skysight-inc/HackerNews huggingface dataset:
> It did when you only had “do you have a cite for this” check my edit

Oh gotcha, sorry about that. I edited my top-level comment fast, so I just assumed you hadn't had time to read the initial version.

> opioid agonism studies especially around addiction treatments where weak/partial agonists opioids are used to ease widthrawal symptoms without prolonging addiction.

OK, I spend 10 minutes Googling. I found a few authoritative lists of addictiveness that didn't seem to correlate with effective dose (which I am pretty confident is the measure of "power" being discussed in the article). And I couldn't find anything that asserted a reasonably robust correlation between effective dose size and addictiveness, whether mediated by agonism strength or otherwise. But I understand if you don't want to spend a bunch of time on this. Thanks.
Changes to the language spec do not have to be backward incompatible. 8 of the 11 Go 1.x releases have had changes to the language spec.
I honestly do not see the point in giving each of my css properties a separate class and then sticking those in my HTML.

If I wanted to do that I would have used the ‘style’ tag.
Every Shakespeare Play Summed Up in a Quote from the Office
I agree with this. FDA approval shouldn’t be the issue since it’s safe when administered correctly and has medical purposes. Controlling distribution should be the issue. There almost needs to by a super controlled substance drug class
Support My Open Source Work by Adopting a Pet Function
ServiceNow and Alibaba.
At ServiceNow, our stack was built on top of MySQL from the beginning. It works for us. We left Oracle® MySQL for MariaDB largely because MariaDB actually seems to work to improve things for its bigger customers.
Also, our SVP of Engineering is now on the MariaDB board.
Interesting: I used to use what you use now, and I gave it up when I realized I was spending too much time re-training, learning the latest UI fads, and not getting any real work done. No consistency, no backwards-compatibility, just the upgrade treadmill. Now that I'm an adult, it isn't worth chasing that anymore, and I'm on Linux now.

Window Maker hasn't changed in a very long time.
The cynic in me think it's very bad press for capitalism. That kind of news is really gold for populists who are against capitalism.

And honestly, how could you really defend capitalism politically? Public opinion does not miss on that kind of thing.
And the other 3 lied
>because, at one point, it'll be in noone's interest to fragment the network

It will always be in someone's interest to attempt to take control of a network, thus eventually causing opposition interest to fork the network, thus continued fragmentation and impenetrability w.r.t. normal users

Basically, how do you solve the "government and/or private individual/group with enough wealth and/or access to resources can take control of a cryptocurrency by acquiring majority consensus" problem?
That title is too long for HN. Sometimes I wish there was a limit longer than 80 characters so that no one has to resort to slightly more sensational titles.
sounds like an ad for hired :thinking_face:
The other 3 in 4 just lie about it.
Why are Silicon Valley execs banning their kids from using social media?
> Auto-injectors have been a solved problem for decades,

And yet we still have stuff like this: https://www.judiciary.uk/publications/natasha-ednan-laperous...

>(3) In the Emergency treatment of anaphylactic reactions Guidelines for healthcare providers the preferred needle length is 25 mm for adrenaline injectors to access muscle in most people. I heard during expert evidence that Epipen needle length was 16mm - suitable according to the UK Resuscitation Council for “pre-term or very small infants”. The use of needles which access only subcutaneous tissue and not muscle is in my view inherently unsafe. An alternative autoinjector, Emerade has a 24 mm needle.

>(4) The dose of adrenaline in Epipen is 300mcg. The UK Resuscitation Council recommends a standard emergency dose of 500mcg. Emerade contains a dose including 500mcg. The combination of what my expert told me was an inadequate dose of adrenaline for anaphylaxis and an inadequate length needle raises serious safety concerns.
Thanks! Though I'm willing to bet this technical parameter isn't what WaPo means by "powerful" :)
EDIT: OUR degrading healthcare* Don't downvote thinking I'm a clueless foreigner...
I agree that there is a difference between deplatforming gab and someone like Alex Jones.

