skysight-inc/HackerNews huggingface dataset:
> how does the „two copies“ phenomenon of the human genome and the „two copies“ thing of chromosomes fit together? Are those one and the same concept?

Which phenomena are you referring to exactly? That we have two copies of each chromosome and if they mean we have two copies of the human genome?

> Are there two copies of the XY chromosome, too?

Each of our non-sex cells[1] contain two sex chromosomes: one from our father and one from our mother. Since your mother always inherits her X chromosome, your sex is determined by which sex chromosome you got from your father. If you are a female (XX), your father passed on his X chromosome. If you are a male (XY), your father passed on his Y chromosome.

This rule makes for some interesting inferences. For example, your father in turn got his X chromosome from your grandmother and his Y chromosome from your grandfather (both on your father side, of course). Your mother, on the other hand, got his X chromsome from both your grandparents on her side.

So if you're a male, your Y chromosome was passed on from your grandfather on your father's side. If you're a female, one of your X chromosome comes from your grandmother on father's side, but your other X chromosome may come from either of your grandparents on your mother's side.

You can trace this Y-chromosome lineage back to what's called the Y-Chromosomal Adam, which is the last universal common ancestor of all currently living human males[2]. You can make a similar inference using your mitochondrial genome[3] and arrive at what we call the Mitochondrial Eve[4].

Our sex cells[5] are different, since they only have one copy of our chromosome set. The number of the chromosome set we have is called ploidy[6] and so our sex cells are haploid cells, as opposed to our non-sex cells, which are called diploid.

If you're a male, a single mature sperm cell in your body contains either the X or Y chromosome. For females it's different, since they only have the X chromosome, all their mature cells contain only one copy of the X chromosome.

[1] https://en.wikipedia.org/wiki/Somatic_cell

[2] https://en.wikipedia.org/wiki/Y-chromosomal_Adam

[3] https://en.wikipedia.org/wiki/Mitochondrial_DNA

[4] https://en.wikipedia.org/wiki/Mitochondrial_Eve

[5] https://en.wikipedia.org/wiki/Gamete

[6] https://en.wikipedia.org/wiki/Ploidy
Thanks, the feedback has been good in general when I've showed people it. My plan was to start filtering by the current filters, and then if it works out I can have additional filters (think of it as an "advanced filter") where you can be really specific.

Everybody has their own preference, and I'd love a jobs board that lets you actually search by those preferences.
Amazing! One of only 5 Flying Ace pilots in the world. What a legend!
I suspect your question has an unmarked asterisk, which is that the students end up with similar standardized test scores and GPA. For that to happen, it must be the case that a student at the good school can get good grades while learning only half the material, which seems not possible.

And so the answer is that colleges already can and should take into account % learning through GPA.
Kotlin – Anko and the Commons
How about we make executives only responsible for acts that can’t be traced back to individuals under them? If a bad employee fucks up and makes a false police report, nail him. If the entire organization fucks up and you’ve cleverly designed it so it can’t be pinned on anyone in particular, nail the person in charge.
Mental health problems are seen as a weakness in this country. It's very anti the American way to:

1. Have a mental health problem

2. Seek help for a mental health problem

This leads to insures being able to deny this, and it not seen as a negative, because it's denying something that's weak. And weakness in the USA is the ultimate sin. Homelessness/Joblessness also fall under this same belief system.
It plays just fine on my W10 FireFox
How much money do you realistically see this generating? With how much effort for marketing and polishing? I would be impressed if OP could calculate even 1 dollar per hour and come out with a profit.

This is a niche of a niche of a niche.
I think it is an amazing achievement by Tesla that these hit pieces cannot find more than a handful of incidents going back 3 years while there are half a million Tesla’s out there. Their quarterly safety statistics is a great strategy to counter the propaganda that “Tesla cars are unsafe” or that “Tesla cars caught fire more often”.
In my career I've found that knowning "enough" about a lot of fields (often self taught) has led me to invent valuable things that experts in any given field would have never discovered. Things with many millions in sales.

