skysight-inc/HackerNews huggingface dataset:
Well, the flipside is that if you stop chemo, the damage to your body stops.

But if the immune system over reacts, it can run out of control and kill you.

I have a relative with stage IV melanoma. She was included in a research trial that used a pair of immune stimulating drugs in an attempt to get her own body to fight the cancer.

What they didn't realize is she had a latent, undiagnosed autoimmune condition called vasculitis.

Unfortunately, while vasculitis is normally isolated to a particular part of the body, hers was systemic. What followed was an immediate halt of the drug regimen and massive doses of steroids to get it under control. If that hadn't have worked, it would have killed her. Full stop.

The condition is now fortunately under control, but she has 30% kidney function, and the steroids pushed her over to full non-insulin-dependent diabetes. She's now on a targeted therapy that, for now, has pushed her into full remission, but it's only a matter of time before the melanoma becomes resistant to the drug.

The reality is, doctors do not fully understand the immune system. Period. These treatments are in many ways astonishing, but they can turn frightening very very quickly. And they don't always work, either.

Unfortunately, there are no miracles, here. Not yet.
I thought the same. If if was genuine, he would suggest another option: starting a small/medium business in tech. You know, a business that helps you escape corporate life, and make money for yourself in the process.

Only problem: there is no way for YC to make money off of it...

So let's ignore S&M businesses in tech and as a valid entrepreneurship route. Let's pretend that the only options are a startup or corporate life.
How is rolling back transactions that are clearly part of a robbery a bad thing?
If you care about anonymity because you're, I don't know, some sort of dissident, then the kind of anonymity offered here is absolutely useless.
> Transferring "value" for goods and services is really more of a social problem than a scientific/engineering one

Do you mean on the margin where there is debate about the contract or whether the goods/services were rendered adequately?

Cryptocurrencies don't attempt to solve this problem at all, they simply allow for efficient moving of currency between parties without the need for meatspace regulation/trust to do it.

Smart contracts make sense with a blockchain because now humans can agree on specific contract behavior that is fixed due to the highly prescribed way a VM will process it. This doesn't mean that humans will or should blindly trust a smart contract to do what some third party claims it will do.

But unlike meatspace, there is one VM that matters, contracts and oracles can earn a reputation as being trustworthy, and established patterns can be executed with incredible efficiency and fairness.

The issue that presents a challenge for all systems (cryptocurrencies and meatspace institutions) is bootstrapping. Some people will get burned in the beginning because fraud will be temporarily easier to commit. This is why I wish the DAO had just been allowed to die without the hard fork. What is needed is not innovative crowd funding schemes, but additional trust and vetting infrastructure.
In most cases yes, but isn't ethereum all about "the code _is_ the contract"? If you as the owner of a house put an ad in the paper saying "if you can manage to enter my house feel free to take whatever you want", should you complain if someone did exactly that?
0x0 (since this thread has hit the reply depth limit): The filesystem on iOS isn’t exposed to users, so I would guess that Apple considers it a strictly developer-facing change.
I assume for critical rolls (edit:roles) you also sacrifice small animals? Just as effective as talking to the dice!
It got patched after he posted this. Before that there was no only_uninitialized.
I was diagnosed with cubital tunnel (tennis elbow) after a multi-month stretch of intense coding. I became seriously concerned when I started feeling needle stabs in my hands at random points in the day. Doctor told me I needed surgery. I managed to dodge that, but it wasn't simple. I had to commit to paying attention to my hands 24/7 for months. Once I made up my mind, it wasn't really hard, just continuously inconvenient.

Here's what it involved:

Self-massage and stretching before, during after typing and throughout the day. Mostly improvised, but this video "Essential Hand Stretches For Guitarists" https://www.youtube.com/watch?v=TSrfB7JIzxY helped a lot.

One keyboard on my desk, another on my lap. One mouse on my desk, another below the desk on a pedestal on my left-hand side. Constantly switched between them to cut down on repetition.

