skysight-inc/HackerNews huggingface dataset:
What about some specific trait present in both parents, that will get worse in the child if both parents have it, because it’s a phenotype influenced by the number of copies of a gene the parents each have, and the gene is dominant? Cystic fibrosis, for example. Be nice to just slice all the copies out and start fresh, so that the child isn’t even a carrier.
If you have a to-do list that is public, and nothing gets done, that is your accountability right there.
Some unfortunate changes to UK pension laws mean that for some people who hit the - you have to retire or change jobs as you would get massive tax penalties.

One of my friends to early retirement from BT as other wise for his remaining time he would be working for a pittance
That suggests to me that there's a conflict of interest in the NSA's mission.

Perhaps it's not wise to have the same organization looking after both the defensive aspects of our security, AND also offensive espionage operations.
With presence, a manager's minimum qualification is being capable of comparing "number of hours in attendance required" vs. "number of hours present". Remote work raises the required minimum competency of managers, which most companies will avoid at all costs.
In a professional environment, I've always been able to take off for such things whenever I wanted without such things. "Hey, boss, I have to run to the bank. Be right back," was all that was required. I really didn't even have to tell the boss. Often a co-worker or a secretary would do.
In-Q-Tel taps Forge.AI to predict impact of world events for govt agencies
> Onshore wind is already much cheaper than than nuclear.

Except that it cannot possibly produce enough to replace nuclear or meet demand.

And nuclear is not more expensive than _offshore_ wind, which will also struggle to produce enough.

As discussed in this thread, people keep ignoring that raw cost per kWh is just one of the parameters. Another key parameter is that production must be able to meet demand.

At the moment it is simply not possible to operate only on wind and solar.
This becomes is more true when you account for the boom in electricity needs that is coming because electric cars.
Thanks for sharing your typeface, but you should not claim ownership/creation for a typeface conceived in the LEROY Lettering system. My dad used LEROY as a draftsman in the 50s through 70s so I find their claim pretentious. Please research before stating your claims. Thanks.
No your not. We’re building products with remote teams and I’ve to tell you compared to co-located teams it’s just pure hell. My conclusion is: either everybody is remote or the team needs to be co-located entirely. The middle ground results in entrenched warfare between the 2+ parts of the team.
There's plausible deniability and then there's sheer barefaced denial. When will the Better Ads Standards protect the average user from having outright malware, browser-jacking, click-jacking etc. etc. delivered via ad networks, potentially including Google's or Facebook's? Do that and 99% of web users will most likely stop caring about any other sort of ad blocking. However, as things stand today, switching to Brave, Firefox or any other browser that commits to making all malicious ads blockable is the only reasonable course of action.
Okay, I understand the arguments against this bill and can sum them up easily; patents are meant for inventions whereas these are discoveries. Genes and their properties exist in nature and the discoverers stumbled on to them through some variant of effort and random chance.

Logically, if they exist by default and we are making observations about them, then how do we get to patent/own the very idea of them? An absurd parallel would be Charles Darwin patenting a giant tortoise - an entity that exists in nature - upon his discovery and requiring a license fee each time a natural history museum displayed one.

But that's one side of the story; what's the argument for the bill? Is there a logical reason why the patent system should be expanded to include entities you observe in nature?

I am sure the above can be formulated with more precision and panache, but as far as I can tell, I'm not sure what the equivalent set of ideas are for the people arguing for this bill. The best that I can come up with is an appeal to utility (i.e. it would incentivize X, Y or Z). However that's not a strong enough argument - what's the "steel man" that's missing from this conversation?
I use vimwiki. Simple, light-weight, and does exactly what I need. I also use org mode in spacemacs with evil, but so far I haven't come across any functionality in org mode that I needed that vimwiki didn't also provide.

https://github.com/vimwiki/vimwiki
That's depreciated and won't work in the next Safari version, along with all other normal Safari Extensions.
I agree! I love being work remove work a day here and there. But the idea of completely remote gets a thumbs down from me.
Protobuf would be an excellent serialization. It's compact, binary, and efficient. There's a ton of library support in nearly every language imaginable.
U.S. Citizens Are Dying and We Can Save Them
This is ok if you can upload preprints on arxiv or equivalent. The obsolescence of papers already happens now, when a conference is 6 months after the submission, and the preprints system works fine.
It's never gonna happen. It simply is not Apple.
> in the UK, at least, you could argue we're left paying for a generation of Baby Boomers who are swanning about on cruises, golf days and health spas on pensions they never paid even half towards.

There is a massive (and sadly too common) social bias in this comment: this is not the life of retired baby boomers, this is the life of retired upper-class baby boomers, but the majority of people isn't like that.

