skysight-inc/HackerNews huggingface dataset:
>"knowing the amount of effort expended in the rest of the field of medical research today ... it is indeed surprising that nobody has bothered to even try to produce a human body model. The feat probably wouldn't even require genetic engineering."

You seem to think that effort should translate into understanding. Nature doesn't work this way.

In my opinion, most effort in biomed has been wasted due to poorly designed studies, which is due to NHST (null hypothesis significance testing; ie, testing a null hypothesis rather than the research hypothesis), and all the BS that procedure entails.

So the real reason no one is trying to develop "a fully functional human body model" is that such a model is not even visible on the horizon for a single cell, or even sub-cellular organelle.
No real minuses discussed here so I thought I'd share some from my FP journey, which was SML -> OCaml -> Haskell -> Clojure. Each had its own sort of enlightenment, both in strengths and weaknesses.

IMO an under-appreciated weakness of Haskell is its culture of poor code quality and engineering practices, e.g. in how code is structured, (not) commented, or named.

Example, inspecting a graph in Haskell via fgl, we encounter the foundational Decomp type [1]:

type Decomp g a b = (MContext a b, g a b)

`a` and `b` are types, and in languages geared towards engineering, we would give them actual names: a is a NodeTag and b is an EdgeTag. But in Haskell it is customary to not provide this information, instead falling back on the type checker to ensure the code is consistent. There is not much effort put into useful naming: map vs mapM vs mapM_...

Second example, the simplex algorithm [2]:

addart :: (Num e, Enum a, Ix a, Num a) =>
Array (a, a) e -> Array (a, a) e
addart a = array ((-1,0),(n,m+n)) $ z ++ xsi ++ b ++ art ++ x
where z = ((-1,0), a!(0,0)) : [ ((-1,j),0) | j <- [1..n] ] ++ [ ((-1,j+n),a!(0,j)) | j <- [1..m] ]
xsi = ((0,0), -colsum a 0) : [ ((0,j),0) | j <- [1..n] ] ++ [ ((0,j+n), -colsum a j) | j <- [1..m] ]
b = [ ((i,0), a!(i,0)) | i <- [1..n] ]
art = [ ((i,j), if i == j then 1 else 0) | i <- [1..n], j <- [1..n] ]
x = [ ((i,j+n), a!(i,j)) | i <- [1..n], j <- [1..m] ]
((_,_),(n,m)) = bounds a

this code is astonishingly compact, but totally impenetrable. It has no comments, useful names, etc. This write-only code is typical

Haskell and its culture have significant weaknesses from an engineering perspective.

1: https://hackage.haskell.org/package/fgl-5.6.0.0/docs/Data-Gr...

2: https://hackage.haskell.org/package/dsp-0.2.4/docs/src/Matri...
I'm not sure if either is appropriate. Bitconnect is worth nothing, so no matter how many bitconnect coins were lost, they would be worth $0 not $3B.

The title seems almost unrelated to the article. The title refers to money lost in the bitconnect ponzi scheme, but the article is mostly about kidnapping schemes worth much less money, and that demanded payment in bitcoins.
In cases where it is possible to conceive of an experiment being repeated in the future

That's just the thing: Bayesian probability is emphatically not about an experiment being repeated in the future. That's the frequentist interpretation of probability.

But, don't make an appeal to the Dutch book argument in a unique one-off case where no one has anything at stake other than free publicity which they have chosen to pursue by counting some stuff and dividing those counts by some numbers and stuff.

???

The Dutch book argument shows that rational people must have subjective probabilities which behave according to the axioms of probability. I don't see the relevance of your statement here at all, particularly the bits about "anything at stake" and "free publicity".

And what are you trying to say by the phrase "counting some stuff and dividing those counts by some numbers and stuff"?
Designing the Cassini Tour (spacecraft orbital design, 2009)
I am glad it helps, everyone have tough period, some you can't just get out alone, glad you made it, and hope everyone in the same situation will do.
They are tightening them with RERA act etc. If you have noticed income tax and GST registration are sky high. So much that government had to reduce the GST. India is and will become cash free. Sooner or later.
Kidney failure = your kidneys are now a clogged shower drain that also lets protein and blood go into places it shouldnt
Interesting alternate viewpoint!
I'm not in the US but last time I've checked the top federal tax rate today is higher than it was in the Reagan era.
The federal income from taxation (as % of GDP) remained fairly since WWII stable: https://en.wikipedia.org/wiki/Income_tax_in_the_United_State...

