skysight-inc/HackerNews huggingface dataset:
Broad Institute of MIT and Harvard | Cambridge, MA | Software Engineer | ONSITE, VISA

We are a small team of software engineers, computational biologists, clinicians, and geneticists building cutting-edge tools and methods for interpreting the largest public dataset of human genetic variation ever assembled: currently ~200,000 individual human genomes/exomes and approaching 1 million over the next few years. We aim to determine how genetic variation alters our proteins, biochemical pathways, cells, tissues, physiology, and traits/susceptibility to disease.

Position 1: Work with a team of genome analysts to develop software for solving real genetic disease cases. You should be excited about the engineering challenges associated with loading, searching, deploying, and visualizing huge genomic datasets stored in the cloud. Your work will directly help thousands of kids/families find the root causes of rare genetic disease.

Position 2: Are you interested in understanding how human traits are associated with genes? This role involves building an interface for scientists to browse through thousands of human phenotypes and explore regions of the genome that are associated with these phenotypes/traits. We are looking for a brilliant data visualization engineer that can synthesize multiple datasets and craft performant, beautiful, and useful web applications.

Technologies we use: React, Redux, Python, Docker, Elasticsearch, Kubernetes, Google Cloud. We are looking for friendly people with demonstrated experience in web tech, an eye for design, and genuine interest in learning new things. We are supportive of candidates interested in transitioning to graduate school. Your work will be 100% open source and highly visible in the genomics community. You will shape the way scientists interpret human genetic variation.

Email: msolomon@broadinstitute.org (conversations will be kept confidential. We now have an application tracking system in place so you will be notified about application status).
There is a pretty strong power law in effect for the ROI on an MBA depending on the strength of the school. https://gmatclub.com/forum/value-of-a-top-10-mba-213365.html
>Many of the people I know who are proud of quitting Facebook are happily snapping pictures daily for Instagram or chatting regularly on WhatsApp.

If you are implying (through the use of "proud of x, [but] happily doing y") that this is some sort of contradiction, I challenge that implication. WhatsApp and Insta are entirely different products by the same company, which scratch different itches. Not everyone changes their social media habits based on a perception of moral failing by the company that purveys those services -- that appears to be something rather unique to a subset of individuals. Some people just want to be happier.
I don't really get this. How is any language's stdlib _not_ someone else's work? The language itself is "someone else's work".

The only difference, in my mind, between a "standard library" and a "third-party library" is the level of trust. If a third-party library is widely used by a community and known to be built by trustworthy people, I don't see how it's functionally different from a "standard" library.

EDIT: To clarify, I'm only trying to make a general statement about libraries, not the trustworthiness of any particular language's library landscape.
> A lot of them are quite ignorant about engineering and scientific basics.

Yes, they are, but you don't see a lot of MBAs sitting by a coder's desk and saying that they're choosing the wrong name for a function.

[Edit: added quoted text]
I would say "don't go to Canada", but I'm not sure how common this is across the world.

The more you travel, the more common it is.

The phone thing is somewhat new, ever since certain companies started selling devices to governments that let them crack, examine, and archive your phone.

But being hassled at the border has always been a risk. Before it was terrorism, it was drugs, or just the change in culture.

I've had problems getting into Japan because of my heart medication.

I've read that if you have stamps in your passport from certain Middle Eastern countries, you can't get into some other Middle Eastern countries.

I've also read quite extensively recently that it's become very difficult for Indians to get into Georgia. Entire families, and even planeloads of people have been turned away, if you believe what you read on TripAdvisor.
That's a fair point but in my experience in these situations the controversial bullet point would be pointed out by the top upvoted submission when you open the comments so it's only one click away anyway. I hope that people on HN don't upvote/downvote stories based solely on their titles, and if I see an upvoted story whose title is "PopularSoftware v.6.2 is released!" I'm definitely going to check what the people have to say in the comments.

I mean you've been here for quite a while judging by your profile, do you really find this to be a practical problem while browsing HN? Personally it's really a non-issue and the potential slippery slope of letting people come up with custom submission titles is not really worth it IMO.
Why would you have to not work for two years?

There are plenty of executive MBA and part time MBA programs from reputable schools (not just for profit and online schools) that would allow you to work and go to school. There are some that only meet on weekends.
Remember kids, this is what we get as long as we support the War on Drugs.

It's not about "I just want to get high", it's about removing insidious incentives for the destruction of democracy.
BadCode – Bad art competition and an educational tool
I assume it is still the case that most of the top programs strongly favor candidates with full-time work experience. (Both because they have more context and can share those experiences and context.)
I have an undergrad finance degree + finance career. I also run a website I built my self as a side project (see profile if curious).

