skysight-inc/HackerNews huggingface dataset:
Photosynthesis as an argument is more 'it is possible that quantum effects have a place here' - that said it is a long leap given that our retinas are technically quantum just by processing particle-wave dualities. The quantum /computing/ is what is relevant to proof of there being any 'special sauce' to the human brain vs just a bunch of parallel processing power.

Essentially the quantum effects are necessary for a quantum consciousness but are definitely not sufficient. Personally I can see one way to make that link which is quite a long-shot.

Given what little I know from quantum computing and cryptography comparing parallel processing solving speed relative to problem sizes vs quantum approaches would give a theoretical basis for distinguishing the /computing/ aspects.

If human brains are able to solve progressive problems with a time increase more consistent with qubit processing than non-quantum computing combined with heuristics it would hint at quantum processing power. Needless to say that is a major tall order and would probably result in most humans failing to complete period.
Does CCR5 have no other purpose? Hard to believe that it'd exist if it wasn't needed.
I've personally never considered them secure because of stuff like the gummi bear hack [0] popping up semi-regularly [1]. That they say "in recent years" researchers have demonstrated ways to fool them tells me these occurrences are less well-known than I thought.

[0] https://www.theregister.co.uk/2002/05/16/gummi_bears_defeat_...

[1] https://whatis.techtarget.com/definition/gummy-bear-hack
The fact that Fascism doesn't mean Fascism any more and is now synonymous with whatever flavour of authoritarianism the speaker wants it to mean.
Hacking PNR https://media.ccc.de/v/33c3-7964-where_in_the_world_is_carme... at time of the talk (2 years ago) used/discussed these sites:

https://matrix.itasoftware.com/ to get detailed fare rules & restrictions

https://www.expertflyer.com & https://itunes.apple.com/us/app/seat-alerts/id533533342

https://www.checkmytrip.com/ allows entering name & booking-reference and gives all detail

https://www.viewtrip.com/

https://tripcase.com will use name + booking-reference to get detailed PNR information including the first name

https://www.fly.kiev.ua can make a flight reservation without a payment, still gives an 6char booking-reference
Homozygous CCR5 mutations cause "immunity" against HIV and heterozygous causes a slower disease course. I do not think this applies to all strains of HIV. Unsure.
Sure, but then he's building for $100/sqft in SF, which is laughable. Going rates right now are closer to $400/sqft at the low-end, without permitting. I get aiming for smaller units to improve affordability, but the assumptions aren't grounded in reality.
I don't know if there is a good place to draw the line... but free sure is in the "hey no reason to trust this in any way" zone for me.
>A complete lie.

How do you know it's a lie?
Somewhat off-topic and shameless plug, I'm working on a meta flight-search engine that finds the cheapest flights from multiple origins to the same destination (i.e. me and some friends who live in another city want to fly to Hong Kong with no particular date in mind, just want the cheapest flights and with overlapping departure/return dates). Does anyone else have a similar need or know of anything that can do this?
"good but error prone" describes all of medical care right now. Hell, pharmaceuticals aren't even good in many cases.
I wonder what old techies think/thought about being forced to wear suits/ties.
Is this corruption or incompetence? I honestly think it’s corruption. Why can’t we just outsource this to a European engineering company that is capable of accomplishing this? It just makes no sense to me.
Why?

Seriously why? We do so many unnatural things to us through technology. The article discusses editing genes to try and prevent viruses.
Here is a simple argument - if you can prevent disease, you should.
Dang is a cuck who can't do anything about his gf's short clothes arousing flame wars in guys dicks. So he comes and takes it out here. Dang be a man and maybe stop the other side too? (gf and antinationals).
Here- https://news.ycombinator.com/item?id=18531288
Genetic engineering might be able to prevent certain inherited diseases, but otherwise major net improvements are unlikely. A boost in one area tends to cause problems in other areas. That's why evolution through natural selection hasn't significantly increased average human intelligence over the past few thousand years. The average human genome appears to be close to a local maximum.
> Considering about 400k combinations [1] on a 3x3 board with a 30sec lockdown every 5 tries it will take on average about 14 days to unlock (given that the pattern is random enough).

