skysight-inc/HackerNews huggingface dataset:
Which is a good story to tell all those techno-naive who go on about the safety of modern nuclear reactors and such (it's always past designs that are at fault)...

When there's money to be made by cheapening out (on construction, safety, disposal, testing, quality of employees, etc), whether the risk to others (and sometimes even to self), some people will cheapen out.

Add human error to that, and it's better if the whole thing happens to some old-style electricity factory, and not to one whose waste needs safe storage for decades, and an accident can kill hundreds of thousands.
Multi-Lingual Speech Synthesis
Ok but I am talking about current, not historical, IP theft.
Very good analysis. I found myself thinking about this phrase:

> The mobile revolution is and has been by far the most powerful driver of centralization in the last 10-15 years.

Many of us who were active users of Skype in its earlier days (mid-2000s) might remember Skype's first attempt at a mobile client. They took all the distributed P2P goodness of the desktop client and tried to have that run on the mobile environment.

The result was sadly a smartphone app that was slow and rapidly drained your battery. For those of us with many Skype group chats open, the mobile client was basically unusable.

So Microsoft/Skype had to go back and rethink the mobile client. To your points in your reply... they made it a "thin client" with all the power in the centralized servers.

As they did that, it seemed from the outside that they determined over time that maintaining a desktop P2P source code and a mobile thin-client/server source code didn't make sense. And so ultimately the desktop P2P was abandoned and everything became client/server. (Which is the case now - Skype on your desktop is basically a wrapper for a web client.)

And so... the quest for a good mobile user experience wound up being one of the drivers for centralizing one of the original decentralized P2P apps. [1]

Good analysis!

[1] Yes, there were, I'm sure, many other contributing factors, including the issues around the supernodes that led to one of the major outages. And yes, I do realize that Skype, even its earliest form was NOT a completely-decentralized communications app. They did have a centralized mechanism for logins / authentication and also for PSTN gateways and other services.
I wonder if there is a defamation/libel type of lawsuit here.

If that would ever fly, I want to take action against mail servers that tell me my mail is "spam" when it clearly isn't and was double opted-in by their users :-D
I agree that pubic funding is an essential foundation for this industry, but disagree that the risk drops before industry gets a hold of technology. Large clinical studies are crazy expensive for many good and many bad reasons, and many of them will fail giving zero ROI. I agree that much of Pharma, (especially, but not only, some very bad actors) spend more on IP Attys and Commercial efforts than R&D, and that hurts me to watch. Academia doesn't do the research that is required to get drugs to people--who does PK and ADME studies on hundreds of animals? No one excpet industry does the detailed manufacturing process development and critical parameter work required to support approvals, especially in biologics. Yes, many drug companies need to be fixed (and some outright eliminated), but the industry does serve a purpose.
This post by the author discusses "How to Handle Monetary Values in JavaScript" and how this library relates to that issue https://frontstuff.io/how-to-handle-monetary-values-in-javas...
>Before people start criticizing nuclear power. This story is about the Hanford Site.

Anything that went wrong with the Hanford Site can go wrong with any nuclear power factory.

It's the profit and human error factors...

Not sure how many techno-naive pro nuclear factory people know that in the real world (as opposed to the fantasy world where technology is all that matters), nuclear waste is giving to MAFIA owned companies to dispose, which then save money by just dumping it in the ocean...

Not joking:

https://en.wikipedia.org/wiki/Toxic_waste_dumping_by_the_%27...

https://gizmodo.com/the-mob-is-secretly-dumping-nuclear-wast...

and that's the tip of the iceberg... Even worse in the developing world...
Will new standing up airplane seat design take off?
Oh that’s golden, thanks for sharing. :-)
Hasn’t anybody invented a cheating method that uses a separate computer which looks at the target computer screen through a camera and provides mouse and keyboard input through USB?

