skysight-inc/HackerNews huggingface dataset:
> Sure, there's a real question of how to pay for treatments for rare diseases. But the millions in development are a sunk cost. To take his ball and bat and stomp off would be disappointing in any circumstances. But when people will die because of it?

If people actually cared about treating patients, they would be crowdfunding that treatment rather than trying to fleece the people who invested man-decades of work into developing them, and who bear the mandatory cost of following these patients forever.

How about we just stop developing drugs, and live and die by the same ailments for the rest of time, as the patents expire. That would stop people from shifting the goalposts so dramatically every time somebody gets off their ass to actually produce a treatment.

The potential cost of care will continue to rise as long as we develop treatments for previously untreated or undertreated ailments; and it seems like the potential for care haunts people by giving the impression that they're being deprived of something, when the alternative is really that the treatment would not exist if insurers (government or private) would not be willing to pay something close to that much for it.

These people are dead without treatment, whether it's because of pricing (and insufficient social support [it could be literally impossible to fund all therapies of this sort for all patients]), or because the researchers were discouraged from ever developing it. The pricing is not arbitrary, so your only two options are a) don't develop it, and therefore never realize the moral hazard, or b) develop it, and market it to justify the work, so that you can do the same in the future, and treat at least some people, hopefully being able to reduce the cost of treatment in the future.
Maps can serve as a chart of data relations and/or a listing for easy lookup. But, yeah, it's disappointing most people dislike non-map charts with geographic categories.
I was pretty surprised that gmail was successful. I didn't imagine that people wouldn't care that their email wasn't on their own computer. But, there you go.
depends on when they bought their shares...
Not without a license.
That implies that they aren't lapdogs just not beholden to the administration.
Ah come on, the truth is not at all that altavista didn't spy, or didn't do ads. It's that they (and exite, yahoo, infoseek, ...) completely overdid the spying and ads and Google instead massively optimized their backend.

And then a crisis came boom no more competitors.

Google was the least obtrusive of all of the search competitors, and the most useful. That was their great strength.

Man thinking about when this happened, it's now some 20 years ago. I'm old.
Sole and Despotic Dominion: Fiction
Why Are Engineers Getting DevOps Fatigue?
Our species' collective intelligence isn't that simple.

It appears to me that we are processing substrate for a species-sized game of Core Wars. In turn, because the size of the playing field (aka total human population) has become so large, the outcomes of the game now can produce existential threats, something amplified by the speed at which everything runs.

When there were only 200 million humans, communicating by voice and using only muscle power, the ultimate impact of slow AIs running on Homo Sapiens hardware was bounded. Now, closing in on 8 billion of us with considerable upgrades in the form of industrial- and information-age technology, the output of the game can not just break the board, but flip the table.
What is the idea with these garish MS Paint graphics? Am I the only one finding them incredibly distracting?
Vue 3.0 is reported to support class-baed components natively: https://medium.com/the-vue-point/plans-for-the-next-iteratio...
So Amazon offering more and more business services, or in other words doing more tasks that other businesses used to do.

And the interesting thing is, that they found almost a risk free way(for them), to do those tasks. Which fits Bezos's experience as an investor, always dealing with profit vs risk.

For example, for small/medium companies, creating efficient supply chains for varying demand was risky. But for Amazon, with it's size and great demand control and forecasting, it's probably not that risky.

The same with creating a new private brand - Amazon has a lot of knowledge of what sells, They control free ad inventory, and they control their customer, via search.

So it would be interesting to ask: what things businesses do are still risky - and would be left to external companies to do ? And what risky things can Amazon de-risk and take in-house ?
This was actually a fairly interesting article, except for the strange tone - amazon isn't hiding that these are their brands, they seem to be flagged as "our brand" all over the place. so what's with the mspaint red circles pointing out incredibly obvious associations? Is this supposed to be satire, or does the author really believe they've discovered some sort of conspiracy here?
One interesting benefit of using such a large provider is that if a breach or bad behavior were to happen large portions of the internet would suffer, and you'll receive a much smaller portion of the blame. The S3 outage last year was terrible for my employer, but hardly anyone noticed because much more significant sites were similarly suffering.
Are you disagreeing with me? I'm not sure where, since I've said:

"What seems real to me is the inside-outside distinction..."

