skysight-inc/HackerNews huggingface dataset:
I wish I did. The hints in the literature are spread far and wide among older papers, often misinterpreted as something else. A lot of it is unpublished data from my graduate work.

First, penicillin does bind to enzymes that cross link cell wall. It's getting from there to dead cells that's the problem. First, if you knock out a set of proteins called autolysins, cultures exposed to penicillin plateau in population, but the population does not decrease. That is, there is a suicide response. Second, changing the external turgor pressure, such as by adding PEG to the medium, doesn't change the rate of death. Third, if you watch a culture under a microscope when you add penicillin, all the cells in the culture stop growing long before they die. So the unbalanced growth model can't work. I have a vague memory that the kinetics don't work out either, but it's been too many years.

More interestingly, other antibiotics, such as rifampicin and chloramphenicol, which don't target anything related to cell wall, cause bacteria to stop growing when they are added to the medium. That implies that there are active mechanisms involved, not some random fact about cell wall synthesis that happens to stop when something is inhibited. Rifampicin is supposed to inhibit protein production (and does mess up ribosome activity), but there was an interesting paper that showed that a few mRNAs were translated as normal in the presence of rifampicin, even though most were messed up. And how would inhibiting protein synthesis lead to cells exploding (which they do) by a direct, physical mechanism?

I've thought about going back and writing a review article on all this stuff, but biology is a long ways in my past at this point.
In Lituania after we implemented deposit system for cans, there was 97% return ratio in 2017. This was so unexpected that agency responsible for managing deposit system had to updated agreements with beverage producers because of this.
Refreshed Coffee Lake MacBook Pros Reportedly on Tap for Apple WWDC Next Week
I think the point TFA was making is that the 9.9% hasn’t experienced a decline in wealth in order to feed the accretion of wealth in the top 0.1%, and that such a situation creates an aristocratic attitude among that 9.9%, dulling any motivation to fix wealth inequality or economic immobility in the bottom 90%.

I believe that the term 9.9% is a slogan though.
Even just speaking out is getting dangerous, particularly for the people just entering the pipeline now as you have to provide all of your social media accounts so they can keep and eye on your speech.

It is only a matter of time before you'll sit down in a citizenship interview, and they'll have a print out of your social media posts and a bunch of questions about any that seem to criticize the government.
In the past, nobody really attacked the rich because so many Americans think they'll one day be in their shoes. In 2003, we learned that 19% of Americans think they are in the richest 1% and a further 20% expect to be someday [1]. People have slowly woken up to the fact that their math was way off and class mobility doesn't really work that way. The brief "Occupy" movement and the identification of the 1% as a species largely unlike the rest of us shined a big spotlight on a class of people who would rather not receive so much attention. This article seems to be almost deliberately engineered to downplay the 1%-vs-99% narrative that once illustrated a distinct oil-vs-water class divide in the country. How better to confuse people about who the villains are than to muddy the water by adding "slightly richer normal people" into the mix with the plutocrats and Wall Street billionaires. This almost reads as a PR piece, straight from the desk of the Koch brothers or a Wall Street managing director: "Look over there! There's a hard working father of two who owns a few laundromats and a family doctor with a vacation home! Those guys are totally relatable to you poor people, just like us billionaires!"

1: https://www.nytimes.com/2003/01/12/opinion/the-triumph-of-ho...
> Why people lose trust is another discussion, but I don’t think it’s through an entirely rational process...

I think "losing trust" is entirely a rational process. 20th century medical science suffered from single-causism [0] and frequently jumped to conclusions [1]. Institutions built treatment programs based around simplistic assumptions which were later shown to be false (cardiology/cholesterol, psychiatry/chemical-imbalance, cancer/genetics, etc), but never corrected course.

[0] https://en.wikipedia.org/wiki/Fallacy_of_the_single_cause

[1] https://en.wikipedia.org/wiki/Jumping_to_conclusions

I believe the so-called 'obesity Epidemic' is mostly a simple case of mass-poisoning with polyunsaturated oils. The experts interpreted preliminary science to decide that saturated fat was unhealthy, told us that polyunsaturated fats were safer, and the public's health has suffered ever since.

