skysight-inc/HackerNews huggingface dataset:
1) So do placibos

2) They're common while tapering too.

3) Agreed

4) Possibly true. What's unpolite about mentioning this?

5) Wrong analogy; depression only increases would be analogous to increased cholesterol. What are statin drug side effects when quitting, from the drug.

6) The mechanism of action isn't even fully understand. You're absolutely wrong to claim "we would have seen them (long-term side effects)". Isn't there an article on ceiliac disease and how long it took to pin down on HN's front page now?

7) You mentioned in #6 we should already know.

If I had a rant, about overly-confident individuals posting on forums. While I've no reason to believe you were intentionally dishonest, the over confident, "factual" sounding, behavior has the same basis as disinformation activists.

Experience? Was on antidepressants. Had a horrible side effects unrelated to depression coming off them. Safe my ass.
This article is selectively quoting parts of a piece in The Economist [1] in a way that's incredibly misleading. It seems like the author is trying to spin the facts in a way that is not supported by the original source.

The Economist talks about mining bitcoin in Venezuela being profitable due to government-subsidized electricity.

> Venezuela is the cheapest place to mine bitcoin in the world. Miners are arbitraging, buying an underpriced commodity (electricity) and converting it to bitcoin for a profit.

On the other hand, this article tries to claim that large numbers of Venezuelans are using Bitcoin as a currency, saying things like:

> Eventually, the people of Venezuela landed on bitcoin, the only currency that is censorship-free and digital, which cannot be confiscated or restricted by the Venezuelan government.

This claim is unsupported by the Economist article. It also conveniently omits the conclusion of the Economist article:

> President Nicolás Maduro does not like bitcoin miners, and the government’s ownership of the electrical grid enables it to locate, and crack down on, those using the unusually high amounts of electricity that bitcoin mining requires. There are no laws regarding cryptocurrencies, so targets have been arrested on spurious charges such as energy theft. Mining equipment has been seized by officials, some of which was then used for their own gain. While bitcoin can protect from the tyranny of governments printing money, other kinds of tyranny remain unchecked.

[1] https://www.economist.com/blogs/economist-explains/2018/04/e...
I used to get imipramine, which was replaced with venlafaxine. The latter was shit, but of course no one could prescribe imipramine just because I wanted it (also probably because it went generic and it was too cheap to prescribe). Fuck them all, bunch of crooks.
I've probably abused it too much but its shocking how much it load it can bare.

* Ebook Server

* Ad Block via DNS

* Router (needed me to get an expensive wifi receiver) over VPN

* Mini build system to publish my blog

* Auto-backs up my NAS box to S3 / Glacier (and then test-restore the latest backup) every month

* Auto-emails me based on a wide variety cron-jobs that check the weather, stock market, rss feeds, etc

* Grabs by RSS feeds and bookmarks

* Offline cache for some stuff

* Downloads videos for later reference

* Automatically texts me when I've not written anything worthwhile (in code or blog) for a while

[edit]

* Using it to teach python / basic programming
This is exactly the case.

Psychedelics used in the right setting are actually proving to be wildly successful in treating depression, PTSD and others.

Maps.org has MDMA in phase 3 clinical trials.
I seriously doubt the author has spoken to a single Venezuelan about Bitcoin. A couple realities:

- dozens of miners have gone to prison for exploiting power subsidies. Mining now requires pooling electricity from neighbors to hide high-usage households

- vast majority of Venezuelans don't even know about Bitcoin, remains a niche topic, not a useful currency at the moment

- unlike Bitcoin, the Bolivar has a military and police force behind it, they will squash competing currencies that begin gaining momentum
You nailed the point, but these downvotes are suspicious regardless of that. I receive downvotes often, so I know the pattern. Two my comments are downvoted in short burst: 4 downvotes at once. This is why I asking to check downvoters for vote-ring or something like that.
At Apple? Campus security would probably have a discussion with you if you stayed on their premises for too long without a badge.
"(all TLDs are 2 or 3 characters, apparently)"

Which is odd, since there are some very, very old TLDs that are "long" ... I am thinking of .bitnet, .uucp and even the old .ussr[1] ...

