skysight-inc/HackerNews huggingface dataset:
I know this isn't a popular stance here but I take a number of issues with this article

> As the infamous pharma bro Martin Shkreli demonstrated, pharmaceutical companies can and will make life-saving drugs prohibitively expensive to juice their bottom line.

I agree that pharma pricing is a problem, but framing the public debate around the issue with Martin shkreli basically ensures the conversation will be based on sensationalism and appeals to emotion, rather than facts. As it stands now, the public doesn't understand pharma pricing so can't assess how likely any proposed legislation is to actually lower price. That enables the pharma lobby to work behind the scenes to make sure any govt actions sound important but are toothless. There are many pharma pricing cases that are more egregious, look at acthar gel as an example. If you want a non-biased, economics driven assessment of value based pricing for drugs look at ICER or NICE

> This means that 23andMe customers will, in effect, be charged twice for any potential “innovative new medicines” their DNA helps produce. The first time they paid for the DNA sequencing service; the second time they pay for the medicine that it helps create

This conveniently ignores the hundreds of millions of dollars per medicine that pharma companies will have to invest to get a drug to market. Pharmas r&d productivity is on a steady decline. So GSK will probably spend a ton of money developing drugs based on this data, and it's likely that they won't end up with enough meaningful new medicines to offset the cost of research. I can elaborate if people want

> Another alternative would be for 23andMe to partner with non-profit public programs, such as the National Institute of Health’s precision-medicine initiative

In which case you'd be giving your data to Google, who works with this NIH initiative to analyze data [0]. Personally I'd rather GSK have my data than Google -- at least GSKs entire business model isn't selling personal data

[0] https://verily.com/projects/precision-medicine/precision-med...
6 kinds of freedom: rotation for all 3 axes, and change in velocity along each of the 3 axes.

Cars have two kinds: steering and change in speed. Planes have about 4: pitch, yaw, roll and thrust.
Yeah, the guy who wrote the original article(that this piece responds to) had obviously never set foot in a library, because he still thinks of them as repositories of books. That's a function but it's not the main function.

When I lived in a semi-rural area as a teenager the library was one of the few places me and my geeky friends could congregate for hours. They would let us reserve meeting rooms so we could play games together. If that library hadn't been there we would have had no third place.
>IANAchemist, but this makes me wonder if there's some other chemistry out there, either undiscovered or deemed uneconomic, that offers even better performance than lithium.

There are, but of course there's tradeoffs. Lithium is the best all around cathode choice for economical reasons, but Sodium and Potassium are being explored as well. The real gains can be found in new electrolyte chemistries, though. My money is that we will be using lithium for the foreseeable future, and that advances in electrolyte chemistry will get us to the $100/kWh point.
Only if you ignore the cost of a device and service.
No. That is why 90% of all humans should have 2 children, and 10% should have 3. Or at least until large-scale space colonization becomes viable, then everyone can just go wild until the Dyson sphere fills all the way in.

A government health service should therefore not be cutting off fertility services any earlier than the live birth of anyone's second child, and should likely begin requiring additional fees for all child-related services starting with the fourth, or impose an additional tax on anyone with four or more biological children.

China's "one child" policy would probably have fared better as a "one son" policy. That equates to an average limit of two children per person, which is still below replacement fertility.
It's interesting that Rust is starting to use the same version-naming scheme that ECMAScript and Ubuntu did, being year-based. Personally I think Ubuntu's naming scheme and release schedule is the best, releasing $N times per year and naming it $YY.$N, where N is the same each year. This has a host of benefits: it's obvious how old any given version is, it's predictable when a new version will be released, it helps prevent development from stalling for any reason, especially unnecessary-rewrites and way-too-big-features, and more!
Ime, the “disrupted” products I’ve purchased were way over priced and fragile or worthless. Not just from amazon either. Oh and of course they come with daily spam.
I was a sys admin from Around 2006 to around 2014 and I used many of these things.

Our office still had (multiple) T1s, and ran on IBM as/400. When I joined in 2006, it was a startup.