Also I've found that experts in some field will say something is impossible that I, not knowing it's "impossible", will try to do anyway and find a way to do it by applying techniques from outside the field.

I feel these are my "secrets of success", other than a lot of hard work and persistence. :)
Kotlin – Anko and the Layouts
I don't think I've ever seen a longbow in person. I love the art on them though.
I second this. His videos are phenomenal
Of course since Microsoft owns hololens and and open source AR strategy, they’re motivated to do this well.
AMD was also measurably slower to begin with, in terms of per-core performance. Not just by some small number; depending on the benchmark the difference can hit as high as 40% on the latest architectures. What they lack in single-core perf they make up for in a vastly superior multi-core architecture.

Also, something everyone seems to forget: All of these cloud providers are running Skylake chips, which were launched in 2015. Google Cloud in particular will even give you chips OLDER than Skylake by default if you don't specifically request Skylake. Even assuming instances like an AWS m5a are running on Zen 1, not Zen 2, that's a 2017 architecture.

So you're presented with all these graphs that say "AMD only lost 5%, Intel lost 25%, fuck Intel" but the reality is that Intel was previously far faster than AMD, and they're not even fabbing their best designs for the data center. Intel definitely had more vulnerabilities and they WERE hit harder, but its more nuanced than just blindly wondering why more cloud providers aren't making a fleet-wide switch to AMD.
Yes, this possibility has been teased many times before. On top of my head
- Arrest of "33-åringen" days after the murder
- Gert Fylking's article about Christer Petterssons admission to him
- Pelle Svensson about "bombmannens testamente"
ACL 2019 Reports Record-High Paper Submissions
Since there's not much info on this, and since I missed the relevant thread last week, I'll just note here for the record that Mojang's other recent release, a browser-based retro game called Minecraft Classic, was built on my voxel game engine.

[game] https://classic.minecraft.net/

[engine] https://github.com/andyhall/noa/

if anyone's interested. It's pretty weird waking up one morning to find out that Mojang built a game on your tiny solo project...
Natural compound found in broccoli reawakens the function of tumor suppressor
Hah OK fair, I admit to skimming. That "can't identify the top-level official responsible for his ticketing" excuse is pretty odious, good god.
The CSS text-reflow engine (which ePub relies upon) doesn’t spend nearly as much time on the layout of your page as e.g. LaTeX. Thus, the results are vastly subpar to putting the book through a professional rendering engine, outputting to PDF with a page size targeted to the given device.

This isn’t anything to do with PDF, of course; it’s just representing the baked result of a text rendering process. Your device could do that rendering itself just fine; it’d just take a while (much longer than it takes to change font family/font size and see the result in your favourite eBook reader.)

It’d be interesting to see an ePub-like standard that kept the text as semantic text, and rendered “at runtime”, but not “in realtime”; rather using a set of render preferences you set up before-hand to render the book once when you first download/sync it. Sort of like how runtimes like .NET dynamically recompile downloaded bytecode to native code to “specialize” the code for the device they’re running on. With such an approach, you could rely on a render-model that actually spens time doing good, constraint-based rendering of the text to avoid rivers/widows/orphans/excessive hyphens/etc.

You could get pretty far in cutting down the perceived time of this render by just splitting each work into chapters and rendering a chapter at a time. You would be able to start reading once the first chapter finished rendering. Which, for most normal types of books, on the sort of CPU an eBook-reader has, would “only” take ~10 seconds.
> I've never heard of a break light being out either.

LED lights are slowly reducing this, but I don't think I can do my 20 minute morning commute for a week without seeing at least one car with a burned out brake light. How is it possible that you've never seen or heard of it?
Playback lasers can also weaken over time. Not so much a property of the CD as the playback device.
Inferring JavaScript Types Using Graph Neural Networks
Here: http://www.nhlbi.nih.gov/files/docs/public/sleep/healthy_sle...