Something like this could probably be built with a Raspberry Pi and some image pattern-matching software. If you just wanted to record some statistics in order to give an edge in certain games, you could probably build a phone app to watch you play.
so you're saying I can simply bypass detection by having a remote proxy? Simple and cheap ($5 Digital Ocean server)
Cool, the tilt is a little odd when moving elements though.
> Do we have a word for this type of relationship between worker and company?

It is 'Welcome to world beyond circlejerk of some highest paid software workers in top 5-10 tech firms'
I'm curious. If you have 20 electron apps running, does that mean you would have 20 copies of the completely same thing wasting your disk space and RAM?

How would that work if all the application developers decided that native sucks and all should use Electron?
Distributed architecture concepts I learned when building a large payment system
I personally tend to skim sections on food as they are boring to me.
I can confirm, I downloaded the suite from Microsoft a few weeks ago.

Still comes in handy to track down some specific types of bugs.
Thanks! I tried putting links to the original articles in the extended description; some players may not show that. Or maybe I messed it up. :)
When I was in London many parts of the underground was elevated, so I guess it works for them as well.
Ton of effort for no benefit.
The big difference is not for-profit status, but the fact that Tokyo's and Hong Kong's subway operators own much of the property around the stations, and make a ton of money leasing it: http://money.cnn.com/2015/03/30/news/hong-kong-mtr-subway-pr.... Economically that makes a lot of sense. Transit infrastructure creates a positive externality: it benefits not only the rider, but the shop or office that the rider goes to. NYC's MTA can only recover from one side of the transaction: the rider. JR and MTR, as major landlords around the stations, can recover from both sides, capturing some of the positive externality.
You have to admire their ingenuity in fighting smartphone addiction by selling you another smart device.
https://www.deepcode.ai/tech/
How about a RUI (Restricted User Interface).
As shams93 said, the OLPC has tremendous industrial design, which nothing else I've ever seen matches. The plastic pieces are remarkably thick, and they all either slide or screw together. There are no sharp corners on the exterior. The textured surface is easy to hold and resists scratching and gouging. The latches are simple, durable, double as port covers, and are adorable. When closed, a series of ridges going all the way around the lid meet in to the body to keep dirt, dust, bugs, etc. from being smeared all over the screen. The screen is rubber shock-mounted. You only need one tool to disassemble the entire laptop. It has a friggin' handle. The lithium-iron phosphate batteries are much more durable than other laptop batteries [0]. And it also has the glorious sunlight-readable display.

The pi-top is only very superficially what shams93 describes.

[0] https://en.wikipedia.org/wiki/Lithium_iron_phosphate_battery
With the availability of the free Red Hat tools for building container images (buildah...) and this, it will be interesting to see what remains of Docker (Inc).
Why would anyone with sufficient money and organization to support a candidate support one who would change the rules in favor of the working masses?
> Not knowing the particular arcane rites and having neither sufficient eye of newt nor sufficient patience to get it to work, I like everyone else in the universe gave up.

One thing I feel like more people need to know: Docker container-images are really not that hard to build "manually", without using Docker. Just because Docker itself builds images by repeatedly invoking `docker run` and then snapshotting the new layers, people think that's what their build tools need to do as well. No! You just need to have the files you want, and know the config you want, and the ability to build a tar file.

Here's a look inside an average one-layer Docker image:

$ mkdir busybox_image; cd busybox_image
$ docker pull busybox:latest
$ docker save busybox:latest | tar x
$ tree
.
├── 8ac48589692a53a9b8c2d1ceaa6b402665aa7fe667ba51ccc03002300856d8c7.json
├── f4752d3dbb207ca444ab74169ca5e21c5a47085c4aba49e367315bd4ca3a91ba
│ ├── VERSION
│ ├── json
│ └── layer.tar
├── manifest.json
└── repositories

1 directory, 6 files

• `repositories` contains the tag refs that will be imported when you `docker load` this archive;

• `manifest.json` contains the declarations needed for the daemon to unpack the layers into its storage backend (just a listing of the layer.tar files, basically);

• the SHA-named config file specifies how to reconstruct a container from this archive, if you dumped it from a container (and I believe it's optional when constructing a "fresh" archive for `docker load`ing);

Each SHA-named layer directory contains:

• a `layer.tar` file, which is what you'd expect, e.g.:

-rwxr-xr-x 0 0 0 1037528 16 May 2017 bin/bash

• a `json` file, specifying (the patch of!) the container config that that layer creates. (If you're composing a docker image from scratch, you just need the one layer, so you don't have to worry about the patching semantics.)

