcome that matters? Can the system optimize that outcome over time, through a coordination of human processes and technology design?

That is what organizations need. Not hyperparameters.
Another person commented on a different thread that he was buying some kind of auto-injection pen that fetched a premium to the bottled stuff. It seems he was not aware that he could’ve used the regular bottle stuff and saved a LOT of money.

The pharmacist should’ve given him a better consult and told him options for cheaper stuff. I had a pharmacist and a tech search for 30 mins several times for a rebate that brought my cost to $0. They will suggest another medication if the one you are getting isn’t covered. They will even call you doctors to get a new script.

It seems there were failures on multiple levels. He should’ve been aware of better options. The pharmacist shouldnt have let him leave when he couldn’t afford it.
There are non-statistical methods for training neural nets (no backprop) so 'applied computational statistics' really wouldn't capture it. Beyond that what is wrong with the term deep learning? I can at least understand objections to the use of the term AI (even though it was originally used to refer to narrow AI but was appropriated by hollywood) but deep learning seems like a fine term to me.
While true now, remember that companies used to own armies[1] and territories[2]. Their motives -- shareholder profit -- have not changed. They do and will strive to grow their power.

It's not a stretch from today to imagine living on company-built cities with private security, paying rent and utilities to the company, with contracts and EULAs serving as laws in all but name.

[1] https://en.wikipedia.org/wiki/Dutch_East_India_Company

[2] https://en.wikipedia.org/wiki/Company_rule_in_India
Libra Cheatsheet
I never said I was convinced that the cleanup is easy or even possible - I said we have to start trying it. And I support projects which are at least trying - no matter if they attack the source or the symptom of the problem.

While some people focus on changing policies can and should do impact at the source of the problem, other people focus on engineering solutions for fighting the existing problem. Not everyone can become a policy maker/politician - so please cut those at least trying some slack.
Looks like we need a bit more clarity on what they mean by "glass".

If you look at glass in medieval glass windows it's heavily distorted by gravity (fatter at the bottom than the top) and that's after ~900 years, so presumably they're actually meaning something more robust than that!
Oh it is obvious - in this specific case - but the main issue is that the line between original content and advertisements is blurred. I noticed the same on Facebook - if it's not actual ads, it's my FB friends raving about a movie, a game, a destination (think Disneyworld), a thing they got, etc - so basically most content is ads.

The They Live sunglasses should be an extension that can abstract these things to keywords like "CONSUME" for product promotion and "MARRY & REPRODUCE" for relationship updates / family pictures.
Yes and no...
https://www.snopes.com/fact-check/insulin-walmart-vial/

There are other articles available that describe the situation.

tl;dr - Yes, you can get a vial of insulin for $25. But, it's not the same kind of insulin most diabetics take. They are typically prescribed insulin analogs, which still require a prescription. The $25 version could likely keep them alive, but the dosing/usage/effects are not as consistent.
Headline doesn't match the site, and the article reads largely like Bitfinex PR.

The idea that large, savvy investors with millions to spend are going to put their money into a currency that's already had nearly a billion dollars seized and under investigation by the NY AG is simply not credible to me.
Obviously this is a huge problem. For a more analytical perspective, take a look at Slate Star Codex on drug shortages and price gouging:

https://slatestarcodex.com/2019/04/30/buspirone-shortage-in-...
When I take notes I take them with a laptop precisely because of the increased speed it provides. Usually I find that note taking in general is actually counter productive because it diverts my attention away from the lecture. As a result I want the note taking process to have a low cognitive burden so I don't miss what my instructor is saying.

I usually use Emacs Org-mode for my note taking and then refactor my notes once class is over.
I'm not at all trapped in a media bubble. I simply stated that I support multiple attacks on the very real and existing problem. Every ton of prevented plastic in the water is a net gain. Every ton of removed plastic from the water is a net gain.
> The problem that I see with this approach is that we are privatising profits while socializing costs.