The upper class people also live a lot longer than the lower one (a decade or more depending on the region) so they cost even more.

And since they are generally in a much better shape at the same age, raising the retirement age affects the lower class much more than the upper one.

Also, the life expectancy didn't change as dramatically as you'd think since 1950 in that context: in 1950 the life expectancy of a 60 years old British citizens was 77 years. Now it's around 84 years[1]. It rose, but not that much (it didn't go from 5 to 20).

[1]: https://ourworldindata.org/wp-content/uploads/2013/05/Life-e...
Believe it or not, its been happening. In fact if it isn't automated and is of any size, then it's been outsourced to Asia. When it grows to a sufficient size to warrant the fixed overhead of automation, it may return to the western world. But without the assembly-line jobs, giving lie to the idea that bringing factories back will create (many) jobs.

The 1% of 'old factory jobs' that are retained (Engineer, planner etc) won't employ many people.
Pregnancies at 16 have very real health risks and 16 years old are not ready to be parents yet, not ready to be independent either. There is nothing curious or odd about the end.
It's because a certain segment of america does not wanna believe that people could vote for Donald Trump unless they were manipulated, so they need a scapegoat (FB).
Why blockchain is not a trust machine
Two (somewhat competing) thoughts:

1.) In the grand scheme of things, a company that books travel sharing your info with a company that provides rides isn’t the worst thing to ever happen in the world of privacy and interviews. You could take the nuclear option, which would involve naming and shaming Pana and potentially writing some letters. Depending on where you are, this could violate some privacy legislation. Or, you could decide that wasn’t too far out of line and merely ask Uber to delete your info and stop emailing you. And, you could keep the nuclear option in mind if they don’t respond.

2.) Anecdotally, the interview stage is the best that a company will get. If they’re already doing things you consider sketchy, I promise that things won’t magically get less sketchy when you take the job. I can think of two ‘opportunities’ I could have saved myself from if I had internalized that lesson.
Small nitpick, but patents protect novelty, not uniqueness. If someone creates a human gene that is not available in nature, then it is novel.
Sorry but I can't make the switch from chrome to ff because I don't buy ff's agenda any more than I do Google's. Neither is in the browser game to make money from great browser product.

I want someone to be as dedicated to the product as id was to doom. I want to be able to use their browser for free for a year or three. If I still like you then I'll mary you. Then I'll pay a yearly fee for as long as I live.

Edit: until you start to act a fool. If you do then you're out. Can someone please create this product?
If it was just the first point, the customer should be able to confirm that the activity was intended without even going through human review. It should be like when your bank texts you to confirm an odd transaction. They don't simply lock your account.

It sounds much more like it was the second point, which is unsettling. It's one thing to plan your pricing based on the assumption that most customers won't maximally-utilize. It's another thing to enforce a soft-limit that's vague and below what was advertised. I'd much rather have a lowered, known limit than whatever this is.
> - Profile stuff like History and bookmarks is shared across containers and securely synced with client side encryption by default.

That's actually why I prefer the full profile option in Firefox (i.e. running 'firefox -p' and selecting a profile). I don't want shared history across profiles.
Boycott is often the only solution. That's why those articles are important.
These things happen. I mean, how many council politicians are killed any given week? Two, three? I don't understand the relevance of this
Electrum Phishing Attack 2018-2019 – A closer look into the stolen funds
Seems like one set of researchers has had two breakthrough studies of bee intelligence. Has anyone reproduced this? I feel like for something this incredible, we should perhaps wait until another team can reproduce the results before getting too excited.
You’re mixing inflation adjusted versus non inflation adjusted numbers. $70,000 is adjusted for inflation. Housing costs have increased faster than inflation in some places, but not by a factor of 10. Indeed, nationally, the price per square foot for housing has stayed pretty stable for the last 40 years: https://www.supermoney.com/2019/01/inflation-adjusted-home-p...

There are two aspects to that trend:

1) People are buying bigger houses. That is consistent with the fact that they’re making more money. Instead of just having extra money, they’re buying bigger houses.

2) People are buying new houses in the south, where they’re cheap. That makes sense too. A house in Palo Alto is a lot more than it was in 1970. But Palo Alto wasn’t Palo Alto in 1970. Today it’s East Egg. Your $2.5 million is buying you into a haven for the elite. But back then, it was Round Rock. You were buying into a nice, but otherwise ordinary suburb. You can still buy a nice family house in a good school district for $250,000 in Round Rock.
I think that the issue is not whether remote work sucks, or working in an office is superior, but it's more about hiring the right people. This gets a lot harder when hiring for remote work, which is why many remote companies require previous remote experience.
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We are hiring for several positions (full stack engineers feel free to apply to Frontend and Backend positions):

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* Data Engineer (Semantic Knowledge Management) - NLP, NLU, PostgreSQL, experience with medical taxonomies/ontologies, Clojure (ideally) - https://jobs.lever.co/reifyhealth/d4d1bd8c-c82b-47e7-9e15-f5...

