skysight-inc/HackerNews huggingface dataset:
> Suppose this wasn't the case. The news headlines would of course be "Experimental drugs being tested on minorities". That would be a PR disaster.

Interesting. When you say suppose "this" wasn't the case, what do you mean by "this?" Do you mean the neglecting minorities in medical research leading to numerous negative consequences?

From what I understand correctly, you are trying to state the negation of OP's headline. If so, it's unclear how you arrived at that specific headline. Can you walk me through your line of reasoning?

> Essentially, the drug companies can't win. People will find something to complain about.

That's quite a bleak forecast. Can you clarify what it means for drug companies to win?

From my frame of reference, the game is the political arena, and a participant (or political entity) is "winning" if they can ensure they're interests and concerns are considered and upheld. Between 1998 and 2017, Pharmaceutical/Health product industry spent 3.7 billion dollars lobbying on capitol hill [0]. Interestingly, this was the highest amount spent by any industry. Moreover, it was 1.2 billion dollars more than the next highest industry, the insurance industry. If we examine just 2016 (and 2015), we see that Pharmaceutical Research & Manufacturers of America (PRMA) spent 19 million on lobbying [1], up about 1 million from the prior year. PRMA represents companies in the pharmaceutical industry, i.e. Big Pharma.
It was surpassed in spending by the Blue Cross, American Hospital Association, Chamber of Commerce, and National Association of Realtors.

Further down that list, we see Pfizer chipped in 9.7 million (up from 7 million in 2015), and the Biotechnology innovation organization chipped 9.2 million (up from 8.3 million in 2015).

At least to me, this doesn't seem like the behavior of someone that is eliminated from a competition. If things weren't going right, I would likely cut losses and try alternative routes, not spend more. So it suggests they are satisfied with the influence they're dollar buys. Presumably, they are able to clearly communicate their interests and concerns to the decision makers on Capitol Hill. Moreover, they are able to communicate these interests and concerns _behind closed doors_ to receptive members of _both parties._

Perhaps my thinking is faulty, but to me, it seems like they're winning, i.e. influencing policy in their favor.

> Either minorities are getting neglected, or they are being abused as lab subjects.

Can you explain why these are the only two options?

[0] https://www.opensecrets.org/lobby/top.php?indexType=i

[1] http://thehill.com/business-a-lobbying/business-a-lobbying/3...
As I recall, the only way to group taskbar icons in 7 requires you to also display window titles in the taskbar, which is endlessly annoying; the way to work around this is to enable grouped icons/window titles and then edit your registry to impose a max pixel width on taskbar buttons so that the titles are unseen.
This is welcomed news, thank you for the update. Can you link to v2? On the site I just see part 1, v1 with the AWS set up. This is the beginner unfriendly/outdated one I am referring to, and I don't see the updated version you're referring to.
So now you are shifting the argument to a market information problem to a market irrationality problem. Typical.
Often, first author is considered the primary contributor, while last author might be considered a principal or adviser. By adding a disclaimer and listing authors alphabetically, you can try and dispel that misconception if this isn't the case for your paper.
Typically most credit goes to first and last author. However, there are cases where one person needs to be first author, but multiple people are equally deserving.
> Historically I don't think so.

WWII was a great leveling of the playing field. There are many times in history when Gini coefficients dropped precipitously. All the evidence points to the fact that wealth tends to accumulate in capitalist economies until crises or government intervention prevents it.
Yeah they would never say that out loud that guy is full of shit
>You can make a straightforward pencil manually with a little effort.

Step 1: Find a graphite mine.

Making anything without the benefit of the market is staggeringly difficult. Knitting a sweater is easy. Raising your own sheep, shearing your own wool, washing, picking, carding, roving and spinning your own yarn is immensely difficult.
the term "trickle down economics" is to the right as "political correctness" is to the left. both terms were created as strawmen to smear the other side's position.
You could switch to TempleOS. :-)

Meltdown is a much smaller (but not zero [1]) security risk on TempleOS than it is on Windows or Unix and Unix-like systems.