Also: PCMCIA cards were definitely still around for much more than the 90s. I still have several coveted PCMCIA wifi cards that were supported by kismet.
I wasn't a 90s sysadmin, but I remember most of these. Also...

> EISA vs. MCA (vs. NuBus)

> SCSI termination and ID-conflict issues

> Apple stuff: System 7, AppleTalk, ADB

> DECnet and OSI (yes, still, in the early 90s)

> NFSv2, RFS

> Reconfiguring your kernel to add new devices

> BSD and SysV "universes" in some flavors of UNIX

> Usenet and all of the crappy software that went with it

> sendmail rewriting rules for a bazillion kinds of addresses

> KVM cables/switches with VGA and PS/2 keyboard and mouse connectors

> X Terminals and Motif

> i860, i960, 88K, MIPS, SPARC, POWER, PRISM

> Gopher, archie, veronica

> Kermit and xmodem

> Pagers

Stupid software that couldn't display indented text properly without having to add newlines. Oh wait, we still have that.
I sort of disagree. In quite a number of discussions the general 'tone' is at the very least left or center-left. In others, it does seem more libertarian right.

Generally though, I find a nice mix of viewpoints here that I don't find elsewhere in quite the same way, and I like how the unifying element seems to be a kind of geekiness, for better and worse.

It often reminds me of the discussions I'd have with various nerd-groups I've been part of. Often very eclectic, often perhaps a bit too theoretical, but almost always interesting.
2 minutes, 8 barrels: Surfer takes an epic ride into history
Yeah. Come and post it here: http://dailyprog.org/chat/
No, it's a symptom of lax policing and lax justice system.
> It would still make a lot of money without all of that, though.

Exactly. They can afford to pay taxes.

> Amazon to turn all of that down so they could make less money you are fucking kidding yourself.

Do you think the government's inabilty to effective claim taxes is in a vacuum and not driven by these large corporations? Amazon is not just innocently taking advantage of these loopholes because they happen to be there. The are actively fighting to keep them open and create more.
Is yalp better?
Ask HN: What are good resources for passive income ideas?
This is a bizarre statement. It was Trump claiming that the boy had been tortured and beaten.
It's more a personal profile than a business profile, sort of a short form biography.
> Could be that I'm from an older generation, but there was a time when people considered the idea of an institution having a long and complete list of everything you've read more than creepy, it was terrifying.

I think younger people are just in general more relaxed about privacy.
the cohesion and gatekeeping provided by a quality BDFL is hard to match with a community

There needs to be some thought leadership and gatekeeping, otherwise you get evaporative cooling, chaos, and devolution to the Least Common Denominator. All "leaderless movements" are subject to this.

https://www.lesswrong.com/posts/ZQG9cwKbct2LtmL3p/evaporativ...

The problem with BDFLs, is that when they're wrong, there is sometimes no pressure relief valve.

Sure, some communities (e.g. the Rust one) show that a sole person need not reside at the top. But that often comes with slow implementation/decision costs.

What you're describing is a republic. There is no dictator. There is no absolute ruler. However, there are democratically chosen leaders who need to make decisions that won't make everyone happy. Most importantly, there is no tyranny of the majority.
In other words, private company does the right thing only insofar as the negative publicity would hurt its bottom line. Nothing to see here.
Soundcloud as well. They have something like 175 million users but almost shutdown last year
I mostly work with firmware, which hasn't seen much innovation, especially on small devices (finally Rust is coming along). There is no way youngsters can compete with me in breadth of experience. They are still building their toolbox and design patterns, so they can learn a lot, including from me. I value their appetite.

I see myself as a child of my time, with home-grown skills typical for a time-frame. I see that time-frame fading into history much like pop-music is doing. Going by the example of rockstars, maybe my skills will still be in demand 20 years from now, because the original author has so much more depth.

In some ways I am at the peak of my skills, more focused on results and a well balanced, easy to evolve design. But grey, so not cool I suppose ;)
> It would be terribly ironic if a public institution did not abide by the law or respect your rights.

