skysight-inc/HackerNews huggingface dataset:
Show your sources. The studies that indicate it’s not effective are in comparison to a placebo when alcohol is NOT consumed with the drug. The Sinclair method is very specific about taking the drug with alcohol (and measuring its reduced usage over time).

To my knowledge liver damage has only been documented at doses far beyond what the Sinclair method directs.

Edit: source as requested below: https://academic.oup.com/alcalc/article/36/1/2/137995
Doesn't Spanner support ACID transactions?

(Disclosure: I work for Google)
i can forgive the reporter for making a clickbait title, but atleast give the news some time to rest and get all the facts . from the brief info provided in the article only thing clear is that the driver was in the car when the accident occured and that some agency is investigating the "accident" and not the manufacturing units of the company , two very different things. minor aside here it would behove media organizations to disclose the short or long positions they have on any company they are reporting on.
The Government's Anti-Opioid Crusade Is Getting People Killed
"We need to invade lots of countries, remove the dictators and then all things will be great"

Yeah, no, please don't. Don't create the next Libya in 2019, just because you need to make place to buy new bombs.
And the States do the same thing. shrug

Everyone is spying on eachother and we are not safe from that, despite what is said. I’m more afraid of the NSA having far reaching powers to spy on their own citizens than I am of China hacking into the NSA
So you're replacing one substance with another? How is that better?
> the need for a good general-purpose, efficient language

Is the implication that plain OCaml is not good?
Thoughts and prayers to his family!
> Is there a strategic advantage for a shoemaker to make their own hammer?

Sure. If they are paying $100M/y on hammers, it's at least worth running the numbers and investigate alternatives.
Depends how you define "stable". Is it "less likely to fall over" or "less wobble"? That's basically the difference here.

A 4 legged chair is much less likely to fall over because it has more points of contact with the ground (yes, this extrapolates). While you're correct that a 3 legged chair isn't going to wobble, many would call it less stable because it is more likely to fall over. The force is distributed only across 3 points and if you sit at an edge that force is going to be highly concentrated along two points. In fact, those two points are always going to create a lever. In a 4 legged chair there are many edges that you can sit on where the weight will be distributed to three points, you have to be specifically on the edge where two legs create a plane to distribute the force to 2 legs (see why this extrapolates? More legs and it is harder to distribute force to only 2 legs).

Why 4 though? Well, I don't have a scientific answer. But it is pretty well balanced, doesn't increase cost much, nor weight. So probably just a compromise. Though in a lot of rolling chairs you will see that they typically have more than 4 points of contact with the ground (notice how much harder it is to tip these over?).

tldr: 4 is actually more stable in the sense of "you're less likely to fall out of the chair and bonk your head".
San Francisco median one bedroom apartment rent hits a new peak of $3,690
You believe states have a right to free speech?
What do you mean? Everything you consume is a substance. Some substances are absolutely better than others.
Disclaimer: I’m one of the authors of the paper/blog post/code.

If you want to use signatures over the hash as proof of data set integrity, you need two things. 1) you need to make sure that hash({a}) + hash({b}) == hash({a, b}). 2) ensure that hash() is collision resistant - in other words, it needs to be computationally infeasible to find hash(S) == hash(T), S != T for any sets S and T. We prove that LtHash with our choice of parameters has this property in the paper (which is linked from the blog post).
If whiteboard job interviews with clever algorithm problems are so bad, how is it that successful companies like Amazon and Google do it and they are both hugely successful?
For those saying a GC is too high level, malloc is also a high level abstraction. There are relatively simple implementations of malloc, but allocators like jemalloc are starting to look quite a lot like a GC in the ways they manage memory.