That's pretty much it. Make a directory that looks like that, tar it up, and `docker load` will accept it and turn it into something you can `docker push` to a registry. No need to have the privileges required to run docker containers (i.e. unshare(3)) in your environment. (And `docker load` and `docker push` work fine without a working Docker execution backend, IIRC.)
I found this one: https://viewing.nyc/vintage-photograph-of-new-york-city-chil...

Yes, I'm not really advocating for a resurgence of the horse in cities, just that we get roads that can be used for more things than just cars.
Love John Gall's approach to systems. There's actually a section in Kumu's manifesto that quotes Gall's law:

A complex system designed from scratch never works
and cannot be patched up to make it work. You have
to start over with a working simple system.

https://kumu.io/manifesto#start-with-simple
they were
> Your comment doesn't make sense

Really? Does the argument that you're saving on development time by not writing a native app for your users, which gives them a subpar experience, not "make sense"?

> you don't have enough information about what we do to make any intelligent judgement

You're coming off as "you don't know me, don't judge". If this is how you feel, maybe you could share more information about what you do rather than trying to shut down the discussion?
It's not just the power used while idling. It's the power usage in general.
interesting! this link appears broken though?
https://rightmessage.com/learn/what-websites-does-rightmessa...
(via https://rightmessage.com/pricing)
Ask HN: Why Google cloud does not have DynamoDB equivalent?
How the TinyMCE team helped improve copy paste in Safari
Right now China is playing fast-follower in general with this work, but rapidly becoming more innovative.

There are quite a few Chinese companies developing their own PD 1, PD L1 and CTLA4 inhibitors (these are the first gen immunotherapy treatments), and a lot of innovation in CAR-T cell therapy (first approved products of this type were US and European, Novartis and KITE pharma). There is less regulation of cell therapy in China, so potential for some breakthroughs.

A company called Legend Biotech in China surprised the biopharma world at a major confreence last year with breakthrough work with a cell therapy targeting BCMA.

However, the amount of US and EU investmnet in immuno-oncology is still greater than in China
I thought everyone knew to not eat the food in Faerie.

Unless Mr. Valabar prepares it, of course.

Eating food is something everyone does, and is an important cultural indicator in the real world. When your book is essentially a travelogue of the hero's journey, of course you're going to describe the food. For the rest of the age, tourists are going to just show up in Mordor and order a bowl of authentic Master Samwise's coney stew. And they'll visit Lonely Mountain to order lakemen's cram, whether the locals still eat it or not. It'd be like going to Mexico and never eating a taco.
Capital can choose which jurisdiction it wants to be under much more easily than labor. This "forces" laws to be more favorable to capital than labor.
> "I think that's sort of a mis-characterization of Metta (not accusing you of ill intent, to be clear), but I'm not sure how it's taught by Goenka, maybe it was demonstrated poorly.

In my experience, it has been to try to wish good things towards all beings (the cessation of suffering that is essential to Buddhist philsophy), from those that are easy to love (family friends, etc) all the way out to those that are the most difficult to wish good things for (those that wrong you, prisoners, generally those we view as "less"), and its intent is not like a prayer, where you're trying to ask a deity to make it happen."

I believe Metta was described as "loving kindess" in the course. My characterisation of "positive thoughts" was just a simplified version of that.

