skysight-inc/HackerNews huggingface dataset:
There's a huge difference between "wages should be higher" and "it should be illegal to pay low wages". Like, this is the difference between "people should have housing" and "being homeless should be illegal". Outlawing a thing does not fix the economic forces that generate it.
While ATP may help to solubilize proteins, I don't find it surprising the cells under question have very high ATP concentrations. I take issue with this statement:

> In addition to being an energy source for biological reactions, for which micromolar concentrations are sufficient, we propose that millimolar concentrations of ATP may act to keep proteins soluble. This may in part explain why ATP is maintained in such high concentrations in cells.

Sure it's important for neurons to prevent amyloid-beta from aggregating, but we can explain why neurons have a super high (mM) ATP concentration for two other good reasons:

1. Unlike other cells, neurons conduct electrical signals. Every time a neuron fires it opens channels that allow sodium and potassium to flow through the membrane. Then, it needs to get those ions back across the membrane so the neuron can keep functioning. To do this neurons make prodigious use of Na/K-ATPase pumps, that exchange intracellular Na for extracellular K, against an electrochemical gradient. This is active transport that requires tons of ATP. In a typical animal cell active transport is a relatively small (~1/10th) portion of cellular energy expenditure compared to neurons (~7/10th).

2. ATP is used in actin filament polymerization. Each molecule of filamentous actin is coupled to an ATP molecule, and actin is found in neurons at mM concentrations. Actin is a major structural protein in cells, and plays a particularly important role in neurons. Actin helps create filopodial protrusions; if you compare a neuron to another type of cell you can immediately tell it's a protrusion machine. Even these protrusions (axons and dendrites) have protrusions (neurites and dendritic spines) that are constantly reorganizing to allow for structural plasticity among the brain's neural network connections. One of my dissertation projects was to simulate actin activity in neurons; for anyone's interested, here are some pretty neat visuals of this...

Actin polymerization to create a dendritic spine:
https://youtu.be/JH-hGjzhEFQ

Small segment of a dendrite with surface receptor diffusion:
https://www.youtube.com/embed/6ZNnBGgea0Y

Creating dendritic meshes in python:
https://youtu.be/tDKUU0SqbSA
AFAIK AMD has not announced any Tensor Processing Unit or specific tensor acceleration capability. nVidia Volta [0] does have a Tensor Processing core optimization.

https://www.nvidia.com/en-us/data-center/volta-gpu-architect...
Could This Be the Next Game of Thrones? (The Witcher)
Have you given a thought to Nim? I've never used it in the embedded space, but it should work there nicely. It has Pythonic syntax, but it transpiles to C, so it should fit both your criteria. I'm not sure how the GC fits in, but i think you can turn it off if it becomes problematic. I'd love to see the comparison. Rust is powerful, but I'm guessing a good bit more complicated as well.
Not sure why you were down-voted. Isaac Arthur's perspective is that a species with the opportunity to expand would turn ever star into a Dyson swarm which, in turn, would darken the stars. If ET existed, the night sky would be dark.
Passenger train is just generally severely crippled in the US.

From Louisville, KY you get to factor in the greyhound bus to Chicago, as the nearest passenger train station, because the passenger trains haven't run to Louisville in more than a decade. So far as I can tell, that's the most direct route via train: northwest by bus to go southeast by train, eventually.

You could do it somewhat more directly using a sequence of bus transfers instead, but that's also entirely inconvenient in its own way.
It is not that bad. Either you've your training data local (unlikely) or it is already available in the "cloud" (i.e. a public-facing service). Let's say a typical training set (raw data) is 100G.

Assuming 2.5MB/s Upload capacity with local data, you've uploaded it to your deep learning machine in half a day (100000 / 2.5 / 3600 ~ 11 hours) - which is not that much, as most of your time will be used for development and fine-tuning of your deep learning tool chain anyway. In most cases the data is accessible via a public-facing service, and assuming 1GBit/s bandwidth you've downloaded 100G in 13 minutes (100000 / 125 / 60 ~ 13 minutes).
" Good, safe, dependable trucking companies are in demand."

