skysight-inc/HackerNews huggingface dataset:
I agree with you, but I might suggest editing out the last sentence of your edit because that's like, rude.
I believe that's only true in flat or declining markets. Growth raises all boats, figuratively speaking.
The indictment doesn't say that Hutchins sold Kronos.

It claims that Hutchins was part of a conspiracy to sell Kronos, and that defendant [redacted] sold Kronos, but doesn't state that Hutchins advertised or sold Kronos.

The only solid claim against Hutchins is that he created Kronos, which doesn't stack up with his tweet asking for a sample of Kronos.

The following claim is that Hutchins and [redacted] updated Kronos.

It's not exactly a smoking gun.
Sounds like the standard playbook for startups. Oh you wanted a product, you should be happy with the mvp.
It wasn't always a $100,000 treatment. Shkreli made it a $100,000 treatment with the justification being that the poor could still obtain it for free. But then he puts a bunch of beauracratic roadblocks in the way and it's their fault they don't jump through his hoops? For a pill that costs $1 outside the US and which he made $750? Come on man.
Versus what? Relying on the goodwill of pharmaceutical companies? Seeing as this has been going on for a while but there haven't been lots of airtime about it until now, I'd say Martin's on the right path.
If your 32gb, 12 core server can't handle the 10 requests a second hacker news frontpage generates then you are doing something wrong. That being said, if you want to handle that by just spinning up more servers then that's a valid strategy - but you have to weigh up the costs.

You make a valid point about credits, but after one year you are hit with a huge bill. Hiding the costs of your infrastructure isn't always a good idea.

Why not buy 3 servers in different data centers for $120 a month. Is that enough redundancy for your infant startup? Why do you need to pay $100 month for a single 4gb, 4 core VPS from Amazon when you can get 38 cores, 120gb and 16tb disk dedicated servers for the same price?
*potentially.
The price increase for Retrophin from 12.50 to 750 was NOT for no apparent reason. The previous owners of the rights sold the rights cheaply because they were unable to make money selling Retrophin, and in fact had large losses for years, despite multiple large price hikes. Businesses that continually lose money shut down. Most of the costs are large fixed regulatory costs for each drug manufactured that a business owner cannot cut, so the only realistic alternative is to raise the price dramatically.

A USD 750 list price for a drug does NOT result in most people paying the list price. Most people get it via insurance, insurance companies pay a negotiated rate and you pay the copay (frequently higher than what the insurance company actually pays). Retrophin isn't a widely used drug so the effect on overall premiums was also tiny. His company literally offered the drug for free to anyone who for whom insurance didn't pay for it and who couldn't afford it. He also had a publicly stated business plan whereby he would use profits from Retrophin to invest in research into similar drugs which pharmaceutical companies have not been doing since Retrophin had been losing money.

Given the byzantine manner in which payments are actually made in the US, there simply isn't any other way to price an orphan drug, i.e. a drug that very few people actually need. The only way to make a business that produces life-and-death drugs needed by very few people sustainable is to price the drug very high due to very high fixed regulatory costs per drug manufactured. If you want to change this, it needs legislation and FDA reform. Demonizing businesses that raise prices to ensure they make a reasonable profit, will only result in drugs that are life-and-death for a small number of people either getting taken off the market or not coming to the market in the first place.

What's FAR more concerning is things like the recent increases in pricing for things like the Epi-Pen. Prices were raised 10x but also the expiration date on Epi-Pens is artificially short, so hospitals, schools etc are forced to throw away perfectly usable Epi-Pens for no good reason. Nobody talks about that because that price hike was by order of a senator's daughter. Shrekili just happens to be a bit of a PR nincompoop.

What we really need is a populace that thinks carefully and independently and a press that actually spends money on investigative reporting instead of relying on what politicians tell them to report, which helps their bottom line since it's much cheaper.
Have watched it. Worth waiting till it airs on Sunday. So far the best episode this season. #jamie v #danny v #dragon (hint should be enough for you to wait)
Yes, matt levine. Curious what his thoughts are on this case on Monday.
The Crown Victoria is quite pleasant to work on in general, although changing the rear spark plugs on my '86 was a huge pain--not as bad as a transverse V6, though!
I have a hard time psychopaths are quite as… blunt, frankly.

He pumps a lot of money into medicine research. He gave away drugs for free to people who couldn't afford it. Neither seem particularly likely for a psychopath, and even if they are, then it's a psychopath having a net positive impact.

