skysight-inc/HackerNews huggingface dataset:
I have worked in biotech / biopharma for the last eight years as a founder / venture investor / operator coming from a non biology / chem background. It is an amazing space that needs more smart people from other domains

Most engineers / tech VCs have been making initial forays into this world through bio-IT / software driven drug dev. This is potentially a really promising space, but I'd suggest starting with biopharma bc 1) it has been generating some of the best returns in venture the last few years and 2) being good at bio-IT requires a good understanding of biopharma and drug dev

Biopharma / therapeutics has generated some of the best returns in venture the last few years but is still mostly dominated by specialist VCs and has almost no seed ecosystem (most startups that end up getting venture funding are seeded within the top funds), so there is huge opportunity for seed investors to find the good opportunities outside of the top 5-10 life sci funds. The number of funded biotech startups and seed investors has not increased in a decade despite a doubling in venture funding and the best m&a / IPO environment ever. It is possible for companies to go from seed to IPO in under five years and $5-10B+ m&a in ~5-7 year timeframes (some good timely examples here: https://lifescivc.com/2018/01/two-carts-two-charts-dissectin...)

Finding the best opportunities in biopharma requires identifying the best science. This requires investors to be at least conversational in biology, chemistry and drug development and to utilize advisors / consultants / PhDs to dive deep into specific tech

To orient yourself to the world of biopharma investing, id start by reading more of Bruce booths blogs (he is the author of the post I linked above). He is one of the few life sci VCs who blogs and is also a pioneer in seed-series A biotech investing

Also I'd recommend following biopharma news and funding / m&a activity. If you see any investors / people you recognize in press releases call them up. If you see a deal that interests you, take a look at the scientific publications from the company and reach out to the authors and other scientists in the space to hear their thoughts
It just takes one malicious ad on the payment page... and the tempation to shove ads into the face of every customer and his dog is big.

Think about java updates and a certain antivirus product as a great example of insane greed :)
Isn't LibreTaxi based on telegram? My brother expressed an interest in making his own one man cab company and i mentioned alternatives to uber and lyft and one of them was libretaxi. I had no knowledge of what it did or how it worked but we were looking at it literally just the other day and now it is gone. My brother can't use lyft because he doesn't have a good enough car for them and uber doesn't cater to our small town. So scrach libretaxi off too.
Don't worry, the SDC sensors and hardware will be cheap, and software open sourced soon enough. It will be a technology for everyone like the cell phone - even the poor will have equal access. We're good at making cheap hardware, and there will be a push to make it available to everyone.
I gave him mine on your behalf :)
See also: https://en.m.wikipedia.org/wiki/Fldigi
Except your list of misfeatures is actually a missing feature and a list of bugs. No one would claim Steve Jobs or Apple was ever perfect, just that he wouldn't have released these blatantly obvious misfeatures.

Can you think of anything similar to these weird misfeatures? I'm genuinely curious.
Computer sound devices tend to have a roll-off filter just beneath the Nyquist limit of the DAC. So, higher-end audio devices that can sample at 96 KHz or higher could presumably do so.

But, then, you'd need speakers that can reproduce it and a microphone that can pick it up, too. Also, reflections are surely a problem at higher rates. The examples shown are well within the range of human hearing (but, old modems had to work within the bandpass range allowed by phone networks, which was rolled off at something like 8 KHz).
YouTube’s live TV service is now available for Apple TV devices
Could you please stop posting unsubstantive comments to Hacker News?

https://news.ycombinator.com/newsguidelines.html
I didn't miss it; I address it in the very next sentence - "If the data is good (i.e. it represents the real world properly), then the ideologies should be questioned." There is a if-then clause there.

The point about mugshots shows perfectly the problem of what happens when the data is biased.

But then the corollary is, sometimes the data is good. The relevant quote from article:

> If you try to manually “ignore race” by not letting race be an input to your model, it comes in through the back door: for example, someone’s zip code and income predict their race with great precision.

This is what happens with loan or crime data sets, and it made plenty of noise in the news recently - but only the kind of noise in which people say it's obviously the algorithm that's broken, because it doesn't fit the "polite fiction" they'd like to believe.
Hennessy was an incredible steward at Stanford, and I'm 100% sure that he will be a difference maker at Alphabet. I don't see him taking the position if he didn't have an incredible vision for the future that he could drive.

The intro to this video talks a bit about his accomplishments as president.

https://www.youtube.com/watch?v=ApTQ1bfKXyY

This video is probably more in line with the interests of the community here (Stanford Seminar - Entrepreneurial Thought Leaders: John Hennessy of Stanford University):

https://www.youtube.com/watch?v=tB3oAg0wuYg

I was in the audience when he announced the launching of the Knight-Hennessey scholarship. It was an incredible speech. He was always an incredible fundraiser, but putting together a $750M fully endowed scholarship program is a heck of a way to say goodbye to the university.
Waterloo Teeth: A History of Dentures
I think every old world civilization has attempted at one point or another to claim they were first. Outside of the natives and the Norse and maybe the Polynesians in SA, it's usually psuedohistory relying on circumstantial evidence.

https://en.wikipedia.org/wiki/Pre-Columbian_trans-oceanic_co...