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We value diversity and believe the unique contributions each of us brings drives our success. If this sounds exciting, we'd love to hear from you!
I'm in my mid-40s and I'm already burned out on work. I am desperate to retire. I can't imagine working past retirement age, just because I am still capable to do so.
Again, DNA should give some answers. About the relative timing of precursors to feathers for instance. Or ancilliary genes/proteins to feather production - are they used for anything else? All this could point to feathers-before-flight. Not such a dumb question?
> I sense some frustration about the language... what happened to make you so anti-Go?

That's an utterly pointless derailment.
I also recommend this book. One of my PhD students is using it to learn Bayseian models on her own.
> I am sure the above can be formulated with more precision and panache, but as far as I can tell, I'm not sure what the equivalent set of ideas are for the people arguing for this bill.

"But then why would those companies finance the research to identify and understand genes ???"

Yes, the answer to that takes about 10 seconds (less if you're aware of the concept of gene therapy), but that's mostly all they have to go from.
Aren't the queries case insensitive by default?
Yes, actually. But I didn't want to bring it up.
These are definitely real problems.

It's possible to have a remote company that only hires employees in one or a few states, though. As an employee, I would much rather work for one of those than one that required me to work from a specific office.
I understand the challenges at scale, but there's definitely a decade-long trend towards locking down devices and software from user changes, because any API or configuration that's accessible to knowledgeable users is also accessible to malware and social engineering.

This coincidentally aligns with business goals (watch our ads, replace your phone every 2 years, sync everything to our cloud because anything else is risky and cumbersome, do not integrate our devices with a non-blessed solution etc.) but for some reason discussing these goals is frowned upon.

Correlation does not imply causation, but an event can have multiple causes at once, and only some are allowed in polite discussion, and not everything should be attributed to only malice or only stupidity.
Amazon support is from everything I've heard and experienced great.

So don't lump everyone together in an attempt to paint DO in a better light when it's not true.
Fortunately none of those two issues are relevant where I live. That sounds very tricky indeed.
I used to work a few months at a time from my home office in another country. It worked fantastically well. I like to be able to concentrate without interruptions, and, as the timezone was different from the office, I got a very nice overlap where co-workers would provide work for me as they left for the day, and I would have that sitting in my inbox when I started working. Then, when my day was over, they would have the work ready for them when they got in (for that kind of one-day jobs).
Of course there was also video conferences and such. But, as our customers are everywhere anyway, it didn't make any difference if one or two of us from my company were in different locations when we had video conferences with them.
Are remote contractors easier due to how things get billed out? I am assuming that puts the accounting burden on the contractor instead of the employer.
Yes I have a decent amount of savings. About 5 years of runway if my income remains $0. I wrote in detail about my financial preparation here: https://danielvassallo.com/from-employee-to-bootstrapper/
Don't most animals have the ability to learn associations? E.g. when the leash jingles the dog knows it is time to go for a walk. Not sure this is the same as humans doing arithmetic. Scientists seem quite anxious to make the jump from associations to human level abstract thought, for some reason.

Not saying it is impossible, but these kinds of studies seem very handwavy and not very careful with terminology.
This is really cool.

One suggestion. Allow the mouse to control the spaceship movement in both x and y directions. It’s intuitive to try to point the mouse to the place you want your ship to go, however the mouse only controls the Y axis.
It’s a nice fantasy, but nobody in the US is going to FIRE based on giving Uber rides without being very nearly in a financial position to FIRE without it.
Very good write up on the Chrome ad blocker issue, and worth reading in its entirety.

Based on the comments in other posts on this topic, my view is a little different. I think Google is making decisions that look good in short term models but will be very damaging to them in the long term. In this case, it is simple. If Chrome does a poor job blocking ads they are going to become known as the junk browser.

Recall a behavior Google added to Chrome. When you open Chrome, you are presented with what looks like a default Google.com search page. When you click the search field and start typing, instead of appear in the search bar, the search occurs in the URL navigation bar.

Google could have trained their users to be certain they went to Google.com to make a search. They didn't. Today Google pays billions of dollars a year to Apple. Google still doesn't seem to have learned that lesson (see AMP and weird ideas on divorcing the URL from the site the user is on.)

