skysight-inc/HackerNews huggingface dataset:
Alex, why do you say these hurtful things? You know perfectly well that they use principal components to successfully control away population structure, that the genetic correlations between cohorts are high, the hits replicate across populations, the enrichment sets and tissue expression are predominantly in the nervous system as expected, the polygenic scores are predictive of success even looking at just kids in poor families, and the within-family polygenic scores perform fine. No, it's not some measurement error on the several different SNP chips they used in the ~12 different cohorts or the entirely separate GWASes whose results they replicated, and it's definitely not 'residual population structure'. It was silly 4 years ago to write off GWAS results with that sort of logic, and it has only gotten sillier.
I think that only applies to cells with exposed contacts. You could say that "Power banks" aren't technically batteries - they're phone chargers that have built-in batteries, so they're more akin to a phone or tablet with a built-in battery from a safety point of view, with all the same physical and electrical protections against short-circuits.
Am I the only one who thinks this sounds delicious?
>If genetics can be conclusively shown to determine intelligence how long before someone tries to build a 'master race'?

>That's what makes me uncomfortable.

"It's undeniably true, but it makes me feel uncomfortable, so let's ban it and lock it away so it can never make me uncomfortable again"
Ah, somebody's tamed the article considerably since I last read it, a couple years ago. The article for linkage disequilibrium has some of the math I remember being in the GWAS article. https://en.wikipedia.org/wiki/Linkage_disequilibrium
Manchester Arena: 19 dead after explosion at Ariana Grande concert
Wind tunnels. The workshop attached to DSTO's wind tunnel used to be a model maker's (and foreign order) paradise. I'd imagine that wind tunnels are gradually being supplanted by simulation, but that there is still a demand for the physical test and the associated modeling.

I think the biggest thing we've lost in the transition from physical modeling to simulation is the widespread ability to manipulate materials. The process of model making has an inherent value, whose payoff is the ability to imagine what is possible in the physical world and to make it happen.
I am a product manager at a large Enterprise software company and as such deal with salespeople daily. No amount of money will convince me to take on that job. Some salespeople make a lot of money, but most salespeople fail to meet their numbers and are scraping by in their average salaries, as most of their pay comes from commissions. You also are at the risk of layoffs constantly. Don't meet your numbers, laid off, slight downturn in business, underperforming sales staff let go. Not to mention the amount of client schmoozing you have to do and be ok with being treated like a door mat at every client location. Plus the soul crushing travel. I have tremendous respect for the sales folks who have made it. It is a difficult job with high rewards, but also high risks.
That and the 1500 EUR price. Can you imagine spending 2-3 large, high quality TVs worth of money and leaving it on the counter?

Don't know how practical it is but a cool extension would be to mount it on a movable mount on the ceiling and have it pop up on any surface you like.
How useful are these certifications anyway? I am an Electrical Engineer and have a deep interest and passion for computing. I work on various domains (desktop apps, web apps, etc)

I am planning to shift to a career in application development. Will such a certification allow me to get a leg in the industry?
Theranos settles investor lawsuits
The effect is usually compounding because of how evolution by natural selection works. For example, if gene A gives a tiny 0.1% boost and gene B gives a tiny 0.1% boost, the combined effect is a 0.2001% boost (slightly greater than the sum).
As i said, given an ideal environment, intelligence is purely genetic. This whole focus on environment is important, because we ought to have it right for our kids, but its like saying that a cars performance is about oil brands and road conditions. No, a better engine makes a better car and developing the engines is exciting and important because we know how to make good oil and roads and once the roads are paved and refineries operating, most of the progress will be understanding the engine. Yes you need roads but being able to understand and possibly select and manipulate genetics associated with intelligence will produce huge, groundbreaking changes that will make the world much, much better.
One security isn't really the right point of comparison though. Someone with a ton of money to park in "the market" obviously has the choice of doing so in a diverse portfolio from which they can sell in enormously high volume.

