skysight-inc/HackerNews huggingface dataset:
Bacterial resistance in animals is a topic on its own (which I believe will bite us back in not-so-far future), and I don't believe for a second that the chemicals cattle is fed don't end up in the final meat on the plate in substantial concentration. There is no magical process that somehow removes them from deep tissue.

Now somebody can claim consuming animal growth hormones or strong antibiotics regularly can do you no harm, but I wouldn't believe this person. I prefer to not be part of long running experiments involving few billions of involuntary participants.

Quality of the meat, at least taste-wise, is probably unaffected by these. Much higher effect has caging/free range/wild, shocks and stress animal has to go through life, particularly at its very violent end.
Selegiline
FWIK 5G is going to use mostly the spectrum bands freed by the move from analog to digital TV, or at least that's what I've read briefly on the argument, so there's something that I'm missing that makes phones more dangerous than TVs?

Well other than having more cell towers than TV repeaters...
What does "socially accepted" mean? Both nicotine and alcohol have centuries-old integration into social customs...

More likely there are two factors at play:

1. The alcohol industry is a massive source of tax revenues (unlike guns or tobacco).

2. Educated voters across the spectrum enjoy alcohol but have largely left smoking behind ("people that matter").

Everything about regulating vices falls down when it comes to alcohol. Every indictment of guns or tobacco (dangerous, unhealthy, societal harm) is amplified for alcohol...yet it gets a pass while other vices are condemned.
They are legally people under the broken legal system of America. I will treat their crimes, their lack of morality, their low ethics, and their sociopathy the same as a human as long as they are "people".
why are you unconvinced about fasting? have you tried researching and reading the scientific articles about fasting and the other topics.

If you're thinking in terms of "holy grail," you may be subjecting yourself to an "all or nothing" fallacy.

Generally, we're discovering how to lead our bodies through the healthy operating conditions which kept our ancestors alive as we navigate a modern world of high-tech capabilities, treatments and availability crossed with widespread lack of discipline and healthy habits.
Very true, Ben Sasse recently had a good statement on this topic at the Kavanaugh hearings.
> In theory, competition among PBMs for the business of payers like the jail mentioned in the article would drive lower costs for payers.

I noticed that all of the spread graphs in the article were going down and to the right. Even though the spread was increasing, it seemed that prices were going down over time.
What do you consider the strongest sources for those claims, especially the second hand smoke claim?
We'll get very fast single program environment which is not transferable to another slightly different computer.
Maybe, but I think if it happens at all, it's going to use some other form of neuroimaging. MRI needs a lot of power, a shielded room, strong magnetic fields (which are both annoying and dangerous). Many of these are physical constraints rather than just...where the market happens to be.
oh metalevel eDSL, I was expecting standalone sql parsing :)
Last I checked, nicotine isn't carcinogenic. It's the tobacco that kills you. Or, at least, there isn't enough research yet to say that nicotine alone is harmful enough.

So I may be playing devil's advocate here, but isn't this a net improvement over the last few decades? Kids getting hooked on something that's significantly less deadly? It's not ideal, sure, but it's better than a slew of cancer epidemics.

What is the FDA trying to achieve?
we collect dongles as employee leaves.
I, too, am a former smoker and I have questions. Mostly how a device that delivers the addictive substance helps you quit.

Were you taking a "step-down" strategy like with the nicotine gum? Since the gum is carefully regulated and the "juice" isn't, how can you be sure your step-down is actually doing anything? And since the gum is metered out in measured doses, what's to prevent you from just grabbing full-strength juice and falling off the wagon? (Compare with smoking, which means you ostensibly have to go and buy a pack of smokes and a lighter, assuming you followed step 1 in the gum and got rid of your cigarettes and lighter)
This app looks a bit like what I need, but not quite.

I practice martial arts, and would like to improve my overall fitness. Strength is obviously part of that training, but so are flexibility, speed, and reaction times.

I have yet to find a training plan that accounts for all these factors. Even worse, some of them tend to negatively correlate with each other: when done wrong, for instance, strength can negatively impact flexibility.