Modern medicine is great when it works, or at least helps a little. The failures of modern medicine deserve more discussion.
I'm in the middle of a project using a related microcontroller (the nRF52832). When I started, I had very little electronics/embedded experience, and now I have more! It's absolutely doable.
Nope not that one unfortunately, but thank you! :)

I vaguely recall it being a pretty long blog post that walked through various scenarios. The formatting/design of the site was pretty plain/old school.
Portability vs. extra power – What type of laptop to use when writing code
> Because developers are more akin to architects, designers, or artists than factory or construction workers, the best process is the one that defers to their judgement and trusts them to do the best work they can. When managers reach for metrics to motivate developers rather than focusing on working code, they are on unstable ground.

Exactly.
4 Critical Tests for a New Spacecraft That Will Clean Up Space Debris
> Can you imagine how terrible everything would be if everyone was middle class?

It would be a vast improvement over the status quo, where most people are either working class or underclass.

> We should focus on the very bottom, not the very top.

They aren't separate issues, they are aspects of the same issue.
Author here! If you read the article, I hope you enjoyed it.

Happy to hear any feedback or war stories from people dealing with Wordpress on AWS :D.
My cunning idea for stand-ups is to make every participant plank continuously while they're speaking, for a similar reason.
ISCA 2018 Lightning Talks
A clever manipulation piece:
It melds 1% multi-millionaires with upper-middle class to create some kind of bourgeois enemy.
In reality these 32 million people have
different lifestyles, sources of income and their networth does not indicate true wealth: they could be living in an expensive house that they bought much cheaper, but a few trips into a hospital will bankrupt them.
The whole concept of "net worth" is highly deceptive and can be manipulated into framing economic importance as function of potential wealth(if "X sold all their property" vs actual currency reserves).
Smooth-ui: styled-components based UI library
Server Project for World of Warcraft
But currently this only works in third world countries where the government lacks resources or care to combat it. Plus their is still a middleman if you don't mine the cryptocurrency yourself. I still have to pay a exchange if I cannot find someone willing to take cash/check from me. You also have the opposite effect where you need the exchange and a bank account to turn that coin I sent into usable cash.
The first wireless flying robotic insect takes off – UW News
I like the idea of a running balance. That's what I want to accomplish by enabling multible tabs/sheets. Lots of good ideas, thanks.
"Unpaid" internships are good -- they allow people who don't provide much value to learn and build their capital. People who want to work more than 40 hours should be allowed to work more than 40 hours, and should be allowed to make agreements with their employer that don't double their expense per hour at 40 hours. The minimum wage is just a price floor, and doesn't actually determine wages for more than an extremely small margin of workers, and raising it can increase unemployment among the most vulnerable populations.

Unions have the economic effect of boosting working-class wages and well-being for people in a particular group: high-skill working class people. They depress wages, increase unemployment, and reduce well-being for the most vulnerable groups, particularly minorities and those with low education. There is no broad positive effect on labor from unions; we know from the data that the benefits accrue to a certain type of worker, and it's nowhere near the lowest classes of worker. These gains are relative, and do not enlarge the pie.

(EDIT: Downvoting me doesn't make the economics literature less conclusive on this point, and there's no reason why we should expect it to be otherwise. The labor struggle is an intra-class struggle between the more-employable working-class subset and the less-employable, which is exactly what you'd predict looking at who makes up the groups.)
I suggest to anyone serious w/ Emacs to follow the master branch. I have been compiling once a week since almost a year and did not experience any breakage. My routine is fetch, see the output from "git diff HEAD..FETCH_HEAD -- etc/NEWS | less", pull --ff, compile and install. The benefit being you don't get a whole bunch of news when you update to a major version, but get there gradually; and also the master has the newer features. They keep that branch really stable.
"Those rising costs eat into every employee’s take-home pay."

