skysight-inc/HackerNews huggingface dataset:
Genentech | Data Science, Imaging | South San Francisco, CA | Full-time | Onsite

https://www.gene.com/careers/detail/201808-117349/PHC-Data-S...

The PHC Data Science Imaging group seeks a talented and motivated Imaging Data Scientist to join us in supporting the efforts of the Personalized Healthcare (PHC) Group. To aid in the development of novel imaging biomarkers in PHC and their potential use in clinical drug development, the RWD Imaging Group at Roche is responsible for generating and executing plans to: (1) curate and analyze clinical imaging data from Roche’s late stage (Ph3) clinical trials, and (2) devise plans to gain access to (and analyze) clinical imaging data from a RWD setting (e.g., health registries, hospital systems, etc.).

The position requires extensive cross functional collaborations working with a diverse team of clinical subject matter experts, data- and imaging scientists, statisticians, and IT staff. Your responsibilities will primarily support image analysis efforts within the group, focusing especially on applying Machine- and Deep Learning approaches to oncology-, neuroscience-, and ophthalmology projects. In addition to developing and applying novel, data-driven approaches to solving RWD image analysis challenges, the position requires the Imaging Data Scientist to work closely with clinical imaging data management group to deploy, maintain and integrate computational solutions. The job will utilize and build on your experience in scientific/medical imaging, data and image management, application of novel statistical and machine learning approaches to `big data’, software development, and scientific data transfers.

Responsibilities:

Collaborate with internal imaging- and data scientists and external vendors to derive and validate novel imaging biomarkers in support of clinical drug development and RWD evidence (payer support) generation.
Identify and gain access to external RWD imaging data sources.
Curate/clean/organize large and messy clinical imaging datasets.
Identify and support imaging data management solutions within PHC.
Continually search for opportunities to automate workflows and streamline processes.
Support and contribute to the development of advanced analytics and computational tools.

Required skills:
Proficient in at least two scripting languages such as Python, Matlab, R, Perl, etc.
1+ years of data science experience.
PhD or MS in quantitative field (eg mathematics, statistics, computer science, EE, etc.), and/or adv. Life Sciences degree with significant computational experience.
Documented experience with Machine Learning, Deep Learning, and statistics.
Solid understanding of medical image formats (ie DICOM).
Experience with database applications.
Excellent communication skills.
Ability to multitask and prioritize while maintaining efficiency and quality of work.
Internally motivated with a commitment to accuracy and quality.
TSViz: vis­ual­ize executions of complex multi-threaded systems
I would think that fighting, alochol and other drugs are being consumed by 6 hour sleepers during the two hours that the 8 hour sleepers are... asleep.
I can be convinced when the argument is good. I don't think a nebulous, "give up your privacy for some possible safety gains" is such an argument. I equate privacy with freedom, and I don't want to give up my freedom.
But the margins are already much lower on the smaller dies.
Already something like a quark is next to free on the process level; the recurring cost is nearly all packaging and testing.
Additionally there's some practical limits to how small you can make a chip since you still need the analog side of the io pins and their bond pads, and you can't shrink those very much.
That's interesting, and we'll see what CA gov does and how far the CA politicians think they can go with this. If they mandate simply that Khosla must ALLOW access, how much can/will he charge for that access, lets say something stupidly large like $200? Would he be within his rights to do so?

And since it is his property, he should be able to close the parking lots, bathrooms, and general store too, especially if he were to be liable for maintenence, upkeep, accident liability, etc?
Apple has absolutely no desire to go into the device management business. They make the devices, they don't provide IT departments with any in house tools, the entire macOS management ecosystem has risen from a need and it's a mish mash of different vendors / open source tools / approaches to skin the cat that is device management.
Aura | Backend Engineer | New York or SF | Full Time | Onsite | https://boards.greenhouse.io/aura/jobs/4090425002

Aura is a smart picture frame for sharing photos with your family. We make the hardware and the software for it, and are hiring a backend engineer to help us scale.

