skysight-inc/HackerNews huggingface dataset:
They are probably only applying the 700 genes as single factor interactions. I doubt all genes affect height. It only takes about 33 gene variants to have more genetic possibilities than there are people on earth. If they interact non-linearly, they are almost impossible to find by genetic surveys.

A fundamental problem with genetic analysis is that gene variants are categorical variables that often have non-linear effects, but predictive power goes down drastically as soon as you start looking for multi-factor effects. You have to narrow down the multi-factor search space, possibly by narrowing it down to genes that have a linear effect, but that could still be too large and you could easily miss genes that on average have no effect.

I wrote a critique of a paper using this method. I proposed studying the distribution of variant data's residual distance from a single-factor linear fit. Consider a variant that has a positive effect on height when combined with another variant, but a negative effect otherwise. The single-factor linear fit will assign it 0 effect, but residuals involving the variant will be unusually large, positive when the second variant is present and negative when it is not. My critique found several variants fitting this description (after a bonferroni correction), but i didnt have the compute power or time to rerun the 2nd order interactions with my findings.

But hey, I got a B on that paper, so maybe it's a terrible idea.
Strangers with Similar Names Meet Through Emails Sent to the Wrong Address
Photos here:

http://blogs.discovermagazine.com/d-brief/2015/01/30/scienti...

Not at all like modern tattoos. I wasn't expecting anchors and skulls, but these are very simple and don't appear to have any rounded edges.
We get both the Jewish and Christian Sabbaths off each week. We have more leisure and chance to reflect then ever before. It's our fault if we burn it up playing video games, watching tv, or working.

I've found that since I've started in software engineering I have much more trouble calming my mind down and thinking deeply. I'm trying getting up early in the morning, getting some exercise, food, and reading the Bible, which tends to get me into a more contemplative state. I just started, it's brightened my outlook and made me feel like I have more time in the day, though I can't tell if my work is benefiting yet.
Animated arpeggios on the fretboard view please!
Well, the 2012 model was very nice. Also OSX of the era was bit better perceived than current ones, I think it was in some ways around the peak of OSX.
I know exactly what you mean! It is astonishing that Holmes and her love toy could perpetrate such fraud. That fact that they could fool the caliber of people that they did fool is mind boggling. The only thought in my head once I finished the book was that I hope these two spend a good part of the rest of their lives in prison.
Not quite endless, I found an 3 edges of the space. Couldn't move beyond.
The key points to know about the significance of Taiwan:

Geography is still very significant. The potential for others to base aircraft and ships on Taiwan keeps China contained behind the South China Sea.

Taiwan is a hard target for amphibious invasion, and amphibious invasions are hard to begin with. The seas around Taiwan are quite rough, and there are only two potential beaches for such a landing. The time frame friendly to such an operation is also quite limited.

Basically, if China keeps on ramping up its blue water naval capabilities, some kind of confrontation is inevitable between the USA and China over the South China Sea and the US position as distant ally/hegemon to Korea, Japan, and other east Asian countries.

China's Geographic Challenge: https://www.youtube.com/watch?v=H8uWoBtCkg8
Assuming we're still going with 1 minute a day saved which was an intentionally low estimate we're still talking about 12 years worth of time saved over the course of a year. Those minutes add up.
and you don't have to bother pairing them...
Yeah, seems to be A Deepness in the Sky:

https://en.wikipedia.org/wiki/A_Deepness_in_the_Sky#Interste...

Recently read A Fire Upon the Deep personally, and don't recall much/any mention of it there. :)
rc from plan 9 is simple but quite powerful and has very clean syntax. It also does away with the cruft in bourn.
http://www.scs.stanford.edu/nyu/04fa/sched/readings/rc.pdf

There is a port of a few very useful plan 9 tools, including rc and the Acme editor, in https://9fans.github.io/plan9port/

https://en.wikipedia.org/wiki/Plan_9_from_User_Space
A math degree is worth it. Learn graduate level statistics and machine learning. Then apply it to something.
You forgot the prison camps -- https://foreignpolicy.com/2018/08/22/chinas-mass-internment-...

