skysight-inc/HackerNews huggingface dataset:
Published August 2017

Povidone iodine in wound healing: A review of current concepts and practices

Abstract

BACKGROUND:
Of the many antimicrobial agents available, iodophore-based formulations such as povidone iodine have remained popular after decades of use for antisepsis and wound healing applications due to their favorable efficacy and tolerability. Povidone iodine's broad spectrum of activity, ability to penetrate biofilms, lack of associated resistance, anti-inflammatory properties, low cytotoxicity and good tolerability have been cited as important factors, and no negative effect on wound healing has been observed in clinical practice. Over the past few decades, numerous reports on the use of povidone iodine have been published, however, many of these studies are of differing design, endpoints, and quality. More recent data clearly supports its use in wound healing.

METHODS:
Based on data collected through PubMed using specified search criteria based on above topics and clinical experience of the authors, this article will review preclinical and clinical safety and efficacy data on the use of povidone iodine in wound healing and its implications for the control of infection and inflammation, together with the authors' advice for the successful treatment of acute and chronic wounds.

RESULTS AND CONCLUSION:
Povidone iodine has many characteristics that position it extraordinarily well for wound healing, including its broad antimicrobial spectrum, lack of resistance, efficacy against biofilms, good tolerability and its effect on excessive inflammation. Due to its rapid, potent, broad-spectrum antimicrobial properties, and favorable risk/benefit profile, povidone iodine is expected to remain a highly effective treatment for acute and chronic wounds in the foreseeable future.

Bigliardi PL, Alsagoff SAL, El-Kafrawi HY, Pyon JK, Wa CTC, Villa MA.

Int J Surg. 2017 Aug;44:260-268. doi: 10.1016/j.ijsu.2017.06.073. Epub June 23 2017.

http://www.journal-surgery.net/article/S1743-9191(17)30536-8...
Beautiful folds in Haskell (2016)
The Nintendo Switch supports OpenGL 4.5, OpenGL ES, and Vulkan: https://wccftech.com/nintendo-switch-supports-vulkan/
Thought this was going to be obnoxious but some really great suggestions popping up. Nice work :)
You can't use one of the lawful basis of consent for this?

https://ico.org.uk/for-organisations/guide-to-the-general-da...
The problem is that the alternative to bringing your pet in the cabin is terrible. In cargo they can be lost like luggage, temperature and pressure controls are not as strictly maintained, the animal is subject to extreme noises and gyrations - it is a scary and traumatic experience. Pets are much closer to children than objects for most people - it is like putting your child down there.

The reason for the abuse of the ESA system is that there are no alternatives provided. Your only options are to torture your pet, or abuse the system. There is no amount of money you can pay to avoid it - you can't book an entire row if you wanted.

I think this issue needs to be addressed, and a process formally institutionalized to allow pets to travel with their humans. It is very rare for anyone to be bothered when a pet is on board - most of the time it brings other passengers joy - in the cases where there is a problem, easy arrangements are made that satisfy everyone.
That's heavily dependent on the regulator in question, and there's 30-ish of them. Since American companies are very unlikely to have a lead regulator, you will need to comply with conflicting rulings from each. In half a dozen languages.
> But I don't know what the PCIe security model is wrt. to accessing other devices, such as the HDDs.

Should also be protected by the MMU for the most part. You might be able to forge interrupts from other devices though. PCI-E message signaled interrupts are just another memory write to a special part of address space, that unfortunately isn't separated by device at page granularity AFAIR.
Maybe they can do that, but that would require piercing corporate veil first which is costly. JoeSchmoeLLC is probably judgement proof. Any attempt to force it to comply would cost a boat load of money.

However, it is a lot more likely that the LLC is owned by those with no nexus to Europe it is extremely unlikely that EU can do anything to punish this company. Hell 99% of web forums have European users.