The costs in question are the costs of achieving a government goal. It’s not like FedEx expects the government to pay its shipping bill. But when a government mandate costs FedEx money, it wants to be compensated for complying.
This is not very different from large chunks of European OSS. The language and cultural barriers are real. No need for paranoia.
How do I get one of these? Do I go to my doctor and tell him: Hey, grandfather had Parkinson’s so I want to double-check myself?
But it's a problem they're clearly working on. And as long as these compromise threats are not perfectly dealt with, customers should very much be concerned.
How did you learn. Where should someone start? I think now is the perfect time to learn shorthand since we have abandon hand writing completely due to overusing computer, mobile etc
So any startup that basically provides insurance that covers 10 cents but gives access to insurance pricing for like $10 a month?
dd if=/dev/data | tee >(dd of=/dev/glass1) | dd of=/dev/glass2

20:20 optical replication ;)
Not a chemist but in NL S-A shows 33,50 eur/100g (ships today!)

https://www.sigmaaldrich.com/catalog/product/aldrich/132098?...
Yes, amazing, but can it be played through Chrome, VLC, mpv or more importantly Android and iOS?
I'd prefer that our society classifies it as illegal rather than evil or immoral. We need to have laws which also take away the acquired wealth from those who benefit from such practices.
> From what I understand, the US culture is one in which it is generally considered the fault of someone for being unable to pay for their own healthcare and living circumstances. Because there is the sentiment that it is possible to not be oppressed through one's personal power, cleverness, and considerate behavior, the people who claim to be oppressed are actually lazy, stupid, and inconsiderate.

That is not "US culture". Those are the beliefs of an unfortunately sizeable minority. Even then, it is generally only directed at "the other" and is really veiled racism. Do not take the rhetoric of certain political factions at face value or as a representation of "US culture".
Why is insulin not being sold illegally? Like a black market of imported insulin? Or is it?
I used that same method throughout college. I think I might have read about it somewhere.
update: the £50/MWh and £90/MWh are both commercial bids that will have factored in probability of generation to the best of the bidders ability. the companies making them will fail if they go hugely wrong. (though in the nuclear case taxpayer might be left with cleanup)

You are correct that the non-constant nature of wind means you need to cost in some storage, or transport via the grid (generally it'll be windy someplace or other). But probability of generation is not the issue.
I'm not pro-China in any case, i really believe in liberalism, but i think in history, and with the exception of Tibet (That's not really an exception tbh if you get back in the historical context), China was never known for waging exterior wars. Internal wars however...
I work with a company that imports and exports physical products to the U.S. regularly.

Yes, you could probably get away shipping a dozen phones a few times. But they will catch it eventually. They do actually inspect paperwork and sometimes contents.

And if they find out you've lied on the paperwork, you've earned yourself a shit list that's going to extend to any travel you do to/from the U.S. for life, on top of penalties and possibly arrest warrants.

They don't mess around.

I should add: CBP shares offices at the border with the couriers. They're literally down the hall from each other. They're inspecting packages crossing the border all day long, but it's a random sampling, so whether it's your day or not is a matter of luck. They also have mobile x Ray trucks that scan full semi trailers.
Check out Kaivo (Vst), Prism (for Reaktor) and Chromaphone 2 (Vst). They are not the freshest of the fresh, but certainly interesting.
While I agree with you in the context of making synth sounds, I just wanted to note that physical modelling is amazing for real instruments if done right. For example, take MODO bass - none of the sample based solutions come close.
> C, D, C++, rust, and nim should all have comparable performance

No, Nim is often among the fastests, sometimes surpassing C. This is because it targets C by default and uses data structures and code paths that GCC can optimize very well.
Pen and Paper's killer feature is that, aside from doodling, is distraction free.
It's certainly another tool available to reach people in regions where there are an oppressive dictatorships running media like North Korea.
Some big hospital chains are starting a nonprofit generic drug manufacturer, Civica Rx. This seems like a promising step forward. For those more inclined to direct-action, there's Four Thieves Vinegar [1].

[1] https://fourthievesvinegar.org/
Clearly not, because i do not use social media, and i see no point in instagram either - because those platforms offer nothing of value to my life - other than being a platform for harvesting tons of personal data, so they can sell targeted ads towards you.

On a side note, plaintext site is a pleasure to read, and loads lightning fast - i really recommend it.

Influencers are basically a walking, breathing marketing platforms, that seem more down to earth or intimate than typical ads - basically a human version of targeted advertisement mixed with surreptitious advertising.
What's left out of most conversations around insulin.