"...every time health care costs rose by a dollar, an employee’s overall compensation got cut by 52 cents."

When you read things like this, you should be remembering all those articles you saw about "the widening wealth gap." This is one of the mechanisms by which wealth is extracted from what's left of the middle class and given to wealthy shareholders.

And when you read...

"The hospital and insurance company had agreed on a price and he was required to help pay it. It’s a three-party transaction in which only two of the parties know how the totals are tallied."

...you should be reminded of the now commonplace idea usually mentioned regarding Facebook et al: If you're not paying (your own medical costs, directly), you're the product. The analogy isn't quite one-to-one, but the insurer kind of sells you to the hospital. But then the hospital wants its cut too. So they work out a deal. Your illness, to either of the two companies, isn't a misfortune; it's an opportunity. They jack up the price and basically end up splitting the profit.

It needs to be regulated. But legislators beholden to those rich shareholders will fight that idea, and they'll tend to hide it behind some deep-sounding philosophical argument about free markets that they don't actually believe.
This article and law proposal was not about energy, it is all about cheap plastic, fishing equipment and tires, though I did not understand if they plan to do anything about the car tires.

You can have good environmental laws and have the person that pollutes pay and encourage recycling. I am not from US but I don't think the elections were influenced by environmental politics
This is pretty damn dangerous. False news will spread extremely fast.
Just because you own, e.g. stock doesn't mean you control the underlying means of production it represents a share of. Most people who own stock do so as part of a retirement fund. Those institutional investors, banks, managers, politicians, corporate board members, CEO's, etc. Are the ones who actually control capital. It should be emphasized that a lot of how capitalism runs these days is in the hands of huge bureaucracies that comprise people but don't quite act like people. There is a small class of people who operate at that level as individuals: these are the capitalist class.

This is an important distinction, don't you think?
The explicit invocation of the concept "zero-sum" is avoided because it's a lightning rod for criticism, where someone will inevitably chime in to point out the realization of absolute gains of utility among the losers also; specifically, that important metrics like living standards have been improving for wide swaths of the population, even those whose share of wealth declined over time.

And therein lies the disconnect: both can be true, because one of them is a tautology; and it just so happens that relative disparities in wealth among the pool of people in market for a service will cause the competition to attain some elements of an auction, and cause the poorer parties to lose out.
It's possible for us to focus both on improving conditions at the very bottom and also trying to understand how a very small percentage at the very top is siphoning so much out of our shared system.

I would argue that both issues are worth looking at.
I agree with you in every point. It reminds me the saying of some writer of old:

'All of the struggle in life comes from the fact of not being able to stay quiet in a room for a long time'.
That was just a fictional movie, man. I wouldn't read too much into that.
Agreed. In my own experience, it's much more effective when cooling a room to pull the cool air in than to try to exhaust the hot air from the entire house so that cool air will eventually trickle into the room you're trying to cool. Changing from pushing the air out to pulling it in directly was an epiphany for me when I was younger and lead to many nights of better sleep.

Even better, now that I own my own house, is a high powered fan in one window pushing the air out and another (lower-powered) fan in a different room pulling the air in with an additional window open. You can stand in front of the open window and feel the additional cool air streaming in. It's a beautiful thing.
Speak for yourself. What a dismal outlook.
There is no such thing as "fair use" (or the "three-step-test" which you refer to) in EU copyright law. There is a defined list of exceptions (almost all of which are optional for member states to implement), and "link snippets" are not one of them. Every act of copying/making available not covered under those is forbidden.

Plus, as another commenter said, this is not a copyright, but a related right – certain aspects of copyright like the requirement for the work to reflect some amount of original human creativity to enjoy protection do not apply.

You claim most links do not include snippets, but given the popularity of Facebook, Twitter & Co for sharing links, I'm not sure that's still true. Even then: Even the title of a page alone is a snippet (not specifically excluded from this planned regulation), and I bet the majority of hyperlinks on the web do include the title of the linked-to page.