LOL. Have you been to America?
Well, with regards to software, films, music, etc, lots of people work on those. Those people need to feed their families.
And a critical difference, your gym doesn't lose actual money any time you visit. They may not want everyone to visit all the time, but it doesn't drain their bank account anytime you enter the door.
Links from the SEC website about this $5m loan:

Promissory Note: https://www.sec.gov/Archives/edgar/data/1040792/000121390018...

8-K Filing: https://www.sec.gov/Archives/edgar/data/1040792/000121390018...
Working at a big company I got a manager who was not good with people so he got management training and it helped a lot.
Can you share more details about the pipeline generating the stream? There're many factors that can increase latency.
ECMAScript was certainly a huge influence here; TC39's influence may go even farther in the future: http://smallcultfollowing.com/babysteps/blog/2018/06/20/prop...

What's funny is, it kinda goes both ways: I've recently spent a bunch of time talking to some TC39 members, and they have been talking a lot about a roadmap process that kinda looks like ours, while we've been talking about making our RFC process be a little closer to the "staged" concept that they have. Very interesting times!

Most importantly though, it had a lot of influence because they have similar stability constraints as we do; I mentioned C++ and Java in the post, but maybe should have mentioned ECMAScript as well.
Rebranding is Life
I will answer my own questions, in the context of the apps I develop and maintain:

- The Go service is hosted behind a reverse proxy (nginx or haproxy) to enable zero downtime deployments, by 1) starting the new process, 2) directing new requests to the new process, and 3) gracefully stopping the old process.

- Since we've started to use Docker, we let the Docker daemon supervise and restart our services. Before Docker, we used systemd. Before systemd was available on our system, we used supervisord.

- We thought about using SQLite for some apps. But SQLite can only have a single writer at a time, which goes against the zero downtime deployment described above (two processes can be processing requests at the same time). Thus we use PostgreSQL (and MySQL for legacy reasons) which provides online backups. Must be noted that online backups are possible with SQLite, provided the application implement it using SQLite Online Backup API [1]. Another solution, which doesn't require application cooperation, is to snapshot your disk, if your system supports this.

- We backup to rsync.net, which provides an append-only mode, through their snapshot feature [2]. An attacked cannot override or erase the snapshots of your previous backups. I think it's possible to do something similar with S3, albeit in a bit more cumbersome way, using S3 versioning and MFA deletion.

- About logs, we're still not satisfied by what we use currently.

I'd be curious to read about what others do :-)

[1] https://www.sqlite.org/backup.html

[2] https://www.rsync.net/resources/howto/snapshots.html
This makes my prostate swell. I remember all of these then there are the comments and I remember them as well. Now the internet is a phone and a server is just a slice of cloud. Ethernet is old.. Wireless is fragmented There was not any security at my job when I started my computer had its own class B address. It was part of the internet on the internet no firewall now.. my pc is behind 4 firewalls and a carrier pigeon. The other day I got an email from a guy who wanted me to pay for a video of me jerking off - I was like hey I can make my own videos plus who would want to see that anyway I bet he didnt even watch it.
Ouch. Now that MoviePass subscribers are aware of its impending demise, they're likely to use the service even more to squeeze out any remaining value before it goes kaput, further exacerbating their money woes.
First, they tried to strongarm AMC into getting a portion of ticket and concession sales [0]. When AMC said "lol no", MoviePass blocked AMC and tried to pass it off as AMC blocking MoviePass. They then lied about how much money they made AMC [1].

[0] https://deadline.com/2018/01/moviepass-lack-of-amc-theatres-...

[1] https://variety.com/2018/film/news/amc-blasts-moviepass-fals...
Over the last 20 years I often have food and / or drinks in my hands when I walk in. No 16 year old ticket taker is ever going to make a fuss about it, because they certainly don't care. It is odd how deeply rooted in everyone's mind it is that there will be a huge scene if you try and sneak in food.
> If there are (only) 100 jobs for technology X and 90 people with that skill, that's a good skill to have. If there are 10000 jobs for technology Y and 11000 developers for that technology, the ratio is not as favorable.

