skysight-inc/HackerNews huggingface dataset:
As an attorney who does this type of thing, I can comment on a few of these things:

1) 1x-2x multiplier isn't offbase historically. Remember, though, that not every niche brand can be maintained on a part-time basis without touching stock or things like that. So, when one thinks of, say, a 2x multiplier, the calculus on the part of the selling company is much different than yours (i.e. they are selling to cash in and avoid further expense, effort, etc..., as well as hedging risk, of course, which presumably is a goal you share). But it doesn't necessarily impact the acquiror's calculus - depending on the type of buyer, they are going to fit your brand into their existing sales infrastructure. So, the effort and expense you incur doesn't matter to them quite as much as you would think.

In other words, you might not be able to reasonably expect a much greater multiplier because this business is so easily self-maintaining. Instead, it might just not make sense for you to sell.

Mind you, this is assuming the acquiror has an infrastructure your brand would fit into. Other types of buyers may feel quite differently and could pay a hefty premium for a business like yours. Finding that type of buyer is something I'm not sure how to do.

2) How these transactions are structured depends in a large part on the type of buyer. And there are a lot more structuring variables than all cash vs. financing.

3) Tax perspective? Not sure how you are structured right now. You may be able to qualify for QSB treatment, which would exempt much sale value from capital gains taxation. But I'm not sure you are structured now to allow that (or if you are an entity at all). There are way too many variables in terms of tax implications and you just need to make sure you have an experienced tax attorney (or accountant, if they have the right experience) looking at your proposed deal structure and working with the main attorney representing you.

4) In terms of the type of lawyer, an experienced corporate and commercial business attorney makes sense. This is not the size of deal that would be cost effective at a large firm. So, maybe I'm biased given what I do, but I think you'd be looking for a smaller firm that has business M&A experience. PLEASE make sure you go to an attorney before you sign a term sheet. You'll have a much harder time negotiating things if you haven't done so at the term sheet stage.

Hope this is helpful and happy to answer other questions.
From the SENS point of view [1] a number of the Hallmarks are downstream consequences of the causes of aging; e.g. epigenetic alterations are a reaction to molecular damage. Attempting to use those hallmarks as a place to intervene is doomed to achieve marginal benefits at best. You can't cure an age-related disease by patching over its late consequences.

Aging is a spreading tree of cause and consequence, emerging from a few root cause forms of damage. Intervene at later branchings in the tree, and you cover ever fewer downstream harms. It would be like trying to prevent a complicated iron sculpture from collapsing by propping up a few pieces here and there rather than by de-rusting/rustproofing the whole thing. Intervention as close to the root causes as possible is the only effective way forward, given how challenging it is achieve anything in medical biotechnology.

At the time the Hallmarks of Aging was published, it was noted for completely failing to reference any of the existing SENS literature, despite including some of the SENS line items such as senescent cell accumulation. The Hallmarks - and the related Seven Pillars of Aging [2] that seems to be less well promoted - would clearly not exist without more than a decade of aggressive advocacy within the scientific community for SENS and the treatment of aging, but the Hallmarks authors chose to behave as though that prior work never happened.

[1]: https://www.sens.org/research/introduction-to-sens-research

[2]: https://www.fightaging.org/archives/2014/11/the-seven-pillar...
Or they email you 3x a day for something you were interested in for no more than 10 minutes.
I'm thinking of the infeasibility of building a rocket to get off a large planet (compared to earth).

The intuition of a layperson is a bad guide, but I've always had the gut feeling that quantum error correction would prove to be exponentially difficult to scale. If smart people think otherwise, I can hope they're right, but I wouldn't bet money on it until I find an explanation I can grasp. It just sounds like a free lunch, or cold fusion.
The one thing that the article doesnt mention is how Boom is going to overcome fuel capacity issues traveling to Asia. Concorde was never intended for trans-Pacific flight. They're going to need to either create an aerial refueling system, or land somewhere.
(gross simplification below)

I've done a little research on caffeine, and as far as wakefulness goes (not touching the other effects here), it works by binding to the same protein receptors the body uses to decide if it is tired. Body unable to get signals that should trigger a feeling of tiredness == Body not conscious of being tired.

BUT the body responds by producing more of those receptors, making it more likely that it will start getting signals of fatigue even when the signaling proteins are at a low concentration. Thus, regular caffeine takers will find they need caffeine to feel a "normal" level of tired. It takes roughly 2 weeks without caffeine for a regular caffeine taker to achieve a no-caffeine level of such receptors.