I thought this would be an easy problem to solve. But so far I've had no luck. I guess there is more to biology than just solving an optimization problem.
Sleep, and a mix of cardio and strength training would most closely replicate how our bodies evolved. Pre-civilization, humans would have needed both strength and endurance to make shelters and hunt. Both running, and lifting/moving heavy things would have been common.
Home loan guarantees had nothing to do with the financial crisis. The loans that failed were overwhelmingly issued by private institutions backed by capital from private institutions, and carried no government guarantees at all.

Drug costs also have little to with government subsidies since they are set by negotiation between private drug companies and private insurers. Medicare and Medicaid must pay those (privately set) prices.
No, we should precisely look to let kids "down easy" from their errors, rather than ban activities that can lead to those errors, for the very same ends that you're advocating. When too many possible mistakes have big irreversible penalties, everyone becomes much more risk averse, and the society becomes boring and rigid. See: helicopter parenting.
Outsourcing by Plamen Nedyalkov, Founder and CEO of Zoom
Playing around with a tool is still using it. Who cares if it's ridiculous? Getting anyone to be engaged with something new is way easier if they're passionate about it. If a kid wants to edit a video about farts, they're going to learn what it takes to make that fart video, and I applaud them.

Also, the marquee tag is mission critical.
I disagree. Quitting at any age, even after 40 years of smoking, is still very beneficial to your health. I don’t see any of your “statistics” linked.
It's not a moral panic, in the sense that people don't like kids smoking. It's a public health issue. Juul is bad for kids' health, it causes similar problems as cigarettes, even though it's relatively safe. [1] You can't sell cigarette replacements in 2018, half the price, in a nice package, deceiving kids who have absolutely no idea what the heck they're doing, and expect to profit legally and morally from this.

[1]: https://news.psu.edu/story/527326/2018/07/03/impact/medical-...
it does, loosely. However, box mods are still quite rare, so it's not super clear that the narrative of "people stopped smoking and started vaping" really holds -- or held until Juul took over, which is quite recent.

It's fairer to say that an age cohort basically just stopped consuming nicotine at all, and that a new, younger generation has picked up again but switched delivery methods.
The examine.com article discusses this - 0.8g is also the RDA in the US. The RDA is considered a bare minimum:

This is considered to be the minimal amount of protein a healthy adult must consume daily to prevent muscle wasting when total caloric intake is sufficient.

According to recent studies, however, the RDA for protein may not be sufficient for healthy young men, older men, or older women. These studies point to 1.2 g/kg as the minimum intake before the body starts downregulating important non-essential processes, from immune function to muscle protein synthesis. Even a reanalysis of the data used to establish the RDA suggests the minimum intake should be at least 1.0 g/kg.

They cite a study there where they shut subjects in a metabolic ward for 8 weeks and fed them a 40% caloric surplus. Those subjects eating near the RDA for protein lost muscle mass, i.e. it's not even sufficient to maintain lean weight when overeating.
The human trust problem isn't the weakest link, the application is. Way more applications get hacked than humans.
It's a good start, but you're supposed to do it more than once iirc.
Is this a trick question? The answer would be a clear, strong "yes". Inducing a permanent, expensive addiction in minors versus giving grownups a moderately shitty job?
Vue-internationalization-service to export and import SFC locales
Can you point out any specific “dangers” of employees having LinkedIn accounts?

How much $$ over market value would you offer to compensate an employee for not using it?
I get that torque for EVs is ~independent of rpm. But still, there's just one set of gearing, right? So the effective torque at the wheels is also ~independent of rpm.

And yes, torque at the wheels is likely much greater for Teslas than for my Civic VTEC in third gear. But I wonder about second gear. I mean, the car has wide low-profile tires, and I can spin them on dry pavement in second, from a standing start. And it takes some skill to avoid doing that when starting in first.
This is shocking.

So Microsoft is using their smart screen tools to recognise the exes and then warn you.
The Royal College of Physicians strongly disagrees with you. This is the same group that sounded the alarm on cigarettes in 1962 with their groundbreaking report "Smoking and health" [1]. Their 2016 report, "Nicotine without smoke: Tobacco harm reduction" [2] stands in staunch disagreement with your statement.

