skysight-inc/HackerNews huggingface dataset:
So I was expecting another story about some IP troll buying the rights to a drug with a monopoly and then jacking up the price (like the whole EpiPen fiasco) but this wasn't that.

There's an old Chris Rock bit about Big Pharma where he says there'll never be another cure for HIV like there was for polio because there's no money in that. The money is in getting you to the next stop.

It's poignant because this isn't a theoretical scenario. Gilead recently was downgraded on declining revenues because they're wiping out the disease (Hepatitis C IIRC?).

So, back to Glybera. There are plenty of low-incidence diseases that are treated by expensive drugs to manage them. This is a lifelong commitment. Covering such drugs in company health plans can significantly increase the per-member costs.

If you have a drug that essentially cures the drug in one dose shouldn't that be weighed against the lifelong cost of covering a regime to manage the disease that is inferior? Multiply that by the disease being quite rare and sure, you end up with a $1 million price tag.

As further evidence for how screwed up the US health insurance system is: companies enroll in plans for their members typically for a period of a year or maybe a few years. Let's say your drug's price of $1m compares favourably to $100k/year for 40 years to manage the disease. How can a company who might only be covering the employees for 1-3 years be expected to cover that higher cost?

To be clear, this is further evidence of how stupid the US model is. In a single payer model this particular concern goes away.

How many rare genetic disorders are out there where $1 million per patient for an essentially complete cure isn't a bargain compared to the cost of managing the disease? Probably a lot. Is it fair to decry such expensive drugs just on their price tag without looking at the facts? Probably not but I bet you it will happen.
Harbor Freight does this, and they even try to associate with real brands. For example their house brand air tools are "Central Pneumatic," obviously similar to the much higher quality brand "Chicago Pneumatic." HF also call their house brand welders "Chicago Electric." A casual shopper might think they had simply misremembered which brand used the term "Chicago," and think they are buying a better quality air tool than they're really getting.
Imagine you have an application like GitHub Enterprise or Phabricator, something that has a web interface and SSH for git access. You might trust SSH, but do you trust the web stack to not have vulnerabilities?

I don't know about you, but I don't trust running third party apps, I won't publicly expose them. Instead I put them behind authenticating proxies, like Cloudflare Access[1], Google Identity-Aware Proxy[2], Bitly oauth2_proxy[3], and Buzzfeed SSO[4]. With an authenticating proxy an attacker can't even hit the web application until authenticating, so they can't exploit a vulnerability in the web application. They will have to pop the auth proxy first, which have less surface area, and then pop the web application.

Applications that combine HTTP and SSH complicate things because the typical HTTP proxy won't proxy your SSH (git) connections, and the web authentication flow doesn't work with SSH.

Cloudflare Access provides the auth proxy, cloudflared does the web authentication flow for a command line app and passes SSH traffic through Cloudflare Access.

[1] https://www.cloudflare.com/products/cloudflare-access/

[2] https://cloud.google.com/iap/

[3] https://github.com/bitly/oauth2_proxy

[4] https://github.com/buzzfeed/sso
You can tell the age/mentality of the person who wrote some of these names as they match very closely with my mental models. An "FTP Server" is inaccurate, but perfectly descriptive for me. Scripts is the same thing, "a small program which gets run repeatedly for a very specific task." So I think this is more of a guide for a 30-40 something dev who hasn't bothered to keep up with the proliferation of services.
>
You know Pocket is owned by Mozilla right?

That does not make it any better. So what if they did finally release the sources for the plugin (only took them a year or two to do). They have not released the server component. They are also using it to push ADs that I don't want. I should not have to toggle 50 different things and remove a bunch of stuff before I can use Firefox and then the next update undoes all of that.
I don't understand this -- we know there's pretty strong correlation between interstital fluid and blood sugar (which is how Dexcom and Lifestyle do their thing). If the correlation between blood sugar and tears isn't equivalent or better than that, what's the point?
Cool. However, stop calling it startups. They're launching apps/products, not startups.
Amazon is useless for high end outdoor gear. Not just gear even, but clothing. If something is available, it is often past years models, odd colors, sizes and the prices are non-competitive.
You are missing the whole point. As a designer that dabbles a bit in code and servers, I literally have NO idea what most of the words you just used mean.