I don't think that any solution is going to be a permanent one, whether it is a law or a technology. I tend to look towards technological advancement to first outpace laws and then the govts slowly catch up. I do think that decentralized storage solutions behind decentralized applications are pretty interesting. There is even something called IPFS which is being pitched as a possible challenger to HTTP. In some of the distributed solutions, the computers holding the data only ever see it encrypted, so the possibility of censorship on that end is mitigated at least for a while. I'm not expert on the topic but I've recently found it very exciting and has given me a glimmer of hope.
> Back in 2000, SJ said that Mac OS X would set up Apple "for the next 20 years".

In the 1990's, he also said that if he ran Apple, he would milk the Mac for all its worth and move on to the next big thing. That was the iPhone, and now Apple is milking that for all its worth, too.

It's not a historical necessity that we ever do invent something bigger and better than "basically a Unix workstation", any more than we need to fundamentally reinvent any of the other foundational technologies of our civilization. A Mac today is a good implementation of a 1980's Unix workstation the same way an airliner today is a good implementation of a 1960's Boeing. Invent a better operating system? Sure, you could also invent a better jet engine or make concrete obsolete if you wanted to, and maybe someone will, but it's been a long time since anybody did.
I've been looking into Java and Go. I don't I like Go very much, it looks too "simplistic" I guess (I don't have much experience with static typed languages though) also its ecosystem seems too young and I didn't like the way it manages dependencies and errors. I've heard good things about C# and it looks cool indeed but I'm afraid I'd have to resort to Windows somewhere down the line and, I'm sorry, I think Windows us unbearable. What else could I look into? Is Java really that bad? I'd like to write Rest APIs, GraphQL servers and stuff with websockets mostly. Also does anyone here have tried that Micronaut Java web framework? It seems cool but everybody talks about Spring. Thank you all.
Botox is lethal at ~1ng per kg of body weight. It takes 20,000 times that amount of the compound in question to kill you. (These are both using LD50 numbers).
Alternatively just one statistician lied, the one conducting this study.
I am right there with you! I am oddly excited by the recent waves of de-platforming. I think they are hastening the next step of development.
I'm using WCF on .NET Framework. The whole enterprise stack is still there.
Yes, anything you can do on quaternions you can do on rotors. (Updated the article)

I have not seen a clean version of the code online but it is almost the same as for a quaternion.
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Unit quaternions are isomorphic to rotors, so there’s no practical difference between the two. The difference is how you introduce the concept of 3d rotation: the “traditional” way is to introduce quaternions with i^2 = j^2 = k^2 = -1, and then do some handwaving to convince the reader that they are good for 3d rotations. The bivector formalism is more natural and needs no handwaving.
Interesting. I'm a bit confused about slide 6, which says that it has a theraputic index which is 100 times better than fentanyl. It cites the reference [1], which indeed has those numbers in it, but the full table there is:

ED50 LD50 Theaputic Index
Fentanyl 0.01 3.1 277
Sufentanil 0.007 18 26716

The therapeutic index is the ratio of LD50:ED50.

This clearly makes no sense, someone must have moved a decimal point, and got a number which is wrong by a factor 10.

EDIT: Ok, it seems that it is indeed an error in the cited paper, but the typo is for the ED50 number. In the original source[2] it's given as 0.00071, which agrees with the "10 times stronger than fentanyl" claim in the original article, and gives the correct theraputic index.

[1] https://onlinelibrary.wiley.com/doi/abs/10.1111/j.1440-1681....
[2] https://twitter.com/davidjuurlink/status/859227636400349184?...
Yes, that was a response to "Science should be subject to logic and reason" etc. To your hypothetical example, I think Hitler's reputation is pretty low right now and it's not necessary to deny him citations just so he won't get more cachet. Her article was about professors who are "jerks", "whose academic sexism hasn’t risen to the level of actionable correction".
thanks for this!!
I think it is a major flaw to assume someone's conspicuous consumption is from YOUR money.

This man has been in crypto for 8 years

Anyone that was there for the last 15 months could have made enough FROM SCRATCH to buy those things just trading. I've had hundreds of dollars of DUST in exchanges and wallets that I rediscovered were worth 6 figures, and at some points 7 figures if had checked. Even if the government had frozen some of my assets in connection with blah blah blah, I'd still have this stuff.