But sure i'll hear you out what tax brackets do you think we should implement? where do you put the cap?
I don't think so - when you look at historical data, labels change. Seems like Poland is simply a significant actor in this particular attack.
Treasury Redefines Tax Cut Restrictions to Give Wealthy Even More Breaks
I'm pretty sure the original rule recognizes no exceptions, and certainly not on something so broad as an entire category. It may be that much narrower exceptions could exist, but future-proofing sounds like it could simply be justified as a feature actually needed now, if not just good overall coding practice [1].

The danger of allowing such a broad exception is that it doesn't take a huge leap to imagine a situation where it's used as permission to do something like a custom implementation of ACID in the app backed by a NoSQL key-value store (or "sharded" MySQL, before NoSQL was a thing).

[1] YAGNI isn't a standalone rule but one of many in the "XP" collection. Any one of them, out of context, in complete isolation, could just as (if not more) easily require a long list of caveats/exceptions to make sense in the general case.
I think this fails the base rate fallacy test; there are lots of times when mucking with an ecosystem hasn't caused problems, but nobody talks about those.
Computer Maintainence
> I have no business of my own to withdraw from China or Russia.

That's probably untrue from the face of it, just from the amount of products and goods that are produced in whole or in part in China.

In fact, for many products, good luck finding a choice that doesn't directly or indirectly lead to money ending up in the coffers of the Chinese businesses, which is just one hop away from tax revenues of the Chinese state.

But, like, everyone also directly buys or depends on gasoline, which indirectly funds plenty of unpleasantly authoritarian regimes.

What I'm curious is how anyone can have clean hands when everything is just shades of grey in a global, fully-connected economy where everyone is just a few hops from everyone else.
Computational model? No. As one of the other commenters in this thread has already said: model as in model organism.
The Luftwaffe Storch was the granddaddy of these designs:

https://en.wikipedia.org/wiki/Fieseler_Fi_156
Are there any good guides out there for setting up Sphinx like Google/Amazon's API? I'd just rather not schlep audio data off to an unknown party when I have plenty of excess compute on my KVM cluster, accuracy isn't particularly critical.
Does that frame of reference make sense for a recycling program though? The deposit system is a zero sum system that isn't designed for the purpose of making money - the deposit is to discourage consumers from throwing recyclables away and instead get their money back.

It seems like more of a side effect that low income workers use it as an income stream more than anything. It's like a metaphorical form of picking up loose change that others have dropped and deemed not worth their time to pick up.
> If you lived west of the Rockies, you could get Coor's (giving it a forbidden-fruit magnetism for everyone else.)

Funny thing is, this same "forbidden beer" thing played out again in the 2000s with New Belgium beers in general, and Fat Tire in particular. Nowadays you can find it just about anywhere, but in 2002 it was tough to come by east of the Mississippi.

Once in college we took a seven hour road trip to West Memphis, Arkansas, because there was a rumor going around that it could be found there. Sure enough, we found three cases in a sketchy liquor store. We made those beers last. :)
What about 'practice what you preach'?
I get my news all over. Most prominently, NPR, BBC, Reuters, and France Info.

But I don’t think it’s hard to find, you just have to look for it. Lots of contemporary debates have a strong element of this. For example, the fight over “sanctuary cities” is all about this. Gun control and abortion often involve questions of whether those things are better set at the state or federal level. A huge amount of education policy debate is about how much the feds should dictate. A big part of health care reform is whether it should be done at the state or federal level. Net neutrality is turning into this now that the feds have given it up. I have a hard time thinking of anything domestic where central versus local control isn’t a big part of the debate.
Whataboutism is a really poor argument. The history of the West is full of atrocities, but that doesn't somehow excuse the Chinese government from current human rights abuses. Nor does it mean that I as a Westerner do not have the right to criticize the Chinese government. In fact we have an obligation to condemn human rights abuses wherever they occur.
So far, I have not heard anyone who has found any security holes and I'm active in the #WireGuard IRC channel with 300+ users, where many have looked at the code. There may be some unscrupulous hacker who has reviewed the code and found something but choose not to publish it, but it may also apply to WireGuard's source code.

