skysight-inc/HackerNews huggingface dataset:
On the other side of this, if massive databases of DNA and medical histories were accumulated, it's possible a great amount of human suffering and harm could be solved by aggressively mining this data to find out the connection between DNA and various diseases.

I mean, besides being denied health insurance because of what someone might find in your DNA, why are you so afraid of something even having your DNA, because it might result in GATACA-like society? If so, we need strong legal protections against discrimination by DNA, but we can't throw out the baby with the bathwater.

There's too much good that can be done to human wealth and welfare by eradicating disease and paranoia about theoretical danger should be challenged into laws to protect against discrimination.

What do you think Facebook + DNA is going to do to harm you? Try to sell you a pharmaceutical or medical treatment? A cure for balding or erectile disfunction?
Forget mutual funds. That's closer to a hedge fund.
String benchmarks are so broken.

They way he uses b.N is wrong. b.N is different for different loops so he's e.g. timing 100 iterations of string '+' with a 1000 iterations of builder.WriteString()

Also the compiler can completely null out no-op functions (without side effects) so in benchmarks it's a good idea to assign the value being calculated into e.g. a global variable.

The corrected code is: https://gist.github.com/kjk/6a7d7135ae1e5fa6cd1f0db23d2eaf4d

An example of correctly benchmarking:

func BenchmarkConcatString(b *testing.B) {
for n := 0; n < b.N; n++ {
var str string
for i := 0; i < 100; i++ {
str += "x"
}
gStr = str
}
}

After fixes it paints significantly different picture:

go test -bench=. -benchmem
goos: darwin
goarch: amd64
BenchmarkConcatString-8	300000	5148 ns/op	5728 B/op	99 allocs/op
BenchmarkConcatBuffer-8	1000000	1046 ns/op	368 B/op	3 allocs/op
BenchmarkConcatBuilder-8	1000000	1177 ns/op	248 B/op	5 allocs/op
This is pretty neat. I love how it fits (sanely) in a single file. I've been meaning to get into SDL for a while now, so this will be an interesting read.
Blocknet is an awesome open source project you may want to look into. It's an interoperability protocol and one example use-case project they built on it is a trustless decentralized exchange that allows you to trade directly from your wallet.
It's comments like these that make me think retail investors should never have been allowed to be in charge of their own retirement money.
Saving you a click, it's wireless LTE data:

> The company launched a new version of the Surface Pro on Tuesday that has built-in LTE connectivity, something that should appeal to businesses with remote employees, or really anyone who’s tired of tethering their iPhone to their MacBook with a dongle.

I love that "Bluetooth" is now called a dongle.
Well seeing as you can get two new phones in those 5 years and still pay less than a single iPhone...
I'd urge you to be cautious when interpreting those data. The effect size of most of these SNPs is tiny, often explaining (at most) only very small amounts of the variability observed between groups. This is especially true for things like personality traits, which have a huge environmental component.

So, if finding out the empathy thing is fun, then by all means, keep poking around in your data! Promethease is probably the best of the bunch, and I've run my data through it. Just be mindful of the evidence level and effect size!
Very well written and easy to read C.
I think these guys will, too.
Yes, this can happen. It doesn't invalidate my point though.

I am not accusing women of laziness, which is what you seem to be reading into this.

In the general case, societal expectation is that the man provides. It is an accepted and common "career option" for a woman (especially a good looking one) to simply meet a wealthy man.

The same is not true in reverse.
Found a small bug-- if you accidentally hit '-', then the "amount saved" ends up negative. Couldn't undo it short of reloading the page. Mathematical hilarity ensues...
You get his update for free according to the company.
Do you believe the government is overstepping its authority by stopping people from entering the country without permission? I’m curious if you support an open border and how you want to deal with the ramificiations?
I wonder... GDPR probably covers this, right? So EU citizens probably have the right to have this data erased adter they learn what they need to?
Apparently it only identifies two of the hundreds of BRCA variants that can lead to cancer. Good first step I guess?
Brian Bagnall's books on Commodore argues that one of the reasons the VIC-20 and later the C-64 got proper keyboards was a combination of a costly mistake Commodore did on that front with one of their PET models that got slammed for the poor keyboard, combined with Tramiel seeing it as a way of making the VIC-20 look like a more expensive computer next to the Atari 400.
+1

Back when was re-evaluating where I wanted to go with my career(post-gamedev burnout) I briefly considered getting an BS in EE and getting a hardware job since it's an area that interests me. Did a bunch of research and found similar things.

