skysight-inc/HackerNews huggingface dataset:
At one point during the cancer progress process the cancer is characterized by genomic instability (high mutation rate) and extremely high metabolism(high replication rate). The immune system is actually attacking the cancer cells successfully(in generalizing here in regards to cell types), and this may lead to an optimization process where the immune system is selecting for a cancer cell able to avoid the immune defenses. This interplay creates a microenvironment which is as you described, evolutionary in nature.

As for cryptography, I would argue the biology contains hash signatures and other configurations common to cybersecurity(blockchain turns one problem into many IMO). While there may not be asymmetric cryptography, there is also no pseudorandom business.
> I haven't linked my Aadhaar to my phone yet and if the Supreme Court hadn't extended the deadline my phone would have stopped working by now. This thing is a real and present menace, not just a political science question.

I guess you are attacking this issue keeping privacy in mind. However, from the Government's point of view, the need for linking mobile phones is to have a secured way of authenticating your Aadhaar related transactions. The Government doesn't want to end up in a liability if a situation arises where the OTP was sent to a person who later claims that the number did not belong to him in the first place. The Government is actually trying to protect itself from future litigations.

This is the same reason many services, including banks and credit card companies recommend 2-Factor Authentication. Since Aadhaar is primarily an authentication mechanism and not a tracking mechanism, authentication can only be performed either by scanning your fingerprints or via a trusted device through an OTP (in this case, your verified and trusted mobile number). Since a fingerprint scanner is not ubiquitous but a mobile is, the Government is for now relying on mobile OTP for conducting most authentications.
Canonization for deliverarbility (the enumerated list) can differ from canonization for uniqueness check (ignore all dots).
> is that just the Telegraph being the Telegraph?

Yes. It has its nickname for a reason.
That was interesting, thanks. The story about the red cross food delivery of wheat made me think of whenmy first symptoms were, and it was when I was working at Domino's as a young man and practically lived on pizza... Unfortunately that was 12 years prior to diagnosis! Life has been much much better since .
Fortunately, thanks to your solution, the basic services for the bottom 50% will make them no less free than slaves... (admittedly, history happens like that but it's been continually fought)
Between GraphQL and React, I'm not sure how much Meteor is left in a modern "Meteor" app.
wow great supporting argument. this is the quality we come to HN for.
While you CAN strip periods in the local part of the email and convert them to lower case before checking uniqueness, you do this as the risk of improperly disallowing valid and distinct addresses. A better solution is to check for similar address and provide a prompt "do you already have an account with this address:" rather than completely blocking registration with that address.

However, you should definitely not do these things to the address that you save for the purposes of sending email because then you risk improperly sending emails to the wrong person.

In general, validating the format of an email address is both extremely hard and pointless (since only a small portion of mis-entries will results in an invalid email address).

Pretty much the only way to validate an email address effectively is to verify it by sending an email to it and expecting the user to click an email.
Funny thing, the dude I had in mind was not criticizing the practice. He was giving advice to other employers on how to save money and motivate people.

I always wondered what his employees thought when they read that article and whether the perks worked as nicely after he explained his thinking in public.
Do you mean emails marked as deleted with timestamp?
>As anyone and everyone will tell you, lack of apps killed it.

I am not convinced of this. Aside from the widely used social networking apps, most people just use default apps on their phones for email, the web, and text messaging. Kids play games too, I suppose.

To me, it never felt like Microsoft made a sincere push for establishing Windows Phone into the market. Aggressive subsidies, pricing, and features should have been able to get a footprint. They pulled it off with Xbox, and of course with PCs, so they could certainly do it again with commoditized phone hardware if they were committed to it.
> I just tend to be a little on the defensive about it

Completely understandable! Most people seem to have such a frustrating inability to understand that other people can have very different experiences of the world to their own, and that those experiences aren't wrong.

