skysight-inc/HackerNews huggingface dataset:
Leaving aside for a moment the issues of healthcare being wrapped up in a system of regulation and entitlement that makes a healthy marketplace impossible, and growth in demand harmful rather than beneficial. Putting that to one side, the reason why present day preventative care does little to the numbers is that (a) most costs occur due to age-related disease, and (b) present day medicine can produce only marginally positive outcomes at great expensive when it comes to aging and its consequences. It is still outperformed in many areas by lifestyle choices.

Sufficiently good preventative medicine will save money, because it will address the root causes of aging and thereby reduce risk and severity of age-related disease, while lengthening healthy and overall life span. It doesn't even have to be cheap. It just has to be less cheap than the cost of attempting and failing cope with aging.

But in practice it will largely be cheap.

Senolytic therapies to clear senescent cells are a pharmaceutical approach to age-related conditions that improves the situation for near all individuals and pathologies of aging, cost-effectively. Those tested to date reduce inflammation, partially resolve loss of regenerative capacity, turn back atherosclerosis, restore loss of tissue elasticity to some degree, effectively treat osteoarthritis, effectively treat fibrosis, clear out many forms of bad immune cell, remove a contributing cause of Parkinson's disease, and so for for a much longer list. The reason it will be so much better is that it targets a root cause of aging, a form of damage, and directly repairs at least some of it (25-50% of senescent cells destroyed in some of the measured tissues for some of the approaches).

One of the candidate therapies, dasatinib/quercetin, costs ~ $30-100 / dose. Take it once every few years.
Well, those are not really SMEs with high quality jobs either...

I'll happily accept your word that Amazon's sweatshops are better than X's sweatshop - but that just makes more shitty jobs...
Your comment got me wondering if cactus juice is a thing, and apparently, it is.
they had similar wording to the cookie things. you had to say for what feature the cookie would be used, at the time the user was actually starting use of the feature. advertising? logging in? ....in the end everyone just says "to use this website" and use for whatever (but mostly ads)
>For some people drinking good coffee is exactly like experiencing a fine wine.

I would phrase it differently.

Americans have become conditioned to accept high prices for drinks. For lots of reasons, but mostly because they are real money makers in almost every place that sells any sort of drink.

I mean, it costs up to $6 for a bottle of kombucha, and I know people who go through a couple of those a day. The next logical step is a $20 coffee.

Meanwhile in Europe you can get a good espresso for a euro.
Yep! But do you really think that the difference in opportunity between the rich and poor in America is larger than anywhere else?

For instance, can a poor person get rich in America? If so, is this easier/harder than other places? Once rich, can they start a space program if they wish? Is this easier/harder than other countries?

If the point is that when poor, you don't have the "opportunity" to start a space program, I agree :). I also think it's an odd way to define opportunity, and I'm not sure it indicates anything negative about America.

Anyway, I expect that this is tangential to your actual point, so I don't mean to to drag us too far down a pedantic side street :).
And in truth, the "github crap" is clicking "Fork" and running "git remote add". Pushing and filing a PR are the same process.
And RISC-V has a "machine mode" which the OS doesn't know about, which is effectively a place to do microcode.
On linux, I don't use ESC at all anymore, I just press alt + [a normal mode key], while in insert mode. Like `alt + j`, which will leave insert mode and move one line down.

Some alt based sequences are really useful:

* alt + e, a : leave current parenthesis and continue inserting (eg, while typing parameters for a function)

* alt + shift + a : insert mode at the end of current line

* alt + shift + i : insert mode at the beginning of current line, with indentation

* alt + p, a : paste before current position, and continue inserting

Maybe there's a modifier key with a similar behavior on macosx?
They'll need to predominantly do them on polar missions, in 2017 SpaceX had only 5 polar missions. Also, for missions that are already launching large numbers of satellites (like Iridium flights; 4 of the 5 polar missions in 2017 were for Iridium) this may be harder as it will require more fuel and a relight after an extended mission in its primary payload orbit.