Maybe it will have teeth against Google/Facebook/Tinder/Match/etc because those companies actually have assets in Europe but it won't be effective against companies with no nexus.
You could also use a C++ core with Qt/QML to target not only iOS and Android but also Windows, macOS and Linux, all from the same codebase.
Gigabyte have a range of small form factor machines they call BRIX. There are lots of models covering a wide performance range. There are a few which are fanless and might meet your power target but they don't state an obvious maximum power rating:

e.g. This one based on an Intel N3350 CPU with 6W TDP

https://www.gigabyte.com/Mini-PcBarebone/GB-BPCE-3350C-rev-1...
Keep doubling until you're down to just one customer, then pull back and double your customers until you charge nothing. Graph that out and write an article on Medium about bell curves.
The form on HIBP uses the same JS client hashing, you can check the HTTP requests yourself in dev tools.

Yes, the whole dataset is available. The first paragraph mentions the release of the v2 dataset and you can read the full blog post here: https://www.troyhunt.com/ive-just-launched-pwned-passwords-v...

You can get the 8.8gb file directly here: https://haveibeenpwned.com/Passwords
This is merely a made up scenario and not a prediction but..

The bitcoin bubble could burst as all the people who only bought it thinking it would just keep going up panic and sell. Nobody wants cryptocurrencies anymore after this event and the negative connotation of anything related to cryptocurrencies/blockchain is so strong that nobody cares to do anything with it anymore and it just dies.
I don't think that's necessarily true anymore. Vulkan and even OpenGL have shown a lot of promise recently, in real world tests. You may be right that it's simple idealism from my end but I (want to) believe that Vulkan is coming along at the right time/space to gain broad support in the industry. I'm no fan of DX12 either, or NVN or whatever it is that Sony has. The low level nature of MoltenVK and likely the future DX12 <-> Vulkan layer will result in a small enough perf hit that it will make sense for developers to target Vulkan instead of 3 different APIs. Perhaps similar libraries will become available for Sony and Nintendo platforms as well. I hope that the trend will continue and one day I won't have to resort to OpenGl ES in order to write something that's truly cross platform.
I use Google Dictionary religiously
Yoga practice, 3-5 times per week has done wonders for my posture and how I physically feel over the course of a day. Doesn't have to be hot or boot camp; I prefer restorative classes.
Russia 'compromised' seven states prior to 2016 election
Even crazier. In France, the setup is similar: you sell all your energy to EDF, and they sell it back to you. I don't know if that's still the case, but a few years ago, the KWh you pay to them was cheaper than the KWh you sell.
I don’t get it. If they have fixed production, why not increasing the prices instead of lowering the demand by begging?
Indeed, capturing IP addresses in logs is exactly like a bridge collapsing and killing people.
> That's why the recommendation is that you strip PII from your logs for everybody.

The problem is that IP addresses — a fundamental requirement for an acceptable network logging system — are considered PII.

If this were about things like names, dates of birth &c. then I'd be in full agreement. But considering an IP address personal information which must be deleted on demand is IMNSHO insane.

> That statement does not hold a lot of force without a link to your business and how big a %age of your turnover you are willing to throw out.

I'm just a guy, y'know? I'm not going to pretend that it would be easy or cheap for others to make the same decision. But it is easy & cheap for me.
We’re Sunsetting CircleCI 1.0
You appear to be suggesting that "intent" defines the shape of law here, but I really don't think that's the case.

By my reading, information becomes personal —and therefore subject to GDPR— when it can be used to identify people. If you've got login timestamps, IP addresses and user records, for legitimate reasons, any other logging that includes IPs is tainted because it takes anybody with that data two minutes to munge them together.

Intent, and actual business use-case play second fiddle to the worst-case, or "what could that data be used for?".
What impact exactly? It's not up to people to disprove that bitcoin won't take over the world, when proponents fail to come up with viable use cases.
If I'm not mistaken, a large proportion of the Flutter team is made up of people who were part of the early Chrome team, many of them having worked on the web for 15+ years.
Basically "only 3% of youtubers can make a living doing it," so in other words, if I randomly select 33 youtubers, and put them in a room together, I'll be able to find one who makes a living from it. Furthermore, if I randomly select 100, one of them will be a millionaire? I really hope this is out of people who already making it their dayjob or something, otherwise this article is pretty stupid.
> the diesel will win just about any street race.