[1] "Initially, before two-letter ccTLDs became standard, the Soviet Union was to receive a .ussr domain." (https://en.wikipedia.org/wiki/.su)
Rather than trying to bespoke solve things. Reduce the problem into a common interface.
So why not call it RPC?
Quite symbolic that my original comment is flagged and now invisible. That's exactly how truth is being suppressed in the US. Original comment was: This shouldn't come as a surprise to anyone. Modern medicine is not in the business of curing diseases. It's all about disease and symptom management.
On benefits because of LPG subsidy: the benefits are vastly inflated in the government press figures. The real numbers are around 200-300cr if you remove the existing initiatives and inactive connections[0]. If you factor in the cost, this is not worth it.

>the real difference is felt by that poor man who is finally getting what was due to him.

The poor man was screwed by the middleman earlier (aadhaar does not solve quantity fraud - your fingerprint matching does not guarantee that the shopkeeper gives you exactly 5kg of your quota of ration) and continues to be screwed by the middleman. At the same time, the DBT scheme has seen intense opposition from people on the ground.

>According to a press note issued by the campaign, Rai did not deny the results of the survey that said 97% of people are unhappy with the new system.

Rai here is Jharkhand’s food minister Saryu Rai

Daily Wage laborers have been most impacted by DBT[1] in their ability to get benefits timely because of exclusion issues with aadhaar, but the government keeps marking these figures off as "savings".

[0]: https://medium.com/karana/lpg-savings-due-to-aadhaar-is-only...

[1]: https://thewire.in/rights/jharkhand-nagri-ration-pds-direct-...
ok, found it.

"TIL of "Zero", a soccer stadium in Brazil in which the midfield line is aligned with the Equator - zero latitude, which makes each team defending one hemisphere." https://www.reddit.com/r/todayilearned/comments/8airs6/til_o...
The original source referenced in The Economist :
https://www.economist.com/blogs/economist-explains/2018/04/e...
Discontinuation effects are listed on the patient information leaflet for venlafaxine. Patients, at least in the UK, are always given this leaflet with every packet of medication.

https://www.medicines.org.uk/emc/product/4487/pil

> If you stop taking venlafaxine suddenly you may get withdrawal reactions (see section 3)

[...]

> Do not stop taking your treatment or reduce the dose without the advice of your doctor even if you feel better. If your doctor thinks that you no longer need Venlafaxine tablets, he/she may ask you to reduce your dose slowly, before stopping treatment altogether. Side effects are known to occur when people stop using Venlafaxine tablets, especially when Venlafaxine tablets is stopped suddenly or the dose is reduced too quickly. Some patients may experience symptoms such as tiredness, dizziness, light-headedness, headache, sleeplessness, nightmares, dry mouth, loss of appetite, nausea, diarrhoea, nervousness, agitation, confusion, ringing in the ears, tingling or rarely, electric shock sensations, weakness, sweating, seizures or flu-like symptoms. Your doctor will advise you on how you should gradually discontinue Venlafaxine tablets treatment. If you experience any of these or other symptoms that are troublesome, ask your doctor for further advice.
The case in an email address does matter. Look it up.
> Keep in mind that SSRIs appear to do little more than active placebo in the vast majority of cases

This isn't true. We know that antidepressants are significantly more effective than placaebo for most people. https://www.ncbi.nlm.nih.gov/pubmed/29477251

We are now gathering evidence about which antidepressants are most effective and least likely to cause people to stop using them: https://discover.dc.nihr.ac.uk/content/signal-00580/the-most...
dna replication is very map-ish. then they can fold back to a reduced state
If you go back to the US of the 1910-1930s, most people lived in near poverty, ... until a socialist plan of wealth redistribution called new deal was implemented.

Actually the USA in 1910 was the richest society the planet had ever seen. This was why half of Europe was busy trying to move there, to start at the bottom. (It was poor by today's standards, of course.) It's a lie to claim they got rich "because of socialist policies".