I know that S3 has nothing to do with FTP, but it's a nice analogy that I can relate to. Get off your high horse.
Belle::vue, a WebAssembly browser templating engine for HTML5 C++ applications
The big problem with Cell is that it didn't come with a graphics stack. Sony apparently thought developers would be OK with building their own geometry/T&L/etc... engines and then were kind of surprised when that idea turned out to be unpopular. They were then forced to bolt a traditional GPU on the side to appease the developers.

Even if someone was crazy enough to build the entire graphics stack on the Cell, performance would likely not have been as good as a regular graphics card. It's hard to compete with hardware designed from the ground up for the task.
It seems a sprinkler system on the roof, in addition to the yard, would go a long way in terms of embers. Just keep everything saturated?
Nice to know that more people are aware of the "pipeline issue" as noted in the article.

So many people have experienced implicit bias as mathematicians, especially people who "shouldn't be good at math".
bfloat16 was first in DistBelief, so it actually predates TensorFlow and TPUs (I worked on both systems). IIRC the motivation was more about minimizing parameter exchange bandwidth for large-scale CPU clusters rather than minimizing memory bandwidth within accelerators, but the idea generalized.
> If WinAMP still had support

A company bought Winamp and is supporting/developing it again. A version supporting Windows 10 "leaked" just a few weeks ago.

https://techcrunch.com/2018/10/15/winamp-returns-in-2019-to-...
I'm sure it achieves that when you use Chrome on a recent developer workstation and only have one tab running. There is a nice JIT in the browser, plenty of RAM, and lots of high-end cores available for the task.

Today I'm struggling with 8 GiB of RAM and 2 cores. Admittedly I have many tabs open, but that is to be expected. Web site creators might believe that the world revolves around their web site, but really it does not, and so they must share my machine.

Weaker systems are of course unusable. Suppose the hardware is a 32-bit PowerPC Mac with one core and 512 MiB of RAM, and there are a bunch of tabs open to similarly taxing web sites or worse. I've mostly had to retire a system like this, which makes me really annoyed because it is quiet due to being fanless.

Note that the "weaker system" described above is not really weak. Long ago, I used the old gmail just fine with far less. There was a time when 32 MiB of RAM was enough to open several browser windows (we didn't have tabs) and run them. JIT didn't even exist yet, but the web ran fine.

It's the usual problem I think: software developers are rewarded with high-end developer workstations to keep them happy and productive, and then they test the software all by itself on this high-end hardware and everything looks good. Nobody is testing on older low-end hardware with lots of other things running in the background.
Alan Turing's "Computing Machinery and Intelligence" (1950). Describes the "Imitation Game", aka Turing test.

https://en.wikipedia.org/wiki/Computing_Machinery_and_Intell...
How is it great if I don't have the freedom to run my own server. Do you really trust that Mozilla won't hand over your browsing history and saved pages?
Spanish media now using AI startup to write select sports, finance articles
Forcing new and slow look forced me to move away from Gmail to private mail and Roundcube, works fine and fast.
yeah that's basically the TL;DR of it - the more "desktop app" type functionality you need in your web application, the more SPA technology you're liable to need.
<head shape="phalic"> lol
They really need verified vendors that Amazon can vouch for. These vendors would need to be tested without knowing by Amazon to make sure third party ones are not being sneaky. Especially if customers complain.
Title: Oil Demand for Cars Is Already Falling

2nd Paragraph Text: Oil use for cars peaks in the mid-2020s...

