skysight-inc/HackerNews huggingface dataset:
Ideally the drug company making this thing would just stop being boneheads about pricing.

I think this is silly. We don't expect that companies "stop being boneheads" (by which I assume you mean act more ethically) when it comes to the pricing of televisions, or food, or household goods, or practically anything else. Why should we expect it for these pills? That expectation will be doomed to failure in many instances.

A more ideal scenario would be to examine the underlying reasons that allow the company to charge so much for something that apparently costs so little to make. If we can understand that problem we should be able to implement fixes that lead to proper pricing without the expectation that profit seeking corporations will magically decide to forgo profit just to be nice.
There's no cartel pricing in medicine. If there was there would be a competing cartel as it is the case everywhere.

The reality is that companies that make generics are simply too small to be able to compete with Pfizer, Merc, Glaxo etc and for all big talk our scientists in R&D and FDA are bought and sold like trading cards and their opinions change with the opinions of their owners, which is, for example, why FDA accepts garbage studies from Pfizer and does not from itty bitty company that competes with it.
I'd noticed that Intel's recent foundry wins were confusing me but with that relaxed process they make much more sense.
As `naiyt` said, try audio books. I used to feel the same way as you and then bought a bluetooth receiver that fit into the back of my car stereo and now listen to audiobooks during my morning/afternoon commute. In 2 years I've probably listened to 40/50 books.
You're obviously closer to the issue than myself and I'm truly glad you moved on to create something new and different with Brave. I didn't follow the issue entirely closely, but it seems that there were quite a few more than six people in the company that were upset about your monetary contributions. Realistically, you have to know that saying it was just six people that were upset about your monetary contribution is hyperbole.

My comment doesn't just pertain to you nor did I really dig into the merits of your situation, but it does serve as a valid test case that even someone with your obvious and deep technical skills requires more than just those skills to be in alignment with what the company needs from a leader.
Virgin Trains at least are nice and if you book well in advance very reasonable deals are to be had. We paid ~42 quid from London to Manchester in first class, one way. Alas we bought the tickets month' in advance and, of course, non-refundable.

For shits and giggles I tried to figure out what the same ride costs like when you buy the ticket 30 minutes in advance. And there we come to 280£ each, which is completely ridiculous. It's not that good (2nd ist still ~90quid)

Now, don't get me started on Northern. Filthy, Expensive, Clueless and slathered with a heavy dose of disorganisation.

I think you can honestly say that privatizing trains in the UK was an experiment going horribly wrong.
NiO is a shortcut in german for Nicht in Ordnung, which in factorys denotes parts that are not okay. Is this a insider gag?
Sure, but bear in mind class action lawsuits are fairly specific to the USA. Mandatory arbitration clauses are less useful outside the USA because people are less likely to sue to begin with, and cannot sue as a group.

There may at some point be a huge negative event as you describe. I'm not sure there extremely rare events should be used as the basis for sweeping regulations. That has not worked out well in the past.
Show HN: Golang-only eBPF library
Miserable Travelers Stranded After America's Busiest Airport Lost Power
What an absurd statement.

Do you use a laptop? I do and I'm using swap space right now. I would like to buy a laptop with 32 or 64 Gigs of RAM but I can't as most(all?) laptop makers don't ship with a memory controller that permits more than 16 Gigs of RAM. And I can afford to buy more RAM.
Instant literature suggestions while you type your research paper
Being a capitalist is not defined as a love of obtaining capital. It's more than that: it includes a belief in markets and a dislike of government intervention, which can of course be intervention to prop up his competitors.
Bitcoin Takes Bigger Wall Street Stage with Smooth CME Debut
Self-healing glass discovered by accident
On Lessons the Common Lisp Community Could Learn
Who cares, it's another car for 6 figure earners. Seriously how many here on hackers news can afford to spend ~120k on a car? ...my car cost the rounding error of that number.
To my eye, it looks more like an SUV than the X does.
> Site is working now!

