skysight-inc/HackerNews huggingface dataset:
That's not really always the case. In the case of orphan drugs it would often be much cheaper overall to have the government fund production instead of granting new exclusive rights to out of patent medications to entities like Skhreli.

Aside from that, more than half of pharma budgets are spent on spent on marketing and patent-workaround redevelopment than on actual productive drug research (even after accounting for new discoveries that sometimes come out of workaround research).

> If we don’t want it to work this way, we need government to spend much more on research,

NIH already funds something close to half of drug research. Even more if you include basic research that has a longer time horizon.

Overall spending would go down, with the side-effect that there would be less penis pill popup ads and way less funding for the Super Bowl halftime show.
Google partners with retail giants to monetize online product searches
Aren't most actual medical research done with public funding... Or at least partial public funding?

IMO we should make drug research a public endeavor. Probably EU level.
We'll pay the costs anyways, as taxes fund pricy healthcare/drugs.

Besides the private sector is very risk adverse, that bad when you're developing drugs.
Sorry, comparison with airplanes is not fair in my opinion.

The purpose of the autopilot is to increase safety for drivers that are not attentive. However, it turns out that Tesla requires drivers to be even more attentive than regular vehicles. This is not a sign of progression.
Yes, that’s the problem with Brexit, isn’t it? No one seems to have an actual plan of how it’s supposed to be in the end.

Moving to and founding a company in a country that might expel you in a few years if you’re not a citizen seems a bit risky to me.
1) Simple is not simplistic. Sometimes subprocesses are much better than the alternatives, such as threads, as they do not share memory space and cpu scheduling.
They force the use of reasonably well defined interfaces in a way nothing else can. (If it is text you have a different self inflicted problem perhaps.)

2) Testing separate processes and coverage testing them is easier than testing and coverage of an interlinked software.

3) Using homegrown interlinked software is not a reason to skimp on devops. Nor is maintaining it cheaper than maintaining third party solutions in principle. (There are special cases.)

4) You sound sour for some reason.
I would be fine with this narrative if it were true - but it's a load of bullshit to justify plain greed.

Most of the people actually doing the research and the boring (but thorough, and necessary) test studies are paid a pittance, while the company has every incentive to do some hollywood accounting and overstate what they spend on everything. In the end it's mostly profit for execs and shareholders.
It does not have to be genetics to show correlation. Sadly research in this area is sparse but we can establish that there will be some correlation;

1) Lack of proper nutrition is linked to lower IQ. This can be fairly easily explained in that the lack of resources will lead to less development in the brain, one of the most resource intensive organs in the body.

2) Certain ethnicity types are disproportionately poor (in the US). Lack of income generally also means that nutritional situation is less ideal.

From 1 and 2 you can easily conclude there is very likely some correlation.

Does that mean we should immediately deploy eugenics? Most likely not. As you mention, high IQ "genes" could be linked to something bad. IIRC they are linked to mental conditions like depression. (Which might lead to an interesting question: if we fix poverty, will people become more miserable on average because the average IQ goes up? It seems likely total misery will go down though)

I also agree with your later statements, a lot of people tend to put all people with black skin into a single pot but there are some many fascinating different cultures and a fascinating history once you go beyond colonialism.

I think a lot of people tend to forget that diversity isn't only skin color. Diversity goes deeper than skin and body.
You might like the anime film Time of Eve. It's been described as the best Three Laws work that isn't Asimov or an adaptation.
Rampage is laughably dumb, i wish it could be available online
> Apple is a bit special though, since their hardware and software go together.

You mean that there are no applications programs written by other than Apple for Mac computers? So, there's no Apple version of Autocad, Adobe Acrobat, Distiller, or Premiere, no version of D. Knuth's TeX, no LaTeX, no way to compile and run LINPACK, no SPSS or SAS? Or for each of these, have to get a 64 bit version? Maybe a 64 bit version doesn't exist? Maybe the user already has licenses for 32 bit versions and wants to continue using that software?

I don't know anything about Apple; I've been on mainframes, super-minis, DOS, OS/2, and Windows. So, I'm asking, trying to understand. Some of my most valued software is old, for 32 bit Windows, and I wouldn't want to be without it. So, I'd guess that no longer running 32 bit software would disappoint a lot of long time Apple customers, but I don't know anything about Apple.
I think docker is going to become an example of this.
They are saying that Tesla drivers are not super humans, and only average every day, garden variety human beings...

The funny thing is that it is the same people who are arguing for self driving tech by saying that "Humans will do dumb shit", is the same ones who justify Tesla by saying "Humans should not do stupid things (like ignoring the cars warning)"..
As someone that works in biotech and has worked in pharma ocassionally, we need to charge more.

I know this sounds terrible, but I make 1/5 of what an average engineer does at FaceBook and I live in the same city.