This is really wrong. It's a weird myth that gets perpetuated in America where people don't really drive diesels.

Let's compare a 2.0L diesel Golf TDI to a 2.0L petrol Golf GTI. Same car, same displacement, both turbo engines.

The Golf TDI does 0-60 in 9.0s and a quarter mile of 17.0s@84 mph.

The Golf GTI does 0-60 in 5.7s and a quarter mile of 14.2s@100 mph.

There's a staggering difference in performance there. The TDI is so slow that it's genuinely difficult to find a Motor Trend instrument test on a slower car, because at that point, it's too slow to really bother.

I found the 2018 Rav4: 0-60 in 9.3s and a quarter mile of 17.0@82.
Ultra wealthy are being lured to Italy by low tax rates
Will microservices just die already?
And the panopticon grows... I'm not so concerned about Amazon or Google (though Facebook is creepy, even them).

I'm worried about the access that nation-states security teams have distributed across the entire set of poorly secured, 0-day infested monitoring devices everywhere.

20 years ago I laughed at how infeasible Enemy of the State was, but now it seems feasible (with added drones).

Even the "enhance/sharpen" part seems feasible if everything is packing HD/4k feeds.
Boils down to not keeping entropy in check until it’s unweildy.

Maintainence is as important as new feature development.
Both Xbox and PS are already using AMD-designed chips. Despite new versions are recently released, they both are still based on the previous generation AMD microarchitectures, i.e. Polaris GPU + Jaguar CPU.

This new AMD chips combine new generation GPU (Vega) and new generation CPU (Ryzen). Both are much better than what’s in the current generation consoles.
You do what all those examples you just listed do, you say int is 32-bit which fits in JavaScript number just fine.

Then for longs you either don't support them or suck it up and pay the manual cost, which is what kotlin.js does.

Only dart did this crazy nonsense of an int type that is 2^53 sometimes and has methods like isNaN() on it.
Of course there is no way to know if the array is generated dynamically on the server :)
And yet, I plug an Ethernet cable into a switch manufactured 20 years ago, and it works great, albeit at slower speeds.
If it were true, Formula-1 would use nothing but diesel engines.
The Impact of Zoning on Housing Affordability (2002)
Bill & Melinda have been very active on media in last one month since their 10 tough questions blog post. They are all over the social media with bunch of sponsored/promoted posts on FB/Instagram. And now this Reddit AMA, I am not sure what's the reason behind it but they have stepped up their social media game. There has to be a solid reason behind this uptick. Wonder why?
This chart of U-Haul prices in/out of San Jose (in one form or another) made the news recently.
http://www.aei.org/publication/san-francisco-bay-area-experi...
Not really a problem for EU if JoeSchmoeLLC is really treating this as not a law for them. US and pretty much every country in the EU have excellent extradition agreements. [0]

[0] https://en.wikipedia.org/wiki/List_of_United_States_extradit...
There are various and somewhat complicated electricity regulatory systems in the US, it's not so simple as just raise the price.
> In the early 70's.

There were less lights in poor homes. The more affluent homes had suspended lights with multiple bulbs. (I am not sure how it is called in English). I recall that a lot of homes got more light bulbs and ornaments through the century, as they become more affordable and more hype.

The increase in count came with a decrease in power. The typical 100-150W bulb got replaced by multiple 30-50W bulbs, they do not consume significantly more in aggregate.
[citation appreciated]
Driving a horse-drawn carriage fast and safely takes more skill than driving a modern car. Pulling a carriage isn't a natural behavior for horses. They have to be carefully managed. It takes a fine eye and careful touch developed over years of experience.