I think it largely boils down to a couple factors:

1. Everything in hardware has to be spec'd to the teeth since re-spin of HW/Masks can easily run into the 7-figures. That means there's very little flexibility and opportunity for the "10x" EE to manifest.

2. Since everything is still heavily spec'd you get a lot of "replaceable cog in the machine effect".

3. A lot(but not all) HW is really removed from the end customer so you aren't as deeply tied with the business side of things which hurts visibility/etc.

4. Software is just more flexible which means you have a much easier opportunity to be "full stack" and not get pigeon-holed to a specific technology.

At the end of the day I scratch the hardware itch in my spare time and I still find SW a ton of fun. Plus there's a ton of value in being a software dev that can speak/understand hardware language and fit it into the larger picture.
I mean, we literally target community leaders whose sole interaction with terrorists is making sure their village/families aren't in the crossfire. It's not that we don't know this, it's just that we're America, and we don't actually care.

Suffice to say, if Google was deciding who to shoot at, and it came up with a smaller number than they do now, the US would consider that bad design.
Is simply buying the top 25 cryptocurrencies duplicating an index fund?

I didn't know an index fund was just a bundle of stocks.
Your link attributes the 2.5 million victims of the Khmer Rouge genocide to the US. How does that make any sense?
It's a SNP chip and only covers a few common mutations.

To anyone who wants to know for sure whether you're at increased risk of breast cancer, you'll want to get a test that sequences all the known mutations, along with another half-dozen or so genes that can have essentially the same effect as a damaging mutation in BRCA. I'd also urge you to find a genetic counselor, who can help explain the diagnosis in detail, as well as the limitations of the each kind of test.
There are US-designated "terrorist" groups that don't deliberately target civillians and function in a manner similar to traditional armies. Hezbollah comes to mind.
Don't hold your breath. Vanguard tends to err on the side of protecting the interests of retail investors. Hence, they don't do FOREX trading either.
Interesting to note that this was one of the top 10 articles on the front page then in the space of 5 seconds dropped off entirely.

Very odd...
People already post their 23andMe "results" on their dating profiles to say "I'm clean and healthy with good genetics!"

The GATTACA society is rapidly becoming reality, just not institutionalized yet.
Why Apple, Amazon, Google, and Uber are making big health care moves
Imagine that we like sportscars, and you're bragging about your righteous activism to stop those evil carmakers who think they can get away with selling something smaller than a Chevy Tahoe.

You're on well-trodden argumentative territory making early-stage and un-nuanced NIMBY talking points; people are going to be upset. Don't take it personally. I'll assume you just aren't very familiar with the dialogue around this issue yet.

1) The portrayal of sprawl as a lower-greed state is... suspect. Big houses and big yards make it necessary to drive cars everywhere, burn gasoline, pollute the environment with tailpipe emissions, run an enormous military-industrial complex to rig governments and destroy countries to ensure sufficient supply of oil, etc. The status quo for American land use involves an awful lot of resource burn with a whole lot of profit along the way. People have accepted these things as part of the landscape, but are outraged at developers profiting on density. We're looking at this the opposite way: let's be outraged at the auto and energy industries destroying the world, and accept developer greed as part of the landscape while unwinding that damage. YMMV.