…aand it's down again. Seems someone or something just increased that "daily limit" from 1000 to 2000 MB …
The venom in your TLDR makes it hard to be enthusiastic about reading the rest of what you have to say.
SME Announces FIPS 140-2 U.S. Federal Government Validation
I find this ironic, given that as a long-term Mac user, I bought my first ever Windows machine in the process of becoming a self-taught programmer. Turns out there's quite a lot of demand out there for those able and willing to develop on Microsoft platforms.
Personally, because the video autoplays disruptive sounds, I'd rather have the link to the paper with a link to the video as a comment.
Landwind X7 have 90% look of Land Rover Evoque though. It would probably have crapy engine, interior ..,, but my point is that chinese cars are definitely improving.
That's what make has been doing for the last like 40 years.
I used to work in flash manufacturing. We would joke, "I hope nobody ever uses this for swap!" The numbers I saw for endurance (basically write-erase cycles before failure) were not encouraging at all. As far as I can tell the only reason MLC flash works at all is that the controller does some magic to present a whole bunch of pretty flaky cells as a single reliable unit.
> their efforts are often ineffective or outright counter-productive to their stated goals.

The fact that the employees complain doesn't mean that the money they invest isn't effective for the goals they have: to increase doubt in the facts that they don't like and therefore prevent or even just slow down possible actions against their interests.

Then, what is the support for your claim that they are ineffective?
So, wouldn't the best answer clearly be to buy even more RAM, and use a RAMdisk for swap?
Farewell to the 747, the Plane That Shrank the World
I'm not sure your conclusion follows from the article. The lack of controls may contribute but the reasoning may have not been greed. There are many market factors in play. It may very well be greed but I don't see much evidence in this article either way.

In other words, the article explains why the price growth was not capped. It does not explain why it grew in the first place.

In general I wish the drug company had taken time to contribute to this article and show their side of the story.
I think the industrial world is definitely more formal (corporate?) with good reasons. It's extremely hard to sustain a certain profit or product without a proper organization. Engineering in the industrial world is definitely less exciting since there's a lot of red tape. Convincing the department I work for to spend around $10K for a couple 3D printers took forever. Where when I was at the startup it was more of a "why not" mentality as long we had funding. However, the benefit for working in the industry is that there is a lot less circle jerking on the engineering side of things. When you're working at a startup, there is so much circle jerking and smoky mirrors to get funding and please investors. I sat in during a board of directors meeting and I physically wanted to puke listening to all the BS going around in the room.
The Pessimist's Guide to 2018
Safety might be a good reason to prohibit imports from a place like Tanzania, but it makes no sense as a reason to prohibit imports from Canada. Canada has some equivalent to the FDA which is about as good as ours, so there should be no safety problem when it comes to importing their medicine.
Are there structural problems with this approach or is it mainly because of immaturity? Usually version 3 of most software is mature enough to judge it by its merits.
In an ideal world poor quality publications regardless of audience size would end up being penalized for poor quality reporting. Sadly, the world is not ideal and markets at best an approximation of efficient markets.

CNBC is prime example of this for me. Nowhere is it more apparent that in Jim Cramer. The hyped-up advice he gives people on investing is terrible. It's worth while watching his interview with John Stewart when they talked about the housing bubble. The whole sorry, not sorry squirm. But this is just the tip of the iceberg for CNBC.

To me the important question is: can we engineer (not just software) a solution that does rewards good journalism and punishes bad journalism?
One where ACA did other things besides just raising the number of insured people?
I doubt you can read that much into it, any org that excludes INTJ's is going to find hiring programmers quite hard.
Swap engineering is definitely way more complicated than the article lets on.

What people often don't realise is that Linux distinguishes between dirty and clean memory, with dirty memory not reflected in swap, and clean memory already stored somewhere on disc, and program code is counted as clean memory that just happens to live somewhere other than swap.

