skysight-inc/HackerNews huggingface dataset:
Their sales data is not available. The MinION program does not seem to be designed to finance the company, though it might actually be profitable. The PromethION on the other hand, is selling faster than they can ship the devices.

Their valuation is not about short term sales. Their technology really is somewhat of a holy grail. There is no "simpler" way to read DNA in terms of technology. Everything else involves complicated biochemistry. Illumina beats Nanopore Technologies right now because of the scale of their machines. But they can't scale them down much further without losing performance. The most efficient Illumina machines will always be cupboards or bigger.

No competitor can come up with something better than ONT. Nothing smaller, for certain. The only way to beat Oxford Nanopore in the future will be to implement a very similar nanopore sequencing scheme.
It's a Health Plan. People go out of network in Kaiser all the time- basically, once Kaiser's default system can't handle you (complex organ transplants, advanced rare cancers, etc), they send you to a place like UCSF, and have negotiated the cost structure.

There's no guarantee KP won't bankrupt you, but it seems better than most.
How can you be sure they will respect privacy? That's the $10,000 question here.
Brexit, problem solved, everything legal for the UK government.
Is this perhaps where the monarchy having no real power falls down - Parliament is Her Majesty's, if her Parliament fails to abide by her laws then she should act, she didn't even need to use the courts, she should really just have the relevant persons held "at Her Majesty's pleasure" ... the only problem there is the complete breakdown of democracy and the rule of law ...

The MPs have failed to dutifully carry out her wishes, assuming she wanted the HR laws to be followed, Parliament makes the laws but it is Her Maj that - in our pseudo-democracy actually decides to implement them.

Heads on spikes.
Another man with a related story was Jan Karski [0]. Interestingly, Jozef Cyrankiewicz, future communist PM of Poland who testified against Pilecki, smuggled Karski out from the Nazis.

[0] https://en.wikipedia.org/wiki/Jan_Karski
Self-control and cognitive control are not the same thing
Flexibility. So can update the OS easily. To have the choice of running Windows or BSD, etc.
> “I want this specific provider at any cost” is somewhat of an edge case

Not really. I want someone I can trust. For my primary care needs, I have established trust with someone and know their capabilities, their business practices, and their character. I don't want to roll the dice with someone new when I can still go to them.

Example 1: My primary care provider(been seeing him for 10 years.

Example 2: My dentist (been seeing him or his predecessor for 30 years)
I love Kaiser. One stop shop for most things, easy, efficient, unified records. Highly recommended!
If you're going to make the colossal claim that the US "largely financed" Germany in WW2, you're going to have to present better evidence than obscure factoids like 4 out 7 IG Farben board members being American (and [citation needed] on that as well).

The claim that the US was "largely fascist" after WW2 also seems... questionable.
Dang. That’s pretty compelling.
The existing API already features ability to integrate into any event loop. See rd_kafka_queue_io_event_enable() to provide a file descriptor to be notified of incoming data.
The researchers concluded: “While both cognitive control and self-control may be observed when we control and steer our behavior toward the pursuit of long-term goals, they may depend on different underlying processes such as the avoidance of distraction – in the case of cognitive control – or resisting short-term temptations – in the case of self-control.”
Wait, so all of the hand wringing over the crappy UI was pointless because it was actually a case of miscommunication?
Let's see, LQR is an optimal control technique for linear systems given a model.

Given a linear plant model and a PID controller, you can compute all the classic control metrics like phase and gain margins, settling time, and even how the controller would perform according to the LQR metric.

That's the theory. All linear. Theoretically it's as appropriate to apply LQR to a nonlinear plant as it is to apply PID.

If you tweak the four LQR matrices (say, for a second-order system), and couple the gain matrix with the output of a linear observer (Luenberger), that combination system should be able to generate any PID controller. It's an over-parameterization, however (which is why I think PID controllers are ubiquitous. Not many parameters). Many settings will produce the same controller.