I am lucky enough that most of my friends do understand mental illnesses a bit better than the average person out there. Some of them who confided their mental health problems with me about the kind of reaction they tend to get, and it's just amazing how ignorant the natural state of the human mind is.

> that I’m taking the “easy” way out through medication.

Call me crazy, but I partially blame the dualist world view of the Western world for that, even if most people aren't even aware that they have been raised with a dualist mindset. This whole mind/matter division makes people think that mental problems have to be solved by thinking.
Show HN: Analytics for Google Payments – Business metrics for Google merchants
You are suggesting that depressed people may want to take LSD in lieu of SSRIs, which is horrendous advice that can, for example, trigger panic attacks in those with comorbid anxiety. Please don't.
I would assume the best intentions for the vast majority of individuals working in the health system. But the economy of that system is one that favors treatment over cure/prevention. I'd like to believe that is a mistake of circumstance and not a design of human greed.
poor are not educated enough about reproduction to prevent childbirth

Many people say this. But it's worth knowing that, historically, lots of societies firmly limited reproduction when they were as poor as (say) most of Africa is now. The methods varied.
This can be directly observed in the case of Shirl Jennings[0], upon whose life the movie At First Sight[1] is based.

[0]https://en.wikipedia.org/wiki/Shirl_Jennings
[1]http://www.imdb.com/title/tt0132512/
To offer the converse, I had a very traumatic event in my life and was put on an SSRI, which helped me function. After almost 2 years of taking it, I didn't think I needed it anymore and I tapered myself off very slowly but regularly, keeping logs and setting alarms. While in the beginning I felt some vertigo and other symptoms, I tapered very gradually, and was completely free at the end of my taper. My symptoms never come back and the SSRI helped me make very real progress on my issues. I'm eternally glad for my SSRI use and a medical system that knows when to prescribe it, as I would have probably not been able to hold down a (at the time, very stressful) job during the initial phases after the event without the help of the SSRI, and it probably would have taken me many years to recover. For those that SSRIs work on, it really works.
I built a major project in Meteor last summer, and it was a big mistake. For the most part, Meteor itself is stable and being actively developed, but many of the packages are experiencing severe rot, and one of the developers of a few of the most used meteor packages recently went out of business and took all their documentation down with them.
> I watch the thing in awe up till and including "My God, it's full of stars"

Interestingly, this isn't actually said in 2001. It is in the novelization but its only said in the sequel 2010. It surprised me re-watching 2001 in the cinema a few years ago to not see it said, so I thought I might be watching a weird recut, but no. How the mind plays tricks.
To put it in perspective, I live in the US and I have an ad for Xeljans stuck in my head. With the tagline "If methathrexate didn't work for you, maybe Xeljans is right."

It's that insane right now.
As someone with diagnosed celiac disease, it took a very long amount of time for me to get diagnosed.

Already when I was around 10 years old I would go to the doctor and he'd say I might have irritated bowel syndrome but really, no treatment would help. I have memories of stomach pains so severe I'd bend over in pain.

It got better in my teens, or I got used to the pain, I can't really tell which. Many years later, when I was 25, I got internal bleeding and a pain so severe my doctor sent me to the ER for suspected appendicitis. However, after an MRI revealed nothing I was sent home without diagnosis.

My doctor finally sent me to get a biopsy to figure out what caused this and it showed that I had celiac disease. I've since followed a gluten free diet quite strictly, but I never get immediate or obvious symptoms so it's very hard for me to tell how well I'm doing. Some times I feel an unexplained tiredness or stomach pain, which probably means I did somehow eat gluten.

This is all to say that celiac disease is a very "murky" condition. Doctors don't always seem to know how or when to test for it (I suspect it's getting much better than 20 years ago). The actual test is quite invasive (again, I've seen there's headway in this space). And even if you confirm that you have celiac disease, it's not always easy to monitor your track record because the damage to your insides is long term and at least in my case I only seem to be able to sense it in more severe transgressions.