I'm in embedded, and I think your numbers are about right. I'd say that embedded is only 1/10th as big as "general programming" or even web programming. This means that, if you want a new job in your town, it may take 10 times as long as if you're in web programming. But it pays better, experience is more valued, and the cultures are different. Embedded doesn't have many brogrammers - it's more a world of grown-ups.
New platform that enables users to create and train their own intelligent agents
I wonder how many people saying, "We don't need libraries and librarians" don't get this. Probably all of them. Maybe if they were to shadow a librarian for a couple days, they'd be on the same page.
The Living Interplanetary Flight Experiment
Intelligent assistants will become the source of all information replacing browsers, apps, intranets, websites and the rest. But do we want to engage with endless PAs or do we want to have a persistent intelligent assistant that knows us and behaves to our preferences?
Cohen claims Trump knew in advance of 2016 Trump Tower meeting
This is a lovely story, and I enjoyed reading it.

I'm not sure the infection of haemophiliacs from blood products should be compared to Grenfell. Unlike aluminium cladding on a skyscraper, patients took factor concentrate on specific medical advice to treat bleeds that would otherwise not have stopped.

These factor concentrates required hundreds of blood transfusions to make just a small amount (they were also highly expensive, and still are today, shots can easily cost several thousands of pounds each), and they were given to treat bleeds, which were life-threatening or limb-threatening. In younger children and severe haemophiliacs they had to be given factor regularly to prevent bleeds.

The enquiry will need to look at how the pharmaceutical/product companies and health organisations dealt with incoming information, and whether they had a viable alternative at the time. There is suggestion that the UK producer of factor concentrate (BPL) was highly underfunded at the time, and unable to produce the required amount of factor concentrate to supply the country.

There is a UK public enquiry ongoing to assess whether someone or some organisation should hold responsibility for it - and I agree it is overdue.
Perhaps they are secretly working for major movie theater companies like AMC. The trick is to get more people to go back to movie theaters and then when they can no longer use their movie pass service they will still want to go to the movies.
Sending/receiving emails from it on Hotmail. As a cloud storage to my files on OneDrive. To prepare documents, tables, presentations on Office. To listen to music when there was Groove. Logging into my two Windows 10 computers. To purchase/download software to my convenience on the Store. While signing in to other websites, either using my email, or via Microsoft sign-in.

Probably just like everybody else.
Austin is a tech hub. We shouldn't paint the state in a single brush, and to say "terrible culture" is regressive and ignorant.
The way I understand your parent poster, is not, that he says don't care about environment, but don't classify Thorium the same as enriched Uranium ...
Microsoft (of all people) has a good IoT story with Azure Sphere, where they handle security for 10 years, and the device vendor handles the application. Let's hope the first commercial devices are a good proof point for this security model, so that others step up with open silicon to compete with Microsoft Linux and Microsoft silicon root of trust.
India's DataProtection Recommendation Report: A Free and Fair Digital Economy [pdf]
> replaced by something better

i'm skeptical that an instance of any given thing being replaced or "disrupted" (a terrible buzz word) necessarily implies that the new thing is "better". there tends to be a lot of factors in play.
The thing keeping me from Rust is the weaker metaprogramming relative to C++. Do you have plans to expand Rust to things like compile-time expressions, template templates, and perfect forwarding?
The American Library Association specifically discourages the behavior of your local library:

http://www.ala.org/advocacy/privacy/guidelines/library-manag...

> For example, if the LMS offers the ability to save the checkout history, this should be an opt-in feature not turned on as a default.

The policy also recommends libraries minimize collection of data in general, use HTTPS whenever possible, and maintain a warrant canary.

See also: http://www.ala.org/advocacy/privacy/FAQ
Movie theater food is expensive because theaters in the US make almost all of their profits from the food. The movies are just a vehicle to get you to buy the popcorn and soda. On big blockbuster releases, like Star Wars or Mission Impossible, the movie theater may only get 10% of the gross ticket price on opening weekend, with the remainder going to the distributor.