Around 1 million Uighurs have disappeared without trial.

So much for "never again" after WWII... as long as our iPhone's are cheap, people seem happy to look the other way.
I disagree strongly. There are cryptographically secure algorithms for voting, that allow you to ensure that your vote has been counted in the final tally (and counted correctly), by returning to you a token that will be incorporated into the final count. You can also securely determine the precise number of votes cast. All of this without sacrificing anonymity.

https://en.wikipedia.org/wiki/End-to-end_auditable_voting_sy...

For more. We absolutely should be using these systems and the fact that we have allowed electronic voting machines to be used that do not conform to these protocols is an absolute travesty of democracy, considering how easy it would be.
You know it's a pun on conch shell, right? ;-)
When executed from DOS by means of INT 19h and NT MBR it complains that there is not enough free conventional memory.

This shows that somebody though that it is good idea to write ntldr as valid DOS program, that actually cares about the state of DOS on which it runs. (ntldr actually is concetanition of 16b MZ EXE and two COFF images, ie. something that DOS is perfectly willing to load and execute)
Just like the OG Joda, I'm assuming it doesn't support nanosecond time resolution?
I’d say “start killing people” is a great solution when other people are trying to kill you (e.g. WW2, Korean War).
Religion is so much closer smoking than work.
> They have way more data than either of us do, and the market has spoken: there is not enough demand for small phones to justify a separate SKU.

Let's not pretend this is some natural result of "the market". The UX of most iOS apps, including Apple's, has been steadily getting bloated with bigger buttons, bigger labels, more padding in text fields, and reams of whitespace. This is personally annoying, but manageable on the bigger, newer phones. On iPhone SE it means that many apps can be maddening to use - with only a little bit of content visible on screen in some situations.

iOS 7 on the iPhone 5 form factor was great. iOS 12, not so much. Apple clearly sees no future for the smaller phones and their UI designers consider them an afterthought. It's little wonder that only diehards are willing to put up with this kind of UX compromise.
The 'Dune' series by F.Herbert, and continuation by his son. God emperor of dune is definitely worth reading up to.
You have roughly 3 main toppings per pizza before it becomes a cluster-fuck, maybe 50 ingredients if you're stocked. There are 125k combinations, half of which obviously won't sell, 49% of which might sell as a novelty, with the remaining 1% being the combinations people mostly know about.

If the menu has 20 new combinations per day, I'm having a hard time seeing why an AI would be better able to derive a new list per day than a motivated high-school cooking class is.

If a mechanical robot had some precision, I'd be more interested if an AI was trained to place the ingredients in optimal locations (r, theta) on the pizza, so as to maximize enjoyment and minimize cost.
Ironically, the founder of partpic, the acqui-hire on which this technology is based used to work for Mcmaster-Carr and started partpic as a result of customers' frustrations with McMaster's search functions. Perhaps they're aiming this product at more casual, less exacting retail customers who'll settle for only an approximate match in exchange for the convenience of snapping a quick pic. It's a shame though if they can cater to all types of customers by improving their search function.
"Chasing New Horizons: Inside the First Epic Mission to Pluto" by Alan Stern and David Grinspoon

Fascinating tale of the history and triumph of one of the most amazing scientific marvels of the age of robotic space exploration. Nine years and 7.5 billion miles to arrive at a place that, up till then, was usually seen as a few pixels and a blurry image.
In a word - emotion. To be specific, fear which is largely responsible for survival is a huge contributor.

In general, Those who can manipulate others emotions by triggering them can manufacture certain outcomes. If you create a environment of fear humans can do a lot of things that otherwise outside the context of fear would be unspeakable.

Fear in the masses usually leads to confusion and/or convictions. Confusion is what allows bystanders to do nothing. Conviction is what allow doers to do.
Social+Capital now Kleiner Perkins....
> The majority of the left does not consider safe spaces to be part of equality.

