skysight-inc/HackerNews huggingface dataset:
Biologics do not contain living organisms. They contain proteins manufactured by genetically modified organisms.
Meditation seems to be able to shrink the amygdala: https://www.washingtonpost.com/news/inspired-life/wp/2015/05...
I find this comment confusing, as there's no expectation of entrepreneurs to create jobs- its just a side effect of trying to make money. I agree with the top comment where this feels like more of the same and when the subsidy/vc money dries up they are going to be fired just as if they were a contractor as the company dissolves. There just wasn't anything in this piece that felt like more than a template fluff about how company X creates a service around consumer product Y and is paying some token people a few dollars over minimum wage. Which in itself is fine, but there was no real information on how they were going to sustain themselves and become a stable business.

The thing that irks me about this article is the feeling that it's going to be used as a powerpoint footnote/feel good slide forever well after the primary person in this article has long since departed.
That is sad, I wish they do 480hz and we could see if it strain as much.
I'm not saying they are (these type of patents suck), I'm just commenting on the fact that Qualcomm really want's a court ruling on LTE modems. They want to force Apple back to the negotiating table, and IMO this ruling isn't enough.
And it's still miles better than Hulu, who seem to have this compulsion to make their UI worse and less usable every 6 months or so.
Protein chains are used by all living cells to manufacture the molecules we're made of. They arrange soure material into new molecules. Many proteins are intended to manufacture themselves. This capability is usually tightly regulated by availability of the source materials within cells.

Prions are proteins too. And they can create themselves from source material too. But their source material are proteins which are not intended for processing. As such, prions are defined like weeds in a garden: They're not supposed to be there.

Marvel at the wonderful world that is biology: https://en.wikipedia.org/wiki/Protein
Why Amazon Go's reported move into airports would make a lot of sense
Yes, you would have been prohibited from being in a Madoff fund by LAW, the literal no peasants allowed law (Reg D)

So whats your point?
The Isaacson bio was a joke. Made countless basic factual errors. Wouldn't trust it on anything.
I went this route. Nightmare. The installer software has been removed for Mac and isn't available anywhere. Had to find a laptop running Windows 7 to get it up and running. It also won't be compatible with modern routers. 1/10 can not recommend.
One important distinction between a clock an the mechanism is that clocks can be would up and run "by themselves". Perhaps this was the missing key? (Though, this would not preclude them from creating "mills" run by wind/water to display time.

Another thing to consider is that the concept of doing things at a specific time may not have matter to much of the worlds population at the time and, even though they were capable; there was no demand.
Well on the TV side, Friends, for example. Netflix is coughing up $100M to keep it for another year because people are flipping their lids about losing it. Also, you're taking the definition of "classic" far too literally. There's any number of movies from the 80s, 90s, 00s, etc. that Netflix just doesn't have or shuffle in and out of the service within a matter of months that are of far greater appeal than something Netflix cooked up in the span of six months. That's the difference between "lots of content" and "lots of content that people want to see."

> I think more people want to watch "Thor: Ragnarok"

Again, say bye-bye to that one in the near future when Disney's streaming service starts, and in its place we'll get some Netflix junk that no one's ever heard of. See the problem here?
Total Annihilation
What Will It Take to Make Finance More Gender-Balanced?
I had always understood it as a check of confidence. If the smallest, trivial item was taken care of; you can be fairly certain that everything else was completed as you'd expect.
I don't pay for either, but I'd also add:

Netflix has a threshold level of quality. There's probably plenty on there I wouldn't want to watch, but nothing that I'd deem offensively bad.

YouTube, however, I find to be increasingly toxic. There is some amazing content on YouTube, which is often superior to traditional media, but I find I need to wade through increasing levels of garbage to get to it.
Madoff's funds weren't exactly exchange-traded, generic investment vehicles. As mentioned in the article, part of the money is clawed back from "feeder funds". Those were sales or regulatory vehicles that passed 100% of their capital on to Madoff.

