skysight-inc/HackerNews huggingface dataset:
That isn't true. Feel free to tell me what the alternative theories that constitute competition to abiogenesis. The alternatives are pretty much 1) a deity or 2) some mythical life force assembled things.

Abiogenesis has a ton of evidence behind it, but we do not have the entire chain of conditions and reactions required to go from primordial molecules to actual fact. Much in the same way that 'AI' vanishes, as we develop evidence and establish facts that support abiogenesis, they become standard biology, chemistry or physics.

Compare the argument for abiogenesis in the 1800s to the one today. We've discovered the mechanism for generating our species from single celled life forms, we've determined that RNA have intrinsic catalytic ability, we've developed robust theories of non-equilibrium reaction processes.

As for your statement about junk DNA, you have a very limited understanding of what that actually refers to. Junk DNA refers to non-coding dna. We know those areas can influence chromatin structure, contain regulated control sequences which influence gene expression, contain splicing sequences, etc.

As for your last paragraph, you make it very clear you don't understand the subject you're talking about. I suggest doing more than reading pop science books and picking up a volume on molecular biology. It will clear up what I imagine are a legion of misconceptions you have about what we know.
By this criteria, wouldn't this make art of an artist (fractional ownership) sold by an art dealer a security and therefore subject to SEC registration? Basically tokens are a security because the SEC says so. I haven't seen a good explanation otherwise.
How are you controlling for competition?

https://en.wikipedia.org/wiki/Elbasvir/grazoprevir
A Jupyter Notebook magic for browser notifications of cell completion
You haven't spent much time in /r/trees. If there's a nutty belief about weed, more than a few somebodies there buy into it.
Encryption didn't make it in? That's too bad!
There can be no opinion so wrong that no one will hold on to it.

https://www.quora.com/Does-smoking-weed-help-studying
What I'm getting from your comment is that they're switching everything over to building with clang, including the kernel. That's interesting (it's a bold move) since there have been a few systems over the years that set aside a separate compiler just for building the kernel.
My comment was very clearly asking about the "American manufacturers" part of the quote not the "Made in USA" part.

Foxconn has factories around the globe but they are a Taiwanese manufacturer not an American manufacturer, they are traded on the TWSE:

https://en.wikipedia.org/wiki/Foxconn
Crazy things happen when one abandons his projects.
Why not let components catch their own errors?
For some reason, I think parts of this writeup were debunked, but it's still one of my favorite reads:

http://faculty.up.edu/lulay/failure/vasacasestudy.pdf [pdf]

Thank you for reminding me about the Vasa!
if you just started full-time, it IS an adjustment. give it some time to see how you adapt before you start panicing about having no energy left for other things.
Students don't go to prison for smoking pot.
Humans: still acting like humans, film at 11.

It also shouldn't need saying that this is hardly unique to pot. Also, it won't change. How many millennia have been spent since someone figured out fruit ferments into something that makes you feel good? And yet people continue to slide into alcoholism every day, in every culture. Even the ones where it is illegal.

That said, sure, I can see a temporary effect where legal pot is "new" (really, very old, but that's a different discussion), and so trendy, and the media feedback-loop kicks in so certain kinds of parents have something vaguely novel to upset themselves with. We'll be past that in a generation.
this worry is not a fringe concern: https://www.edge.org/response-detail/26714
True, but there are many open-source wi-fi drivers out there already. Unless broadcom's implementation is something out of the ordinary, releasing their driver doesn't really change the game.
I built an internal tool where teammates submit some details and a fairly computationally heavy data processing task run and posts the summarised results back to a slack channel.