Overseas distributors Asia have less leverage because these markets are generally so much smaller on a dollar value basis that it's not worth the time and effort to push for 90% instead of 60% of a relatively tiny pot. In China, terms are dictated by the government. In Europe, audiences prefer more avant garde films (read: bad films which pretend to be about something) so theaters have significantly more leverage overage distributors.
Obviously, I don't know the details of 1970s/1980s plasma products, but I think it's probably fair to assume that they were screening for pathogens they knew about at the time. I think in retrospect it's easy to say that they should have taken the factors off the market sooner, but at the time it was probably a very difficult situation. Hemophilia is an incredibly dangerous condition without treatment and there was a reasonable expectation that people would die without access to clotting factors.
N4JS and TypeScript
Isn't that a good thing, then? I feel there's already way too little 'appalled and shocked' going on because we just roll over and adapt.
I don't want to argue the statistics, you probably know them better than I do. At least historically in the US AIDS:

> found its way to the United States as early as 1960, but was first noticed after doctors discovered clusters of Kaposi's sarcoma and pneumocystis pneumonia in young gay men in Los Angeles, New York City, and San Francisco in 1981.

Please don't equate being a little under-informed or less up to date with stupid thinking.

EDIT: Ah, I think I mis understood your post. Your example at the end was of poor thinking but I don't the think the parent you had replied to was making that mistake either.
They lose a little money on equipment maintenance over time, but it's nothing like going to a movie.
Investors, $10 billion more for Tony Stark or the Earth gets it!
I would too drop UDP before TCP as UDP likely won't get resent.

A great example of intuition going wrong. VoIP won't work at all during congestion even if it's not causing the congestion. If anything, dropping TCP before UDP is likely to be more helpful since TCP will back off. But now that uTP and QUIC exist, such L4 discrimination is probably just counterproductive.
Not really. This isn't San Francisco or Miami. We don't have unregulated cars here and Uber hasn't changed that at all.

We've had TLC cars for decades, aka black cars, car service cars, livery cars, etc. Taxis were never the only game in town, livery cars have been an integral part of the city's transportation network for a lot longer than Uber. I have pretty clear memories of the line outside Northside in Williamsburg every weekend night 15 years ago when I lived there.

What happened was we all got little GPS enabled devices in our pocket so instead of having to call or wait at a storefront car service spot we could arrange it all in seconds. Way better, to be sure. But in NYC Uber hasn't really changed the legal framework like it's tried to do elsewhere, it's mostly just a better way to hail and track them. And the pool thing changes the dynamics somewhat as well.

Which is great and all. But we don't have an unregulated illegal car service thing here, or to the extent we do it's unrelated to Uber. New York's TLC has regulated for-hire cars for a long long time and still do.
Sounds like sponsored content.
> Last year I was looking for a tool where one team could provide chat support to customers

Although there's the superficial similarity that they both involve "chat", customer support is actually a very different problem to solve than what Zulip (and Slack and all its other alternatives we're talking about today) is focused on. It's no surprise that Zulip wouldn't have the features you need, and it's definitely not somehow an overarching indictment of the Python ecosystem.
The first two weeks of a movie's run the theatre is only making 10% of the ticket sales. Then it slowly goes up until its cheap enough to show in a dollar theatre. If its a blockbuster the increase might not start until 4 or even 6 weeks later.
Did you RTFA before you jumped into the comments? Here, let me give you a quote.

> Just this week, a woman stopped by our desk because she needed to be taught how to open a new tab in an internet browser. She returned a few minutes later and said, “Please write ‘stomach ache’ on this piece of paper for me. I don’t know to spell it.” The man waiting behind her had no idea how to open an internet browser to begin his first job search in years. I walked him through the process and helped him get to a job site. This was a few minutes of a 40-hour workweek.

> I can’t imagine where this woman and this man would go without the library. Would Amazon really be willing to help them with all of their needs free of charge?

Information is available “almost literally for free and instantly” to people who can afford a device that connects to the internet.