EDIT: grammar fix
>To those of us who value freedom in the sense you belittle, the extreme alternative to what you proposed is being enslaved to one single thing, the size of those 2000 things you relied on plus another 5000 things that you don't but some other people do.

And how is that working out for you?
Every decade has its unstoppable juggernaut of a business, with endless articles pontificating that the government should step in and dismember them, and then some new business emerges that takes them apart, and the argument repeats itself.
Once a month look at year-over-year total returns for VOO, VXUS, and BIL

keep 100% of your portfolio in one of 3 funds: VXUS, VOO, BND

use chrome, not firefox which is broken
http://stockcharts.com/freecharts/perf.php?VOO,BIL,VXUS&n=25...

VOO Highest? buy or continue to hold VOO

VXUS Highest? buy or continue to hold VXUS

BIL highest? buy or continue to hold BND
Unix: Building a Development Environment from Scratch (2016) [pdf]
There will be no practical way to determine that until we've colonized it.
People want to pay more for coffee than they currently pay. I realized this after seeing the popularity of Philz Coffee. Only drip coffee, for about $4 a cup, much longer wait than sbux and lines out the door.
California has a lot of ag industry and they are interested in making as much money as possible.

California doesn't have a collective consciousness.
Ask HN: Software to build a voice assistant on a Raspberry Pi?
Wow that is complicated! Thanks for sharing, it's good to know how time consuming this could be if I take it further.

It sounds like Overpass is the way to get the data I need - once I figure out how to reference it in Overpass (network/relation details).
→ Curso Criar Vídeos Animados Para Negócio Digital
In isolation, yes, you are very right. But history is anything but that, and there is always a context and reason for why things are the way they are.

I am from India, and I know bias when I see it. Classism and racism is systemic in India and whether you want to believe me or not, a person from a religion or upper caste will prefer a person from the same group. I am not going to claim that this exact same thing happens in the US, but I will not believe that it doesn't happen at all.

The thing is that the memo even mentions the problems with inherent bias, and then mentions that we need to have "open" dialogue.

The open dialogue is hard to happen when one group has been suppressed for generations.

What are you going to tell them? - Ok, we are sorry for what we have done, now we are going to be equal and you can compete for the same things? One group is dirt poor and disadvantaged, and the other has always enjoyed enough wealth to get proper education. How is that level playing field?

Minorities need to be given a hand up, at least for a generation to really make a level playing field.

As for your examples, yes, it's unfair, but that's what the under privileged group got told for generations. I guess life really is unfair.
I think the requisite reference here is to the notions of positive and negative liberties, a distinction famously formulated by Isaiah Berlin. See: https://plato.stanford.edu/entries/liberty-positive-negative...
As a person from Eastern Africa, am curious why you chose Eastern Africa & not North, Central West or Southern Africa.
That sounds like a good argument to stop allowing california agriculture to externalize the cost of water.
That Time an Astronaut Lost His Wedding Ring in Space
Have you looked at Algolia?
People will tell you, that there is big gaping crypto vulnerability in Telegrams client-server crypto because it is not secure under CCA. In fact this is only certificational weakness (ie. attacker can replace message with different ciphertext that encodes exactly same message). The crypto is somewhat weird, but it is clear that motivation for the weirdness is getting small ciphertexts.
Me too! I spent weeks of my life on that game and never thought to ask what it even meant when they said that.
I think you'd be on shaky legal ground there. In any case, it's a major hassle to reinstall your OS
How is stealing a physical object at all similar to "stealing" an idea? These are two very different things, and I think the fact that we even call it "theft" and "stealing" is bullshit, because it clearly isn't.
Same for me. I once visited a coffee farm at Kona: the coffee was nice, but not that special. (For one thing, the coffee was in thermal carafes, with small paper cups next to it. Think Trader Joe's.)