You could also phrase it this way. Maybe drivers wouldn't jump if they got treated better,
Not denial, but still makes 2 claims (the first one is completely false) that deniers always make.
Why not both?

You can measure a country's success not by how much its top-earners pull down but by how much those at the bottom make.

> It should be much cheaper to have a decent life today than in the 60s.

It would be if not for the problem of housing and transportation being vastly more expensive than they were in the 1960s. You could get a cheap suburban home back then for less than a year's salary. Try that now and you're living 300 miles from the nearest city.
It doesn't necessarily have to lower the standard of living for everyone. Goods and services can get cheaper alongside purchasing power leading to the standard of living being approximately the same. It's not a problem for labor to be cheaper if the cost of living also becomes cheaper. It only lowers the standard of living if the ratio of income to cost of living drops.

Those at the bottom today have a standard of living that is in many ways better than the standard of living of a billionaire a century ago. Why? Productivity gains.
I'm curious of the other services you tried that preexisted facebook, and how they hindered you from connecting emotionaly ?

I think facebook has unique features, in particular a true global scale, but for the emotional side, is there anhthing inherent to facebook that makes connection deeper ?

To be honest, I still feel that the 'real identity' concept is a big hurdle to participate freely, and stops me from posting some of the more personal stuff that I was posting before under nickname based anonimity (even if my contact are all offline relations). A lot of people don't seem to get along with the idea of having multiple profiles targeted to different circles, and switching profiles is actually a PITA in facebook when using it mainly on mobile.

I switched to instagram for a while, but it is yet another niche that doesn't really overlap with what other social services where filing.
Not sure, because the destinations countries for the planes departing from there have some interest (a bit like the US forcing some theater on Europe), and there is some international help for military and security theater gear.
Well. I guess, I should jump into the discussion. I'm a truck driver with 18 years of experience. Between driving jobs I have had 3 breaks when I was doing programming/software development. I had never liked programming jobs, i always enjoyed driving. Programming is something I can do based on my unfinished education.

I'm an immigrant. I follow the industry news. Both industries, I guess.

First. You wont believe how diverse the truck driving jobs are and how diverse truck drivers as a group.
There is a fair populations of drivers with bachelor/masters degrees and pretty high IQs

I had chosen the job because it is always there. No need for looking for one. After initial 2-3 years of entry level jobs (big/ corporate type companies driving dry vans with 90-100% turnover) good drivers migrate to niche
Jobs. Owner/operators with secured contracts. Or specialized freight. Oversized/high security/more dangerous/requiring specific skills (chemical tankers, medical equipment, military contracts etc)

Company drivers in such fields are getting fair pay, very much equal to low/entry level unambiguous programming jobs in $70000-$100000 range. I get paid both by miles(normally under 10%less than actual miles) and time I spend at customers. But, unlike in programming field, I can dictate my conditions. Which is normally would be work hard 8-10 months/year and play with hobbies rest of the time.

But yes, it feels like we are getting squeezed harder and harder.

The problem is very much same like everywhere in the country. Big/corporate type companies with low pay are getting bigger and bigger share of the market. Going into owner/operator business(equal to being contractor/consultant) means get plummeted with regulations and costs of health insurance.
And, starting in December 2017, every truck must be equipped with eLog. Which is watching your every step and hackable by any kid with imagination. Hackability is written in the law. It requires eLog providing interface to truck's engine computer and having cellular contact with the outside world. Just look up eLog and trucking in google and cry and be nervous every time you see 18 wheeler.
Not any immediate plans. Decent amount of development is necessary there. There are so many places in our various systems that work with IP addresses, and many of them don't support v6 addresses.
At the beginning of the article, there is a set of a 2 rows x 3 column set of images by Jason Schulman. The last imahlge on the first row, looks kind of like a blurry Albert Einstein.
How did he pass the multiple choice driver's test? You must be able to read at least some language in NC to pass it(I think it also in Spanish and something else). I took it recently so something might have changed since you were teaching.
It's a carefully managed strategy to ... make their customers happy?

