skysight-inc/HackerNews huggingface dataset:
Is it possible that glioblastoma cancer is a result of two different dysfunctions? The glioblastoma tumor in the brain, and an unrelated sequestration of T cells in the bone marrow?

The abstract states that the loss of S1P1 is tumor imposed, but not having access to the paper, I don't know what they mean by that.
The second web site I ever built (and then sold) was built in a B&N cafe.
There are many comments that don’t say that, however.

The USA is still a great place to do business if you want to make money. My only arguments against China is that the system is more rigged against foreigners from making money there.

The moral arguments are a distraction, though they are mostly true. Yes, China has third world problems, yes the USA has first world problems. Whatever, the world is an imperfect place.
As part of my current job I have to read about 100 - 300 pages of technical material a day. I still read for pleasure, but less so when I cross that 300 page marker for a day.

The worst was when I had to review ~ 10,000 pages of material for a presentation. I wasn't reading all of that -- I maybe read 1/10th in great detail, and skimmed half after I determined it was relevant -- but even so, for a couple of weeks after that I didn't read for pleasure at all.
I see - like around the inside of a torus.
NSA Documents Reveal Network of Agents, Details of Coup and Voice Matching Tech
It's wrong that assisted suicide is illegal. The only humane thing to do here is let her pass in peace.
The next message in the thread adds to the insult https://marc.info/?l=openbsd-tech&m=153434075003703&w=2

What's funny is that LWN, a Linux news outlet, might have:
Original title (too long)

328 NSA Documents Reveal “Vast Network” of Iranian Agents, Details of a Key Intelligence Coup, and A Fervor for Voice Matching Technology
Thank you!! Everyone needs good Indian food :) Hope you try it out!
I say it's great. Hopefully more people concerned with owning their content will move to a static blog generator or even WordPress.
They didn't mention in which state was the donor before her grandmother agreed to donate her face. Was she already dead from the overdose? Did they just take the full skull to the hospital?
The bottom line is that it's not possible to compete on price with Amazon. Amazon does not need to operate storefronts (although ironically it is starting to open them), has a massive selection, and offers very fast shipping.

Amazon also does not need to deal with shoplifting, which is a huge problem for bookstores. I worked at a Border's Books back in college and it was just amazing how many DVDs were stolen. People would fill backpacks with them.

The only way to outcompete Amazon is by becoming a niche player, not by becoming a worse version of Amazon, which is the outcome of the Barnes and Noble strategy.
Escape from the USA – Renouncing US Citizenship Is an Extremely Tricky Business
Lack of Correlation for Bitcoin Provides Little Relief as Markets Sell Off
"everything sucks and everything is broken"

Well, looking at all the chips I've bought in servers for the last 5 years, they are not wrong.
Thank you! Looking forward to your feedback + will definitely update the nutrition info soon!
Please don't stoop to personal attack, even when another comment is annoying.

https://news.ycombinator.com/newsguidelines.html

Edit: you've posted uncivilly elsewhere too, e.g. https://news.ycombinator.com/item?id=17766899. That's not allowed here, and we eventually ban accounts that do it. If you'd review the guidelines and post civilly and substantively only from now on, we'd appreciate it.
Do No Harm or AB Testing Without P-Values
Doesn't the brain start to die after 10-15 minutes without oxygen? How could he possibly go that long without breathing without suffering any brain damage? I remember when David Blaine was going for the records, the biggest concern was that he would irreversibly and severely damage his brain.
Thank you so much for pointing that out! We will fix it ASAP.
There is no regional loyalty when dealing with Industrial Profit growth.
Actually, that's pretty low for an Indian dish. Many of the dishes (especially south Indian) have way above this amount o sodium. It probably makes sense to take that much sodium when living in South India as many places are hot and you will end up sweating the sodium out anyway.
Yeah, as kerbalspacepro says, the valuations all seem random to me. The salient point in this article, to me, was that workers' quality of life and pay has only gone down with time, whereas CEO and board stakeholder quality of life and pay has only gone up. I don't think I agree with mandatory capping of CEO salaries, but I do agree with companies making $1billion+ in profit per year playing by different rules than smaller companies to close the wage gap.
Analyzing the Legal Issues with Serving Formal Papers on Social Media
> a problem of their own creation...

