skysight-inc/HackerNews huggingface dataset:
It's slightly worrying the language from pharma is very similar to the early opiod days.

"The voice of the pain patient is underrepresented! We should approve opioids"

Now is

"The voice of the depressed patient is underrepresented! We should approve nasal ketamine".

I'm all for new therapies but ketamine can be highly addictive and causes really nasty side effects in high quantities (bladder problems being horrific from what I've heard). I hope we don't see a huge spike in ketamine abuse in 10 years time like what happened after overprescription of opioids.

I also think this will be extremely popular. Current antidepressants are not very effective and take a long time to work. This seems to work very quickly. Who would want to wait 8 weeks Vs hours to get better? It would not surprise me if J&J have massively downplayed the potential addiction risk of this.
The standard download of Vue.js is 95k; React is 120k.

I have no idea where you got your "500%" from, but it seems wildly off-mark.
> We demand that BuzzFeed News recognizes our union immediately so that we can swiftly reach a mutually satisfying contract that lets us focus on the important work of reporting on Cardi B memes and breaking the biggest stories in the country.

So it’s a joke right? I... can’t even tell.
Does it matter what it serves considering it's written in something completely different and the output is generated by a server not a human?
I don't think it's that easy to find someone in witness protection, unless there are some other sloppy programs in the US, you, sir, are incorrect.

"More than 18,400 men, women and children have participated in it, and not one of the 8,500 witnesses or the 9,900 family members has been harmed" [1]

Now his family idk, good luck to them.

1. https://www.cnn.com/2013/02/16/justice/witness-protection-pr...
Maybe they should figure out the whole thing before spending billions.
Don't forget that Japanese politicians are addicted to public works spending and have been for generations. Great infrastructure is nice, but is it worth having a public debt that is 260% of GDP? Japan's population is also shrinking so a lot of the infrastructure will be fallow in the future. Both the USA and Japan have political problems with infrastructure procurement, just in completely different ways.
It seems that construction companies have learned from the medical industry how to be f...ing expensive.
It's standard operating procedure. Declare success even as you're winding it down.
Did you even read the opinion presented in the article you posted? I don’t think it’s quite the comeback the tone of your post would suggest. The two camps seem to break down in terms of “signaling” or “sending a message”, and the argument I represented which is grounded in the evidence. For spice we have the person pointing out that in fact these burns/crushes present a ripe opportunity to steal the ivory.

In some corrupt countries, ivory burns and crushes can act as a way to steal ivory because it is not all carefully recorded in its destruction. Although initially these acts made a statement as a cry for help, such as with the first Kenya burn in 1989 that helped put ivory out of fashion in the U.S. and Europe, many in Asia find destruction to be against their culture and think the ivory could be used for making an artistic monument as a long-term statement instead. It is the Asians, especially the Chinese, whose viewpoints on this issue count the most, as they are the main consumers of ivory. Ivory crushes can detract from what is really needed to save elephants: much greater efforts on law enforcement and improving ways to protect elephants in their natural habitat.

Experts clearly disagree, but I find arguments about sending messages or deterrence unconvincing, as they tend to come from the gut rather than the evidence. It’s just that kind of sloppy thinking that death penalty advocates often use when confronted with evidence as well.
The RDF world has conclusively proven that there is more than "One Graph". (e.g. people try to make "One Graph" and their projects die; try to make as many graphs as there are points of view and the sailing is smooth)
I think that's great. That said, I've tried audio (books) and it's just not the same as reading (print). Reading, to me, seems to engage the mind in a deeper way. It is, nearly by its nature, more proactive and participatory. On the other hand, watching and listening is far more passive. You don't work to consume, you just wait for it to come to you.

For example, when you read you can pause, re-read, etc. On the other hand, who watches the news (for example) and uses pause and/or 30 second rewind? Not to get off topic but my personal theory is this is why journalism today is so shoddy - because it can be. It's just an endless stream and no one is pausing long enough to say "Hey! Wait a minute!!"
Right. It will be cheaper per mile with a larger project.
Stop electing Republicans and Democrats would be a start.
Also, we literally __voted__ for the project.
Ketamine is an approved drug that we use in clinical practice.
Your "memory palace" could simply be a row of doors where different sounds come from each one.