I use containers for this, because it's a really easy way to really quickly get access to compute instances (which vary in size from like 4gb ram to 100gb+ of ram depending on what the user submitted) really quickly and for really cheaply because I only pay for the time it actually runs, rather than renting out an EC2/VM instance all the time (which would either be underpowered, or end up costing too much), or build some frankenstein-ian thing to dynamically provision and spin up EC2 instances on demand, set them up and then shut them down/terminate them once they finish.
In the future, every dissertation will include in its Acknowledgements section, the student's parents, faculty advisor, and gene editor.
Does anybody know if you can take the pot out of the cafes or if you have to smoke it there? I wonder if it's not less pot smoking but less going out.
> many people take weed to relax or relieve anxiety and believe that those things are helpful for their studies

They believe it's helpful to their life in general, which this study isn't measuring. Nobody in their right mind smokes weed to improve their GPA.
> If that were the case, most people in this thread shouldn't be posting (arguing) but personally running their own medical trials. Any other source would in some way require trust in that source's credentials.

We're not discussing the study but logic, so that's really not germane.

> It's also to save time in evaluating claims like these.

You can save far more time by ignoring them.
BPA is apparently easily absorbed through the skin. For example: http://blogs.edf.org/health/2014/10/23/more-than-skin-deep-h...
Physics is a lot more than just fundamental physics. H-Bomb designs for example get hundreds of hours of super computer time to simulate a few pounds of stuff for 1/1,000th of a second and even then they are approximations which need to be validated.
We get it you vape.

Seriously though, I don't get what we're supposed to take away from your statement. Your guess that there might be something worse than weed? Just because weed causes less problems than something else doesn't mean it causes no problems.
My five-year-old Samsung S3 for Verizon stopped receiving updates less than 2 years after its release. The bootloader is locked tight, so I am unable to install any custom ROMs such as Lineage OS.
I was going to post something similar to xenadu02's, but logged back on to find his post already there, so let me tackle a different point.

The simplest bacteria today are amazing organisms. They have cell membranes, which separate the protoplasm of the cell from the outside the world, and only selectively let some molecules through. They contain a blueprint to produce catalysts for a variety of chemical pathways; they can store energy in chemical form and use that energy to catalyze these reactions. The can break down complex molecules into simpler molecules and reuse these building blocks for their own purpose. They can move, to seek out new food sources. They can produce toxins that interfere with the chemical pathways of other cells, killing them.

But when we talk about abiogenesis, we aren't talking about the spontaneous generation of a cell. We're talking about the spontaneous generation of a single molecule, or a small set of molecules, probably proteins (amino acid chains) that, in the presence of proper raw material (amino acids) will tend to act as a catalyst for the formation of more of itself.

That's it; the reaction does not even have to be fast or obvious, even. If it takes years for the molecule to catalyze its replication, that's fine. Everything on top of that comes down to evolution, the slow development of a new trait - cell ways, a genome separate from the cell machinery, the ability to metabolize organic molecules into raw materials, locomotion - over millions of years.

So in addition to xenadu's point, there's also this: the abiogenesis of new self-replicating molecules could still be happening today, and we'd probably never know. The objects in question are too small, and the time scales involved are too large.
Machines with Brains: Being human in a world increasingly filled with robots
This was controlled for by the native students, who also experienced any improvement in the city's environment, but did not experience the ban.
Hi le-mark,

Thanks for the feedback. I realize you're right about your last point about the industrial revolution.

That was totally my fault, I didn't intend for people to take that literally but I wrote it in a way that made it sound literal.

Since that was only an introductory statement I decided on removing that based on the facts shown here later in other to avoid deviating from the post's main subject.

Thank you very much for sharing your thoughts!
CVS works for them, so they keep using it. The devil you know, etc.
The question is - what are your priorities in life?

I'm sterile, I will have no biological descendents. yet I have an increasing number of children and grandchildren. On the day I got married, I became a father to three boys, 6,5 and 3. Within 2 years, I became father to a 13 year girl. As time has gone on, three of them got married, so I increased to 4 sons and 3 daughters. In recent years, that has changed to 5 sons and 4 daughters, and 5 grandchildren.

It is all a perspective of what is important. Financially, life has had its ups and downs. There have been many health problems along the way, extended family conflicts, etc, etc, etc.