Now, how much of the above is pseudo-science? Great question. FWIW, when I did the research the sources seemed credible enough (naming actual proteins, referring to actual studies, not just giving me animated drawings and hand-waving details) and it at least correlates with my anecdotal data - I don't use caffeinated drinks or supplements as a normal rule but do use them for special events (unusually late night/early morning) and have found the wakefulness effects to be effective unless I slip up and get too lax in my definition of "unusual". I also never thought caffeine was a big deal ( I never knew withdrawal symptoms, for example ) until I stopped using it as a general rule and my sleep improved notably. That said, my sleep quality is generally terrible so it doesn't take much to improve it.
overrated nonsense
Plus you get lab snacks if you go this route. If you order both from the US and European warehouses, you even get a wider variety of snacks.
I will probably burn all my virtual karma, but I just need to say this: I hated Catcher in the Rye with a passion. I used to do a lot of reading, still do my fair share, but just could not stand that book.
USA rocketry school tradition of counting engines by chambers makes R-7 a rocket which uses 32 engines at liftoff 4 main chambers for each of 4 RD-107 and 1 RD-108 (20 chambers) and 12 steering chambers (each with about 3 tons of thrust, about as much as a chamber of British Gamma-8 engine) - more than N-1. Yet R-7 is a pretty reliable rocket overall. Also Falcon Heavy has 27 engines, which not too many complain about.

No, engines didn't need to operate perfectly. N-1 has less gross liftoff mass (GLOM) than Saturn-5, yet N-1 had higher liftoff trust. That's partially because it was supposed to complete the mission with up to 4 engines out during flight.
Came here to write about this. Phage therapy[0] is an extremely interesting topic and there are a number of startups working in this direction. It's funny, but in Eastern Europe (Georgia, Russia, Poland, etc.) phage therapy is used broadly for many years, whereas US is just catching up.

[0] https://en.wikipedia.org/wiki/Phage_therapy
Yikes, when did HN become so full of haters? This is easily one of the most exciting startups out there at the moment. It would be a game changer for so many people living in Europe and Asia who would love to live outside the US and commute to the US regularly for work.

Is it the everyman's plane? Certainly not. But it essentially makes living in Tokyo/Hong Kong/Singapore/Sydney and working in SF much closer to living in New York and working in SF (which a lot of senior executives and investors do). Imagine if Australia East Coast was a 6hr flight and 5hr time difference to SF. New York is a 6hr flight and a 3hr time difference to SF. Seems a lot different all of a sudden doesn't it?

Focussing on gas is the complete wrong way of looking at this. Humans and our ideas are the ultimate resource, not gas. When we work together we solve problems, and the weapon engineer who had to relocate back to HK to raise kids near family can often be the difference between a breakthrough we all benefit from and nothing at all. Having these senior people able to work locally can enable them to seed their hometowns with thriving local offices that train new generations of talent.

Tesla won in cars and SpaceX won in rockets (both very complex industries) over very well established incumbents. Don't underestimate how much organizational dynamics can weigh on a company. Do you think the best people at Boeing are going to risk the next decade of their career working on a plane that might only do 300 orders when they could go get easy promotion working on the next 787?

Good luck to the team at Boom!!
Just for Fun: My Ancient Artifact in Operation
Well, I can speak to this since I work for a company that does this. The improvement in microscope image analysis by computers in the past 5 years has been amazing. If the trajectory continues, I would say that 25% of image analysis will be automated using DNNs and other machine learning techniques.

Areas where it won't work: any time you have new image data that doesn't resemble what the networks were trained on. In fact, most people in the field recommend training on and running inference on a single microscope and if you change scopes, you have to retrain your model! Obviously data augmentation has a lot to contribute there but there a ton of challenges.

I've actually proposed building a warehouse-scale microscopy facility within a couple miles of amazon or google data center with full realtime reinforcement learning loop. If you have hundreds of near-identical scopes collecting the same data, you can train over the variation.
To add a bit more color to the above thought:

He also collapsed after one of the games from dehydration, had to be taken to the hospital, and was not effective in any games afterwards. Maybe he had a little too much energy?
Some good resources to brush up on before it is released.

https://www.eff.org/issues/coders/reverse-engineering-faq

https://en.wikibooks.org/wiki/Reverse_Engineering/Legal_Aspe...
Apparently nobody understands that the super rich make their income from long term capital gains treatment on stocks and this won't touch the wealth of the top 1% meaningfully anyway.

TL;DR - Buffet, Gates, and Bezos will still be stupid rich and this won't solve anything.
while 8X it's great deal it has extremely mediocre baskets compared to iPhone, heck even Xiaomi Mi A2 for like 160€ has better camera

and no you can't root Huawei phones without unlocking bootloader, not unless you are willing to part with significant fee to shady third party for something which was provided for free by Huawei
Most likely not. Since everyone uses IDA I don't think there is anything better. ( also NSA probably also use IDA )
I don't see the problem.

First, SQLite's developers are not an open source company funded by VCs. I don't know what funding they had originally, but they've leveraged their success into a well-funded consortium. Does it matter if it could or could not work in combination with VC funding? No: what matters is that the developers got funding, end of story.