I feel how the coffee is prepared matters more than where it is from. Or maybe I lack the taste buds to feel it properly. Oh well.
Paul Graham, Jeff Bezos, Charlie Munger, Naval Ravikant, Sherlock Holmes, Richard Feynman, Edwid Catmull, and so on... the majority of the people on the list are most certainly _not_ salespeople, and many of them are world leaders in their respective fields.

Sure, it's unlikely any of them will be remembered as Marcus Arelius (Feynman has a decent shot, though). But that is an incredibly high bar that leaves behind much potential insight. It's also definitionally not attainable by someone who is still alive today, so we have to keep that in mind.
Both my grandfather's and all their brothers got Alzheimer's and they all had regular exercise routines. My mother's father was even running marathons up until he had Alzheimer's. I'm sure it helps but in the end you can't outrun death.
How could it be cheaper to have a driver in each car instead someone watching 8 videos at once? They'll probably want cabin cams anyway so you wouldn't even save that expense.
> solar system internet

What exactly are you picturing here? Because of light-speed considerations you'd have semi-isolated networks at each major body, and bodies connected with special high-power high-latency links. And those links might as well be direct, only needing a handful of dishes.

Is there a reason to scatter little relay satellites all over the middle of nowhere? Or do anything else that needs many many rocket launches?
Here is one written in Java: https://github.com/stefanhaustein/expressionparser

In addition to a simple math expression evaluator, examples include a BASIC interpreter and a simple computer algebra system O:)
Yes, it's unfortunate that you can articulate the problem so well and still not see it for what it really is. But in the interest of carrying on, I am copy pasting one of my replies -

In isolation, yes, you are very right. But history is anything but that, and there is always a context and reason for why things are the way they are.

I am from India, and I know bias when I see it. Classism and racism is systemic in India and whether you want to believe me or not, a person from a religion or upper caste will prefer a person from the same group. I am not going to claim that this exact same thing happens in the US, but I will not believe that it doesn't happen at all.

The thing is that the memo even mentions the problems with inherent bias, and then mentions that we need to have "open" dialogue.

The open dialogue is hard to happen when one group has been supressed for generations.

What are you going to tell them? - Ok, we are sorry for what we have done, now we are going to be equal and you can compete for the same things? One group is dirt poor and disatvantaged, and the other has always enjoyed enough wealth to get proper education. How is that level playing field?

Minorities need to be given a hand up, at least for a generation to really make a level playing field.
> you will find out what should actually be grown.

the problem with that is "what should actually be grown" has different answers depending on whether you value profit or feeding people.
please no, amazon makes life better, saving me so much time to focus on other things.. i do NOT want to go back to the time before that
Spectre can be completely mitigated, it's just another headache to deal with. =(

Essentially, you just have to buffer up more stuff and clear the misspeculated entries so nothing is left lying around that could leak information. Comes with a cost, but chip companies don't have to give up on OOO/speculation entirely.
Interesting point, I'll add that we don't see many desktop computers any more. Kids or those wanting to learn to program don't see the whole machine. Instead we have these slim downed devices that require existing knowledge to take apart and put back together again.
> Except you have to use <amp-img> tags instead of <img>

Those are just custom elements: https://html.spec.whatwg.org/multipage/custom-elements.html
There network will have minimal (30-40ms) latency hit vs ground based systems because there satellites are 300-1000 miles up vs the 20k miles that the current geostationary ones are at.
I've been using a hotspot from the Calyx Institute https://www.calyxinstitute.org/ as my sole internet connection for the past year and a half. It's a nonprofit which offers an "unlimited" hotspot on the Sprint network for $500/year. I get 16.3Mbps down and 3.96Mbps up (per Google) and streaming video works just fine. You might want to check that out instead.
Well the simplest one to code up is just bisection of segments until every one is under your error threshold. This is obviously far from ideal, but depending on your needs might be acceptable.

If you are trying to approximate a function where the domain of the function is important then it’s fairly straightforward. See De Boor’s book A Practical Guide to Splines, which IIRC has a chapter or two about this.