Very few tall buildings can accommodate aircraft landing pads. There isn't space due to HVAC machinery and antennas, plus they weren't designed to support extra weight.
Because they aren't needed. We can pretend that the intended user base is your cousin and your grandma if you want but the people that actually use Linux have no problem enabling and disabling services with the command line.
Interesting. I remember the VIA stuff had serious graphics problems (granted it was years ago) but the Geode stuff was worse to be fair, the hardware watchdog basically prevented any GPU events at all. How times have changed.
Well, sorta. The Dart team tried to make it happen, and got a lot of pushback from the Chrome team. I don't think you can claim that Google tried to get it into Chrome.
Comma.ai - Ghostriding for the masses.
If we do decide to raise prices, it it best practice to raise them for current customers or for new customers only?
FTC Chairman Calls Out Venmo Over Privacy Concerns
Texas and Oregon are starting to look pretty nice. Too bad about the cannabis laws in Texas, though. As soon as I persuade the court to terminate my probation I'll consider selling a few properties and getting out of here, too.
“Can anything be done there? Eh, probably not.”

YouTube has recently made it worse. Unless your content is the subscribable kind, you now make zero revenue until you get 1000 subs.
HAHAHAHA, there is no such guide.

Again, the GDPR isn't really a set of rules per say. It's some rules (eg on consent), plus some frameworks (legitimate interest balancing test). The country-specific privacy orgs are figuring out the balancing tests and are promising final guidance, like, totes any day now. Meanwhile, the deadline is 25 May.
You can drive or perhaps take a train. Traveling internationally or trans-continentally with a pet will subject them to lengthy quarantine as well.

I suppose a private flight is an option for some folks.
If you care about places like Silicon Valley or New York, or if you care about social justice across (and within) generations, it's time to research and understand why housing is becoming increasingly unaffordable in the most dynamic areas of the world. It's not due to lack of land.

In California, we have a chance to fix things. SB-827 is a new bill that prevents local governments from banning density near public transit. It is the most radical housing bill in decades, because it rebalances zoning control from the local to the state level. It could result in 3 million new units being created in California, a state that builds <100k per year.

https://standupcalifornia.com (this is a website i set up to support this issue, which i see as the most important political issue for myself and my friends, and our ability to stay in our communities)
The average salaries of software engineers around the world in 2017
Teardown of Netflix's pricing strategy
I've got a sneaking suspicion this is one of those clever, elegant, kind-of-awesome-thanks-python, yet entirely evil things you can, but never actually should do in a production app.

Is there a use case for something like this?
This sucks...
Ring has been providing subpar service and promises that remain unfulfilled. It was Cleary working on cutting costs to get ready for a sale.
Which is why Tesla is putting so much emphasis on voice controls.
The function takes in the hash prefix and sends the correct file in response. That decision has to be made somewhere.
I must downvote you as per HN rules for joking - unless you were programmed to do so because you are of the femirobot caste. In that case, carry on Hitler.
It’s all about supply and demand for ads.
> Your measurement of time and space will always adjust to ensure light travels at a constant speed.

Enough with the metaphors already, the measurements don't do anything, you, or rather phyisicists and the like do measurements, and they adjust numbers normalized to c=1 because how else would you do it. There is no way to synchronize clocks because of the CAP theorem, nevermind relativity.
Basically the optimal tool for offline maintenance is a live disk which will actually work if the drive is screwed up.

Basically you were holding it wrong.
That's just dandy. Show me software that uses it. This is 2005 all over again. You make that deal. You talk to that support. You prove me wrong, please do! The better support, debuggers, and feature requests will come from the native API.

PLEASE prove me wrong.
Companies generally make these types of acquisitions for two reasons: customers or technology. Since the technology Amazon already has for the most part, they're obviously acquiring them to leverage their customer set (... or prevent a competitor from doing the same).
404?

Title has no google hits.
What I think would be even better is to exercise to commute - many folks I know have the joy of this option e.g. biking 10mi or less to your work and showering there.