As for the argument that only FB or Google would argue that small publishers will be disadvantaged by this, I refer to this lobbying organisation by independent publishers: http://mediapublishers.eu
An Introduction to Lean [0] is another nice (albeit incomplete) tutorial.

There’s a fairly active community over on Zulip [1] if you like to drop by for a chat or get some help.

[0]: https://leanprover.github.io/introduction_to_lean/

[1]: https://leanprover.zulipchat.com
A good move from the democrats will be to ageee to the border wall against the removal of these unconstitutional checkpoints.
"Every piece of the pie picked up by the 0.1 percent, in relative terms, had to come from the people below"

The economy is not a zero sum game. Even though inequality is counter-productive and undesirable, it does not mean that wealth has been "transferred" to the top 1%/10%. The poorest quantiles have become more wealthy over time as well, just at a slower rate. Here is some data on this:

https://www.advisorperspectives.com/dshort/updates/2017/09/1...
> "Our mindset affects our motivation."

It effects more than motivation. Take stress for example. Under stress - e.g., "am I fit enough?" perhaps? - the body releases cortisol. To the best of my knowledge, cortisol has been linked to weight gain. Stress effect sleep, which has system-wide implications. Etc.

The mind is the body and the body is the mind. The Western separation of the two is a myth that should be considered irrelevant at this point.
Snapchat launches its first Lens that reacts to sound
Evaluating the cost of atomic operations on modern CPU architectures [pdf]
> letting the family choose where to stick their education dollars could alleviate the vast difference in K12 education that keeps the “9.9%” in continuous power.

Could you elaborate what you mean by this? Wouldn't the best course of action to give each school the same funding based on the number of pupils, and additional funding for troubled areas in need?
I find spectrum.chat working better for communities when compared to slack. Somehow slack adds too much noise to your "work communication"

And I hate when people tag the whole channel for some silly reasons(most communities disable this option...but still)
The link goes to the text version of npr.org main page, not the article. It's clearly designed to be the worse alternative.
A voxel is no more a cube that a pixel is a square: it's a sample point. For each sample point you store material information and the value of a scalar field at this point. You can then compute normals to the sampled surface using something like the marching cubes. https://en.wikipedia.org/wiki/Marching_cubes
> Who "just has money" and doesn't control capital?

1. The vast majority of middle class wealth is locked up in (non-investment) housing. That money provides a roof and access to quality education, but in almost all cases, it's not being efficiently deployed as capital.

2. Whatever remaining money that is deployed as capital, is not done so in a way that implies control over their chosen investments. Think "majority shareholder" vs. "just another investor". That's the difference between "controlling capital" and merely having a bit of skin in the game.
We have people very rich, more than ever before. And that is just by itself something worth of careful examination. But a lot of that wealth is new. There are effective mechanisms to not being poor. More people can access to self-improvement tools than ever before.

So yes, we should focus on the lower end of the scale.
> Amsterdam has made it a policy that big events (including normal bars when the event is going on) must issue plastic cups to curb broken class everywhere. Will we have to go back to glass, or drink our beer out of paper cups?

A quick search for recyclable cups and plates returned plenty of results. And are paper cups bad for beer?
If you haven’t checked out YNAB.com, it’s my go-to for budgeting. I find it useful because it has auto-import like mint, but with flexible categories.

There’s no way I’m going to enter in every transaction (not to mention the dozen automatic subscriptions). To me, automatic import is a must. From there, it does a fantastic job of helping me plan for next month and track spending across time.

After 2 years, I have a clear sense of how much we spend on car repairs, vacation, Christmas, etc.