Second, I don't see why a company (regardless of funding source) couldn't spin off a consortium to fund further development of some open source created by that company.

Your goal seems to be "profit", which is a fine business goal. Open source is a fine business tool, but not so much a fine business _goal_. It can help you profit, but it can also hinder. Open source is a business tool to be applied on a case-by-case basis.

Open source is not easy to use as a core business value. That's because the most important core value to any public corporation is profit, and open source does not intrinsically lead to profit. Building a for-profit business around open source projects with open source as a core business value is undoubtedly difficult. Indeed, the example I gave is of a non-for-profit organization that funds development of one project.

Open source is a tool with following costs and benefits (and risks), some of which are:

- cost: loss of confidentiality for "secret sauce"
embodied in open source
- cost: the cost of opening a code base and keeping it open
- cost: dealing with a community

- benefit: good will
- benefit: mind share (this is the big one)
- benefit: quality (hopefully) contributions from
the community
- benefit: credit (especially for developers, which
functions as a form of compensation and
recruitment incentives)

If for some project open source is a tool whose costs exceed the benefits, then don't open source that project. It's that simple.
" it's VCs who want their money back times ten"

Keep in mind that this is the market speaking, not a 'specific need of some group'.

If it costs money to productize and support something, and it's risky, it's going to be VC and there will be terms that take that risk into account.

Another way of saying it is that '10x' requirement is a function of the risk of the business model of those taking the money. (Which by the way, as you point out, might involved 'over estimating the worth of something)

Most VC's are not successful and even the 'obscene' amounts of money made by some actually don't make up for losses elsewhere. [1]

Also, it's a very risky proposition for most folks to do a 'true' open source project and as you say make it 'profitable' via sponsorships or whatever.

" it's VCs who want their money back times ten"

Keep in mind that this is the market speaking, not a 'specific need of some group'.

If it costs money to productize and support something, and it's risky, it's going to be VC and there will be terms that take that risk into account.

Another way of saying it is that '10x' requirement is a function of the business model of those taking the money. (Which by the way, as you point out, might involved 'over estimating the worth of something)

Most VC's are not successful and even the 'obscene' amounts of money made by some actually don't make up for losses elsewhere. [1]

Also, it's a very risky proposition for most folks to do a 'true' open source project and as you say make it 'profitable' via sponsorships or whatever.

[1] https://techcrunch.com/2017/06/01/the-meeting-that-showed-me...
The claim isn't never--it's for installing a small set of apps that you don't change for more or less the entire lifetime of your device.
Top Five Tips for Public Speaking
So, this is a Delaware C Corp? Have you filed your annual report and paid your tax-year 2018 taxes? If not, you need to do that. You will also, at this point, have to file an annual return and pay 2019 taxes. Once that is done, you can file a certificate of dissolution.

That's basically it.

If you qualified to do business in a particular state, you likely need to file something with that state surrendering your qualification to do business. That's a simple filing as well.

Any competent corporate attorney can handle this quickly and for not much cost.
It's often required by the government where the hotel is located.
Precisely. During one nasty ice storm at night I might see more wrecked cars in a single hour than I see the rest of the year combined. And no currently available automation system would dare operate in those conditions, so human drivers take a huge statistical hit from conditions like that but the computers don't. All of these 'safer than humans' metrics are apples to oranges.
In general all lighter roasts have more caffeine than the same beans roasted to a darker state. Espresso uses a particularly dark roast and is relatively lower in caffeine content. Of course you don’t drink normal coffee in single shots, and you know the old saying, “Quantity has a quality of its own.” Sipping a beer will get you as much alcohol as shot of whisky, but you can work several shots into a single cocktail.
Yes! Config maps are coming very soon, just doing a bit of testing to ensure they're safely isolated. This is the next feature we'll add for sure!

As for services, that gets tricky due to our shared cluster design, and for now services can only be created thru the interface. Were working on tools that show users what their service yaml ought to be, but we're mostly focusing on demoing and educating users about the Deployment object. Via the interface you can expose an HTTP service (and we'll handle HTTPS termination), and TCP <-> internet is coming soon!

Thanks for giving it a test run!!
> Windows gets this right and is able to iterate faster on kernel interfaces as a result.

The only place that'd have any bearing is for modified syscalls. Newly added obviously aren't an issue, And looking at syscalls removed, it's because they removed whole subsystems that never had anyone using it. Those would probably not even get upstreamed into the mainline kernel to being with.

I'm not seeing any evidence of what you're saying while looking at how the NT syscall layer has changed over the past couple decades.

https://j00ru.vexillium.org/syscalls/nt/64/
Bootstrap v5 forms
Do the companies that you're starting or investing in with the $10m/yr you earn need that cash? Do you think Uncle Sam can do a better job of investing it than, say, Warren Buffett or Elon Musk?