Hunt-and-peck typing with my fingers hanging loose as if my hands were paralyzed. Similar minimal-contact, minimal wrist-effort use of the mouse.

Don't let my forearm rest on anything ever.

Stopped wearing rings or my watch.

Lots of breaks. Lots of getting up and walking around.

It has been 10 years and my hands still don't like typing a whole lot. But, I never typed nearly as much as I did that one year. I haven't had any significant problems since that recovery.
Compare this to a 80s Mercedes 190: https://www.youtube.com/watch?v=gw1GNfA_AnU . The passenger cell remains solid though the crash dummies experience injuries. I often wonder how much better the automotive market would be if solid designs remained in circulation instead of these new-old mistakes re-entering the market every time.
True but there are lots of cases of people exploiting real world contracts (eg. Insurance) to their own benefit. I imagine this is probably a new frontier as far as laws go.
Matt Levine has some thoughts [1] on that matter.

[1] https://www.bloomberg.com/view/articles/2016-06-17/blockchai...
The mossad is usually not a concern when crossing the US border, but when crossing the US border for business and you have company or sensitive data with you or a device that can help get to this data, you can expect the US services will do what is required to get to the data. It's been shown by snowden and assange that the US regularly use surveillance, spying and every tool available to gain economic advantage over foreign competitors.
Various insurance contracts could be applied redundantly and/or recursively, and of course over time the real-world characteristics ought to become known and the price of insurance for well understood contracts should approach free.
> more sites that only work with Chrome (where they literally throw up a page that blocks access and says go download Chrome).

Any specific examples of this? A URL, or a couple of them?

When making such an assertion, it would be nice to minimally provide a way for others to see for themselves.
> What I'm sceptical about is "sex, ascribed gender, and gender identity." being so separate scientifically.

Scientifically, they are (or, rather, gender identity and sex-correlated biological traits) are actually, apparently, fairly related, in ways which seem consistent with the idea that trans and non-binary gender identity is an expression of an underlying non-binary (if strongly bimodal) biological reality, and that ascribed gender based on a binary conception of sex is as poor a match for biology as it is for gender identity.

> Nowadays, it's all about 'identity'.

The three-way divide between objective traits, externally ascribed status, and identity or self-ascribed status, and it's generally importance a in uunderstandinghuman social interaction, is decidedly not a new thing.
Well, the original comment that I excerpted from was discussing the flaw in the very idea of smart contracts superseding human-readable agreements (ie, "the code is the law, and anything we say about the code is just so much noise").

So, yes, in reposting I generalized from "smart contracts are a bad idea" to "Ethereum is a bad idea". Considering how essential the smart contract is to essence of Ethereum, I feel comfortable making that generalization.

Side note: "the essence of ethereum" would make a great subtitle for Drakkar Noir.
A car at least can handle potholes etc. while an overlooked pothole, oil spill etc will bring you to fall (and likely injury) on a scooter.

Situational awareness is a thing, though - especially in extremely crowded traffic.
What are you making in a garage?
This doesn't sound like marketplace disruption as described by Christensen.

Under his model, the marketplace disruptor attacks from the bottom. The challenging product is demonstrably, objectively worse in one or more ways than the incumbent.

If introduced into the US, the Kwid would indeed be a marketplace disruptor. But in India, where the article itself points out that relatively few cars are driven, the Kwid is a luxury item.

In this view, neither anything Tesla has offered nor the Kwid should be considered disruptive. They're both vulnerable to a determined, capable incumbent.
It's completely written from scratch. On top of a typical LAMP stack.
As I said, this law does not mean that you have to accept cash for every transaction. It is often repeated but that does not make it true. Requiring a specific form of payment is well within the freedom of contract.

And Nachname is not offered by every shop, probably not even the majority. If it's offered the usually for a steep surcharge. And while we are at it: Try paying your car tax in cash to the government and you will find it to be absolutely impossible.
How a Corporate Ethnographer Became a Lifestyle Guru
Vendors rush to call everything AI even if it isn't, or doesn't help
That's not necessarily true. It's easy to build an app where you prompt for the user's text input to construct a filename for saving a document/picture for example. NSDocumentDirectory is very much still the recommended place to store persistent user data on iOS. Imagine any non-English speaking person entering a non-ascii name for their document.