Anyway, I’m not affiliated with them, I just enjoy the tool.
Same here. Maybe it's hte Intel crash mentioned here: http://memolition.com/2013/03/04/a-slower-speed-of-light-mit...
You actually can't do this with slack and be compliant with their TOS (https://slack.com/terms-of-service/api):

"Functionality. You may not use the Slack API to replicate or compete with core products or services offered by Slack. You acknowledge and agree that Slack has or may in the future offer products or services that are similar to your Application, and nothing will prevent Slack from doing so;"

So any communities doing this can get their community shut down by slack at any time.
Currently using the similar `DOMImplementation.createHTMLDocument()`: https://developer.mozilla.org/en-US/docs/Web/API/DOMImplemen... : Styles and scripts of the main document doesn't apply to it. It allow to do some tricky stuffs, the main doc can retrieve values of sub documents, and we aren't forced to display it. It can act in the shadow too, allowing parallel computing. Is it the great beginning of «in browser javascript multi threading»?
Scrolling with the trackpad seems way better by default, no more mouse-wheel-scroll-amount/mouse-wheel-progressive-speed hacks !
Even the consumer is doing nicely (well, most consumers anyway).

It's just that we'd like our health care costs to be closer to the cost of delivery than to the realized value.
Why should any non-Euro companies care about the GDPR?
> Personally I do this because it's not worth it for me to recycle it on my own, but I still care about the environment and my fellow man.

> But what I'm pointing out is that it's an economically irrational decision on my part,

It's not economically irrational; as obviously the condition of “the environment and your fellow man” play into your personal utility function.
Ask HN: DIY Virtual Private Server with AWS
Hiya! I am relatively new to devops thing (I only have experience with Ansible & VPSes such as DO/Linode). I was playing with AWS and was wondering what it would take to "recreate" virtual private servers with Amazon products. I realize AWS has Lightstail offering, but I am interested what goes under the hood of such service. I would need an EC2 as a server, Route53 for DNS(?). Anything else I'm missing?
SSB is distinct from Diaspora and Mastodon in this respect. It's decentralised rather than federated (pub servers are just peers with a public address).

SSB's answer to this question is: your friends are going to store your data, because they want to read it themselves. You are going to store your friends' data, because you want to pass it on to your other friends.
Does anyone know if the concurrency support has made it into TRAMP yet? I recently switched to sshfs because I couldn't stand having TRAMP block my editor while saving remote files.
EU takes ban on plastic up a notch and forbids single-use plastics
As a not-American stories like this make the very country itself seem like the blueprint followed by the tech giants. Illegally bullying the public at large, too big to punish, let alone reign in. It's not an ideal image, is it? And most depressing is that there's not a damn thing Joe average can do about it.
BackSwap #Trojan implements new techniques to steal funds from your bank account
Stress has measurable physiological effects, e.g. cortisol levels
Site unavailable due to capacity problems. However, as others have pointed out, this (or similar) articles have been submitted and discussed many, many times.

That doesn't make it interesting or unimportant, and I respectfully suggest people should read some of them.

In particular - READ THIS:

https://news.ycombinator.com/item?id=1492894

Added in edit: This has been discussed more often than the search given by dang suggests. Here are some, with the number of comments:

https://news.ycombinator.com/item?id=16978769 (13)

https://news.ycombinator.com/item?id=16939063 (0)

https://news.ycombinator.com/item?id=14313067 (1)

https://news.ycombinator.com/item?id=11667755 (74)

https://news.ycombinator.com/item?id=11658854 (0)

https://news.ycombinator.com/item?id=9947237 (40)

https://news.ycombinator.com/item?id=9685842 (1)

https://news.ycombinator.com/item?id=7581288 (0)

https://news.ycombinator.com/item?id=5856312 (0)

https://news.ycombinator.com/item?id=5822917 (0)

https://news.ycombinator.com/item?id=4028232 (0)

https://news.ycombinator.com/item?id=2393594 (10 (mostly meta))

https://news.ycombinator.com/item?id=1647662 (2)

https://news.ycombinator.com/item?id=1492835 (127)
Imagine you had a chat, and 30 videos in the chat.

30 play buttons
30 vulume sliders
30 pause buttons
Etc

That's a lot in the DOM.

So intead you put the html5 video player components in shadowDOM and reference as needed. Only have them once then.