Of course they do. Their central claim is that systemic inequality disenfranchises marginalized groups and safe spaces are needed as a counterbalance to oppression.

> Safe spaces are about segregation, not integration

This is your own political spin, the left definitely does not agree with that characterization.
I like to think you can find the good in almost any area. When I travel I make it a point to eat at local restaurants. No chains. I’ve had some really good food and met great people.

I haven’t been anywhere exceptionally dangerous since I was younger.
While buying something and having it auto-magically become better via over the air software updates sounds appealing, clearly there's a counter narrative here...

Anybody remember all the Nest Thermostat owners freezing in their homes during the winter? https://www.theregister.co.uk/2016/01/14/nest_foul_up/
It seems weird to argue this when your average driver has a much much higher risk of death than the pedestrian even in the worst case. It's not so much drivers offloading risk to someone else but recognizing that when human life is involved our estimation of risk is blown out of proportion.
Then you won't mind explaining why it's not an assertion of fact...
Oops, back up now!
It takes me an hour to get to work and an hour and half back. But, I live in California and only 11 miles from work. Moving out here from the southern US was mind-boggling when it came to the traffic.

I live in a damn nightmare now and am looking forward to the day I move out of this state in less than a year.
> China and Taiwan have a long standing agreement that they are both part of a single China

More info please, this isn't what I know of Taiwan.
Zipcar Fundraising Breakdown
> /e/ is not obviously pronounceable

On the contrary, it's a scientific notation for a specific pronunciation of the letter e.

/e/ represents in linguistics an unrounded closed-mid front vowel.

https://en.m.wikipedia.org/wiki/Close-mid_front_unrounded_vo...
Meditations by Marcus Aurelius

Mans Search for Meaning - Viktor Frankl.

I know you asked for 1 and I am giving 2 recommendations but nothing wrong with being generous with good things.
What I don't like is the way people are conflating work and travel. Sometimes people tell me they go down the beach or a nice park to code etc, I just couldn't think of anything worse.

One thing I love about traveling is when I set aside time to "focus on traveling", do I really want to be traveling through some beautiful place while staring at my devices and responding to email? Nope.

I have worked full-time remote, from a well setup home office. That was fine.
> I'm sure that's true. I haven't personally lived in a conservative area in America for any extended period of time.

Whether its true or not, my point is that the complaint is the same as the one you articulated in your original comment.

> You should be judged for how you treat and speak to people, not for your political opinions.

Nobody on either side believes this; the right judges the left as communists destroying America and the left judges the right as Nazis destroying America, that's the nature of politics.
XPrivacy is not about blocking, it's about faking.

PrivacyGuard in LineageOS is about blocking.
Even if the concept is secure, implementation of any electronic voting system will never be secure.

All voting is vulnerable to hacks, even paper and pen. The key is to make it as expense as possible to hack a vote. In-person paper voting is pretty much as expensive as it gets.

Never mind that the general public will never understand what you said or ever implement anything like it.
For new parts, get used to RockAuto.com. Most things I buy there arrive by ground the next day (to MA from a local warehouse) or 2 days. 5% discount codes available just for the 3 minutes of googling. They have "cheap crap" parts as well as quality parts, so be thoughtful about your choice. The good parts are good (OEM is often available) and very competitively priced, with excellent search, and good logistics.

For used parts, there are a couple of online junkyards, but I've found the best plan is to find your local pick-a-parts and figure out which ones will pull parts for you. Most will in my experience, though if you go pick it yourself, you're likely to get it for far cheaper. The one in the town I grew up in had a Friday promotion where anything you could carry 50 feet was $25 (in the late 80s, probably $50 now). You could pull a transmission and get it for $50. You could pull a car hood and pile a bunch of small parts onto it and take that all for one price. The pick-a-part in the NH town I moved to after college had a basic computer system and a network of other yards they worked with. Ebay is another good outlet for some of these yards (with the associated markup). I've replaced a few parts on my wife's CR-V with Ebay junkyard parts with good results.