If you get benefits out of Metta, that's fine, I hope you continue to do so, it just doesn't sit right with me. Desire to love and love are two different things, if you already feel it you don't need it, and if you seek it then you hold yourself back from feeling it. That's how I see it, but if you found benefit in the practice of Metta that's a good thing, and I hope you continue to find benefit from doing it.
Scientists accidentally create mutant enzyme that eats plastic bottles
Wow, crazy story! “Let’s secretly decide to put up this eyesore, spend $100k of taxpayer money on it, then when people don’t like it, try to re-educate them and convince them to like it.” Classic case of government waste and arrogance.
Learn Audio Programming with Josh Hodge
Might be worth noting that one of those third party matchmaking services (ESEA) deployed a bitcoin miner along with their client not that long ago. Caused a huge uproar.
Transparent hugepages, not explicitly configured ones, right?
Heroku is PaaS while AWS started as IaaS and these are completely different. AWS has some PaaS offerings now and is leading the way in an even lighter abstraction with FaaS/serverless. Azure and GCP definitely have unique products but AWS still has plenty of leading tech and I think it's rather misleading to say they don't have anything better. In several instances they're the best simply because there isn't even any serious competition for that niche.

The design of a webpage for companies doing 100s of billions in revenue will be rather subjective and hard to change without materially affecting that revenue so I'm not sure how valid that comparison really is, or what it has to do with "better software".

I will say that building the infrastructure to power such an efficient ecommerce empire along with AWS is not trivial and you're likely vastly underestimating the quality of their systems based on what seem to be rather surface-level observations.
A 64 bit floating point number can still represent exactly all integers smaller than 2^53 so it’s possible to use that for constructing proper rationals or doing proper exact comparisons and currency calculations within certain bounds e.g by using 1/100000 dollars as the unit you can fit any amount under 2^48.

It’s terrible to not even have proper integers but that doesn’t make the problem go away. People still have to do financial calculations in JS.
I was just questioning the ideology of the person I replied to, not making a statement on the current situation. I'm trying to get people to see that the current situation is the result of organized labor, not some natural condition we happen to find ourselves in.
There are all kinds of extra costs to consider besides labor, though what labor remains will always be a factor.

Other such factors are environmental regulations, tax breaks, shipping costs (which should always work out in favor of domestic production), cost of raw materials and energy (as you noted), access to those raw materials, knowledge, cost of land and other capex.

A high volume factory is nothing like a steel shed on concrete slabs, a factory is a building that is very much optimized for its function, and yes, it's not hard to build them elsewhere but once you have them they are hard to move.

A nice example is the semiconductor industry, which used to be a United States / Europe affair and then after a brief detour through Japan ended up mostly in Taiwan, China and South Korea.
Infertility is terrible, but I worry that technologically-assisted reproduction is a mistake that could cause far worse problems. It will remove selective pressures that keep human reproduction viable without technology. That's true for any step of it: from gametogenesis to birth. If that happens, a whole host of nasty problems erupt:

* What happens to humanity when technological civilization has a hiccup, if it can only reproduce with access to advanced technology?

* What happens to human rights when reproduction can only occur with the assent of the authority that controls the technological means of reproduction?

* etc.

Perhaps the research should be focused on diagnosing and permanently curing the underlying causes of infertility, than on trying to work around them?
Finest commuter bag for the active
True.

But you can get Mikrotik routers for about $50, which are great. Also you can choose to have a dedicated router with no wireless, and have a dumb access point dealing with the wireless part.
However, ordinary consumers won't bother.
What if that business wants to provide an "app" icon in the macOS dock, and a "program" in the windows start menu, without hiring a bunch of native developers? What would you advise for them, if not electron?
Same here, and if it wasn't bad enough other companies copy this terrible attitude.

Dinosaurs will die.
The projects emerging to build a P2P Web bring an additional non-monetary reward system to this, which is that in return for publishing good content, you get readers/viewers who are willing to help offload server costs.

The naive implementation might work by simply reseeding, say, the Wikipedia articles you've already got in your browser cache to whomever is also interested in them.

There are also UI concepts, however, to give you fine control over how much and how long you're willing to help seed. (Like [1].)