Or a jungle where you have to crawl and climb over obstacles to move around.

Imagination isn't just visual. Just because you can't "picture" something in your head doesn't mean you have no imagination.
Dialogflow, wit.ai, amazon lex, Microsoft language work well.
I did not know King was owned by Activision/Blizzard [1]. I wonder if/how it will affect the development of the Defold engine [2].

1: https://en.wikipedia.org/wiki/King_(company)

2: https://www.defold.com/
Macro security stories distract firms from real problems
> it's to work on reducing the cost of writing correct software while acknowledging that the average dev is well average

Absolutely agreed.

I wrote the above because I'm frustrated by how often these conversations lead to either calls for more diligence by individual programmers (who are both average and likely working in broken systems), or draconian oversight approaches that amount to treating website developers as though they're designing bridges.

The really interesting things in this domain aren't attempts to force programmers to do a better job, but to make doing a better job easier. It's stuff like Rust attempting to break new ground in safe-by-default memory management, or Let’s Encrypt lowering the bar to getting set up with TLS. Oauth has some downsides, but it's certainly helped move us away from a world where every random site makes its own sloppy attempt to manage user auth. For that matter, IDEs deserve credit for reacting to common classes of mistake; defining a local variable then operating on the input instead is the sort of thing that's easier to catch with an automated warning than with diligence or even tests.

This sort of change has already taken web reliability from "sketchy at best" to "surprisingly good"; common hosts like AWS make basic load balancing and scaling straightforward, and CDNs and DDoS mitigation have become increasingly standard. We're not going to be free of bugs anytime soon, but I think there's good reason to expect actual progress.
Bootstrap sets a solid foundation for enterprise projects, where there are often many disparate projects, many developers, many deadlines, more concern with function vs. style/brand.

"because that is what they know and don’t bother picking up the new standards"

That's just an unnecessary comment and plain wrong.
It's okay, they didn't get fired; they're just being scaled down!
If this was the case then populations wouldn't be expanding - too many people would be dying before reaching reproductive age.

Its simpler than that. Women in many parts of the world have no agency, and no access to contraception. Change those two things (this should be the REAL battle of feminists) and you will go a long way to solving overpopulation.
Same goes with me actually. I'm not entirely sure but I think most of it is attributed to the huge amount of optimisations and refinements that have gone into the modern mobile GPU's. While the mobiles don't seem to be quite as diverse in their capability, they excel at what they can do!

The future is a strange place.
Not approved to treat depression.
Taiwan is effectively China the went down the capitalist path a few decades before China itself. Taiwan's engineers now lead the pack in what must be one of the the most punishing technology areas - semiconductor manufacturing. In less punishing areas mainland China leads the world in manufacturing. Yes, part of that is to do with having cheap labour, but you don't get to be the best at the world at anything by sitting on your hands. Every time someone business figures out how to build something cheaper than anyone else on the planet they have been innovating, and China has done this many, many times.

What is different about China is an attitude. It was crystallised for me by a Australian Documentary titled "Two Men in China". One of those men was formerly Australia's chief scientist. They walked into a typical Chinese apartment. Very small, but it had all the latest gadgets. Then they showed the doors had fallen off some cupboards. In fact a whole pile of things had broken a few weeks after the couple had moved in. This was considered perfectly normal - they even had a word for it (which I forget).

In extreme cases it leads to things like baby formula suppliers adding melamine (a poison) to get the protein readings up to spec. (Australia's baby formula industry has done very well out of that little episode, so well there fights in the baby food isles appears on the nightly TV news as Chinese expats empty the shelves to make a quick buck. Turns out that _really_ pisses of local mothers with a hungry baby in their arms.) If you read stories on HN you come to the conclusion this attitude must pervade the entire business culture. Building falling down because of sub-par concrete, stories of "we sent them a spec, they built it well for a while, then someone notices part X had been replaced by a cheaper version" is a very common thread. Anybody who does business in China has to spend an inordinate any of money verifying all their suppliers are not cutting corners.