You will work directly with the CTO and other senior engineers to identify, prioritize, and execute on the most impactful projects for the company.

Our backend systems power a network of thousands of picture frames across the world to deliver cherished family photos - the right photo at the right time. We apply state-of-the-art computer vision and machine learning technology to thousands of photos every day to automatically sort and curate our users' libraries. We have experienced 300% year-over-year growth, and the scale of our network will continue to grow in the future. There is a seemingly endless supply of challenging new problems - new scale, new technologies, and innovative new product features.

Our technology stack is built on a combination of Ruby on Rails and Python. Everything runs in AWS, utilizing EC2, S3, CloudFormation, SQS and other services.

Email bcherry@auraframes.com directly to apply.
What does it mean that the ask is written in NASM/GAS syntax? Those are two wildly different asm syntaxes with different macro languages etc.

Is some asm written in one variant and some in the other, or is it all written both ways? Maybe for some targets GAS is used and others NASM (<-- it's this one as answered below)?
We did not try their PPC listing. Just keeping our profile up-to-date and ask our customers to share their experience about us there.

I cannot measure impact directly, but I think it worth my time to maintain a good looking profile at a resource with estimated monthly visitors = 7.4M (according to SimilarWeb).

Also, if you search for example "best time tracking software" in Google, they are on first page. And it costs $0.
I see no reason people wouldn't respond rationally to the extra incentive to cheat on their taxes, given that they have enough money for their tax evasion to matter in the first place.
There are HN readers who are Directors of IT at their place of employment
This isn't about the beach itself, it's about whether he's obligated to keep open (and presumably maintain) a private access road that runs through his property. If the state wants to keep the road open, they should negotiate an easement and maintain the road themselves -- it doesn't make much sense that a property owner be obligated to provide a road for the public without some sort of compensation.
Unfortunately your views are fundamentally opposed to what most people (at the very least here) would define as freedom and civil rights.
You shouldn't use Python 3.7 for data science right now
No, it’s really not - you’re either forgetting or are unaware of payroll taxes, insurance, etc. not to mention rent, electricity, capital expenses, and every other expense needed to run a business come out of that $1m.
You mean the IRS pays for wars.

"The roots of IRS go back to the Civil War when President Lincoln and Congress, in 1862, created the position of commissioner of Internal Revenue and enacted an income tax to pay war expenses."

https://www.irs.gov/about-irs/brief-history-of-irs

> You are the middle class! I'm helping you!"

What do you expect someone working for the IRS to say? They are unconstitutionally robbing the middle class blind?
A Review of the Recent History of Natural Language Processing
Unboxing of the Mi Band 3 – Review
Obama was under the illusion that he could reach across the aisle and work with the Republicans, and tried very hard to do something that both sides could support. I think he didn't realize yet that making sure your side has wins, and the other side has losses, is how the game is played now at that level.

So after all that, he got no Republican votes. Even thought the plan was, at it's base, a conservative plan. He was naive.
Profile manager / MDM on MacOS Server is a goddamn nightmare.

It's amazing when it works, but when it breaks you're SOL. Case in point is I inherited a semi-broken system when I started my job 3 years ago. ~40 enrolled laptops but couldn't add any more. Peeking into the logs the SQL server built into the .app bundle broke/corrupted.

Many others in the Apple forums had the same issue but no resolution and the solution ended up being "flatten and reinstall".

For a small business, sure Profile Manager might work, but scale beyond 10-20 users Jamf Pro is the way to go.
In case your hands are..well, tied, another alternative is saying “hey Siri, whose phone is this?” - pulls up your contact card and disables biometric unlock.
Proton Technologies AG | Network Engineer/Storage Engineer | Full-time | Geneve, Zurich, San Francisco | https://protonmail.com/careers

At ProtonMail, we are committed to online security and privacy. We have been working diligently on this cause since 2013, and we launched ProtonMail in 2014 with the goal of defending our rights to security and privacy online.

