skysight-inc/HackerNews huggingface dataset:
3D pictures, like from MRIs, are big. You take a lot of them per patient. And it would be quite bad to use lossy compression on them.

From http://siim.org/?page=archiving_chapter2 :

> One example of the data generated for breast MRI can reveal the large number of sequences and significant amounts of data that are generated for what might be perceived as a “small” study. [...] A significant number of sequences and images result in an average of ~300 MB of data storage per study.
> Only if you believe software development is neither engineering nor science, and is purely creative.

It's certainly not a science, and it's very rarely engineering. About the
creativity, it's a craft. There is some creativity baked in, but about the
same amount as for mechanics or carpentry.
People killed in terrorist attacks in 2017: Europe vs. Africa
Most assuredly. But what are we talking about on a whiteboard? Not the things that I personally am interested in, or the things in my opinion most important to the success of a project.

Honestly the code review isn’t for the obvious rock stars. Anybody can pick them out. It’s for the sleepers who might not get a fair shake but who can deliver.
You can use ANPM, a web-based password generator algorithm. Just enter a platform name, a master key and a PIN and boum you obtain a brand new secure password.

It's free and you won't loose a minute again :-)

https://teddybear06.github.io/ANPM/
No. The users were not part of the conversation in which the researcher doxxed anyone. They were part of another conversation, in which his total involvement was a smiley in response to one of their tweets.

As the article makes plain: "Then, to subpoena a ton of info on 5 totally unrelated Twitter users... just because Shafer tweeted a smiley face emoticon at them?"
> There's a reason why there's so much fighting in this area. And it's not just oil.

Well, do share that non-oil reason you had in mind there!
Yeah, there could be a good idea there! Things have to happen at the cultural level too, but I'm all for experiments!
What many don't know: The exact chips and technology behind the Kinect v1 (as developed by PrimeSense) are still in use today in many products:

We (that is -- shameless plug -- my company DotProduct) combine a Primesense Carmine sensor (basically a smaller version of the Kinect) with an Android tablet and our software to create a self-contained portable 3D scanner (www.dotproduct3d.com).

Occipital has created their own version of the sensor which they call the "Structure" sensor, but it's still based on Kinect/PrimeSense tech (www.structure.io).

Matterport (a YC company) is using the tech in a tripod based scanner to create 3D interior walkthroughs (www.matterport.com).

The reason these sensors are still in use is largely that PrimeSense (at the time they released the Kinect) was technologically about 7 years ahead of every other 3D camera manufacturer in the market. Only very recently we're starting to see sensors that rival the Kinect/Carmine in terms of overall quality.
Maybe software development should be considered a trade?
A slightly more informative link, IMHO, is the article on medium.com[1], linked from this teaser/signup page.

TL;DR, I believe: They defined metrics[2], gather the relevant values from applicants and ask their algorithm: "How much?"

Buried in [1] is this gem:

In our pilot, we evaluated nearly 3,000 companies and committed to funding several dozen of those, across 12 countries and many sectors, without a single traditional venture pitch. In fact, in most cases the data-driven approach allowed us to reach conviction around an investment opportunity before we ever even spoke to the founders. Worth noting that when we recently looked at CEO demographics, we found that 42% were female and the majority nonwhite.

A purely data driven approach to VC investment could level the playing field a lot and I could imagine that adapting that concept to hiring is a) not too far off and b) a great way to reduce biases in the hiring process - if everything works as promised (or rather "as hinted at").

[1] https://medium.com/social-capital/capital-as-a-service-a-new...

