skysight-inc/HackerNews huggingface dataset:
Apple Bluetooth keyboard with those chicklet keys, the similar keys on the macbook, and a heavy,noisy,awesome unicomp buckling-spring keyboard at work to annoy everyone around me. For prolonged use I prefer the buckling-spring - although at first it may seem like you need to type "harder" - you actually don't - the tactile feedback lets you automatically fine-tune your typing to just the right amount of pressure.

Plus it's semi-waterproof (water drains right through it, as long as you don't dump enough in for it to rise above the key silos and get in the electronics) and it can take a beating like no other for those angry typing sessions.
Methinks the free sites doth protest too much. I've used Plentyoffish, Okcupid, and Match.com. Only Match.com was a fraud-free experience. Sure, a paywall induces a motivation for 1st-party fraud, but it drastically reduces the motivation for 3rd-party fraud. Someone who solves both will become a rich individual.

For the record, I met my beautiful girlfriend of two years on Match, so count me as biased. :)
>As others have pointed out there are StartUps with the money, but somehow we still don't hear about orphan drugs with potential to make it burst onto the scene.

Imatinib. It was developed as a cure for CML, a disease which only affects a few thousand people in the US. That's just the most notable. From wikipedia's article about orphan drugs,

"In the USA, from January 1983 to June 2004, a total of 1,129 different orphan drug designations have been granted by the Office of Orphan Products Development (OOPD) and 249 orphan drugs have received marketing authorization."

>Imagine this you are a VC with a $100 mil. to burn will you support a long and twisted development process of something that might not even work at the end?

The fact that pharmaceutical startups exist (google pharmaceutical startup or something like that and you'll find plenty of them) show that VCs, or whoever it is who invests in them, have different ideas about risk than you do.
You can under-volt without reducing speed at any time. With a program like rmclock, you can switch to high frequencies on the fly like a turbo button.
That's not really fair. The government funds more than "development of military technology".
Could anyone please point me to government scientific or technology accomplishments in the last 30 years?
Something that noticeably improved our quality of life.
Something on par with achievements by IBM (Business PC), Microsoft (OS, Office, and other software), Google (search), Apple (smartphones, music, ...), Intel (microprocessors), Pfizer (drugs).

It was surprising to see down-voting just on the basis that you disagree with the idea.
Welcome to groupthink.
The alternative phrase "Ich bin Berliner" wouldn't have fit well into the context

Why not?
I'm thinking a Facebook IPO might change the pace of things a bit. Once they're answerable to shareholders and wallstreet and people that are more concerned about profit than social media, their tune may change slightly. I'm sure they'll do okay, but being a public company and answerable to shareholders does make things different. Recall the outrage when YHOO refused to sell to MSFT, who was offering an above market value per share. No one cared about the well being of either company. Certainly not the shareholders and certainly not wallstreet.
If you calculate some sort of mean aptitude for IT work for each gender, you end up with a meaningless statistic. All men and women are individuals capable of individual contribution and for any large 'group' of individuals to be discouraged/lost is not a good thing for any profession. For selfish reasons I want more women to consider applying their talents to IT/computing.

I'm sure sexism and other factors have an effect, but people have a knack for overcoming things like that... I think the problem is much deeper rooted.

Anecdotal evidence, but ten years ago the pupils in my year at school were asked to pick from Computing or Administration as one of their subjects for the next year. We ended up with about 2 girls picking computing in the whole yeargroup, whereas the Administration class (secretarial work) was much more evenly dividied.

Computing was a harder subject but the girls in my year were just as academically accomplished as the boys (if not more). So what gives? That is the root of the problem IMO
It sounds contradictory, because I think dating sites are yet to reach their prime, let alone having past it already.
Suspicion or expectation of conspiracy can also be due to past exposure to evidence of actual conspiracy. Men colluding against others has been going on for thousands of years if history is to be believed. And yes one common motive to conspire is to gain large amounts of money to the detriment of another group, often involving lies and force. Are all imagined conspiracies real? Probably not. Do some exist? Of course.
Well that's very disappointing. I'm already getting an Iphone, but buying a mac as well would be too expensive/unnecessary. Perhaps there are modified versions of the necessary software to run on windows?
I think I created a very nice feed reading experience with NewsBlur: http://www.newsblur.com.