Therefore, under memory pressure (especially if you set swappiness to zero), you will be preferentially swapping out your program code (because it is always clean) in preference to your program data. If you have no swap, then this is what causes the system to grind to a halt when the RAM is full- all your program code gets discarded from RAM, and nothing can run without reading it from disc again.

The recommendation to have a little bit of swap is absolutely fine. However, as the amount of RAM in your system increases, the penalty for running out of RAM increases as well. On larger systems (for example 256GB RAM), I recommend using something like EarlyOOM[1] to kill off tasks before the pathological swapping case occurs. Otherwise, you could end up with an unresponsive system. If you have lots of RAM, the kernel OOM killer waits far too late, and the system is already unresponsive.

[1] https://github.com/rfjakob/earlyoom
Because American healthcare is, from an outside perspective, utterly insane.
Maybe the market in the US isn't big enough to recover the fixed costs. How many pills at 4 cents would they have to sell?
So, `make -j`?
Well Microsoft has msn messenger and shut it down, not there are WhatsApp, telegram and many others but I'd pay good money to have msn messenger back
The Mess with Ajit Pai, Harlem Shake and Copyright Is Bad and Everyone's Wrong
Separately be sensitive to cultural issues as I don't know where you are developing. In my professional resume editing business based in Shanghai, I wanted to set up a really polished resume site where employers could screen my clients since they've been through my full process (resume, LinkdedIn Profile enhancement, interview coaching) and a top notch candidate. I found people are afraid of their stuff being too accessible in public due to being targeted by criminals and ID theft. It's a damn shame really. Good luck!

Vince Fulco, CFA, CAIA
vfulco[@]weisisheng.cn
Technology Business Review Newsletter: Fox,Snapchat, Suspicious Traffic Activity
Show HN: First security bounty with Google:Knowing who is interviewing with them
Déjà Vu All Over Again – Russian Active Measures
I think there's too much synergy to be had by having the process engineers work closely with the architects when deciding on the design rules.
In the spirit of learning about these things, you might want to try these: https://cryptopals.com/

In particular, problem number 17 from set 3 is an attack against CBC mode AES used with Mac-the-Encrypt. Maybe a fun exercise would be to first implement that attack against CBC mode, and then try to see if you can make it work against your CFB-HMAC protocol.
I think the Koch brothers are more active and problematic than the other side's boogeyman, George Soros.
Plus immutability, plus message passing paradigm (and the associated distribution).

The immutability prevents entire classes of bugs, and helps enforce predictability on the part of your code. It also is assumed at least in part when it comes to message passing (else, what happens if you change a referenced binary after passing it in a message? Does the message change too, or remain static? Either way, complexity)

The message passing paradigm for interprocess communication ensures that the developer is forced to ask "What happens if this isn't received", i.e., if the process is down or missing or etc. Any sort of 'return', via a message sent back, could not happen; this is akin to a called function throwing, which again, requires the developer to ask 'what happens if we never get this response back'? The answer is never to wait indefinitely, it's to...what? Other languages make it very easy to ignore possible exceptions; in Erlang, not only are they likely handled (if you have your supervisor structure in place), but you're forced to decide how such a thing in another process affects the current process (if at all).

Because of the message passing paradigm, the distribution story is simplified; it's largely transparent as to whether the process you're sending a message to is local, or remote. This allows you to build in redundancy across nodes without many of the complexities (and thus, room for errors) that other languages give you, nor the lying abstractions many languages give you (such as RMI).