Americans are coming face to face with this now Amazon has allow the Chinese suppliers unrestricted access. Fake products, fake reviews, fake suppliers, fake purchases on other products leading to critical reviews, bribes for fake reviews - any scam that might work even only for a short term is being tried. Now imagine living in the country where that is how all business is done. Is it is at all surprising someone bought a system with face recognition, only to discover later it could be fooled by a photo?

If you are thinking China can't innovate you are just plain wrong. If you are pinning your hopes they will be perpetually held back by corruption you might be right (things look bleak under the current leadership) - but it's also possible they could turn into another Taiwan or South Korea, albeit with 1.3 billion people. If that happens we will see innovation on a scale we have never seen before.
In my experience younger voters are more likely to vote for "give me free everything" which drives up the debt.
Gates Foundation annual letter
> You are being obstinate. I cited a couple extensive discussions of the matter backed by voluminous scholarly work

Hm? Sorry, I think I missed them. I can only see two videos of Noam Chomsky.

> and they are essentially a client state of the U.S

This is what you are trying to prove. I haven't heard a single argument or seen a single good reference yet.
Public money? The government spends enormous amounts of money on medicine and medical research. Just the government’s own savings (Medicare and otherwise) from the availability of better inexpensive drugs could pay for the necessary studies.
Planet Money did an episode on this subject in 2017:

https://www.npr.org/sections/money/2017/10/04/555646290/epis...
Steel tariffs will probably have some pretty wide-ranging effects that I don't think we've totally seen yet.
$77b buys 10 nuclear plants and does far better good at reducing carbon emissions. You'd want nuclear to power those trains anyway.
King shuts down former Z2Live mobile game studio in Seattle, cuts 78 jobs
> A thing I always didn't like of Bootstrap is that it requires you to load a full version of jQuery just to use it.

You can just use the CSS and ignore the JavaScript parts, or write your own JS to build the CSS, which is what I did (twice, at the different jobs).

I never liked the Bootstrap JavaScript for a host of reasons. Unfortunately this incompatible rewrite fixes exactly nothing of that.
Psychedelic is the correct term.
Because I'm on a Mac and wouldn't be able to test it. :-D

Patches accepted here: https://github.com/irskep/keplverse

I also blogged about the algorithm, if that's of interest: https://blog.steveasleep.com/using-data-from-the-kepler-miss...
It's one thing to release a security patch. It's a different thing to get it installed on user devices. If a user never has an opportunity to install the patch, that patch might as well not exist from that user's standpoint.
Now we will see the destructive effect, when well paid people use thuggery tactics to try and force higher wages, for less work, AND pay union dues.
Soon the bell will toll for Buzzfeed Canada
From this article
https://www.upi.com/Top_News/US/2019/01/09/El-Chapo-jurors-r...

"FBI Agent Steven Marston said the agency obtained warrants to intercept hundreds of text messages from 2012 via the spyware Guzman installed on the phones of his wife Emma Coronel Aispuro, associates and purported mistress Augustina Cabanillas Acosta, The Los Angeles Times reported."
> When will enough be enough?

https://www.gameworkersunite.org/
it's the golden rule: would you want this app used against you? if not, then it should be taken down.
> One less dependency, network request and more efficient code is always worth the effort.

Except that 90% of sites that use BS5 will continue to use JQ for other things anyway so, in reality, you won't have less code, fewer requests, etc.

Personally I've felt for a while that JQ's day in the sun is over and that developers should really think about whether they need it or not. Maybe really getting rid of it starts with slightly risky moves like this. Like when Apple killed the floppy.
The road and bridge infrastructure in this state is completely falling apart. The water infrastructure was built for a population half or a third of what exists currently, during the Pat Brown era. Calpers has half a trillion $$ in unfunded liabilities, which the younger generation---many of which still live with their parents---is supposed to pay for.