He is, largely, just a regular but intelligent asshole. I'm getting kinda tired of seeing "charismatic, smart, has money" == "psychopath" lately.
Nowhere near enough space on Necker (my friend just went there) for a massive conference like this. Would be cool, though.
I often say rodent when I am trying to encourage my younger colleagues to use the command line.
> "Well this method of teaching is actually not as good as other methods. Would you do that?"

A university did a trial. Lecture with active learning vs traditional lecture and sections. Simultaneous versions of the same class; random assignment of students; pre-written exams. Inexperienced postdoc vs highly-respected well-rated experienced prof. Mid-term results came in. The comment was that if it had been a medical trail, they would have had to stop immediately, rather than finish the term. It would have been clearly unethical to continue to deny the control group the intervention.
But he wasn't arrested for any normal thing a security researcher would do - he's arrested for creating and selling malware... big difference.

The FBI could be wrong and that'd suck. I'm just assuming that the FBI and their resources have enough evidence to reasonably believe he's the creator.

And again, your last comment doesn't fit this article. They aren't overextending and arresting a security researcher (although he is one), they're arresting someone whom they believe is a malware creator and distributor.
Al Capone wouldn't have been prosecuted for tax evasion if he wasn't an infamous mobster.

This is how society's immune system functions.
> because a lot of legitimate security research when viewed through the myopic and cynical lens of a Federal Agent can be seen as illegal, this is an ongoing and ever present fear for people in the field.

While I tend to agree that this is possible, the parent's point was how unrelated this was to WC and to any research occurring in the field. It's strictly a case of "this guy wrote malware and sold it".

> you seem to believe fully this narrative of the FBI with no room for the FBI to view completely innocent actions as something else. No room for the FBI to be in error, no room for the FBI to be wrong.

I'm confused. The parent simply stated he was arrested for that. How does that translate into "Parent believes 100% what the FBI states with no room for the FBI to be wrong"?
Hetzner is my provider of choice. They are based in Germany (something I didn't consider when posting this), and their dedicated server costs are ridiculously cheap to the point of absurdity when compared to other providers.
I would imagine when he allegedly sold the malware it wasn't named "Kronos". He could have had no idea at the time that the specific campaign was his code, or perhaps had a suspicion and wanted to confirm it.
I think it's a cultural thing. There's something similar going on with Python and go.

Seems like a lot of people start with "getting types to go away makes a lot of powerful things easier". But eventually you a) get sick of typos causing runtime errors b) start to realise there are even more powerful things you can do with a non-broken type system.
I don't think it's rooting for a corporation, but a simple matter of ethics.
One thing to consider is: why is he the one who decides who can afford the drug or gets a free version? Seems horrible to me - we have laws to protect equal access to services like this (Medicare, Medicaid).

Another argument of his I found extremely disgusting is that he claims he's reinvesting profits from the price raise to further drug research. Ok, but again, we only have his word for that (and he's been convicted of fraud(!)). You can only claim you're smarter than the system and more responsible so much before people realize what's going on.
Merkle tree code that helps run Bitcoin was written by a grandpa aged person, cryptographic nonces were created by grandpas also and Satoshi and Hal Finney were of the grandpa group too. This generation can thank the last three generations no less, for the opportunity of cryptocurrency.
Did I say otherwise? Is there any doubt in your mind as to why they went after him though? How many other hedge fund managers do you know of that have ever seen the inside of a jail cell?
It was after the 3rd or 4th I realised that it wasn't written by Ludlum himself. GRRM might have planned for something similar.
Germany!
I like to use orm for simple projects. If there are some complicated queries or other heavy stuff I use views and stored procedures to make a suitable abstraction layer. Then I use the orm to access those views and stored procedure. Just to be clear, there is no business logic in those stored procedures.

Most orms generate awful sql queries, and then everybody wonder about bad performance (...and then they switch to nosql..because performance...).
Like every other language used for game development: you don't allocate objects in the render loop. All objects are re-used and go into pools. Malloc isn't free (heh): maintaining the free lists can kill FPS just as quickly as anything else.

As others have pointed out: the CLR has had a concurrent low-latency GC for a long time now and now that it's all open-source there is nothing preventing Unity from adopting it.
http://compleatlecturer.blogspot.co.uk/2017/06/the-compleat-...

Historically the original mode of lecturing was simply the transcription by the students of the manuscript the lecturer was reading.
Patient assistance programs are pretty common.

I'm on a $10k once every three months medication, and the drug company called to offer to pay any out-of-pocket costs up to $20k/year (deductible, copay, coinsurance etc.) I might have had, regardless of income.

The med probably costs them a couple hundred dollars in manufacturing, so they're happy to pay $20k/year to get $40k/year from my insurance.