[1] At first one might think there is no risk, because TempleOS runs everything at ring 0 in a single address space so anything that might be exposed via Meltdown is already wide open. That would be true in the case of running untrusted binaries. Where Meltdown would still affect TempleOS is in in the case of trusted binaries being exploited via techniques such as return oriented programming. Meltdown could make more "gadgets" available in the binary, increasing the chances that someone could make it read something it otherwise would not have read.
This. I was playing Starcraft before bed, and just shut my laptop to suspend it... it was suspended until about 4 hours later, when, in the middle of the night my wife and I were awoken by sounds of zerglings dying. Very unpleasant, and quite surprising.
"Cultivate friendships"
>>>
The secret is you have to leave your house and be at the same place routinely

example: get a dog, go to dog-park at the same time every day.

"The Great Good Place" teaches us that in order for a space to be social it needs to be in walking distance and cheap enough to go there every day, examples French Bistro, German Beergarden, American greasy diner, Coffeehouse. Depending on where you live you might not have access to such a place, consider moving close to one.

The military teaches us that friendships are forged in suffering, so do some group fitness bootcampy thing, like crossfit or similar.

To get love, give love. Volunteer your time in some fashion.

We are social creatures.
https://www.cnbc.com/2017/11/09/gary-cohn-trickle-down-is-go...

"And we see the whole trickle-down through the economy, and that's good for the economy."

That's Gary Cohn, the chief economic advisor for Donald Trump.
The Reality of Color Is Perception
The problem is religion. That's why there's too many people (birth control is evil and God doesn't want it, etc.), and that's why they have a lazy culture.
Why should we try to change them into a consumer economy?

I read the article but the problem was identified near the beginning.

The top 1% of Indian adults, a rich enclave of 8m inhabitants making at least $20,000 a year...
World Bank Unfairly Influenced Its Own Competitiveness Rankings
The holding cell is actually worse in some cases. Here, it’s a concrete box that you can’t leave until you go to court or get transferred to jail. You get shit for food, banana for breakfast, pbj for lunch, etc. At least at the local jail, you get rec time, TV, and subjectively better meals. I caught a 4 day weekend in a holding cell with 3 of them without anther person. That really starts to eat away at you as it’s essentially short term solitary confinement.

Just to add, that’s 3 days solitary for not even being convicted of shoplifting. The charge was dropped for other reasons.
Because it's less expensive. And it isn't exposed to forward price volatility of fuel.
Is there the possibility of adopting this with an explicit caveat that the details are subject to change? I would have found it incredibly useful when first learning about these types; feels like a missed opportunity.
FWIW, the Dead and Caspian seas are actually dismembered bits of ocean. They're salty because their water was originally salty. The only salty lake I can think of that didn't begin with ocean water is the Great Salt Lake, which is an evaporated basin from a much larger lake that just happened to sit on salty bedrock.
I think it's really more of a class marker than a "Western" thing.

Eating out is certainly the default choice for professionals in New York, London, Moscow, Dubai, Singapore, San Francisco, or Hong Kong.
I am not moralistic, it's just different. Economically also it does make sense when you consider all the waste these restaurant produces competing with each other and catering to visited taste. They have to over stock or cook and then waste it when it goes unsold. All that cost gets transferred to person who buys so I don't think it comes cheap. It does save time though.
I'm a frequent sleeper and I depend on the feature. Next time your machine wakes up by itself, go to a DOS prompt and type "powercfg -lastwake" That will tell you how it happened.

For me, part of the solution was to go into the device manager and edit the properties for my mouse and my network controller. On the "power management" tab I disabled the "allow this device to wake up the computer" option. I only use the keyboard to wake the PC.

Additionally, when I left the machine sleeping overnight, there was some scheduled task that would occasionally wake the machine. There is a way to disable that, but I forget the specifics.
I intend to hook that up to a USB adapter and try it on a Linux box. I'll post a writeup if I get it working.
isn't it pretty hard by now, BTW? Look at all these negative return rates in huge banks.
> dangerous (disabling Google Safe Browsing)

Dangerous is a strong word here. Yes, this feature does make browsing the web safer, but I would stop short of inverting that statement to mean that disabling it makes the web dangerous. It primarily protects you from sites engaging in social engineering of some kind: these can admittedly be extremely sophisticated, to the point of fooling most very technical people, but generally speaking it's still mostly avoidable with some care.

