skysight-inc/HackerNews huggingface dataset:
"... While most people troll this scene for its usage of 3D graphics on screen, she’s actually using a real 3D filesystem called FSN."

That's not a filesystem.
http://jesuschristsiliconvalley-blog.tumblr.com/post/4653927...
There seems to be a misconception regarding what Shkreli was found guilty of. The legal case here has very little to do with the pharmaceutical pricing controversy - it is a separate case based on a separate hedge fund that he managed. The gist of it is that he took people's money to start a hedge fund, lied to investors that the fund was doing fine when the hedge fund went belly up, but ended up returning everyone's money plus a sizable return when his separate pharmaceutical venture went well.

When fraud happens those affected don't usually get their money back much less a return on that money. However, it's pretty clear what he did is also fraud (false documents, not returning people's money when they asked for it) even if the fact that investors came out better makes the plaintiffs less sympathetic.
>The side effect of the price hike was the insurance companies has to pay more, not individuals.

I keep seeing this, don't you realize that those increased insurance costs are passed on to the people paying for insurance?

>He raised the price of Daraprim in order to fund R&D to find alternative treatments as Daraprim caused some nasty side effects.

You shouldn't buy into his PR efforts, take a look at this:

Shkreli admitted his company sold the same form of pyrimethamine, or Daraprim, that had been on the market for 70 years — although he expressed hope that his company could develop a more potent form of the drug that did not hinder the body’s production of folic acid.

“The mechanism of the drug is folate inhibition,” Anandya reminded the CEO, adding that what Shkreli had proposed might not even be scientifically possible.

“The entire mechanism of the drug is to stop the production of folic acid in the first place and the bulk of its side effects are tied up with that,” Anandya said. “It’s kind of counter-intuitive to say that you are going to solve this problem when it’s not a problem as much as the whole raison d’etre of the drug. This I find is the main problem with your plan. That the solution is not worth $749.”

“One cannot suggest such a (monstrous) increase in the price of a drug which by your own admission does nothing better while telling me your plan is to (because this is the only way it would work) create an entirely new drug not related to pyrimethamine at all because it would require a new structure,” the physician continued. “Which in turn would give you a big hassle since you would require testing and FDA approval from scratch anyway. I think your plan is flawed.”

from: http://www.alternet.org/economy/pharma-bro-martin-shkreli-ge...
1. There is no evidence of any R&D efforts. He did "market research", i.e. finding new drugs to acquire and hike the price on.

2. It was absolutely 100% not free to any individual who wished to obtain it. If you had no insurance you might (or might not) get it for free, but if you had lousy insurance you could get stuck with a 20% copay, which means you have to pay $18,000 out of pocket -per month-. Also, hospitals stopped having Daraprim in stock because of the price hike which means people with acute cases are no longer able to start treatment immediately.

3. If you can't argue he hurt a lot of sick people, why are doctors and other healthcare professionals arguing exactly that?

I think you've been drinking the Shkreli cool-aid.
I believe he corrected the price of a drug. & no one went without. Those unable to pay for insurance got the drug for free.

Also, I said two major flaws. Obviously, ppl have many flaws.

Edit: It's economic illiteracy if you don't understand that. If you have evidence which says otherwise(?), I'm happy to look at it.
Can you elaborate? Have you been creating malware (banking trojans) and selling it online?
It is obvious from epistasis' comment that (s)he is fully aware of the difference between power and energy, and also that both are relevant properties to consider when designing an energy storage system.
I wouldn't say it's a dead project. The stable release is doing fine - we just incorporated it into a new project recently.

Facebook's teams have a lot of projects going on I wouldn't be surprised if they're focusing on something else.
What makes you think TV accurately portrays anyone?
I would go one step further and claim that SQL-databases are overkill for most purposes. Relational logic is very useful, as is transacted storage and indexing; but the SQL-standard is clearly overkill in many cases.