The scariest part of it all is the long-term dangers of celiac disease. Eating gluten with celiac disease is linked to a long list of deficiencies and other issues, leading to fragile bones, tiredness and even nervous system disorders (numbness, seizures, headaches, anxiety, etc).

I hope we get better at diagnosing this, it might turn out to not be as rare as we thought!
The Independent ran this story on January 29 2018 [1], and doesn't have a paywall (for me).

They're also using the "bloc" terminology. Given [2] they're likely referring to political bloc, not "Eastern Bloc". There's also the term "Western Bloc" [3].

Clicking the "political bloc" item on [2] leads to political alliance [4] and reads: "A political alliance, also referred to as a political coalition, political bloc, is an agreement for cooperation between different political parties on common political agenda, often for purposes of contesting an election to mutually benefit by collectively clearing election thresholds, or otherwise benefiting from characteristics of the voting system or for government formation after elections."

Not sure how appropriate the terminology is in this context...

[EDIT: "Trade bloc" is probably the correct terminology, but I'll leave my post as-is.]

PS: I also found a video about the subject on The Independent from March 22 2018 about this subject [5] but I cannot listen to it right now so I don't know the contents.

[1] http://www.independent.co.uk/news/uk/politics/gibraltar-brex...

[2] https://en.wikipedia.org/wiki/Bloc

[3] https://en.wikipedia.org/wiki/Western_Bloc

[4] https://en.wikipedia.org/wiki/Political_alliance

[5] https://www.independent.co.uk/news/uk/politics/brexit-latest...
We are in the same situation too, I am curious, you are migrating towards what and how ?
You are saying that. Please don't.
Your sarcasm aside, the problem is the definition of "undesirable" is controlled by a central authority which regards criticism and association with other free thinking people to be undesirable behaviors.
Fairly certain I have, at least, seen the headlines.

I meant my last line not as a disputation against, but only as an indicator that I was, at the time, too lazy to provide references.
You say that like it's a bad thing! Reducing symptoms of depression has saved lives.
Why can't you claim the original accounts?
The 1945 Proposal by Arthur C. Clarke for Geostationary Satellite Communications
I would note that while Gmail is the only one to ignore periods in the local part, many services ignore capitalization and face the same issue.

Many services do strip capitalization when checking email address uniqueness, but this is as much a mistake as stripping dots.
we should be aiming to kill SQL as a language
I've only briefly used Windows Phone 8.1, and haven't seen WP 10.1 at all. What makes it significantly worse than its predecessor?
this is nothing new. people used to do this in maplestory a long time ago for multi accounts under one email
IIRC, not quite literally, but pretty close. The email RFCs in general tend to be much less constrained than one might expect.
The "Chemical Imbalence Theory", although heavely popular and promoted, is largely unfounded on science:

https://joannamoncrieff.com/2014/05/01/the-chemical-imbalanc...
Smartphone Security: You'll Never Guess Who Just Messaged You
Cannot agree enough. Thanks.
Reading the thread, the comment you responded to was using "normal person" as a contrast against someone who had undergone bariatric surgery (which stomach stapling is a variety of).
That's not what any doctor or scientist is trying to do, they'd all prefer a cure. They'd prefer to have treatments that work better, and are continuously working to improve them.

To say that a cure doesn't exist because they are not trying for it is 1) wrong, 2) hugely dismissive of the life's effort of tens of thousands of people, and 3) dismissive of the struggle of those using antidepressants.

If you think there are cures out there that are easily achievable, show it. Otherwise you are just perpetuating facile misunderstandings of a difficult situation.
These downvotes are suspicious. Admins, can you check them, please?
I didn't want to fall into this debate, hence used the politically correct term.