Not very imaginative. One of my brother's friends got into my brother's phone on the very first try by holding it up to a light and looking at the smudge pattern on the screen. A tapped-out 4-digit PIN would at least stop this method from working so easily.
He's from South Africa, IIRC.
It was a gift to the creditors.
> I think doing one of the javascript ones might have produced better job prospects.

> Currently working on a MacOS desktop app that might make a few bucks, but probably not.

Why not make your side project a javascript oriented one? Two birds with one stone.
My thought exactly. When I've clicked on the link, I was intrigued, but then I've read the headline and all the magic disappeared.
My phones been in the shop for the last week thanks to an unfortunate incident with the washing machine and it's given me some new perspectives. Many of what I'd call "vital" features of a smartphone now seem to be net negatives, others are only important because I don't have the old way anymore.

PT App: I didn't realize how frequently I checked my light rail app, telling me how long until the next one arrives. Now that I don't have it I realize it only added stress for something largely out of my control, knowing if the next one is 3 minutes or 5 minutes away doesn't affect when I'll get to work. It would still be useful in some situations but I hope to use it a lot less in future.

Clock: My phone was my watch and like the PT app this mostly cause stress about arriving to work on time which mostly involved factors beyond my control. I just try to leave this house on time and I'll get there when I get there.

Reddit: Haven't missed it. Again it's probably adding stress for no real gain.

Internet: Haven't missed it.

Alarm Clock: Miraculously I haven't slept in during the last week and most day's I'm up earlier because can't roll over and go back to sleep without the alarm clock telling me to get up. I could also buy a dedicated alarm clock, it's very rare I get any value from a portable one.

Phone: This one wouldn't generally worry me but this week I've had a sick family member and really needed it. If I had a home phone that would have been more than enough, maybe I should get an IP phone again.

Weather: Turns out the seven day forecast is just noise I don't really need. The morning news tells me if I'll need to wear another layer or not and that's enough.

Music and E-books: This is the one feature I've really missed.

Overall it's amazing how much time and money I've spent on these little devices that offer very little value.
Reminded me of this 2014 article:

New NPR Boss: ‘We’re Going to Be Talking About Brands That Matter a Little Bit More

https://fair.org/home/new-npr-boss-were-going-to-be-talking-...
I've worked with enough legacy code to know that playing around with seemingly unused areas can have unexpected consequences.

The trouble here is that we can't see those consequences until they end up hurting someone.
It would be fun if an fpga implementation was done, perhaps from the vlsi design described in [1] "Design of LISP-based Processors, or SCHEME: A Dielectric LISP, or Finite Memories Considered Harmful, or LAMBDA: The Ultimate Opcode". I can imagine an asic could fit an array of those and use little power, given advances in densities since 1979.

[1] https://dspace.mit.edu/handle/1721.1/5731
do you think this site is ok, does it need something else?
"Changes in traits, such as IQ, by 5+ standard deviations"... Where in the world are you getting this from? This is unlikely to be true for a long time. Intelligence, as far as genetics controls it, is a complex trait... with few if any large effect (especially positive) mutations.
> It's ethically black

What does that mean?
That's absolutely not the standard for deciding to conduct an experiment on humans.
Here is a controversial article published in 2013 by an evolutionary psychologist that everyone should give some thoughts on:

Disclaimers: I do not have the expertise to evaluate its veracity but if true it will affect everyone in the world in some important ways within a few decades (the effects might already start to appear as we see how fast China has developed technologically. Yes, technology transfer is clearly a factor but few developing nations can absorb and adopt advanced technologies so rapidly). I also have not pondered deeply enough to have a strong position on the complicated ethical implications alluded to in the article and expressed with concerns elsewhere.

https://www.edge.org/response-detail/23838

> ...