It's not like rich people just sit around on piles of money like Scrooge McDuck. They put that money to work so that they can earn some interest. The government will happily just spend it, though. So should it be doled out by congresspeople to their friends, or should it be invested by someone shrewd enough to be making $10m/yr in the first place?
If you are actually interested in learning more about networking, i cannot recommend starting your own homelab enough.

networking seems to be a hit or miss for people, some people find it very logical and "easy" while others seem convinced it's black magic.

networking basics is rather easy, the problem is complexity that gets added when you scale. (although i doubt you would reach that point in a homelab though).
Robbing someone of 70% of their income is way more aggravating and profoundly totalitarian than a simple progressive tax. It's one thing to grant a small share of your income to the state in order to keep social institutions running, but it's an entirely different thing if the state robs you off the majority of your total income for no reason at all.

In a free and democratic society, a citizen has the right to the fruit of his labour, not just to a small fraction of what he worked for.
They at least are trying and are inspired competition
> For an example, here is a slice of life one that isn't so extreme https://www.youtube.com/watch?v=fhkE3e7lT_g

That was beautiful, and nothing at all like the sexual ones we're discussing.
> The available evidence suggests that the main legitimate concern regarding caffeine and energy drink use is the potential negative impact on sleep but that, otherwise, there is no cause for concern regarding caffeine use in the general population.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4264529/
Are you saying that they did not cite any of the papers on this list [0]? Or that they didn't cite the pop-sci books and articles? I don't know, just curious. (I think the former would be bad, but the latter would be more OK.)

[0] https://www.sens.org/research/publications
What do you mean by "solving today's problems" ?
Merely being able to do math in floating point doesn't make a chip appropriate for NN training.
We figured it's better to start small and increase the limits as we can, rather than have to back-peddle and decrease them, but for most "demo" applications this limit gets you pretty far. Also, we don't document it (we should and will!) but the CPU can burst, so you're not strictly limited to 0.02 cores, that's just what you would be limited to assuming 100% utilization on our end, which shouldn't occur do to our cluster auto-scaling.
They are if you paying millions a year. Athletes, big corporates, etc.
Even worse if money spent on armaments, wars, soldiers and these are used to destroy things it's even more toxic economically - you're not just burning wealth, you're using it to destroy other wealth as well - foreign development aid carefully given benefits everyone far more
The fact that articles like this sloppily conflate income from labor and income from capital, while also citing Piketty's mammoth tome (which is almost entirely focused on the profound differences between the two) is incredibly disappointing.

Taxing somebody who earns $500,000 USD per year laboring is not the same as taxing somebody who earns $500,000 USD per year through ownership of capital.

The latter is undoubtedly very rich; the former might be, or might be on their way (assuming they save and sustain the income).

The latter is providing economic value (maybe, maybe not) through mere ownership (rent-collection); the former is economic providing value (probably) through selling their labor.

These things do not have the same systemic effects.

As Piketty makes clear, taxing labor was the preferred form of tax collection in the mid-20th century (when taxation increased most rapidly as a portion of global GDP) because most income was collected from labor after the capital destruction of the two world wars. Now, the proportion of income from capital to income from labor has almost doubled to ~8:1.

We do not live in the same world, and taxing wealth makes far, far more sense both morally and economically than taxing labor. They should not be sloppily conflated.
The other aspect is you just have corporations buying assets for the use of their owners which sidesteps income tax as a whole.
USSR landed Lunokhod-1 and Lunokhod-2, and also returned lunar soil samples in programs Luna-16, Luna-20 and Luna-24. Those are all separate flights.
Well, as a patent troll and supplier to the Nazis, their positives would have to be pretty big to outweigh their negatives.
Autumn can now resize iTerm2 by pixel
And not a one of them is anywhere near level 4 self driving.
You will often get downvoted for humor on HN. On the other hand, I have at times gotten double digits worth of karma for a humorous post. I guess you have to appeal to a certain type of person.
> Apparently nobody understands that the super rich make their income from long term capital gains treatment on stocks and this won't touch the wealth of the top 1% meaningfully anyway.

Then why not create a higher-rate long term capital gains tax-bracket for those people, when you're also increasing the income tax rate for them?
I feel like all we need is "one Ring to rule them all" - one app to run on all the mobile and desktop OSes and in web browsers and I can see no reason why do we need different kinds of apps for these (there hardly even is such a thing as a web site today actually - all the websites, this included, are apps, just styled and implemented differently and optimized for bigger screens). Perhaps Flutter (or something else to come) is going to let us achieve this.
I had the same problem and then quit with the first round of chemo treatment for Hodgkin's Disease, and certainly not because I had an epiphany.

It must have been one, or a combination of the many drugs against nausea, vertigo etc. I strongly suspect that the mild euphoria caused by the Corticosteroids played an important role.