Would I change any of it. yes, in all the areas that I could have done better by my wife and children. But otherwise no. As my wife, children and grandchildren have made life incredibly exciting. Even with an autistic grandson and the problems that autism brings, I wouldn't give that up for anything. Not even to have him not have autism.

Life brings many challenges and we grow through them. Work is a minor part of life not the major event.

But the funny thing is that knowing God (Father, Son and Spirit) personally is the very thing that has rounded out, completed and made my entire life with my family worth every problem, trouble, difficulty, disease, cancer, accident, death and misery that has happened.

I have hope for now and the future, irrespective of what may be happening in the world right now.

So I'll go back to my question - what are your priorities in life?
> How about electronic publishing? Try reading a book on disc. At best, it's an unpleasant chore: the myopic glow of a clunky computer replaces the friendly pages of a book.

In context, he's talking about reading books on a computer with it's CRT screen and he's correct. It wasn't the internet that made eBooks viable, it was computers coming in better form factors for reading. The internet was just the delivery mechanism.
These might get you about half way there:

https://github.com/znort987/blockparser

https://web.archive.org/web/20161027122545/http://compbio.cs...
No. You are still reliant on the Arc which is kept on a slab outside of Linux's traditional page cache.
Wondershare Dr.Fone for iOS 8.4.1 Crack Full Version
The sole reason I don't smoke pot even when my friends are to is because in addition to my existing ADD, my memory span on pot is diminished significantly.
But anti-weed will make you better at studying: https://en.wikipedia.org/wiki/Rimonabant (nootropic but can cause suicide, CB1 inverse agonist)
It's interesting that this is a case where React does need to somewhat reinvent the wheel. The best aspect of JSX is that you can use native JS constructs. So instead of a custom HTML attribute (e.g. ng-if in Angular, v-if in Vue), you can just use a JS if statement.

It makes me wonder what a UI language/system would look like if it were designed from the ground up to be declarative. Would it end up just looking a lot like React?

Anyway, this looks useful. Error handling is one of the harder aspects of programming in my experience, so I'm glad this exists now.
Your link proposes that we will be able to manage mutations using genetic engineering.

Parents could choose to have children created from their healthiest genes, rather than leaving children to be shotgunned with a random and increasing fraction of damaged genes. Genetic repair would replace the ancient cruelty of natural selection, which only fights entropy by tormenting organisms because of their genes.

The concern espoused above is that we won't be able to fix the problem.
Alabama's mad cow had an unusual form of the disease
> That seems unlikely of lifeforms arising from independent abiogenesis events.

Not at all, you're presuming there are many different ways life could work, that might not be the case at all. It's entirely possible there's only one or very few possible recipes for life so no matter how many abiogenesis events occur, they produce the same kind of life.

A simple analogy, wood burns, fire is fire, you don't expect every different occurrence of fire in nature to produce a new and incompatible type of fire. Life could be the same, it could be that anywhere carbon based life forms it's basically the same basic recipe and thus biologically compatible with all other forms of carbon based life.
If the exchange doesn't know its customers and doesn't keep logs then it might be successful.
I don't think you can make a very strong argument for the "west's historical scruples wrt genetic editing and eugenics" when you look at the prevalence of convenience abortions and the history of eugenics in America.
>Russian National And Bitcoin Exchange

So nothing will happen to the site or its owner, other than maybe they won't be able to transfer out USD.
Actually if there is a good emulator, I'm happy.
Uber (and presumably Lyft) does the same -- the theory being that they can destroy taxi businesses, then set their prices at anything less than a towncar service.
Google's Project Zero has found quite a number of Microsoft bugs. Unfortunately, Microsoft has not reciprocated the favor.
Autonomous Shuttles
They've already had the Greek cops go pick up the said Russian National.
They've already shown off the one person offices, there will be lots of them.
I just want to buffer a little bit what you said about "the p-value is just checking a box more than being used as a tool for discovery.", but we are likely on the same page.