If a company acts in a great way (e.g. replacing slightly dodgy equipment) whenever a customer lets them know they have an issue that's great for the customer, regardless of whatever internal reasoning the company may have for acting in that way.
Amusingly, these exact three things were free in the USSR. I benefited from that a lot. Though most other consumer goods were less affordable and lower quality in the USSR than in the US, and the economy was in worse shape overall. I wonder if there's a way to combine the two systems without people screaming blue murder.
Alan Kay majored in molecular biology and mathematics ... so he probably does understand just how evolution works. (Hint: the Internet is a good source of bios to look at before making assumptions). We put in a fair amount of work many years ago on personal computing and the Internet so that people can be a few typed characters and clicks away from much of the knowledge of the human race ... what does it take to get people to make use of this?
> You don't need to publish [in New York State] unless you want your LLC to sue or defend itself in a suit

"The Limited Liability Company Law and Partnership Law include provisions regarding the publication required upon the formation or authorization of domestic and foreign limited liability companies, limited partnerships and limited liability partnerships (hereinafter referred to as 'limited liability entities'). The applicable statutory provisions should be consulted prior to publishing.

...

Limited liability entities that are formed or authorized to do business in New York after June 1, 2006, which fail to comply with the publication requirements within 120 days after their formation or qualification will have their authority to carry on, conduct or transact any business suspended. [1]"

TL; DR Do not violate the publication requirement. When suing a New York LLC, a common tactic is to show this requirement was not met. That then retroactively dissolves the LLC and lets you pierce through to the owner's assets.

[1] https://www.dos.ny.gov/corps/llcfaq.asp#pubreq

Disclaimer: I am not a lawyer. Do not take legal advice from my Internet comments.
The customer service on Anker products is why I keep buying Anker products. These are smart people who realise that spending money on creating trust pays off. They also happen to make solid products.
> You don't want a pedo in day care,

Makes sense.

> a bank robber in banking,

True.

> or a wife beater as a carpenter.

LOLWHUT?
Joel on Software – Can Your Programming Language Do This? (2006)
I think that yours is a typical viewpoint on this topic among white men. I don't mean this as an insult in any way; since that's most likely your entire life experience. But when you constantly have your competence questioned when people don't do the same to coworkers, you feel unfairly boxed in. It'd be great to solve the big problems of the world; but most women / people of color have to fight to prove that they belong in the conversation. It's a daily frustration, so we complain on blogs about it.

The shitty thing about it is that you really don't know when it figures in. All you see is your white male coworkers advancing in their careers while you're left to wonder "Was he promoted because he goes fishing with the boss? Or is he doing something I'm not?" Never mind that the boss doesn't invite you fishing because you're female and his wife won't allow it.

It's that constant, nagging "What if?" that bothers us. It's not that I don't care about the problems of other people in the world; it's that I'm constantly reminded how little little power I have within my immediate sphere of influence that I don't feel I have anything to contribute outside of it. There is a small but influential political base in this country that actually believes women are second-class citizens (watch how many people the Daily Show was able to get to un-ironically admit that they thought Trump was a better option than Clinton because he was a man -- even other women).

But at the same time, this has caused a backlash against "political correctness" that we first world feminists have to defend against that have very real consequences (abortion rights, family leave, etc). So yeah, the narcissistic essays are gone, but there are still problems to address -- both at home and elsewhere (ignoring the entirely patronizing idea that the world outside western democracies need our help...)
A few exceptions aside, most males just aren't that interesting to look at.

There exist measuring rulers that are less straight than I am, but I have seen plenty of men who I find "interesting" to look at.