Today, ProtonMail is used worldwide by millions of business professionals, journalists, activists, and individuals who value security in their communications. We strive to make encryption and privacy an integral part of the future of digital communication. Along the way, we are developing and building cutting edge technology to support our rapidly growing community.

Proton Technologies AG is an international company headquartered in Geneva, Switzerland, with a presence in San Francisco, Macedonia, France, Czech Republic, and Lithuania. You will find among us former CERN and MIT scientists, chess champions, and many experts in their fields.

For those up to the challenge, ProtonMail provides an intense and exciting atmosphere as part of one of Europe's highest profile and fastest growing startups. We're looking for extremely intelligent and highly motivated problem solvers to join our team of experts. We provide highly competitive compensation packages, commensurate with experience and performance. As a fast growing company that doubles headcount annually, there is also the possibility for rapid advancement for capable candidates. We operate on a strict meritocracy, with a flat management structure, and promoting internally whenever possible.

ProtonMail has millions of users, and we are growing rapidly. As part of our team, you will have the ability to make a direct and significant impact. You will have the chance to work on challenging large scale problems related to scaling, security, reliability, and user experience. Our work is complex, and our team moves fast and works at a higher level than the typical team. You should be smart, fast, versatile, and creative. Working with us will likely be your most challenging job, but perhaps also the most exciting and rewarding. In the process, you will touch the lives of millions of people around the world.

We currently have several openings, and in particular we are looking for Network Engineers and Ceph Storage Engineers.

Our technology stack is built on top of PHP, Javascript (Angular/React), and we have desktop client in Go, and Android and iOS apps. We also employ Ansible/Puppet, Elasticsearch (ELK-stack), and Kafka.

See https://protonmail.com/careers for more information and to apply.
It kinda does, it's called greylisting and already works today: the recipient basically says "can't right now, please come back later". A spammer will not bother even reading this and will hit other targets. A proper smtp sender that dutifully respects the specs (the legit ones do) will try again up until a few days later, where the recipient can whitelist the sender.

It's all automatic so it kind of doesn't solve OP's issue, but I feel like there should be a proper way to handle the challenge-response part.
Anyone can get a push certificate, it's not just businesses,

https://identity.apple.com/pushcert/
Looks like it doesn't work. Or I'm doing something wrong :(
this comment made me sad. i am a south asian national, i do have a canadian tourist visa and was hoping to go watch F1 in 2019 in Montreal. reading all of this is probably going to change that plan :/
Possibly soon. Some awards that Allison/Honjo and CRISPR researchers have both won recently:

Warren Alpert Foundation Prize: Allison, Honjo et al. (2017). CRISPR researchers (2016).

Tang Prize: Allison, Honjo et al. (2014); CRISPR researchers (2016).

Albany Medical Center Prize: Allison et al. (2018); CRISPR researchers (2017).

Gairdner Foundation International Award: Allison et al. (2014); CRISPR researchers (2016).

Gabbay Award: Allison (2011); CRISPR researchers (2014).

Breakthrough Prize in Life Sciences: Allison (2014); CRISPR researchers (2015).

That doesn't mean they'll win the Nobel, but they're definitely in the same awards realm recently. It might be Emmanuelle Charpentier, Feng Zhang, and Jennifer Doudna.
The article wrongly conflates Noble Group - an unrelated Hong Kong company, trading commodities, with Noble Bank - the actual Tether bank, having rumored problems.

The Hong Kong financial group - the one that is being bought by Deutsche Bank - has nothing to do with cryptocurrency. (That means liquidity problems of the Tether bank cannot be related to commodity trading.)
This is 100% destroying the phone for younger generations ... my kids answer nothing, not even my own phone calls because they set their phones on do not disturb to curb the endless robo, scam, and cold calls.

