skysight-inc/HackerNews huggingface dataset:
here's a TODO list i made for possibly interesting genome editing targets: http://diyhpl.us/wiki/genetic-modifications/

Many of these have low demonstrated correlation or significance so don't just blindly load everything on that document into your at-home CRISPR kit http://www.the-odin.com/gene-engineering-kits/ but it should be a good starting point for thinking about what can be modified, improved, disimproved, etc.
If you see children as a "serious competitive disadvantage", you've answered your own question...at least for now, you may change your mind later.

Being a parent is the single most challenging and rewarding thing I've ever done. Nothing else comes close. If you're asking a ton of questions, you're not ready.
C doesn't have "memory" in the standard. They're pointers into a contiguous object, but anything before a[-1] or after a[sizeof(a)-1] is undefined aka it actually doesn't exist.
and they put a note in the manual that says "if you drive over 70mph on a hot day it will definitely explode so don't do that"

so if you buy that car and you do that, it's your fault regardless of how poor the car design is
What if you are coding a 3D demoscene program for your thesis, because it illustrates a beautiful mathematical proof?
The version I got, in a tech company interview, was how much longer would you need to make the rope to allow a cat to go under it. They were basically just look for 2 x Pi x Cat in this case.
Four optical illusions that reveal the hidden workings of your brain
Chance is not 'mere'. Whatever you think high complexity is, is just as well a low complexity to a different perspective. We are only slightly more remarkable than dirt, and over 4.5 billion years of chemical history, I don't see what you're basing your objection on.
Track record for 134 science/tech predictions
yes I'm aware that parsing a letter as an an integer is undefined behavior, it's in the manual
I have an anecdote about a religious college that bans alcohol, and students would get drunk outside and drive back drunk, so there's a lingering question about whether the policy saves more lives in sum.

I don't see the same complexities or side effects with banning video games, TV, or even weed.
Why exceptionalism is dangerous for startups
• All my friends are already there (and many of them are thousands of miles away from me) so it’s a convenient way to stay in touch or just get a passive awareness of what they’re up to. Other services don’t fill that same niche for me.

• It’s an easy way to organise events and participate in small online social groups for common interests or memes or whatever. (It’s a partial replacement for forums and newsletters.)

• My newsfeed is now mainly stuff that’s interesting & relevant to me—hell, even the ads sometimes—because I’m proactive about unfollowing people who post stuff I don’t care about, hiding uninteresting content, and reporting spam.

• Even though I was an active user before, I worked there, and after having met many of the the people running the show, I generally trust that they’re technically competent and care about making something useful & good for people.
I don't see how talking of a late stage of capitalism presumes a known end state. It only requires the assumption that 1) capitalism is not going to be around forever, and 2) we're closer to the point where it's going to be replaced by something else, than we are to the point where it replaced the socioeconomic system that preceded it. You don't have to believe that the following system is necessarily socialism or communism, nor do you have to believe that it's going to be the last such transition.
There are obviously exceptions - the last bit of the article kind of explained that.

>But what the Maastricht study can do is provides highly credible evidence that marijuana legalization will lead to decreased academic success — perhaps particularly so for struggling students

Basically good students will continue to.be good, but the bad students will suffer.
American Runners Have Never Been Slower
never said C was a great language, merely indicated that it's important to distinguish between a mistake made by a programmer and a failure of the language

pretty sure trusting user provided data without validation is the programmers fault regardless of language
Isn't it more than just aggressivity? Isn't even the normal attraction and pursuit of attractive females now more or less negated/disincentivized or worse?
It's not that far away. You just need a clear day and get a little up above

https://www.google.com/search?q=fuji+from+tokyo&source=lnms&...

Los Angeles also as mountains, they aren't nearly as far but they are also usually blocked by haze and other obstacles. But on a clear day...

https://www.google.com/search?q=los+angeles+mountains&source...
the parents analogy is quite bad since C doesn't shoot you in the foot unless you pull the trigger

closer to a gun without a safety, which plenty of manufacturers sell
>Ultimately we are in dire need of regulation of these substances, especially where there is food contact.

We don't need regulation. We need consumer education (and in this gov funded programs can help) and entrepreneurship to provide the market with what it demands.
You are forgetting that Zerodha needs you have a demat account and then you pay for it. Because you can't do MF with Zerodha w/o a demat account (can do so with many other brokers).

Also, for this monthly charge Zerodha doesn't provide any analytics or advisory while many other direct fund providers, at a similar monthly cost, do (and couple of them won't even ask you to have a demat a/c and pay for it).
If Sega suddenly open-sourced the Genesis hardware, all it would do is make the emulators better. It wouldn't make people start writing new Genesis games, or whatever it is you're worried about happening here. Whatever negatives there are to Flash, they would not be affected in any way by the player becoming open sourced.
>It’s a myth that doctors even take this oath.

