skysight-inc/HackerNews huggingface dataset:
> Many of the pros, even ones who have played against (read: got crushed by) OpenAI Five, still think it's very far away for the bot to out draft a pro team with the full ranked game rules and hero pool.

Neither AI experts or DotA experts have the necessary background to predict how close anything is to any level of future performance. DotA players are probably the worst to ask, because the AI is already stronger than they are at a subset of the game and they have no insight into how quickly that subset could be generalised into other aspects.

OpenAI has a list of something like 7 restrictions. Nobody has any real idea of how quickly these restrictions can be lifted once the OpenAI team has an AI that has mastered the game with those restrictions.

Eg, 5 invulnerable couriers is obviously a huge restriction - but once OpenAI knows it gains a benefit by ordering items, how difficult is it to lift that restriction? Nobody knows. Might be easy, might be hard.
The DEA drug schedule is a hot mess.

https://www.dea.gov/drug-scheduling

There's no planet where Ritalin has a higher potential for abuse and addiction than Xanax. Not to mention all the lower-risk drugs that have been categorized schedule I for political reasons.

Under the current system rohypnol is schedule IV but has special date rape laws passed to make possession of it punishable like a schedule I drug as a workaround.
With anxiety, cannabis has pretty mixed effects, and we haven't been able to create reliable medications derived from cannabis that help. I've seen cannabis exacerbate as much anxiety as I have seen it help.
>70-90% price increase... And prices were already inflated by crypto

If you are going off the inflated prices, this is hardly a price increase at all. 70% is the increase from 1080 Ti release price, not from the inflated crypto prices.
James Grenning's answer to What are your thoughts on Test-driven Development?
Posting with a throwaway for obvious reasons.

I started smoking weed in College. Since then, I've developed a habit of smoking almost daily. Not all day, but usually a few tokes from a vape at the end of the night.

When people ask, I usually reflect that weed has been a very positive addition in my life.

I became VP of Eng. for a well known software company within 3 years of graduating. We did a lot of things right and the company eventually exited with unicorn status. I then left, bootstrapped my own startup w/ a small team, and after 2 years were acquired by a major software company which cemented financial independence. These days, I spent most of my time doing advisory/consulting/investing roles.

I achieved all of this within 10 years after graduating, AND essentially consuming weed daily(usually took breaks when traveling, etc.).

For me, it helps with relaxing as well as creative thinking. The way I describe it is that it removes mental filters and allows you to appreciate something in a new way (that "mind blown" feeling). Sometimes the insights can be superficial, but sometimes they are not.

Nowadays, I am generally pretty open about my use when people ask. What I've found is that it is a lot more common then I used to think. So many founders, executives and otherwise "smart" people use it frequently for mostly the same reasons. I'd have never guessed.

For anyone who might be interested, I'd suggest reading Carl Sagan's essay on it in which he talks about his experiences and insights while high. He actually wrote it under a pseudonym (Mr. X) but revealed his identity through a friend after he passed. http://marijuana-uses.com/mr-x/

This is also just my own opinion - but from my own experience what I've found is that people tend to want to blame someone (or something) else for their problems in life. And generally, marijuana is a pretty good scapegoat to point a finger at.
Oh that ending :(
"Without admitting or denying the allegations in the SEC’s complaint, Rothenberg and Rothenberg Ventures agreed to settle the charges. The settlement is subject to approval by the federal district court for the Northern District of California which would determine the amount of disgorgement and civil money penalties. Rothenberg also agreed to be barred from the brokerage and investment advisory business with a right to reapply after five years. An SEC order imposing the bar will be instituted following court approval of the settlement" [1].

Besides blowing investors' money on lavish staff events, which is a dick move but not necessarily illegal, Rothenberg also invested "$5 million from Rothenberg Ventures' second and third funds in his own startup company, River Studios" [2].

[1] https://www.sec.gov/news/press-release/2018-160

[2] https://en.wikipedia.org/wiki/Rothenberg_Ventures
Nvidia's market cap is nearly 8x that of AMD. Volume =/= profit.
Do you have a source for this "common knowledge"? I've seen plenty of people on methadone do just fine with benzos, especially if they take prescribed doses. I'm not so sure this isn't some bullshit pushed by doctors without evidence so that they have an excuse to stop treating their patients and leave them without benzos in a state where they are forced to either go to the black market or potentially withdraw and die. I've seen a lot of this from doctors as regards to methadone patients, trying to take people who have been on benzos for years or decades off without proper tapering and without a proper reason. It's almost as if they think of methadone patients as less than human, creatures whose lives are not of value. Wait, not almost. Whatever happened to the hippocratic oath?
The bigger tragedy is that there isn't even a good reason to argue over whether or not Oxford commas should be used.