And having the distribution Erlang does helps with the reliability side of things, as it makes it comparatively straightforward (still complex, but far less so than most other languages) to get solid handling in the event of machine failure.
You can indeed cash out Bitcoin and the number is reasonably accurate... up to a certain amount. $100? Sure. $1000? Yeah. $10k? That's alright too. $100k and upwards is when your order might actually start having an effect on your exchange to shift the price upwards or downwards.
From the article: "In the years following albendazole's price hike in 2011, Medicaid spending on the drug went from under $100,000 in 2008 to more than $7.5 million in 2013." To most Congressional Republicans, this is beautiful music begause it means one of their constituents is getting rich by ripping off taxpayers. (Indeed, it may be the only form of music they can appreciate.)
How to Build a Mobile App with React Native Components
What is the point? I type in "thirteen" and get back NUMBER:thirteen. If I got back 13 it would be useful, but just identifying that it is a number is ho hum.
You haven't saved time compared to using a query builder though; in fact you've lost time due to the hit to readability and debugability.
Even if they succeed in building a Tesla worthy competitor, there is still the huge issue of battery production. Tesla will lead the coming years not for its nice car implementation but rather its production capacity of cheap high quality batteries. I wonder how China will bring that production capacity.
More dead commenters appear to come out against Net Neutrality
It's actually ( 12864852000 * 20 ) possible board combinations. Not quite trillions; more like a quarter of a trillion.
They make one to seal the pot that goes in the fridge, too. I don't think it is used for cooking at all. I havn't bought one yet, but it is on my list.
Is this legal in your country?
That's not entirely true - individual addresses and/or transactions can be seen as "tainted", and those coins can be tracked through the Blockchain.

I've been a Bitcoin proponent for a long time, but this lack of basic fungibility is one of its major downsides in my opinion.
McDonald's can have 24/7 drive though windows while selling burgers and fries, but most pharmacy's are not open close to 24/7.
Yes, it definitely could be this which is why I said "my gut suspects the arduous FDA approval process." This could be the source of a lot of that fixed cost. I'd be generally curious to see data on what is involved in starting up a new production line for these kinds of pills.

Is there a chemist in the house? :)
Idk, my grandma has a similar unit she got a couple decades ago. It was cheap though I don't know how cheap. (I do know my grandma though.) Lots of competition that's similarly priced.

The main benefit of the stovetop units (I have both) is speed. The heating element on the cheaper electric is drastically underpowered and can't even get a good Mailliard. The higher end ones can but they're still much slower than a gas stove, especially when full of liquid. I pretty much go back and forth between the two based on what I am cooking.
Loud Objects (Tristan Perich, Kunal Gupta, Katie Shima) – Noise Toy
People run into the same wall dealing with support for any company.
Sold by the same corporate entity that produced the vehicles branded as SAAB, albeit under a new owner.
That's not what I've said. And I'm not suggesting this. Your comment is a bit hostile.
The company typically outsources the actual manufacturing of the pill, as well as the packaging and shipping. Those are real costs.

The largest expenses are marketing and sales. Doctors won't prescribe drugs they don't know exist, so "educating" doctors about the benefits of a drug is a paramount. Contracts have to be negotiated with all insurance companies, and that's expensive too.

How profitable the business of generics actually is, we don't know for sure. The pharmaceutical industry is notoriously vague about how much profit they make, and the numbers they report are questionable. For instance they'll call market research into which drug to buy next "R&D".
GlaxoSmithKline produce Zentel[1] (manufactured in India), and they already operate in US[2].

1. https://www.unitedpharmacies-uk.md/Zentel-Albendazole-400mg-...

2. https://en.wikipedia.org/wiki/GlaxoSmithKline#Facilities
>> Is this leading up to some big news story to deflect news from something else?

No. The only way it could deflect from a really big story is if aliens actually came down and said "hi" publicly. It's got to be more subtle.
Sure. The problems the author mentioned with IOTA are definitely there. But as a developer, I just couldn't let that one slide.
Attention is often commanded by subject. It could be that with some people you're just talking about something boring, and with others you are literally the only source of information and people paid thousands of dollars to listen to you.

Basically, try talking about something the people you are talking to want to hear.
Does it offer encryption features like protonmail or tutanota? I had a free fastmail account for a very long time, but switched once they moved to a pay-only model.