[2] https://medium.com/swlh/diligence-at-social-capital-part-1-a...
We user both Slack and Screenhero at work. This is not a move I'm looking forward to. Slack's Video/Audio issues are so many that we also still use webex for person to person video chats more often than not. I've been nothing but disappointed every time I've tried to use slack for something that's not text based chatting.
But it allows them to do it at scale, which may or may not reveal itself a good bet. The good thing about their approach is that their scale is only limited by the amount of capital they have to invest. Say out of a 1000 investment based on their metrics, they average a 5% return. Then their model allows them to scale to make it potentially very profitable. Now of course that's assuming that with a larger scale they'd come out positive at all. If not, they'll soon waste all their capital and this will be the end of it :P
Run Apache Spark on the box with 256+ GB of RAM. The GC stalls by 60 or more seconds are quite typical for heavy queries.
I hope new GC will bring improvements.
If it’s semi automated with humans making decisions in the background it could make sense.

I guess the value it could bring is low friction yes/no without wasting the founders time.

It’s the time suck that is such a negative aspect of seeking capital!
Soundboks is hiring a front-end developer
Wait until Facebook gets into rental real estate.
That's like claiming that World of Warcraft is only 4MB because that's how big the launcher is. It also creates folders in the wrong place[0] (1 directory above %APPDATA%).

[0]https://i.imgur.com/FTZhjuX.png
> This assertion doesn't pass the smell test, unless you believe that the median working-age US household by income had a worse standard of living in 2013 than it did in 1973.

Actually you are the first one I see to dispute this. Do you base these smell tests/beliefs in any public data? I would like to see the source to have something to dispute this frequently stated claim.
So, without going into too much detail the use of crispr/cas9 in our studies is even simpler than driving protein mutagenesis. We have been exploring CRISPRi has a mechanism to inhibit key promoter repressors of our gene of interest. We've found that we can affect affect specific protein abundances by changing the rates of both RNA synthesis and protein degradation, based on the two cross-kingdom control mechanisms CRISPRi and the N-end rule for protein stability.
I agree, it is suspicious, though let's distinguish between hard science and soft sciences, and between observation and theory
So ask candidates questions. You really expect candidates to have work relevant to your interview to show? But you can ask how they deal with problems, cultural preferences, etc.
It was one event, a neutron star merger. The gravitational waves were emitted during the inspiral, the light was emitted as the neutron stars smashed into one another and then blew apart in a "kilonova". The two weren't emitted simultaneously, there was a slight delay between the production of gravitational waves and the peak brightness. However, the important aspect is that MOND theories predict not just a slight difference in travel times but literally months or years worth of delay.
There was a Star Trek (the original series) episode where some alien entity was manipulating Federation and Klingon forces to fight each other. In the middle of this, when the Klingon commander found out, he stopped fighting, saying "Klingons fight for their own reasons".

If the US wants to elect Trump, they can. If the UK wants to leave the EU, they can. But they should do it for their own reasons. Knowing who's manipulating you, and how, can help you make sure that you do it for your own reasons, even if you do the thing that someone else is trying to manipulate you into doing.
I always wonder what a better solution than capitalism is. It's not perfect, and it's pretty broken when politics and corporate interests are in bed together. However, we're seeing the ill effects of socialism (Venezuela) like starvation and I prefer the former. Furthermore, the crypto economy might be the closest example we have to "Free Market" capitalism.
I'm not from MT but I believe that is the correct interpretation, similiar to the laws surrounding California coastline

https://en.wikipedia.org/wiki/Montana_Stream_Access_Law
> But where is the news in this?

The existence of an interesting article is news enough.
Not sure why you are being downvoted. But I don't expect clinics in a country without something like HIPAA in place to be overly cautious about such things.
Looks like the EFF has to update their Reverse Engineering FAQ:
https://www.eff.org/issues/coders/reverse-engineering-faq#fa...
In French. The graphic is pretty clear, though. Europe is in blue; Africa is in red.
Although it is extremely unpopular I hold the opinion that it is possible that there may be genetic differences in intelligence (defined as the ability to succeed in a modern technological society) among human populations. Is it possible that by aiding poor nations (increasing birth rate, decreasing mortality) we are actually subsidizing stupidity in less fit subpopulations and decreasing the evolutionary fitness of the human species as whole? I don't know the answer, but scientific research into this question, unfettered by politically correct presuppositions would be interesting.
This kind of thinking will have to become more common again. Even if you have good reasons to keep it (which is always the first question), not everything needs to be available without delay or from everywhere.