As another example, imagine Dropbox.app syncing files from the dropbox cloud reusing explicit filenames into the app's sandboxed Application Support/Library/Documents folders. I have no if they do this but if they do this could spell trouble.

Or simply any app supporting iTunes File Sharing, allowing users to drag files from their mac into the app container's NSDocumentDirectory directly.

Edit: Interested in hearing counterarguments instead of downvotes, thanks? :-/
out of curiosity, who is this judge talking to again? A storage node?
Clinical Study of Fundoscopic Exam of Pediatric Patients Using the D-EYE
The answer to every question is China and India. China is the worlds leading e-car economy. Who cares about a niche product that could not be sold in any other market.

China will dominate the e-car market.

Hint: They will not allow foreigns into China
It's no longer 'very little effort' to get a doctor to write for an opioid.
you are helping Gwyneth Paltrow if this article is true. maybe you work for her i don't know.
it creates such a bad alternative to the current system it's certain not to come about.
because it's hashed... so you can't hack it.
Show HN: Vim plugin for YAML formatting
It's about the structuring of the trust. I trust that someone from the hospital will triage me when I get to the emergency room, but that kind of trust is very different than if there is an online service which does remote triaging when I am on my way to the hospital.

When the proponents of this service are claiming that you don't have to trust the hospital that they would get someone to triage you, instead you can have your own assigned triage Nurse, you're claiming "But you still have to trust that this third party agency will have someone on the remote location to triage you, then what's the point of using this service?"
Woah. That is seriously cool, that we can do that. Congratulations on your recovery, and thanks for going through that for science.

Can you maybe elaborate a little on how they selected the cells to lab-grow? Step 2 and 3, in particular. By what criteria did they divide them between petri dishes and how did they test how efficient they were at destroying cancer cells? (Did they feed them parts of your tumor or something?)
The reality is that for a while, Chrome was simply a better browser. Extensions "just worked", it silently auto-updated (huge for non technical users), was very secure (anti-phishing), it came with Flash, sandboxing from day 1, etc...

I installed Chrome on the PCs of family members and it was trouble free for them. No need to update Flash separately, no random crashes, the anti-phishing is great, too.
Are you sure it need a license ? I were thinking that AXI usage is royalities free (https://en.wikipedia.org/wiki/Advanced_Microcontroller_Bus_A...)
>This shifted liability //

If I user makes a suggestive shape out of lego blocks inside a 3D game, what liability is there? Much less surely than any of the text chat you get on virtually any online game??

Does/had Minecraft ever had a major problem with what one might term "phallo-philes"?
Honestly no, none of them are publishing content that is worth what they're trying to charge. At $15/mo, the NYT seems to be selling a feeling of intellectual superiority more than they're selling better journalism.
It's not labeled as stable, that does not mean it is unstable.
the parameters of justice are contained

It just doesn't work like this.
GitHub Is The Next Big Social Network, Powered By What You Do, Not Who You Know
https://www.forbes.com/sites/anthonykosner/2012/07/15/github...
I don't know if that analogy holds in the context of ethereum which is marketed as "code as law". I think it could be reasonably argued that this individual was fairly participating within the terms of the contract.
About half my day job is auditing Solidity code for startups. And yes this should have been caught.
You don't spend money but you spend your other precious resource which is your private time. With money you can leverage a project by buying somebody else time (employee, partner). Such may be not 1:1 comparison of your own dedication but with fair equity and good match you may get similar drive.
The begging in the comments section, along with their wallet ID's, looks like a glimpse of the internet 100 years into the future.
Carrier iQ demonstrated GPS level tracking of 100m+ phones nearly 10 years ago.
Unadulterated kratom still affects mu-opioid receptors, just as other opioids, and so stopping taking it will cause opioid-like withdrawal symptoms.
I drive both, and any car is much safer than the scooter.