As to your examples:

Person X is irrelevant. You claw back the money from fund Y. Fund Y may, in turn, have arrangements with person X requiring them to return any money, but that's actually tangential. (this is like 1st-semester law again, yeay!)

Person A owes <total sum taken out> - <total sum put in> (this is like 10th grade math again. yeay!)
> unfortunately they don't notify you

That sucks. In Sweden it's the law that credit reporting agencies have to send you a copy containing the same information every time someone does a pull on your credit. Seems like a common-sense regulation.
I'd recommend adding Ishitani Furniture to your woodworking list. Very relaxing and the he makes gorgeous stuff.
iPhones are made in Chinese special export zones (SEZ) that lack taxes on imported raw components and factory machinery. The flip side is that anything made in an SEZ must be “imported” back into China since the inputs themselves were technically not imported.
Why should I be glad? I'm paying for it. If they're not spending on effective efforts against legitimate threats, that money is, at best, wasted and I'm still exposed to those threats. At worst, maybe my own money will one day be used against me in prosecuting a victimless crime. The likely middle ground is my own money is being wasted to violate my own privacy for no good reason. This isn't sounding very good to me.
Just because you have never met someone who garnered that kind of reaction from you doesn't mean such people don't exist.
People increasingly trying to turn the web into an application layer instead of writing actual applications.
Similar situation here. I'm wondering if this might be enough to stop me from trying my own Mastodon instance. Might be nice to not have to support even more platforms.
It appears this is Airplay 1 only (please correct me if I'm wrong) so this will not be as nice as say, using an Airport Express but if you had this stuff laying around it might be worth it.
Airplay 2 haas reduced latency and improved quality. You can also stream to multiple Airplay 2 devices from iOS while iTunes on a Mac/PC can stream to multiple Airplay 1 devices.
Software Engineering Academic Genealogy
I think imposter syndrome is something completely different - a result of answers begetting more unanswerable questions and the "hard" not feeling significant anymore. Thus it becomes "Anyone who can do N dimensional vector calculus can do what I do but I can't even come up with a way to unify physics or prove or disprove P = NP, I'm a failure and a fraud." Even though there are say only 5 people in the world capable of rederiving his work in a year.

The runaway progression is the same however. That happens in some cases with eating disorders - even when ribs are showing and they weigh under 100lbs they are convinced they are fat.
Can you explain? Whose control over what?
I live with chronic pain. (ankylosing spondylitis)

I take prescription NSAIDs and other drugs for a long time. Also a lot of acetaminophen per day. (Which I carefully monitor.) I also take, occasionally, narcotic pain killers (hydrocodone). Next January (2019) will be ten years since I added hydrocodone to the drugs I use for this.

But it is a tool. Nothing more. I take it only when I need it. I don't have any predictable usage pattern. It is for occasional use only. I have a very healthy fear of taking it at all, but if I'm in enough pain, I'll overcome that and take some. I have a good life and don't want to screw it up with narcotic pain killers. I have never had any resistance when asking for a refill. Neither my primary doctor nor arthritis specialist are worried that I'm taking too much.

If anything, I've noticed that in the last couple years, I've slowed down my usage a little bit. (Measured by time between refills.)

I think in pain management, the first thing is "learn to live with it", and then, "there are good drugs for days when it is really bad". (just IMO) I'm always looking for the lowest dose I can take that will be effective for any particular episode. I don't want to build up a tolerance. And I suppose I must not have built up a tolerance in ten years of occasional use.

I haven't become addicted. But I also don't drink alcohol. Or smoke. Or use very much caffeine. Maybe that is related, or maybe not.

I would say that hydrocodone has improved my quality of life. I get out and do things I sometimes wouldn't otherwise do.

Last year I was in Colorado and tried some, .... uh, ... products. First, I thought they were pretty pricey compared to hydrocodone, which costs me only $5 for a bottle of 30. Second, while they did help some, I didn't think they were nearly as effective. The hydrocodone is more like a nuclear weapon for pain.
I'm curious, doesn't the GDPR require sites allow users to download all their data, in other words their questions and answers on Quora? The article claims they don't allow this.
The Raspberry Pi has awful noisy audio out. There are some nice Amps you can get like the HiFi Berry. I set up a nice arrangement in my old lab with with these.
~20 years ago my parents bought us(me) a new computer. A Pentium 2. For almost the exact same price(not adjusted) as the fairly well specced gaming computer i bought last year.