For a while after learning to code, I thought my business degree was useless. My coding skills felt so empowering compared to my finance/business skills. I can create with coding... learn and do. A car mechanics certificate felt more useful than a business degree.

Over this period of introspection, I started paying attention to whenever my business/finance knowledge was actually useful. I very quickly realized that very smart people often have very little knowledge of finance and business. Business knowledge that I assumed as common sense (due to being surrounded by other finance people) is completely enlightening to others. With a business degree you learn how the world works, which is very important to anyone who wants to be entrepreneurial.
Privacy Shield – Granicus – Privacy Information and Data Collection Policy
I'm surrounded by people – but I feel so lonely
https://en.wikipedia.org/wiki/List_of_Super_NES_enhancement_... would have made it difficult to do this on the SNES, especially for great games like Yoshi's Island that took advantage of this.
Sounds like a subject from a spam email. James Veitch - would reply “I’m in.”
You contradict yourself when you talk about the issue not being one of terminology when you say the opposite by saying a `regular` rifle is a bolt action rifle when the most common retail rifle sales are of magazine fed semi-automatic weapons.

Please come back with an internally coherent argument, and then we can start from there.
They did post a writeup here: https://newsroom.fb.com/news/2018/09/security-update/

Although, I expected to see a notice after my own tokens had been reset by Facebook before or after logging back into my account.
Apparently it was an evolution of Sol, which wasn't designed for programmers.

You'd think that everyone in computer science would have read https://www.cs.utexas.edu/~EWD/ewd08xx/EWD831.PDF by now, though. Makes a fairly airtight case for zero-based indices.

I've noticed that in functional languages, the presence of enumeration operators makes indexing in any case almost entirely unnecessary. Perhaps the original problem was just a "design smell" all along.
couldn't get working on touch screen.

biggest problem I see is that it projects a misleading vaneer of precision. Others might take it too literally. Suggestion: use cartoon-like graphs/fonts to convey idea that these are back of the envelope projections.
And if their resume points that out they get an interview. As I said in another comment, if you show up with a junior position, no degree, and shit to show for it on Github or somewhere else...I don't have time to interview you in a pool of 500 applicants.
Engine ML | San Francisco, CA | Business Operations Manager | Full-time | ONSITE

# About the company

- Engine ML is a platform for building deep learning applications faster and at a lower cost. We give your engineers their own state of the art GPU cluster for training models — reducing training time on average by 30-50x. Engine ML helps your engineers easily detect performance bottlenecks, share results, and implement deep learning best practices — saving your company time and money. Our platform does the work of an entire infrastructure and devops team, so your engineers can focus on building your company's core product.

# Responsibilities

- You will be responsible for onboarding new customers, negotiating contracts, driving adoption and retention, and ensuring ongoing satisfaction. You will work with our customers’ C-Suite executives and senior managers to bring to enable them to achieve their goals using Engine ML.

# Experience

- You have experience successfully bringing an early product to market. You have experience negotiating contracts with customers and vendors and managing legal teams. You have built financial forecasting and pricing models for software companies and have excellent written and verbal communication. You are a fast learner enjoy working with technical teams.

If interested, email will@engineml.com
You can think of a system in which farms are just not built in places with potential water scarcity, but built to use renewable water sources for their plant growth.

My point: If you build a company in a location which is unviable in the long term, should you be subsidized as to not move to a more viable location? I think such subsidies are unviable in any but the short term, and are counterproductive for every other party involved.
Syllable Life Sciences | Cambridge, MA | Onsite Only

https://angel.co/syllable-life-science/jobs/

Or send a CV to us at: jobs@syllable.life

Syllable Life Sciences is a Cambridge-based biotech company using machine learning and computer vision to automatically decipher body language in humans and laboratory animals.

We're hiring for a lead data scientist to work on challenging problems at the intersection of drug discovery, behavioral analysis and Bayesian statistics.

Our platform is in use across the world at pharma companies, helping to develop better drugs for diseases like ALS, Parkinson's and Alzheimer's. Check out the video accompanying our peer-reviewed publication for an explanation of the technology.

https://www.youtube.com/watch?v=Yl6qLbiEA_U

Here are our academic papers validating the technology:
Wiltschko et al., 2015 - https://www.cell.com/neuron/fulltext/S0896-6273(15)01037-5
Markowitz et al., 2018 - https://www.cell.com/cell/pdf/S0092-8674(18)30512-9.pdf
GP says, and I concur, that the scientific method would not to be just say "this must be impossible, let's ignore it", but try to disprove the study (maybe by trying and failing to replicate the study, or designing better studies).
This is definitely true, at least for Eastern Germany where I grew up. The best you could get as a 'citizen' was a typewriter. Any sort of printing or copying machine was off-limits (edit: at least until the mid-80's, you could definitely buy a 9-needle-printer, but those things were scarce and expensive, I remember that I sent cassette tapes with source code via snail-mail halfway through the country to a guy who had access to a printer, and a few weeks later I got the printed listings sent back) :D

East Germany put a lot of effort into tech-education though. The "glorious leadership" realized that they were quickly falling behind in high-technology during the 70's, and they actually tried to fix this.