If it wasn't for https://hiya.com/, I'd be at the end of my wits. Seems like the number of fake calls has ramped up exponentially in the last months. I finally just set it up completely block all telemarketing, spam, scam, fraud calls.
What is the implication to ad blockers as a whole?
If you were under medical treatment for your depression (hopefully you were), just say that you had a medical issue, the treatment helped you recover, and that you spent part of the time recovering studying independently. Be prepared to provide a note from your therapist/doctor that provides the dates you were under treatment to back up your words but note it does not have to describe the issue you were treated for or the treatment. If pressed about the specifics, know your rights (Google around for info on what employers are legally permitted to ask about medical conditions), remind them of those restrictions, and be prepared to write off that employer if they persist.

Resign yourself to the fact that you're going to have a long, difficult road ahead if you want a programming job. Being from a non-traditional background, you're going to really have to shine at the interpersonal and coding side of interviews to persuade a company to hire you. Use study guides for both aspects and try to attend local tech meetups where you might be able to persuade a working professional to give you interviewing tips.

Persistence almost always pays off. Good luck to you.
The IRS literally did admit to abusing its power in 2017 https://www.npr.org/2017/10/27/560308997/irs-apologizes-for-...
Dupe.

https://news.ycombinator.com/item?id=18112830
> _always_ verify and call the number back

Fine in principle, but banks do call, and often have no direct dial, as a matter of policy, for whoever you're speaking to.

So it becomes verify the number, call back, and spend 30+ minutes in a queuing system before some lowly call centre worker on another continent incorrectly tells you they can't connect you to the xyz department.

It used to work before call centres and all the small banks became just branding on the front of one of the big 4. You were even allowed the phone number of the local branch! That's the UK market btw.
Indeed. I don't know where this strange desire of his to show off how big his wristwatch is has come from. Part of the stability of the public market is due to the good behavior of those who participate (such as it is - c.f. crypto for the counter-example). Musk's continued juvenile behavior is doing the investors of TSLA, whether long or short, no favors. The BOD needs to hold a come-to-Jesus meeting - if Musk holds too many shares for that to be effective, then the SEC needs to step up its game - or just let the "naughty" behavior and loss of investor confidence and lawsuits continue.
Hi, I'm the author(along with several other developers).
MicroMDM is used in some enterprise environments and was recently mentioned in a number of security presentations regarding Apple's MDM and Device Enrollment Program services.

https://duo.com/labs/research/mdm-me-maybe
https://i.blackhat.com/us-18/Thu-August-9/us-18-Endahl-A-Dee...
Those missing 2 hours of sleep are probably from going to bed 2 hours later, though, which is a pretty specific time.
Arcesium | Distributed Systems Engineer | Software Engineer | Software Engineer Intern | New York, NY | Onsite | Full-Time | Visa

Arcesium is a post-trade technology and professional services firm. We offer a new way for hedge fund managers to scale their business while maintaining control of critical non-investment activities. Arcesium combines a comprehensive and fully-integrated technology platform with a team of experienced hedge fund professionals to solve the most complex post-trade challenges of asset managers. From real-time integration with order management systems to robust and automated oversight of third-party administrators, Arcesium offers managers an elegant, unified, and expert solution for their entire post-trade process.

Arcesium is hiring for the following roles:

- Distributed Systems Engineer
- Software Engineer
- Software Engineer Intern

To learn more about these positions, please visit our Careers page: https://arcesium.com/careers.shtml#careers.

To be considered, please send your resume to careers@arcesium.com.
For those of us not well-versed on Italian proverbs, would you tell us what that proverb says?
Hacktoberfest 5: Support open source and earn a limited edition T-shirt
The article has no details, and there is no explanation about how a blockchain may solve any of the problem. I's just appeal to magic.

(Also, what are the problems? There have been borders with different money for millennia.)
Wow what a racist piece of shit.
MDM push notifications require to be signed by a special certificate, which is only available upon request.
I was a bit appalled by his recent behavior but I must say the good largely outweighs the bad when speaking of Elon Musk. We need more, not less, people like him who dare shaking things up and dreaming big. I really think that if EV start taking off it is mainly to his credit, he put legacy car manufacturers on notice and left them scrambling to evolve from diesel to EV.
Sourcegraph (https://sourcegraph.com) | Software Engineer | San Francisco, CA or REMOTE

Sourcegraph is building tools that software developers love and use on a daily basis. Our code search allows you to instantly search across all of your company's private code to find what you are looking for (definitions, examples, error messages, etc.). Our browser extensions give you IDE-like code intelligence (e.g. hover tooltips, go to definition, find references) while you are looking at code in your browser, on Sourcegraph, or on your code host.