Add in advisory roles, salaries, the conference circuit, you might as well just fire your lawyer for coming up with that children's tale, and just stick to why someone might owe you money not "and here's proof they're the bad guy we must stop him NAO!"
Or you can just literally record it with https://asciinema.org/ and embed like a video. The text will be selectable even!
Meant to put "through DirectX" where I put "through OpenGL". Thanks for catching it.
Kickoff Kit: Tools to Help Teams Work Better Together
That's a cool idea, I'll try that. Thanks!
Yeah, the kind of landlord that designs its own CPUs, GPUs and co-processors, has its own language (Swift), solves several difficult engineering problems with every new product, and so on.

Meanwhile, since I was watching Apple in 2000-2007, when they "used to be an inventor", they used to put out barely incremental updated for the iPod, the OS, and Mac laptops every year.

People would circulate rumors for months, and then cheer, for tiny generational spec updates on iPods. Now we get 10x the technological change we got every year of that era between iPhone models, and people are blaze about it.

Also, Google aside (and them only on the software assistant side) who solves any interesting consumer problems in the space Apple works?
The title can be misleading if it is not read literally (or your brain tries to fill in extra information). This is testing the effects of gravity on antimatter, NOT antigravity testing.
How to Save Globalization: Rebuilding America’s Ladder of Opportunity
First off, I just want to point out that the federalist is an extremely biased source. That doesn't make their arguments wrong, just biased.

Second, there are anti-Semitic behaviors by people across the political spectrum. The far right is, mostly, worse. Large numbers subscribe to extremely racist theories and people do outright call for the extermination of the jews.

Third, the right likes to connect anti-Zionism or opposition to the current government of Israel to anti-Semitism. This is ridiculous. The behavior of the current government of Israel has been criticized, to varying degrees, by every other government on Earth. The left (not liberals, the actual left) largely sees the government as nearly fascist and pushing the idea of an ethnostate. That's not because everyone on the left hates Jewish people, it's because Israel's policies support that idea. The right pushes the idea that Israel is America's closest ally, that you need to support Israel unconditionally, that we should have laws against movements like BDS, and that if you criticize Israel it's anti-Semitic.
Of the less serious offenses, 55% of biostatisticians said that they received requests to underreport non-significant results.

Sigh.
awesome! thanks for sharing :)
Multiple implementations for abstractive text summarization
I have been using Nix for about 2 years now at our company and its pretty amazing. In my experience it doesn't make compiling things much easier than normal, but the difference is that once something builds, it just works. ALL THE TIME. In previous companies I spent a ton of time debugging other devs environments that worked fine on my machine, but cause linker errors, breakage due to transitive deps, slightly different compilation artifacts, etc. Furthermore most tools are language specific leaving you to fend for yourself to get the system dependencies or rely on a separate binary distribution package manager. Nix handles everything we throw at it, we have even configured our dev env to roll to the new nightly Rust every week without any effort from the developer. We also get the performance benefits of compiling everything with march=native. Additionally our dependencies and dev environments are cached, so most of our engineers never have to wait for things to compile. The issue we have ran into is due to the fact we are running a traditional distro instead of NixOS, which causes headaches when your code depends on a kernel module (Nvidia drivers for example) or you want to register systemd units. This has led us to have some hacks in our setup to make it work. Ultimately we are thinking of just making the transition to NixOS. Its unbelievable to me that I can deploy an entire mesos cluster with just two lines of code.

FWIW if you enjoy Nix and are interested in using it in production feel free to reach out to me.
brandon [at] standard [dot] ai
Could 'Oumuamua be an extraterrestrial solar sail?
This is patently false. There is a stable release every six months, and a team dedicated to patching the stable release. I'm surprised you missed this, as it's right there in the first sentence of the download page: https://nixos.org/nixos/download.html

You have the option of following the master nixpkgs branch, or one of several "channels" which are essentially tested checkouts of the main nixpkgs repo. There are both stable release channels (i.e. nixos-18.09) and unstable channels (i.e. nixos-unstable).
Comments are now implemented!
Apologies. I started reading, realized I had no idea what this story was about and ended up reading the background story linked by empath75. By that point I was fuming and back here writing my comment. RTFA fail.
There reminds me of a recent 99% Invisible episode [1] in which they discuss the same topic in the world of dinosaurs. It details how dinosaurs used to be depicted with the goal of only showing the things that we are confident in being true (although what we are confident in obviously changes over time). This results in mostly just greenish-brown skin draped over a muscle structure attached to the fossilized skeletons.