Ugh!
Plus, budget to hire a pen tester?!?
If you could turn off speculative execution completely I bet that would eliminate all the security concerns, but performance would be abysmal. The Linux kernel really can't be a "one size fits all" type of thing --- an environment where no mutually untrusting code is run has very different security requirements from shared cloud hosts, for example. Personally I think it's all a bit overblown, probably due to owners of the latter environments.
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Because of the TPM right? If you use bitlocker without a TPM you could boot to a live Linux USB and decrypt the bitlocker drive with dislocker.
Great story, but I wouldn't call it "failed" because it showed that the company has really good security procedures. I don't know many companies that could have resisted this sort of internal threat.

I've had pentests that found nothing before but I had logs full of attempts to compromise the app, including in some ways I'd never even heard of before. I didn't consider them to be failures either.
I can't confirm OPs number but I have in the past hired a car for less than 6 euro a day in Ireland.
Show HN: Most successful people have no idea what made them successful
How Plato Foresaw Facebook's Folly
Recipe feeds six. Making it for two.
CppCast: San Diego LEWG Trip Report with Ashley Hedberg
As far as I know California is already short on water. Would a sprinkler in every house system be sustainable or even possible in such conditions that everything burns?
But did that home burn from embers landing on the tiled roof, or from being consumed by the actual fire?
> What we should do is redefine the gram to be whatever 1e10 atoms of Hydrogen weighs, or something similar.

That was actually an alternative proposal for redefining the kg. The kg would have been 1000/28 the weight of a mole of silicon-28; you could build a sample by counting 6.023x10^26/28 atoms of silicon-28, and making a sphere out of them.

Initially the watt balance seemed to be less precise than atom counting, but then it was improved to a point where defining the kg on top of the mole became less convenient than the definition they are adopting now.
Look at the mass of comments in here shocked at the newfound lack of ethics in these institutions!
In the Christchurch earthquake in NZ, bricks were deadly. And Christchurch "didn't" have a faultline.

Also houses made from brick have a lot more damage in an earthquake - the mortar cracks and the structural integrity is lost.

That said, it was mostly older brick premises, chimneys, and facades that caused deaths. "Falling masonry killed 40 people in Christchurch's February 2011 earthquake"
What is a startup anyway?

The term is stupid and overused imo.
My problem isn't with the design, but with the fact that it's blocking every step of the way and being a buggy crap that not even the beta was.
But it's totally fine for corporations to meddle with the democratic process to push their own agendas, right?

Being and operating as a corporation is not some kind of natural right. It's a privilege, granted by citizens, via the the proxy of governments and their regulations.
I loved that too! Apparently there was Veblen craze in the US when that came out, Veblen societies everywhere. Here's a bit I liked:

...the cheap, and therefore indecorous, articles of daily consumption in modern industrial communities are commonly machine products; and the generic feature of the physiognomy of machine-made goods as compared with the hand-wrought article is their greater perfection in workmanship and greater accuracy in the detail execution of the design. Hence it comes about that the visible imperfections of the hand-wrought goods, being honorific, are accounted marks of superiority in point of beauty, or serviceability, or both. Hence has arisen that exaltation of the defective, of which John Ruskin and William Morris were such eager spokesmen in their time; and on this ground their propaganda of crudity and wasted effort has been taken up and carried forward since their time. And hence also the propaganda for a return to handicraft and household industry. So much of the work and speculations of this group of men as fairly comes under the characterisation here given would have been impossible at a time when the visibly more perfect goods were not the cheaper. - p162
Not in x86 architecture.
> People are amazed Amazon sells pasta and batteries under their own brand? Sounds like Ikea to me.

There's absolutely nothing interesting about Amazon doing this, it merely makes for a story because it's Amazon. Walmart has been doing it for 25 years as - by far - the world's largest retailer. They have four times the retail scale of Amazon. The Great Value brand is all over their stores, they also have numerous others such as Sam's Choice (since 1991).

