skysight-inc/HackerNews huggingface dataset:
For more regulated classes of drug the FDA doesn't just control the conditions under which it is made but also assigns production quotas to different manufacturers. The prime worry, I believe, is that if too much of a controlled substance is produced and it isn't sold then it might end up being sold illegally. There are also issues where allowing people to produce a drug willy-nilly would stretch the FDA's inspection capacity and allow the possibility of defective drugs being made.

Plus there's the issue of whether a drug can remain safe to use after long periods of time at all.
79%... just can't seem to get the last percentage point...
Or maybe they never saw it because it didn't happen in the magnitude or significance that they all must now agree was definitely the case.
Music reviews on Amazon were a dream back in 2008 or so. Far from the pretentious babble on Pitchfork and sites of that ilk, you could get concise, single paragraph reviews from regular people trying to explain what they liked/didn't like on the record.

Those days are long gone, since everybody streams now, and genuine user reviews have dried up. Last.fm was another great site, but it's a ghost town now, and the band comments sections are full of spam.

At least rateyourmusic.com is still chugging along.
Then by your definition I am not a radical-progressive.
I find the problem lies with the trade-off you are making.

You are making your life as a developer easier in exchange massively increasing the resource requirements and battery usage on end-user machines.

It's just bad practice and Electron encourages it.

I feel like if we ever want to be taken seriously as a profession the way structural or mechanical engineers are for example, then efficiency and reliability need to be primary considerations, otherwise we are basically making toys.
> Valeant

I know that name. Valeant doesn't do any r&d. Their entire business model is to buy up rights to, or manufacture drugs that are supply limited, and ratchet up the prices to the maximum that the market will permit. They typically end up selling these drugs at 100k-10m times higher than the cost to manufacture. They've also ceased manufacture of several life-saving drugs because the profit margins weren't high enough for their model.

I am anti death penalty, but I would make an exception for the people who run the likes of Valeant. Profiteering off people with rare diseases belongs in a lower ring of hell than serial murder.
AFAIK the Nord Piano (as opposed to the Nord Stage and others) doesn't have a full synth engine - but rather plays samples.

You'd have to explore sampling the output of the Logic synth, and then converting and loading them into the sample engine on the Piano.

https://www.nordkeyboards.com/software-tools/nord-sample-edi...
Is that supposed to be acceptable?
Tinder for jobs: New app for job seekers in South Africa
The thing that I like about hardware isn't the sound but the UI, like the parent post points out.

The boxes you've sold off are good equipment, but they don't really have all the knobs that I'd want, even if they are powerful boxes.
They could in fact actually open every box to check the contents. 15 million is not some unfathomably large number of boxes per day. It would increase the cost of shipping across the borders that require that additional checking, by whatever amount is necessary to hire and organize staff to do that checking. That increase in cost could be shifted to the senders, and in turn the volume of packages would decrease. Trade would not "shut down," but it would decrease.
SimCopter was one of the most underappreciated Sims ever! Especially fun was loading up the cities you built in SimCity and flying around them in SimCopter. Oh man, good times.
It could be implemented as a local VPN server using the NetworkExtension API.
That explanation of the economics and poor regulatory choices that led to all this certainly makes a lot more sense than the explanation in the other aricle. Unfortuntely, it's also less condusive to thinking that it's all the fault of mass-murdering villains running pharma companies who should be harassed for every second of their lives, and that anyone who even thinks this is worth discussing wants people to die. So I guess it's not surprising those comments are up top and this is languishing near the bottom.
Note to the author: please correct the systematic mistake of "it's" instead of "its". And it definitely lacks a printer :)
I was being a bit facetious about you posting on here, but the point I was making was serious. In advertising there's a thing called the "effective frequency"[1] which is the number of times you need to see an ad before it has an impact on you. Obviously this series of adverts has worked on you - you know the brand and you use it as an example of which ads you remember. If the company is advertising in order to raise the level of engagement they're getting that's a fail; if their ads are intended to get people talking about the company that's actually a pretty good result.

