skysight-inc/HackerNews huggingface dataset:
The Valeant fraud was 90% sketchy accounting and 10% price hikes, more Enron than Martin Shkreli.

By anyone's standard, they are not representative of the U.S. Pharma market as a whole.
hahaha at the very least I won't be surprised if podcast ads were a good chunk of their marketing budget. I only know about them because of the several different podcasts that do MeUndies ads.
The solar cell of the future
Define true, it is true that the US spends more on medical research than the rest of the world combined, and produces more drug patents than the rest of the world combined.

https://assets1b.milkeninstitute.org/assets/Publication/Rese...

This btw went up fairly recently especially since Indian generics became accepted world wide in the late 90’s and early 2000’s.

The US used to produce 20-30% of the world’s drug patents now its peaking at 60%.
Show HN: Prime Time – Countdown to next prime unix timestamp
The EpiPen is one of the "hard to manufacture" drugs I mentioned. Although it is top of mind to many, it is not representative of the market.

EDIT: "hard to manufacture" is in quotes because it's what I said in my parent comment (though to be fair I said "costly to manufacture"), but I meant it as an umbrella term for everything that can't be substituted by generics
Starting a non-profit research lab to help fix climate change ASAP
That example isn't trivial at all, because the reason he was blocked is ostensibly viewpoint-neutral: he was blocked for harassing reporters and using the platform as vehicle for doing so. You can disagree that that's what actually happened, and if the same thing happened to you you could sue your (I don't know) county supervisor over it, but given the clear evidence, you'll lose.

Twitter kept Alex Jones on the platform far longer than his insane viewpoints merited; they went out of their way not to block him.

Further, the way the platform is used matters. The county official in this case advertised her Facebook Page as a way to communicate with her about the job she was doing. If you don't promote your page (or Twitter account) as a public forum, but rather as either a personal profile or a broadcast medium, it mightn't much matter how you moderate.
It's all over the internet, so you should be complaining more about this being the next tier above blog spam rather than taking this as TechCrunch's journalism.

That being said, AT&T isn't currently shipping any 5G capable handsets, so a 5G logo popping up on any of their phones is arguably a lie. According to AT&T's stated intentions, they're rebranding LTE with most of the latest extensions as "5Ge" and real 5G will be branded "5G+". None of this is particularly hidden information.

Additionally, none of this is new, AT&T is known for faking this information, like displaying LTE when it might be able to see a tower that's LTE capable, but you're not able to connect to LTE.
All of msvc, gcc, clang, and the isocpp committee have active work ongoing for C++ modules.

We'll have them Soon™.
Using the pimpl pattern doesn't mean an indirect function call. The function to be called is always known. It's just an extra indirection in the data member. It's cheap. Think of it as Java style memory layout: everything that's not primitive stored in an object is a reference and therefore behind one level of indirection. The performance of Java is acceptance in the vast majority of use cases. Using pimpl will be the same.
I love to the TDP # when 64 cores are running 2.6G.

Also like to know the L1, L2, L3 #.

It is hard for any system company to sell CPU. Apple is only for their own use. I believe the Samsung's AP is for their own use also.
Do you have any sources/data for this? I would be very curious to see it. The mentioned costs in this article only point to

> higher drug prices, higher salaries for doctors and nurses, higher hospital administration costs and higher prices for many medical services