It's weird how much we want it to be true though.
What you always need to know about Quantum Gravity?
There is a very active discussion going currently that the cost of the program could be way higher. Like 10x - 20x higher.

Eventually the numbers will be clear.
It's been a LONGGG time, but Access (Access 97) used to include essentially a limited version of Crystal Reports built in.

Also, the Jet database engine was more or less freely available as a part of many Windows products. Even if you didn't have Access, you could still use the Jet database engine programmatically, IIRC. And/or pass such functionality along to coworkers who didn't have Access.

In many office environments, essentially if they gave you a PC with Windows and Office on it, you had some level of ability to database. A lot of clueful office dwellers with no ability to requisition anything more, made their lives easier and more interesting by taking advantage of this.

These days? I've been away from such environments for a good deal of time, but given the nature of humans and their workplaces... I wouldn't be too surprised to find that essentially not much has changed, in this regard. But that's just my commentary; I don't know.
learning qur'an
It's a joke. Every chapter in the book has a section titled "Fallacies and Pitfalls" describing commonly held beliefs that should be avoided for the topic of that chapter. See for example page 58 here:
https://books.google.com/books?id=cM8mDwAAQBAJ&lpg=PP1&pg=PA...
Living style guide generator for everything
Wow, just heard that they got on Roku's platform earlier today, this is a huge move for YouTube!
National Writers Union and Nautilus Settle $60,000 Non-Payment Grievance
C'mon, all you are doing is selling yourself short
Wouldn’t they simply require a reserve that is proportional to the amount you’re charging for the recurring payment?
Ow ok. Perhaps because they where Irish, I remembered it differently
Websites can use IndexedDB to test for PBM. Firefox and Edge don't support IndexedDB in PBM. Chrome supports it using a temporary database.
We've banned this account for obvious reasons. Would you please stop creating accounts to break the site rules with?

https://news.ycombinator.com/newsguidelines.html
Could you please not post unsubstantive comments here?

https://news.ycombinator.com/newsguidelines.html
You might want to take a look at https://www.everbutton.com/. It basically wraps Stripe’s API so you can drop front end JavaScript without any backend code. Much more customizable than PayPal with all of Stripe’s benefits.
Neat! One of the RAID mirror drives at home is showing some pre-failure signs, so I'm looking to insert a hot spare. I guess HGST or Toshiba is the way to go!
eBay | https://www.ebay.com | San Jose | Software Engineer (backend) | Full time | Onsite
We are looking for 4 back-end software engineers(all levels) to work in Risk product development team, which is responsible for managing seller and buyer risk in eBay marketplace. Our core product is a decisioning platform that handles ~ 200 M requests per day integrating with all major flows on eBay.

Technologies:

Backend: Java, Jersey based REST services, Spring batch based batch jobs, Event/Messaging systems

Frontend: Angular JS/bootstrap,

Tools: Git, Jenkins

Datastores: Oracle, Mongodb, Hadoop and Cassandra

I'm a developer in this team. Shoot me an email at baathreya @ ebay . com
Personal attacks are not allowed on HN and we ban accounts that do this. Please post civilly and substantively, or not at all.

https://news.ycombinator.com/newsguidelines.html
I admit I've kind of lost track of the argument you're making here.

We're talking about why there is no premium on BTCUSD sold on BFX. If confidence in BFX having the reserves they claim to have drops, traders will want to get out, which in this case means buying cryptocurrency other than Tether. [1]

Outright faking the ticker is, IMO, not realistic for an exchange with as many users as BFX has. The discrepancy would stick out like a sore thumb.

They could raise BTC prices on their own exchange using USDT, which they control and can create at will. That's what this whole discussion is about, in the larger context. But that would, again, lead to a premium on BFX, which isn't there.

They would therefore need to be suppressing the price, which they could do by cooking their own books, selling BTC they don't actually hold. This would be very foolish, as they'd be creating an exploitable market inefficiency. People would buy on BFX and sell elsewhere, and slowly (or very quickly) BFX's reserves would diminish until they would have to stop processing withdrawals of BTC. See mt. gox.

[1]Of course, since other exchanges use USDT trading as well, it's possible this damps price premiums somewhat. But you'd still expect a premium on BFX et al. compared to, say, Bitstamp.
In theory this is a much better approach than Earth satellites: the farther away an object is, the smaller its motion will appear. With hundreds or even thousands of "fixed" data points incoming, it should be possible to develop an incredibly accurate model for position in space.
"Whether a pension is sustainable into the future is something you should factor in before committing to operate and provide pensions."