It shows the original site, allows you to read as you normally would, but keeps track of the stories you're scrolling past.

It also allows you to filter stories based on what you like and dislike about them: words/phrases in the title, tags and categories, authors, and the publisher themselves. There is a slider that allows you to show/hide stories based on this filter. It's very fast, too.

I am writing an iPhone app so you can use NewsBlur everywhere. It's just a hobby project, and people have so far been impressed. But I would love for NewsBlur to become a useful tool that people choose to use.

I wrote it because I was also dissatisfied with readers, especially Google Reader. I also knew Python (Django!), JavaScript, and wanted to put them together to test my abilities.
Crisis for 46 State Governments Facing Greek-Style Deficits
I remember first watching this and being scared. Scared of one day forgetting the last quote in this amazing video:

"Remember when you were a kid, when everything was within your reach, and then say to yourself quitely and with determination, it still is."

I'm 20 today and still think that. But my greatest fear is one day losing sight of that because of a "normal" work or life or family commitment.

Amazing video though, mate. Thanks for sharing.
Palin Stirs Things Up at California State University
Most importantly, I'm writing it all as open source. The iPhone app I'm writing, the feed parser and fetcher, and the front-end reader are all on GitHub: http://github.com/samuelclay/NewsBlur/
The problem is that unless that filtering works magically in the background, it just adds interface debris. And it's easy to reach a threshold there, where just scanning for the stuff to filter (hidden amongst the UI elements) and you might as well be better off doing your filtering yourself.

Which right now works best for me. If I use Google Reader directly, it's set up to use the re-reader style, at home I use NetNewsWire with the subscription list hidden. So to browse through it, I can mostly use keyboard shortcuts, so skipping something is easy. Reading is comfortable enough, but if the article is too long, I either open it in a background browser window or send it to Instapaper.

Works well enough for me, although if I had more newspaper-style story listings in there, that just contain the headlines and link to the main story, filtering and adding to the queue might be more difficult.

And alternative would be some kind of social filtering, but that's close enough to HN or Reddit or just listing the links you've got on your twitter inline (c.f. http://news.peepcode.com/)
Tell HN: My iPhone 3G is unusably slow since upgrading to iOS 4.0
Apps (even Apple apps) take forever to load, and routinely hang while performing simple tasks (typing, focusing on a form field, switching tabs, etc). I'd have to recommend staying with 3.x if you haven't already upgraded.
One useful strategy for avoiding this affect is to move around a lot and to deliberately remain a little undereducated about the things you don't work on. That way, if you ever feel like you've grown too cynical about the field you're working in, you can switch to something else and approach it as a complete newcomer.

Software is used in so many places that it's easy to regain your newbie status any time you feel like you need it again.
People care about privacy, but they become complacent in giving it up. Remember the days when people were too scared to put their credit card into an internet website? Things have changed a lot since then, and it's hardly been 10 years.
Funny how Google was preaching for years how important a fast, and speedy website for success is, and now the largest online multi-player game is triggering 30sec. timeouts. -.-
'There is very little corruption in everyday life - police officers, fire department officers, general government workers - do not seem to take bribes (and indeed they do not). Yet, in upper levels - City Halls, State Governments,Congress = corruption is rampant"

How in the world do you know this? Cops in the US don't take bribes? Really? This must be something that started in the last 10 years, at least based on what the I the cops I've known have told me. (Most cops did not, but certainly some did, in varying degrees.)

And corruption in City Hall, et al, is rampant? Multiple citations needed.