People think there is a good reason, namely that there are some lists that are ambiguous with the comma that are made non-ambiguous by removing it.

However, as far as I've been able to tell, in all such lists the ambiguity is there because there are commas in the sentence serving to mark appositive phrases. If dashes were used instead of commas for the appositive phrase, then the presence of an Oxford comma in the list would not cause ambiguity.

I've seen several writing guides that recommend using dashes for appositive phrases when there are other commas in the sentence. All we have to do is remember to do that (or better always use dashes for appositive phrases), and then it will never be ambiguous (as far as I know) to use the Oxford comma but may be ambiguous to not use it, and so always using the Oxford comma would become the only sane choice.

There was a discussion of this a few months ago here on HN: https://news.ycombinator.com/item?id=16345138
.Net Framework is windows only

Mono is open source port of .Net Framework to non-windows platforms (linux, mac os)

.Net Core is cross platform (like Java but without GUI features for now)

.Net Standard for libraries shared by all 3 above.
Performance of ranged accesses into arrays: modulo, multiply-shift, and masks
I switched to a 5x6 schedule earlier this year and its fantastic. Less traffic in both directions, more time in the morning to exercise and enjoy breakfast, easier to run errands in the afternoon. I also feel less burnt out and more productive during the time I am at work.

I took a small cut in salary to do it, but it was completely worth it.
Plain old MVC.
The curious case of Nothing, the world’s unluckiest band
> Is it cool for Jill to get on Reddit and post the code necessary to exploit the bug before Bo'M has a chance to protect their customers?

It's a trick question. Jill cannot post the exploit before Bo'M has a chance to protect their customers, because Bo'M already had a chance to do so. They just chose to leave their customers exposed by hiring cheap programmers who didn't know their computer science (aka math).

Think that's sophistry? Well, look at the alternative:

In a world where security researchers wait before they publish exploits, it's economically beneficial to cheaply write insecure software, wait for the White Hats to reports the flaws (hopefully before the Black Hats notice), then patch them. I'd argue this strategy amounts to outsourcing security engineering to government funded researchers. Do you want to live in such a world?

Besides, why would Bo'M need to protect their customers?! The customers did nothing wrong, Bo'M did. Therefore, Bo'M is liable for damages. So... let me rephrase your question:

> Is it cool for Jill to get on Reddit and post the code necessary to exploit the bug before Bo'M has a chance to cover their exposed backside?

I think it totally is.
Ask HN: Is it a big problem if Garry Tan thinks he couldn't get into YC now?
See Garry's tweet: https://twitter.com/garrytan/status/1031645030656532480

> @Suhail We wouldn’t have gotten in if we were applying now

I think he meant this as a complement to the latest batch of YC companies, but isn't this a sign that YC has gotten too competitive? Wasn't it originally intended as a way to give the average smart/ambitious young hacker a shot?
I can click anywhere on the video previews to play them, except on the play icon itself. Threw me off at first.
Just out of curiosity - and no offense intended - but have you ever used cannabis?
Visual Studio is a must for 99% of .net jobs, right? I see a lot of praise and comments that it's so good you can't replace it

Do you think they will drop VS and adopt VS Code as the recommended solution? Since it's locked to Windows, bloated and there's no 64 bits version
> The context for this argument is that joining a profitable business carries less risk of being deceived / manipulated and waking up after 4+ years to a reality that is totally different than what you were repeatedly lectured to expect.

> Your response doesn't really refute or address that argument. You are claiming that in the theoretical case that you are given 100% valid information and 0% hype, you should be able to to get a more accurate profit expectation. That's, of course, true.

You need to put yourself in a position where being deceived is fraud. If they show you fake revenue numbers that's fraud. If you don't understand that the real revenue numbers they are giving you aren't good enough, that's not fraud. If they don't tell you every single thing about the business that's not fraud. If they tell you they expect the business to do really well and it doesn't, that's not fraud. Ask the questions you need to get a feel for if the risk is worth it to you and take an educated risk. If they don't give you enough information run.

How much the employer hypes the position doesn't even come into the equation. I don't really understand why you think it's an important thing. Hype is not part of the deal. The numbers and the structure of the agreement are. Of course the CEO is excited about his company why else would he be risking so much to start it? Stop paying attention to emotions and start paying attention to the documents you are signing and the deals you are making.

> What Skype (technically, SLP) did was obviously legal, but extremely shady, and a good example of a savvy business tricking naive engineers. This wasn't innocent: these options that could (and eventually did) amount to millions of dollars were dangled in front of the employees noses since they were mere candidates. And all this time, they were actually worthless.