An ORM is a simplification; it offers a single, convenient, but ultimately limiting perspective with most complexity swept under the rug. Anyone who's actually tried migrating between different databases or spent a week or so chasing down nasty coherency/performance-problems in their chosen framework knows what I'm talking about.

A more constructive approach that's rarely taken is providing storage/indexing as first class abstractions within the language to build your storage logic on top of.

Embedding raw SQL in a piece of software makes it much harder to reason about and maintain. Since storage/indexing are often fundamental, they deserve a more sophisticated interface than simply passing written notes back and forth on cocktail napkins.

Lately, I've been implementing my own, special purpose storage/indexing (https://github.com/andreas-gone-wild/snackis/tree/master/src...) to cut down on the complexity and get a tighter fit with the application.
That doesn't make my previous statement any less true.

Also, I'd suggest focusing on the wider picture. Price gouging on a single drug may have a minimal impact, but there have been numerous cases of drug companies artificially hiking prices of their products, which does make a substantial difference. There are numerous studies into this if you're interested.
That is purpose to your life though.

I spend most of my time watching TV and playing games. That's a lack of purpose.
Why can't films and TV accurately portray doctors? Or any other profession ...
It exposes it. Not quite as monumental, but a Snowden moment. Remember, congress did squat about the price gouging, because that's what they get paid to do.
Nice throwaway, pal.
It is possible to be upset with both the system and the people using it.
The contrast here is great.

Finding the problem and creating a solution along with focusing on the process of creating that solution in order to reduce risk of building the wrong solution. Contrasted to building a solution along with a sane dev and production environment for that solution to fit in, to increase possible iteration velocity by reducing deployment inertia.
Actually, it's more complicated than that. It's not entirely Oracle's fault - Sun made third party developers' lives very painful and wouldn't accept patches without an enormous amount of red tape. They essentially caused the split when Michael Meeks was forced to create the Go-OO fork where he produced a build that merged in a huge number of patches that were backlogged from the main tree.

When OpenOffice pushed back (and after they completely shafted Kohei's effort in contributing a solver for Calc) they in essence told the wider development community that their contributions weren't welcome and forced the creation of The Document Foundation to govern the development of LibreOffice. The TDF then worked out how to be welcoming, lowered barriers to entry for new contributors massively, put in infrastructure like gerrit and opengrok, majorly simplified the build process and generally showed a lot of love to their developers. At this point it was game over for Apache OpenOffice, and now everyone contributes their code to LibreOffice. Which is an utter no-brainer really - why send your code to a bunch of people who arrogantly think your efforts are by default crap as you have no experience with the codebase?
>I find him pretty charming and unbelievably intelligent.

Isn't that part of why people claim he is a psychopath? Smart, lack of empathy, easily gains people's trust, and charm all bang on for traits for psychopathy.
[0] "... it says that the drug is available for free to people with deep financial need. But Dr. Aberg has watched her patients have to "jump through the hoops" to get it. Patients have to prove both financial need and health status, something that's difficult to focus on when their lives are in danger. In June, one of her patients gave up on the process. The patient switched therapies, only to suffer a negative side effect."

[0] http://money.cnn.com/2016/08/25/news/economy/daraprim-aids-d...
We dont know what was actually sold, or what was paid for, or who paid for it.

Of course the government in a government indictment will states "he sold malware" but the government is known to lie, exaggerate, and use terms incorrectly or out of context when talking about technology.

Taking the indictment at face value is IMO extremely naive
> ... Also, please stop pretending your best guess is some sort of calculus over complex corporate politics...

I think you should try to be more civil on HN. You can't just bash someone because of their guess.

> The converse of this that is equally true: Just because you don't feel capable of doing it doesn't mean I should not.