Sometimes, it is necessary to use a significance test in order to convince the reader that your conclusion based on your interpretation of your observations is sensical, which would be "checking a box".

Other times, and as a frequent reviewer I do see that, infrequently, but still, where the authors see something where the only thing to see seems completely anecdotal (small N, large or fake error bars, no significance or ranking test), or to support their innacurate interpretation of a phenomenon (I see that with young and inexperienced graduate student in a young and inexperienced PI's lab). In these cases, having a proper experimental setup, sample size, and analysis, is part of the discovery.

At the end of the day, it is important to make sure that science stays evidence-based and statistic is one of the tools that can assist, but only assist, in doing that.
As if there wasn't enough inequality in the world, now the rich will be able to afford to make their offspring genetically superior to everyone else's. Have fun with a 1% that are literally overlords.
Winning Strategies in Multimove Chess (i,j) [pdf]
Skip your dinner break, no-one needs an hour, have a sandwich. Get home for 3, have a power nap, till 3.30/4 you'll be fine for the rest of the day.
I totally agree with the article, but i also find it ironic because this guy got his platform speaking at conferences which IMO as the root of JS fatigue.

If we didnt have JS conferences we wouldnt have the level of hype that goes into the next-new-shiney-thing. We wouldnt have a platform for companies to sell ideas and platforms to programmers that they dont need, and we wouldnt have the blog posts and opinions of people who go off to create new solutions to old problems etc etc

I totally agree JS fatigue is just another facet of capitialism. You are a programmer, and just like in the gold mining days, the people who got rich were the people spruiking wares to the miners.

Just like how Apple tells u, u need an iphone to be cool, the JS conference tells u, u need a framework to be cool.

And the key thing to remmeber is - dont beleive the hype. read the code, and make an informed choice. Every dependency in your project should be treated like a matter of life and death.
I bet not consuming refined sugar would help, but there's no way it would help more than not consuming marijuana.

At least for certain subjects. If you're doing fine arts then getting high is almost mandatory. If you're studying math or anything that uses math then getting high regularly will significantly degrade your performance.
IANAL but I'd assume it is hard to argue that there is a common expectation of profit when purchasing art, even though this is why some people buy art. Furthermore, the profits you would make upon reselling the piece of art are not coming solely from the artist's efforts. The artist got paid for their efforts and your profits are coming from your ability to market the piece and negotiate a better deal. In other words, you have some control over how much profits you gain and the artist is out of the picture (ie. they are no longer spending effort to help you make profit).

But a securities law expert would have a better explanation
It's sad to see such a brigade of hate/insecurity around any pot study. It's a shame. Every time there is some inkling of negativity the panic sets in, they criticize the study (which is valid, but how often is the criticism valid), they bring up how alcohol is worse, when this wasn't even a comparison to alcohol.

Marijuana should absolutely be legalized. But we can't just ignore its effects. I get it-weed helps a lot of people out, and it isn't that bad of a drug. But you can't just simply dismiss everything that you don't like that comes out.
Yikes. I wouldn't recommend working or studying on it, but I think it has it's place, like before a yoga session.
Small, Effective and Powerful Gaming PC
> And yet people continue to slide into alcoholism every day, in every culture. Even the ones where it is illegal.

This is a strange thing to "even". You'd expect alcohol to be illegal where it was more of a problem, not where it was less of a problem. In cultures where nobody succumbs to alcoholism, why would alcohol be prohibited?
I believe it. However, there's more to life than squeezing maximal efficiency and productivity out of human beings.
That's a good point, if the drinking age was moved to 25, I think it'll be a bigger effect
Fairly simple (if this is like the other programmatic headless browsers) to make a request through a proxy.
Though this work may seem exciting, there is an existing, respected body of work available on how to mathematically structure a search over a large parameter space and how to mathematically interpret experimental responses. That body of work is a subset of applied statistics called design of experiments. It helps scientists avoid the common failures that result from doing exactly what was done here, random space exploration and non rigourous evaluation of results.