[1] https://www.rcplondon.ac.uk/projects/outputs/smoking-and-hea...

[2] https://www.rcplondon.ac.uk/projects/outputs/nicotine-withou...
Wrong cert. is installed, use http instead: http://alertfor.com
It's fraud, subject to jail just like other types of fraud.
> The FDA is in an interesting regulatory bind here, too -- I think nicotine is unique in their regulatory scope in that the FDA is concerned with efficacy and safety and tobacco products are known to be unsafe and ineffective therapeutic agents.

Thr tobacco industry tried this approach, claiming tobacco is an "agricultural product". Congress fixed that by passing a law specifically authorizing the FDA to regulate tobacco, which includes smokeless nicotine products.
It really doesn't seem particularly deep in the red. 284 billion ¥ annual deficit for 32 million people, that would be covered entirely by raising everyone's premiums 750¥ (less than $7) per month.
Not arguing your main point at all, but I wanted to correct your last statement. While not considered safe, cigarettes have proven to be remarkably protective against the development of Parkinson's disease in a slew of studies spanning decades of research. This is relatively little-known outside of the field. I did my PhD in Parkinson's drug discovery, and it was one of those findings that is frustrating due to the lack of other effective therapies for PD prevention and the obvious deleterious effects of smoking on heart disease, lung cancer, etc. Here's a relatively recent review paper on the topic: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5494127/.

Relevant excerpt:
"Population-based studies have shown that smoking was associated with approximately 40–50% reduced risk of developing PD. [10, 11] This inverse relationship between smoking and PD was dose-dependent: age-adjusted relative risks (RRs) of PD were 0.8, 0.6, 0.5, and 0.4, for 1-9, 10-24, 25-44, and 45+ pack-years, relative to never-smokers, as shown in a large prospective cohort study [9]. There is also a temporal relationship between cigarette smoking and PD risk [9, 17]. Individuals with more years of smoking, older age at quitting smoking, and fewer years since quitting smoking had lower PD risk. Researchers prospectively observed a significantly lower risk of PD for smoking as early as 15 to 24 years before symptom onset, but not for smoking 25+ years before onset (n = 143,325) [17]."
They want your money all the time now not just when they actually make a better product.
> It’s not impossible to write, but just extremely hard for anything that is not trivial.

I think @laumars meant impossible in practice, not impossible in the strict mathematical sense. We can speculate that in theory it’s possible to write bug free programs that are large and complex, but nobody has ever done it. And not for flaky hardware or compiler reasons, all large software has many software defects, bugs in the design. It is not currently possible in practice to write a program like SQLite that is bug free, and no analysis of halting problem or number of input bits will tell us whether it could actually happen. Nobody even uses metrics like that for software stability because they don’t tell us anything practical.
But this is somewhat an admission of using it as medication, which is far from what Juul is being marketed as. It should be next to the nicotine patches at the pharmacy. Can you even buy nicotine patches in bulk? Substances that can be abused for something other than their primary use as medication are heavily regulated by the FDA (think meth ingredients).
Are you still stronglifting after 2 years? How has your progression been for the last year or so of that? As I understand it it's a fairly novice focused program with aggressive weight increases, so I was wondering how you modified it to continue running it after the first 3-6 months of easy gains went away.
Remember when we made good games that people played for the sheer enjoyment of it and didn't need marketing witchcraft to hand-hold lazy designers?
Okay. let's talk about Box.

Box<T> is always a single usize if T is Sized, and two usizes if T is not. T is not sized when it's a trait. If T is Sized, then Box<T> puts the T on the heap, and the Box itself is a pointer to it.

Box<Fn()> is a "trait object" the double pointer. It looks like this:

pub struct TraitObject {
pub data: *mut (),
pub vtable: *mut (),
}

The first pointer is a pointer to the data, and the second pointer is a pointer to a vtable. So in the Box<Fn()> case, data is the captures, and the vtable is the code.