Even though it's annoying to pay a $1500 repair bill on an old car, if that buys you another year of service for the car, it's still a great financial trade. I do almost all my own work (no bodywork, paint, or tires and limited exhaust work) and find the price of parts quite reasonable.
Excuse me? What is so uncivil about my comment? I would point out the flaws of my own country just as quickly as I would those of Thailand. The culture of Thailand is a burden to its people, as well as its economic and education situation. To brush aside my comment is to condemn the good people of Thailand because without broaching the elephant in the room, nothing will change. Please take your fake social justice elsewhere, especially far away from your moderation duties.
I wondered about this, too, after running into the edges. I thought they would have made it "infinitely" generating, like with a periodic boundary or some tessellated space.
I purchased this keyboard two years ago, and it was absolutely worth the wait.
My thoughts after 2 weeks of use:

- The lack of an escape key was initially a real pain point, but with agent it was easy to change the backtick key to escape
- The feel of the keys are incredible, but I am coming from a cheap dell keyboard so I don't have a solid basis for comparison
- Mapping mod + hjkl to the arrow keys has been incredibly efficient
- The mouse mode in the keyboard is unusable in its present state, but hopefully the extra modules solve this

Overall I'd give it a solid 9/10, presuming that you remap the keys to fit your individual workflow
The thing is, the war never officially ended.

Another way to look at it is if the Confederacy never surrendered to the union and instead retreated to Cuba and became the dominant political force on that island.
I’m not the one who downvoted you, but I don’t see how a woman’s body size has a significant impact on their pocket size. Are you saying men’s pockets are a lot different in size when the waist size is 44” than the ones on a 30” waist?
This can't even qualify as pseudo-science.
Sounds like Halium with a dose of Anbox.
OMG... that's exactly what the problem was. I turned that off and performance is 60fps on Firefox once again. Now I need to figure out how to I detect the conditions that I need to turn it on/off... it actually works fine on some Firefox Windows installations at least.

https://bugzilla.mozilla.org/show_bug.cgi?id=925025

Looks like Firefox does the blur in software whereas the other browsers do it in hardware, but apparently you can turn on gfx.webrender.all to make Firefox do it in hardware, not that it seems to work for me...

Edit: It's just easier to turn off blur in Firefox always. So I'm doing that. Turns out there is a clever way to detect Firefox from CSS. Thanks so much for the suggestion!
1. Battery was replaced 3 months ago
2. I run it in "low power mode" already, otherwise it's a brick.
3. Battery Health (Beta) reports:
- Maximum Capacity 100%
- Peak Performance Capability
Your battery is currently supporting normal peak performance

I can touch the screen and it acts as though nothing is happening...swipes, taps, etc... then seconds later it will run through all the things I've been trying to do all at once... pretty much unusable at this point.
By your standard criminals are also a minority group.
Perfect opportunity to create the next Frank Abagnale of our Time to dazzle our minds and fool us into thinking he is fit for a burgeoning career. Because after all, nobody looks past a necktie.

Well done NYPL!
However, the most Apple's system is close sourced, meaning if they want to do something, you're still defenseless. There are no Eden now, you need to protect yourself.

People's will towards privacy is still weak, they don't know what those company could do with that amount of data. Ignorant, that's why those company keep doing what they do.

It's just like running a restaurant, as long as people can't see disgusting thing in their food, then everything will be fine and dandy, no matter how unhygienic the kitchen was.