If anyone knows a reference that discussed PID and LQR like this, I'd love to see it
Not that I expect anyone at VICE to understand basic physics let alone thermodynamics, but the amount of energy and labor necessary to heat all city streets would surely surpass $1B anywhere in the U.S. ...
How much have you spend on Mixpanel??? ;)

How did you get to insights/assumptions like "If people don’t do [action] during their first 7 minutes in their first session, they will not come back"?
I think the fact that (as someone pointed out) Coinbase is a YC had some help as well. No one likes it when the fight starts coming into their own backyeard.
http://www.oregon.gov/ODOT/RPTD/RPTD%20Document%20Library/ma...
No, Cobra rules are all defined in Federal law. The OP could have gotten care at the time and asked the doctors to defer billing until the insurance resolved (or just submitted to the insurance company anyway and followed up later). If the doctor/hospital balks you can show them your Cobra paperwork to confirm it. But yes you have to pay the premiums.
Wait...except the decrease in care when transferring a patient to a new doctor is the EXACT reason health care professionals say we can't put a cap on working hours and introduce more doctors to help with the work-load.

They always says it hurts the patient's care. I think there is some truth to both sides, but we'll probably never know. Too many people are making out like bandits in the current health care system.
Glad you found it!

Can anyone tell me if this could have been found in the library of congress?
The issue is that "child rapist" implies "poor judgment of character". This implication cannot be made because there are plenty of accounts where "non-child rapist" have "poor judgement of character".

No one is arguing a child rapist is okay; the issue other posters are having is that it is a incorrect argument.

Any further "but what if's..." are simply assumptions that do not have proof.
Haha, awesome! Glad if it helped in anyway.

Are you putting your code on github or such?
(edit: disregard the question. Its obviously at: https://github.com/geonnave/primg/)
I live and work in New Orleans. I don't live in the best part of town.

Bad stuff happens here like everywhere but I very very rarely fear for my safety.

This is a definite case of 'control/corruption in the name of safety'.

How do we stop it?
I can think of a couple other reasons:

1. With cryptocurrencies now blackhats have a buyer that isn't a corrupt foreign government. A lot of organizations are quietly paying ransoms right now. It's better than the alternative.

2. Who is this Satoshi, really? Colour me a little bit skeptical that someone was able to pull off this level of anonymity for this long. I'm not saying it is likely (<5% chance), but it is at least possible that Bitcoin is the American answer to the declining power of the greenback against the Euro and Yuan over the next couple decades.

3. Map out the crime networks and scoop them all up all at once then ban or regulate cryptocurrencies. Essentially what you said.

But I agree, it doesn't make sense for governments to cede this amount of power, and the small positive value that they enable (like actually being able to reliably send money to friends overseas) is dwarfed by the corruption they enable.
Keeping an Engineering Notebook
Would the Allies stand a chance if the Soviets didn't help? Would the Allies stand a chance if the Soviets allied with the Axis?
>I think they're just pocketing the difference between the market rate and what their costs are.

This is baseless and not really possible.

Insurers must spend 80% of premiums (85% for large group plans) on providing care for their insured.
Strava is opt-in, so I don't know what default standards you mean. You can track activities on other platforms that aren't designed to be social networks.
> I plan to move far away from cities very soon for this and several other reasons.

So you're going to move somewhere where you have to be on the road more, thus increasing the odds of your dying in an accident (unrelated to hacked autonomous vehicles).

I'm gonna stick to my city that's building walk-able neighborhoods, and push to have autonomous cars relegated to certain corridors. You know, participate in society, rather than act like I'm a special who needs to be coddled, and avoid people due to lack of social skills.

Go ahead and move though. Seems cowardly and self-righteous. Hey everyone, ship goods all the way to me! The one who would rather avoid you all, because my work experience has me convinced I can see the future.

Computer nerds need to get better at stats and probabilities.
> So you would like to make your statements, but not to have them challenged?