But the scooter beats traffic jams.
I'm not sure if I understand your question. It's still nice to be able to choose who the trusted party is.
performance and self-service are key to analytics and insight .. Dremio makes big data feel small while bringing all enterprise data to analyst's fingertips.
Awesome idea, until an evil-or-just-buggy insurance contract robs its counterparties blind.

We're basically in no true Scotsman territory here.
about 20 years ago foreigners barely speaking english have been sent to US high security prisons with latinos gang members for an indefinite period of time without charge.
This happened to this guy who had a business of super nintendo game genie or something. He spent several weeks in there before he got help from family worried he didn't give any news.
It's like a modern Zombocom.
my favorite part of this latest ICO hack is that it appears to have gone to same wallet as the dao hack .....

Any proof of this?

EDIT: This appears to be false. From https://blog.ethereum.org/2016/06/17/critical-update-re-dao-...

The leaked ether is in a child DAO at https://etherchain.org/account/0x304a554a310c7e546dfe434669c...

But that site shows the account hasn't received anything since July 8.
Nice, though it would probably just cause confusion for a heap of people, and would result in them not installing the app (good) and blaming Google for it (bad for their brand).

I would have thought by now it would be pretty easy for algorithms or AI to pick up on these kinds of tricks, whether by a similarity score or an image processing approach.
> Why not just use a traditional financial institution then?

Insurance via smart contracts is still far simpler and more efficient to implement than in meatspace.

Consider things like insurer solvency risk and the way that meatspace regulations make that hard to understand. With cryptocurrencies an insurer can easily offer proof of solvency based on all outstanding risks.

Insurance emerges as a fundamental economic behavior when you have investment and you have an uncertain future. There is benefit to risk pooling. Since most of us live in the first world where the traditional financial system has evolved ample insurance infrastructure, we don't always realize how remarkable it is, or how vulnerable we are to bad regulation of it.
Oh wow, that was worse than I expected. Driver just gets destroyed.
Yes i agree, would have been more convenent to use the integrated jtag of the FPGA, but i focused on making an universal solution first :)
ASCII version of the classic card game Spite and Malice
My JS implementation is http://dancing-links.herokuapp.com/

It includes a sudoku (also exact cover) and pentonimo solver.
I used Firefox since it was called Phoenix in 2002. Fifteen years. None of my friends or acquaintances used Firefox. I was the last man standing.

I switched to Vivaldi last month due to webextensions breaking fully functional mouse gestures in the Firegestures addon. They finally forced me away. Thankfully Vivaldi exists!
Won't happen. People need to believe that the justice system will hear their pleas and consider factors on-balance, and then proceed in fairness. In real law, there are several potential overrides available to stop egregiously unfair outcomes that would otherwise be legally valid (estoppel, unconscionability, etc.). People will not accept a system that does not have the appearance of fairness (regardless of its actual fairness).

One of the things that cyberpunks fail to grasp is that people don't want a perfectly immutable, fixed system. They want to feel that their sense of justice and moral righteousness can be satisfied. Stuff that drops people off right at "sucks to be you" doesn't really work; there must be some type of recourse available even if it doesn't have a 100% success rate.
Because it's rolling back transactions that were done under "the law" (e.g. the ether contract stuff) by human intervention when the entire draw of the ether contract stuff was the promise of no human intervention
how is a contract mechanism with arbitrarily mutable contracts a good thing?
What do you mean by reply depth limit? I'm able to reply to your comment... :-/
That wouldn't move the money to their rightful owner but to the previous owner.
There is also, IIRC (though it's been a few years since I was last researching this) for many people a limit on the tolerance one builds up (though it certainly gets very high). I recall something about addicts in the Netherlands—which has a program like the one suggested—eventually hitting a stable dose and staying there.
They vouch for bad sites all the time already - that is what the article is arguing.