Prices drop for a lot of stuff. Thinking youtube for $15/month is expensive doesn't seem wierd to me. But i think its worth it just to avoid ads.

> mad max furry road...

What a movie that would have been :)
There are plenty of ways that a protein could be mis-folded. There is a lot of bumpiness in a cell (though this is unlikely to lead to this). A random mutation (through some sort of radiation) could change a piece of DNA or RNA, causing the protein to be made incorrectly. All of these are frighteningly unlikely. But happen so often they are almost certain to do so in a large enough time, with a large enough population.

The similarities to the 'corrupted blood incident' start and end with them both spreading to others in a local area. Prions don't really suggest that life is a simulation.
No, they do not work relative to a point. You replace the first 4 digits of the code (the area code) with a location name that's clearly in the area, the following digits stay the same. The name resolution of the location can be off by kilometers and it still works.
Wow - talk about a helicopter perspective! Fascinating read and really brings home the point that, while "Product Management" is a relatively new term, the role and skill set have been around since there were products to sell!
There doesn't seem to be the right niche. Maybe if they restricted it to fiction and documentaries but Vimeo already has that niche covered. Maybe Netflix could acquire Vimeo. btw imo Vimeo has a lot of excellent videos. They're more open to trying new things so sometimes they have something really good or deep that you would never find on YouTube or Netflix.
Except that they buy it at that price
I use mobile dictation frequently since I prefer typing on a full-sized keyboard over typing on a mobile phone screen. I find it works pretty well for me (using iOS 12 on an iPhone 6s). If I am in an area with poor connectivity or in a noisy environment, or if I am using unfamiliar words, it may not work as well, but for my purposes, I find I spend far less time dictating and occasionally correcting what I meant to say over manually typing in text. I utilize the "blue underline" feature to help train the system to recognize words I say when the dictation software gets confused.
Warm Dense Matter can be thought of as ionized jello.
Gold's value comes from two main things - it's nice for jewellery and it's expensive to mine. The price has for many centuries approximated (within 3x or so) the mining cost and it doesn't drop to zero because it made nice jewellery from Varnian jewellery 6000 years ago (http://www.ancientfacts.net/7-oldest-pieces-jewelry-world/) to modern wedding rings and that's not changing in a hurry. Both mining costs and market price are about $1200/oz at the moment. Financial uses are a secondary effect that has kind of come and gone.
Are you using Joplin for notes sync?

I like Nextcloud, but I have to admit that I quickly get lost when I explore addons/integrations.
How has it managed to escape me, immersed in tech every day for many years, that there is such a thing as a USB soundcard? Crazy how things can slip through the cracks, be so close yet missed.
I did the same thing a couple of weeks ago using a Raspberry Pi 3 B+. I have it connected to a Cambridge Audio stereo amplifier through USB, since the amplifier has an integrated DAC. I'm very pleased with it, and it was surprisingly easy to get working.
I didn't downvote, but it did take me only a couple of Wikipedia clicks to bring up the article on Neapolitan Novels (https://en.wikipedia.org/wiki/Neapolitan_Novels). Per the article "the series has sold 10 million copies in 40 countries".

It also apparently had enough clout to get an HBO / RAI TV series produced out of it, which will possibly up the recognition factor for her name and her works considerably depending on the success.

This is not super super stardom level (the top living novelists have sold half a billion novels -- https://en.wikipedia.org/wiki/List_of_best-selling_fiction_a...) but that's still an impressive number, I would say it is within the top tier.

(A fun comparison to another HBO show: When Game of Thrones started, A Song of Ice and Fire had sold 15 million copies worldwide -- https://en.wikipedia.org/w/index.php?title=A_Song_of_Ice_and... . In a similar ballpark, in other words.)
According to the article its 16.5 light hours from the sun.