I'd also recommend earplugs and a good blackout curtain.
I agree that it's not really needed in the Linux world, but I disagree with your conclusion about the reason.

It addresses libraries the same as anything else, make the libraries also fat binaries and there you go.

The bigger issue I see with it is that fat binaries really only make sense when you only have the binary and are giving that directly to untrained users. It was great for Apple because that's exactly how their platform was used, and through their various architecture transitions fat binaries significantly eased the pain because users didn't have to care which kind of Mac they had.

When you have a package manager style infrastructure that builds from source like every meaningful Linux distribution, suddenly it doesn't really offer anything in most cases. Users just ask the package manager to install something and it deals with the architecture stuff behind the scenes. Unless you're trying to create a single disk image that boots on multiple architectures it's just needless bloat.

From a technical perspective I love the thought that it'd be possible to build a single disk that could boot on any platform anyone cares about, but from a practical perspective I can't see any real purpose for such a thing to exist beyond "because we can".
> Doing research, writing it down, making a book, none of that needs to be free.

That works in some cases. I get paid for ghost writing articles and books for business people. They usually publish for free to make themselves look clever. But no one would claim that the result is independent or motivated by artistic creativity.

Your model is fine for hackwork and what is essentially marketing, but that's about all it's fine for. No one would have paid $INSERT_FAVORITE_NOVELIST to research and write their novels if they knew there'd be zero chance of making a return on that investment.
I used National once in Atlanta and vowed to never use anyone else even at a higher price. Great user experience and helpful people.
Apparently a growing number of us aren't.
I'd imagine the 'customer service' people at insurances companies would also need mental health care after breaking the news to their clients...must take a toll
I binged 70 hours of Game of Thrones in 10 days. Here's what it did to my brain
Old-School Tech Skills Continue to Top Employer Wish Lists
Ryzen only has 20 PCIE lanes, it's not that much. Basically the same as Intel since Intel uses DMI 3.0 (basically pcie x4) for communication to the chipset. So on Ryzen you get 16x lanes directly to CPU + 4 to chipset where it multoplexes, and on Intel you get 16x lanes directly to CPU + dmi3 to chipset which multoplexes to pcie.

Threadripper has 64 lanes, though, which is definitely a lot.
>>”we’re investing a ton in the people who come here for higher education”

Don’t foreign people coming for higher education pay tuition fees out of their own pockets?
>Preferring to die by human error instead of shitty software doesn't make logical sense to me

It certainly does if both auto pilot Tesla’s and standard vehicles are resulting in death, but the law will provide a remedy to your survivors and heirs in one instance and actually turn around and hold you liable in another instance.

After all the post was about liability and clearly nothing to do with how the poster prefers to die, which you somehow read into it.
But how do you find these business who are established, but have problems that can be solved. I don't want to be the guy who has a solution in search of a problem.
Maybe? At 20%, it depends on how accurate Mexico’s numbers are. By absolute numbers, surely.
I think many of us curate a physical or digital collection and also subscribe to a streaming service.

I use Google Play Music and when I find something I like, I buy the CD.
Cartels Are Keeping Internet Access Down and Driving Prices Up in Africa
What YIMBYs Get Wrong About Housing
> Someone has to be last

That makes it possible, not likely.

For any population N > 2, it's less likely that you'll be last than that you will not be last.
Eh not quite. Only HW1 Model S did the sign recognition based on camera, HW2+ currently just uses GPS database.
As soon as they can use a mouse and keyboard or controller. Seriously though, there's no mature themes in it at all, and if the gameplay is too difficult there's always creative mode which is literally digital legos.