Not really:

"In a 2000 survey of US medical schools, all of the then extant medical schools administered some type of profession oath. Among schools of modern medicine, sixty-two of 122 used the Hippocratic Oath, or a modified version of it."
Not only those chemicals but https://en.wikipedia.org/wiki/Xenoestrogen and endocrine disruptors generally.

Palm Oil and Triclosan are everywhere.
QNial7 Array Language Announcement
Q'Nial, the language interpreter developed at Queen's University for the Nested Interactive Array Language, Nial is now available in a revised version that supports both 32-bit and 64-bit architectures. The open source code can be used to build versions for both Unix and Windows operating system.

Nial is a very high level, general purpose, language based on a formal model of Array theory, developed by Michael Jenkins and Trenchard More, that influenced the development of APL2. Q'Nial is a C based interpreter with efficient, tuned, implementations of basic array operations.

As such it supports computations of large data sets that can be numeric or symbolic data. The programming style is highly functional but can be used in an interactive way to experiment on data and build functions incrementally. It combines concepts from APL, Lisp and functional programming and supports Algol-like control structures.

The implementation is competitive with other array languages such as J and APL as well as other interpreted languages with array libraries (Python/Numpy, Lua/Torch).

Nial has been used for rapid prototyping in areas as diverse as insurance underwriting, question/answering systems, composing music in a specific style, and a variety of artificial intelligence applications.

The repository is located at:

http://www.github.com/danlm/QNial7

This repository includes binaries for OSX, Linux, Windows, and Raspbian that can be downloaded and used directly.

Coordinator:
Daniel Martin

Contributors:
Mike Jenkins
John Gibbons
Stu Smith
I just had a baby boy two months ago, I also work and go to school at the same time. My wife is staying home to raise him but she is quite content.

Having a kid forces you to think about what you're leaving behind on the planet. The realization that there's a little one who is going to look up to you for every little thing makes you really question and think about your own point of view, your own ways of doing things.

I felt like I became a leader when I had my son. It changes you in a way that nothing else quite can. It opens your heart. Check out The beginning of life on netflix. It's quite an eye opening piece.

I would almost posit that if you are going to be successful, then you can certainly be successful regardless of having a kid or not.

I also don't think any material success is quite so valuable as the experience of having a child. I know millionaires that decided to never have kids, and I wouldn't say they regret it, because that may be harsh, but they certainly would reconsider their choices.

I think world view defines a lot of it as well. I subscribe to my own esoteric beliefs. I believe in karma. There is an intangible joy, happiness, and luck that kids bring. They've certainly blessed my life. :)
I am not sure but maybe the people who later might help this company or required for its success - future VCs, top talents they would want to hire, press coverage and all - might be influenced by the YC tag and it might work for Piggy in this way. And the YC networking as they say.
For anyone actually interested in learning how hard southern Wisconsin has worked to get manufacturing back after the GM plant closure, I recommend Janesville: an American Story. Suffice to say that many, many people both R and D want these jobs in Paul Ryan's district and willingness to offer incentives is fully bipartisan. https://www.amazon.com/Janesville-American-Story-Amy-Goldste...
This is not data, but in my peer group there is a strong connection between those who dropped out and those who had self control issues with any of those.
I quit smoking weed years ago when I noticed when I was reading that I had forgotten the meaning of some words that I once knew. Smoking is great until it makes you stupid.
I finally registered an account just to show how much I appreciated the double entendre!
What happened when the students lost access to Adderall?
Especially in America
Another good one is Mt. Diablo to Mt. Lassen, which is around 180 miles. That's the longest one I have seen in California. Tom Stienstra claimed it's 180 miles, which is a long way. [1] Other sources claim somewhat shorter distances.

[1] http://www.sfgate.com/outdoors/article/Clear-viewing-from-Mo...

(Oops somebody already pointed it out!)
When Terminal.app itself is in Secure Entry mode, you can still paste, so I don't think your hypothesis is right :/
How to Rip DVD for iPod with DVDFab DVD Ripper
It's a study. It should be released regardless of agendas or politics or if it didn't agree with someone's worldview. If there are any negative effects from weed, I (and everyone) should want to know about it first or as soon as possible.

We need more studies on everything to expand our knowledge. But this study compared people who smoked pot and people who didn't. I imagine many of them played video games, partied, or were drinkers. Yes, everything should be studied, but just because something else is bad, doesn't make everything else okay, and this is my main concern with this line of thinking.