Again, why are you letting these engineers off the hook for not reading or understanding documents they signed that said in really big letters SIGN HERE IF YOU UNDERSTAND THIS. I can't imagine anything less misleading than spelling out your exact intent in legalese and then following through with it. Engineers chose to pay attention to the cheer leaders instead of the lawyers to their detriment. Why would employees expect Skype lawyers and managers to be on their team?

> Now I'm curious: which are these employers, in your opinion?

Cap table access is rare though I've gotten it a few times, and high level numbers about the cap table are not (# shares, %owned be investors etc.), revenue numbers are widely available, projections are widely available, I dunno man these aren't huge things for early stage employees to ask for, I think most people just usually don't.
The treadmill is the endless debate over whether or not fats vs carbs are more obesogenic. This debate continues ad-nauseum and distracts from more nuanced explanations.

High fat consumption raises inflammatory profiles through mechanisms that are poorly understood. Carbohydrates seem to cause similar inflammation, but this is largely do to advanced gylcation end-products created from fructose, specifically.

Overeating is not interesting. The reason people do overeat is very interesting, and if you hit the literature you find that this is largely driven by damage to the hypothalamus by environmental exposure.
> No species is going to evolve in the next century which will be able to suddenly break down plastic and turn it into energy/nutrients.

Such a species already exists: https://www.sciencealert.com/new-plastic-munching-bacteria-c...

There are also bacteria that can break down nylon: https://en.wikipedia.org/wiki/Nylon-eating_bacteria

I don't understand why people are so dismissive of ideas that are a simple google search away.
A similar situation has already played out with people who deal with chronic pain and opiods. Stricter laws may reduce abuse but they have a chilling effect on prescribing physicians.
Ah this brings back memories. I'm honestly blown away that Amicus only had 3.2M in funding. They consistently got a ton of press (they had at least 2 stories in Techcrunch in 2012 and I remember Seth doing a photoshoot in the General Assembly office). It was also one of a few companies I saw self-combust out of GA, at least this one has become a public cautionary tale ala Knight Capital. Hopefully Topper is doing well
Well, one could make them arbitrarily unfair. Purchasing a carbon credit could reduce a player's own emission score but increase a random opponent's score by the same amount.
I was trying to be generous, but yes. As a card-carrying member of the Jeep and IT communities, yes.
7 million sounds like a drop to settle for, plus likely a small fine.
I like how pollution is handled in factorio
and perfect vs imperfect information - the policy network has to forecast enemy positions and deduce enemy goals. At least in Go you know full game state
A lot of transportation infrastructure is not maintained using federal funds, so the upkeep on bridges and roads varies a lot from state to state and even from city to city. Some larger cities may be able to put enough funds to maintain a bridge, but for smaller cities it may not be a high priority. Your experience may be an outlier in this regard.
Species can evolve very fast - in this experiment from a couple years ago E. coli evolved from minimal antibiotic resistance to almost immunity in about 100 days:

https://www.sciencealert.com/watch-this-amazing-video-shows-...
Glary Utilities PRO 5.104.0.128 Crack and Serial Key Free Download
Intel's spokesman isn't saying "ignore the license, distribution is fine, I promise" - he's pointing out the clause in the license which is intended to allow redistribution.
There's a notable lack of dose-response relationship in most of the collected data, and n=12 for each group doesn't inspire confidence even if in some cases the p-value suggests significance. There are already a lot of measurements taken and included in the table where differences were not that large. Were other measurements taken and not reported in the table? Has anyone attempted to reproduce this?

Most importantly, though, that study doesn't indicate whether the effects, if they end up being reproducible, are caused by BPA alone, or the combination of BPA+sugar. It's well known in other scenarios that toxins, when combined with inflammatory foods like sugar, are far worse than they are in the absence of inflammatory foods.

I'm fairly convinced that BPA is slightly bad, I just think alternative plastics may turn out to have other compounds that are also bad, given horrible diets, and the best solution may be to fix the diet, rather than try to eliminate all toxins related to modern plastics (and the same argument may apply to pesticides). Other toxins from modern living will undoubtedly pop up, and if they all cause different and problematic diseases in combination with bad diets, but not so much in combination with good diets, how much energy do we really need to put into studying and eliminating toxins in a giant game of whack-a-mole?
What books would you recommend to read about ZX Spectrum computer programming?
Hello.
Ask a Datascientist podcast episode
Does someone have a non region-locked link?
If you’re set on the (data science, I presume) PhD, I would suggest a SE internship. The rationale is that you’re going to be deep in DS for a few years so this is a good opportunity to explore another field. And what you learn during the internship (how to write clean code and document it, unit tests, version control, seeing production software) will a) put you in good stead for your PhD which presumably will be code-intensive and b) set you apart from the rest of the data science pack once you graduate. I work with (junior / intern, to be fair) data scientists and OMG, bashing together a Jupyter notebook != knowing how to program. How to get from a trained model to production code is in my opinion a vastly underdeveloped topic in data science. Having SE experience will definitely help you see how the other half lives.
> Taxes don't work to work to change behavior