That sounds both tiny and absolutely massive.

For reference it takes 8 mins for light to reach earth, and just over 5 hours for light to reach Pluto.
Couldn't we use something like KL divergence to measure the difference between a given bulb's spectral distribution and a perfect black body?
> The real challenge is and always has been how to combine or embed symbolic reasoning capabilities efficiently within a fuzzier approximator, allowing for “getting close” in a fuzzy way then fine tuning it using more advanced rules.

Well, maybe the problem is that we spent so much time basing models on the visual part of the brain that we overlooked the rest:

https://www.quantamagazine.org/new-ai-strategy-mimics-how-br...
GitHub Services Brownout Updates and Timeline
What every game developer needs to know about getting parental permissions right
Eh? Are you talking about this https://support.apple.com/kb/DL1664?viewlocale=en_US&locale=... - also available for iOS?

It's still there. I have an Airport Extreme that very happily updated itself to support Airplay 2 a few months again
You have a much greater need on a bike to see road detail, you need to look out for potholes and sticks on the road. In a car, you just need to be able to see the road lines and reflect light off of signs.

I use a 1200 lumen bike light, powered by two 3500mah 18650s.
Qualcomm CEO and CFO keep talking that they are at the door step of fixing what ever differences they have with Apple, and should be done by early 2019. And yet nothing on the table suggest Apple and Qualcomm could settle without long Court Battle.

I kept thinking Qualcomm might have a Nuclear option that will force Apple to listen or at least talk into resolution. May be some software patents?
At the risk of being a bit off topic … A lot of people interested in Airplay will be looking at this post wondering how to use AirPlay with UPnP or ChromeCast devices. shairport-sync [1] (used in the article) only works directly with audio hardware, so won't work with Chromecast or UPnP compatible systems. I've tried many many different open-source bridges and finally found AirConnect [2] which is by far the most reliable, active and well-maintained bridge. philippe44 responds to every issue filed (as far as I can tell). Works great with my Sonos PLAY:1 & XBox.

[1] https://github.com/mikebrady/shairport-sync
[2] https://github.com/philippe44/AirConnect
IMO Netflix has done well in this regard by transforming themselves into a content company rather than a content delivery service. Recently most of my favorite shows on Netflix have been 1st party titles, and I can't think of another content producer who's output is as varied and as high-quality as Netflix at the moment. Maybe Disney has the IP and the raw muscle to pull this off, but they will have to prove it.

I actually think competition is good for the space. As I said, I think Netflix is really good now, but if they became an uncontested monopoly in the streaming space, I would fear that quality would suffer.
> For starters, you're assuming I'd want to live off the investment, instead of continuing to work.

Okay, fine. You mentioned that you're a student, so I'll assume that means you're 22: if you're a man, that means you have another 55 years. That $100,000 thus works out to an extra $1,818/year for the rest of your life, which is roughly a month's rent or a dozen or two really good meals a year. Is that a nice supplement to your wealth? Sure. Is it enough to make your life significantly better? No, not really.

Ah, but perhaps you're investing it, too. Let's say that you get 6% a year (optimistic), and withdraw 1/55th of the principal + interest each year. So this year you'll get $1,927, next year you'll get $2,006 &c. Is it nice to have that extra money? Sure! Is it going to be life-altering? No, not really.
For those who don't agree, I think the difference may be competition experience. It's like other high pressure scenarios, but preparing for a match can teach you how to prepare for others. My level of nervousness is pretty well correlated to how prepared I feel. The best competitors go into a match "knowing" they will win because they had covered all the bases.
That whole book (not just the linked chapter about command-line options) - i.e. TAOUP - The Art Of Unix Programming - by ESR (Eric Steven Raymond, of Cathedral and Bazaar fame) - is good (although verbose and using many heavy words and verbal flourishes in his trademark style). I've read most of it. The Rules section stands out.

Being a Unix user and dev (above, not at the kernel level) for a long time before reading it, it crystallized and verbalized for me many concepts and unspoken techniques that are sort of hazily known and used but taken for granted (although applied instinctively) - although I had also figured out and sort of verbalized some of those on my own before reading the book.