I don't want to get into some argument with someone who feels he is the only guy capable of achieving a failure.
See reply from Sharlin below:

> It's just poor writing. Either you paraphrase what people are saying, or you cite someone specific.
This is absolutely not true. You're speaking out of your ass here. 0 people died. If they couldn't afford it HE GAVE IT TO THEM FREE.
I find it hard to believe that he got a fair trial this time around. He was already tried and found guilty in a trial by media a few years back. This investigation & prosecution are a direct result of his legal actions that didn't play well politically. BOTH presidential candidates condemned him. To me it's sad. The sacrificial lambing of Shkreli instead of lawmakers addressing the underlying problem of costly pharma is probably the most Venezuela thing I've ever seen happen in the US. They made the system, he's just trying to prosper ffs.
I think the biggest plus for using an ORM is increased security over rolling your own interactions with the database.

Plus the time savings/overall security using a framework that is typically tied to the ORM.

So I would recommend using a framework and ORM.

If you're just getting started and are working on a web app for your own use I would recommend building at least one from scratch. Rolling your own Auth, etc. Once you do that you'll understand more of what appears as 'magic' in a framework like Rails/Laravel.
> still appears to be an infinite supply of new reasons how things go wrong

Very true, but then there's divorce, that perennial cause of problems.
I like that you asked this question and I'll probably refresh this page a few times to read the responses.

I use an ORM called odb by CodeSynthesis. It is one of my favorite ORMs and an extremely high quality product. This ORM has saved me in more ways than one, but the biggest benefit is exactly what you've described.

I can't speak to other ORMs, but odb has such a nice system that it makes C++ development involving databases tolerable. Prior to this, managing queries, transactions, and keeping on top of problems related to interactive with specific databases was a real nuisance. There are enough quirks and differences between databases that I feel like it's too easy to understate what a pain the differences between variants of SQL can actually become in a large project.
It doesn't inspire confidence that they questioned Shkreli, who was a relatively small player in the medical space, while a senator's daughter was in the middle of one of the most egregious price gouging schemes in recent memory. They even wrote legislation to make it mandatory to carry their product in schools and public buildings.

The Shkreli inquiry reeked of hypocrisy and grandstanding. Those congressmen knew perfectly well what was going on, and many of them receive contributions from companies involved in it.
Electronic filing systems, and freely searchable dockets/filings have been available by various clerk of courts for sometime.

Some of these clerk of courts also include public record searches, which I have used for deeds and other publicly recorded documents. Other record offices can be separate offices from the clerk of courts.

Unfortunately, clerk of court systems (online or off) are neither universal, integrated or interoperable. And though you might think SCOTUS would take the opportunity as you say, they are about the slowest moving and beholden to tradition of all the courts (as evidenced by them developing this late in the game or still not allowing video of hearings).
So, it is okay to lie to investors, as long as you eventually pull a success off? And you make those investors you were lying to money by committing fraud on the investors in your new company (Retrophin), so they make money, but not as much they would have if you weren't secretly taking profits to pay off the investors you previously defrauded?
I'm willing to bet that Mono GC has improved a lot, but I don't think that Unity frequently updates the runtime. It's kind of painful, from what I've been told.
> It was free to any individual who wished to obtain it, with Martin footing the bill.

[0] "... it says that the drug is available for free to people with deep financial need. But Dr. Aberg has watched her patients have to "jump through the hoops" to get it. Patients have to prove both financial need and health status, something that's difficult to focus on when their lives are in danger. In June, one of her patients gave up on the process. The patient switched therapies, only to suffer a negative side effect."

[0] http://money.cnn.com/2016/08/25/news/economy/daraprim-aids-d...
I don't know enough about cybercurrency ICO's to say if this analysis is correct. But if it is, it's puzzling, since Juan Benet really doesn't seem to have started Protocol Labs for the money. Maybe he really thinks that they could put $700 million to good use.
If you make money on a trade, someone else is losing money. That's nothing new.

Where he went wrong is going into the healthcare space with that attitude. Shkreli thought that he didn't care about the bad PR it would bring him, but the microscope on him ended up uncovering illegal behavior.
You might find FedEx's origin story interesting.