When you get down to it, the physical appearance of women isn't all that interesting: a butt that's maybe wider than mine, a couple of bags of fat where their pecs ought to be, and for the most part you can't even see their genitals. Move along, nothing to see here.
This article claims our phones don't last any longer because of some fundamental science with Li-ion batteries. But that's horse crap. The 24KWh battery pack in my Leaf is Li-ion. My laptop has a bigger battery than my phone, also Li-ion.

The real reason our phones don't get much more battery life than 5 years ago is packaging; every step forward on efficiency or battery capacity is consumed by making the phones thinner. Because the manufacturers have decided lasting one day is fine. They don't recognize any consumer demand for longer lasting phones as significant.
its interesting the push/pull that goes on with PED.

many students are taking adderall to ace exams/boards/bar/standardized tests, and athletes are taking steroids/HGH/etc. Its largely considered academic fraud / cheating, but also largely unpoliced.

sometimes i feel the world is becoming like the movie/series limitless. those that you see are succeeding / influential are juiced up.
Retraining for what? Another comment mentioned FDR and infrastructure projects, but this isn't the 1930's. Even if there were a massive infrastructure project, that's good for at most 5-10 years of employment, and then what?

Retraining we can do. However, we can't create massive new job sectors to hire those retrained workers, unless it's make-work government jobs (in which case we'd be better off paying those people a basic income and not removing value from government services by making them more complex and bureaucratic than they need to be).
"As a matter of fact, you can't express any serious idea in 140 characters."

Everything is made of atoms.

The sun is an ordinary star.

Infections are caused by germs.
> I don't think this is necessarily about socialism. It may just be about capitalism, with rules.

Socialism is when the state controls production and _capital_. Setting rules on labor is, in effect, a control on human capital.

I hate the way socialism and capitalism are pitted as a binary choice. That binary choice is a false dichotomy. In reality, they are only binary if every single action of every single person in an entire economy follows the rules (and assuming those rules are perfectly designed to support the official system).

China's foray into capitalism was a group of farmers who quietly made a contract to distribute earnings from their harvest proportionally by yield (which was illegal at the time) -- this was covered by Planet Money, an NPR show. Even deep in the midst of the most socialist time in China's history, they had a streak of capitalism which was later encouraged by the local government.
My opinion towards JavaScript is much like Cato's towards Carthage: it must be rooted out, eliminated and destroyed entirely. I don't know if I'd go quite so far as to say that the fundamental challenge of mass computing is the final destruction of JavaScript — but I want to say it, even though it's false.

Beautiful.

I actually really enjoy node.js and the ecosystem + community surrounding JavaScript. There's seriously a lot of passion and work going in to it.

JavaScript itself though? Horrible. I hate it.
One conclusion could be that inescapable despair is an indicator of globalized psyops. Depressed individuals will rationalize overspending.
Is it more common? Probably. But you know what's also more common? Companies asking for such work and then turning around and saying "sorry, we don't have time to even look at your work."

Fuck these companies that ask for shit like that. Since we can't even hold them to the most basic standards of decency, fuck them and fuck their interview process. Seriously, there's no nice way to put this. Either pay for such work or fuck off. So in other words, pay or only fools will apply. (Yes, I have been a fool myself in the past.)
This take comparison charts to a whole new level. I wonder if this was meant for iOS users to try and persuade their friends to switch.

I don't see it being so persuasive standalone.
> Isn't all that exactly why taxicab meters have a hail fee and then measure both time and distance?

The meters only charge for time when the cab isn't moving, or is moving slowly... This enabled a passenger to run in to a convenience store, and it would be worthwhile for the driver to wait for the passenger to buy their beer (or whatever). Sometimes my passengers would ask me to stop the meter so it wouldn't run up on them ("sure"), others expected it and were fine with the arrangement.