We are a small team of mostly engineers who love to code, and we already have big/recognizable/global companies paying for our product. If you are passionate about making the world better through software, come join us!

Stack: Go, TypeScript, GraphQL, Docker + Kubernetes

Jobs page: https://github.com/sourcegraph/careers/
Here’s the related WSJ article:

https://www.wsj.com/articles/the-qwerty-days-are-almost-over...

The author is basically making the case that with AR, VR, and mobile devices, we need another input device instead of a keyboard.
Which is public knowledge as soon as it hits mainstream news.
I read it cover to cover out of a sense of obligation but came away very disappointed. The Achilles-Turtle-Random Other Creature allegories got very tiresome, and the content took a very long time to get to the point. For anyone interested in the proof, I recommend Gödel’s Proof by Nagel instead. It covers the same material in about a tenth the space.

(GEB has other philosophical discourses that are interesting, if only as an example of how people can very reasonably mispredict the future. In Hofstader’s case, he posited that chess would only be played at a human level by an AGI.)
Ask HN: Anyone else having problems with delivery of Lily-NG / Mota group?
I bought a Lily-NG from lily.camera in June. It has now been 100+ days without a delivery.
Their support is not responding at all (first contact at the beginning of September with weekly follow-ups).
I've filed a complaint with their BBB, but they responded with just a "We'll look into it"

Anyone else having these problems?

Sad to see that the scam continues under new management
That is ignoring the enormous externalized costs. I have known business to have spent hundreds of thousands of dollars in professional services when being investigated that have done absolutely nothing wrong.
Bolivia sea dispute: UN rules in Chile's favour
The same can be said about speeding tickets, that money spend on enforcement comes back. But tax collection isn't business. This is law enforcement, or at least enforcement of laws. We shouldn't judge it on its profitability. Like speed enforcement, it is something that has to be done not just for those who are caught, but to deter all the others who probably won't be caught.

There are evil implications should we judge the effectiveness of tax collectors purely on the basis of cost/gain. We don't want a situation where the IRS only ever goes after easy cases. The people who hide the most money have, by definition, the resources to hide it well. If you want the IRS to go after the big fish, they need the budget to do so. We don't want them resorting to drift-net tactics, only scooping up the easy/small fish.
I'd be curious on your thoughts on this:

I have an undergrad in Computer Engineer, grad in EE from a big state university.

My employer is willing to pay for another Masters (nice perk...). I have 10 years working experience and work in Atlanta now - so I can do the Georgia Tech Executive MBA, or, their online Computer Science degree.

Assuming I have time (have a 2nd baby on the way so debatable)...and it's free. Is one more worthwhile than the other. And although the G. Tech online degree is available for free, the pressure of deadlines would actually ensure I complete the courses and not just watch a few hours and stop...like I've done already.
Just to clarify, where in this thread was increasing it's budget discussed? The statement above pertains to current spending levels and it might be that the next dollar of budget put into the IRS yields $.90, but currently the IRS is assuring laws are obeyed while netting a gain to the US government. The only justification of cutting their balance (from a purely profit driven angle) is if the suspicion is that the first half of the budget to the IRS pays $2.40 per dollar and the second half pays $0 (or some similar less than dollar ratio), but this seems like a quite straight forward win.
It's not clear to me where the line between obfuscation and minification is here. Minification is a form of obfuscation. Transpilation and minification also make code significantly harder to review compared to the original code so I'm not following the rational behind this.

Firefox/Mozilla require you to submit the original source code for review for example (minification is not allowed): https://developer.mozilla.org/en-US/docs/Mozilla/Add-ons/Sou...