A security hole in WireGuard's wg-quick that many use to establish the connection is that it allows the .conf file to download and execute programs without asking the user, and this feature is enabled by default.

This is basically a good feature and allows admins to run custom software as soon as the connection has been established.

However, it allows an evil (or NSA-hooked) VPN provider to issue .conf files to infect the user's computer with malicious code because users of VPN services rarely review the .conf files.

TunSafe has the same feature but it is disabled by default and requires Admin privileges to enable it.

I like that TunSafe seems to have more restrictive security settings as default, though it may not be appreciated by hardcore users.
The first response posted is absolutely hilarious and perfectly summarizes basically every educated person's attempt to get tech support from any large company.
Mentioned in a previous HN thread where I contributed this comment:

https://news.ycombinator.com/item?id=15830348
Thunderbolt is a quite under-documented protocol. I realize it's proprietary (for now) but even by those standards there is almost nothing publicly available. Maybe Intel doesn't want people to know that a dual-port "40 Gbps" Thunderbolt controller only has 32 Gbps of PCIe bandwidth total and according to this question each port only supports 22 Gbps. This may explain why real-world benchmarks don't show performance anywhere near 40 Gbps (although TB3 is generally still faster than any other consumer protocol).
> Reading Gödel, Escher, Bach? Intellectually positive. Reading a Harlequin novel? Intellectually neutral or negative (opportunity costs).

Not according to the brain scans. The content doesn't matter. It's the act of reading that strengthens the brain. If you manage to get more out of it than that, well that's gravy.

> Regarding books vs video

Maybe this was intended for another comment? I haven't said anything about video. TV is not youtube. The consumption patterns are different.
I love skateboarding over them on the KiKi song.
What more is there to say other than it's just wrong. Whilst interesting technology, can us humans really be trusted to do the right thing with it just yet, if ever?
I mean, if that's your logic about this, does the system even matter? If we're eventually gonna hit a stopping point that reverts us back to starvation then it seems like everything is an equally bad choice.
+1 If you consider the hours of playing tournaments professionally it is a lot less than a programmer's take home.
A significant portion of Q2 GDP was China pulling forward commodities purchases prior to tariffs going into effect.
Could you perhaps make a simple but user-friendly website that lets people convert their epubs?
You are right. Nissim Taleb describe as no skin in the game. I see it especially strong when all ethical concerns about Google/FB etc disappear while discussing huge salaries, bonus and stocks.
A public inquiry where people actually point fingers seems pretty wild / dramatic.
Thanks! I was very misinformed!
Introducing 12for12, Philanthropy-as-a-Service
> environmental laws would be much harder to practically enforce ... and then offer high/sport/cruise modes that runs the engine at full capacity otherwise

Only if your company is ready to willfully break the law.

The vehicle ought to, at the time of testing, meet or exceed all relevant standards, and not have a user accessible option to circumvent the standards.
As a very rough ballpark, hard drive cost was around $1/GB, putting a single copy of everything around a half million dollars. Honestly quite a bit less then I expected for back then. Of course there are tons of other costs, but still not unreasonable for a Walmart size company.

http://www.mkomo.com/cost-per-gigabyte
This is a tiny bit of code, that offers a lot of functionality, including claims of safety. It does not have a single automated test to prove anything. =(

Sure, douglas is an amazing engineer, but how about teaching kids these days about the importance of testing?
He might not have a job now and at 52 maybe never again, but he needs to look at the positive side; likely due to labor offshoring a new Hyndai vehicle might end up being 30% cheaper.
I don't see a specific line item for sandwich boards on the publicly posted fee schedule[1]. But $30,000/year is a good 2 orders of mangnitude more than anything else on that list.