There are more reasons to advertise your business that simply "getting more sales". Indirect communication is very useful.

[1] https://en.wikipedia.org/wiki/Effective_frequency
Noob question, how likely is this to generalize to cases of Parkinson’s not caused by this rare mutation?
> Friend, you're making a lot of assumptions and claims about people you don't know (including me), and have a certain streak of arrogance that is difficult to get past.

This is rich, coming from someone who claimed that anyone who wants a type system in elixir hasn't actually used elixir.

> You are of course free to like or dislike any language you want, ...

This is the most common reaction within the elixir community, to assume that anyone who doesn't put the language on a pedestal dislikes it or hates it. You might want to consider what that actually says about the community and the atmosphere of near unconditional admiration it displays. It's an extremely distasteful attribute for a community to have.

Elixir is useful for shuffling data from point A to point B... That usefulness has its limits, that's it.
A systems-level confusion between 32 and 20 sounds like operator error during input—32 being 0x20 hexadecimal. Maybe they thought the field’s value was hex when it wasn’t?
this seems sensible.

be mindful of your impact, and try to minimize it, but understand that the world we live in was built with different assumptions and it can be difficult to transition overnight (for instance, in a world where burning fossil fuels is not allowed, you might not have moved so far away from your kid's grandparents that you have to fly to visit them).
I'm a career designer with a heavy passion in making design tools better. Worked for a VC, lead UX at a YC startup and currently an enterprise consultant. Background is in UX and UI design and bring prototyping skills with React and Vue as well.

Looking for a technical co-founder to build upon concepts from tools like Framer X and http://sketch.systems. Also open to co-founding something completely different if anyone has a need for design / prototyping in a cofounder
if my coffee maker can do this, what about the other stuff in my house?
First rule: if you need Electron, change your requirements/design and move to something more cross platform like Qt or libui/C++.
This is their convertor below.

$10000 dollars cost £7,867.91

I googled $100 USD to GBP and it comes out as: £7,859.50

Percentage difference:
0.106947%

https://www.mastercard.co.uk/en-gb/consumers/get-support/con...
That's absolutely not true. I've checked websites for every PD I've ever lived in and not one mentions an emergency number other than 911.
Exactly what I did. I tried to write notes in a way that was different than just copying as well, I tried to make them make sense to me.
Generate 100 worthwhile blog post ideas quickly using only free tools
If electron apps' claimed memory causes your computer to go slow due to swapping, you should complain. But most complaints I see on this topic stem from a discomfort over the reported figure by the operating system. With SSDs and modern virtual memory systems the claimed memory figure is not a sufficient measure to infer the resource utilization of a process. For example, if slack has a bunch of allocated memory that is rarely accessed, it's going to (at worst) land on your SSD and sit there, having no impact on your user experience.

If you want to complain about applications' engineering, you should complain not about claimed memory but about things that are directly affecting resource utilization or user experience like power draw or excessive CPU utilization due to poor programming. Claimed memory must be combined with a profile to show that cold reads are common enough for the claimed memory figure to be correlated with a performance hit. But of course, this often isn't readily available without profiling for all but the most extreme cases, and so engineering types fixate on easily visible measures like claimed memory that likely have no actual resource utilization impact in most cases.
What about AI-managed quantum blockchain!
By now, it's probably better to just agree on a new canonical attribution - "Leonard Nimoy, Civ IV voice actor".
way to go! i think you're on the right path.
Electron ships its own Chromium-based browser view. Using the OS provided one does sound like an efficient option, but then you have to deal with all the same compatibility testing (different browsers, different releases, running under different OSes and OS releases) that makes web development suck. It's trying to provide a web-based stack while abstracting away most of those headaches.