> Deng also encouraged assortative mating through promoting urbanization and higher education, so bright, hard-working young people could meet each other more easily, increasing the proportion of children who would be at the upper extremes of intelligence and conscientiousness. ...

> But crucially, Comprehensive National Power also includes "biopower": creating the world's highest-quality human capital in terms of the Chinese population's genes, health, and education ...

> The BGI Cognitive Genomics Project is currently doing whole-genome sequencing of 1,000 very-high-IQ people around the world, hunting for sets of sets of IQ-predicting alleles. I know because I recently contributed my DNA to the project, not fully understanding the implications. These IQ gene-sets will be found eventually—but will probably be used mostly in China, for China. Potentially, the results would allow all Chinese couples to maximize the intelligence of their offspring by selecting among their own fertilized eggs for the one or two that include the highest likelihood of the highest intelligence. Given the Mendelian genetic lottery, the kids produced by any one couple typically differ by 5 to 15 IQ points. So this method of "preimplantation embryo selection" might allow IQ within every Chinese family to increase by 5 to 15 IQ points per generation. After a couple of generations, it would be game over for Western global competitiveness. ...

> My real worry is the Western response. The most likely response, given Euro-American ideological biases, would be a bioethical panic that leads to criticism of Chinese population policy with the same self-righteous hypocrisy that we have shown in criticizing various Chinese socio-cultural policies. But the global stakes are too high for us to act that stupidly and short-sightedly. A more mature response would be based on mutual civilizational respect, asking—what can we learn from what the Chinese are doing, how can we help them, and how can they help us to keep up as they create their brave new world?
Not really. There are lots of vestigial things in humans that are no longer needed.

Tailbones, for instance.
Then fine by Net Worth and not by Income. Fine by Tax paid. And made it like the Tax system the more you have the higher percentage.

There are people who just park their car anywhere and paid parking tickets, they really don't care because it was too small amount of money.

If anything, people should realise the level of inequality has become. How unfair and unjust the system has made against the bottom half of the population.
The title of the post doesn't work because it doesn't "scratch an itch" as in it doesn't suggest how it makes life easier for common problems.

Titles are hard. "Light wrapper for manipulating structured data" is ok but it still sucks because you aren't showing the destination. I'll think about it
Chinese scientists are creating CRISPR babies using gene editing
I learned Rust after learning Python. I do solve similar problems in Rust as I did in Python.

The single worst thing that python thought me, is that it would be cool/useful to make classes. Some call that a “sea of objects”. When I tried similar concepts in Rust I learn quickly that things started falling apart much faster at a point reached much earlier.

However this was also happening in Python – only much later in the game. This made me realize: instead of focusing on the flow of data and useful abstractions (”blackboxes”) over it, I actually made a lot of classes and objects and tried to pipe them into each other, without giving too much thought on the flow of data.

It felt so reassuring to make a Car-class for car objects, wit a Wheel class for its wheels, that I somehow forgot to think about the actual data that I wanted to work on.

The danger of OOP is IMO that it highly encourages bringing in preexisting patterns of abstraction that seem to make so much sense that you discard other, potentially more useful abstractions.

I have more broken Python code than I have broken Rust code, and one of the reasons is, that a lot of the stuff I did in Python (rightfully so) wouldn’t even compile in Rust.
I have been distinctly unimpressed with open peer review, and given it's antithetical to something I actually think does concretely have benefit (double-blind peer review) I've gotten rather curmudgeonly about it as a fix.
In the short term I think the risks are overstated. Vastly increased health and intelligence looks like it will be possible to select and/or edit for, as well as the elimination of Mendelian disease. The scale of this good is so large it overwhelms most scruples.
https://en.wikipedia.org/wiki/CCR5#Potential_costs
The modern biomedical ethical framework comes out of Nuremburg in response to Nazi atrocities.

https://en.wikipedia.org/wiki/Nuremberg_Code
You can make bank transfers out (HK / international) with a business account. For personal accounts you can spend with the card at the moment, but bank transfers are coming soon.
While this is a great development, hosting AUTHORITATIVE text of the law at a private service (GitHub, owned by Microsoft) doesn't sound like a good idea.