On the other hand, the clinic in question has a big "follow us live in surgery & clinic" banner with Facebook, Twitter, YouTube, Instagram and Snapchat links on their home page...
I wish there was more Android One devices in North-America. Cheap, good, "stock Android" + garanteed updates.
If the landscape of VC's has changed so drastically that the only way to get a piece of the capital is by planning your exit strategy (to a tech giant) before you've done anything meaningful, then I do think Silicon Valley has changed for the worse (no, I did not literally mean it's dead).

Where did the unicorns go? All I see are the same ones that were here five years ago.
The other issue is that many companies juts have blanket bans against hiring a 'felon'; doesn't matter if it was murdering a family or stealing a TV
Trading Successfully with Moving Averages
Excellent work gchakr and seanhunt1! I love that you are thinking 3M big ;)

I'd also like to hear more about the CRISPR enzyme engineering process. How do you actually research, design, and manufacture at scale. And no, you don't have to divulge any secret sauce. Just point me to some open science resources ;)

If your modified enzyme based chemical manufacturing process is truly as revolutionary as it seems. Then I'd like to see your marketing reflect that. Think of a single cartoon image or logo design that can communicate to the public at a glance the idea that you are now using DNA to deliver 100X efficiencies in chemistry. Best of luck!

Living factories of the future

https://www.nature.com/nature/journal/v531/n7594/full/531401...
This is very similar to the dilema of drug manufacturers and generics to me. On one hand without a strong financial incentive you won't have big companies investing in the original pieces of software.

On the other hand at a certain point it becomes a monopoly with a negative societal impact.
True, but a paid short-term contract to do an actual task for the company would work. Knock out a small feature during the night/weekend. Keep it something contained and relatively straight-forward. If they can get it done, it demonstrates the candidate's ability to parse your codebase (so they are learning something they'd need for the job anyway) and they have contributed.

I think most companies just don't want to take the time to set this kind of thing up. Easier to just pass on people that won't do the requisite song and dance.
True, very good point I didn't consider. This is pretty common actually, as unfortunate as it is.
> You would think that without Patreon, nobody would be interested in their creations. I'm sorry but -wow-. You've got other ways to collect payments from people who support your work... and if you have a fanbase already, I'm not sure where the problem lies in moving off the platform.

I am going to go out on a limb here and guess that you are not a creator on Patreon...

Patreon kicking people off is a serious issue because Patreon works so much better than all of the competition, from Flattr to Gratipay to Paypal to Bitcoin. As it happens, I'm a creator on Patreon myself (https://www.patreon.com/gwern), at ~$600 a month. I wouldn't go homeless or anything if I was kicked off Patreon (thanks, Bitcoin), but it would hurt me a lot. When I started using Patreon in July 2015, it immediately roughly quadrupled my monthly earnings from donations as compared to anything I'd ever gotten from Flattr, Gratipay, Paypal, Google AdSense, or Amazon Affiliates, Bitcoin either with or without Coinbase (and much more than that comparing to May/June but that's a little unfair since they tended to be spiky). That is, incidentally, despite Patreon having net fees of 2-5x what the others do. And the total amount has since tripled.

I hardly even advertised it! (Heck, I hardly even advertise it now or provide any rewards or anything.) Now that is a network effect.

Could people have given me money other ways? Sure. Heck, some of my readers invented or worked at the payment methods in question, and were fully capable of it. And they did, a little. And yet, I finally get around to signing up for Patreon and boom. There were people who were willing to give me substantial amounts of money... but only via Patreon. They were set up for Patreon, and that made donating easy and convenient for them, and this makes all the difference in the world. One website, one account, one payment.