Most of the 8-bit computers that Eastern Germany started to manufacture in '84 were former 'grass-roots' designs done by hardware engineers as side projects.

When the government desperately needed cheap hardware for education, those side projects got green-lit and were developed into official projects. This is where reality kicked in again unfortunately, the limited resources of the "real-socialist economy" didn't allow for the mass production necessary to fulfill private demand, so everything that was built went to schools and universities (at least!), but also military academies.
At Sonato we are building the next generation software platform for the hospitality industry. We're looking for engineers to help solve real world challenges in hotel, restaurant and fitness businesses to name a few.

We are an equal opportunity employer. We are a welcoming place for everyone, and we do our best to make sure all people feel supported and connected at work.

https://www.sonato.com/jobs/
Note: we can and do provide visas for fulltime work.
You can do an executive MBA and also a lot of companies will pay back your tuition when they hire you. Or you can get a company to pay for it outright.
When does SQL statements get executed when we run sp_execute_external_script?
>You have to look at really successful indie games, such as Terraria, Factorio, Mini Metro, Stardew Valley, Darkest Dungeon, Papers Please.. and there are many more. If you look at these games do you really think there is an alternative reality where they would not sell many copies? I don't.

One thing about all of those is that they pass a smell test. I don't need to play it to be interested, if I just see an ad or see someone playing or hear someone talking about it then I'm interested. This game did not have that, all I've seen is a genre and some bad graphics. The gameplay itself could be great but it hasn't gotten past the smell test.
AppZen is looking for a Java Engineers to extend our existing applications and to create new applications. In this role, you will develop technology solutions that are scalable, relevant, and critical to our company’s success. We believe in building the right product, we believe in using best practices, we believe in everybody's input. You will help drive us to a continuously delivered microservice environment.

https://jobs.lever.co/appzen/9229bc52-9223-4bf4-8f6b-75547fb...
Even just having investments in Cannabis stocks can cause a lifetime ban
https://www.ctvnews.ca/canada/why-investing-in-pot-could-pos...

>Even though Znaimer didn’t admit to personally using pot,
he was given a lifetime ban anyway because of his
investments in U.S. marijuana companies, he said.

>In one case, Saunders said an Edmonton man received a
lifetime ban from entering the U.S. simply because he was a
part-owner in a Colorado building that leases space to a
pot dispensary.

So what is stopping them from denying entry due to search history?
very cool. THEY LIVE inspiration :)
You too can use the Feynman Algorithm
This is terrifying. Full stop.
I have found that immutability is actually simpler to understand (and, potentially related, results in fewer bugs per LOC written), it's just that everyone's (including mine!) first language is usually procedural/mutable so that seems to be what is "easy"
In this post we look at when SQL statements are executed when executing external scripts?
I thought this was going to be some sort of analog computer made out of concrete.
Twitch | Engineering Manager | Video Delivery Infrastructure | San Francisco| Full-time | VISA

Twitch is the world’s leading video platform and community for gamers, with more than 100 million visitors per month. We connect gamers from around the world by allowing them to broadcast, watch, and chat with each other.

Twitch’s live and on-demand video platform forms the backbone of a distribution network for video game broadcasters including pro players, tournaments, leagues, developers and gaming media organizations. Twitch is leading a revolution in gaming culture, turning gameplay into an immersive video experience. Learn more at http://twitch.tv

We’re looking for Engineering Manager to join the Video Delivery/Distribution team and lead a group of talented and motivated engineers. We are on the cutting edge of live video delivery and have the best low latency solution in the market today at our scale.

Feel free to reach out to me at jyo+hn@twitch.tv for more details. Here is the job posting: https://jobs.lever.co/twitch/645c2459-6b07-41c0-a814-4538916...
To make the analogy complete, it needs to include a global mail network that accepts these magic boxes and transports them almost instantaneously at almost no charge, so that you could trivially avoid any requirement to show customs what's inside by mailing your stuff to yourself after you get through.
TalkJS (https://talkjs.com) | Eindhoven (the Netherlands) | REMOTE (Europe/Africa only)

TalkJS is the chat platform for platforms. We help online marketplaces and communities build great user-to-user communication. Working at TalkJS is fun because you get to make software that is used by other software engineers and that significantly impacts the experience of the users of our customers. Currently we're looking for a:

JUNIOR PROGRAMMER WHO CAN WRITE

We want to make it even easier for customers to build TalkJS-based chat UIs into their sites and we need your help. Therefore, we're looking for someone who's currently better at writing than at coding and is looking to reverse that (by getting better at coding, not worse at writing :D).