I’m not sure if R&D costs are factored in at all for this particular study.
Given enough time, chains behind the lead position will always succumb to this attack vector. Ethereum's design was flawed in other ways, but at least now it's clearly best used as the sandbox that it is.
I don't know about Epipen, but it can cost billions to bring new drugs to market https://cen.acs.org/articles/92/web/2014/11/Tufts-Study-Find...
you may not be aware but your comment came off as somewhat condescending, given that you don't really have any idea where parent poster is coming from or what their background is
Not that anyone cares, but last time Sprint/Clearwire 4G WiMax was 4 Mbps while AT&T/T-Mobile 3G HSPA was faster than 4 Mbps, giving Sprint an unfair marketing advantage. Labeling HSPA as "4G" reduced customer confusion in some sense.
The soccer and piano practice is to get into Harvard.
On my MBPs (2017 and 2015 models) battery life length takes a very heavy hit from Chrome and Chromium-based apps as well as from Firefox. Running native apps only alongside Safari I get great life, but if I have to open Chrome, Spotify, etc battery gets chewed through like crazy.
I'm not sure you would have been better off being raised how your parent (hah!) poster described, as you kind of allude to in your last paragraph yourself. Maybe your parents were too laissez-faire and too lenient in how they treated your missteps, but I don't think that means that parents should take control over their children's free time and force activities upon them. You say that you would have preferred your current life over "street smarts", but I'm not sure how the parent poster's style would actually provide that, instead of just depraving children of organic, free-willed social interaction.
This is not the first time AT&T has pretended to have a newer network than their infrastructure actually provides.

https://slate.com/technology/2012/03/4g-vs-3g-beware-of-the-...
I mean, "5G Evolution" is an AT&T specific trademark specifically designed to mislead consumers.
"IBM … in the ’70s … had made some progress on turning software into an engineering discipline. That essentially all got thrown away. The invasion of people [during the personal computer revolution] … basically ignored everything that came before them."
Announcing OneDev – open source Git server with unique features
Sure, but aren’t those extremely niche use cases? How is that innovation?
Here's an article from 2 weeks ago, with a much larger discussion and the evidence you're asking for. Not sure how this current article is better than the older one. https://news.ycombinator.com/item?id=18736378
You are aware that Ethereum Classic is not the same as the much, much higher-hashpower Ethereum chain, right?
Its like we are engineering super workers for modern society. At some point, human happiness really needs to come up over trying to maximize production.
I don't understand. We all define non-acceptable non-criminal behavior all the time.
Bitbucket has had free private repos for the longest time. Any compelling reason to move small private projects to GitHub?
I would advise against that, I tried to dabble with both platforms, but the markup at which those shares are sold is often incredibly high: common shares of most companies on those platforms are actually sold at prices higher than the preferred (crazy), even if such company just went through a very recent round of funding, meaning that the preferred price is pretty much the very top investors valued the company at.

I honestly don't know who would buy that, the idea I got by doing some basic due diligence on those deals is that who puts them online thinks "let's see if we can attract some dumb money to give us some liquidity at an insane premium". If you sell things at a fair price (e.g. selling common shares at the preferred price * 0.8, depending on the current stage of the company), investors will want to give you liquidity way before your offer on equityzen gets accepted and pollutes the cap table (I speak from direct experience), so what's left on those crowdsourced platforms is many times overpriced garbage.
Relevant: https://news.ycombinator.com/item?id=18157869

The linked article from before it was suspended: https://web.archive.org/web/20181007202929/https://medium.co...
"Again, I’m not arguing that Warren should necessarily become president. But she is what a serious policy intellectual looks and sounds like in 2019. And if our media can’t recognize that, we’re in big trouble." -Paul Krugman
Be wary of any healthcare mandate: it’s a device by which major health insurance carriers compel already poor people to sink money into overpriced plans that cover very little and come with numerous strings attached. Between high deductibles and mandatory coinsurance these plans are not coverage: they’re extortion.
The US spends more on biomedical R&D and produces more drug patents than the entirety of the world combined.

https://assets1b.milkeninstitute.org/assets/Publication/Rese...

As far as it’s implications on the cost of healthcare in the US I don’t think there is data for it since it’s pretty hard to measure.
That supposes that there is an actual definition of "5g" that anyone could be held to
What will be gender neutral about it? How will you account for the different body shapes of men and women?
Why should California tax payers provide health insurance to illegal immigrants?
Certainly return on capital investment is considered when deciding whether to invest in R&D.
it's supposed to be single payer, i.e. govt owned and negotiated rates should be lower than something like obamacare exchanges
15% year on year growth, year after year, is exponential.