In recent decades there has been a push to show the animals more realistically. The fossilized evidence is studied and compared to the skeletal structure of animals that exist today. Inferences and educated guesses are made from there to project a more realistic but more subjective image of the dinosaurs. We now get much more varied and interesting depictions with feathers, bright coloring, fat deposits, and other features that can neither be completely confirmed or ruled out based on the evidence.

[1] - https://99percentinvisible.org/episode/welcome-to-jurassic-a...
The FDA approves things based on the purpose they were presented to the FDA/market for.

It isn't based on danger, it is based on evidence backed disclosure of the danger.

In the specific use the company told the FDA about, it passed, and that will usually happen with some objections or outright denial. The denial didn't happen and that isn't article worthy.
Don't get rid of Apu. He's a hero to many of us
Exactly this.

I've made four attempts to consider an Android ecosystem and have owned the following:

Nexus 4, Nexus 5, Note 5, and Pixel 2XL.

The Nexus/Pixel phone hardware were fine, but I found that the software ecosystem was heavily lacking. I got the impression that to the majority of Android devs, UX was the last thing they cared about.

The Note 5 on the other hand was one of the most disrespectful, anti-consumer experiences I had ever encountered since ditching a dumbphone years ago. The carrier I used (Verizon) felt it was appropriate to plaster its own logo on the back of the phone and in a loading splash screen when powering on the phone, plus preload the phone with a bunch of useless apps that could not be uninstalled.

Every single time that I've purchased an Android device hoping that it was finally good enough, I've ended up carrying my iPhone as a secondary device within a week and either returning or throwing the Android device in the drawer within a month.
Also: stop conflating bivectors and vectors. E.g. the inverse-transpose rule for transforming normal vectors needs no explanation when you treat them correctly as bivectors, and not vectors. Same goes for torque, etc.
No they didn't. In the two situations he is clearly alluding to

1) the person admitted it was hurtful and unacceptable and that they should not have said it, and the mainstream publisher said they would not have hired her without this understanding

2) the argument the person made before being fired was not simply that there is a non-zero amount of sexual dimorphism in humans, it was concretely that womens' neuroticism, agreeableness, and other feeling-sy tendencies may explain why they are on average worse leaders, underrepresented, underpaid, etc.
If you compare the tone of her hand to her face in the black and white image you can clearly see that the colors are different.
yeah :/ that's just sad
I think the suggestion to remove the kids' computer arises out of the expected likelihood that the kids will just load up Facebook, YouTube, Twitch etc. and install Steam, and never engage with anything other than those activities.

When I was a kid and I spent hours on the computer, none of that stuff existed, and it was difficult _not_ to learn interesting things because the primitive nature of the computers forced me to figure out a lot of non-obvious things. I wanted to play computer games too, but sometimes I had to figure out pretty advanced troubleshooting processes to even launch a game (for example).
I wonder how prevalent this sort of thing is in other fields. I also wonder how prevalent fraud is generally, and the extent to which it is driving our decreasing faith in the academy. Also, how much (if any) of this fraud is motivated by political (instead of strictly personal) outcomes.
I've yet to see a product that requires that. Let's compare Apple's devices against devices that actually exist instead of terrible devices that exist only in fantasy.
I spent a couple months implementing a promising optimization technique that was published in Nature. I assumed that I was missing something or had a bug in my code because I could not reproduce any of the results. It turns out, one guy in my research group knew the author. He requested the source code for me to the program used to generate the data for publication. That program did not even come close to doing what the paper claimed due to some very serious bugs. When I brought up these issues, nobody really seemed to care much. It wouldn't be worth anyone's time to try to correct the issue or write to the journal.
The logo has the username as well. I assumed it's to prevent people from copying and taking credit for other people's work. (That said, I do see these videos with the logo cropped out)
The other problem with fentanyl is that it is much "stronger" than morphine, and much easier to smuggle into the US. It was until recently legal to produce it in China.

This means heroin dealers were buying fentanyl and cutting it with sugars.

If they correctly cut it - dilute it - it's bad, but not as bad as when they incorrectly cut it and release product that is too strong. This is one of the reasons fentanyl is killing so many Americans.