If instead you are using your spline to approximate the points of a curve without worrying about the parametrization, that gets trickier. Try doing a google scholar search (keywords along the lines of “spline variable knots cagd”), there are a pile of papers analyzing different approaches.
The fact that so many of Google's employees could demonstrate the degree of ideological hysteria which they demonstrated greatly concerns me, and has a direct bearing on the 1A context.
You must live in the late 20th or early 21st century. Your claim doesn't hold true for most of human history.
https://a16z.com/2014/09/05/why-amazon-has-no-profits-and-wh...

So on the contrary, I still am looking for a non-bullshit treason not to do it.
Right, except it's the fault of countries like UK and Ireland (among others) for creating the conditions for legal massive tax avoidance. And the EU for not smacking that down as a priority immediately. When I relocated to the UK one of the first things the banks did for me was create an offshore account (Isle of Man, I think it was). I thought to myself, this is strange, who do you think I am, Pablo Escobar ? This was Barclays.

And all my Amazon packages to London had Luxembourg return addresses.

Sorry, Europeans, you can blame big American tech companies for dodging taxes all you want, but it's hypocritical when you legally allowed the conditions for them to do so.
It's very easy to agree with what you say, but something that I think is difficult to answer is breaking it down into real numbers. How much do you think somebody should be paid for moving boxes? Again you'd probably like to respond with a phrase like a 'livable wage', but I'm curious about an exact number with a natural understanding that it'd be higher for workers in e.g. San Francisco and lower for workers in the middle of Idaho.

To avoid making this a trap question, I'll give you my response to any number ahead of time. The US GDP/capita is $52k. So if each and every person received a perfectly equal share of every penny created, that'd be a total of $52k. And society certainly sees value in creating a much stronger economic incentive for e.g. being a doctor or an engineer than for moving boxes. So where would you put the number? It's not easy to answer when you consider that the current average salary for our box movers is already about $26k, or 50% of a perfectly equal share of all wealth generated in the nation.

---

And I have one other entirely separate question for you, due to the phrasing of your question. Would you have been happier with Amazon had these jobs simply not existed? There's many possibilities there. In the future these jobs will likely be eliminated through automation. Other business situations, such as Apple's, enable them to avoid US blue collar labor by shipping the jobs off to factories in China where conditions and lifestyles are substantially worse than low wage jobs stateside.
> If you are vegan, you aim for a whole food plant based diet.

I know lots of vegans that eat junk. You are making things up.
I've done this as an amateur. Medical grade ketamine isn't the hardest thing to find and I do not have the money to do it professionally.

A few years ago I remember my first time taking ketamine at all I went from near suicidal to feeling completely fine pretty much over night.

I think that the "side effects" as the article put it are actually pretty helpful. The dissociation gives you a sort of third person view of your problems and life that is very helpful in my opinion.

I found that eventually it stops being as effective but I think there has been some permanent changes. My lows don't feel as low anymore. I still have down periods but they're no where as bad as they used to be.

More recently I've just stuck to antidepressants (I take an NDRI) and vitamin D3.

I've tried some analogs of ketamine (2fdck, dck) and hope they take a look at some of them to see if there can be similar effects.
I was told by my optometrist not to get laser surgery to correct short sightedness because as I get older my eyes will naturally become longer sighted. So if I reset my eyes through surgery now I would then need glasses to correct long sightedness in about 10 years... I was 40 at the time. Basically I left it too late. Surgery for just 10 years without glasses is barely worth it for me as I only wear glasses for driving.
It's been taped out as a research chip, but no production runs.

Naturally, like any OOO-issue processor, it supports speculative issuance of load operations to the memory system (or it wouldn't be worth the effort of OOO-issue).
The Artist and the Innovator
Possibly I misunderstood you, in which case I'm sorry. We often have to guess at what people meant in their comments. On the other hand, we're no different from other readers in that respect, so if I guessed wrong, almost certainly others did too.
> ... I think you can see a substantial difference between say React Native and a Cordova app, right?