It also provides some Chrome specific functionality (loading Chrome extensions) that wouldn't work in an engine-agnostic system, though I don't imagine this is a commonly used mechanism. Extensions are more useful for shoving your own functionality into someone else's webpage, if you control the whole codebase surely it's not the best way to do anything.

https://electronjs.org/docs/api/browser-window#browserwindow...
IoT-controlled huggable teddy bear on Kickstarter:)
ATIS – Automated Threat Intelligent System Integrated with McAfee ATD and MiSP
One of my bank accounts didn't let me change my address online. I had to go to the bank and do it.

A branchless bank must have an alternative
> There, all for free on the web no need to go back to school.

Oh, I don't doubt that self teaching is an option, I've just imagined this particular subfield would place more weight on a degree given that it probably requires more actual CS knowledge

> You'd still be writing code to make the hardware do stuff, just more work to achieve the same. So it might not be that exciting after a while.

Unfortunately I fear you may be right on this. It's a shame I lose interest in my hobbies as soon as I start doing them as work
No, I haven't actually tested it. Maybe it just feels that way. But it does feel that way.
Drat. Uh, I was referencing it by, uh, its thickness dimension. Yeah, that's what I was doing, yes sir.
Is empathy too much to ask for?
Brief Intro to Moving in Vim
> I am having a hard time to see how I can tell people who can no longer afford lifesaving medicine due to profit maximization to value a civil discussion culture higher then their survival.

Tell them to act in a civilised way and to not vote for Trump who clearly stated his stance on public health.

https://www.economist.com/united-states/2016/11/19/illness-a...
Compounding pharmacies don't make drugs, they mix them.
> In 2003, courts ruled companies with more than 50 percent venture capital ownership are ineligible for SBIR grants.

This seems like it would be a rare case, especially early in a company's lifecycle. Any company that is majority owned by VCs is either very late stage, or suffered a down round. Nobody is raising Series A or B while giving away more than 50% of their company to investors.
The Best Book I've Read About AI Isn't in English
I do 100% of my work, but it does not fill 100% of the arbitrary expectation of the time I spend here.
ACT Releases “ACT Assistant” for Amazon Alexa
In "socialist" Netherlands where getting Cancer won't cost you a cent and we basically have Universal income (in the form of bijstand and various subsidies) most people still don't care (edit:) enough to do something with their own money.
"Few tens of millions of open websockets" is more than Slack and Discord combined, not?

BTW: we were the first who did 1M long-living connections load test with Cowboy on a single EC2 instance back in 2011. And 3M long-polling HTTP requests on a single beefy physical server.

It was before WhatsApp upstreamed their optimizations and before Phoenix team made it easy.
I'm not sure what you mean by accuracy.

But no, we didn't do testing of any kind. If the packages got through customs without causing a delay that made people miss their expected delivery date, all was well. It wasn't our intent to do the job of customs, we just intended to make sure that everything was documented in ways that it would speed through. Or, to stop the package before it left its originating city and have the shipper correct it vs. having it go across the country before a problem was noticed.

It was our goal to make the shipping smooth with minimal invasion of people's packages.
Your post is spot on but (pardon my off topic comment) anyone who thinks they need 15k for preschool has not discovered parent coop nursery schools which are an order of magnitude cheaper, and awesome if not way more awesome due to parental involvement.

>people have to room to spend more on

Didn’t quite understand that part.

More on topic, personally I’ve taken on some financial costs and gotten some hedonistic rewards by buying a Tesla. Maybe if people are rewarded for making moves in the right direction, that will help.
TSMC is not based in China.
I would easily forego the niceties explained in the article if it meant there were something better.

The main reason to use Electron is that I can have happy macOS, Windows, and Linux users. Apps that focus on a single platform are exclusionary.
Unrelated: I really hope software like https://github.com/revery-ui/revery becomes mainstream!

This node IPC debugging technique is pretty nice!
I think we agree on the goal, not on the methods. It took decades for these companies to become what they are. If you listen to some people you should just burn them to the ground and go personal vendetta mod on their executives.