I would recommend most people having a safe browsing feature enabled, but I wouldn't fear-monger those disabling it either.

It's also worth mentioning that Mozilla provide their own service here -- Shavar -- so one needn't use Goog
Is the mechanism of 'Arc' gene related to the dynamic routing process of Capsule networks [1, 2]?

[1] https://kndrck.co/posts/capsule_networks_explained/

[2] https://arxiv.org/abs/1710.09829
So, "high evidence" is some intelligence guys assuring it is so. Because they don't lie. And people should just take their word, because, as they say "there is no magical way where you can both show the evidence and protect sources and methods".

Sounds really solid.
We can call it Apollo 50. Are you on board?
You are making the articles point Indians don't have the disposable income to spend on Starbucks which becomes a luxury.
I just checked the course forum, and Jeremy asked us not to share on high traffic sites until theyve finished the new website. I think it'll be out within a week or so, so check the fast.ai site for updates. Should be soon!
On Open Source
Ask HN: Where are the hacker zines and websites?
In true 80's and 90's fashion. Is there anything out there these days?
>Don't go crazy trying to figure out its secret meaning.

There's no "secret meaning", and it doesn't refer to spatial dimensions. It has a very clear and very precise mathematical meaning.
The actual paper is paywalled. Can anyone tell what the sample size of the stud(ies) was?
Too religious. China's great advantage is that they're all atheists.

Highly religious societies have a strong desire for tradition, and tradition is "women don't work and have no power, corruption is rampant, new things are bad (because they destroy the golden geese that keep the upper class rich and in power)". Pakistan and India are going nowhere soon.
I have a hate/love relationship with JavaScript.

Also have similar background in programming languages, plus a few more given my interest in programming language research.

What I can't stand is seeing projects with npm, grunt, yeoman, webpacker altogether.

Thankfully I am spending most of my time in other eco-systems and can still do Vanilla JS projects.
A rich person would have most of their assets invested, existing in the form of factory equipment, buildingsin active use, truck fleets, etc. That is, pretty much moving.
Not true. The fascination with Brahmin has been replaced with the Rich quite a while back. Not saying that there is no cast discrimination in India, there is. But being born Brahmin is not as big an advantage today as it was in the past. Being born rich however is a different story.
"The state of education is appalling."

"They need only 1 or 2 more generations to truly rival or even surpass China."

These two seem to be in contrast. Do you know what is being done to change education for most people that would radically improve outcomes within 1 generation or 2?
If you use a modern SaaS account app like Xero you can already access banking records no? What does this give us that you don't already have to fully automate your business?
A small subset of Indians will probably continue to prosper.
Can't tell for other countries, but most of those that are still triving in Poland after system change are subsided by local goverments.
If you cook a full meal seven nights a week, where ever meal is different, and cooked with quality ingredients, it absolutely can be more expensive.

Though, if you actually plan your menu, or plan dishes that can carry over to two or three nights, cooking is far cheaper.
I was coming at it more from a "having alternatives is good" comment instead of saying it's not vulnerable to the new problems. The specs look interesting enough to benchmark on, and perhaps if it actually does perform better, then even with patches it will stand out.
In addition to the reasons already posted, here's another: tuning mRNA degradation rates is something cells are already very good at. If tuning the effective communication distance is desirable, using mRNA would provide a ready-made set of tools to achieve it.
This is pretty cool. A PC with an 80186 CPU is a little weird, though; I don't think many of those actually existed. It seems like virtually everybody went straight from 8086 to 80286
I still get by, by just putting whatever I need into the scripts folder and then using ASP.NET bundling APIs.

Similar approach on the Java projects, a scripts folder under the webapp resources.

It might be old fashion, but keeps me sane.
From the article: "The biggest responsibility of a founder is making the right decisions."

No shit?
Wouldn't raising their salaries and improving job security be an easy fix?