The DoD didn't invent war. It doesn't declare war. It just fights wars.

Who sends our young people to be blown up? Our elected leadership.

So we all made this problem.
> Monopoly is if one corporation owns an entire market.
This isn't quite right. Traditionally for a company to be a monopoly it isn't even required it control a majority of the market. It has more to do with the company being in a privileged circumstance in a market and explicitly using that privilege to bolster themselves or suppress competition in the same or related markets.

An example is Microsoft with Netscape. Microsoft was sued with anti-trust laws not because IE or Windows owned the entire market, but because Windows gave Microsoft a privileged place in the web-browser market that they abused.
Smaller stores in higher traffic areas, a few bigger stores that serve a larger suburban metro, and they need some exclusives and maybe a paid membership program.
This is true, but it doesn't mean software can be delivered at any point in the development process.

Something like a novel is (hopefully) shipment-ready at most points from the first draft on. A full rewrite might happen at some point, but much of the development process happens after the first draft and can be interrupted with minimal cleanup. If you've only copy-edited half of chapter one, you can still finalize those changes and ship without trouble. And, you're unlikely to get 95% of the way through writing and discover an issue in Chapter 10 that invalidates chapters 2-6. (This does happen, especially with mystery novels, but it's not the standards outcome. It's much more likely to just hit a problem that makes you want to rewrite, rather than actually breaking the piece.)

A lot of software has a high percentage of work happen ahead of the MVP, and even if progress past the MVP is done while maintaining a working state, the individual tasks don't tend to be interrupt-able. If that shipping system is instructed to handle bulk-loading of 50,000 orders, fixing the manual zip code issue is probably still an all-or-nothing task. And, of course, there's a high chance of invalidating past work. If a contract comes in that requires multi-user ownership of orders, that might break invariants across the entire database while still looking to the buyer like "just adding another user to my order".

Pretty much any field has some minimum unit of work to move between acceptable states. You might print a novel mid-editing, but not while a sentence is half reworked. You can launch a new car model with fewer units finished than you'd like, but not (easily) with contracts for dealers that will be unfulfilled, and certainly not if you find a problem with the airbags.

Software development frequently gets planned like creative or social work which generally has small minimum increments and few catastrophic surprises, but ends up playing out more like construction or physical manufacturing where unexpected failures are likely and shippable states are noticeably far apart. Hence death marches, outright broken releases, and a lot of the other issues the field is infamous for.
Take a bus. Buses are cheap. Nobody gets evicted without warning. You have time to prepare.
Another vegan chiming in to say I assumed these weren’t suitable for me based on the name because buttermilk is an ingredient I see and think, “damn :(“. Veganism is very much about identifying red flags that make something unsuitable, so any reference to a non-vegan product is going to immediately turn off a non-zero portion of vegans because they won’t search out the ingredients to discover it is vegan.

A key part of a manageable vegan life is building a database of what you can consume that you enjoy and using that to drive choices, so if you can get vegan customers buying your food and enjoying it then they’re going to be stickier customers. I am a very loyal customer to my favourite food brands out of necessity, as are my vegan friends.

That said there’s certainly a double edged sword here in that there are some non-vegans who see “vegan” and are turned off but given Indian food is so often vegan I don’t think this would be a concern in your market. Although the name is cute, it’s definitely misrepresenting your product to a growing portion of your potential customers. If you stick with the name, regardless of marketing, you’re going to lose vegans, because many won’t look beyond the name because that’s a necessity for getting by.