If a site pops into existence maybe it shouldn't be trusted immediately. Trust has to be earned and this is a protocol to 'earn trust'.

The goal is to disambiguate 'trust' with 'encrypted connection'.
You can't make "Lego bricks" as Lego is the trademark giving the origin of specific bricks but you can make near identical (missing the wording "Lego") bricks if you wish. If you do it at home and completely without any commercial aspect [giving them away can be commercial, so you have to take great pains to avoid being commercial] then you can make identical ones AFAICT.

This isn't legal advice of course.
Microsoft Campus Tours – Reactor Space in San Francisco
I think the capitalization of a method making the difference between two very different outcomes might be my favorite example. It's that kind of stuff that makes me happy I have to go through api reviews at work - although seriously how does anyone sign off on these designs?
>I like how the U.S. Founders tried to approximate a solution: a group of federated states

The Founders didn't design that. The colonies, started by various people or groups for differing purposes, existed long before the Founders were even alive, they just wanted to group them into a confederation for trade and mutual defense purposes. This isn't unique in history at all.

>We eventually should have ended up with 50 separate, concurrently-running, dynamic experiments competing with each other for residents. Our current federalism prevents this from happening, though

We tried this before, and it didn't work. Go read about the "Articles of Confederation", which governed the US before the Constitution was adopted in 1789. It was a disaster; the central government wasn't strong enough to get anything done because the colonies couldn't agree on anything. Not only was this bad for defense from outside invaders (i.e. the British), it was bad for trade because the colonies got into trade wars with each other. You're not going to have a functioning nation when the different regions are at war with each other; just look at pre-EU Europe for an example of what happens when you have a continent full of very small and diverse nations that get into trade wars with each other. It's not pretty.

The other problem with your "competing states" idea is how you handle interstate commerce issues. Without a strong federal government, it's hard enough, but what happens when you have actual cities spanning multiple states, as we have with DC, NYC, Louisville, Philly, etc.? It's bad enough the way we have it now, but in your system it'd be a complete disaster.
According to some other comments, around the $1.5 million mark.
There's only the briefest mention in the OP of NBC Universal being an investor, but it's worth mentioning than NBCU (a part of Comcast) is one of Snapchat's biggest investors, with a $500M stake: http://www.cnbc.com/2017/03/03/nbc-invests-500-million-in-sn...
> allowing you to reconstruct the file if any subset of the nodes is online.

Any subset? Surely there's some minimum number of nodes (>1) that need to be online. Unless each node has a complete copy.
No offense, but I'm not going to base my understanding of how programming language terminology works on Elisp.
The first 15 seconds are enough.

Spoilers, The Versa is totalled, but the driver can probably survive. The Tsuru has the front half obliterated and the crash test dummy's skin comes out.
No airbags on the Tsuru, but who cares, the car body can't survive the crash anyway.
Software May Be Eating the World but Pizza Fuels the Software Business
For the Mozillans around here:

This is sadly almost what I feel.

Then again I'll stick with FF for now since Google has managed to annoy me with their Chrome campaign and since FF is slightly better for my use cases and uses less resources AFAIK.
If you have Prime, I think the Washington Post subscription offer of 6 months free and then $3.99/month after that is a very reasonable value.
Which is the minority opinion of the more "neckbeard" crowd that disproportionate control of the platform.

If it scales to be a relied upon social tool, their foot-down rhetoric would likely come under heavy scrutiny.
Can you rent this anywhere? Don't really have $1.5 million to toss around fun.
Check back in November. Literally all of those things are in progress and scheduled for Firefox 57.
I use the term unpredictable behavior simply to describe a case where the contract has behavior that was not fully anticipated by at leat one user of the contract.

Of course, the code is deterministic and so the behavior was unambiguously defined in the contract's source code.

But there exist all sorts of semantic bugs, which can at times be pretty subtle, which means that even for an expert, the mental model of code execution may not match reality.

If there were nondeterministic behavior in the Ethereum VM that would necessitate a fix to the VM and would likely be completely uncontroversial.