There's also a multiplayer where they can connect to servers and play with other people. That's where you might want to use some discretion, as the experience will vary from server to server.
Am I right if I assume that Flutter for web will not be SEO friendly?
american exceptionalism
> Then there is also a problem of software preservation: How can people today or in the future interpret those WordPerfect or WordStar files from the 1980s, when the original software companies have stopped supporting them or gone out of business?

This issue in particular we have great solutions for (open formats / text), but they are of course less profitable than only-my-app-can-read-this formats.
Great discussion. However I'm don't find Rodney Brooks arguments very compelling.

See, near the end, the reply by Alison Gopnik.
I haven't actually used triggers myself, and I do feel like they're too far away from the data to be visible/easy to understand.
Seems like Threadripper 3 might be delayed until 2020, so no 64c HEDT for a while...
In my experience a related obstacle to obtaining mental health services is that the insurance companies require that the records from therapy must be available to the insurance company so they can verify the services they are paying for. Meaning, the notes from deeply personal discussions with your therapist and any resulting diagnosis can end up in the hands of your insurance company. Once this information has left your therapist's office it can end up any number of places. While that might be a risk I am willing to take with my social security number or other personal information the deeply personal topics discussed in therapy are not worth risking.

I don't see how this gets any better with single-payer/government funded funding routes. I don't want anyone to know what I discuss with my therapist much less a soulless corporation or the government. The avenues this could open up for oppression from corporations and/or the government sends a shiver down my spine.
Perhaps, but what performance did Intel actually promise that you'd be able to argue against?
I wish I could get a handle on what I needed to learn in order to understand this stuff. I dug out my old undergraduate calculus textbook and started working through all the problems; I'm about halfway through now, but terms like "lattice", "zeta function" and "Laplace transforms" are still greek to me (sometimes literally).
> Everyone is left to implement them over and over.

This is a good summary the state of developing anything Golang
True, but though this may sound arrogant, this reinforces my belief that people are generally too stupid to think about cause and effect rationally. Nearly every time I or my family have to deal with the US healthcare system I end up lamenting it's insanity, from lack of transparent pricing, lack of care follow-through when my elderly relatives are treated, the super high expense for simple visits or procedures, etc. And I'm someone with good health insurance.

To go through this system and think "well it couldn't possibly get any better than this" makes me think one's capacity for either self delusion or idiocy knows no bounds.
I listen pretty much exclusively to extreme metal and punk rock and Google Play Music has been doing an incredible job of recommending new music that I enjoy.
I can't speak to construction in particular, but my statement is 100% true for low-wage ag labor. See https://www.huffpost.com/entry/wisconsin-dairy-industry-undo... for examples in the dairy industry.
> Release your book as an EPUB rather than a PDF. PDF has the reputation of being view-able "everywhere", but it's not exactly pleasant to read on anything other than a computer screen or a large tablet.

One compromise is to target a reasonable screen size in the PDF layout. Set your margins for a 6" viewable (or whatever you like to optimize for) and you should still get a reasonable experience on a tablet.
The difference is that empty spaces really are a good place to plant strawberries.
This is great! The Expanse has a similar theme around the EAILD, they have the protomolecule instead.
It's one of those strange instances where both 'sides' seem to be sides of the same coin. Like vanilla or chocolate ice cream; ostensibly very different, except both are ice cream. It really feels like neither side has the best interests of the public at heart.
Solo modes: whenever they can manipulate the interface.

Online/shared server modes: when they understand the evils of the internet well enough to be safe.

Setup and admin a server yourself. Watch how they play. Dont let it get too big. A dozen or two per server. Dont let them play with thousands of total strangers. That always ends in tears.
The thing he said before that it's a non-swappable integration of a highly-complicated, web browser. Firefox is a mix of Rust, C++, and C that Mozilla Corp. develops with over a 100 million dollars a year worth of developers. The standards it implements are numerous with many complex interactions, optimizations, security features, extensions, and so on. And you are saying it's excessive to pay a Firefox developer to made the change or consult on how it works? That instead use an internal developer with no clue about it?