> “I asked Fred where the funds had come from, and he responded, ‘The meeting with the General Dynamics board was a bust and I knew we needed money for Monday, so I took a plane to Las Vegas and won $27,000.’ I said, ‘You mean you took our last $5,000— how could you do that?’ He shrugged his shoulders and said, ‘What difference does it make? Without the funds for the fuel companies, we couldn’t have flown anyway.’ Fred’s luck held again. It was not much, but it came at a critical time and kept us in business for another week.” [0]

[0]: http://www.huffingtonpost.com/2012/10/15/fred-smith-blackjac...
Was it the nazis or soviets (or both) who made effectively everyone criminal so that they could then persecute them at will?
Edit: Whoops, different person. See bottom.

> Nowhere was I (or you) saying anything about this case.

Your specific words in your original response were "He's human garbage, let him rot." That response was to me saying I think the details of the case lead me to believe that I think he should a light sentence.

You very specifically noted through that euphemism that you think he shouldn't get a light sentence in this case because he's human garbage.

Edit: Sorry. That was someone else. I was specifically asking in context, but that wasn't you originally. Mea Culpa. Leaving it here with this note so people that saw it previously can see me retraction.
TOD upgrades don't get lounge access since domestic F doesn't get lounge access.
Your characterization of startup cloud costs is laughably outdated. With credits for startups and the ability to go serverless, I've known startups that didn't pay a dime for hosting their entire first year despite reaching the threshold of hundreds of customers and over $1m ARR. One of my friends actually started doing some ML stuff on AWS because he wanted to use his remaining credits before they expired and his production and staging workloads weren't going to get him there.

I'd say it makes no sense to buy your 32gb, 16-core single point of fail, waste $40/mo and half a day setting it up and then have to keep it running yourself when you can easily spin up an API in API Gateway/Lambda that dumps data into dynamo/simpledb and front it with a static site in S3. That setup scales well enough to be mentioned on HN without getting hugged to death and is kept running by someone else. And if it is, literally, free for the first year, how is that not a no brainer?
Of course we care. People are criticizing the pharma industry's practices and calling for change all the time. Shkreli is a particularly obnoxious symptom, but he's not the disease.
> * What is Blue Apron's reason for the job cuts?

Companies sometimes increase headcount before a fundraising event to create a signal that growth is occurring, or to maximize one area of visible growth as much as possible. This headcount is not always needed after the raise.

> * Was this going to happen anyway or was there increased pressure from the IPO?

After funding the company can focus on essential expenditures and focus its growth and revenue targets on what matters most to investors. It's a good thing for shareholders to cut costs, since headcount can always be increased again when necessary.
Indeed, this is the Gell-Mann Amnesia effect:

"Media carries with it a credibility that is totally undeserved. You have all experienced this, in what I call the Murray Gell-Mann Amnesia effect. (I call it by this name because I once discussed it with Murray Gell-Mann, and by dropping a famous name I imply greater importance to myself, and to the effect, than it would otherwise have.)

Briefly stated, the Gell-Mann Amnesia effect works as follows. You open the newspaper to an article on some subject you know well. In Murray’s case, physics. In mine, show business. You read the article and see the journalist has absolutely no understanding of either the facts or the issues. Often, the article is so wrong it actually presents the story backward-reversing cause and effect. I call these the “wet streets cause rain” stories. Paper’s full of them.

In any case, you read with exasperation or amusement the multiple errors in a story-and then turn the page to national or international affairs, and read with renewed interest as if the rest of the newspaper was somehow more accurate about far-off Palestine than it was about the story you just read. You turn the page, and forget what you know.

That is the Gell-Mann Amnesia effect. I’d point out it does not operate in other arenas of life. In ordinary life, if somebody consistently exaggerates or lies to you, you soon discount everything they say. In court, there is the legal doctrine of falsus in uno, falsus in omnibus, which means untruthful in one part, untruthful in all.