The real issue with GCs is the lack of control that makes it very difficult if not impossible to do things like grouping allocations together. However, this capability comes at a cost since then you can’t move around existing allocations without going to extreme lengths and can easily lead to memory fragmentation.
Important to note that for many of their launches they weren't trying to land. They had 42 landing attempts, so over 80% success rate.
The reasons I choose not to use any pre-existing workflow are complexity and extra compute overhead. I think there's a need for micro workflow where it's simple enough you can setup a simple production workflow in a single python script without requiring a ton of heavy package. d6tflow seems light enough for me, using luigi and two dataframe libraries.
On the face of it, I supposed it depends on the relative downsides of the two substances.
Isn’t this stance completely dismissive of methadone clinics approach to addiction? If the individual can break a stronger and more dangerous addiction with a less addictive and dangerous substance then it’s a net positive on their addiction journey but not the final stop.
I'd encourage you to read this tweet[0] and this article[1]. They provide perspectives from Saudi women. To do my best to summarize:

Indeed, the app is bad. That it exists or needs to exist is a bad thing. But given the Saudi government and Saudi law, the opinion of many women in Saudi Arabia is that scrapping the app would hurt their agency, not help it. They need male approval to travel either way, and by making it easier to get, the app, in practice, gives women more agency by lowering the bureaucratic barriers to travel.

The best way I can put it is that the app here doesn't really particularly help the oppressors. Like maybe, in a contrived way, you can argue that by making the oppression lighter weight you're less likely to have a full on revolution or something. But then, you've still lessened the oppression. That's not a bad thing.

But if removing the app from the store makes the experience of women in Saudi Arabia worse, which is exactly what many of those women are saying, then removing it doesn't do anything. You're just asking to have the Saudi society regress even further to a position where in practice women had even less agency.

Is that better?

[0]: https://twitter.com/monaeltahawy/status/1095360734798721025 an

[1]: http://time.com/5532221/absher-saudi-arabia-what-to-know/
Statistically, in the 30s, suicide and drugs (addiction or overdose) are the top 2. Car accidents is next.

Extreme sports and motorcycle accidents apply to such a smaller percentage of the population.
I sincerely hope you’re kidding and the people who replied positively are your fake accounts.

By doing that, you’re app will be almost immediately blocked, hopefully banned, and likely also the user accounts banned.

The right way to do it is using fb api under its limitations. In addition, if I recall correctly, you’ll need to refresh user’s token every 30d, so you prob want an excuse for your users to come back to your site frequently, e.g. via an email that shows weekly stats.
Price in the cost of all future security updates? Why would I want to buy software updates for life? That sounds incredibly expensive. And if a company were successful at selling this model, they could be taken over by some greedy businessmen who cut costs in order to get short term profit.
I am proud to say my company has a phone screen coding question 100% relevant to the day-to-day work you do. And also all our coding / whiteboarding / behavioral questions are geared to answer if you know how to handle challenges that daily life in the company will bring, and what sort of person you are.

To come up with the right questions was a difficult effort. We definitely avoid algo / puzzle questions like the plague, and the technical stuff we ask is more of a discussion than a quiz.

So yeah, it is important to look for the right signals.
UnityScript and Boo are deprecated and most people strongly discourage from using it.
In the case of housing and transport, it's easy to see why prices can be very different in different parts of the world: cheaper housing basically just means that not as many people (relative to the number of houses available) are willing and able to spend a lot of money to live in that location; transport prices probably differ for a bunch of reasons, but the main point is that there's no reason they should converge, as transport within city X is not a possible substitute for transport within city y.

For other goods, you should be surprised if the price discrepancy is one that you really could exploit for significant profit (after accounting for shipping, import/export restrictions and taxes, and so on) -- but otherwise, I don't think it's a very strange phenomenon. Prices will always be set somewhere in the overlapping region between the cost of production (and distribution, and taxes, minus any subsidies, etc.) and the amount that customers are willing and able to pay. Both of those amounts can vary pretty dramatically from place to place.
Are you sure? I suspect that they’re the people most likely to participate in those polls.