Also - why do you keep saying Apple ‘expected more’?

It’s a multi billion dollar business and a growing hit.

You talk about hopes for growth that hasn’t come, but is that just an impression?
I don't know if it still the case but advertising costs were previously considered r&d so grossly inflating those numbers.
Like the article says, previous research has come to the same conclusion.

We pay much more, and are ranked nowhere near the top for lifespan, childhood mortality, and other measures.

Obamacare was a great first step. Define what basic healthcare is and form markets that encourage apples-to-apples comparison. Let the free market work.

Sucks that one party used this as a weapon to wrestle power.

Oh well.

Not going to argue here about healthcare reform, though. So if you disagree, don't expect a response.
> Do you have any sources/data for this?

Basically all equity research in the Pharma space backs up this view. Unfortunately I don't have any public data that I can share.
Everyone wants to blame drug prices but let's not ignore the problems of obesity, diabetes, etc. Much of which is a result of urban sprawl, poor diet (both in food culture, and in crop subsidies), and poor work culture.
For country of 317M people and 350M firearms those death numbers seem low.

For comparison:

33,700 people die in car accidents annually, that is 92 people each day.

8 kids under 15 die each day because of unintentional injuries (~3000 a year).
Another difference is that, with GitHub's announcement, there are multiple ways to interpret it because there are different things that the modifier "unlimited" could apply to. It could mean:

1. Unlimited number of repos, each of which is limited (by user, as it turns out).

2. Limited number of repos, each of which is unlimited.

3. Unlimited number of unlimited repos.

When there are multiple ways to interpret and you find out someone has picked one of them, it doesn't feel like they are being disingenuous.

Whereas with cell data plans, there's only one thing they could reasonably mean is unlimited: the data. So they've changed what "unlimited" means. It is limited, but there aren't overage charges.
There goes California's balanced budget.
Most technological breakthroughs are first perceived as toys and hobbies of the rich: personal computers, cellphones, mechanical carriages, Facebook. In this context, sour-grape reactionism is unfortunate but not surprising.

VR is where computation becomes human. No keyboards, no monitors, no mice or joysticks, but instead hands, gaze, movement, and voice. VR presents itself as a new way to receive information, but its essential innovation is data input in its most natural form.

Enabling humanity to engage with itself and its machines with a fully embodied interface is a 10x improvement over touch-screens. Small example: whiteboards. The simple act of a talented group viewing and marking a large flat surface can change the world. Today, this is not possible without co-location. Once a VR headset with positional and hand tracking hits the market (Oculus promises this spring), the rate of world-changing collaboration will no longer be restricted to geography. Once these virtual whiteboard trend toward Jupyter notebooks, VR will not only have triumphed over location-restricted bodies, but also location-restricted computers.

The future is bright and VR will be at the heart of it, regardless of how many people currently mistake it for a toy.
I think that with GitHub the "unlimited" is understood to mean "in repo count". You can create as many repos as you want and still get the same quality of service. You are not punished for creating more repos, you just have some limitations on (all) the repos you can create.

With cell phone data, "unlimited" is understood to mean "in quantity". However, once you reach a not-all-that-hard-to-hit threshold in that same metric, your quality of service degrades severely. I don't think anyone would have any issue if a carrier sold an "unlimited data" plan that provided that degraded quality of service from the start and didn't throttle based on actual usage. They would just factor the tradeoff into their purchasing decision and choose a plan appropriately. The problem is that the carriers advertise both the higher speed and the unlimited-ness when you can't actually have both at the same time.
because they provide services that you rely on and do jobs that legal migrants and citizens aren't going to do
> The test was performed by compiling the source code below 128 times, calculating the average time.

Presumably, 127/128 runs have both the test file and the single header file in memory cache, so the distinction is moot.