"...the analysis of [-2..2] is questionable." [So the rest of the negative number line swapping inside and outside is not questionable.]
Indeed. If negative results can be published too and made useful for others, reduction in forged successes could be a side benefit.
Nvidia is more trouble only that you need to install the proprietary driver rather than using what comes with the kernel. You also need vdpau if you want hardware decoding of video.
I'm curious if you've actually used an IMAP client witha Gmail account; if so, which one(s).

A sibling comment has already mentioned the folder/flags mixup issue, but while it sounds like one small feature, that one thing is so fundamentally broken that I really can't see how any user of Gmail IMAP would overlook it.

I get duplicate notifications for the same mail in INBOX and [Gmail]/All Mail and actions on one copy don't affect the other unless clients implement Gmail-specific hacks (which many/most do).

What RFCs are you referring to?
As long as JavaScript is the only language that runs in the browser, I expect it to stay at the top. Not necessarily because its the best or the favorite language, but because it is the only language. It is like having a chart of how many women versus men give birth. Shockingly women are still at the top.
That's my fault personally. I recently put a significant amount of money into it. It happens every time I buy something.
I'm sure that's true, but I assume that many of these clients either wouldn't have been written this way or would have adapted by now if Gmail did things differently.
The reason that it would have an “in-built audience” is due to the superset relationship, that’s why I think it is.
I always thought it'd be a really cool start-up idea to have a service that prints, binds, etc.. and mails you within a few days a printed paper like this.

I probably have 10 papers floating around, loose pages. Annoying. I print them when I want to read them but of course rarely can immediately.
Ask HN: Why do we want to learn something new when we don't have time?
While you are in busy, you want to learn or create something new. But, not when you have free time. It's always happened to me. And I ask some of my few friends and they said the same thing as well.

Can HN explain me why and how to overcome that?
Inadequate Equilibria - Where and How civilizations get stuck

By Eliezer Yudkowsky

First book in a long time which really made me see the world differently and taught better thinking.

[0] https://equilibriabook.com
The most telling paragraph in the article is the last one:

> "As is often the case with Amazon, what seem like strange or inexplicable new behaviors are often old retail strategies unfolding on the internet, quickly, and in plainer view. Brooke Mille is no more a lie than any other brand: It’s just newer and faster and more online. And it has a lot more company."

In other words, nothing new here, Amazon is doing what retailers have always done, just on Internet scale. As someone who worked in retail for a long time, I kept waiting for the punchline but I should have read that last paragraph first.

It's hard for me to figure out why this is newsworthy. I wish the New York Times would stop publishing stuff like this. Amazon does a lot that is interesting, evil, novel, etc. to report on. This article just adds noise.
Some people maybe, but I doubt it's "most" people.

The point of using Vue is data-binding with reactive models and components.

For your use case I agree Vue is overkill. A templating engine should be enough.
Thanks, I will do that.
Gravitation, by Charles W. Misner, Kip S. Thorne, and John Archibald
>> Bezos recently talked about how Amazon would eventually fail

Peter Thiel said: " So anyone who has a monopoly will pretend that they are in incredible competition". This seems like one of those cases.
On the extreme end of "brand value you've got Kanye West selling a 100% cotton t-shirt for $120. (1)

On the other end you've got Amazon not even bothering with a logo and selling a 100% cotton t-shirt for $14.99. (2)

And the Amazon shirt is rated 4.5+ stars.

As a consumer I love what Amazon is doing,

Retail "brands" are the most notorious of all of the middle men.

And they had to be - how do you deliver a product to a physical retail location that needs at least a 2 - 3x on each product sold to pay the rent, the front of house employees, etc?