My main point is that highly politicized issues cloud science and fact. Another example is climate change. It's just frustrating to see both sides of this argument use anecdotes, logical fallacies, etc, just because something somewhat threatens their worldview.
Any idea if they are switching to using lld as the system linker as well?
Why is El Capitan not getting an update? It's still on support.
Make and most other build systems respect the CC and CXX variables.

Switching compilers is a very common thing among systems developers.. bootstrapping OS builds, crosscompiling for a different arch, getting compiler feedback from another compiler, etc
Much as it irks me to say so, I'm afraid this ship has sailed, at least in American English. For more than half a century, conservatives have been trying to conflate welfare state, and generally any form of wealth redistribution, with socialism. They have succeeded spectacularly, though perhaps not in ways they anticipated, as seen by how broadly popular such redefined "socialism" is among millennials - and how much easier that, in turn, makes it to sell the real thing.
A better example might be Tang versus cold-pressed orange juice, or Wonder Bread versus Dave's Killer Bread. Tang won't kill you, but one is clearly better.

Vanilla is definitely a trick question that exploits a blindspot - tell people about the difference and then ask the question, that's the interesting discussion.

Also, to be fair to that homeopath... their axioms are flawed but disgust at purified sewage is self-consistent with their beliefs ("less is more" and all that). I'd probably refuse too, but on the basis of numerous studies showing sewage treatment doesn't adequately remove pharmaceutical waste.
I worked at Adobe near the Flash team back in the day, and the PMs I knew would have absolutely loved to open-source the Player. The problem isn't willingness, it's third-party code, of which there is apparently a lot.

If there was just a button to be pressed, Adobe would have pressed it circa 2010. But at this point, I think open-sourcing Flash Player is the kind of thing where the project to figure out what all would need to be done would cost more than Adobe would want to invest, never mind actually doing the necessary work (both engineering and legal).
"Time to get rid of Flash" sounds more like irrational attitude than anything approaching positive evolution of technology. We are meant to push technology forwards, fix it, make it better, find the positive aspects, not get on high-horses with brand-loyalty agendas about what should die and what sucks.
If you really are brand new to the working world I would give it time before looking for solutions to a problem that might ease with time. Soon the newness will wear off and you'll become proficient at the admin portions of your job, if not the job itself (solving problems). The reality is that as the newb on the job you are probably focused and engaged the whole 9 hours onsite and that is exhausting as you have discovered. Have you ever watch kids play at a party or BBQ? They are all riled up and running around at full speed and overly stimulated for 5 or 6 hours. Ask one of their parents and they will tell you -- after an event like that the kid will crash hard and sleep like a rock that night. You are in the same boat. In time you won't have to be fully engaged like that for 9 hours and the remaining mental power and energy will be available in the evenings and weekends for hobbies, family & Etc.

You are like the college football players who make it to the NFL and are used to 8-10 game seasons which in the NFL (including preseason) doesn't get you through the half-way point. You are working for a living now and not in Kansas anymore so it might take some time to adapt to the ebb and flow of life.

That said, it is important for the long term to make your health a priority. Unless you have a child, do not compromise that 7-8 hour sleep because in my experience sleep is one of the most important aspects of good health. Is that 7-8 hours of quality, uninterrupted sleep and do you wake up feeling refreshed? If that is not the case you need to investigate. Another concern that I notice in your post is that exercise makes you tired and that is not normal for someone (presumably) in the mid-twenties or even thirties. Unless you are extremely out of shape exercise should make you sleep better, think better and have more energy. Even if you are out of shape at your age a regular exercise routine should very quickly pay much bigger dividends in energy, sleep and general well-being. I highly recommend you pursue that lead and get doctor's evaluation to rule out any problems and start exercising as a life-long habit.

Finally, contra all the other's advice, I would kick the coffee/caffeine or any other stimulants to increase your "energy" (except on an emergency basis). Also, I would limit any alcohol to "relax" because if used more than occasionally the consequences to your well-being are bad. I recently quit drinking coffee and it has really improved my sense of well-being and quality of life. I think all these drugs are detrimental if used daily or even regularly -- they lose their effectiveness and have net negative impact on your capacity to function.
Check out our latest project BlockSchool, we teach programming to kids using a Scratch like programming language in a Minecraft world. Happy to give you a demo!
>Source?

The bottom half-dozen comments on this article?
I'm thinking back to my graduate thesis project, in physics. I started with a fairly nebulous problem, and went down a lot of blind alleys before I finally got something working. And there were some unexpected results that we didn't even have a good way of describing until we saw them happen and puzzled over them. I published a few weeks later, and my advisor moved to another university a few weeks after that.

A rigid rule of pre-registering "study, methodology, and hypothesis" would have prevented me from even launching the project. At the very least, I would have had to register a formal study after my results were already established to a decent degree of confidence. It would have been wasteful and redundant, not to mention risky, since anything can happen to a grad student to prevent them from finishing a degree (illness, loss of faculty advisor, etc). At best, time is money for a grad student who wants to get out of school ASAP and start earning a salary.