There’s a few companies in the U.K. doing intentionally vegan ready meals (e.g https://allplants.com) and there’s a growing market for vegan ready meals (we are as busy/lazy as everybody else), so I think it’s worthwhile to reconsider the name, but also it’s a great name so maybe you can be the company to get vegans to look beyond red flags. Your product seems absolutely great for my needs and would, assuming they’re enjoyable to eat, integrate into my life well. Good luck!
This makes no sense. Rents are not linked to the costs of property. They are fixed to as much as local people can pay for a home, roughly 50% of typical household income everywhere in the developed world.

The ROI is the +appreciation + rent - expenses.

If the property depreciates you have least return on investment. There is nothing you can do about it. You can't increase rent to compensate, people can't pay more rent. Your reasoning is absurd, if you could increase rent you should be doing that right now already.
please no all-caps titles...
Trailing period gets stripped

https://en.m.wikipedia.org/wiki/National_Federation_of_the_B....
"in my experience typically I/O is the primary bottleneck for database loads"

Not when you have potentially neatly 3TB of memory cache.

Of course it all depends on the dataset.
this is what I always envisioned progressing towards, a back scatter machine with computer interpretation of what is seen to protect the privacy of individuals while exposing concerns. probably one of the biggest failings of the TSA machines is that there was not enough computer enhancement of the images to remove what would be embarrassing to many.

the skeletal information presented would not even have to be accurate to get the job done. it could be a whimsical interpretation with all unidentified items highlighted
Your use case for TastyBit makes total sense. We're hoping to be a go-to option for a normal meal at home when you don't want to spend the time/money/energy on making a meal from scratch.

We are starting with Indian food but will hopefully be expanding to different cuisines, too!
VKMS Coming in Linux 4.19 Is One of the Best GSoC Outreachy Projects of the Year
Addicted? Nicotine-free JUUL pods
This doesn't work because au is a diphthong (a gliding vowel). In Bernese German you could pronounce üu, but not in Standard German.
The Netherlands has a system where vacant properties may be occupied by squatters after they've been empty for a year. There's an active squatting scene in Amsterdam, particularly OT301 (an abandoned cinema, now an arts centre).
It's definitely a subjective thing! It's hard to find authentic Indian food that tastes good, is easy to make, and affordable. That's where we come in :)
Introducing the Windows Pseudo Console (ConPty)
> You are wrong and you should feel bad

Attacking someone like this will get you banned here regardless of how right you are. In particular, please don't use internet shaming tropes on this site. There are many ways to correct misinformation civilly and substantively; please use those instead.

https://news.ycombinator.com/newsguidelines.html
Great article.

If you could over the 8008 and 4004 that'd be awesome :D
Non-interactive version of the article can be found here: https://www.nationalgeographic.com/magazine/2018/09/face-tra...
Note that, contrary to popular understanding, it isn't even established that quantum mechanics is indeterminate or not subject to strict cause-and-effect.

It's indeterminate according to the mainstream Copenhagen interpretation, but de Broglie–Bohm theory [1] ("pilot wave theory") is an interpretation that is entirely deterministic, and its assumptions result in exactly the same final equations as the Copenhagen one. But every particle always has a definite position+momentum and there's no notion of wave collapse or philosophical trickiness of what constitutes an "observer". For more on the historical reasons why Copenhagen became mainstream and de Broglie-Bohm didn't, see [2].

[1] https://en.wikipedia.org/wiki/De_Broglie%E2%80%93Bohm_theory

[2] http://qr.ae/TUNXvC
GSoC VKMS Final Report
I sometimes wonder if I could sell Rhinoceros trampling preventative services to major US transit agencies...
Grab the stdout of a python script that calls a webservice?

There's no ruby equivalent of googleapiclient?
they're not links, as they don't link off to other pages - they'd be buttons, with event handlers attached.
Yes, it's true they're close. The lazy FPU state restore bug is similar, too. Though, Meltdown did apply to some ARM 64-bit processors.
The strongly libertarian/anti-regulation folks really don’t seem to have an answer for this. And it’s where thier whole philosophy falls down because it so fundamentally ignores human behavior so it’ll never work.