I've no doubt there is corruption at all levels, but assertions of it being rampant need some backing.
are you talking about the current dating sites? really?
Try Fever: http://feedafever.com/
Roughly? The Mac Pro has a workstation-grade dual-socket motherboard with Xeon processors, ECC FB-DIMM memory, and four PCI-E x16 slots. The build quality is also significantly better than most off-the-shelf PC hardware. Granted, this isn't important to most people buying their home system to dick around with, but it IS called the "Pro" for a reason. Go spec out the same hardware from Dell or HP and you'll find similar prices.
>"In the USA, from January 1983 to June 2004, a total of 1,129 different orphan drug designations have been granted by the Office of Orphan Products Development (OOPD) and 249 orphan drugs have received marketing authorization."

Thanks. I realize my mistake now. I meant it as in how many new companies try something as risky as making an orphan drug? I shouldn't have leaped in with a bad example without checking it more thoroughly first.

Sorry.

>The fact that pharmaceutical startups exist (google pharmaceutical startup or something like that and you'll find plenty of them) show that VCs, or whoever it is who invests in them, have different ideas about risk than you do.

My point over here was that they fund them, but they might not fund something as risky as stem cell therapy. As far as orphan drugs and StartUps go; is there an data freely available online on the composition of companies that market orphan drugs?

Perhaps that would be more revealing?

(I found this site from the wiki article http://www.urchpublishing.com/publications/discovery__rd/orp... , but it's paid)
1) Please show me "pretty much everything" that government developed in the last 30 years.
http://news.ycombinator.com/item?id=1465878
2) "Man on the moon" is pretty much useless for us.
3) Government didn't give us Internet as we know it now. Not even close.
Government contributed may be ~1% into Internet (if even that).
Considering how much that contribution costs to taxpayers every year -- government performance looks pretty bleak.
A pro/con discussion would need a more detailed explanation of how exactly you plan to implement this.

That said, some general advantages to having a permanent user-chosen password include:

- The user can login on any client even if they don't have access to their email on that device. In order to accomplish this without a user password, the user has to have their email device and the secondary device present at the same time, and you'd need to give the user a human readable OTP (one time password) they can enter into the secondary device manually.

- Convenience. Users doesn't have to visit their email to click an URL and can instead proceed directly to the logged in experience.

- Are you planning to give users a "log out" link, and then expect them to do the email hurdle each time? That additional email hurdle will encourage users to stay logged in when they might otherwise logout, which could make their accounts more vulnerable to theft. However, if you expect and want users to remain logged in for longer periods of time, it becomes more justifiable.

- For various reasons email delivery can be significantly delayed. It's not as much a problem now as it was in the past, but this lends email usage towards more asynchronous tasks where timing isn't terribly important.

- If you use a good password, it's more secure than email authentication. Remember that emails are basically the digital equivalent of post cards. But if you use bad passwords, like most users do, all bets are off, your accounts (email account included) are highly vulnerable to theft in any case.

- The URLs in emails will need to be designed so that they are only good for one use and time out after an hour. Otherwise gaining access to the email history or browser history becomes a means to steal login state. However, this also applies to the URL authentication that goes on typically in "forgot password?" workflows, so you probably have to do this work anyway.

- Users are sometimes reluctant to enter a valid email address for privacy and spam concerns. Often they will put in a garbage address just to get past that part of the sign up hurdle.

I'm sure there's more to say. That's what I can think of at the moment.
To be clear, enforceability of the EULA in the United States is murky as well.
Reeder on the iPad is spectacularly good.
I use Postrank (formally AideRSS) for this reason - BoingBoing have far too many posts for me to read, so I run their feed through Postrank, and get only the most interesting posts.

http://www.postrank.com/main - their index page is baffling.
مشاهدة مباراة الارجنتين والمكسيك
مشاهدة مباراة الارجنتين والمكسيك
مشاهدة مباراة الارجنتين والمكسيك
I would say it's a combination of a number of reasons, some -- if not all -- relate to the technologies encapsulated in RSS.

First, because RSS by design is meant to just be metadata, and because it's really hard to render HTML (especially those that are not well-formed) the readers typically have to jump through so many hoops to get things just working.