(I turned them down - I have no deductible and a $15 copay, but plenty of others aren't in that situation.)
The main point of the article appears to be:

> You always have to design both “the product” your customers want and “the environment” in which your product will run in production. Thus any software product begins with two obvious categories of “work to be done.” People ignore this because it seems [counterintuitive.][going_there]
I mean, I see your point, but if that's what they have to do to stop fraud, and the fraud is something they really care about, then yeah, they should do that. Surely it's no great tragedy that stores have cash registers and bill checkers.
Right. But thing is, they are not actually equal on specialised matters? I understand that it works when you're dealing with things like murder. That can be relatively clear.

But how about hacking? Securities fraud? Money laundering? Tax fraud? These are all highly specialised issues that the average person knows nothing about. No average person, unless they have an interest in it, will be able to make a good call on such a case.
Not trying to play contrarian here, but are there any reported cases of people who've actually died for lack of Daraprim?

> Find one person who got it for free

This guy got it free, for life.
http://www.news.com.au/lifestyle/health/health-problems/this...
Given that they control the hardware and software, I believe they know full well what they're doing when they put out a new update to devices that cannot handle it. They could provide a warning "During testing, your device may not run at full speed, due to age of hardware and new features added." and offer to install.

With Microsoft, I give them a bye primarily because aside their Surface line, they don't control every possible configuration, and have to deal with a wide ecosystem of hardware.
You think the FBI is going to interdict a computer criminal before they spend a week in Las Vegas associating with computer security professionals, any of whom could be criminal co-conspirators?†

That would be exceptionally nice of them, but also extremely poor investigative practice.

I will say, though, as one of the many people in my field that is bone-tired of schlepping out to the worst place in the United States every damn year for these events, any other location in the world would be fine for me, and I endorse the actual suggestion you're making.

† (Yes, obviously, I know virtually nobody who attends Defcon is a criminal).
I'm just pointing out that disruptions are nothing unexpected if you travel often - you can't really expect extraordinary treatment. (Sure, in the EU at least you get food and lodging by law - but lounge access is a completely different beast.)

After all do you expect to be put in first class just because a weather or security issue caused your flight to be cancelled? You aren't the only person affected, airlines can't handle everyone like a snowflake.
Yeah, agreed. The one other issue, though, is that I think it's wrong to evaluate the quality of each device in isolation. From Apple's viewpoint HomeKit will be a success iff there are a wide range of quality products for it. They're trying to sit at the center of an ecosystem, and that means not just offering quality but hitting critical mass.
All your house are belong to us. - Apple.

Being tied to a cloud service is unacceptable. Cloud services only have lives of a few years before they disappear or change incompatibly. Houses need 20 to 50 years of support.
The books were junk, honestly. They were the same kind of doorstop novels as Wizard's Last Rule and the Wheel of Time, just with more nastiness, and they are showing the same flaws as those books. Do a standard epic fantasy, bloat it into at least seven novels, and add some transgressiveness to make it spicier.

I think the SF/f genre has really struggled lately...stuff like Brandon Sanderson writes feels so lightweight compared to even the second tier authors of the past, and there's very little flavor in books now; it's formulaic and narrowed to such a tight audience.
There is already a similar huge convention held annually in Germany, the Chaos Communication Congress. It's quite well attended.
Here's Miguel's blog post from a couple years ago (before the Microsoft acquisition) when their cooperative mode GC first landed:

http://tirania.org/blog/archive/2015/Dec-22.html
Thank you for this. I have been using VS 2017 primarily for last 6 months as I enter the .net world and thought many of these complaints were me / my substandard machine.
I dont' see why crypto going mainstream is a reason to get out. Look at what happened to facebook. Everyone's mom, grandpa and, great grandma is on it and it's still growing.
Got a source for the "suffering"?

also, iirc the patients that need that drug are literally low triple digits if not lower. making sure they all get it one way or another is not exactly a challenging logistics problem. imo it's more of a marvel that something so niche is available at all.
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By what factor does using GraphQL accelerate development time?
For the record, cemu is closed source.
That interview changed my point of view as well. It does indeed seem like hypocrisy, and like the competing and stronger drug companies set up this publication lynch. I can't believe that out of all the strong drug companies, the first time a drug was increased in price is this poor 2015 founded company. Why is it, that the first time we hear about this common practice in drug industry it's within this relatively new company?
Unbeatable Squirrel Girl by Ryan North (Dinosaur Comics) has a few panels about this recently:

https://twitter.com/thesizeoffun/status/893479366235230208
The menu bar, or rather UI problem is really annoying and in fact is cross platform.

