Edit: Nevermind, you said it involved dietary change to handle acidosis. That's great, but is it related to the bacterial problem?

Sorry, I missed this earlier.

If you look up studies on biofilm, there is a connection between acidosis (and/or inflammation) and antibiotic resistance. Reversing excess acidity leads to patients becoming sensitive again to a larger variety of drugs.

But there is a lot more to my dietary changes than that. Mucus is a really significant part of the immune function and people with CF have very salty sweat. My view is that sweating out salt at high rates also drags other minerals with it.

The standard wisdom is that people with CF "overproduce mucus" and are "drowning in their own mucus." One study found that we underproduce mucus and I believe this is the accurate interpretation for reasons I have outlined somewhere on my blog. I can find it if you really want to see it.

Salt is a major component of mucus and when you get people with CF producing proper and healthy amounts of mucus, it reinstates a portion of their immune system that is typically down. I consumed a particular brand of salt high in other minerals for some years. It had a significant positive impact on my health. I also lived near the ocean for a few years. There is a non drug CF treatment where they nebulize saline solution. It grew out of the observation that people with CF who surfed had better outcomes.

CF is not really just a lung disease. That is sort of a misconception. It involves all the mucous membrane systems, including the gut and the reproductive tract. Malabsorption, difficulty gaining weight and Cystic Fibrosis Related Diabetes are major elements. Men with CF usually lack a vas deferens, thus are unable to father a child without intervention. Women often also have fertility issues.

The gut is about 70 percent of the immune system. So addressing the gut issues in CF is part of addressing the immune system dysfunction.

The gut gets incredibly out of whack with CF. The high use of antibiotics in patients with CF very often leads to e coli infections. This is often treated by removing the large colon. This is, horrifyingly enough, one of the more common surgeries in the CF community. There is a reason it is called a Dread Disease, and it isn't just what it does to your lungs.

I have also read up on some of the current research into the gut flora. I think the terrible state of the gut and the gut flora is a really major element of the immune problems in CF.

You might be interested in the articles on stunting linked in this post on my blog: http://miceats.blogspot.com/2016/09/jalapeno-with-pepperoni-...

The blog isn't intended to be easily legible to an outsider as a serious work on the immune system. There are two reasons for that. I have been harassed by too many people, so I don't want to position it as a medical blog. It is intentionally framed as a food blog. Second, I want it to be approachable by lay people.

The general format is to talk about I have x issue, I am choosing to eat y food for z reasons. I don't always manage to explain my reasons in every post, in part because it gets very, very repetitive. I eat many of the same things over and over for weeks or months for the same reasons. So, the back story on my thinking is very scattered throughout the blog and hard to find. That is partly on purpose.

Best.