Saying Patreon has no real network effects or can easily be replicated or that being kicked off of it would be trivial is the strict contemporary equivalent of the HN discussion of Dropbox where everyone writes it off because 'you can simply rsync your files to your personal server'. It sounds reasonable; and yet it is profoundly wrong in every way that matters to real people.

Is being kicked off Patreon going to hurt those creators? Oh yes. Quite aside from the porn-specific issues with the alternatives, just leaving Patreon is costly - they'll be lucky if they can scratch together even half what they were getting before. Call that 'other ways' if you wish, but I say it's spinach and I say to hell with it.
> However, Facebook really is, at this point, a clear monopoly.

But here's a point: The zero-cost marginal cost characteristics of many software businesses makes this sector prone to be monopolistic. Acquire: data, users, or intellectual property and from there, competition will have little chance until a new wave washes clean the shores or you mismanage your company.

So the only way to stop this is to - do what? The political will and instinct, that would be required to redirect technological progress by not allowing monopolies is enormous. Not to mention the economical dynamics that come from companies competing on how to destroy privacy faster.
Yes, we are a representative democracy. I thought that was well understood.

https://en.wikipedia.org/wiki/Representative_democracy

As opposed to the form where voters vote on laws and policies directly:

https://en.wikipedia.org/wiki/Direct_democracy
Quora and Ethereum = Cent.co – Here are my thoughts
That doesn't answer the question. Even if you're still tweaking things today, what do you expect the useful lifetime of a batch of your enzymes to be, say, a year from now?
I mean, the judge is going to respond by sanctioning the attorney(s) for frivolous litigation. If your legal argument (for why the case shouldn't go to arbitration) has been rejected in court, initiating even one more case before the same court with the exact same argument could justifiably be considered a waste of the court's time. Initiate several of them and you're going to be fined; 10,000 and you're probably looking at things like contempt-of-court charges and disbarment. That's aside from the fee to initiate each case, as Chaebixi mentioned.

That said, if you're willing to risk all that to make a political statement - i.e. to pressure legislatures to change the law around arbitration - I can't rule out that it could be effective. But I suspect that other avenues for making a statement would be cheaper and more effective (and avoid the stigma of abusing the court system).

For example, how about just taking out TV ads? Find some maximally sympathetic victims of the arbitration system, and have them tell their stories. Less dramatic, but right now I think there isn't all that much public awareness of the issue - the New York Times' series notwithstanding. Arbitration is such a classic "big corp screwing over the little guy" story that I think a large number of even Republican-leaning voters would oppose it, especially the Trump camp (ew, but still), if they heard the full story. But most of them have probably never heard of it, or have only heard one-sided accounts that emphasize how class-action suits cost businesses and don't usually win plaintiffs all that much money. (Both of which are true, but ignore the fact that class actions are effective at holding defendants accountable for violating the law, and getting them to change their behavior - whereas a trickle of arbitration cases can just be dismissed as a cost of business.)
I often feel like there's a silent expectation that you should enjoy certain things if you're a good software developer. Here are some of these things that I definitely don't enjoy:

- Side projects

- Developer conferences

- Meetups

- Hackathons/hack-days

- Tech podcasts

- T-shirts/stickers for frameworks and technologies

I do enjoy software development though, and from what people tell me I'm pretty good at it, so I don't think it's necessary to enjoy these things to get a decent job. It does concern me when I feel like I'm the only one who didn't stay up late to watch the Google I/O streams live (I'm based in Australia)
$8M NSF Grant for Brain Computer Interfaces, Exclusive Interview with the Co-PI
In case it's unclear, I believe people are down-voting you because you speak as though everyone in the US is anti-Islam. The Trump government and their supporters may well be, but more broadly the anti-Islam sentiment is a fiction, especially among the intellectually curious and doing-our-best-to-be-welcoming HN audience. I know you probably meant well with your comment, it just feels bad because this is such a sore spot.
> "Software might mean the complete destruction of private property as a concept."