It looks like the gorilla rideshare company slashed their per-minute rate in Phoenix since I last checked - used to be $0.25/min, now is $0.09/min. This makes it not worthwhile for the "ride share" driver to wait for their passenger to run into a store... In theory, since the "rides" show up instantaneously it's more efficient to get a new ride rather than make stops.

Since the "ridesharing" apps charge for both time & distance, the posted price-per-mile makes it seem like you're getting a better deal than you are. 3-4 minutes/mile adds $0.27-$0.36 to the cost for every mile of travel, at $0.09/min.
You seem to be conflating "stakeholder" with "shareholder".
Js is clearly very popular. What are these fundamental flaws that js has that this comment mentions? I don't understand why it would be the "paragon of wasted opportunity".
Show HN: Unsupervised Coin Sorting with Arduino LED Lighting Augmentation
Since the end of the great recession the US has been creating about 200k new jobs per month. BLS says there are about 2 million truckers in the US. That's 10 months of job growth. That's a lot but it's not as big of a deal as some people seem to think. Especially since automation will take over slowly over the course of quite some time.
why would you love someone who uses facebook?

you're all idiots.
On chef and cucumber: https://news.ycombinator.com/item?id=13209760

On Knuth, C, and Haskell: https://news.ycombinator.com/item?id=12741430

On npm and In Praise of Idleness: https://news.ycombinator.com/item?id=12209300

On revenue: https://news.ycombinator.com/item?id=11307264

On cranks: https://news.ycombinator.com/item?id=10931403

On "Great Men": https://news.ycombinator.com/item?id=10166372

On the vastness of space: https://news.ycombinator.com/item?id=9937353

Advice from a doctor: https://www.are.na/block/324266

A+ dig at pg: https://news.ycombinator.com/item?id=7140065

A+ troll: https://news.ycombinator.com/item?id=7229519
> You can measure a country's success not by how much its top-earners pull down but by how much those at the bottom make.

Wealth isn't measured in how much you make. It's measured in choices.

You can measure a country's success by how many choices those at the bottom have.

https://mises.org/blog/wealth-isnt-just-measured-money-%E2%8...

> It would be if not for the problem of housing and transportation being vastly more expensive than they were in the 1960s. You could get a cheap suburban home back then for less than a year's salary. Try that now and you're living 300 miles from the nearest city.

You've now correctly identified the problem. Housing costs in the US are out of control and have been for a long time because we have policies that promote housing as an investment asset that should always grow in value. Many baby boomers have their entire net worth tied up in housing and have supported policies for decades that increase the value of that asset to support their retirement. Housing has become a vehicle for an inter-generational transfer of wealth from the young to the old.
Be very careful about stating that GC'ed languages beat C - jblow might appear suddenly to correct you... with pure common sense.
So the WSJ seeks to bring the 4th estate under control of the other 3?

Below pathetic. Law and (dis)order above all.
I'm a student trying to learn server side programming, I've started with node js. There seems to be a whole lot of modules to help with anything and with ES6 js doesn't seem so bad, and very fast (to write) as well compared to C++ that I've attempted. What are these better languages, what should one learn now for server-side when starting out?
The minimum wage is an effort to increase the welfare of those whose skills are in excess supply.

Economics is complicated and far from reliable. The idea that removing the minimum wage would result in full employment is ridiculous. It would make businesses richer and subject millions of people to worse poverty. There is open debate that the minimum wage even reduces employment [1].

[1] - https://en.wikipedia.org/wiki/Minimum_wage
That's exactly what I do. I only use messenger.com and the fb messenger app. My friends warn me when there's something of interest on one of our college groups, but apart from that I don't go to the main site at all.
I don't currently, but I have been considering it for personal projects as a trial balloon.

At work it sometimes feels tough enough to make sure everyone is comfortable enough with git to push to the step of hoping for signed commits.

Though, as I think of it, as the guy most likely to create version tags, it might be good enough that I adopt the practice, at least for those. Then again, I've not seen a strong need on the projects at work.