But when it comes to the media, we believe against evidence that it is probably worth our time to read other parts of the paper. When, in fact, it almost certainly isn’t. The only possible explanation for our behavior is amnesia."
I got Vicodin and prescription Ibuprofen after oral surgery. I preferred the Ibuprofen because it felt more effective for keeping the pain away, and the Vicodin made me intensely sleepy. So... I never experienced anything that would make me want to keep taking it. I kind of avoided it because I didn't want to be sleeping all day.
Can we please have a conversation on the abuse of Federal plea bargains and insanely high sentencing guidelines? Thousands of Americans every year plead guilty in federal court to crimes they did not commit because they face insanely high prison terms if convicted. Often Federal sentences are several times longer than ones in state courts for the exact same crimes.
Yeah, I think he's better at excel than I've ever been at anything. Jesus.
Sure, but the solution is not to wish that people like Shkreli don't raise prices on their drugs. Instead, we need to reform the US healthcare system to stop problems like this.

Many drugs of similar kind, as Shkreli would point out, have a similar price. The difference is that those drugs are owned by faceless pharmaceutical companies with PR teams. Shkreli was an obnoxious person who was doing an obnoxious thing and as a result the government swatted him with some unrelated charges (Incidentally, I thought his defense of "I didn't commit fraud, because all investors made money" was a pretty good defense).
If our justice system behaves dishonorably, then the world's information security industry should certainly abandon the U.S. We can have our solo conferences, but we can't ask foreigners to risk incarceration for our convenience.

The Bahamas might also be a reasonable choice, as they only declared independence from Britain in 1973.
Honestly, I would be thrilled to triple my money in 18 months. Using the gambling analogy is disingenuous though.
What if he lied to you, but then went out and through a combination of talent, hard work, and luck somehow made the money to make you whole and then some?
Fusion, of course. It actually is right around the corner now, this time.
The timing does not shock me, it is most likely they flipped someone when they took down Alpha Bay which was recently
Shouldn't this stop being an issue under Microsoft's patronage? .NET definitely doesn't have a stop-the-world garbage collector and this should trickle to Mono, if it hasn't already.
Let's just put it this way: as far as Hollywood is concerned computer systems are the new quicksand, and hackers are the rope that's needed to get out of it.
What is a "scripting" language? At this point JavaScript has effectively become a general purpose language. And one that usually gets transpiled and then minified for production anyways. Plus, since WASM is essentially for providing libraries to JS code, is there really much of a difference to either the developer or the end user between including a JS library via npm and a WASM library?
> Even John Maynard Keynes, the father of modern economics, attributed our irrational choices to “animal spirits.”

Yeah, there's an equivocation in this reference. The "animal" in "animal spirits" doesn't refer to non-human lifeforms, rather it means "of or relating to a soul". The expression itself is an obsolete medical term which designated what people from late antiquity to the modern period thought was the cause of bodily movement.

By the early 20th century, it had become a somewhat quaint and tongue-in-cheek expression. To say that someone was "full of animal spirits" was to say that a person was lively, restless, or something like that.

There's without doubt a conflict between rationality and irrationality in Keynes' usage of it. But that conflict isn't alluded to through a reference to "animals", in the contemporary sense.

https://en.wikipedia.org/wiki/Animal_spirits_(Keynes)

https://neurophilosophy.wordpress.com/2006/11/16/exorcising-...
He started his career as a short seller that defrauded banks: https://en.wikipedia.org/wiki/Martin_Shkreli#MSMB_Capital_Ma...
No I haven't created or sold malware.

But i have this; A middle-eastern last name, I use Tor, I use Linux, and I use Telegram, I am active in the field of IT and especially enjoy IT security.

I know that I can be held indefinitely if I visit the USA. In the USA you're guilty until proven innocent, unlike the rest of the western world. Simply going to the USA is more risk than it is for practically every other country. Well, for me, and a lot of people like me.

That's what my comment was about.

EDIT: How is it relevant to the article? Well, he is an IT security specialist who wanted to visit DEFCON. Yes, I understand what he did was wrong, it was his own risk.