I can see an argument made for removal of the concept of intellectual property as something that's legally protected. It sounds like you're wanting to say something stronger. What's the step into the material world?
If cops are charging people that didn't even commit a crime then selective enforcement isn't really your biggest problem.
They also do payroll and other services which probably bring in a decent amount of money.
I also think it could be seen as realpolitik. I depends on how strongly you take "we create our own reality". Even Postmodernism has a kind of 'classical' version that emerges historically from Hegel, Kierkegaard, Marx and Nietzsche.

cf. https://plato.stanford.edu/entries/postmodernism/
The math on staying below 2°C of global warming looks increasingly brutal (2015)
Thanks for that link. I'm just starting to explore the biking roads around here and the history is interesting.
thanks, that definitely makes it easier to understand!
Since every government official or employee is a citizen too, there's less of a divide than you think, and that includes the cowardice. I agree there's cowardice here, but in this case the problem is cowardice of a few citizens who hold posts in the government, specifically the Dallas FBI, and even more specifically, dis fuckin guy Hopp. (Use your "Stevie Van Zandt as Silvio" face here.)

What kind of weak, fussy little scaredy-cat acts like that? Saying he doesn't have enough to do is being too nice about it. Judging from the facts of this story alone, he sounds like a vain petty bitch. Exactly the kind of person you don't want behind a badge, and a discredit to everybody else in law enforcement.
Dark matter may not have been detected yet, but we don't need to detect things directly to prove their existence. Sometimes, enough circumstantial evidence is sufficient.

For example, if you see a human-shaped shadow around the corner, you can safely assume that it's probably a human, even if you can't see them directly. It may of course turn out to be something else (maybe a scarecrow!) but that's okay.

Black holes are similar: we can't observe them directly but we can detect their gravitational effects, such as the way they bend light around them.
This is simple. It's Economics 101: Supply and Demand.

1. You work hard to improve yourself and gain more skills that people will want to hire you for.

2. More people will want to hire you

3. Demand goes up, while supply (yourself) is fixed.

4. Your price goes up.

On the other hand, if you care so much about your "life quality" and put absolutely 0 effort to improve yourself outside of work,

1. You don't have much to show other than what you did at current work

2. You are making yourself completely dependent on the company

3. When the company fires you, you have NOTHING to show to others. It's not like you can show people the code you wrote while you were at the previous company (the company owns the code and you're not supposed to share it outside publicly)

4. Since you have nothing to share, less people will get your value and less people will want to hire you

5. Demand goes down, supply fixed.

6. Your price goes down.

You can keep bitching about how the world is unfair and harsh and write some blog post that sounds almost like a beautiful piece of poetry, but that won't change anything, because that's how the world works.

It's not about companies "exploiting" employees by telling the m to work on something during the weekends. It's actually for yourself. If you don't believe that, that's fine, but you will stay a shitty developer and the law of supply and demand will kick in.
And this is why you should be very careful what you tweet. Once its out there it can never be deleted. Even with a fake name and handle. Your ip address, mac address, location, etc.
Mailchimp to set default to single opt-in
ok thanks that is way more informative of what they're trying to do. It's shotgunning, but with a relative blind eye to traditional personal network signifiers.
I have experience with PC engines boards in the past. They are good quality but the price is about 5 times what I am looking for, e.g. something about $20-30 to build a competitive network appliance with.
None of those points really apply though.

U.S. engineers generally get excellent healthcare coverage already.

As a non-French citizen the pension system is worthless to me.
That same pollution drifts over South Korea as well.
that is your opinion. why would i purposely misconstrue your comment?

i wish your answer now had been your original answer. i urge you not to assume malicious intent (that would be malicious) and consider that your original comment might have been saved from scrutiny given expansion.
When you connect with ftp or HTTP you get a top level directory or a home page. Same thing as looking through an open door.
Is it? Personal theory is consciousness scales, like we're more conscious than a bug, but a bug still definitely conscious.

Then like A.I. overlords / borg hive mind more conscious still.