I reported it [0] for Windows few months ago, and not a reply :(

[0] https://github.com/keybase/client/issues/6541
Well he committed fraud but people did not lose money. So yes to question 2 and no to question 1.
The Problem with Meal Kits
Although, interestingly, he didn't steal their money, he lost it in a bad trade, which is probably (maybe?) covered under the risks associated with the fund's operation. The deception was not telling people their money was gone (and also lying somewhat about details of the fund initially). Given that the loss was an accident that he didn't profit from, and that he worked to repay the money, there's a critical difference between your example and what's reportedly happened here, which is intent.

It's more similar to you managing a property for someone, and telling them you got fire insurance when you haven't yet, and then when the house burns down accidentally you work to make the money to cover what the insurance would have covered. You did commit fraud by not getting the insurance when you said you would, but you also covered the costs in the end.
Interesting tidbit about the meta here:

------

> > One thing has definitely changed: the last time LWN wrote a critical piece about the project, we had some AOOers drop by to repeatedly complain about what a bunch of meanies we all were for criticizing them instead of volunteering to help them out. This time? Crickets...

> ...or they are not LWN subscribers, and nobody posted a SubscriberLink somewhere they could find yet.

> Last year I had posted a SubscriberLink to a LWN article about AOO to HN; I'm doing it again right now, so if they read HN and my post reaches the front page there, we might be able to see them here again.

-------

I'm not sure if HN is really supposed to be used like that..
Location: Poland

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Résumé/CV: https://view.attach.io/SkfIhyOix

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Except that adapter has a max voltage of 0.5v IIRC, which significantly reduces the quality of any high impedance headphones.
The Register posted about this mystery 4.1.4 security fix mentioned in the board minutes back in April. After the article was published, the meeting record appeared to have been edited and any mention of security fixes removed (with time stamps in the apache directory list revealing as much) - https://www.theregister.co.uk/2017/04/28/apache_openoffice_n...

It was also quite telling that when a security vulnerability in 4.1.1 was discovered, at least when checking the wayback machine the earliest security announcement was posted at April 29th 2015 ( http://web.archive.org/web/20150429084734/https://www.openof... ) and while multiple snapshots have been captured since ( http://web.archive.org/web/20150501000000*/https://www.openo... ) it took until November 1st 2015 for the recommendation to change from "delete the .dll" to "upgrade to 4.1.2" ( http://web.archive.org/web/20151101015732/https://www.openof... ). At least until September 24th 2015, version 4.1.1 was still the latest version and the recommendation to delete the .dll was still present ( http://web.archive.org/web/20150924061922/https://www.openof... )
When I first saw the "This is Unix ... I know this" scene in Jurassic Park, I had to restrain myself from leaping up in the theater shouting "YES!!"

All those lost hours typing at a green-screen terminal qualify me to be the hero in a Hollywood movie too!
I'd imagine the roadblocks are there to prevent people abusing the system. And the rest of the roadblocks are by the FDA and perhaps CBP, right? Otherwise people could just import the $1 pills and be fine.

If it turns out Turing was acting malicious and intentionally tried to block people from getting the medication despite knowing they were eligible, that's a different story. But I'm hardly going to take the word of biased medical professionals on it.

Martin put a face to all this, pointed out a huge flaw in this system and made money doing it. Then to top it off, he dares to laugh at everyone in the system about it (like in [1]).

If Martin had just hid behind normal pharma PR, few people would be outraged, it'd just be general grousing with little airtime.

1: https://www.youtube.com/watch?v=2EXsVfiFbp8
We don't know whether he did or not. But if they have evidence to support arresting him,
the US has an extradition treaty with Britain; they should have shared it and asked British authorities to make the arrest. And there very well may be evidence, especially if the timing is related to something new obtained from the Alpha Bay takedown and it happening when he happened to visit the US for DEFCON was a coincidence.

But running a snatch and grab at a security research conference looks really bad, and is bound to have a much wider chilling effect on people's willingness to attend US conferences.
It is a file manager though.
Unfortunately Martin was made a scapegoat and they made an example out of him because of his arrogance and vocal personality. How did the executives that caused the financial crisis of 2008 get off completely free but a relatively tiny hedge fund manager get the book thrown at him? This was a witch hunt, no doubt about it.
The judge/jury distinction is basically orthogonal. Judges who hear a case are not necessarily experts. And by the same token, one could easily imagine a system where a jury had to be composed of experts in the field. I'm not convinced that would be a good thing to do, though.