Or perhaps, why would that be hard?
fast.ai Making neural nets uncool again. fast.ai is dedicated to making the power of deep learning accessible to all.[0]

Udacity. Intro to Machine Learning: Pattern Recognition for Fun and Profit[1]

MIT 6.S099: Artificial General Intelligence[2]

Lecture Series on Artificial Intelligence by Prof. P. Dasgupta, Department of Computer Science & Engineering, Indian Institute of Technology, Kharagpur[3]

DeepMind. Reinforcement Learning Course by David Silver[4]

Stanford Winter Quarter 2016 class: CS231n: Convolutional Neural Networks for Visual Recognition.[5]

[0] http://www.fast.ai/

[1] https://eu.udacity.com/course/intro-to-machine-learning--ud1...

[2] https://agi.mit.edu/

[3] https://www.youtube.com/watch?v=eLbMPyrw4rw&list=PL6EE0CD029...

[4] https://www.youtube.com/watch?v=2pWv7GOvuf0&list=PL7-jPKtc4r...

[5] https://www.youtube.com/watch?v=NfnWJUyUJYU&list=PLkt2uSq6rB...
In any sufficiently large corporation, there are so many different accounts/credentials floating around, that it's hard for anyone to keep track of them all. It's possible that the engineering team may have already invalidated the credentials that were published on GitHub. It's possible that those credentials were actually a bait, meant specifically to distract potential hackers. Asking for proof is a very quick and easy (and sloppy) way to get around all of the above.
The horrible thing about generalizations is that they are so painstakingly accurate sometimes, and they hit so close to home that people hate them. Americans are hilariously uncultured. Do software engineers tend to be socially awkward? Yes. Try to understand the world for what it is or live in perpetual cognitive dissonance, your choice.
>You can make a straightforward pencil manually

You're inadvertently moving the goal posts. A "straightforward pencil" isn't what that 1958 essay is about. It's talking about the modern manufactured pencils[1] commonly used in schools.

It's very unlikely that a single person on Earth knows how to make such pencils from raw materials. The person who knows where to find graphite and how to mine for it will not be the same person who knows how to formulate the paint. Neither of them knows how to chop down raw trees and make small hexagon shaped tubes to hold the pencil lead. Then there's the steel or brass ring coupling the eraser to the the wood. There's also the chemistry and materials science to make the synthetic rubber for the eraser. No single person on the planet knows how to make that type of pencil.

[1] https://www.google.com/search?q=no+2+school+pencil&source=ln...
Er, style guides deal a lot with aesthetics. That's kind of the subject matter at hand.

I think it's silly to add another rule to remember with such a weak justification.
A Brief History of the Big Dumb Object Story in Science Fiction
Okay, I will check in a week or so. Thanks.
There is no 'birth control is evil' concept in Hinduism. 80% Indians are Hindus. Poverty is the reason for there being too many people. Poor people tend to have more children.
EasyWorship 7 Crack (Beta) and Product Key Free Download
Technically, you pay for both time (hours on) and CPU Usage (instance tier). Its not like different instance tiers (at least in the same class) use fundamentally more or less powerful processors. They all use the same processors, you just get more or less of it depending on what you pay.

Conceptually it is "pay as you use" by CPU usage, but just rounded into buckets by instance tier.

Of course, there's a lot of underutilization within each bucket, because the granularity isn't per 1% used, but (more or less) per 100% used (aka each core). And also, most applications can't switch instance tiers easily to adapt to demand (though some certainly can).
My initial guess would be to align pricing with expected performance, which has now degraded, right? I don’t expect it to happen, but I can see customers like myself being unhappy with paying—just for example—for an 8-core VPS whose performance now matches what previously was 4-core performance. So, I don’t think anyone would expect them to charge less for a higher core count than lower core count, but adjusting prices downward to match performance wouldn’t be upsetting.
Less expensive to some. But heavily subsidised by the taxpayer
How much do you think such an OS could be sold for?

For me, Windows wastes about 2% of my time per year (mostly due to Windows update). From a business perspective, that might justify a $10k expense to recover that lost productivity. From a personal perspective, I would pay $500 to recover that time for my own use. No idea if there's enough like-minded people to make a new OS profitable, though.