I personally can’t be bothered with these kinds of questions, but I remember that back in my early days, I was something of a zealot when it came to things I knew vs things I didn’t. I cut my teeth on PHP, MySQL and Flash/Actionscript. Had you asked me back then how I rated those things, I’d have given them 10/10, despite having nothing to compare them to.
It's interesting that you use the words "dangerous" and "this kind of drug" for a drug that is the antithesis of the opioid epidemic.

If you're worried about liver damage please look into Acetaminophen.
"No word genders in Finnish, sorry!"

No direct word for "please" either, unless you want to count kiitos, which I understand as thank you.
Isn't the simplest explanation that agrees with the evidence that he just died?
> This person can still get a job somewhere else.

You don't know more about the person's situation than the person himself.

> He can still go visit his family wherever they are.

As long as "wherever they are" means "somewhere he can go by foot".

> The government isn’t stopping him from living his life just because of some “social score”.

No, the invisible hand of the market is stopping him from living his life because of his negative "money score".
LSD is not physically toxic the way alcohol can be when taken in excess.

Furthermore, this is more of a matter of opinion but I strongly feel it doesn’t dull your senses / decision making / cognition the way alcohol does.
Yes definitely go to your doctor or see a psychiatrist before ordering medication online. There are alternatives like Baclofen or Gabapentin, moreover there could be other underlying issues that need to be treated. Self medication is not a solution.
Perhaps we have different interpretations of those quotes, but I think they reinforce my point, which is that they take a “rules are rules” approach rather than thinking of if the rules actually make sense.
I mean, Elisp isn’t the greatest as languages go, but it’s really nice actually (compared to all the other languages that you use to script editors). The joke that everyone makes about emacs is “it’s an operating system with
an editor on top” is actually 100% true. Emacs is built on top of Elisp, which is a testement to it’s power.

From your comment, it sounds like you’ve never used emacs/elisp. Why don’t you give it a try? With evil-mode, you don’t even have to give up your vim keybindings! Emacs is the most configurable and powerful editor in existence, and that’s not an opinion, it’s a fact.

PS: I actually use Intellij for my day to day scala work, but emacs is still the best (given enough time to configure/program the way you want).
How many people have died from LSD? Surely some addictions are better than others. If he had replaced his alcohol addiction with chocolate wouldn't that have been better?
Understanding Tariffs and Your Wallet
Flashpoint | Software Engineer | New York, REMOTE | Full-Time, Interns | Python

Flashpoint provides meaningful intelligence that enables large enterprises and the public sector to bolster cybersecurity, confront fraud, combat insider threats, enhance physical security, and address vendor risk and supply chain integrity. Flashpoint accomplishes this through integration of collections systems and a streaming data pipeline with an intelligence analysis team.

Flashpoint Engineering hires for empathetic and force multiplying individuals, and assesses candidates through a take-home test, code review, and structured interviews.

Software Engineer #1 job description: https://boards.greenhouse.io/flashpoint/jobs/4077118002?gh_j...

Software Engineer #2 job description: https://boards.greenhouse.io/flashpoint/jobs/4212896002?gh_j...
The article mentions this itself, but I think it's still worth mentioning that carbon scrubbing is hard to scale. IMO it's still better to work towards cutting emissions and finding sources of clean energy: in a very extreme case, assuming we can figure out how to get unlimited clean energy from fission/fusion/pushing baryons into the seventh dimension we can just pull CO₂ from the atmosphere and split it. Many of our problems can be solved with unlimited energy; clean water for example (just boil it!).
Parasites are good for you as they feed on dead, damaged cells. They're the quickest method of detoxification. The best thing to do when you have a parasite is to let it run its course while eating plenty of raw eggs and fat.

Source: Aajonus Vonderplanitz, We Want To Live and The Recipe For Living Without Disease
You would either take one or two high levels and stop both or a low level lsd over a few months and then stop both.