Sad.
They would however hurt the quarterly profit numbers. The SE costs less and the profit margin of ~38% on $800 is less than ~38% on $1000+

It’s just business

Apple will probably sell 70,000,000 in 90 days this quarter. I think they know how to sell a lot of phones
As far as I'm aware, none of those companies knowingly gave that information over to the NSA. In Google's example, the NSA had tapped their inter-datacenter fiber lines to steal the data. That's why all inter-datacenter traffic at Google is always encrypted now.
I disagree that google is unreliable at scale and also I’ve found with the enhanced phone model it’s much better for phone calls then anyone else...
One of the parts you are thinking of is Matthew 7:13-23 [1]. The interesting thing about that is that people who are trying to do the things that Christians do are the ones that are not accepted. So yes, you literally cannot do things good enough, those guys performing miracles weren't good enough.

The only way to do things good enough is to, for lack of a better term, seek after Jesus. And then he works in your life, and that's the only way to "do the will of the Father". There are specific verses for all that, but to keep it short (and encouraging), just look up a few verses to Matthew 7:7-8 [2] "Ask, and it will be given to you; seek, and you will find"

One of my favorite things about Christianity is that even in this time with all of our knowledge and access to everything it is so widely misunderstood, in almost all of its principles people have almost the opposite conclusion from what was intended. It's fun to explain it, if I can assume I understood it correctly ;)

[1] https://www.blueletterbible.org/esv/mat/7/13/s_936013
[2] https://www.blueletterbible.org/esv/mat/7/7/s_936013
>Frankly, I don't buy it.

I'm Jewish too, and was never religious.

The parent is not selling anything, simply describing a recurring experience in a lovely way. It's not an argument or a pitch. To each his or her own.
Show me a BLE device that has years (plural) of battery life.
Its not for you then. The project is about getting away from Google.
No...it's much more expensive to hack an E2E auditable cryptographic voting scheme. Infinitely expensive.

> Never mind that the general public will never understand what you said or ever implement anything like it.

They don't need to understand it. It just needs to be in place, so that we can audit votes properly.
Sources? I hear this way too often.
How about an option to overlay the pentatonic scales over other scales, similarly to the way you color the root notes but with a different color? You could use a similar idea to overlay root-third-fifth or other chords. I think this would be useful for those of us who are still trying to build muscle memory, but still present information in a way that minimizes "stuck thinking."
I've fired guns too, it's a nice adrenalin rush and I felt very powerful. Uncomfortably powerful. It's ok if you like these feelings, but your comments seem like thin justifications. You can get these feelings without rampant gun ownership.
Paper ballots and manual counting isn’t that expensive and it’s not where we should be looking to pinch pennies.
Some random, not organized thoughts on the issue:

On HN, you have two hours in which to edit your comment or even delete it if no one has replied to it. If you aren't sure you want it to remain on the permanent record, you can remove it at that time.

People who think they can erase what they said at will tend to behave poorly. People who think they can change handles with impunity and fool everyone tend to behave poorly. They think they can get away with it.

There are valuable things said in comments that people often want to look back up.

Having a record helps prevent he-said-she-said style of arguments. People tend to remember things differently from what actually happened. A written record can show who actually said what.

If you say it once and someone is stalking you, they will remember it or even keep a record of it. If there is no record of your remarks for you to reference, you may well forget that x, y and z is out there.
I thought Telegram supported user privacy? Please explain.
Cat pictures don't interfere with my ability to interact with the web page.

The 2MB+ of bloated, unoptimised JS that you ship with your page that I need to parse and render before I'm allowed to see the 20kb of actual content _does_ interfere with my ability to use the page.
Why Rigetti's New Quantum Hybrid Cloud Service Is a Big Deal
It depends on how the "One China Policy" is interpreted, and it is interpreted quite differently quite differently by different factions within Taiwan. See: https://news.ycombinator.com/item?id=17982858
I love reading all of these comments by my fellow SE lovers. We should setup a huge meetup in SF to protest.

https://www.reddit.com/r/iPhoneSE/
I created a Google Finance replacement – https://stockdaddy.io – in my spare time. This can track your investments and returns including dividends for stocks and ETFs (real-time) and mutual funds (EOD). It’s basically a pure portfolio tracker without much of the frills of a full finance site. It's meant to be a solid performance tracker and good full screen layout to glance at throughout the day.