So get fucked and die or pay.
Some computer scientists are trying. Hassabis for one.
That same AI drove me away. I subscribe to 3 hobby-related groups and because virtually all of my family and friends no longer post anything on Facebook, I only ever see content related to that hobby.
32-bit app compatibility with macOS High Sierra 10.13.4
> That requirement is as sensible as saying that vancouver should outlaw residents from vacationing outside vancouver to ensure there are no vacant properties. Its not the goal to maximize each minute within a housing unit, thats not something you want to focus on.

You do want people living in their homes for the vast majority of the time. You want them living there, hopefully being part of the community, getting invested in their lives there. The original argument is very sensible.

> There is no need to look at such thing. In this case you are trying to look at each potential dwelling unit as an abstract unit and each resident as a unit, but they have their own differences and imperfections. Looking at such a metric will push you to think policies like moving long term residents to hotels!

This is only sort of okay. No reasonable person who cares about housing would push to move long term residents to hotels. This is just a terrible premise to put forward.

> I can tell you people travel a lot more because of airbnb, and that there are way more cities that don't care about airbnb at all because it doesnt affect their housing market significantly.

Do they really? Like whom? AirBnB isn't particularly expensive, and all-in costs are more often than not more expensive than hotels. I don't know _anyone_ who says they travel more because of AirBnb.
Funerals can be expensive...
Are you kidding? I would jump at the chance to implement New Zealand's system in the US and throw ours in the trash where it belongs.
What we’ve learned about selling high-tech to mainstream customers
Over half of UK internet users at risk from router security issues
> This is why, as the head of Google's self driving effort once said, partial self driving "assistance" is inherently unsafe.

Sorry, but this is the exact wrong conclusion to make from the available data. Partially automated cars have been driven by average people on the public roads since 2006, when the Mercedes S class got active steering and ACC. There is no data that says that these systems, which are available on cars as affordable as e.g. a VW Polo, lead to more crashes. In fact the only data I have seen suggests that they reduce crashes and driver fatigue significantly.

The issue that such a feature is systematically crashing and even killing its users is very specific to Tesla. Tesla's system has had a tendency to run into stationary objects for as long as it has been available to the public. Teslas have a significantly higher rate of causing insurance claims. There are countless videos showing it happening, the two (possibly three) fatalities so far are just the tip of the iceberg. Tesla blamed MobilEye (their previous supplier of camera-based object detection hardware), but it seems fairly evident that Tesla's system has the exact same systemic issue even with their new in-house object detection software.

My opinion as an engineer working on this exact kind of system for one of Tesla's competitors is that Tesla's system just isn't robust enough to be allowed to be used like all other manufacturer's autosteer/ACC systems. IMO that's because their basic approach (doing simple line-following on the lane markings) is super naive. A much more intricate approach needed. One that does some level of reasoning on what is a driving surface and what isn't. This has been known in the automotive industry for over a decade. Sorry to be so absolute, but frankly it's just unnacceptable that Tesla is gambling their customer's lives on such a ridiculously half-baked implementation.

> Lane following assistance without good automatic braking kills.

Correct. It also kills when it lies to the driver about how confident it is in a given situation. Many of the crashes, instances of cars veering off into oncoming lanes etc. we have seen would not have happened, if Tesla would fall back to the driver in sketchy situations. However what it does do instead is not even notfy the driver that the system is hanging on by the barest of threads. This works out fine quite often and makes it seem like the car can detect the lanes successfully even in sketchy situations. Yet once the system (and the driver) runs out of luck, there is absolutely no chance to rectify the situation.
Only for the patient and only in the immediate term. But if you could increase your wealth by more than the cost of the cure by living longer, then you could say dying is more expensive. And the same for society, if your future contributions (taxes and others) are worth more than the cost of the cure.
Calories that not abosorbed are calories-through, not calories -in.
I thought you were speaking about some Linux specific APIs.
If a company as big as Boing really believed into the technology, wouldn't they have invested more?

How? I suspect (but cannot prove) that the company doesn't need any more money right now. They've got 160 employees and their research programme is (I understand, but cannot prove) fully funded.

stock value symbiosis

Which stock value is that?
AirPlay 2 is supposed to provide this ability.
That’s a better case for typical style transfer than this.
The same issue always occurs where you have static constructors that are not constant.

That's why it gives you a compiler warning, and why your IDE marks it in yellow.

The same issue occurs in any language with static constructors, including Java.
The drug costing more does not equate to you earning more, it means the company you work for earns more.