As a result these "brands" were never product innovators, mostly they're perfunctory with giant marketing budgets to build their "brand value".

Remember Nike's "pumps" innovation back in the day? Was that a product innovation or was that a marketing innovation?

And this reality in retail brands has led to all sorts of notorious abuses - on the subject of Nike they famously figured out how to arbitrage child labor - relying on shit hold labor conditions for ~30 years until they got caught truly well and good with their pants down w/a famous LIFE Magazine story.(3)

Amazon's supply chain innovations flattened the market, and now we see cases as laid out here where the overseas factory owner is building the brands, or building the brands in collaboration with Amazon. It's not going to be perfect, but at least it's a step in the right direction.

Amazon is clearly in the middle of calibrating their own own morale compass, but as a consumer I delight in seeing the mid-market retail kings getting stomped on.

(1) https://www.okayplayer.com/news/style-kanye-west-apc-120-pla...

(2) https://www.amazon.com/Goodthreads-Short-Sleeve-Crewneck-Cot...

(3) http://mallenbaker.net/article/clear-reflection/nike-and-chi...
It's bad to analyze this issue through the medium of a long-form article, which wraps the story up in emotional narrative. Here is a better write-up in the MIT Technology review: https://www.technologyreview.com/s/601165/the-worlds-most-ex....

The gist of the problem is this:

> The Amsterdam company spent more than $100 million testing the drug and carving a path through Europe’s medical rules and regulations, which weren’t geared to consider a new technology like gene therapy. Initially, for instance, regulators said they expected a clinical trial of 342 patients. Executives wryly noted that there were only 250 people with the disease in all of Europe.

> Nor has Glybera convinced the national regulators in Europe who decide what drugs get reimbursed. Last year, French authorities said they would not pay for the drug. Germany judged Glybera’s benefits “non-quantifiable.” It leaves doctors and insurers to make decisions on a case-by-case basis.

Here's a drug that cost $100 million to make, and will require even more money to move through clinical trials in the U.S. And the pool of potential patients is a less than 1,000 people, and oh many of then can't pay either because they lack insurance (U.S.) or the cost/benefit panel math doesn't work out (Europe).

Viewing this after-the-fact leads one astray, into thinking there is some problem with the system that leaves this potential cure out of the hands of patients. Patents, money, it's all just a proxy for effort in, benefit out. Even if you had the government make this drug, you're talking huge amounts of money per patient, which few governments would pony up. (And rightfully so, because you could save a lot more lives with that amount of tax dollars.) The answer is probably that this drug doesn't make economic sense, and the abandonment of it by the maker is just an indication that it was a misguided effort to begin with.
Ugh, fine with me. The whole "affordable housing" racket needs some real solutions. The current ones cost way too much money and provide far too few apartments. The solution to high and rising rents for everyone is not to start a lottery system for a few thousand subsidized apartments. That doesn't address the problem at all.

What's worse - a lot of these programs mandate things to private developers, thus raising prices for the market-rate middle class units. Double whammy.
Last I checked this should be possible with some contortions on your end; Linguist (the tool GitHub uses to detect repo language) has some hardcoded paths which it will ignore for the purpose of counting lines of code. See this issue where Servo managed to convince GitHub to count it as a Rust project rather than an HTML project: https://github.com/servo/servo/issues/6332
Not sure about that. The high school stars in my example were the effortlessly smart sort (high IQ, crammed before exams).

But to your other point about working hard only when it's needed, there is a class of skills (so called "bicycle skills" [1]) that have to be learned in advance, and cannot be picked up on the fly. Mastering those skills early in life can lead to compound interest payoffs later on. So I don't agree with YAGNI as a general rule.