Sure, imagine you could just pull a trigger and one day remove all regulations. Then see what happens. Buildings will collapse, people will organize to require building standards. Quacks will kill patients. People will organize to require testing of drugs. It’ll all just build up again. Rules (however you want to define and manage them) exist everywhere, they’re an unavoidable consequence of society.

I think the strongly libertarians/anti-regulation folks need to come up with solutions to over regulation, bad regulation, regulatory capture, etc that work within a realistic understanding that humans are humans. Then they might get somewhere, propose some changes that help everyone in the process. (Though I sometimes think there’s a contradiction there that if you do understand other humans you don’t tend to end up so far down the libertarian scale in the first place)
Your brain still receives oxygen without you breathing.
there is a moral valence to this topic, and that ought to be expressed somehow.
> don't have any preservatives

Just what I was looking for. Definitely going to use this service.
Interactive Hyrule Map for the Legend of Zelda: Breath of the Wild
Does anyone know why most (if not all) face transplant have such wide jaw line ?
Looking at how those wars have ballooned our national debt, I disagree that we can afford those follies
From the amazon link to TastyBite's packaging, it looks like they also don't use preservatives (It's explicitly mentioned in the packaging that no preservatives are used). Good luck with your startup, but their shelf life of 9+ months doesn't seem to be due to use of preservatives, it could be due to the packaging process.

On a relative note, there are tons of such products in India and most of them taste sub par to home cooked food. One exception I found was Butter Chicken I used to buy regularly when I was spent some time in Newyork few years ago. You just have to freeze it until you open and then, heat it in microwave and ready to go. It tasted very good, but spoiled my stomach (I am bearing the burden even till today) due to the usage of preservatives. Anything that doesn't use preservative is a welcome addition.

One more, when you mentioned sustainable packaging, what does it mean? Is it paper or bio plastic? If so another +1.

https://www.amazon.com/Tasty-Bite-Chickpeas-Tomatoes-Microwa...
Not to mention a "fast hash" is inherently insecure, so the author must be mistaken: He should be trying to add arithmetic operations rather than remove them.
working link: https://en.m.wikipedia.org/wiki/National_Federation_of_the_B...
Unfortunately, I have no sympathy for the company, as they recently laid off much of their full-time, expert-level employees for a quick and dirty buck, likely accelerating their demise. It is a shame, though, because in some places - despite the rise of local bookstores - they are the only place left to not only _buy_ books, but a place to "hang out" around books. They also host readings for smaller writers. Yes, libraries also fulfill this function, but where else can you bring your kids, buy a coffee, look at/buy some books or magazines and then go to the nearby mall?

I've always been amazed at how well-stocked B&N stores are, even in small towns like Fresno, CA. Likely one of the only places to buy a philosophy or classic literature book in the whole town.
Tesla 'to be probed by regulators' over privatisation plan
man, a lot of words to say nothing...
Bill Burr says the easiest way to get Americans to give up their rights is through fear or free t-shirts.
I'm aware that some areas have very little to no affordable housing. But i'm also aware that if you move to a city 30 miles or so outside of those areas, housing gets affordable again. Can't afford SF? Go to Fresno. There's jobs, housing, and bus tickets are less than $20.

I'm totally willing and interested to listen to arguments that this sort of poverty is a real trap and in some cases i'm sure that it is. But in the argument you make, you yourself saw an exit route (enlistment) and you took it. That sort of resourcefulness is exactly what seems to be missing from most of the arguments that I see about people being trapped.
Multi-tools - for when you need to do a mediocre-to-bad job with lots of different things!
This was my favourite answer.
Right idea, wrong scene, this is the one with an actual gun:

https://www.youtube.com/watch?v=cWIHv7a6luY
Is it skill deficiency or wage deficiency?
Anything really, it's always good stuff :)
The Ipe extensible drawing editor
The new Indium (a JavaScript development environment)
The trade-off with a multi-tool is additional complexity, more difficult maintenance, it's heavier, takes up more space, etc.
Seems to me she wants to live. I am not sure anyone would go through with that surgery if they did not want to live.

Edit: Reading more about the story. Her suicide attempt was entirely impulsive and not premeditated at all.