Also, related, anyone interested in learning to write (not just use) their own command-line utilities in C on Linux, may like to check out this tutorial I wrote for IBM developerWorks:

https://jugad2.blogspot.com/2014/09/my-ibm-developerworks-ar...

It was on the site for long, got 30-40K views, and good ratings (4/5). Clients and others I know have used the tutorial as a guide to creating production command-line utilities. Follow the selpg links recursively to get to the PDF of the article and the source code.

I first wrote the utility that is used as a case study in the article, for production use at one of the largest motorcycle manufacturers in the world.
Why are prion diseases typically brain diseases?

Or is that the only organ where they manifest in symptoms?
Seems like documentation has already been able to handle this for centuries, via table of contents, overviews, introductions, detail sections etc, and readers have handled that fine.

Instead of adding work to the authors, simply use the semantic markup...or even let the reader do so.
We should have a Hacker News MMA meetup :)
Maybe the things I sent to Apple, so they could start cutting into YouTube should also be sent to Netflix? :D
You've got to admit that they were accurate about Intel's 10nm problems pretty consistently. And they were right about NVidia's excess inventory problem delaying consumer Volta. They aren't always accurate, but 2018 has been a pretty good year for them.
A very bright bike light makes it much more comfortable to ride a bike at night, you need to compete with car headlights so that you can see the surface of the road in front of you. Cars don't need to worry about the road conditions as much as cyclists since if they hit a pothole or a stick, it's no big deal.
wonder if there's any recourse?
Nassim Taleb, the Lindy Effect and how to choose your next book
I bought a Google Chromecast Audio. Spotify, Soundcloud and Pocket Casts support it on iOS. I'm not actually sure what the officially Apple sanctioned way of getting audio to my speakers is, but I haven't felt the need to find out either.
if you and your employer are concerned about this, why are you mail ordering laptops instead of buying them in cash at the store?
Is there a book that teaches you more about this stuff? I'm getting more and more interested in this after reading the cancer drugs people in China are making. This seems like a fun experiment to do at home for a weekend.
I worked for a company where we gave you two modes to view things (a A/V version with bullet points, and a text transcript version). Its cool in concept. BUT, once you get into this you're doubling the amount of work as an author for very little gain (unless the modes are "instruction-ally purposeful" in some way). In addition, if you do any multi-lingual work (we did), you've doubled your translation cost per language as well.

Its also hard to validate the perspectives of your users. One TLDR user isn't the same as another - one wants 2-3 paragraphs another wants three bullets. You can put in that work here, but... its work. And you're not guaranteeing anyone ever sees the bulk of your long-form to which you probably want them to see to make a lasting connection and because you put the effort in to generate.
Laravel Spark may be an option
This use of half-rectified lighting is especially true of LED Christmas lights. I haven't yet dug in on how to change them to at least full-rectified, which look much better to my eyes.

Is it just a matter of adding a bridge rectifier? I guess I'd need to add some resistors in there also to dim the emitters since they'll be on twice as often (to prevent premature burn-out).

Has anybody looked into this? I'll admit to being a bit eccentric.
If you were an early employee at Facebook it takes significant self-awareness to realize that that success may not be directly linked to your formidable brain power. Especially if you that was your formative professional experience in your 20s.
JIRA isn't an antipattern, but it does enable people/teams to use antipatterns. This is silly.
anxeyeity
Why a 25th window? If you're that into cats, you'd surely be receiving many, many cat pictures on Christmas anyway.
Building a GraphQL API with Django
Yes. Also the active ingredient in Wart remover, though at higher concentrations (2% for stridex and 17% for wart remover). Good at melting skin I guess.
The problem I have is that the reference points do not respect natural or human boundaries. Around where I live, the reference points Google Maps give are variously an adjacent town (the other side of a major river!) and a small housing estate which no-one living outside that estate will be aware of.

If Google want people to use this system, they need to give a choice of reference points.