And the Democrats chose to spend $100 billion on an effing train to nowhere.
VFEmail says all US-based data is gone
This doesn't really matter--off-label prescriptions are extremely common and don't seem to be strictly regulated.
Lighting $10 on fire is a lot better than spending $100 and getting $50 back. You take a bigger net loss with the latter move.
Ecstasy is a stimulant, not a hallucinogen.

It’s both.

Ecstasy/MDMA. MDMA (3-4 methylenedioxymethamphetamine) is a synthetic, psychoactive drug chemically similar to the stimulant methamphetamine and the hallucinogen mescaline.

https://www.sciencedirect.com/topics/neuroscience/mdma

I thought bloomberg was generally considered to be better at fact checking than that.

They are. You’re not.

The use and abuse of MDMA (3,4-methylenedioxymethamphetamine, or ecstasy) is a significant public health concern. In the United States, MDMA is classified as a hallucinogen, a category comprising LSD (lysergic acid diethylamide), PCP (phencyclidine, or angel dust), peyote, mescaline, and psilocybin (mushrooms).

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2648386/#S1titl...
This is really effective! Nice work. Indeed though there are some astonishing capabilities for the web out there now.
You cannot do syscalls, but you can read/write all memory, which means you can make some arbitrary (trusted) process your victim, executing code in a ROP manner and antivirus won't see a thing.
>I love how in proper Christianity

One common thing religious people tend to share is that they all think their own interpretation of their religion is the right one. Is there any reason to believe your use of "proper christianity" here is any different from that?

Besides that, though, I found your comment about how christianity makes the assumption that everyone is utterly, hopelessly depraved very good. I agree with you, but I haven't considered it in that way before.

I'm an ex-christian, because I've found I can't bring myself to believe in the supernatural, but I still see valuable things in the religion.

I don't think that you need to start off with the assumption that everyone is hopelessly depraved in order to have a non-judgemental society. I'm not even sure that's really desirable, or how that would work. But I definitely agree that we tend to be too judgemental and ego-driven.
> Side benefit: also no weird $(thing)[0] when you need to use a DOM API, like HTML5 validity or whatever.

But looping over querySelectorAll() is painful. I'm not really a frontend dev, so perhaps I'm doing it wrong, but this is the "easier" way I found when I was writing an app a few weeks ago (in TypeScript):

// Get Array of HTMLElements from querySelectorAll().
let queryAll = (q: string): HTMLElement[] => {
let nodes = document.querySelectorAll(q);

let arr: HTMLElement[] = [];
arr.length = nodes.length;

for (let i = 0; i < nodes.length; i++) {
if (!(nodes[i] instanceof HTMLElement)) {
arr.length--;
continue;
}

arr[i] = nodes[i] as HTMLElement;
}

return arr;
};
There's a great thread on Twitter that I can't find right now discussions some of the second order effects of layoffs like these:

* Game dev with family has to choose to either uproot family and leave area to find new job, or chooses to leave game dev and go get a job writing CRUD apps somewhere. Net result is loss of expertise - who's training the junior devs?

Remember, layoffs like these are common in the AAA game industry. I used to want to be a game developer, now I'm sad I didn't pursue it, but also thankful for the security of my "standard" software job.
Literally have a book in one hand and my phone to type this.
The comments here are full of the sunk cost fallacy. Which was clearly what the hsr creators were banking on when they decided to initially build hsr in the least useful part of the state.
I have being doing this for a while using Balsamiq Mockups 3.

The fact that everything is rendered as a low fidelity mock really helps avoid discussions like "move this 2 pixels to the left" or "maybe this blue should be more towards green". The exceptions are set in wireframe and when we have a working version is a nice surprise.
As long as one sells their property within 75 years, the investment functions the same as it does in the US. Each new buyer of a property gets a new 75-lease.