Furthermore, even if the material you learn isn't going to be useful, it doesn't mean that the process of learning them is necessarily wasted. On the contrary, the process of acquiring mastery itself can pay dividends in the form of meta-skills. Take learning to play the piano for instance. The blogger "Ask a Korean" has this to say: [2]

"The point of learning the piano is NOT about acquiring the skill of playing the piano so that the student can earn a living as a pianist. It is about building the character of the person. Here is the thing about character -- you can't build it by explicitly setting out to build it. Character is not a skill like tying your shoelaces. If it must be put in terms of "skill", character is a "meta-skill" -- a foundational human skill that is necessary to perfect any number of mechanical skills. And the only way to develop this meta-skill is to develop at least one highly sophisticated mechanical skill, such that the student may acquire the meta-skill in the course of building the mechanical skill."

[1] https://www.johndcook.com/blog/2012/08/01/bicycle-skills/

[2] http://askakorean.blogspot.com/2011/05/confucianism-and-kore...
Do you have regular 1:1s with your now former mgr or current director? If so I would have been bringing this up on the regular, not to complain but to talk about how much you’re enjoying the new role and looking for feedback on how it’s going from their perspective.

The only way to know if you’re in their plans is to talk about it, and the sooner you bring it up the better.

Lesson time: feedback on major review cycles should never be a huge surprise. That goes for downward feedback, but it also goes for upward feedback too. Your director is already making plans for next year. Make sure they know what you want and what your view of the current status quo is.

One thing I’m not sure on is, do you want to manage? People management is a whole different beast than the tasks you’re currently taking on.
Show HN: Founders launching startups on Twitch
new vehicle. but used? lots of second cars are beaters. does demand in the used market induce manufacture of more cars? hard to see how.
That's fine as long as your customers have the same expectations of the level of security you're providing as you do, and you're complying with appropriate legislation around handling of customer personal and business data :)
Bahamas, Progress being made on crypto assets legislation
There is a very good book which talks about “The long now”. About expanding now from just the present to longer periods of decades, centuries and millenia.

Really helps in setting things into perspective - https://www.amazon.com/Clock-Long-Now-Time-Responsibility/dp...
Heya!

I’m Armin, part of the team behind the 24 Hour Startup Challenge!

Over this weekend, there are over 300 founders building products live on Twitch in 24 hours. As I post this, there are almost 90 people live streaming their work from all over the world! You can watch them on 24hrstartup.com.

The idea behind this live-streamed hackathon event comes from Pat Walls. He challenged himself to do a 24-hour startup twice this year and live-streamed his process. He is currently moderating and interviewing people from the maker community in our main stream.

Initially, we planned for about 50 participants but were overwhelmed with sign-ups. People are motivated to do this, and you can see that in their streams! We think it’s great to watch everyone make their crazy ideas reality, so we wanted to share :)

A few products being built right now:

* Heartbeat Canvas - Generate art from your heartbeat

* Privacy First Products - A curated list where you can discuss privacy first products

* EpilepsyBlocker - Disable GIFs that may cause epilepsy

Let us know what you think!

Armin (& Melanie & Pat)
I agree with the article, but it doesn't belong on HN.
Based on article the price is not at 1M because of high manufacturing costs, but because they want to have return on the investment made during the research and development phase.
Its popular to paint amzn as a boogyman
I fear that, given the culture that seems to be permeating law schools, no legal advocacy group will step up to fill the principled role that ACLU has abandoned, and the republic will fall again for the same boring reasons it always does.
Possibly http://www.structuredprocrastination.com
X.509 (TLS/SSL) Certificates Survival Guide (2013)
That is true but if you can get Domain Admin access, generally getting application access is pretty simple after that, and as getting DA is pretty simple if the domain hasn't been locked down (like the one in the post had), it's a reasonable place to go...
> waymo

So how is your waymo car going?

Does it drive well?

Does it get good mpg?

Is it that secure?

Waymo is one of the worst offenders:

https://www.cnet.com/news/googles-sergey-brin-youll-ride-in-...

It was promised in 2012 to be completed in 2017... 2018 is ending and there is still no waymo anywhere besides on google's hands.