- The incidence rate for diabetes has skyrocketed over the past 25 years. It's estimated that 100 million Americans are now living with diabetes or prediabetes.

- Most of the patents for the newer insulins are mostly on manufacturing processes. Read up on Lusduna if you want to see how difficult it is to bring an insulin to market in the US.

- Biosimilars are significantly more costly to bring to market than generic drugs.

- Alex Azar, and every other secretary of HHS have had the ability to allow legal importation of drugs from Canada since 2003. We actively choose not to. While IMO the risks are worth the benefits, I will concede the other side does have a valid argument against importation.

- The price difference is with fast acting insulins. These insulins offer a higher quality of life relative to the older insulins. The clinical benefits of using a fast acting insulin versus something like Novolin 70/30 (aka Walmart insulin) are negligible, while the price difference is substantial. (Talk to your physician before switching insulins) From the people I've talked with, fast acting insulins are a godsend if you have diabetic children or can't keep a regimented schedule.

- All of the companies that manufacture insulin are public and you can read through their financial statements to verify that what they are saying is true.

All that being said...

I'm surprised that an enterprising Canadian has not exploited insulin arbitrage.

You can buy insulin over the counter without a prescription in the USA and Canada. Canadian law does not prohibit exportation of drugs to the United States.

Theoretically you could set up an escrow service that connected Canadians who wanted to make a buck with American diabetics. The service could offer insurance in case a delivery was not made and you needed to buy insulin in the US.

Obviously this would complicate things with your insurance. No insurance company is going to cover bootleg Canadian insulin when it comes to your deductible.
NY Post deletes story of rape allegation against Trump for Trump-loving editor
Just don't get into writing synths or effects if you want to make any money. Kind of like making games, it's flooded with people who do it for the love and willing to do it for salaries far less than other fields. The stereotypical musician has no money. There are currently over 3000 synths listed on KVR. It's tough to do something unique and stand out.
Who SAP? They are not quite as bad as Oracle but in the same league.

Which devil do you want to get locked into?
Maybe the problem is that ever since google the only metric anyone has bothered to devise is "popularity", which was never a particularly good indicator of truth to begin with.
Both? The first of the Three-R's is Reduce. It's always more effective to prevent a problem than to clean up after it, but that certainly doesn't imply something shouldn't be cleaned up...
India ( NCR, Remote )

I am currently working on a product in the News field and looking for someone who is excited about disrupting how people consume news online.

The product is in it's early stage and I am developing it in my free time. I plan to launch within 2-3 months for the Indian Market ( Go global later ).

Email in my profile.
Alexa scientist: How to do fast, accurate multi-category classification
> regular people with kids and families and feelings.

This is just an appeal to emotion. No-one is even calling out any individual people. With a company of this scale and responsibility, individuals shouldn't even come into the discussion, and there should be multiple levels of redundancy. Verizon, collectively, is being shamed.

Verizon should be compared to a power plant, not a SaaS provider or some 3-person dev shop.
This is very impressive! I know the web audio APIs are not new, but this is a very slick user experience. The way the corners of the box move as you drag the controls around - Italian chef finger-kissing gesture
Wait. I am confused. Are the types of posts like in the article considered "stealth advertising" now? Do you people regularly buy a product because someone you follow on instagram uses it?
Scaling a State of the Art Deep Learning Model in Production
Or go virtual modular https://vcvrack.com/Rack.html and keep your house
A No-Loss Lottery
> Most jobs, such as mine,

Most jobs don't give insurance in America
Also keep in mind that messing up an insulin dose can kill you pretty quickly, so I can see why it would be particularly frightening. Not that it’s worse than certain death.
Aww are you a little Butt hurt because somehting didn't go your way and now you're resorting to whinging like a baby on the internet to "get justice"

hahahahahahaa

Gimp
They are legally required to if they fall under FCC jurisdiction.