My point being, the other guy is arguing that USA doesn't require identity documents, which is laughable. You need SSN just to earn money in USA.
The email providers do adhere to the spec. The spec does not guarantee that different local parts go to different inboxes.
This article is inaccurate or incomplete in that it doesn't mention the royalty cap. A more fair argument might be "the cap is too high"

To take Qualcomm's POV, consider this analogy: if you had patented the microwave oven and you licensed that to appliance manufacturers. Those manufacturers then decided to offer new ones with a larger cavity for cooking larger meals. They could charge more for this new product, and might pay more in royalties. That's not particularly unfair.

Apparently Apple's suppliers have been making phones under this licensing agreement since before apple entered the business.

I sympathize with apple because unlike the microwave example, they truly do innovate a lot in this space. But they protect their inventions too.
Glad you are in a better place than before, hope the process will go well!

I wonder if there is a form of research that could done by following patients who are receiving this treatment, and track how they wean themselves off of it.
It certainly does. Being much, much more Clarke than Kubrick, I watch the thing in awe up till and including "My God, it's full of stars", and then usually switch off, as I know from then on the masterpiece will be descending into lava lamps and nonsense.

I envy you the progress you'll make when you get around to re-examining some of your faulty assumptions (as we all eventually must, or at least should). Most of us don't have that much room left for personal growth and discovery in our lives.
are those really orwellian though?

they could make an orwellian system on top of it where they destroy government IDs to unperson you, but in and of itself, those aren't very orwellian.
Well, if Netflix striped the periods, THAT would be not adhering to the spec. Netflix's issue is that they have a lax security practice, not that they don't adhere to the spec.
They still do AFAICT (I had to sign up for a Japanese account relatively recently).
Conflicted, actually, as I would have to aggree with the American expurgation of the last chapter from the novel, but I sort of feel I have to take the author's view as canonical - and Burgess famously disliked the redaction.

Anyway, I gave up on deeper meaning in Burgess' work a long, long time ago. I still read him with great pleasure, but that's for the linguistic fireworks and his steamrolling, gutpunching flair for telling a story so you hear the sounds and smell the smells.
I had a few windows phones and it was not the lack of apps in my opinion, but a in a big part, a badly managed store policy that incentivized inflating numbers over actual apps. Searching for any term gave you 4/5 of trash, nonfunctional trash if you were lucky.

Discovery was fundamentally broken, if you had no good idea of what you where doing.
Around 2014/2015 the ecosystem had pretty much no apps or at least functionality missing, besides snapchat and instagram (which was added at some point).
In the sense of a "trade bloc" it's common parlance that has nothing to do with communism: https://en.wikipedia.org/wiki/Trade_bloc
This seems to me to be the trap of a false choice between regulatory power without bounds vs no regulation at all. A much more interesting discussion would be about the proper scope of regulation.

To take your example regarding pharmaceuticals, instead of mandating a particular regime of testing and efficacy, why couldn't the government require products that have not passed that particular hurdle be labeled as such?
My company https://cleverbeagle.com is based on Meteor.js and we have an active customer base. I also run themeteorchef.com (tutorials on Meteor) and while we've definitely seen the hype die down, we still get organic traffic upwards of 25k uniques a month. Dead? No. We see a lot of new interest from overseas (Africa/Middle East/Asia).

Technically speaking, Meteor's in the best state it's ever been: latest Node version, full Babel support (zero config), great accounts system, full NPM support, ready-to-go MongoDB support and access to multiple DBs via Apollo. Things like Atmosphere, Meteor's package system—which have been earmarked to be phased out in favor of NPM—get Meteor some negative press.

It's a shame, too, because having actively explored alternatives over the last six months, the only platform that came close to being comparable (in respect to being fully featured out of the box) has been Firebase. It's not the only option but it's a damn good one.

Meteor deserves far more attention that it receives—miscommunication around 2015 regarding Meteor's choice of UI framework and the Meteor Development Group's shift to focus on Apollo put a serious ding in its trajectory. A guess: MDG had to make a return for investors and Meteor itself—and their hosting product, Galaxy—wasn't growing quickly enough (just a guess).
I was thinking the same thing. This isn't really a viable scam unless maybe Netflix offers multiple ways to reset your password, which isn't addressed in the article. Maybe a text message reset is possible?
Just reminded me of the loss of Dark Matter. :-/
> Even a fairly modest 5% return would produce more income than that, or are the stats excluding investment income?