We can give you an opportunity to deeply learn tens of technologies in a brief time, all while producing useful community content (tutorials, code examples, SDKs, etc) for our customers and would-be customers.

ABOUT YOU

Our team is small and highly proactive, and we expect the same from you. If you need to be told what to do all the time, don't apply. If you want to be the smartest person in a (chat) room full of interns, don't apply. If you want to move fast with an experienced team, get in touch.

Apply by sending an email to hey@talkjs.com. (no recruiters or agencies please)
The issue is expressly the commingling of items. There's no way to determine which seller shipped in the counterfeit items. Requiring a vendor sticker would do that.
It isn't a matter of whether it's "secure" or not. The problem is that their security model is based around JavaScript code being pushed to your browser where all the "cryptography" will happen. Yes, maybe your e-mails are actually encrypted. But let's think that for example their servers get compromised, by exploiting whatever vulnerability they have, or even one of their employees gets phished. The attacker will be able to serve you a malicious JavaScript file and get your passphrase and decrypt all your e-mails.

This risk is real even in the hypothetical world were everyone uses ProtonMail, but in the real world you have a bigger risk: most people don't use ProtonMail and the risk of your e-mail being included/forwarded whatever to a "plaintext" service is really high.

I would recommend to avoid ProtonMail and other e-mail services that claim to be secure, and stick to end-to-end solutions like Signal/Wire/WhatsApp.
Memrise | Software Engineers, Data Engineers | London UK | Full-Time, Onsite, Visa sponsorship and relocation available | https://www.memrise.com
Memrise gives people learning superpowers!

We've got:

* An impactful mission - Memrise helps users achieve confident, real-world language skills & connect with new cultures.

* Exciting technical challenges for you to work on. We build for scalability & high availability; use machine learning powering real-world, user facing features; have big data to process and feed into our adaptive learning algorithms; and smooth, refined user interfaces to build that our users will adore.

* Funding - we just closed our Series B at $15.5M!

* A large user base - we now have about 40M users!

* An awesome team - https://www.youtube.com/watch?v=wORv8J1n0y8

We're looking for:

* Mid-level and Senior Backend Software Engineers. We use Python 3.6 / Django / MySQL / Redis / Celery running on Kubernetes / AWS.

* Senior Android Engineer. We're App of the Year 2017 on the Google Play Store.

* iOS Software Engineer. We use Obj-C/Swift & our app is regularly featured - https://itunes.apple.com/gb/app/memrise-learn-languages/id63.... .. and you might have spotted us at WWDC this year using CoreML - https://twitter.com/memrise/status/1003731119639007232

* Senior Data Engineer. We use Redshift, Segment, Looker, Airflow and Apache Spark, all on AWS.

Apply at https://www.memrise.com/jobs/
Python has a lot of weird/surprising corner cases. In fact I'd argue that Ruby, a similarly capable language, has a lot fewer warts, which is why it consistently surprises me that Python is "doing better than" Ruby.

https://wiki.python.org/moin/PythonWarts
The unfortunate thing about negotiation books is that people begin to see all forms of human interaction as a negotiation. Negotiating when buying a car, sure go for it. But if you've scratched someone else's car and they're asking you to pay for it. Maybe not the best time to whip out those negotiating skills.
bypass iOS 12 lock screen
Fair.com | Full-time | ONSITE | Santa Monica, CA | https://www.fair.com/careers

Fair is a FinTech company that provides a new way to shop, get approved and pay for your next car—all on your phone. It gives customers the freedom to drive the car they want for as long as they want, and the flexibility to turn it in at any time. Fair is headquartered in Santa Monica, California.

We're hiring for multiple roles in engineering:

* Senior Software Engineer

* Mobile Engineer - iOS & Android

* Senior Data Scientist

* Data Engineer

* Platform Engineer

Short list of things in our stack: Python, Ruby, Golang, Postgres, Elasticsearch, Redshift, AWS, Kubernetes

Contact: belindas@fair.com
Just to add another piece of feedback - I'm someone who has written production Clojure + Datomic apps and still don't understand what this product actually does. Not withstanding the direct link to the demo, your actual homepage (http://www.hyperfiddle.net/ - had to work too hard to find it) doesn't say much about what this does.

The first paragraph of actual text on the page says "Isn't a tool this powerful too dangerous for production?" - you're trying to debate a problem I haven't even mentally flagged because I have no idea what it does. The demo vid is way too fast (and long - the worst combination) for me to get an understanding. I'm generally in-favor of having a demo video as the first thing on your site but only if it's max 20 seconds long and gives me a very clear picture of what it does.