While Google has been promising that didn't deliver, not even close, others have been actually delivering self-driving cars to the hands of real costumers and don't get any credit.
It just backs out to interest rates commensurate with the risk. Lack of collateral doesn't mean you can't get a loan.

Perhaps the economics wouldn't work, but it sure sounds like nobody tried in this case. What it would boil down to is if the insurance company expected a larger net cost on a traditional drug regimen for the life of the patient, vs servicing a loan at the market rate over N years. Interest rates are still very low so in general debt is seeking out risk.
'Dungeons and Dragons' Releases Errata for Core Rulebooks
ClickHouse for Time Series
One good thing to come of this is that I learned about https://www.thefire.org which seems to be picking up the baton where the ACLU dropped it (in terms of education advocacy.)

Here is their take on Title IX https://www.thefire.org/new-proposed-title-ix-regulations-fe...
The thing is that things like Active Directory are very useful in managing large numbers of systems and users. Ditching them would make IT much more expensive to run and, as many companies view operational IT as an expense to be minimized, that's a hard argument to carry.
I think it’s highly likely that Cloudflare is at least associated with the NSA/CIA, maybe more. Also Google, Facebook. One of the reasons I don’t own a Home/Alexa/etc. I value privacy.
This is off-topic, but yes. https://spark.apache.org/docs/latest/mllib-data-types.html shows some strategies for representing distributed 2d arrays, and it is straightforward to generalize these to more dimensions or to unfold the multidimensional array into a 2d array.
I have this, but the recent UI refresh broke it.

https://github.com/bijij/ViewImage/issues/166
99.9% of drivers are in the kernel nto downloaded from random spots on the internet. The big exception is proprietary gpu drivers which user friendly distros provide packages for in the repos.

The big issue is thus. If you intend to run linux don't buy random hardware and hope it supports linux then complain linux is hard to make work. This is a natural course because people have all sorts of existing hardware and no real desire to buy new. It's also reasonable to try because linux does support a lot of hardware. Try it and if you like how the environment but not how works with your machine buy your next machine with linux in mind.
In China now the goal is the make surveillance omnipresent. Already in premier universities, including Peking University, classroom lectures are routinely surveilled to monitor inappropriate discourse.
Trying?

This is not trying.

This is effing up every other possible competitor.

If someone goes to a dumb VC asking for money for a product that is actually feasible, they will be turned down because they read on Forbes that google is making that miraculous device that is stupidly ridiculous in so many levels.... but hey! It's google! A Fortune 500 company and its on Forbes!
That's a fascinating definition of poverty. It's certainly not an internationally recognised one. Have you ever been to England? People in Birmingham or Manchester are certainly not living in poverty by any reasonable definition of the term.
Nice story and a good illustration that a lot of good IT Security isn't buying fancy "next gen" products, it's doing the basics of managing your systems well.

It costs more to run IT well, but there are good payoffs, like this.
>Time is so mysterious and it may not even be a constant rate.

The word "rate" as you're using it loses all meaning when you're measuring how much time passes over a period of time.
All of that was public knowledge since the beginning of Facebook:

"Check this site out: www.harvardconnection.com and then go to harvardconnection.com/datehome.php. Someone is already trying to make a dating site. But they made a mistake haha. They asked me to make it for them. So I'm like delaying it so it won't be ready until after the facebook thing comes out."

https://www.businessinsider.com/how-facebook-was-founded-201...

"ZUCK: yea so if you ever need info about anyone at harvard

ZUCK: just ask

ZUCK: i have over 4000 emails, pictures, addresses, sns

FRIEND: what!? how’d you manage that one?

ZUCK: people just submitted it

ZUCK: i don’t know why

ZUCK: they “trust me”

ZUCK: dumb fucks"

https://www.businessinsider.com/embarrassing-and-damaging-zu...

And don't even let me get started on how Zuckerberg behaved towards fellow executives and co-founders.
Radial Solenoid Engine – homebuilt aircraft-style electric rotary engine [video]
Thanks, MTE