Oh dear, I didn't even point single statement yet.
And sometimes the truth is that the author really thinks that way,they're probably a defensive, mediocre person in software.
I have a cool way to use these transcripts. One question... I noticed the MIT Licence... but did TED authorize this? or have these just been scraped without explicit permission?

(No judgement, but wanted to know this before using the texts in a project)
The Co-authored-by trailer isn't actually new. In fact it was already being used by over ~1M commits on GitHub before we launched the feature! :)

The git-core commit message conventions docs mention it (https://git.wiki.kernel.org/index.php/CommitMessageConventio...) as do the OpenStack commit message convention docs (https://wiki.openstack.org/wiki/GitCommitMessages#Including_...).
GovSat-1 Launch
Indeed they help you most often during turbulence, I think that's more common than a crash. I was traveling recently with my 2 children, 1 and 2.5 yr old. When the child is over 2 he needs to stay on his own seat, but the seat belt does not shrink to the size of the child. I think it was at least 10cm loose and they refused to give us a baby seatbelt because of rules. Simply stupid, with all the safety measures that you have in a plane why is this being overlooked?
I think a lot depends on the situation. There are a lot of companies who would pay a lot of money to have a technical person on their team who follows best practices, doesn't slack off, and is reliable. This is a low bar, but many engineers don't live up to this and end up causing as many problems as they solve, including being hard to manage.

If, as a contractor, you are professional, easy to get a hold of, and treat your work seriously you'd be invaluable to any company who could hold onto you and a lot of hiring managers secretly know this.
I was thinking about this recently. I already knew from personal experience 25 years ago that I couldn’t trust what is reported in the news (if I know that they lie about things I personally know the facts about, how can I trust them on everything I do not know the facts about?)

It seems like every time there is a report about a science discovery, people jump out of the woodwork to complain about the state of science reporting and how the science news is wrong and misleading. I do not have the background to read and understand scientific journals to find out the truth, and it probably wouldn’t matter if I did. There are stories about fake articles being accepted and published by reputable journals all the time.

The recent revelation of deep porn shows that someone like myself, without the skills to analyze videos to know if they are fake or not, has to assume that all videos are fake. The same applies to images, audio, and other media.

When I can trust no text, video, audio, images, etc. to not have been manipulated and to have no reputable authority that I can trust to help me to distinguish between truth and fiction I am left adrift having to assume that everything I do not personally experience is false (and even then I know that human memory is flawed and no two people experience the same event in the same way - so I cannot even trust myself).

This seems like a rather nihilistic and cynical viewpoint, but knowing that I cannot trust anything is actually rather liberating and fills me with optimism. I cannot trust the bad or the good things that are reported.
You mean humans?

Because there are currently no fully autonomous vehicles on the road where I live, and only a handful of Teslas.
In retrospect this is probably what I should have done.

edit: but the thing was, I trust them to give me good advice. The HR providers. I figured, well if they haven't said anything about deferred payments, it might not be applicable to my situation so I never brought it up...
The Mistakes You Make in a Meeting’s First Milliseconds
>The SEC said that for the first time in connection to an ICO fraud, it has appointed a third-party custodian, or receiver, to secure the firm's cryptocurrency holdings. Those assets include bitcoin, litecoin, bitshares, dogecoin and bitUSD.

How exactly do they plan to do that? Are they raiding machines for passwords/private keys as a part of asset freezing?
Very interesting article. It's impressive the engineering effort you are making here.
For me, it was more helpful to determine what my minimum rate should be rather than the maximum.

My calculation is basically whatever the average equivalent full time employee in my area makes multiplied by two (and that should be any average dev’s minimum). At this rate I only have to put out an easy average effort, there is no need to over-deliver, though sometimes it just happens anyway and the client is unexpectedly delighted. And some clients think my average effort is over delivered.