My project produced a humble but solid result, and launched a new research program for my advisor, that bore fruit for another 25 years.

Now, I wasn't doing a "study," as in a life science study looking for a statistical correlation. I reported no p-value. So maybe it doesn't apply to all kinds of scientific work. And I appreciate the need to restore come kind of integrity to the medical and behavioral sciences in particular. I don't know how to help those fields, and maybe pre-registration only applies to them. But I'm concerned that declaring rigid rules for science across the board will have unintended consequences.

Edit: Another issue is a student getting "scooped," where some other lab reads the plans and rushes the work to completion. There are labs in chemistry and biology that are notorious for doing this. If a student doesn't at least have an informal guarantee of priority over their own work, they won't take the risk of launching a project in the first place.
I have working for around 7% and my 100% savings sit in PPF, FD and now recently started in NPS.

I really never felt comfortable with any service with which I can have complete control and freedom to transact. I had tried IIFL back in the day and after 3 months putting decent amount of money I wanted to sell some SUZLON shares one day when the price was at 5x of what I had bought at. Transactions failed, kept failing throughout the day. 7 days later I got a one line response saying it was a glitch. Exited after few days and closed the account. Never went back to trading again.

I mean I see the numbers and % of returns I will get but how can I trust the industry where interfaces, that I want to be in that industry, are so unreliable.
> Technology is not a goal. Nobody cares about which programming language you are using, nobody cares about which frameworks your team has chosen, nobody cares about how elegant your data structures are and nobody cares about how good is your code. The only thing that somebody cares about is how much does your software cost and how much revenue it generates.

This. Technology doesn't matter, if your code doesn't fulfill a mission.
Some reputable links.

http://news.nationalgeographic.com/news/2007/05/070521-sex-f...

https://www.scientificamerican.com/article/estrogen-in-water...

http://www.newsweek.com/female-frogs-estrogen-hermaphrodites...
Imaging Reveals Medieval Manuscript Hidden in Book Binding
We started our own browser-based project that teaches kids how to code in a Minecraft like world. Check it out, it's called BlockSchool. We're using WebGL and WebRTC with dataa channels, along with modern ES6 JS + Golang for our stack.
well it would be hard with marijuana leaf. But you could have a vaping placebo, and compare that with vaping the real thing. Maybe the vaping placebo material could be made from marijuana but with the cannabis removed. I don't know enough how marijuana works, tbh, but something along those lines.
Yet another mainstream news report on CRISPR before any scientific report is available.
Should tyrants really be praised for slightly moderating their tyranny? Ireland was happy and agriculturally productive for millennia before the Tudor Conquest. That the Plantation of Ulster was a slow-motion disaster, makes it no less a disaster.
ZFS works work containers and works well with docker.

ZFS is really really amazing, beyond the SAN. It's fantastic for both desktops and servers.

The lack of adaption is problematic, but I use it for all sorts of things.

Like mirroring snapshots between prod and qa, including the database and assets. I can test complicated software upgrades or database migrations quickly and repeatily. This is not something docker can't do by itself.

Much of the stuff I do with ZFS I can now do with btrfs, but ZFS is just so much nicer to work with.
Does this study tell us anything about the reason for the fall in grades? Can we assume it's due to "distraction" or is it possible that there is a detrimental effect on learning ability? It's a big cause for alarm if the latter is true.
Also, you can be nice to people without pretending to feel happy all the time, such as by smiling or singing. Being nice could mean efficiently executing their duties.

I'm not sure why talking about emotional labor, smiling and singing, suddenly brought on doubts about decency, niceness, and assholeness in the following reply. I see that as very stressful expectations to have for somebody.

Smiling is a communication of internal feelings. It puts pressure on me as the customer as well when I know my mere presence is an on-button for an emotional act for people. How draining for both parties.
The similar complexity with weed is that you push people to find it through illegal channels, dealing with drug dealers of various levels of severity
right meaning that they potentially lose out on valuable ad targeting data this way
JS doesn't have a reasonable patch and release cycle, so it's always going to be a chore to try to keep up with discoveries and best practices. The noticeable uptick in releases for other languages are why it's such a joy to work with living languages, instead of the twisted JS world of half-measures and fallen-behind code.
In my experience this isn't happening.
Notice how I never once said I agreed with the argument. To be honest, I don't know where I stand on this and likely fall somewhere in the middle, though that middle seems a bit unclear.

The slippery slope argument isn't invalid in all cases, but I would say it's quite a stretch here considering the argument I presented already exists in civil court in the US.