Second, I think it's also because the RSS readers are typically developed by non-designers. Although Google Reader keeps it simple, it's utilitarian and mostly not very pleasant to look at. I've tried others (which are also free) but typically it doesn't come close to making it enticing to read.

Maybe someday someone will do a feed reader that renders articles in a sane and readable way.
Indirectly, yes.

SharePoint integrates impressively well with Word and Excel, for version control and as a data store. Using Office with SharePoint definitely adds value in ways that Office replacements don't currently.

In that way, SharePoint strengthens Office's hold on the desktop, which strengthens the resulting network effect.
Yeah, but the average fast food sandwich contains 28 secret chemicals and 8 hormone disruptors.
I'm actually surprised that no one created a web fronted to either of them yet. Both of them support a multitude of interfaces anyway, so the hooks should be there. Running Emacs as a daemon would support simultaneous GUI and terminal editing too.

Yes, web-based VTxxx terminals would probably suffice, too, but I'd prefer a native interface.

Someone should do a EmacsHub, where you've basically got a little VPS running an emacs daemon, a web interface to it etc.
I haven't tested it, but I'm intrigued by Shuan Inman's Fever reader (http://feedafever.com/). Basically the idea is that you separate your feeds into two distinct types: essential feeds that you read completely, and supplemental, high-volume feeds (aggregator-type blogs, like Engadget). Then the essentials are cross-referenced with the supplementals to see what you're likely to be interested in.

I have a similar strategy, but instead of trying to manage the "supplementals" in my RSS reader, I try to a) identify them, and b) banish them back to the browser where they belong. Identifying them can be tricky, at least for me, because I tend to think that feeds I've been reading for a long time are essential, when often they're not. Removing a lot of politics blogs from my reader I swear has made me less stressed, and I don't feel any less informed.

I think the higher volume of content means we have to become better at selection — not only in choosing what we read, but also in identifying and not reading what is noisy and lacking in substance, even when tempting (ahem, HuffPo). Edit: and I'm not sure algorithms are the solution; I think it's something our generation will have to learn — to be our own conscious curators.
probably didn't. They probably copy/pasted large chunks of assembly in the process of reverse engineering it. The large chunks would probably be what's being referred to as Apple's code.
Great UI, et al.

I also like that it aims to help the user make sense and filter their news sources. But you completely lost me when you were explaining in the video how you edited the settings to see Comics. I'm confident I myself could figure it out with time and effort, but it goes over the heads of the common man, which I believe is who we're talking about now.
The Happy Hacking Pro 2 is great if you like a compact 60 key keyboard. The Escape and Control keys are positioned perfectly for Vim and Emacs, so you don't have to bother with remapping them. Works on PCs and Macs. The price is steep but worth every penny. If I ever go to Japan I'll buy half a dozen and stockpile them. This keyboard is not for everyone, so you should try it before you buy.

http://elitekeyboards.com/products.php?sub=pfu_keyboards,hhk... and http://www.geekstuff4u.com/happy-hacking-keyboard-pro-2.html

I also use a Das Keyboard, a nice full-sized keyboard with a great build quality---but it is extremely noisy and I wouldn't recommend it for that reason only. There is a silent version, too. Knowing what I know now, I'd go for the quiet one. Funny thing, daskeyboard.com sells matching earplugs for this keyboard. You buy a set for yourself and for everyone who works in the same room as you.
This is about cure versus treat. Google is trying to enter the spreadsheet market, not destroy it.

As an analogy Google Docs falls safely on the treatment side of the fence.
I mean anything.. current/old.. the sites which targetted "dating" in specific were never able to succeed, unless the social networking came into picture.I see "dating" and "social network" as 2 different things. How many people actually log in onto a dating site with a hope that they will actually get a genuine date!.I think the number is pretty less. Actually speaking "social netorking" sites generate more traction in the dating world than the actual "dating" sites.
Excellent post.