2) Pre-automobile settlements (which are more common in Europe, but do exist here) suggest a compact and walkable model, even for small towns, that has a lot of nice properties. Proximity and walkability enable neighborly interactions that Americans just can't have in the built environments you insist on. They enable self-sufficiency for children and the elderly, livelier main streets with more personal interactions and local businesses vs. the big-box-store-with-giant-parking-lot model, etc. HN has an unusually high concentration of people who like the idea of this, and are upset that it's so rarely legal. And it's illegal because of precisely the mindset and activism you describe.

3) "But when a home owner wants to have space they are wrong? You are NOT fighting to have space. No one is taking your land. You're fighting to force other people to have space. Some of us don't want it, don't want to pay for it, don't want to accept the isolation that comes with it... and you've taken it upon yourself to make it mandatory for us to have it anyway.

You don't have to like density. You don't have to want it. You don't have to live in it yourself. All we ask is that when other people want to live compactly, you get out of the way.
I don't think this would be a good idea for Amazon. I don't trust it right now to provide me things that aren't counterfit unless its sold by the actual supplier. Allowing funds to be on its platform without proper vetting seems strange. If Amazon actually wanted to go into the Asset Management space I would actually see it buying something like Robinhood. The problem in Asset management is all of the people who would regularly be retail investors are too smart to be peddled a bunch of random mutual funds and instead try to use index funds. The margins for those are already cut to the bone. I don't see how they could compete with something like Schwab intelligent portfolio either.
How to Crack SBI Clerk Exam by Self-Preparation? – Bank Exam Tips
While I agree that the US has had some bad wars, that article seems a little ... absurd. First line in the tally:

> The U.S. is responsible for between 1 and 1.8 million deaths during the war between the Soviet Union and Afghanistan, by luring the Soviet Union into invading that nation.

Sure, the US did stuff, but you're denying the agency of the Soviet Union (and Afghanistan, for that matter) in actually doing all the killing.

The US has killed enough people directly without blaming it for all armed conflicts since WWII.
> Our version of markets is defined entirely by humans and we can change the rules in whatever way we wish.

no, you can't. everywhere people trade, there's a market. all you can do is raise the costs associated with legal markets, and deprive those engaging in trade of the rule of law.

take a look at the drug cartels for what happens when you try and legislate markets totally out of existence.
I’ve thought since consumer-level genetic testing first came out that there would be a place for a company to do it fully, truly anonymized using tor+crypto or something similar. It’s a bit surprising to me that it doesn’t exist yet; if I had the right background I’d probably go for it myself. There has to be a decent number of people that want to know, but don’t want anyone else to.
I'm not sure your odometer readings qualify as protected information. More importantly, on many cars, it's in public view.

So, what's the difference from the oil shop selling this data or from the insurance agent driving to your house and just looking through your side window?
The Bloomberg title does not include the word “Illegal”, which appears to be an editorialization in the title posted here on HN.
> I suppose being open about it and not impersonating the government is the key difference between ethical and not.

That and being honest about how much value you are bringing to the table. If you don't actually improve on the free version, it is unethical to sell.

And you should never use language to imply a value proposition where there is none. For example, someone else posted a link to some green card scammers. One of their claims is:

> "USAFIS GUARANTEES 100% participation in the Lottery!"

This may be true, but it is still an unethical statement. It hints that this is a net positive vs. the free application the USG provides, but in fact any valid, submitted application participates in the lottery.
https://www.ssa.gov/disability/professionals/bluebook/12.00-...

Pay particular attention to the four criteria in paragraph 12.04B. Understand that SSI is primarily for people who are unemployable and only incidentally for people who are disabled. If you make use of that understanding, you will get your check and your medicaid card.
> so a non government actor can otherwise illegally obtain evidence

A critical point is the police can't directly or indirectly _solicit_ this behavior. That would be a criminal act in and of itself, but it would maintain your 4th amendment rights.
IoT-Powered Transformation of the Health Insurance Industry
If Robinhood, a start up with very few resources, can offer commission free trading, I'd bet Amazon could offer approximately 0 cost S&P500 funds.