Absolutely.

I see a difference between this and discussion about transpiling vs compiling. One of the things I appreciate about transpiling is that it is a different word that does not attempt to take a word with established meaning. I obviously don’t think it’s a pointless distinction—but then I don’t find myself bothered by technicalities when it comes to technical things that need clear meanings.

I think the JS community has brought this problem upon itself by trying to lay claim to the word native when talking about web apps or apps built with web technologies for platforms that don’t rely on web stack as core/native tech. If they’d just choose/create a word that doesn’t already have established meaning on the target platform or technical space, I don’t think there’d be disagreement or confusion.

It’s the same thing when people claim Electron apps are native apps. We all know they aren’t really—they’re web apps wrapped up in a native window, relying on a full browser stack and JS VM to do what they do. I think it’s awesome people are working on things like Electron, because it’d be amazing to have an easy toolchain to create cross-platform native apps that is accessible to everyone. But they aren’t going to be native, and definitely can’t claim to be truly native until someone turns it into platform-native code that doesn’t need a VM.

Ultimately, we wouldn’t need to have this discussion if particular words loaded with extant meaning weren’t being misappropriated by the JS community. At least where mobile/desktop platforms are concerned, native means building with and using UI, threading, performance, libraries, APIs, and a whole host of things directly. I don’t look forward to the day where the JS community co-opts the term to the extent the platform-native tech has to start calling itself by some word other than native.

EDIT: Full disclosure—I like native technologies on various platforms, and don’t particularly find myself interested in building mobile/desktop apps in JS, HTML, and CSS.
I think we'll soon have a better idea of how this plan might pan out. OneWeb is trying to do this first, and the first of many satellites are already built[1][2]. They'll start launching later this year. [3]

I'm very curious to see a real-world use of their system when it's fully up and running.

[1] http://www.oneweb.world/

[2] https://twitter.com/SpaceTechAsia/status/959300225394339841

[3] https://spaceflightnow.com/2018/01/22/testbed-for-canadian-d...
Proving the existence of life is relatively easy: we just have to find some. Proving that Mars is lifeless is flat impossible. We can't even be sure our definition of life is sufficient.
Gold if you compared it with what? I think that Arch wiki is superb and have a lot of more information for the experience user than the FreeBSD manual which is excellent only for the first approach.
See Lawrence v. Texas.
I think you just get used to the glasses you have. For example my current pair of glasses are a high index lens, and adjusting to them took two or three days of being slightly dizzy when walking around.
Med grade K pops up for about 140 USD a gram. It's not hard to get insulin needles. There are guides on how to IV on the internet.

This would likely last much shorter then an infusion as there's a limited options for setting a running IV as opposed to just a single injection.
You can set Windows Defender to not proactively scan.
It's not surprising at all that widespread, cheap, effective means to reduce body odor would make it less socially acceptable to have body odor.

There are many unpleasant aspects of being human that we tolerate, because we have no other choice. Through time, technology is created that helps us deal with more and more of these things. That's only natural, and good.
Can you make a native button in React Native yet? When I first tried it, there was no button component at all; later, they added a component[1] that emulates (almost correctly) the look and feel of a native button but is not actually native.

I tried to implement a native Android button component myself (i.e. hook it up[2] using Java code), but the problem I ran into was that for the button to compute its desired size, React Native wants to do the measurement step on the JS thread, before the actual button is created (so it can't be asked for its size). And the built-in components' implementation of measurement looked really complicated, so I gave up on it.

[1] https://facebook.github.io/react-native/docs/button.html

[2] https://facebook.github.io/react-native/docs/native-componen...
Seems like you could stop him by not letting him own a gun.
Given that Russians created Telegram, why does anyone trust it?
I would love to know what plans does the eu have to stop routing so much internet trafic via the uk once brexit effectivly takes place.