The depression was a brief dip in the growth of the income of the average guy, over let's say 1870-1970. Things went backwards by the equivalent of about 15 years or progress (on average! it was rough for some). The effect of the new deal on ending this, or perhaps prolonging it, is a confusing issue. Certainly it paid some people's wages, and hit some rich people hard (and had non-economic implications too), but my understanding is that there's a serious argument that, without such action, the depression might have been sharper & shorter, like the 19th C ones.
https://air.bar/mac
I generally agree, but I still found it useful simply for up/down scrolling while reading an ebook or news articles while on the couch. Basically when I don't need to use the keyboard at all for an extended period of time.

I can hold the laptop differently in that case, using it more like a tablet. I did this often enough where I was happy I got a touchscreen...
>> The large truck uses artificial intelligence, Internet-enabled sensors, machine learning and advanced robotics

Oh to be playing buzzword bingo during this boardroom presentation!

It's unclear how "real" this solution is, but this type of invention can be very profitable. When I was a kid we had a family friend who built animal control fences along major highways in Western Canada. That means lots of rocky ground and traditional fence post pounders shatter a lot of posts; he said bids accounted for 10-15% waste where the post would hit a pumpkin-sized rock and get pounded into firewood. His innovation applied constant hydraulic pressure and vibrated the post instead of pounding it. Rocks would be pushed to the side and bubble up above ground, leading to breakage of < 1%.

Another example is daylighting services that excavate in complex areas, like around electric and gas pipelines. Rather than the super dangerous and disruptive act of digging it up with heavy equipment they use high-power water to dislodge the material and vacuum up the slurry. They can go into a busy city center, work around all sorts of infrastructure and barely disrupt regular activities.

I'm not sure how much ML, internet-enabled anything or blockchain is required but these solutions are no less cool as far as I'm concerned.
Apache Spark can do this too, similar to the Apache Drill comment. This thread is starting to feel like Stack Overflow a bit.
It's bad enough that the ultracrepidarians post in these threads. I dread to think what would happen if they ran start-ups.
I'm from India too. While I don't support the Aadhaar program in it's present form, just so that we understand the arguments from the other side:

India has a lot of problems but most of them stem from two causes:

1. Corruption
2. Inequality

In positions of power, corruption is universal. I have yet to meet a person in Bangalore who has been able to purchase property without paying a bribe. Too many of our government 'servants' are sociopaths. It's a generally accepted fact (with no citation needed) that a non-insignificant portion of government spending on social programs and infrastructure is going un-tracked into private pockets.

Secondly, inequality. A lot of people get away with things in politics. Robert Vadra gets through security checks though he's not a diplomat, Modiji (allegedly) gets degrees without going to college and Jayalalitha from my own state had people falling not only at her feet but touching the tires of her car.

Aadhaar is the 'leveler' that shines light on the financial activities of all these people.

1. Aadhaar is linked to biometrics = aadhaar is linked to a real person

2. You can't live / work in India without Aadhaar = Government employees and people with influence are not exempt.

3. You can't handle money or avail social benefits from the government in India without linking Aadhaar to it = Illegal money can be tracked.

This could solve a lot of problems.

Of-course there are problems with this apart from the well publicized privacy issues. You can apparently purchase fake Aadhaar cards for a few hundred rupees. It's been reported that more than one person has bought an Aadhaar card for a pet and if it's that simple to beat the system then all the good intentions fall flat.
Canadian Town Reels After Bus Crash Kills Beloved Hockey Players
MDMA is in phase 3 clinical trials for PTSD and something like 65-85% of participants don't show any signs of having it 12 months after treatment.

Maps.org
Yes, that is correct. In theory, a single incorrect unsafe block can have effects on every other part of the program.

Of course the idea is that you limit the unsafe stuff to small areas of the code so you can really think through those parts to make sure they do what you think they should do. Another thing that's nice about containing the unsafe code to small blocks is that you start each unsafe block from a state of the program with all the guarantees from the surrounding safe code, which makes it easier to recognize what could go wrong in the unsafe code.
"Something like this" - you mean a touchscreen? There are plenty of laptops with them on the market.
You probably know whether you're paying for Netflix though.
On a moderate but above average salary in Spain. If I get some inheritance when my parents die and have my own apartment paid off, then I could be in the top 1% in 20 years time. I am by no means rich by western standards, just a bit above average. Do you suggest we hang all pensioners who have paid of their properties and earned a reasonable wage throughout their lives in Western Europe?