Consider what would happen if Microsoft decided to delete the repo. There will still be copies of the law at different places, but there would no authoritative version. Imagine a lawsuit where each party is arguing that their copy of the law is the "correct" one.
>Criminals have more rights than children.

This is the most succinct way I’ve seen it explained and it’s 100% accurate. You’re also right about the fear of upholding the law. It’s sad AND ridiculous.

A relevant article about another local offender cops just ignore: https://www.sfchronicle.com/bayarea/heatherknight/article/Co...
Edit: misread
Having gotten a failure to pay ticket on metro the first time I ride for not understanding the system I can tell you it's quite steep $90 in 2000. And it only takes the officers about four stops to walk the whole train. That's a lot of rides without a fare ticket to pay for the one penalty ticket.

Also you can often get tickets from other riders. I get asked for my stubs every time I'm in town
"Can prevent disease" implies that you are not doing experimentation. If you're doing experiments, it means you don't know if you can.
Obesity is generally caused by eating too many calories. The real cause of being fat is too many calories and not enough movement. The fault is at the fork, not the farm.
People have tried this, or spins on it, and they don't particularly gain traction. Part of the problem is these have to exist alongside the traditional structure, and "Hey academics, do you want to be busier for intangible rewards?" is a hard sell.
Nope. I'd be in favor of shorter copyright terms in general. The truth about $40 prices are that they aren't intended really to be the fair price of a good. They're there simply to allow the subscription business model to work. So no, I don't like the fact that we charge $40 for a 31 year-old paper. And I'm a huge proponent of shifting to a non-subscription business model. And the publishers are shifting, albeit slowly and only because they're being forced to. But they are shifting, at least in STM fields, and I'd guess that this $40 byproduct of the subscription model will indeed die out when the subscription model shifts to the open access author pays model (which, of course, we can also debate for a long time).
Strange, the title says jaywalking, but the body says running a red light.
https://news.ycombinator.com/item?id=18530906
Compared to any transit system in another developed country, BART is absolutely lawless.
Let's say you get past recruiters and/or HR. You're sitting in a room full of potential coworkers who question how you wake up in the morning and put on your pants because they went to a four year school and have that degree. It's a club and you're not in it.
You are forgoing the tax revenue that would've been earned by the workers as well as any benefits that they claim.

In Australia it was estimated that each auto job produces 6 other jobs through network effects [1]. All up that number would be fairly substantial and likely enough to justify some subsidies/bailouts.

[1] - https://www.aph.gov.au/Parliamentary_Business/Committees/Sen...
The USPS allegation was 100% untrue as reported by the postmaster general (who you think would be someone Trump would have consulted).

The tax stuff is really none of his damn business (because it is really a state tax code issue at this point, not a federal issue)

If Trump does anything to attack Apple, it will be because he things doing so will benefit the US economy (likely because someone else told him it would). Things like convincing Apple to make certain parts in the US, even if doing so would increase prices in the US (and dramatically do so elsewhere in the world).
Knowing how social engineering hacks work so you don't fall as victims
You're right, except then they support destructive politicians that says the reason they don't have a job in coal anymore is because of "scapegoat of the day" (global warming lies? the EU? Immigrants? not killing puppies?)
For reference, good peer review is incentivized in some places. A journal I read gives awards every year for the best reviewers, and good reviewers end up as Associate Editors.
But it is an opinion. Being an assertion doesn't prevent it from being an opinion.