I find that charging more and forcing myself to overdeliver for every client adds to stress, and makes me less likely to take work. I don’t like quoting a super high rate because it comes with extra value-add promises. Also, quoting high means I probably only have energy for that one client, instead of maybe 3 average clients. I like having more sources of revenue as opposed to just one big one.

Knowing my minimum rate makes it easy and straight forward to give my client an idea what I will cost on the spot, eliminating any drawn out negotiation or having to feel them out to see what their budget is, and barely any need for me to “prove” my worth. If they can’t accept my minimum, the conversation is over.
By your own admission, the UK is driven by expediency. The state can do essentially whatever they want, as long as they have a Really Important Reason. Get rid of jury trials for northern Ireland for a few years, because it's cheaper than properly protecting juries? No problem!

The American constitution exists to say that there are some things the government ought not do, even if it makes their job harder, and that if you truly must do those things, you have to convince more than 51% of the country that it's okay. Californian cities can take their own people's guns away, but it is not their place to take them away from rural Kansas, where a cop is an hour away at best. You have to have at least minimal evidence that somebody did something before you can ransack their house.

I readily grant that our current practice is to play silly games to say that these lines aren't being crossed when they are (border phone searches, stop and frisk, you name it).
Single payer does not mean non-profit, providers would still be for profit.
Kaiser has both HMO and PPO plans, although depending on your employer you might only have access to the HMO (e.g. if they went with another insurer for the PPO).
In the UK the Queen passes the laws, so there seems no reason she couldn't issue a writ making particular actions of MPs unlawful.

Presumably she doesn't because she rather likes the money and the palaces more than she wants to settle the question as to how you have a parliamentary democracy and monarchy with "you don't".
Changing economics are another consideration. The faster adjustments can be made—for instance, to optimise the operations of a machine in a factory—the bigger revenue gains tend to be. That means data are often best analysed as they are captured, which needs to be done locally. The costs of transferring, storing and processing data in the cloud can be avoided too.
It's plugged into the mains, but regardless, Apple replaced the battery a couple of months ago, currently has only 19 charge cycles.
What happens wages dont keep up with inflation?
Many countries throughout the world has seen a lot of proffessions wage increases slowed or failing to keep of with inflation. What do you think the long turn consequences of this will be?
Sure, and I'd bet that they are going to be changed in the opposite direction than what you'd (presumably) want, to ensure that it's harder to use cryptocurrencies in an anonymous or tax-avoiding manner.

For example, it seems that currently USA sellers are allowed to interpret sales in Bitcoin as "barter events" and not submit the usual cash payment form 8300 for such sales, but (as you say) laws can be changed and I expect that this won't be the case soon, and the changed laws would be likely to require any legitimate seller to report such transactions (for non-small amounts, like the form 8300 limit of $10000 USD) and refuse them at all if the buyer wishes to remain anonymous. All it takes is a tiny change in the laws, extending the sentence "Cash may also include cashier’s checks, bank drafts, traveler’s checks, and money orders" by adding a definition of cryptocurrency. It's not done yet simply because the gov't is slow to react.

Anyone considering the future of cryptocurrencies should consider not only the current laws, but how the laws are likely to be changed to extend the current regulation principles to cover cryptocurrencies - the governments around the world have a rather clear and long-term consensus about the goals and principles of that regulation, and changes in technology simply mean that the written law will lag a few years while that consensus is (re-)implemented in laws covering the New Thing.
Looks interesting .. as a SW Eng, I find Udemy very useful for these hw courses. Thanks for the pointer!
A few donation centers near where I live no longer accept books because it is costing them money to dispose of them. Outside of books that might have special interest; I had a few proofs/advanced copies I have sold and even purchased. A few first prints of some novels are valuable as well but a library or other won't know that. In the end, if you don't need the space just keep them on display. If you have lots they work great as a sound break on a wall you have noise issues with
Not always - the other way to mitigate billing inflation is to increase premiums (which would explain the last 20 years).
I wouldn't call it hand wringing, as I think all the points were valid, but yes, the employee sent out the message he intended to (the real alert over the test alert).
This is still a weak excuse for allowing politicians to break the law. It's like saying we shouldn't go after child molesters because they might kill the police so they can keep molesting children.