Amazon's traditional online retail sales are close to growing at single digits now, they've seen a persistent slowdown quarter after quarter. Walmart's comps are the best they've been in a decade and their online sales growth has been accelerating again, climbing 40% in Q2 and 43% in Q3 (this is after rolling past the Jet.com numbers year over year as well; contrasted to eg 8% type online growth in 2016). If Amazon isn't careful, they're about to get their ass kicked in online retail. Unthinkable just a few years ago.

https://www.bloomberg.com/opinion/articles/2018-11-15/walmar...
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You would have to have a pressurized water storage tank at each house. It would be quite expensive and have a lot of maintenance for how rare the usage would actually be.
I still do run most programs on my own computer; I think is better. Often I write my own.

For email, I run my own server and I like Heirloom-mailx as the user program (I find it much better than Outlook), although you can also use others if you like to do.
The article claims a 30% perf slowdown with PHP. The majority of PHP workloads are single threaded. That causes me to suspect this impacts single core workloads too.
I have a hard time understanding that one.

When I want to compose, I look for a normal button in a normal place. I can't get used to a red button. My mind filters it out, like an ad. I pretty much don't see it. Every time, there is a sort of disoriented and bewildered search to find a compose button.

Was it supposed to have the opposite effect?
Cloudflare's Response to a Privacy Framework
> not in any literature

It would seem you are way over due as far as reading Frank Herbert’s Dune-series goes.
Telegram Crypto groups – all Group and all Countries
Hey All, just finished my 24hours working on https://moovoo.space/ you can find the whole experience here https://www.twitch.tv/czioutas/

The idea is to make a TV online but with content from indie film-makers, free movies (public content) etc without making the user pay!
USB boot most probably disabled in bios
Mike Dillard Most Profitable Success Tips – [VIDEO PROOF]
CA has frequent water shortages, and is in drought conditions right now. Where would the water for the sprinklers come from? What is going to raise it from the underground water source to the roof level? Electricity, which may not be available? Are you going to retrofit a large and heavy cistern on every roof, that relies on gravity to distribute the water?
In Norway hectograms are frequently used. We use them for things like potato salad at the deli counter, pick'n mix candy, berries and small-time-dealer quantities of hash.
"This is my everything list. It's everything I wanna get done."
When shopping at harbor freight just buy two... one for immediate use and the other for when the first breaks.
Strong agree. It’s hard to understand how you would build a sustainable business around any of the products listed in this thread.
I wouldn't describe an inch as arbitary, but it is customary. And variable before standardisation with different sizes of thumb! The basis of the metre in comparison is definitely arbitrary!
You can't run an (experimental) research program without a lot of money and even then most academic labs are run off a shoestring budget (reagents, lab space, instrumentation + maintenance/electricity for such, access to university and regional instrumentation e.g. synchrotrons, high field NMR, supercomputers, paying your full-time research staff i.e. mostly grad students and post-docs a working class wage)- even at elite institutions there's a heavy reliance on used and archaic equipment (hand-me-downs from the 80s and 90s). 'Grant grabbing' is strictly necessary for having the money to run a research program beyond something utterly barely bones (and likely fatally limited in scope in many fields as a result) on both instrumental/facilities access and output- and you can't get tenure and thus remain employed as an independent researcher without grants anywhere big anyway (grants are proof of promise/success and are necessary for engaging in ambitious projects- and the demand for academic tenure track positions is quite saturated so if you can't manage they can probably find someone else who can). Most faculty I know work (primarily writing grants and publication and to varying extents chewing through data and models with students) on weekends (and expect their personnel to do the same), especially ones still vying for tenure track (who often still work in the lab directly as well). The pay and hours are pretty poor relative to industry (abysmal if you consider time spent as a post-doc) and the stress is quite high- it's not something done in this day and age for the sake of wanting an easy road through life.

Essentially everyone planning to go into the basic sciences as their primary specialty needs to go and work in a laboratory anyway to some extent to get into grad school (my entire cohort did one to three years of lab work in undergraduate); and those who don't in my discipline are typically pre-meds (but who are still rewarded in apps for doing research so plenty of 'em did so) who have to do a lot of hospital volunteering and whatnot for their admissions process. However, undergraduates have less time to work, less experience/knowledge due to being partially through coursework, and are often less motivated because research isn't do-or-die for them like grad students and post-docs- taking them on can have opportunity costs for laboratories even though their labor is typically cheap or free.
> I could say that about Gmail/IMAP but their IMAP implementation is shitty and broken.