Perhaps unrealized capital gains are counted as wealth but not income? I've heard that it's possible through some legal maneuvering to "spend" capital gains without technically realizing it.
My wife has found this is absolutely not the case for gmail. She consistently gets firstnamelastname emails instead of firstname.lastname which is the one she signed up with.

To test a theory I told her to login as both using the same password. Both go to her gmail account. Logging in without the dot shows the address as still firstname.lastname.

My assumption at the time is during signup Google strips the dot and it's merely there for cosmetic purposes. The RFCs should treat the dots as separate accounts but Google does not.

Just to verify this is still happening, I also have a first.last account and signed in without the dot. When I got into my account it says 'signed in as first.last'.

This may affect accounts created up to a certain point in time though as both accounts are almost as old as gmail. I got invited back during the early days and invited my then girlfriend at the time (now my wife). If this has changed over time it's become way more confusing.
Sorry I guess I was replying also to GP "That's not communism, though", who seems to be insisting that "communism" means only the mythical utopia.
The scam works because of Netflix's lax security practices around verifying emails. Given how easy it is to make a mistake filling in your email address, and email address should never be trusted until it is verified AND you should make clear during your sign-up process that the user should expect a verification email so they know something is wrong when they don't receive one.
"Cannot stop" is kind of strong. More like "have nasty side effects while tapering off and puss out".

Having been on the Zoloft,I can say is got a black box warning for a reason and should only be taken if you're seriously in danger of self harm.

Shrinks like it because it keeps people coming back. People like it because they're not willing to confront their real problems and want something to numb themselves out.

Just say "No!".
And this, my liberal friends, is what’s “destroying our democracy”. Not some mythical “collusion” of which we have zero evidence after a full year of investigation.
let's just say that the number of times this question is asked: https://hn.algolia.com/?query=meteor%20js&sort=byPopularity&...

does not bode well for any open source software project. there is a vast expanse between "dead dead" and "vivaciously alive". You will not get a straight answer because there is no good answer.
AFAIK in Europe you need to pay taxes only when you convert (sell) crypto currency to real currency.
It really bothers me the number of web services which reject email addresses containing '+' in the local part.

If you're going to try to "validate" an email address, read the goddamn RFCs.
Is there any non-VoIP telephony left?
What's worse is that the longer you take certain psychiatric drugs, the greater the long-term damage it can possibly cause to almost disability. It's being between a rock and a hard place.

I've taken Abilify, Wellbutrin, Seroquel, and a number of other drugs. The biggest problem when you enter the psychiatric system is you go through pill roulette. You take a drug, try it, see what works, and keep trying till you find what works. Even worse is that I entered the system in high school which is a tumultuous developmental period.

One sad personal story is that a psychiatrist started me on a developmental drug. A drug that was approved for other problems but was "in development" for other uses. I tried it and it was worse than Seroquel. Seroquel, if I missed a dose, I couldn't sleep. For this new drug, if I missed a dose, I had a panic attack and if I took it, I would fall asleep. So if I was out too long, let's say traveling, I had to choose between a panic attack or falling asleep.

When I confronted my psychiatrist about this problem, instead of taking me off the drug, he prescribed me medication for panic attacks.
I used to visit Haight / Ashbury with my stoner friends every time we visited SF. When I had the opportunity to move to SF for a job, I almost didn't take it because I thought the Upper Haight was representative of all of SF. I hate that area, and most of the people that bum around there totally suck.
Very few services manage email delivery well enough to propagate email bounces back to their user account info.
Interestingly, for the workers mentioned in the article there are no marginal gains because they are salaried.

I suspect it has more to do with our inability to measure modern work, instead we use a poor proxy for productivity, keeping your seat warm.