Reminds me of antibiotics. Kill some over connected pathways vs Kill some bacteria.
Men are only favourites by 1-2%. That's within the margin if error. Women are favourites by say 10% plus. The comment treats them the same, and base their theory on a binary concept. It's just bad logic and may even be a version of the Simpson paradox.
Like Xerox?

https://books.google.ca/books?id=KIEIX2X-na8C&pg=PA68&lpg=PA...
I agree that Naltrexone can help curb alcohol use in the case of heavy/problem drinkers, but alcoholism/addiction is entirely different than "developing a taste".

For anyone who is struggling with addiction, or thinks they may have a problem - please treat this like any other disease and consult a medical professional.

I'd also suggest, if possible, speaking with another addict in recovery to learn about what they have found successful. There are 12 step support groups (AA and NA being the two most well known) worldwide.

There are many available treatments and it's really difficult to know what will be best for any one person (and what works for an individual at any given point in time may change).

(Also, if you have been actively using alcohol or benzodiazepines, please consider talking to medical professional before abruptly stopping - there are serious risks during withdrawal and it can be deadly).

If anyone need help finding more information, don't hesitate to message me.
Naltrexone is generally safe for most, but in severe cases of cirrhosis it's not recommended. There are alternatives, but someone with that level of alcoholism usually needs to be clinically monitored.
That’s the whole point of doubly robust models. However, in the event of confounding by indication or sampling misspecification, my experience is that nothing can save you.

I am a rather strong proponent of randomized trials for this exact reason. (They can also have sampling bias, but some degree of noise is inevitable)
The short description of the study in the link indicates 4x4 minute intervals at 85-95 percent with rest between sets which seems more like VO2Max intervals than HIIT and is described as High Intensity Interval Exercise, your description is closer to ballpark what I know of as HIIT, sometimes called Tabata intervals, which definitely need a warmup that depends upon you but 20-30 minutes is the minimum I strive for.
I feel like you're missing something if you object to a treatment for alcoholism on the grounds that the treatment might cause liver damage. Alcoholism definitely will cause liver damage.
Came here to say this. Simpson’s paradox is exactly how gerrymandering works. It’s all about how the data is grouped.
Show HN: P2PSC, a fairly secure P2P chat service
The Sinclair method faces a lot of institutional incentive-related difficulties (generic drug, permanent treatment). It also has some aspects that are counterintuitive at first glance (e.g. it requires drinking alcohol, which creates skepticism when proposed by an alcoholic) but which are scientifically grounded. To anyone facing the problem of alcoholism: please do take the time to research it, read the studies, and form your own opinion. It’s really worth the time, and it’s not something you’re likely to hear about through traditional sources (yet) for the aforementioned reasons.
All it needs to work is a field for a URL template, and for the archive system to have sane URLs. Pipermail URLs don’t correspond to anything in the email, so the simplest imaginable integration would entail an additional entry point like /lookup?list-id={listId}&message-id={messageId} which would redirect you to the page for the right email.

Granted, this is really bad when compared with an integrated archive, but it makes it at least possible. You could easily then go on from there to automatic configuration for specific archive systems.
Does C# have multiple dispatch ala CLOS?
Shut up with your crap and Just write.
Even Jesus drank wine
So, I made a point to point chat program as a side project... it's fairly secure and is super minimalistic and easy to use. I'd appreciate any comments.
Lol, TLDR;
If you are a startup break every law, agreement, and regulation you can.
I'm not quite sure I follow your complaint, but I think I might be disagreeing with you. A key lesson of Simpson's Paradox is you can't read stories into data without having a causal model derived from outside the data.

I can comfortably invent stories that are not inconsistent with the data for a wide range of scenarios:

1) Only the most capable women are applying to Dept A due to discrimination, so the data is evidence of discrimination.

2) Dept A is discriminating towards women (self evident, 80% vs 60% admissions).

3) Dept A is completely non-discriminatory and the assessors are unaware of the gender of applicants; the differences are due to personal choices w.r.t. education and social networks turning out to be proxies for gender.