Again, you act as if this is simply black and white.

Meanwhile, they work to vote out everyone who won't commit to doing so, do everything in their power to make it complete political/etc suicide to not make the pensions happen.

It's just as obscene to do this, and then not expect that, eventually, someone who says "well wait a sec this will bankrupt us", will have to undo it. That's on the people who did it, the union leadership, and the state.

It's not like the unions can't do math. They knew this would happen just as well, as did their membership, and they fought tooth and nail for it anyway in order to "get theirs" while they still could. This argument that "well they should and that's okay and it's everyone else's fault for letting them" is just silly. If that's how you see unions "helping people", good riddance to them. There are very very few innocents here. The innocents are the other taxpayers, honestly. And yes, they absolutely all are villains for the part they play in doing this.
Again, it's 100% not the one-sided thing you present where the poor unions negotiated a fair deal against the evil state and people got screwed later.

Do you want me to pull up the history of votes in these states, and how the union usually campaigned heavily for decades against any attempt to reduce or taper the pensions (IE not give them to new recruits) at all to try to make them more sustainable right up until the state had to kill them entirely to avoid bankruptcy? This is why people got "screwed out of their retirement" (in plenty of cases, they voted to approve the union doing this, so ....)
Can you recommend a book that would serve as a useful prerequisite to CA: AQA? Based on your recommendation, I flipped through the first few pages on Amazon, but it felt a lot like Algebra 2 without knowing Algebra 1.
If their offshore holdings are profits made offshore, then shouldn't those profits be taxed offshore? Is this what Trump really did, taxed offshore before EU does it, so the EU taxes will be much lower?
Surface Pro 4 owners putting tablets in freezers to fix screen flickering issues
Apple, Dropcam Veterans Launch Owl Security Camera for the Car
We love your many technical contributions to HN but I'm sorry to say that you've frequently been slipping into (a) ideological battle and (b) outright incivility when posting here, and it seems to be getting worse. Could you please roll that back? It's really a problem. These things destroy the container that makes HN viable as a site at all. We need senior users like you to strengthen it, not destabilize it.

I realize that it can be hard to bracket out one's reactive emotions when the internet is doing its provocation thing, but we need everyone here to try. Our common interest in having a site that doesn't suck needs to take precedence over our annoyance at each other's ideological views.

https://news.ycombinator.com/newsguidelines.html

https://news.ycombinator.com/newswelcome.html
10 easy-to-use GUI tools for Mac users
Game Over for Coal: Scientists Nail Down Pesky Perovskite Solar Cell Problem
Also, when talking to them they were stuck on requiring photos of a passport as a requirement for the recipient of the payment if I remember right. In the U.S. That's a non-starter as many people don't have passports and even if they did wouldn't be used to providing them in a business setting, so we ultimately passed.
What makes you think i think the state of corporations running things is great? :)

I just don't think unions actually solve any problem in that realm, and any problem they could solve, i believe there are more effective, less risky, less problematic ways of doing.
I believe they allowed people to cook and sell meals in their neighborhood.
Have you looked at Rev.com? Video transcription is $1/min. Accuracy is pretty good too. If you need to tweak it, it's just a text file with time codes.
Cherow ECMAparser 1.0 beta is out
Still in beta stage, but with improved performance.

URL: https://github.com/cherow/cherow
This article says if you only rent one home, the new tenant protections don't apply.
https://www.portlandmercury.com/news/2018/01/24/19626335/por...
But we know Columbus wasn't the first. The surprising thing is that the Atlantic is less difficult to cross than you'd think. It's somewhat common for people to ride the current to the New World in just a few metres of boat[0].

The hard, and scary, part is planning to bring enough supplies when you don't know when you'll see land.

0 http://www.yachtingworld.com/extraordinary-boats/undaunted-t...
Where do we go after Git?
Well, this is the case with every state with possible exception of Delhi.
From a user perspective, I wouldn't trust a site that uses it's own payment processor, unless you are Amazon, Ebay etc. Double that if you ask for credit card details. Redirecting to a well-known payment processor (PayPal etc.) guarantees that I can pay safely.
> Which is why I’m having trouble picturing the market for this. How big is the overlapping region in the Venn diagram of “Linux users” and “people who need a hand-holding not-really-a-database”?