I'm more excited about hybrid bikes (allowing even older folks to be more mobile) than self-driving cars.
You could do that with themes.
Publishers Hope Food Books Will Grow Interest in Healthy Choices
Oregon sucks. Don't move here, I mean there. But, Texas is very nice.
>Families with kids and those with only a high school education predominate among those moving from California to its top destination states (Texas, Arizona, and Nevada). College-educated 18 to 35 year olds led the way among those moving to California from its top feeder states (New York, Illinois, and New Jersey).
Offices and shops used neon lights. It lits as well as LED or better, but consumes a lot of power.
They have the ability to unlock your front door, so "your paper towels were replaced on your holder" is a legit option.
I assume Ring will never give the promised HomeKit support now...
Subscription Billing Best Practices
I couldn't read this on my phone – it seems GitHub doesn't format Jupyter notebooks on mobile Safari at least. Here's a mobile readable gist: https://gist.github.com/dfee/00c1d7e70abfdbc3ef03d8ec165a104...
Have you really lost sight of what this this thread is about? It’s not your view of historical figures in their time, it’s about your endorsement of autocracy in general and Xi in particular. If we’re at the point of judging the rulers you picked by only the standards of their day, I’d say you’ve ceded what point you had.

It is kind of pleasant to realize that you were just arguing for the sake of it though, rather than some bizarre conviction in autocratic stability.
Consumer protection laws, such as the Credit CARD Act of 2009, don’t apply to businesses.
When will it be available on Linux?
They ruined firewire with the idiotic trademarking of the name Firewire causing other companies to brand their products: IEEE 1394, 1394, i.LINK (Sony) and Lynx (Texas Instruments). That lead to similar problems that USB C is having where you have confused people asking questions such as "Is this 1394 camera compatible with my iMac?" or "Oh, i.LINK is the same thing as Firewire AND 1394? So I was able to use all of those things this whole time?" Things got a little better but combined with the per port royalty vs $0 for USB it was bound to fail. And that's a shame because it was a nice bus with very low latency, overhead and memory mapping. It would be perfect for creating small Linux clusters or distributed systems with just a few 1394 cables between machines. Superior to USB in every single way save for cost.
what an odd hangup. how does this have anything to do with numpy specifically?

the suggestion that jumps out is to just learn about algorithms.
Not a list of exercises, but Julia Evan's pandas cookbook has been incredibly helpful for me.
Of all the wonderful things that we're capable of as technologists, I think we can figure out a way to strip raw-IP addresses from log-files once we don't need them any more.

I'll need to figure out to handle this on the data I'm responsible for at the moment. It's boring and it doesn't help the product, but it's not supposed to. In idlewords' terms, I feel like I'm finally purging toxic waste: http://idlewords.com/talks/haunted_by_data.htm
Very interestingly on a similar topic here is Netflix's pricing strategy. https://www.priceintelligently.com/blog/netflix-pricing-stra...
Deadlocks aren't actually all that bad, in my humble opinion. They encourage stability when the major factions disagree strongly but have similar levels of support. The alternative is whip-lash policy changes as control changes, which I think would be much worse.

I think the real problem in America is too much centralization. If more policy was made locally, it could be adapted to match diverse local conditions and attitudes, and the preferences of other regions wouldn't be as threatening. Unfortunately the winner-take-all aspect of centralized politics makes the sides more entrenched.

Do you think the current Chinese government is helping or hurting with the attitudes that lead to the appeal of "elect me and we'll take Taiwan back by force"? Seems to me there's some danger of things going badly if they don't prep the ground for democracy and lose control somehow.
I don't think Google has a view: go to Google I/O, you'll find in one room the Chrome team harking at how PWAs are the future of mobile apps, and in the next room the Android team harking at how their new features solidify their advantage.

There's no coherent view as to what they want mobile to be, just teams pushing their own things.
I tried to find the source of the quote on epilepsy from Hippocrates. It appears on Goodreads [1] but not in the version on classics.mit.edu [2]. A different version can be found at [3], but it also does not match. It seems that people are paraphrasing the message of Hippocrates's "On the Sacred Disease". Can anyone confirm?

[1] https://www.goodreads.com/quotes/153826-people-think-that-ep...

[2] http://classics.mit.edu/Hippocrates/sacred.html

[3] http://www.atheistrepublic.com/gallery/hippocrates-men-think...
Texan here. We welcome y'all with open arms, just please don't turn Texas into the places that you left.
the result for banking is that European banks refuse to let Americans open bank accounts

depending on the levels enforcement I suspect the same will be true of many popular online services for GDPR: you check the "EU citizen" checkbox and you're banned