Basically fastmail is ok, but not really worth paying for. The interface isn't revolutionary, but does its job. If you're happy with gmail or whatever web-client you're currently using, you're not missing much.
While your observation is interesting, it seems a bit silly to compare the operating expenses of a global media distributor to a local gym.
Professional gamblers price counter party risk into their bets as well. Using similar methods now that the bet takers are frequently public corporations.
These things you are talking about are usually called _voltage regulators_. DC/DC converter usually refers to the switching converter, they are very efficient.
I aslo live in Zurich and totally agree.

And yes, it's not exclusive to rich countries. I can also think of Prague, which has magnificent public transport with a subway rolling in every 90 seconds in peak time.

Buses and trams are less frequent (especially on weekends) but get you to just about everywhere you want to go.
No one is really really suggesting to burn it down. It is just an expression of how frustrated we are becoming with a system that is not working out. It is hurting us. It is hurting the country.
I think the biggest reason for this is because Silicon Valley has an abundance of younger workers (relatively speaking). When you're young, you spend literally every moment working to strive for your ambitions. When I got older, I started to learn that every hour you spend at work is one less hour for you to spend on something meaningful to your personal life. At the end of the day, working long hours is just not worth it. There's literally nothing to show for it at the end of the day. You make less per hour. Your family hates you. And you have no personal life. The only people that really benefit from this mentality is the owners and investors and this is so unfair and toxic to the workers.
* Medicare will pay for it
"Do people really believe that infrastructure is not the purview of the government?"

I don't think anyone is arguing that the government shouldn't be responsible for certain infrastructure, it's the degree to which the government should be involved, and what its role should be. If I put on my more conservative hat for a minute to make an argument, I think the idea is that the government should be somewhat of a last resort for things, and that less is more when it comes to government involvement.

Part of the reason for that is that once the government is involved, it changes the incentive structure quite a bit. Using other infrastructure projects (e.g. roads, bridges, etc) for examples that others have pointed out, they're a great way to raise taxes earmarked for those projects, but then that's when politicians start to play games and move money around to their own projects, and now the roads are falling apart, so we need to raise taxes to pay for the roads!

It's also somewhat tricky because once something is a government project, it's basically that forever. It's fairly rare for something to go back to the private sector once it has become a government program. What is more likely is that the solution is more government involvement, and that's something that conservatives tend to view as a bad thing.

Obviously I'm not speaking for all conservatives, and this isn't even necessarily my own viewpoint, but I wanted to push back against the idea that "conservatives just want what's worst".
Do you think the Model 3 competes with the BMW 3 Series/Audi A4?
I've swapped hundreds of terabytes to consumer SSDs. Haven't noticed any problems yet (visibly).
As I said, using a message queue like Rabbit MQ is basically the same thing. Granted you don't get a UI that is as fancy, but the promise that a task that is enqueued will be executed eventually can be given.
Yeah, I'd love to know if it was intentional.
I heard story, I don't it's think real (but imo funny) about China ordering foreign experts to build nuclear reactor. They had guys with binoculars watching those experts and building exactly same reactor over the hill.

Copycat^2
I guess the joke is that sharpening pencils is what you do when you have writer's block, so if you really have writer's block, you write a whole book on sharpening pencils?
Firstly, thanks for inspecting the source and offering a suggestion for improvement. The latter point should be a relatively easy fix.

As for your first point, there’s little we can do to prevent TLS or AWS tampering. But we can make it easier to choose e2e encryption in the first place. So we focused on reducing barriers to entry (no signup required, simple URL-based rooms) as well as providing these benefits over alternatives:

- Open source code

- Ephermeral message history (not persisted in a DB)

- Opt-out anonymity

We think these features make Darkwire a good solution for many users seeking secure, private online communication. Having said that, no solution is perfect and we hope to see contributions from the open source community to make it even better.