>By prosecuting (former) politicians, you're not creating disincentives against abuse of power

Do you think prosecuting people who committed crimes creates a disincentive against crime?

>you're disincentivising loss of power.

The same could be said for (former) leaders of drug cartels and mafia bosses, but we still go after them (as well as the current ones), don't we?

Loss of power is already by default highly disincentivized, which is why people want to hold on to it for as long as they can. It's also why we enforce term limits and have checks and balances. However those checks and balances are quite toothless when you elevate politicians above the law.

"We hang the petty thieves and appoint the great ones to public office." -Aesop
Show HN: Knowledge Trybe - Read and share intellectually stimulating articles
A brief plug for anyone interested in starting in this space. I'm an engineer at RedoxEngine[0] where we build a system to transform the many varying forms of Healthcare data into an easy to use JSON API[1]. This has proven to reduce development time and increase the available pool of Healthcare Organizations that your product can connect with[2]. I'm pretty happy working here and seeing the types of solutions that our product enables/expedites. If you're interested in the space feel free to PM me regarding questions. It's an exciting time to be working in the rewarding field of Healthcare Technology!

0: https://www.redoxengine.com/
1: https://developer.redoxengine.com/
2: https://www.redoxengine.com/customer-stories
Arbitrary code execution through unsanitized browser UI in Firefox
Welcome to HackerNews of the last year or so.
I recently saw a very interesting CFD study by NASA recently on drone configurations, where they found that a hybrid version with front rotors below the frame and rear rotors above was significantly faster, since the wakes interact less. Wonder if it's been tried on racing drones?

https://www.nas.nasa.gov/publications/articles/feature_hybri...

(The flow simulation and visualization in the above link is so insanely high resolution it's borderline pornographic.)
They also know they're paying a lot of devs 80-150/hr who are hard working, don't slack off, are reliable, and follow best practices.
And they have an HR/Invoices department who would constantly harass them about paying that much for a dev, if they even approve it in the first place.
Selling Skills That Every Salesperson Needs
Sure, somehow I'm worth ~$140k/yr (plus benefits, etc) to my current employer as a FTE (who bills me out at a much higher rate to our customers, I'm sure), but I'm in govt contracting - it's a different world.

How to find private sector clients willing to pay good rates? I have no idea.
Checksum offloads and protocol ossification
Open library of fundraising killer metrics
The Motherboard article has this written:

> Check out this paper from researchers at Iowa State University for a deep dive into the CO2 footprint of heated pavement versus traditional snow removal. Spoiler: Heated pavement is better, even when heating systems are powered by coal.

This got me curious given how counter-intuitive it seemed. I opened the paper itself ( https://lib.dr.iastate.edu/cgi/viewcontent.cgi?article=1007&... ) and did a string search of "maintenance" and found this gem:

> METHODOLOGY AND DATA SOURCE
This study only considers the operation phases of both traditional and heated pavement snow removal systems, which means that construction, maintenance, and rehabilitation phases are not included in the system boundaries

So basically they ignore the costs in building and then maintaining the system. Also the paper seems to be highly focused on airports. Presumably this simplifies the problem greatly.

Regardless the author of the article seems to have found the title of a paper and then whipped up an article without every really thinking about things.

Ignoring all that, it is of course true that salt is very damaging to both infrastructure and the environment. Personally I really like how Sweden does it (at least Stockholm and other relatively dense areas) and just throws gravel on top of the snow. I've heard people complain, but I personally love it. It's like having crampons on the ground so you don't have to put them on your shoes. I run outside most of the winter and rarely wear spikes.