The latter might end up being the currency of low-friction microtransactions that actually stands a chance of taking off. The downsides here are that it only helps in offsetting distribution costs, but it's not good for turning a profit (i.e., funding the creator's real life living situation). It might be fruitful to create a more fungible currency on these principles, though.

1. https://twitter.com/taravancil/status/983361106461720576
I honestly try to take the L whenever I can, and do take it to the airport about 30% of the time. The trouble with the L approach is:

1. Normal rapid transit cars have no space for luggage

2. There are no express trains, so it’s not guaranteed to be faster than driving (it often is during rush hour however)

3. The airport stations are a 10 minute walk to security instead of a 1 minute walk like the car dropoff gets

4. When traveling for business I can charge in an Uber, spread out in the back seat and get some work done. On the L I’m in a cramped seat where using a laptop is hard.

So on paper I appreciate the approach New York and London (and others) have taken with a premium airport-only service.
The main thing he says, which I found fascinating, is that you can't succeed longterm in the personal assistant category without a phone, which Amazon doesn't have.
You can't count on the hypervisor being bug-free, and hardware moves from machine to machine. If compromised hardware gets into your machine, regardless of the route, the fact that your programs are running in a VM won't save you.
More or less correct, the parent comment is nonsense. There are multiple special types of cancer that can be specifically targeted now (for example CML), though few of those are chemotherapies aside some improved targeting mechanisms via antibodies. Also, prognosis accuracy has and is improving dramatically. And there are HPV vaccinations now, targetted virus treatments comming up and so much more. Immunotherapies are great but not the first and only thing in 25 years.
If you are poor, then having children before 25 birthday is likely better choice. The older you are, the more health problems happen and the more tired you are. In that situation, having children while you are still physically strong and healthy is better idea then waiting till you are over 30, tired and cant afford to pay for higher risks.

These people wont have better paying jobs when they are older. It makes little difference financially.
This easily explained:
Ketamine seems to repair some kind of cell damage, thereby increasing neural plasticity.

That is a huge asset, but long endured depressions leave many unhealthy neural circuits over the years. These have be unlearned one by one, which takes time.

Ketamine increases freedom of thought and emotion, but you still need a goal and long-term plan to precisely target and unwork all the patterns that circle back to depression.

Luckily the entrypoint away from happiness is discernable and it is bittersweet: giving up, thereby reducing stress. Which is sweet at first, but turns into hell fast.
Character Encoding in Depth
> Once we all agree that you can't do anything useful with the blockchain except buy drugs

There are plenty of legal things that are difficult to purchase with conventional reversible electronic payments. Off the top of my head:

Gambling deposits (yes, these are legal in most of the world but plagued by chargebacks from losing punters)

porn/sex toys (legal, but people don't want it showing up on their CC statements and don't trust these sites with their CC number)

"Suspicious" purchases with too much chargeback risk (eg. someone wants to buy a Macbook online with a US credit card and a Nigerian shipping address)

"Cash-like purchases" like buying a gold bar or some foreign cash online and having it shipped to your house. The margins on these types of purchases are too small to cover the credit card fees and the chargeback risk is too high because it attracts carders.

I could probably go on, but if you don't think irreversible electronic cash has any legitimate applications, you're not thinking hard enough.
T-Mobile to pay $40M over fake ring tones on rural U.S. calls
this mentality becomes a problem when its pushing real jobs that people rely on out, especially when we are talking about the founders getting immensely rich off this.
It will be cheaper in the future. Right now there are only ~4 PD-1 or PD-L1 inhibitors on the market, so it is an oligopoly. In a few years there will be a wave of competing drugs (many developed in China) and prices will fall

Also, these drugs don't just extend life a few years for a few patients. Over 50% of patients are responding to these drugs, and some of these can live 10 full years. Is $10,000 / year too much to spend so a loved one can live a healthy life? $50K / year is generally the threshold used by health economists to determine the value of a quality adjusted life year, and in this case these treatments fall below that threshold

And if you have insurance, it will cover much of that cost
Working with JSON Data in Python (Guide)
or big.js