So when you write code like this:

// in a function body somewhere
let x = 5;
let f = Box::new(|| x);

Rust generates code that looks roughly like this:

// at item level
struct Env<'a> {
x: &'a i32,
}

// an impl of Fn for Env, i'm not writing that out

// in a function body somewhere
let x = 5;
let env = Env { x: &x };
let memory = GlobalAlloc::alloc(..);

// copy env into memory, i'm not writing that out

let f = TraitObject {
data: memory,
vtable: pointer_to_vtable_im_not_writing_out,
}

make sense? The Env is on the heap.

Before I move on, It's worth noting that, in the case of a closure which has no captures:

let f = Box::new(|| 5);

you get:

// at item level
struct Env;

// an impl of Fn for Env, i'm not writing that out

// in a function body somewhere
let x = 5;
let env = Env;
let memory = GlobalAlloc::alloc(..);

// copy env into memory, i'm not writing that out

let f = TraitObject {
data: memory,
vtable: pointer_to_vtable_im_not_writing_out,
}

since Env is a unit struct, it has zero size, and so gets optimized out at compile time, which also ends up removing all of the data stuff, which means it's back to a regular function pointer (fn instead of Fn).

Anyway.

So, if we were to do an SSO-like optimization here, we only have a single usize, the data pointer, to work with. We still need the function pointer, so we can't re-purpose it.

In theory, that would mean that an environment that has a total size of less than usize could be stored inline. It's not clear to me how often this is true, and if it would be worth it. But none of these internal representations are stable, so it's possible for Box<Fn()> at least.

Compare this to std::string. Different compilers implement it differently, but let's look at gcc:

https://github.com/gcc-mirror/gcc/blob/master/libstdc%2B%2B-...

https://github.com/gcc-mirror/gcc/blob/master/libstdc%2B%2B-...

You've got a pointer to the data, the size, and a union of the buffer vs the capacity. In the end, on a 64 bit system, this is 32 total bytes of space! Box<Fn()> by contrast, is 16 bytes total, and we can only use 8 bytes of that. Additionally, strings often do have individual byte data, but closures, given that they capture by default, have a size of at least 8. maybe a move closure that has a bunch of small numbers in it might make a good fit for some sort of SSO-style optimization here, but environments tend to be bigger and space is smaller than strings.

Does that all make sense?
The point was that if you trade "make it easier to quit" for "more new addicts from candy nicotine products", you're making a bad trade. You really want me to cite the numbers for how many smokers quit? It's depressingly low -- like 30% over a lifetime or something like that.
A hackintosh is quite different from running macOS in a VM. And even if you wait “a few days” you are part of such a small group of users that you know very little about how you might be affected.
I was curious, and did a google scholar search on the Finland folks. Didn't see anything to back up your claim. Just people who have expertise in related fields. Care to elaborate?
Spectrum fallacy. There is no "scale of morality," which goes from 0 to 10. Each of these can be viewed as wrong from different perspectives. Also, "exploit labor," is a leading term - there is labor exploitation going on, but also free association, while at the same time there are companies that engage in almost outright slavery. It's all over the place and you can't loop them together. If you give a 6 year old poison candy, it's clearly indefensible. If it's a 20 year old, "kid" well, most people will think that's his or her choice.
I think I look OK for 47. I've been lifting 4 times a week since I turned 40, mostly on 5/3/1 but lately on some bespoke programming. It's all based around the 4 big lifts, and after doing some amateur strongman competitions I occasionally add an events day as well.
Probably on piles of money.
Low out-of-pocket is an advantage in and of itself.

The total cost calculations that show the US system to be twice do include taxes spent on health care, naturally.
It'd be fairly difficult if the detection was registering a web browser with the operating system...
Vaping is not the same as smoking.
Why Seclusion Is the Enemy of Creativity
As many probably realize, the fact that "online videos" == Youtube for many members of the general public means that it is by far the number one source for both posting and watching videos online in a self-reinforcing loop. I think that it cannot be overstated how much the existence of platforms like that (e.g. video sharing websites, 2D art websites, music boards) drive non-professional creators to create, given the fact that for the first time, they can actually get an audience. So it is not so much that Youtube and similar platforms are necessary for content creation (which is a ridiculous claim that no one made), but that the absence of such platforms seems likely to result in the previous system where media was very rarely shared by the non-professionals.