For entities that fall under the jurisdiction of the Federal Communications Commission (the “FCC”), “[e]ach carrier that offers or bills toll telephone service shall retain for a period of 18 months such records as are necessary to provide . . . billing information . . ..” (47 C.F.R. § 42.6).

https://morningconsult.com/2017/04/25/tech-groups-push-fcc-u...
Scala programming language wins SIGPLAN award
I agree, I was just noticing that such a ridiculous margin should allow for other actors to step in at lower price points. Maybe maire's sister does not have half a mil lying around to kickstart the experiment, but with these numbers, sooner or later someone likely will.
> Why can’t you just take a picture of the diagram?

Because the learning effect is zero. (Also, not every professor allows it, and you don't always sit in a location from which you can take a decent picture. But that's beside the point.)

The best teacher I ever had in school never got tired of reminding us that we learn in four different ways: hearing, writing, speaking, drawing. Taken individually, hearing is the worst, drawing the best. The more you combine, the better your rate of recall will be.

Drawing is fantastic because it engages your kinesthetic learning, your spatial learning, and your analytical learning (because you really have to look at a picture in detail before you can copy it).
The Challenges to Forging a U.S. – China Trade Deal
Still, auto-injection pens are not rocket science. In Sweden, maybe they'd double the cost to $1200/year, though I doubt they'd do that if mass-produced.
Sounds like one. However the DB vendor business is certainly hard to get into and survive. If pingcap has that many paying customers then well done.
Turned out it was a mistaken belief. Basically, thickness invariance in medieval glass had to do with the manufacturing process, and the viscosity of glass is not observable in a human timeline.

https://ceramics.org/ceramic-tech-today/glass-viscosity-calc...
Possibly you aren't aware, but both FP and OOP are orthogonal to mutability. There are lots of mutable FP languages (for example, the first one ;-) ). These days it is popular to make pure FP languages, but that was not the case 40 years or more ago. Similarly, Alan Kay had quite a lot to say about mutability in Smalltalk. I'm not aware of any pure OO languages, but very few people knew how to deal with persistent data structures until Chris Okazaki's PhD thesis on the topic ~1996, if I remember correctly. Mutability is really up to the programmer. Even in C++ you can have const data structures and even const functions -- which are guaranteed to be pure. C++'s mistake was that it didn't make const the default; a mistake that Rust corrected. Back in the 90's all of my C++ code had const strewn all over it -- it was on practically every line. It was really clear to those of us doing it that you had to separate your "const" code from your "non-const" code because if you ever decided to omit that "const", it would rot your entire code base in a very short time frame -- mutability is really contagious.

I know it's popular to hand-wave and say, "Well most OO programmers don't write immutable code and lots of design patterns depend on mutability so therefore OOP is defacto-mutable while FP is defacto immutable", but this really obfuscates the true nature of the issue. There are programmers who prefer to write mutable code (in any paradigm) and those who prefer to write immutable code. It's quite easy to write OO code in an immutable way and most statically typed OOP languages even give you tools to help you do it. The reality is that many programmers just don't care. Of course, those programmers never reach for a pure FP language, but there are still heaps of old school FP programmers who would never write immutable code (I know several personally).

Perhaps you knew all that as well, but if so, I would ask a favour that you don't say "OOP is mutable" because it is highly misleading for people who don't understand the issue well (and frustrating for programmers like me who enjoy writing immutable OO code).
Travel Startup Utrip: A Post-Mortem
Climate apocalypse.

We have approximately 4-5 years left to mobilize massive de-carbonation in order to stave off the worst effects of climate change [0]. It's already too late to avoid 2C warming. Even if we stopped instantly today the feedback loops have been in gear for years.

Small, incremental changes are not what I was hoping for.

[0] https://www.earth.com/news/5-years-mitigate-climate-change/
How to check important warnings given by the PVS-Studio analyzer for C and C++
Combined with a good text compressor you could get > 100 hours of speech on it.
http://www.mattmahoney.net/dc/text.html
Using Sky Segmentation in iOS to create background animations
I might use something like this, I have a few small sites. The cheapest pingdom plan is $15/mo which seems like too much for what I'd need.

How did you determine that there's a market for this? I ask because I'm trying to learn how to validate demand.
With the same amount of training/data as NNs? I doubt it...
The pointless popups became acceptable again because of the pointless cookie law forcing developers to implement dark ui. By the way did you know browsers use a thing called cookies? Scary i know.