I believe the words you are looking for are “embrace” and “extend”.

And with undo and DRM in latest Gmail, we might as well add “extinguish”.
> On the other end you've got Amazon not even bothering with a logo and selling a 100% cotton t-shirt for $14.99. (2)

How is that better or different than any offerings from H&M? Or any of the other even lower end brands?
Ask HN: Safest anabolic steroid
Which is the safest anabolic steroid or any other drug which helps in muscle building but is safe.
I saw the social buttons and assumed end of article, very bad design.
Why is he that is on his high horse? It would take watching one or two videos on YouTube or Pluralsight to know on a high level what these services are.

If I came to you not knowing anything about the vocabulary used in your field of expertise is that your field’s fault or mine?
Last I heard it was declared economically viable and spun out. Wikipedia says Loon is currently contracted to provide internet service to a few particularly inaccessible chunks of Kenya, and its performance during the hurricanes last year is probably enough to guarantee its continued existence regardless.
For me what often works is to immediately note the idea down. My brain stops feeling the need to keep the idea warm in cache if it knows it's safely stored for later.
Students protest Zuckerberg-backed digital learning program
Ok, then physically remove the drive and plug it into a Linux computer.
Latest test ( 17 November 2018 ) :

"The Spectre/Meltdown Performance Impact On Linux 4.20, Decimating Benchmarks With New STIBP Overhead"

https://www.phoronix.com/scan.php?page=article&item=linux-42...
>I don’t think anything stood a chance. Look at, for instance, the Safeway in the town

Eh, I would disagree. Pull up google maps and drop in street view. This town, in the middle of fire country, is filled with pine trees. Many of them have ladder fuels under them. Tall fires happen because of crown fires.
Redux is an independent project from React. You could use redux with Vue. Your other points are valid but detracting from one library because people often use another you don’t care for seems outside the scope of React vs Vue.
To get even more pedantic, they are building apps, not launching them.

Not that I want to dismiss the efforts - a group of people all challenging themselves to build out a side project in 24 hours is commendable. But building an idea into an MVP on a Saturday is not the same thing as launching a company.
I just sacrifice sleep. A few months ago I thought it would be a great idea to audit Steven Skiena's algorithms course and see if I could implement it in JavaScript - 2 months later and a lot of sleep lost... https://www.userinterfacing.com/tag/algorithms/
This has been an amazing weekend. Pat, Armin and Melanie have done an awesome job getting this started.

Feel free to follow along on Twitter under the hashtagg #24HRstartup

https://twitter.com/hashtag/24hrstartup?src=hash
> What precisely is shitty and broken about gmail's IMAP implementation?

Sent emails for one.

I’ve written various email integration components and have to make special safe-guards for Gmail-specific crap.
Superscalar processors have a deep pipeline with many execution units and keep a lot of instructions in flight so a penalty of a misprediction or stall is significant. Every time it reaches a branch instruction that depends on a result which is not yet available it would need to speculate or stall. Most programs consist of small amounts of compute code followed by a branch that might depends on the results of that code.
I'm surprised that this is only algorithms. I didn't thought that was the main use-case of Ada/SPARK, but rather some kinds of concurrent realtime control applications. I would be interested in seeing examples in that direction.
Eh, telling people to build with brick in earthquake zones is a bad idea.

Of course putting pine trees beside houses in fire zones is a bad idea too.
Yeah, but are you Enterprise sales teams still a complete bag of useless dicks? Yes. Is your pricing still laughable? Yes. Is 'last decades security' still better than handing off internal network control to a third party? Yes. As usual, you only solved how to make Cloudflare more money, and not anything g technically impressive.