If the partnership with JP Morgan works, people could direct deposit money into their Amazon account, auto-invest into Amazon funds, and then spend on Amazon ecommerce. In this model, Amazon immediately saves ~2% on credit card transaction fees, a small portion of which could be used to subsidize cheap or 0 cost investments.

Essentially Amazon could vertically integrate the money that will be spent on their products in the future...
The original Bloomberg article was misleading because there are many laws which concern immigrants, but the US is specifically going after those protecting immigrants here illegally.

Hence my more precise title.
If a condition infrequently happens, a logged debug statement that compiles with the code (or at least travels with the source code) can be preferable to keeping a breakpoint around in the IDE. I personally don't feel comfortable relying on the IDE to maintain an important breakpoint for an infrequent condition. (Having flashbacks of Visual Studio 2008 dropping or moving old breakpoints).
> anonymized using tor+crypto

I'm sure sure how that would work? How do you send a bio sample over the internet?
I would believe that one of our military's lesser goals (obvs winning and preventing our deaths are the major goals) is to avoid collateral damage.

We are not Hezbollah or Russia or Assad. None of them care much about collateral damage. Pretty sure a few of the above believe collateral damage sows fear and provides them advantage, if short-term.
Anyone reading this, please spend at least a few minutes considering an alternative investment approach: In my opinion, most HN readers are technical enough that if they read up on the top 10 coins they would find that quite a few of those coins have extremely unconvincing future prospects- I won't name names, but several of the top 10 coins are (in my estimation) based on EXTREMELY UNCONVINCING ideas.

Before jumping on an index fund, a person on HN should at least consider the possibility that they may be better off doing some homework and reading up on the top 10 coins and then only investing in those that have a convincing technological basis- Index funds are not always a sensible strategy for markets that are as new as the cryptocurrency market, since proper price discovery in asset markets is a slow process that requires time.
Instructions for adding a 3rd party model to LTSpice

http://www.linear.com/solutions/4678
DMCA takedown for copyright complaint
The beta announce blogpost for flutter links to 3 apps published that used it[0]. Also, it seems according to that blog post and the Ars[1] post on it, Adwords may be using Flutter? But that doesn't seem clear to me.

[0] https://developers.googleblog.com/2018/02/announcing-flutter...

[1] https://arstechnica.com/gadgets/2018/02/google-starts-a-push...
Deploying ML Workloads with Azure and Kubernetes
While I respect the FDAs intentions and notable positive actions, I would like to present several articles from reputable sources describing the FDA as a "revolving door" for various industries - an obvious inlet for corruption, dubious research, delayed actions, etc. As I understand it, this is a well known issue.

I believe it is important to be vigilant and critical when it comes to three letter acronyms.

https://www.npr.org/sections/health-shots/2016/09/28/4956945...

https://www.washingtonpost.com/investigations/senators-call-...

https://www.vox.com/2016/9/28/13059538/fda-drug-regulation-r...

http://www.modernhealthcare.com/article/20160927/NEWS/160929...
Yes, this is a good note for anyone interested in doing this. Other things to keep in mind, the paper source, while may be peer reviewed, most likely was not reproduced (a problem in the industry in general), so would be prudent to filter on # of publications supporting the SNP correlation. Also, the report will tell you relative risk, not absolute (e.g. 1.5x increased risk of getting breast cancer). In other words, your absolute risk may be 0.00001, so it can easily be 8x and it won't really matter. The most actionable items I've found for me personally were drug interactions due to genetics. Thanks for bringing up the caveats.
Discussion of original source: https://news.ycombinator.com/item?id=16532788
This seems like a very useful tool, and it provides useful information on our repository.

But in RHEL7 it gives this error:
error: couldn't open Git repository: git rev-parse failed: Unknown option: -C

I assume it requires a later version of git.
Here's the thing, even if we magically only killed the people we want to kill, most of whom probably are innocent, and none of which were given a fair trial: We actually still create more violence.

Right now, to a kid growing up in many of these countries, the face of America is our President (...) and the sound of an American drone on the horizon. Now, one of these days, one of those drones pops his dad. In twenty years, that kid is a terrorist.