If you are arguing that massive content consolidation platforms such as Youtube do not have a highly significant impact on content creators as a group though, then I do not know what to say to that.
>And LSD, without which there would be no psychiatric drugs.

[citation needed]
There's a lot more kids out there than current smokers.
Utter rubbish. The research has just begun and it will take a while to conduct epidemiology studies (basically we have to wait for people to die from e-cigs), but the prognosis is already poor. Here's one study from this year:

http://www.pnas.org/content/early/2018/01/25/1718185115
I just read a very interesting history book (Before European Hegemony, by Janet Abu-Lughod (sp?)) that said that China was one of the first countries to have paper currency and that as early as like 1100 if I remember correctly, foreign merchants would try to go to the market with gold coins and they would be turned away and told to go trade in their gold for currency.
I agree with you to an extent but the issue isn't so much who's to blame for unexpected behaviour but rather who's responsible for fixing it. You could make all kinds of reasoned arguments about who's to blame if a compiler optimisation or even outright compiler bug caused good code to behave badly under certain conditions but ultimately the end users don't care as they would still expect the application developers to fix the build scripts and/or project code regardless.

To use the ships navigation system example, if you have some kind of "auto-pilot" system that would steer a ship into central London when a bad destination was set, then you'd quickly demand the authors of the auto-pilot to write exceptions for bad destinations.

That's the ugly side of development; all too often us developers are having to write code to handle ugly systems. It's not fun but it's usually necessary.
Watching flashing lights to help with trauma – does EMDR therapy really work?
Sounds like a lot of nice fines or jail terms to be handed out to whoever sold/gave them to the kids. What kind of investigation is being conducted to find out who's responsible?
I was just in China a couple months ago, and you can definitely use cash everywhere. But it does help to be with someone who can pay using APP (ay pee pee, that's what they refer to it as)
"git checkout -" is even better if you alias "checkout" to "co" since it just becomes "git co -".

Stash has to be my favorite (especially with "-u" AKA "include untracked").

I'm generally very comfortable doing even advanced stuff in git, but still get paranoid about some things. Especially when I'm trying to troubleshoot something for someone else.

Being able to stash away current changes in a place that is separate from any particular branch is invaluable.

I often show stash to people that make a habit of copying their entire project directory before doing something they aren't sure about (backups aren't inherently a bad idea, but that's why you push early and often).
It seems like it might not just be a replacement effect, though. Adding those numbers together, and pretending that 2016 == 2017, you get an increase from 17.3% of kids using either in 2011, to 19.3% in 2016/2017.

Perhaps you can make an argument that, lacking tar and being (purportedly?) less addictive, e-cigs are enough less bad that a net increase in the number of kids consuming nicotine is an acceptable price for halving the number of kids who are smoking cigarettes. That's a more arguable argument, though.
30ms really sounded a bit much for me, if you take network-locality as a precondition (i.e. adserver on same physical sub-1ms-network than webserver).

But yeah, it should be loaded async. Been a while since I worked with ad stuff, but I thought 10ms-20ms sounded more likely.
I'm not advocating Juul use as a strategy for quitting. I'm merely sharing my own experience, which was that Juul was the only thing that allowed me to quit (after 10 years of many attempts using most available options). Why did it work? I'm not sure. Perhaps it created just the right amount of elasticity in my addiction.
How to Deploy a Production-Ready MySQL or MariaDB Galera Cluster
> Kids getting hooked on something that's significantly less deadly? It's not ideal, sure, but it's better than a slew of cancer epidemics.

The whole point is that these are kids who wouldn't be using nicotine products at all. Smoking rates have declined in the US over the last 40 years, and yet there's been an uptick in youth nicotine usage since the introduction of e-cigarettes.

So when talking about youth usage, no, this is clearly not an improvement, by any measure.
I used to have a boss that effectively wouldn’t hire people if they didn’t have a LinkedIn.