At least this is the way my wife (who is Chinese) explained it to me.
We're not limited by approved FDA indications, although we are (generally) limited by the standard of care. Granted, the current formulation is liquid and intended for IV or IM use (although there is academic literature on mixing ketamine into liquids for oral administration). The liquid part is the fundamental problem with using this off-label, in my opinion.
Mapbox is also in sf, with most of the company leadership based there (I used to work there)
I wonder if this will end up being the straw that breaks the camel's back and leads to unionization in the game industry. I've seen a decent uptick in serious discussion about it already this year after so many other dumb decisions by AAA publishers.

I know a lot of people here don't think there should be unions in software, but I think the game industry is a special case. There's enough starry eyed people that love the idea of working on games enough that they are willing to put up with total abuse and just about no one who cares about raising a family can seriously stay in that industry.

I myself spent a few years in it, and even though I love making games, it's just a serious hobby for me because I can't put up with the expected constant crunch, low salaries, and layoffs after every finished project.
Hey! If funding came our way we'd definitely look into it! Alas, the project's been put on a pretty indefinite hiatus. I'm starting to come around to the idea of just releasing all my unfinished things as open source projects, so maybe we'll end up doing the same with that one?

Glad you like the look of it though! Perhaps it'll start up again some day...
I almost loved this idea on the first sight, but on the second I'm not sure I see how it can work. Will you mandate Apple to make iOS installable on Huawei's devices? If not, why? If yes, how? Who will bear responsibility if SailfishOS won't run on Samsung's hardware? Do you really think API standard can be enshrined in the law, and how you plan to make it safe from corporate abuse?

Btw, if Microsoft is pushing security updates you did pay additional cost for license. If it's Debian then quite possibly you still paid something to MS (if your computer was bought with OEM version), or in better case other corporations, and individuals pay for it (mostly to reduce Microsoft's power).
I am in a similar predicament currently, and just want to let you know that there are others whom share your pain(s). I am 23 in 10 days, and haven't been in education since my community college days about 4 years ago. I have felt like a worthless pile of rubbish since then, however it is all related to depression, anxiety, ADHD, and an unsupportive family.

Personally, I find that small, but actionable changes to your routines and habits make the biggest difference. Please hang in there man!
That's the last straw. Cartels can send dangerous illegal drugs to people all over the world, hide the profits, murder people in the cruelest ways imaginable, corrupt the political system, abuse and exploit children -- but stifling science! I will not stand for that.
These massive compressed JS bundles make me think your numbers are off on the alleged golden age of modern frameworks:

https://webpagetest.org/result/190213_XH_63c61dc3d45cb95ec8a...

https://www.webpagetest.org/result/190213_NX_ee1e7ae8fa74557...

It’s not hard to beat jQuery in many cases but they’re looking pretty svelte in comparison:

https://webpagetest.org/result/190213_93_e2da91a07e2b2bc0234...
In the case of GraphQL, I'd be interested in seeing strategies for multiple graphs within a single codebase. Essentially being able to produce different schemas based on config. I know that superficially it's as simple as some "if" statements, but I'm curious about the maintenance/scalability side of it.
The ‘legacy’ airlines like American, Delta, United , Alaska, Hawaiian etc provide quite good disability programs. Additionally, ALPA, the pilots’ union, offers a loss of medical insurance. Often times a loss of medical is not something that was also debilitating. There are plenty of other jobs for airline pilots to do in training departments and other areas in flight operation requiring the same knowledge base.
> ban phones and cameras

Maybe this is just me being an "old timer", but one of my favorite aspects of burning man was getting away from connectivity and technology. There was no cell signal on the playa (or anywhere after Gerlach) and I could only send a text back from Center camp mid-week to let my SO know i made it.
The harsh environs also made it so that I didn't want to take a smartphone out on the playa.

The last couple of times I went (and I haven't been in 2 years), I was shocked to see that there was full 4G/LTE connectivity on the playa and that hanging out at a camp bar or mutant vehicle, you're likely to see the same face buried in their phones experience that you'd see in the default world.