For this to be exciting I would expect some indication as to how this method extends and enhances the existing science of experimental methods and the trade offs involved with using their method. I dont see that.
Seconding an earlier post in thanking you for your perspective on these results.
Is this necessarily true though? Abiotic synthesis of amino acids is a thing. Might Organism T1 and Organism T2 still be composed of similar basic building blocks, even if they don't share organic ancestry?
Interesting. Bitcoin stolen from Sheep Marketplace also ended up in a BTC-E account.

https://www.reddit.com/r/SheepMarketplace/comments/1t0ueq/sh...

https://www.theguardian.com/technology/2013/dec/09/recoverin...
Unfortunately it is not the same...
New GPU Profiler from AMD
"my eyes were brown when I was born, and here's a random string: fd0987as0fh98a0b89safhsa"
Conjure-up dev summary highlights: screen ordering and improved deploy
>So nothing will happen to the site or its owner

"Defendant Alexander Vinnik Was Arrested in Greece to Face Charges in the United States; Bitcoin Exchange Alleged to Have Received Deposits Valued at Over $4 Billion" - article subtitle
As for powertop on Linux, on FreeBSD you have powermon (from Ports):

# kldload cpuctl
# powermon

Intel(R) Core(TM) i7-2640M CPU @ 2.80GHz
(Arch: Sandy Bridge, Limit: 44W)

4.98W [=======> ]

Package: Uncore: x86 Cores: GPU:
Current: 4.98W Current: 3.34W Current: 1.44W Current: 0.21W
Total: 14.37J Total: 9.79J Total: 3.62J Total: 0.96J

Also for power management, powerdxx (from Ports) is better then powerd:

/etc/rc.conf
powerdxx_enable=YES
powerdxx_flags="-n hiadaptive -a hiadaptive -b hiadaptive -m 1600 -M 3000"
In college I was a residence hall advisor in a dorm that was advertised as being more studious, including a zero-tolerance policy on alcohol (students could be kicked out if seen even holding an empty beer can). I'm sure the grades in the dorm were higher, but hat dorm tended to attract students who were going to be more studious/less drunkenly already.
A "good way to start a dialogue" is by starting with a trick question and likely putting the other person on the defensive?
> It's entirely possible there's only one or very few possible recipes for life so no matter how many abiogenesis events occur, they produce the same kind of life.

Presumably this is even MORE likely if the independent lifeforms both emerged in similar physical & chemical environments.
The UK and Ireland are (currently) in the EU and it's not uncommon for English-speaking organizations/individuals with a particularly internationalist perspective to use the .eu domain.
The website still says "down for unscheduled maintenance"
Interesting to think of this as a highly inefficient welfare system for the electoral college.
Late Capitalism by Ernest Mandel: https://www.versobooks.com/books/612-late-capitalism

I haven't read it since undergrad, but he broke up the stages of capitalism in three parts, with the earliest being a free market capitalism up until the mid 19th century, then monopoly capitalism up until around WWII, and late capitalism following that era. It is dominated by a pervasive industrialization that is fairly unrestrained by national borders and a global culture centered around mass consumerism.
Nothing is absolute - I'm a medical user (with anxiety/ADHD/depression) and it's been a complete lifesaver for me, working where pharmaceuticals did not. I did not respond well to traditional stimulants (they only made me more anxious and racy) but medical cannabis is literally the only reason why I was able to function through my PhD program which I had completed two years ago at a top-tier U.S. institution.

FWIW, I am very selective with my strains - only certain types actually help, and my dosage is mild enough to not have strong psychoactive effects (higher CBD-strains). Medical cannabis has truly had a significant impact on the trajectory of my life.
The only time I experience any wobble at all is at the highest height, and even then it's minimal.

My second one was purchased used on craigslist. It is more than 3 years old, and still "like new".