Also, I find the conclusion that we should all just buy top end machines and ignore performance problems that don't manifest there fairly unconvincing. I think that kind of thinking is responsible for a good chunk of the reason the web is so bloated today. :-)
It has 8 memory channels, the A12 has 2. So it's definitely targeted at a different segment.

The top of the line Intel Xeon has 6 memory channnels and the top of the line AMD Epyc has 8 channels.
If it was hard to manufacture, why is it cheaper in Europe?
Software still needs to be architected for performance from the start. Trying to micro optimize a loop before you know you need it what Knuth was saying to avoid.
I don't understand your point. Obviously it's going toward R&D of new drugs unrelated to the EpiPen. What does the price of an EpiPen have to do with how the money is spent?
This might be a naive comment, but isn't that predatory pricing. By dropping prices to zero and trying to purposely hurt your competitors, you effectively gain a monopoly on that industry.
As a U.S. immigrant who struggles to find truly healthy food choices in Manhattan of all places, I couldn't agree more.
You said this:

“Similarly, when one group pays more, others pay less. The state doesn't magically have more expenses.”

And that is absolutely false.

Also, there is certainly no relationship between raising taxes and the poor benefiting. The money can be wasted or spent on the military, etc.
Senior Full Stack Developer (Ruby, Rails, React, Node) Australia
At the same time, we are as close as we've ever been to human (or supra-human) spoken language parsing. Even if we have a ways to go on machine understanding / interpretation.

I can see (3D manual manipulation + verbal commands + weak-AI inference of intent) being a pretty compelling interface package.

For our primary coding purposes, I doubt we'll ever surpass keyboard.

But the counterargument would be that coding is a fairly esoteric set of criteria that we've specifically built around the keyboard (i.e. every character matters, no synonyms, etc). Were there an alternative... say, boilerplate code intelligently glued together by verbalized architecture directions? I wouldn't want to put a bet down. Rails convinced me that sometimes being smooth is more important than being best.
> Besides were using Typescript, have automated tests, code reviews and Manual QA, I'm not worried about the code not being solid or robust.

Oh god...

Yeah, no. None of this stuff is a substitute for actual code quality. Give me a good engineer that refuses to write tests over a mediocre one that does TDD any day.
Do you a source?

As far as I know, R&D never included advertising.
If you redirect the money both employees and employeers spend on healthcare- not necessarily.
Headphones Tech: Dynamic VS Planar Magnetic Drivers
As long as you meet the signal integrity standards, I don't think you majorly violate anything. So run one speed level slower than your cable normally supports and do some math on crosstalk per meter.
Because it's the compassionate thing to do?

Also because it's much cheaper.
Like the feature flag approach for all feature rollout(with or without schema change). If the flag is set the new feature kicks in so its easy to do a rollback if need be and we do this all the time. We don't close the feature ticket until the flag(old schema too) is removed and made as default in production after the smooth transition.
All else being equal, demand for a product increases when the prices of its complements decrease.

For the first time, developers can use GitHub for their private projects with up to three collaborators per repository for free.

The free repos are kind of a loss leader to bring in users onto the platform to keep Github as the de facto provider.