This is absolute nonsense and flies in the face of established economic theory backed up by empirical evidence. I don't understand why there are so many people in this thread pulling assertions out of their ass like this. HackerNews is better than that.
https://www.health24.com/Medical/Meds-and-you/Medication/Ome...

You're right, the website that had showed up in google that I had used for my prilosec example is either incorrect or using some non-DEA scheduling sytem. I'll use another comparatively ridiculous example and re-edit my comments with the correction.
The problem I'm trying to solve is ideological. I want to see more peace in the world and I think one of the reasons we see so much strife is because too many people are OK with and tacitly approve getting something for nothing. I was accepted with valME.io, a CMS/blogging/forum builder to help spread the idea that trading values makes a much more peaceful environment.
how is it handled?
All you have to do is look at the evolution of beer cans. Over the decades, you'll see a steady reduction in the amount of metal used in them. This isn't for any environmental or regulatory reasons, it's purely cost reduction, since COGS (Cost Of Goods Sold) reduction is a powerful way to increase profits.
I see how that's true on a legal level, but if we're just talking about social and public health impacts, I don't see why the distinction between prescription and illegal use matters here. A three-fold increase in a category of drugs with major health impacts seems newsworthy to me. After all, the boundaries between legal and illegal use are far from fixed. Methamphetamine was once widely prescribed by physicians for weight loss, for instance (and is indeed still legally available as a prescription medicine) [1].

Presumably we can agree that a world in which prescriptions for methamphetamine have tripled might be a cause for concern, right? It's debatable whether this class of drugs has the same abuse and health risks, but based on my own reading and anecdotal experiences, I think they're pretty comparable.

[1] https://resobscura.blogspot.com/2012/06/from-quacks-to-quaal...
I had a great experience with Lufthansa recently. Wasn't using their app, but received very punctual emails with delay and gate information, to the extent that the gate change email came at pretty much the same time as the announcement. Had a new flight, ticket, and gate automatically within about 10 minutes of missing my connecting flight as well.
I was using filtered water.
It's also the most statistically significant gene, in the whole dang genome, associated with Type 2 Diabetes.

And out of a compound library of 20k chemicals, BPA had the top effect on it.

Seems significant to me

Also worth noting that BPA has been shown to specifically effect the occupancy of TCF7L2 at transcription factor binding sites in Chip-Seq experiments.

http://press.endocrine.org/doi/abs/10.1210/endo-meetings.201...

Lastly, before calling someone else's claims psuedoscientific, you may want to do some homework and check your previous biases. We could certainly use someone with your skills to help model BPAs interaction with the Androgen receptor. Might just save millions of lives....
Depends on what the goal is.

300 characters incentivizes driveby remarks rather than articulate conversations.

Twitter also has really bad content enforcement. Not inherent to the format, but it's worth consideration in the interest of practicality.
Why are human faces unique?
2007: https://en.wikipedia.org/wiki/I-35W_Mississippi_River_bridge

75000 other bridges had the same "structurally deficient" classification in 2007. The I-35 bridge was at the 4th percentile for structural sufficiency when rated with 100000 bridges in 2005.

We are sending out engineers every year to look at bridges, and every year they are very nervous when turning in their reports. Whether things get fixed or not is often due to the economic situation at the time the report is made, and the local political will.

What I'm mainly worried about is dams, not bridges: https://www.montgomeryadvertiser.com/story/news/local/commun...
Content marketing is content and marketing, not just marketing, and in this case the content is a good warning to others. Yes, they are trying to sell their product, but they are making a good point, and they aren't shoving their product in your faces. I think you are being hard on them for no good reason.
I can only recommend that you go and do some research on the difference between whole-food carbs and processed carbs, because that is a very unhealthy (and unscientific) view on probably the single most important nutrient for the human body taking into account the fact that carbs is literally what evolution selected as our preferred brain-fuel, not ketone bodies.
It sounds like you consumed too large a dose. Being overwhelmingly high can easily be anxious and uncomfortable for many people.

Even if you think you consumed a small amount, it may have been more than you could handle, especially if you are comparing it to what is consumed by somebody who has built up a tolerance. As the article says, some of what's out there is very potent.