You and I could very well find arguments for defending it, even while fitting the current morale.
https://news.ycombinator.com/item?id=18530906

70+ points
And the suppliers, whom other automakers also rely on.
> "gene is for CCR5, which currently doesn’t have known function"

It's in the article:

> "Even if editing worked perfectly, people without normal CCR5 genes face higher risks of getting certain other viruses, such as West Nile, and of dying from the flu. Since there are many ways to prevent HIV infection and it's very treatable if it occurs, those other medical risks are a concern, Musunuru said."
No, they mean that ethically it's black in the same way that we describe blackhat vs whitehat hackers.
I've been paid (in credit for more books) for two reviews of book proposals.
This is not true. Intelligence is polygenic. The average human is no Von Neumann. At the very least genetic engineering could raise average IQ to Von Neumann’s level. We know that phenotype is possible with no ill effects. It will likely take us much further.
How to Spot Influencer Fraud
Stackoverflow data is free for anyone to download and reuse. Gmaps is a proprietary dataset. Helping people on SO also feels a lot less like working for a tech megacorp for free.
Living the American Dream, in Canada
I claim that it’s better to request major revisions than recommend rejection, but that’s mostly due to my lack of faith in authors.

Too many examples of “oh well, let’s try the next journal” and not enough of “gee maybe we should fix these glaring flaws”. It’s not because I’m a nice person; it’s because I would prefer the literature not to be a toxic waste dump. Nobody is entitled to be published anywhere. In an ideal world, doubly blinded review would become a part of the published record. At some journals it already does.

The reviews offer valuable context, which is often sorely lacking in high profile venues. (The canonical examples of STAP and arseniclife come to mind, but also much more subtle details where an overall sound paper somehow only gets cited for the one shaky assertion in the results)

JMHO
> not morally or ethically defensible

Sure, that won't stop progress by people who do not follow your flavor of morality or ethics, though.
I guess calling it all-out fascist is perhaps a hyperbole. But it's creeping authoritarianism.

To me though, having police posted with dogs at train stations just looks especially authoritarian. Police dogs (whether drug dogs or attack dogs) are primarily a tool for intimidation.
Moral frontiers aside, current gene tech is still not where we'd like it to be in order to pull of these sorts of things and know we haven't done harm. Side edits are a big problem with CRISPR-Cas9.
The CONS microprocessor (1974) [pdf]
> To respond succinctly to your comments: money isn't the only incentive in life, so it seems weird to not see "any incentive" as soon as money is taken out of the picture.

Especially for a group of people where many of them have taken a pass on more monetarily lucrative careers.
That's basically what will happen now, except the tax payer is also in the hole.
I’ll take a suit and tie that I can remove as soon as I get behind the closed door of my private office over a kegerator, shorts, and an open office hellscape. A piece of cloth around your neck wasn’t the only thing the old days had to offer.
This is why I always advocate for platform languages on production code.

Too many hours spent in the past writing FFI code, tracking down bugs not knowing if they were on the platform or 3rd party language runtime, missing integration with platform tooling.

Naturally I don't always succeed at that.
A couple hundred megabytes to show me a map of where I am right now is huge.
"unethical" would probably have worked better. sorry for the confusion
This. "Service to the university and field" is literally part of my contract.
He has Canadian citizenship (along with South Africa and US) and went to college at Queen's University in Canada.
See other comments but literally inside the US calls are not what I am talking about. WhatsApp is used internationally.
I had randomly received a bunch of postcards for incorrect google maps address confirmations recently at my office. Made me stop for a sec and think about how that system works, and the why/
who would try to send out fake requests.
You haven't addressed my point. No one disputes that intelligence is partly genetic. However if it was possible to raise intelligence through genetic engineering with no ill effects then why hasn't evolution increased the incidence of that phenotype already?
Human intelligence has not increased because it has not been strongly selected for. If it was maximized, at the expense of other traits, a lot could definitely happen.

> The average human genome appears to be close to a local maximum.

Absolutely, but it's maximized for the environment we lived in 10-100 generations ago.
AAI Cancels Air Odisha’s UDAN License
6 reasons why you should blog as a software developer
It has a very strange type system. Funny syntax. Lots of unexpected behavior. Also could be compiled relatively easily if it behaved better, there are a lot of funky edge cases. It's also bad as a general computing language - anything where you aren't just computing on a bunch of matrices.

Nowadays I'd say just use python -- it's not _quite_ as nice when it comes to computing on matrices, but it's _much_ nicer when it comes to everything else.