What I'm saying is that we should be careful about how we do it, because in fine the "how" is as import as the "why". Things don't happen in a vacuum, you have to deconstruct them and get to the root causes, otherwise you're just rushing to another failed system. Let's say you manage to get the execs out, what do you think will happen ? The new ones will turn everything 180 degrees and sell drugs at loss ? No, why ? Because the whole system is tweaked for profit.

Every time health pops up on HN, the majority of Americans defend their system and criticise the European way. There is a bit of a cognitive dissonance here, people can't expect a private/for profit company to do the right thing when it comes to public health. On top of that the demographic of people who voted Trump very much intersects with the one needing cheap health care, it clearly indicates that people are voting against their own interests in term of health, that alone would hint that there is a much bigger thing going on than "greedy execs control everything".

https://www.economist.com/united-states/2016/11/19/illness-a...
It depends on your goal, there's long term storage that assumes we'll retain the technology and knowledge required to read it (or it will be easily reproduced, ie the reader technology is trivial to produce in the future because technology has advanced really far) and then there's the civilization restart archive that assumes we'll be anywhere from cave people up to basically where we are today. Really for the second type I think both the macro scale and a micro scale (though not digitally encoded for most of it) in combination along with something like the Rosetta Disk [0] from the Long Now project is probably the way to ensure it's actually readable. The large scale text would provide a boot strap to get optics set up that could read the smaller etched text on archives that could then setup the tech to read the even finer etched stuff and so on maybe eventually reaching disks like the one in the article where we're able to store digital files and the knowledge to read them was introduced in more human readable formats.

[0] http://rosettaproject.org/disk/concept/
Tacit: A CSS Framework Without a Single Class
I agree with your statement but just have never really seen it work that way in real life.

Slack is the best example. An app that just 'works' in Electron and the stop-gap became the permanent solution for eternity et voila -> still huge valuation and IPO.

I am afraid once you go Electron, most will stay Electron.
Oh please. Dentistry involves extremely personalized care, with crowns custom-made for every patient (these days by automated machines) and work done by highly-paid specialists on an individual basis, yet the masses are generally able to afford it. Once stuff gets out of the patent phase (20 years), it's going to become very cheap with tons of competition.
The lease paperwork was in the glove box, from memory I think their lease must have cost them near $2 a mile, but BMW ate a chunk too. Dealer explanation is limited market due to range anxiety. Which as I demonstrated above is a non issue for most people.
FlightGear has that, and is open-source.

https://www.flightgear.org/
As long as future citizens can hold people like you equally culpable for the predictable result, sure.

Here is my prediction; no one enters/stays in the high risk drug market because whack jobs want them dead for getting a return on R&D.

In fact, I would take this one step further. You my dear comrade, since you don't work in the field trying to invent drugs and lower drug prices, are obviously part of the problem. Since you rent your labor elsewhere for your own benefit you artificially distort the market and keep prices high.

Since you seem to believe capital punishment is an appropriate sentence, I only ask that you put a little skin in the game and mark your beliefs to market.
Well, I certainly get 100% of my work done, on time and done to a high standard.

But, I would say that my productive time is less than 50% of my work week. I'll do a 4 hour burst and get 90% of my weeks work done, and the rest of the week is touching up a few things and browsing HN/Reddit or whatever else.

I remember reading a short article that introduced (to me) the idea that something like 30% of corporate jobs aren't required by any means. It's just "job creation", all fluff work that could be automated or simply isn't needed. As time goes on and I get more looks "behind the curtain" so to speak, the more inclined I am to believe this. I'll look around for the article and edit it in if I find it. It articulates the idea much better than I.

--

Article for reference: https://strikemag.org/bullshit-jobs/

Thanks wortelefant!
> and you chose to be a random citizen because "everyone else is doing it".