No study this sort of data can detect gender bias. It can be used as evidence in a broader study that comes up with a causal model for how the admissions process works; but there is no getting around interviews and field observations.
Washed up right by here; it caused quite a stir. It wasn't the only one, either: another one had washed up a mile or so west, though I don't think it was a hoodwinker.
Nope. Please explain what point you are trying to make. None gets it
The smarter you are the more you would understand this and smarter people would be happier.

The happiest people don't worry and find joy in the things around them.
I miss the days when nessus was good enough to justify being cool.

Then again my favorite bug back in the day was veritas backup acting as a reverse shell. I only learned of that by running nessus.
The first time I ever did a “keg stand” in my life was not in college, but in my late 30s one week after joining a startup which had kegs in the office.
I still do not understand. How are men "favourites by 1%-2%" and women "by 10% plus"? Favourites, for what?

And how did you calculate the margin of error for this study?
If anybody else is wondering how to navigate that, you need to mouseover the right image to get an arrow, then click to advance. (Because scrolling vertically would be just too obvious.)

There are also additional pages of pics under the +Portfolio dropdown.
And Canada now has zero credibility here. Between a US created diplomatic crisis with China and our Liberal government being exposed by it's on Attorney General, China has been proven right. Our courts are still at the control of our corrupt PMO.
https://nationalpost.com/news/politics/the-tories-passed-a-m...

US/Canada human rights arguments arguments are pretty galling by a NA Aboriginal POV.

I think the protester in Tianemen square had more of a chance than the students in Kent State.

Kettle And pot are black as night.
"Works from my machine." Check out the results of https://www.whatsmydns.net/#A/archive.is
Ironically, it's being curious on how to break something or how something that is for "A" can be used for "XYZ."

Though what you hear about more often are misconfigurations -- which, are valid, but that's more on execution vs truly finding something wrong.
It’s not entirely fair to call it a black box but I do totally get what you’re saying. Debugging involves stitching together logs from the api-server, kube-proxy, scheduler, and kubelet itself.

You also have to be extremely careful with your affinity / anti affinity rules. The interactions get realy complicated really fast.
Merkel’s Power Conundrum
Does this go for all parasites, or only certain parasites? Is there data on that? Intuition and quick Google tells me that may have to be careful about which parasites you "ignore".
No, but realistically it's not very accessible (general-purpose). If people go for OCaml that's great, it's an amazing language and it's obviously the same language. But the ReasonML focus has been on developer experience and it's showing.
> Quadriga’s platform data is stored on the cloud with Amazon.com’s Amazon Web Services, or AWS. While Jennifer Robertson, Cotten’s widow, has asked for access to the data, she has been denied because it was in his name rather than registered under the company. Ernst & Young has requested the court grant an order authorizing access.

...is she not his heir? What's happening there?
Sadly once you are older it starts to make more sense.
7-minute workout is mostly a myth. You can do a very intense and thorough workout using the 7-minute routine but all the reported benefits involve working yourself up to 3 repetitions of the 7-minute routine so it really takes 21 minutes.
How the N.Y. Public Library Fills Its Shelves
Or weed/cbd.
No, it has single dispatch virtual methods, a la C++.
Rental housing is a market and just like other markets it can be modelled using the economics described by the demand curve.

The demand curve maps the relationship between supply, demand and price.

It says that for high demand and low supply the price is high, for low demand and high supply the price is low and over time supply, demand and price will find an equilibrium.

So if you consider the housing market, on the supply side you are looking at a constrained resource (i.e. it is constrained by the land available to build).

The demand side will be driven by the numbers of people looking to rent and that will be driven by many other factors like work prospects, quality of life, crime rates etc etc.

So for places like SF there will be great demand for that limited housing which means the price (i.e. the rent) goes up.
There are few facts to make the case in either direction, so the anecdotes are valuable.

Of course it's a bit of a shame that the one comment not subject to HN groupthink is [predictably] all the way at the bottom of the page.
For tables: leg room and leg exposure.
Yes there are many unethical physicians, but majority of physicians still are hard-workers and know way better than you.