For every youngin' out to change the world, there are probably two oldsters who can remember why the last, similar, effort failed. But it's quite possible that while one of oldsters will stand in youngin's way, the other one will give him a boost and some good advice. Sure, Brin and Page started Google out of grad school but Terry Winograd added some good advice.
That's a big problem with Apple nowadays.

This has been a problem with Apple since at least 2005 and really since at least 2002, when I started thinking about getting a Mac: they've never sold a decently powered, expandable box.

And it probably will continue to be a problem moving into the future.
I wondered this myself until I hit upon the simple solution of deleting feeds with too low a signal to noise ratio (for my personal tastes). Expecting RSS readers to tease out relevance means having to give them an idea of what's relevant to you. This seems to be a self-inflicted problem on the part of people who use feed readers. I've tended to think I "needed" to follow more than I could possibly consume and retain. Pruning my feed list not only helped with overall comprehension of feeds I'm interested in, but eased a somewhat bothersome feeling that I was falling behind on a keeping up to date.

Personally I ditched NetNewsWire after Reeder for the iPad came out. I have Reeder on my both my iPhone/iPad and just use Google Reader for those times I check feeds on my notebook. The user experience (note that I didn't say user interface) it provides is astounding. Navigating feeds, marking read/favorite, and the article typesetting/layouts are all the best I've seen in an RSS client to date. Combine something like Reeder with a carefully curated feed list and I don't really see there being much of a problem.
- don't even think about running it on the hardware you already have -
only use specifically built systems (such as those linked)

As far as I know, hackintosh works well in laptops. I'm running it on HP Pavilion dv5-1010us. The only hardware I can't get to work is wireless - which is admittedly quite a pain.
Visiting a BP Sponspored Florida Beach Ad place? Take Oil remover w/you [video]
Move to Philadelphia.

Or Berlin.

Vienna's pretty great on a budget, too - that's where I live. But Berlin is cheaper and more "happening" (though Vienna is in every way nicer itself).
What percentage of the technologies that people cite as being made possible by the government were developed for non-military purposes?

Edit: The NSF started out as a way of enhancing military research: http://en.wikipedia.org/wiki/National_Science_Foundation
I couldn't find a byline on the article, but I have a feeling the Playboy interviewer was this guy: http://www.amazon.com/Art-Interview-Lessons-Master-Craft/dp/... .

That book is an excellent read. It kind of startled me to discover that one of the best interviewers I've ever read worked for Playboy. I guess it really is worth reading "for the articles"?
I highly recommend Highcharts. Phenomenal charts w/ a beautiful api.
New Loan Calculator for the iPhone (free version has iAds)
Here's a company that was started in 2006 with the intention of treating rare diseases:
http://www.atonrx.com/background.php

They were just bought out for $318M. Not bad.

Treatments for rare diseases actually have fewer regulatory hurdles because of the Orphan Drug Act, which basically says that there's a lower standard of evidence for drugs that treat rare diseases.

>My point over here was that they fund them, but they might not fund something as risky as stem cell therapy.

Maybe not, but maybe that's a good thing, for reasons carbocation stated.

>is there an data freely available online on the composition of companies that market orphan drugs?

There's a list of drugs here (well, do a search on an empty string and you get a list) and the companies who make them, but it's not exactly predigested.

http://www.accessdata.fda.gov/scripts/opdlisting/oopd/index....
I'm in the wrong business.
Looks like he was the 18th Century Million Dollar Man.
Perhaps you could give some reasons why?
1) I have been working as researcher for the past 12 years or so (cancer and neurobiology). Pretty much everything in the field of medical science is founded mainly by public money: this goes for salary and research money. Private contribution is quite minimal and proximal to zero in basic research.

2) Wut? Do you have any idea on the level of technological transfer that space research brings to your everyday life? This goes from materials that keep your home warm to GPS, really.

3) dude, arpanet is a project of DARPA. WWW is a project of CERN. I got money from DARPA and I study fruitflies for god sake.

You have no idea what you're talking about.
"Blackhole" interpreter in PyPy: new optimization in PyPy 1.3
Energy Saving Javascript