Which might or might not translate to you earning more money, but the people in the chain 'above' you will each want a slightly larger share as well. Plus why should they pay _you_ more when they can find people willing to work for the industry average?
Driving a Tesla in the "auto-pilot" is like taking my 16yo kid for a teaching lesson while I am in the passenger seat, sweating and sometimes hoping for the best when she makes a mistake that could be fatal. And as a software engineer, I have more faith in my daughter than Tesla's software.
I like the idea, but I must admit that (with my background of a mathematics researcher, but almost completely ignorant of quantum physics and quantum physicists' notations) it is rather difficult to understand. In particular the bra-ket notation (which to me is already difficult due to its breaking the obvious way to match parentheses, but this might just require some time) seems to be used inconsistently across the paper (I believe that different authors wrote about the different algorithms, and the variations are rather evident and unhelpful). There are some formulas of which I cannot make any sense (last example I found: in the definition of QFT inside Shor's algorithm, the k inside the ket ranges from 0 to N-1, while according to the introduction it should range on all the combinations of a certain number of qubits).

Also, some authors seem to take for granted some concepts (such as the properties of the quantum gates) that are not explained anywhere and not obvious to me.

Still, an interesting read.
But this inquiry didn't seem to care about whether the specifics of computer hardware map onto biology or vice versa to any interesting degree. They care about whether the computer is a dynamic system of such complexity that it's resistant to current causal analysis.
This. The UTF-8 decoding is broken, and I didn't look at anything beyond that, resulting in a heap buffer overflow with untrusted input.

And here is a summary of the warnings I get when compiling with "-Weverything":

26 [-Wcast-align]
20 [-Wcast-qual]
6 [-Wconditional-uninitialized]
24 [-Wdollar-in-identifier-extension]
172 [-Wold-style-cast]
2 [-Wshorten-64-to-32]
3 [-Wsign-compare]
25 [-Wsign-conversion]
3 [-Wunused-parameter]
72 [-Wzero-as-null-pointer-constant]

Please don't use this code.
Selenium IDE 3.0.1 released
Er, that's a way in which the microchip problem is easier, not harder
>Humans can only look in one direction..

Last time I checked, I could move my eyes, up and down, side to side. I could also rotate my whole head, that also up and down and side to side.

And I am a human being.
US approves artificial intelligence device for diabetic eye problems
would you care to elaborate on what parts of Discover that are powered by AI?

In all honesty, I think the lines are severely blurred at this point.
And what's your experience vs xamarin ?
Probably better to ask how many drugs are developed without public funding.

Usually, the private sector finds public funds for the risky parts.. or starts off from discoveries made with public funds in a University.
I posted on https://www.producthunt.com/posts/facebook-data-analyzer. Would be really grateful if you could upvote!
And it'll be fun when stuff like this http://time.com/4793331/instagram-social-media-mental-health... starts getting more mainstream traction...
> That is not an accident. It follows directly from Musk's decision to cut costs by trying to do the job with inadequate sensors and processing.

Any references to support that statement?

First, how do you know it was Musk's decision? And second, when you imply that by using lower cost sensors (cameras), Tesla is cutting costs, how do you support that?

Their lower cost of sensors might be offset by having to spend more on software development for image processing, for example. When summed up, the overall cost per car may increase significantly.

At least to me, it is not clear at all whether Tesla's self-driving technology cost per car is less or more than it is e.g. for cars which use lidar sensors.
If I was driving a car like that I think I'd feel safer if there was a "confidence meter" available, I have no idea about how these auto-drive systems work but I'm guessing there's some metric for how confident the car is that it's going in the correct direction. Exposing that information as a basic percentage meter on the dash somewhere would make me feel more confident about using the auto-drive.

I can understand why this wouldn't happen from a business perspective, and it's also presumably not as simple to implement as I'm implying, but I can't think of a better way to get around the uncertainty of whether the car's operating in an expected way or not.
I agree with Cenk. There were actually quite few "bad" questions, even those that for some have "obvious" answers.

The bigger issue is that in some cases the questions were a bit too general, which allowed Zuckerberg to respond to them while actually dodging giving the right answer.

Like for instance, the senator Ana thinks embarrassed himself the most, was trying to figure out just how much Facebook allows users to delete the data the company has collected on them or data the users have given to third-party developers. But Zuckerberg is pretending to be dumb and not fully understand the question and says "but Senator, we already allow you to delete the data!"

But we know Zuckerberg is being misleading there. Facebook doesn't allow you to delete all the data they have on you. They allow you delete the data you've posted online yourself at most (and maybe some other interactions on the platform, but it definitely doesn't include data gotten from cookie tracking and whatnot).

The Senate questions were actually pretty good. It's the House questions that I found much more boring/uninteresting and repetitive. I think the biggest mistake the House members made and also a bit the senators was to confuse advertisers with third-party developers.

So they kept asking questions about Facebook "giving/selling data to advertisers" when Facebook is mostly doing that with third-party developers, and they are the ones actually getting your data. Also, Facebook has been sharing your data with data brokers, but almost nobody asked the right questions about that.