This is great news. I still prefer then issue management abilities of Gitlab nested projects, but choice and competition are good for the end user.
Maybe if we could pay citizens fair market price for their labor we wouldn't have to rely on illegal immigrants.
Is the fact that iPad has a touchscreen, unlike the Macbook a factor?
It's $250mil. CA is not gonna hurt from this in the slightest.
I think the line of reasoning is more that these social media companies could end up just doing the dirty work of banning/censoring the content themselves, and politicians for whom the site’s bias is advantageous would then flock there. One may also speculate that this could lead to backdoor corruption between social media companies and politicians.
It’s really quite ridiculous that neither WhatsApp or Signal have iPad support. The way their UIs are arranged, they could have iPad support for nearly free if they used UISplitView. There’s absolutely no excuse, especially in WhatsApp’s case.
Does helping individuals with their healthcare improve society? Presumably any advocate of government healthcare programs would say that it does. If it does, then why would the legal status of each individual affect the societal improvement?
In cell plans it's exactly the same thing though. The amount of data vs. the speed can each be artificially limited separately. They obviously mean the amount is unlimited whereas people somehow take it to mean both the amount and the speed are unlimited.
You would think quora learned their lesson about forcing uses to login just to browse the site after they got hacked. Apparently not.
I would like to see some hard numbers for this. Otherwise I believe this is just self-serving propaganda by drug manufacturers.
You need to be on campus for one week per module, then you have six weeks to complete your assignment, you need to complete ten modules to get the Master’s as well as attending a week long course on how to do a 15-20K word thesis based on project work.
> "California already covers undocumented children until they turn 19, with Newsom’s plan increasing the age cut-off to mirror that of the Affordable Care Act, which allows young adults to stay on a parent’s health insurance plan until turning 26."
The attacks tend to do something like "build a chain based off Dinkycoin's previous blocks, but don't publish it until a later date". The difficulty changes can't help because the chain doesn't know about the attack until the attacker publishes a longer chain.
Because the alternative is hospitals treating them anyway and sending out bills that will never get paid - ultimately costing society even more.

Unless you actually think illegal immigrants should just be left to die when they have medical issues? I sure hope not.
Good to know, but my question really has to do with if the extra cost for doctors, hospitals, drugs, etc. is used to offset R&D costs.

What I am getting at is that in theory, it should still be possible to do a lot of great R&D work while still providing affordable health care to citizens. I don’t think they are necessarily tied together.

Also more patents is not necessarily a good thing since they can create more legal hurdles and red tape for other pharmaceutical companies who may want to build on top of the ideas and inventions.
That's still technically lying; the network info that shows on the phone screen doesn't represent how fast the network is, just what protocol/network it's using. Consumers regarding `4g = faster than 3g` is solely due to how 4g was marketed.
Except the company that made EpiPen doesn't even make EpiPen anymore. Mylan bought the rights to make the drug in 2007, and then other companies bought it from Mylan. I forget who owns EpiPen now, but the current owner is very far removed from the original researchers who made that drug.
This could have been prevented with Komodo’s delayed Proof of Work (dPoW) Security for about $250.

dPoW explained here.
https://blog.komodoplatform.com/delayed-proof-of-work-explai...
That's not how it works. You invest if it's worth investing, not if you just have the money laying around.

Paying a few billion dollars to a big pharma company is not going to make them invest more in research. They will instead pay the money out as dividends.

The goal of patents is to create incentives for future research, but if you change the rules by increasing the extent of EpiPen patents after the drug was created, where is the incentive?
Far wose than average (mean).
Waiting for utf8doctor to cure 'em all
Unless it incentivizes more illegal immigration.
s/about/above
It would obviously be a huge proof of concept if you could make native apps on the iPad Pro, but I don't see why it's a crucial requirement for most developers to switch to an iPad Pro, since it would only affect iOS app developers.

For instance, I'd much rather have great ways to develop web applications on an iPad Pro.
Putin Claims His Hypersonic Missiles Are Invincible but He Jailed the Developers
how many citizens and legal migrants do you know are going to work in backbreaking conditions picking the food you eat for minimum wage? Cheap robots haven't caught up yet to pick and grow everything we need. Also note that not everyone can pay whole food prices
I did these kinds of tests in my early 20s (not sure how it would go now) and completely destroyed them. (I shut many many people up doing these tests, actually.)

> I barely ever can.
> It's not something I'll notice when listening for enjoyment.

Pretty much tell the story.
Sure, but that 12% isn't irrelevant, it's an investment. They're investing 12% of lost revenue in future growth.

Now, if personal accounts were far less (e.g. 1% of revenue), I could see the argument that they're irrelevant.

Maybe I'm just complaining about vocabulary, and perhaps your clarification was what the OP intended.