Not only is Google's revenue growth under threat, but their existing revenue base may very well be too. After GDPR, the EU copyright directive, and changes Apple is making to Safari who knows what 2020 revenue will look like. In my mind, this explains a lot of the sloppy decisions Google's management has been making.

If there was no Firefox or Apple, then panic. For now, the panic should lay within Google.
You can get permanent residence after 5 years in the Netherlands too, and the language level required is pretty basic. It's not very hard to pass the required language tests within 5+ years.

The limit to one nationality is maddening, however.
Absolutely. This is what I do. I travel every second week and for a long time I just have a carry on.
you're conflating issues.

feature lock-in, and not feeling empowered to ignore the cloud services associated with the cellular phone you bought, are concerns. they are not security concerns.

it's privacy built on a closed source platform. that's the point you're making.
We just need to lose the idea of an 8 hour work day. It's an anachronism from the industrial revolution. Make me come in at 10AM, have standup, maybe a meeting or two, have lunch with colleagues, then everyone leaves by 2PM to work on their respective tasks. The problem with full work from home is that some people take advantage of it more than others, and you lose out on a lot of the "firm effect" that comes with face to face communication. The problem with 9-5 is rush hour, burn out, and inefficiency. Force everyone to show up 5 days a week for 4 hours and you get all the benefits of both.
Maybe you should look at the Pro displays instead of some consumer TVs?

Btw Apple said other lies there too(i.e that Sony sells only small<17"> pro displays).

You may also wonder why Apple put an OLED display on its flagship phone instead of a LED one.

Prediction: next Apple display will be OLED and they will make it sound like they invented it or are first to use this tech...just like they did with Apple TV 4K(even if 4K was already old/common tech at that time)

https://www.marcotec-shop.com/en/sony-bvm-x300-oled-monitor-...

https://pro.sony/en_FI/products/broadcast-monitors/pro-monit...
Interesting topic. I haven't gone as deep in this rabbit hole but I've also written "similar" tool that I've used as a visual help [1] when reading programs written by other people. It's been useful in understanding bottlenecks and weird code patterns / dependencies. I've even printed the graph sometimes and written down notes on the paper, drawing circles around logical groups, etc.

I ended up going with separate color for each type / package.

[1] Screenshot of a simple piece of code: https://imgur.com/a/Pr9dkkd
I think a big issue is that the costs and benefits are unevenly distributed: the benefits fall mainly on the employee, while the costs are disproportionately on their boss (since managing remote workers can be considerably harder). Since the boss is the one making the hiring decision, this asymmetry means remote hires are a tough sell.
It is at least notable if it wasn't previously.
Agreed. Sometimes I have heads-down days, where I really just want to immerse myself, and being around coworkers is distracting. And sometimes I have less structured days when informal conversations are more necessary. These are roughly analogous to stages of a sprint or project, so they're roughly synchronized across the team. Fully onsite and fully remote are both suboptimal.
I have learned a lot from HBR, but i also find it's skewed, rightfully so, to larger corporations.

I enjoy https://firstround.com/review/ quite a bit. Excellent quality articles.
I feel like no amount of effort on a superior engine will be more effective than Google targeting their own browser for their own apps. The experience using basic Google services like search on Firefox mobile is much worse. You get access to fewer features, like looking for shopping results nearby or setting your location for shopping results near by, and I'm pretty sure it has nothing to do with the technical capabilities of the browser.
Visual Studio Code with a Full IDE Using Safari in iOS 13
Look around you. You're surrounded by goods you could afford only because automation made it so. So sure, you can say "all the automation money is going to business owners pockets", but you're surrounded by wealth made possible by automation.

> If you live in a hardcore capitalist country like the US all the automation money will go straight to the business owners pockets.

Let's look at this through a moral lens. If you come up with an automated way to make mouse traps, who should profit from your invention? If you came up with it on company time, the business owners should. If you came up with it on your own time, then its yours. Diverting that money anywhere else is immoral and disincentivizes future inventions.
There doesn't appear to be an intellectual underpinning in support of the bill. What does exist are the usual platitudes about promoting "innovation". I'm surprised that the "threat from China" hasn't been invoked yet by the various bill promoters though I expect that in the days and months to come it will be.
7GUIs: A GUI Programming Benchmark
The other answers are right, but the best part is- that was literally hacking lol
Care to explain how it's a human gene if it's not available in nature?
Both of these sure sound like ripe b2b startup opportunities...
Scared to Handle Risks? How to Take a Risk for Your Business Growth