You're projecting. That is not the reason I gave. The reason I gave is that it would cause me either economic harm or reduce my enjoyment of life to do so, for what I perceive to be no practical gain (it does not, IMHO, advance the environmental cause).
There's a pretty serious disconnect between the demand of those that the SBIR program is meant to serve, and the mindset of those actually receiving SBIR grants.

On the demand side - many of the intended customers of SBIR grants (government agencies who need a specific technology solution) can get what they want faster, and with lower risk, through an existing contractor. You could gamble with a two person company funded by a few hundred thousand government dollars, or you could go to a Raytheon or a United Technologies and get the same thing made by a team of experts who will build you exactly what you want. In terms of deliverables, the risk profile is much lower (and the resulting upside to your mission is much higher) if you go with the big contractor. SBIR exists to fund some of the riskier technology efforts, but also to give the government some cover in terms of perceived equality. They can point to SBIR and say "Look, the little guys had a chance to bid too! We even gave them money!"

On the receiving side, I've met more than a few researchers who have gotten SBIR grants for their work, and effectively used them to pay for research/proof of concept that they have already done. I.E. the SBIR grant (Phase I) pays for work that they've done over the past year or so. Many of the folks who take Phase I grants that I've spoken to have no interest in commercializing and productizing their work. They are interested in basic science, not product development.

I'm not sure how to get over what seems like a pretty serious disconnect here.
Eh, what? That is never true, at least in my case. Right click functionality is never good, context menus are useless, text selection, dialogs, etc.

The whole point of electron is to avoid those native things.
Of course it does, but we can say with confidence that attention and capital are misallocated toward a specific, identifiable set of activities. That's rare.
And their messaging around those is correspondingly quite different.
The secret is don't use electron.
How come when I posted this same link on Hacker News, HN flagged my post? Guess the same hive mind that runs Google runs the show at HN.
I have always wanted to look into Ada, but could never see being able to make a serious business case to use it for real things at the moment.
I didn't call it expensive, though. I said the people trying to buy one from us had too much money.
> ... free markets don't work when one of the parties to the transaction has their very life on the table in a transaction.

So why is food so cheap? Why is water so cheap? We need both to survive but nobody is jacking up rates for them.
Massively depends on performance. You get money from a subset of a subset of a subset: there's the set of the audience; there's the subset of the audience that are logged in to Medium at the time; there's the subset of the logged-in subset of the audience that bother to click the 'Applaud' button; there's the subset of the bother-to-click-Applaud subset of the logged-in subset of the audience who actually have a paying membership.

Then how much you actually get is totally up in the air. If mine's the only piece Reader A applauds that month, I get 100% of the revenue (minus Medium's cut, of course - the house always wins); if Reader B has applauded 1,000 pieces this month, I get 0.1 percent of the revenue (as do the other 999 authors.)

It's a model which is inherently insular: of the traffic that has visited the piece so far, 90% is external (and thus earns me nothing other than name-recognition) and 10% is internal to Medium. Only a tiny, tiny fraction of that 10% has applauded, and I won't know what that translates to in terms of Cash Monies until Medium calculates it and tells me. I'd be much better off promoting it to existing Medium members - such as by joining a 'publication' on Medium - and ignoring external traffic sources, but I don't want to do that.

As a ballpark, though, the answer - long in coming - is "not much, but considerably more than I'd get on Brave." The Raspberry Pi 3 B+ benchmarking piece I wrote on Medium has earned about $277 lifetime; if this earns the same, I'll have done very well indeed.

Thankfully, I'm not relying on the Medium income: I've pieces in various websites and magazines based on the same core data, which pay one heck of a lot better!
Technically as long as the exponent is greater than one it's still exponential growth. But the rest of what you say is on target.

Edit: I'm laughing about the state of maths education in the US after getting downvoted!
I don't see proprietary hardware+software bundles counting as a way to "give data back to the people".