And when someone did, Zuckerberg again dodged easily saying "we've ended those partnerships" but there was no follow-up asking what happened to all the data they've given them for years, which was very disappointing to see.
At what point is an attentive driver expected to notice that autopilot has silently failed? The video linked at the top of the thread has a <1 second interval between the car failing to follow its lane, and plowing into a concrete barrier.

This is actually harder to do then just driving the car.
I'm pretty sure that even if that thing costs a million, your salary will not increase.
Seleium IDE now works with Firefox Quantum and has been published to the Mozilla Addons store
What Federal funding are you referring to?
Yes, the wheel turns, and the driver can over-ride/take over from the Autopilot at any time by just turning, or resisting the auto-pilot's turning of the wheel.
There's nothing "late stage" about it, it's been going on forever. Literal wars have been fueled just to sell more product.
The moment you take your phone off flight mode, the plane will nose dive steeply until all meet their doom.

Unless of course you put flight mode back on again.
Not all Oklahoma laws and regulations serve a valid purpose
The problem is that you don't know what the car is going to do. E.g. if you see a barrier you would mentally prepare to steer. But if you trust the car you don't prepare and then suddenly have to take over at the last moment when you realize the car is doing something wrong.

That means the autopilot doesn't help at all since you would have to basically drive manually all the time anyway.
I personally think the impressive part of cozmo comes from interaction and design, rather than AI.
> Actual usage is really the only way anyone will know if the models are trained appropriately to handle most/all situations they will encounter in the real world.

Because testing stuff before throwing it on the market isn't a thing anymore?
To the author - I understand that you're excited about this. That's awesome, and I'm sorry if I poked too much fun at your code in some other comments. Please take this as a learning experience and please keep trying to create new things - but please also label your code as not production ready when it isn't production ready.

Some high level things you may want to learn: the "mutable" keyword (to stop having to cast "this", "const_cast" (when you actually do need to cast "this"), "enum" (so that you don't have to use "Bool" in the way you do), smart pointers (reference counting is hard, you should let the compiler take care of it for you in this case), "delete []" (make sure to always pair it with "new []").
> Threats aren't exciting because, there is not threat

Thats because it's not primarily about the action but about the technological, social and societal issues and conflicts. For me at least.
To be able to provide public funding, you also need to have public money. So it still seems valid to compare productivity of countries (in terms of cures invented).
CakePHP Get IP Address?
is this something like this XKCD? :)

https://xkcd.com/1588/
Fine - so that is one. Any more numbers?
> That's not really always the case. In the case of orphan drugs it would often be much cheaper overall to have the government fund production instead of granting new exclusive rights to out of patent medications to entities like Skhreli.

You're conflating two things. Orphan drugs are drugs that aren't profitable to produce, for whatever reason. Shkreli did something a bit different and more complex:

https://en.wikipedia.org/wiki/Pyrimethamine#Availability_and...

> NIH already funds something close to half of drug research. Even more if you include basic research that has a longer time horizon.

The NIH spends 32[1] billion per year, whereas the global spending is ~160[2] billion. So around 20%. That's a lot, but not nearly half.

> Overall spending would go down, with the side-effect that there would be less penis pill popup ads and way less funding for the Super Bowl halftime show.

That's a fairly simplistic interpretation of the world. In general, companies tend to be much more efficient at spending their money than governments. We should expect a substantially higher level of productivity per dollar from businesses than we get from government spending.

There's definitely a reasonable debate to be had about public funding models, but it ought to be properly contextualized by the realities.

[1] - https://www.nih.gov/grants-funding

[2] - https://www.statista.com/statistics/309466/global-r-and-d-ex...

The global R&D spend is
Farmland Birds in France Are in Steep Decline
It seems unlikely that there are no empty properties what so ever in a big city like Vancouver, surely there must be some.

Do you have any sort of data to back up your claim that there are no empty properties?
RoboVM.
Hypothetically, it might say that all Tesla cars being built today have both the hardware and software to make full self-driving possible.

It doesn’t; what it does say is perfectly clear to me.
> Aside from that, more than half of pharma budgets are spent on spent on marketing and patent-workaround redevelopment than on actual productive drug research (even after accounting for new discoveries that sometimes come out of workaround research).

Do you have sources for this? It could really change my point of view on the issue but I need something more...
Microsoft's Skype Real Time Language Translation (2014)

https://www.youtube.com/watch?v=RuAp92wW9bg
The thing is, there are a lot of stationary objects alongside/near major highways (signs, bridge supports, barriers, etc.). The radar systems are not 100% accurate about whether a particular stationary object is in the lane. In nearly all cases, stationary objects are not in your lane (if they were, the previous driver in the lane would have hit them). Thus the radars are tuned to detect non-stationary objects, as those are slowing cars, merging cars, etc. all of which are commonly in one's lane, and which require action from the Autopilot.