Our drone program is basically, the exact thing you'd do if you wanted to guarantee that there'd still be terrorists in the Middle East in two decades, because we're practically founding those terrorist groups right now.
Chinese user accuses Apple's technical support staff of stealing his data
"Dart feels like Java". Great. Now we can have D2EE on the client and server.
Besides the fact that it should cost nothing like 2% of AUM / year, securing the private keys pays for itself when they claim every fork/spin-off coin that distributes based on bitcoin blockchain.
'Corporations Are People' Is Built on an Incredible 19th-Century Lie
They will probably know your milage anyways. Oftentimes the state requires all registered vehicles to be inspected or emissions tested regularly. I recall that my odometer reading was noted on the inspection forms. I also had to note the odometer reading when I registered the car in the first place, though that one was on the honor system. I have no reason to believe the state doesn't share that information with insurance companies.
Earlier post, where the main discussion of this is happening: https://news.ycombinator.com/item?id=16532788
Because in the US, at least, illegal forms of immigration can be a contentious issue where it's proven difficult for many to discuss the issue civilly and productively.
You've posted so many low-quality comments and skirted the site guidelines consistently enough that I've banned this account.

Accounts that post prodigious low-quality comments, especially ones that specialize on all the grandiose themes, are particularly damaging to signal/noise ratio, and that is what we care about here.

https://news.ycombinator.com/newsguidelines.html
If you want to buy this Coinbase index fund, just do this:

1. Log into Coinbase

2. Buy [BTC, ETH, BCC, LTC] with [62%, 27%, 7%, 4%] weights

3. Check back in one year and rebalance

That's it! As an added bonus, you just avoided 2% fees and can "redeem" anytime.
Pre-conception genetic testing is also available through normal healthcare avenues. It even comes with highly trained genetic counselors.
Thanks for linking this. I had a pretty tough time getting quotes on a custom PCB a few months ago. If I'd had this article ahead of time, everything would have made quite a bit more sense!
I had the 800XL and was obsessed with Super Breakout, Boulderdash, and most of all Landscape (later released as Stealth).

OMG I played SO MUCH Landscape...
A Polish Army unit in WWII kept a bear as a unit mascot: https://en.wikipedia.org/wiki/Wojtek_(bear)

However, it would appear that Wojtek was a cub for most of the war.
I'd second this: the case tends to be a bigger constraint than the board (which you can modify at the design stage). Even when you are fabricating the case, the manufacturing constraints are usually more difficult.

Although sometimes you may want to get the pcb working before worrying about the particulars of the case if there are a lot of unknowns in the design.
> And even if you disagree on that, I think it should be their right to sell their privacy for convenience if they want to.

Then it also has to be a right to not sell your privacy for convencience.

Clearly communicate that you do sell my data to bolster your revenue and give me an option to pay more instead.

It's not a legitimate business model to simply not tell me that you're selling my data and then magically have lower prices.
Is that actually a suggestion? If you make an upper middle class salary (like a programmer does) and reasonably control your expenses, I think you only are going to miss making retirement if you have an expensive medical disaster or you invest too heavily in the market then sell during a crash to make rent, or some weird thing like that. I'm not sure if $20000 is going to make your difference
How would it be illegal? If someone came into my business and I noticed something about them, unless it's something specifically protected by law like health information, I'm more or less free to tell others about what I saw. Or even show the public the CCTV footage of what I saw, for example: http://www.independent.co.uk/news/world/americas/espn-report...

This sort of thing might be regulated under the FCRA, but other than that, companies are pretty free to talk about you to others. Just like how you're free to talk about them to others.
I used to get annoyed in these situations but now I think it's a good thing. If the interview is that fucking horrid, the company culture is almost certainly going to suck.

Thanks shitty interviewer for saving me from your shitty company.
Define 'decades behind', please.
Tell us more about your childhood; your account makes it seems less-than-optimal, but I fail to see the connection between the above child-rearing method and something else.