Jordan Peterson seems correct for a certain percentage of people when he says 'Middle Class Socialists don't like the poor but they hate the rich'. Your comment comes across as backing that up.
The attitudes of Germans towards Americans, and vice versa, were completely transformed from fear and distrust to friendship by the Berlin Airlift.

The hedge-hopping was risky but accepted because that's how you evade enemy radar and anti-aircraft batteries. They had to ensure the Soviets knew they couldn't win an air attack on the west.
I agree with (some of) your original post in that Venezuela is an ailing nation at best, but at the same time, it shouldn't take too much imagination to see that if you can convert cheap (in Bolivars) electricity into currency that is accepted at a much better exchange rate outside of the country that one can have supplies shipped in.

Moreover, we know that in currency crises, black and gray markets spring up like wildfire, so it takes even less imagination to picture a proprietor starting to prefer crypto currencies in exchange for tangible goods vs. the already bad -- and more importantly, still declining local currency.

Despite the volatility of crypto currencies, and the fact that they've been on a hard slide lately, it's still a better depreciation than hanging on to Bolivars.
"The large truck uses artificial intelligence, Internet-enabled sensors, machine learning and advanced robotics".

It certainly is describing a very "tick all the buzzword checkboxes" machine. "The sensors are Internet-enabled? Such modern! (/doge)"
IIRC Netflix accounts stay logged in over password changes, but there would be no way to change the email back.

I really don't see how this could be an effective scam.
From what I've heard, the consumer end gear supposed to use phased arrays "about the size of a pizza box" and cost in the range of $100-$300.
Plenty like under 0,1% ? That doesn’t make it less of a target.
Yes, the attempt to reduce symptoms is admirable when a cure is not available.

Fortunately Psychedelic medicines are coming online that can allow for actual healing of the underlying patterns. They saved my life for certain.
How exactly is the cost really low?

The study you linked doesn't scientifically prove antidepressants help.

Exactly, what undue bias against antidepressants have you found?
How does your currency fluctuation affect people on a daily basis: fuel, rent, income, groceries, etc...
Why Americans are avoiding the doctor: high costs
If you liked this story, https://www.folklore.org/ is a treasure trove of more Apple folklore.
USD is most popular
What about prostitutes?
Pretty sure you mean "still scared by the quality." At least, the people in my family sure have more issues than they should.
Netflix offers SMS password resets.
New study suggests early humans mated with the Denisovans in 2 separate waves
The original article was to have a voice-over that explained such things.
> That said, it's important to note that this is unlikely to help much with most OLTP queries just looking up information quickly via indexed data.

It'll definitely not help for that, at least for now. There's not yet any caching around JITed programs, which makes it completely unsuitable for OLTP. With caching (which requires some larger changes to postgres, which is why this won't be in v11), it's possible to observe some moderate gains.

> I wonder if AWS will incorporate these improvements into Redshift, which is Postgres forked for OLAP use cases where this is far more prevalent. In the past, they haven't done a great job at this (ran into a float bug fixed upstream 5+ years ago), but this may be a big enough value proposition to justify the effort.

I can't imagine them doing that. This uses a whole rewritten expression evaluation engine (introduced in v10), and a large number of infrastructure changes all over the executor (reimplementation of targetlist set returning functions, projection, ...). Not impossible, but certainly not something lightly done.
I think bankruptcy will be next. Not sarcasm.
I have seen a few discussions on the change my view subreddit and its better then average, but I would still say its a fair bit lower than the standard of discussion here (at least for the subjects I saw).
Congruent with this: https://www.vox.com/policy-and-politics/2017/10/16/16357790/...