Probably big enough. Most developers would probably reach straight for a database but anyone outside the developer group (sysadmins, hobbyists, laymen using linux) could probably benefit. Maybe even low level devs that never touch databases, but they could probably learn sql just as easily as kexi. Another one would be any group of non-devs that have or could build a database but want an easy way to build a front end for it, think of the sort of things you'd build a bare bones web front end for.
>We IT/OPs people are the glue that holds these visions to profitability - have more power than we acknowledge

From a senior sysadmin, hear, hear!
AMA w Developers of TIM: 100M Txns/sec
When Ebay first started requiring Paypal, it made sense - Paypal was clearly the frontrunner for online payments and Ebay's homegrown effort was a pale comparison. Also Ebay was a real powerhouse that could move the needle with a decision like that.

Today I feel like Paypal has a lot more traction than Ebay, and this is going to be a big flop for them. As a consumer I don't want to sign up for yet another payment service.
Would this work between two modern laptops a few feet apart using built in mic and speakers, assuming some ambient noise?
It's not acceptable to be this kind of a jerk on Hacker News, regardless of how Dutch or otherwise "direct" you might be.

Could you please read https://news.ycombinator.com/item?id=16288896? Your comments are increasingly vandalizing this site, and it's dismaying.
I might be sounding negative, but the current PM is known to be someone who just promises a million things. This is just a prop for 2019 because he has absolutely destroyed the economy and the RBI.

I seriously doubt if this will actually be implemented ever. This is the magic of India, They won't deny insurance, but when the people will go to create insurance, there will be some or the other issue with the system and they won't be able to apply for it.

Also the media is a sycophant of the govt so nobody will question it and on the exterior, it'll be shown that they did provide insurance although nobody got anything.
Time spent not doing our own designs (and instead spent memorizing how to use magical frameworks) is time not spent advancing our technical understanding.

That's a false dichotomy. The time it takes to "memorize a magical framework" is far less than the time it'd take to learn how to write code to do what the framework does. Consequently you can learn a framework and some other technical understanding in the same time it'd take you to only learn enough to implement your own version of the framework. In most circumstances that's actually more beneficial to do that. You'll be further forward in your understanding of the technical stuff.

You're also assuming that frameworks are written by individuals. They're not. In the case of some large frameworks it'd be practically impossible to implement what they cover on your own. You simply can't learn the underlying principles and then implement them all in code yourself.

It's definitely worthwhile learning the basics of the languages you use, and you should be working on things that improve your code and understanding as much as possible, but it's very likely in most cases that will mean building on top of someone else's existing code rather than implementing everything yourself.
You seem to be arguing back, but this user was agreeing with you, saying this behavior should be for all browsing, not just "private" browsing.
> You’re intellectually lazy

That's a bannable attack on HN. I'm not going to ban you because the thread is about "directness". On HN, however, it is not ok to be a direct asshole, so would you please not post like this here?

https://news.ycombinator.com/newsguidelines.html
Phones are of course more slippery than ever as they've grown and slimmed and've developed a whole touch screen on one side.

But I also wonder what material you'd manufacture right onto a phone that doesn't just cheapen it to most people, like the lame helmet they give you when you rent a motorcycle. A cool brushed metal feel vs the cracking rubber and yellowing rubber on my girlfriend's cheap android.

Either way I'm not sure why one wouldn't put it in a case. It's like 10 years too late for anyone to be marveling at it.
This is very generous, thank you so much.
It took me a long while to come up with a response to this I liked, but think about it this way: there is, maybe, a 10^-a prior climate change destroys life as we know it, right? But my prior for God, heaven, etc existing is, alas, 10^-b, where b >>>>>>>>>>>>> a. (never a 0 or 1 prior kinda guy, even if I know that is dumb in some scenarios, like tautologies and impossibilities, yadada). Too many more factors would have to be revealed to me in terms of the existence of God that I would then believe that a is of similar value to b, if that makes sense? ie that they have similar probabilities (or rather, utilities, which matters since heaven is probably +inf and catastrophe of all life is MAX(badness) which we might as well call -inf, right?

So, not only is -Cost * P(calamity | investment) >> -Cost * P(calamity | not investment), Cost(investment) < [Cost(calamity | no investment) -
Cost(calamity | w investment)], so its a rational purchase...

sorry if this is at all unclear, i can clarify anything
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These are all remote positions. You'll be free to work from wherever you please. You can also choose to work from our office in Porto or Barcelona, or we'll get you a dedicated desk at a co-working office near you. :)

To learn more about who we are and how we work, please check out our Ambition & Balance blog: https://blog.doist.com/
Because we have cars
What’s a Facebook shadow profile
Accidental contact probably happened a lot. Those are the stories that would be fascinating, but we'll never know about them. Planned colonization and/or trading missions are the more dubious claims.
You're very kind, thank you so much.
I put disposable income into a few ICOs where the ideas are amazing and the team looks capable of implementing it. It's like a kickstarter to me. Might not work, but if it does I get something cool. Like if SNM works I effectively get access to really cheap compute power.

So no, they don't work yet... which is why they need the money to build the product.
Of course they did, where else could the gyros have come from.