[1]: https://www.cityofchicago.org/content/dam/city/depts/bacp/bu...

edit: Looks like they're just straight-up illegal. Some aldermen (including one who's pretty good at getting things done) are working on that: https://blockclubchicago.org/2018/06/28/a-frame-sandwich-boa...
They don’t explain how the lasers repel the birds. Especially in the day you’d they wouldn’t notice green dots on a green background and it doesn’t seem like that would scare them.
Opus Magnum had some puzzles that were rather tedious, I think maybe more than average. There's always a point in these harder puzzles where you know what you need to do and then slogging through the execution is daunting on its own.
Project Natick – Underwater datacenter with live cameras
:) No, I am not. I trekked to Mt Everest base camp last year and I stayed there the first night after starting at Lukla.

Are you from Nepal?
This is perhaps the greatest example of Poe's Law I've ever seen... I... hope?

Otherwise, I genuinely don't even know where to begin...
The Lessons of the Seattle Plane Crash
Wow, looks awesome. Has anyone visited, by any chance?
…that he might actually be able to buy without having a job once korean regulators give the green light for would-be investors to pour their and their friends/families life savings into making unsecured p2p loan platforms popular.
I think you are misunderstanding the benefit of having symmetric reach by the page.

On AArch64, you can define a 2 GB contiguous slice of address space, built up out of whatever page size you find convenient for your system and plant a relocatable binary into it, up to 2 GB of size. Any instruction anywhere in the last page can reach any address in the first page, and vice versa.

In RISC-V, if you try to do the same thing, you'd find that while any instructions in the last page can reach any address in the first page with room to spare. But some instructions in the first page cannot reach portions of the last page.

Sure, it doesn't matter most of the time. It isn't ever really an obstacle in practice for the feller writing application code for the platform. But the linker has to be aware of it in the 'medium' code model as a special case for just this particular platform. Somebody had to write that special case to work around the hardware.
No one knows who Satoshi Nakamoto is, if he's alive, and whether he will use his bitcoin in the future. He could move the market if he chooses. At one point he was an oligarch, correct? He had money and political power as far as Bitcoin is concerned.
Birds that can fly blind? They call them bats. They use echolocation. Some species also like berries.
Without an IOMMU it's a gigantic security risk. I don't know that withholding documentation does anything to slow that down in practice but I wonder if it's somehow part of the obscurity.
Sending Fax Back to the Dark Ages
And also other, poorer 52 year old men will have jobs.

Which doesn't mean it doesn't suck for him.
Illegal, unethical and immoral are all separate things. Its possible to be doing something legal and still be unethical or even immoral.

Idk whats more disheartening, the censorship apologists in the comments or google shareholder/leadership willingness to be immoral in the pursuit of profit.
How to Protect Workers Without Trade Tariffs
More Performance at the Edge--Scaling takes on a whole different look
Adding to this offtopic chain, there's a game based on a group of people in town and one or more evil doers.

http://www.blankmediagames.com
great, so it's an app that broadcasts your clipboard contents to all bad guys on your network.
Increase performance while reducing costs with the new App Engine scheduler
"Abiding by local laws and regulations" is a veil behind which international companies hide, claiming lack of responsibility for actions that many of us would consider unethical. Just as with Yahoo's outing of Chinese dissidents[0], at some point companies in China (like Apple, now hosting iCloud data in Guizhou) are going to be forced to hand over data to the Chinese government in order to "abide by local laws". Cue the "but the NSA collects all our data, anyway" arguments..

[0]https://en.wikipedia.org/wiki/Criticism_of_Yahoo!#Outing_of_...
Agree, the clipboard contains a treasure trove of sensitive information.
More whataboutism,
I read "skin in the game" it was ranty and poor, but beyond that, there is absolutely skin in the game for everyone when we are discussing a massive country falling into totalitarianism.
It is perfectly fine argument for calling out hypocrisy though, and I think that is the main point of it.
> On the other hand as long as batteries are heavy, ICE's will have a place in aircraft, and I would think the OP's technology could be huge for helicopters.