I wrote about this further here: http://seliger.com/2018/03/27/preventive-care-doesnt-save-mo... but I find it baffling that mandated price transparency isn't on anyone's political agenda. The political right should like transparent pricing because that's a basic component of free markets; the political left should like it because it will help people, especially people who might otherwise not be able to afford care, pay less through comparison pricing.
I remember we were told that all critical facilities in the border areas were spaced wider than a 20 kilotonne blast radius. That really brought home the nature of the threat.
To be fair, it's not like Apple's updated all their apps for iPhone X either.
SSRIs help even if the causes are psycho-social. Obviosuly the person also needs the other stuff too in those cases - fixing the situation; some talking therapy - but meds aren't useless.

No-one credible talks about a chemical imbalance anymore.
It was a Nokia Lumia 630. I think it was on Windows 8.1.
What? It's literally in the title of RFC 5233. "Sieve Email Filtering: Subaddress Extension". The introduction starts with a sentence that defines subaddressing. It has half a dozen references to using + as the separator between the username and the "detail".
> SSRIs are not psychoactive, and better studied.

The whole point of taking SSRI's is to affect the mind, so they are literally psychoactive.

They are better studied, but the risks you mentioned are associated with SSRI's as well as LSD.

Do you have evidence/study that shows LSD is more dangerous than SSRIs? LSD not being studied as much doesn't mean it's more dangerous...
> But isn't it an anti-pattern to wrap something in an `Arc` when some of your use cases for it are purely single-threaded, and as such you're wasting a certain (potentially very significant) amount of performance on upholding memory visibility and such even when it's not needed?

Yes. You have Rc and Rc::make_mut for the single threaded case. Pick what you need. I interpreted the GP comment as talking about the general pattern of make_mut, not Arc::make_mut itself.

Stylo's multithreaded, we pick Arc. Singlethreaded systems can get by with Rc, but there are often legit reasons for picking Arc, and it's not that bad a hit.
Ten quick tips for teaching programming
Cancer cures are decidedly spotty. First, "cancer" isn't one single disease, it's a symptom complex with numerous etiologies. Some of those are now well-managed -- tunerculin baccilli for yreatment of bladder cancer, say.

Others have seen no progress in 50+ years and continue to have exceptionally poor prognosis.

The biggest advances in medical outcomes are virtually all based on public health, preventive measures, and improved access to fundamental care.
Even if that was true, it doesn't invalidate the fact there is no scientific reasoning behind the theory of chemical imbalance.
well said... in order, then...

1. Read the reference before responding; the study looked (in part) at antidepressant-placebo differences. Also - I can't prescribe placebo.

2. Got anything to back that up?

3. OK

4. Because it implies that some of the 'withdrawal' symptoms are actually recurrent depressive/anxious symptoms (which can include somatic symptoms). Which is different than arguing that all of these symptoms are a consequence of relapse/recurrence.

5. Well, one of the critiques of antidepressants is that, after someone is on them for years, depression can recur... but fair point, not a perfect analogy.

6. Fully understood? It's not even a little understood. What does that have to do with detecting long-term consequences? We have 25 year follow-up data with antidepressants now. Despite lots of effort to find otherwise, show me some solid literature supporting risk.

7. Yup. We should. And we should keep looking.

We also agree that there's substantial harm associated with people confidently posting misinformation - so while I mostly lurk here on HN, I feel that 20+ years of treating mood disorders and 20+ years of pharmacovigilance research gives me the right to push back. Lived experience is critically important, but it does not trump data.
You're calling the Detroit Free Press trashy? You realize that this 'trashy' paper has won six Pulitzer prizes?

You may not realize that the author of this article is a well known serial entrepreneur (ePrize) who also started Detroit Venture Partners with billionaire Dan Gilbert and Magic Johnson.

Also eighteen years ago (though he barely knew me) got me my first meeting with a VC. He won't remember it because he does stuff like that all the time.
Getting confused when exploring Qemu source? gcc comes to rescue
Ethically - you shouldn't log in to other people's accounts, but rather, you should delete the email (and possibly notify them if you can).

I'm pretty sure that legally it's problematic as well.
A Clockwork Orange is supposedly loyal to it's source material, the American edition of the novel.

> This plot discrepancy occurred because Kubrick based his screenplay upon the novel's American edition, its final chapter deleted on insistence of the American publisher.

https://en.wikipedia.org/wiki/A_Clockwork_Orange_(film)#Diff...