> "I never thought of doing that ever before, and so on hearing about it, I just didn't know how to handle it," she told National Geographic. "I felt so guilty that I had put my family through such pain. I felt horrible."

This is not an appropriate story to be talking about assisted suicide as it does not apply what-so-ever. This is more of a teenage depression / gun control discussion if there is to be any relevant meta-discussion at all.
> It's far, far too easy for people to treat technology as artifacts handed down from the gods that can only be passively accepted.

Too true. I usually phrase the same sentiment as bemoaning how people treat tech as if it's some magical black box into which they cannot peer & tinker.

Of course, I feel that same way about other things, such as automobile engines. I know it isn't a magical black box, but it may as well be.
How this compare with https://github.com/bloomberg/comdb2 that adds stored procedures using LUA scripting language and decimal types ?
You can absolutely have a career in construction, as I know many people who have.

The challenge is health. It's a very demanding line of work where you have to carry weight, wake up in the early morning and work in the cold. People don't want to work like that. It's very hard on the body and you're broken when you reach your 50's.
The humane thing is to let her choose what to do. But I agree that assisted suicide should be an option, under the supervision of trained psychiatrists and science-based protocols.
Hey!

I'm am an expat who lives in the UK. I'm from India as well. $24 for 3-4 vegetarian meals seems really expensive, will you adjust pricing as you scale?

How do you plan on preserving taste and the "home cooked feeling" as you scale? This might be an absurd question at this stage, but a friend and I who wanted to get in this space couldn't come up with a good answer.

Personally, I just cook a lot of food whenever I cook so that I am able to do a couple of meals. I've recently considered having a soylent for dinner and I just ordered my first pack of Huel. I can cook whenever I want to eat really authentic food.

Here in the UK a lot of house wives provide a tiffin service. Is there something similar in the US?

Great website. Nice story. I wish you luck :)
Yup, they're starting to kill off the CBDM positions as well. No severance either...
Stocks are valued primarily on future earnings potential. This Act would significantly dilute the shareholder control by mandating 40% employee elected directors, and mandating they consider the interests of employees, customers, and communities in all decisions.

Imagine you have a factory in the Midwest hemorrhaging cash (or even just break even) but other profitable locations. Right now, you'd most likely shut it down and consolidate, move, or outsource that work.

Your ability to do so is impeded under this act, by employee elected directors and/or activist investors.

The result is less profit potential. Knowing that every company has to make these type of decisions (including benefits), their earning potential is reduced, and their valuations will tumble due to it.
Thanks for sharing this. Definitely the glimpse you don't see in the business section, but the result of corporations that solely answer to shareholders.
It is if you apply it to China and not to the U.S.
Which wouldn't be a problem if the hotel made an official policy of "guests may call the front desk to verify the security guard, both of whom will co-operate in verification" (and enforced it).

The problem, as I read it, is that the hotels started more intrusive checking by security guards without considering or providing for the needs of some guests to be less than fully co-operative (for good reasons).
He does start with a lung full of pure oxygen.
The answer to your question is in the site guidelines: "Comments should get more civil and substantive, not less, as a topic gets more divisive."

https://news.ycombinator.com/newsguidelines.html

To the extent that people are fulminating rather than saying anything substantive, and reacting ideologically or tribally rather than thoughtfully, they're crossing outside the scope of what this site is for. Heated rhetoric, grandiose generalization, and angry name-calling are the kind of thing that mark this distinction. Your comment at https://news.ycombinator.com/item?id=17764244 is an example of the kind of thing that clearly moves the needle into the red.
Does East Africa have the infrastructure and law enforcement necessary to compete with China in manufacturing?
Google Coach wearable AI assistant may motivate you to get in shape
Hey man, as someone who also formerly worked in a different industry, thank you for raising this question. The longer I'm in software development (six years now) the more confident I am that all the varying rationalizations for this stuff are complete BS.

Please keep raising these questions so that those of us who don't believe in bizarre guru-based project management approaches can have a home in this industry.