The future of ICEs for aircraft is turbines, not piston engines with digital valves. Most commercial aircraft are already turbines; the only thing holding them back for light aircraft is cost.
I upgraded to the iOS 12 beta a week or so ago on my 6S+. I can say without any doubt that it is so much faster that I feel like I have a new phone in my hand. I honestly never thought an upgrade could make this much difference.
I've got a similar problem with chipmunks and the Marian plums I grow. The chipmunks start raiding the trees when the fruit just begins turning yellow and becoming fragrant. But all they do it take a bite and throw the still somewhat green fruit on the ground.
In this case they're pointing fingers for outsiders to watch.
Bitmain sold most of their Bitcoin for Bitcoin Cash
I have thought about that. I will do if there's demand since I would really love for people to be actually using this and right now only developers can use it.

Will require a bit of simple front end work. For example, translating an epub really needs to involve the user (which is currently available in the terminal) since it's very difficult to automatically translate names.

For example, "April" can be a month, a town name or a person's name. It needs flipping if it's a name, but not otherwise. Even context sometimes doesn't help: "We were worried about April."
Well, he did come back to create the game popular TV game show Hollywoo Stars and Celebrities: What Do They Know? Do They Know Things?? Let's Find Out!
DSMock: Fixture-injector for appengine datastore, based on YAML format
I watch a few aviation YouTube channels and this plane has popped up a few times. I had no idea of the story behind it, that is super cool!

Minor article nitpick, bushplanes are more like the Land Rover Troopy or Enduro motorbike bike of the sky, and not at all like an SUV. SUVs are lumbering, fragile and impractically large people busses, often with all the luxuries you can think of. Bush Planes are nimble, barebones, and pragmatic vehicles of utility. Getting hot? Crack the window. Luggage? Not today sorry, the air is too thin.

Except this one, still a bush plane, just an incredibly powerful one!
Which boulevard and goose products have decreased in quality? I have a friend who managed to tell by tasting blindly when they moved Honker's production to New York, and even he said it got back to normal a month or two later.

Duvel is absolutely a best-case scenario for a brewery purchase and it seems like Boulevard has been able to continue doing what they do well.

Ballast Point is one of the only breweries I have lost all interest in post-buyout.
Doctor here. Probably not misdiagnosed. It's a pretty solid diagnostic evaluation. (Can be hard to think of initially, but the testing is pretty accurate and reliable, so once you've thought of it you'll probably get it right).

But phenotypes vary widely. And so mis-prognosed sounds more accurate here. Probably just as bad as a missed diagnosis, so this may be semantics...
There is a very simple and clear line, actually. The moment you have to write a single line of code to specifically enable political censorship, you're complicit in it. Such as in this case, where they're not just talking about e.g. taking down links in search results when asked, but inserting new code into the entire Android software stack, or even writing new apps outright, to enable such censorship.

And yes, of course it celebrates our own values. Why should we use any other values to judge our companies? If they don't want to be subject to this, they can always split their Chinese branch away entirely, and let it be run by the locals. Then it would be a Chinese internal matter. But when software engineers in California are implementing censorship for Chinese government, they're going to be criticized by the standards that apply in California.
This is exactly the neoliberal argument against labor protections in general. People would obtain jobs with dignified pay & benefits if they could. Having an option that seems exploitative is better than having no options. Thus, imposing minimum standards on the work that can be offered is harmful. Pursue other, better mechanisms to boost and lower-bound standards of living (economic growth, negative income tax). In the meantime, don't stand in the way of mutually beneficial transactions.

This is a right-wing, Milton Friedman worldview. The left (pretty much by definition as "the left") emphatically rejects these arguments with respect to flipping burgers, running a cash register, or delivering groceries. What's special about picking up glass bottles?
Yes, there should 100% be a law. I believe the failure of even USA airlines to push back against the recent Chinese bullying over Taiwan is evidence of this.

Luckily, a lot of current and ex-intelligence members are speaking up about China being the biggest national security threat. Not just a threat to the USA, but to liberal democracies around the world. Hopefully we will find some way to push back and get our Corporations on-board with the efforts.

I firmly believe that the Chinese government is so fundamentally at odds with the values of modern liberal democracies that it's only a matter of time before it comes to a head. We may all end up regretting turning a blind eye to their BS for so long..