A Firefox consultant in that scenario sounds more like a necessity than an excess to me. If anything, one expert might not be enough given they're probably specialized to different parts of Firefox. Also, a reason to never want a non-swappable dependency as big and complicated as Firefox. Then, you might become one of those companies that get locked-in like customers of IBM, Microsoft, and Oracle.
A couple of ways I do it:

* Use the Shazam app on my phone to identify music I hear in public places

* Go on Rateyourmusic.com, look up an album I like and find what "lists" RYM users have put that album on, or what message board posts have cited that album. It's a much more "human-centric" approach compared to websites where algorithms generate the recs.
This is something I've been thinking about recently, although more in the context of why imagination appears to be more vivid in youth.

I thought that it may be a cognitive side effect of learning. The more we learn, or more generally speaking, the more information we receive, the more we might reject creative thought as incoherent with, or irrelevant to our environment.
This is a loaded question with many different factors. One factor is privatized insurance is only concerned about turning quarterly profits over providing care. Additionally they are not held accountable for unethical practices as they continue to break the law without any ramification.
If I'm offering it as a platform as a service (instead of VM/container as a service) then this adds significant costs.

Interesting take: It's better to offer it as a "one click app" aside a basic cloud (docker/kubernetes) platform if you don't want to suck these costs.
We already have different speed limits for different users in some highways (for instance, one major highway near where I live has a limit in some places of 110 km/h for cars and 90 km/h for trucks and buses), so there's precedent. But I believe that, at least initially, speed limits for self-driving vehicles will be lower.
> the exact opposite of tesla's entire marketing strategy

Citation needed. Do you have any examples of Tesla’s marketing strategy indicating that “you can sleep at the wheel”? (Not what they predict of the future of the system, but about it’s current state)

The term autopilot comes from the avionics industry. Correct me if I am wrong, but I am pretty sure a pilot cannot go to sleep while auto-pilot is engaged either.
See Lyotard and his notion of Grand Narratives. The uniquely American Self Made Man conveniently overlooks wealth accumulated by men vis a vis free labour. To constrict these men, to suggest their wealth wasn’t “earned”, is to deny the other men of lesser social position of the “opportunity” to do so themselves.

That is, the myth perpetuates the energy that permits the men running these insurance companies to make billions. All reinforced by the whimsical meth-addled pipe dream that “I could be king too, one day” of the legion of white men of lesser caste.
I would imagine the credit card usage forms the majority of the chilling effect. Personally, I find it a lot more annoying to faff around with using the credit card to pay for something (even when I consider the cost negligible) than to just download it.
<sarcasm>
Because they do not like it when Goverment Regulations work in their favour. They love their right to have freedom to choose guns, big corporate bailouts,poor healthcare.
</sarcasm>

On a seriously everything including regulations have a place in civil society.
Machine Learning, Iris dataset JSON version
> He’s lived a long and fulfilling life, a life I want my daughter to have.

I've only worked with three students with spina bifida in my career in special-ed but everyone of them was a positive-optimistic child with a lot of emotional intelligence. Everyone wants to befriend them because they are funny and kind.
A thing to note is that "non-vegetarian" for Indians and say, the US is very different. Being non-vegetarian in the US means eating meat every day, pretty much every meal. In India, there are a lot of people that only occasionally eat meat, say about once a week, or a few meals a week. There are a ton of vegetarian only eating places which are very very popular with the so called non-vegetarians.

Another difference is that meat based meals in restaurants are more expensive than their vegetarian counterparts(like it should be), not subsidized like in the US(through the form of animal meal subsidies like corn).

It would be nice to see per capita consumption of meat products among non-vegetarians of different countries.
How would the sacrifice be for naught? The kid is presumably smarter and harder working and better prepared for success no matter what college they go to.

But for college admissions, I don't think it is unreasonable to judge a kid for how well they did relative to the advantages they were given.