The sticking point is that to recoup time lost to Windows the new OS would have to completely replace Windows, which means being able to run key Windows-only business software (SolidWorks, etc.). Maybe it makes more sense to just support Wine instead of reinventing the OS.
MIT 6.034 Artificial Intelligence, Fall 2010

https://www.youtube.com/watch?v=TjZBTDzGeGg&list=PLUl4u3cNGP...
Yeah, I don't recall having seen 80186 on sale.
I’m not lpolovets but I do angel invest and my take is the math really does only make sense if you get a few big hits... which would imply the only rational angel/VC strategy is only invest in ones with big potential (and diversify). And that’s what I try and do.

That said, I have seen that a lot of small seed funds and new angel investors (most are new!) like to say that they’re happy with lots of small wins. I dunno if it’s just their way to show how they “think different” from the conventional wisdom (of “go big or go home”), or it’s just to seem more down to earth and approachable to not turn off potential deal flow, or just because they are really new and haven’t actually done the math (or are more risk-adverse than they probably should be in this line of work).

But then, when push comes to shove, I haven’t seen any ACTUALLY invest when they honestly don’t believe it could be a $100M+ exit.
tried fast.ai?
http://news.berkeley.edu/2011/09/22/brain-movies/
Welcome to the Coherence Economy
I can see this going a couple different ways, but by far the most interesting scenario I feel is the one where countries that don't pass the smell test start floating to the top.

If all of the sudden, countries that have been driving their economies off the road, like the Venezuelas of the world, float higher in the rankings, can we put more nails in the World Bank's coffin? They give advice with disastrous consequences for impoverished countries.

I think it was Reagan advisor Jude Wanniski who used to refer to it as the Destroyer of Worlds Bank.
This headline is such clickbait. Netting out all fossil fuels is silly. Natural gas is alive and well and growing quite quickly, while coal is suffering.
RM had a 186 based system, but the reason for 186 is that it's a relatively small delta over the 8086 vs 286!
no more than coal or oil.
" . . . forward price volatility of fuel."

This is more important to most companies than cheapest price. It enables them to plan with more certainty.
Pretty cool as a design like this should be able to better preserve old system behavior than what DOSBox etc. can achieve.

Although it seems a bit slow side at 50 MHz, I guess it's not a pipelined design?

Not that original 80186 was pipelined either. :)
E-inks are fundamentally analog, so theoretically you could have as many shades of gray as your timing resolution allows, but basically all the commercial controllers available abstract the display as a dumb framebuffer so you can't really access their fundamental operation of "make this pixel slightly whiter or darker.
That's scrote (long O), not scrot (short O).
https://www.thekitchn.com/search?q=Cooking+Lessons+from+The+...

There you go. No need to buy any more cookbooks.
Yes, I've heard of them and others, but I think dboreham already put the matter conclusively at rest:

https://news.ycombinator.com/item?id=16138402
Guess the kyoto group are competing w/ Jack Gallant's lab...

btw, pycortex from his lab is out on GitHub...neat to play around w/ if you have the fMRI data
It has the same word in it, that's about it. Come on, use your brain a bit
iOS 11 Security [pdf]
Tag based permission system AKA SELinux. Tried, tested, determined to be superfluous bullshit whose only protection is in the jobs it saves at the NSA required to maintain any sort of SELinux ruleset.
I'm holding one in my hand right now; the HP200.

There were others:

https://en.m.wikipedia.org/wiki/Intel_80186#In_personal_comp...
Probably a security hole
It seems a bit unfair to blame the language for the added complexity that is introduced when debugging a browser script. Pycharm (or any of the JetBrains IDEs with JS support) offer a very comparable debugging experience for server side Javascript.
The rapid rise of Seattle: Time-lapse video captures city’s massive growth
Pulling out is specifically prohibited in the Bible. So is oral sex. But nobody gives a shit. The funny thing about religion is that there's so much nonsense in their official texts that you can make it mean whatever you want :)
Funk, soul, and hip-hop make me happy. Turn off rock: it is derivative and depressing. So called alt-rock should be crushed under a, uh, rock. Jazz is great, but not full of joy, as is classical music. Folk has the same issues as rock plus an insufferable homogeneity.