Bitcoin is just one thing.
"If you're reading it, it's for you."
Because nobody else has asked, when you say "cold, hard cash", do you mean that literally? As in a case full of physical greenback?
I am working on [dcompute](https://github.com/libmir/dcompute) which I hope will bring an equivalent experience when running on OpenCL and CUDA, and being written in D will provide all the advantages it does to writing kernels as it does with writing host code (with of course the ability to share compile time information across host and device). I believe that this levelling of the playing field will let the best hardware win.

If you have any question, please ask!
It's just a matter of educating people. That case was only dated to 2005. Most people probably don't know the implication. Once the simple test of system+method detection is applied, a large swap of BS patents can be thrown out at the first sight.
Is there any open or distributed emerging alternative to Facebook yet?
Diaspora seems to have fallen of the radar a while back, wondering if anything else is gaining momentum these days either as a direct competitor or a niche alternative
Why is this not everywhere? I find this way cooler than over-hyped VR.
Do you have any examples of phones with battery life like that?
I'm probably banned for providing a viewpoint that YCombinator wants to censor.

The reason why you guys get varying customer service is basically COST and affect.
Craft a new post with a non-disposable account and title your post "Ask HN: What's the best way for a ~40 year old to retrain and get a job in tech" or "Who's hiring ~40 year old developers?".
Related work:
The artist Jason Salavon is well-known for making work using a software-driven frame averaging technique. https://en.wikipedia.org/wiki/Jason_Salavon

Using analog techniques there is a famous set of photographs of films playing in movie theaters by Japanese artist Hiroshi Sugimoto. In this work a long duration time-lapse photo of the film renders the screen glowing white with a pale outline of the theatre around it. https://www.sugimotohiroshi.com/new-page-7
The Future of Go Summit, Match One: Ke Jie and AlphaGo
And notably the fraction of VOO shares traded on any given day to the total market cap of the fund is about 100:1. With bitcoin it's more like 10k:1. Thus the liquidity worries.
Anyone know if the SNP list is publicly available? I'd love check my numbers against my raw 23andMe data to see if I'm smart :)
In the us and many places, you have to take tests to have a good life. Only smart or priviledged people pass them. Whats the difference between a master class and a master race
Natural selection to increase intelligence on a group level is impossible unless there's variance in the group for natural selection to operate on.

https://en.wikipedia.org/wiki/Fisher%27s_fundamental_theorem...

"The rate of increase in fitness of any organism at any time is equal to its genetic variance in fitness at that time."
After Murray stirred up such a fuss with his publication of The Bell Curve, the APA (the main organization of psychologists in the US) put together a task force to determine what mainstream, scientific, orthodox thoughts were about intelligence. The report is called "Intelligence: Knowns and Unknowns" and is probably your best bet for answering your question. The Wikipedia page on it highlights its findings. It's 20 years old at this point but I don't think too much has changed since then.

https://en.m.wikipedia.org/wiki/Intelligence:_Knowns_and_Unk...
Why a rocky archipelago south of Newfoundland is officially part of France
Stop. Read http://www.erights.org/talks/promises/paper/tgc05.pdf. Then start again.
It's hard to say. If you want a full time employee position, I don't think they're particularly useful. If you're looking to get into consulting or similar, suddenly they look a little more appealing. At the end of the day, nothing beats experience - though you probably get at least some of that through the certification.
I got too caught up in the wording of your first post. I agree completely.
I'll add my anecdote to this. Almost every male on both sides of my extended family taught themselves electronics/programming/science, graduated high school in their mid-teens, in many cases skipped university entirely, and went on to engineering careers at places like AMD, Microsoft, SpaceX, and GE. Even ones who never met each other have this same life story.
Can blockchain help save the environment?
> Requires python3

o_O twitch
Why not just use Tahoe-LAFS? Then you don't have to trust the server to get the security guarantee!
Let's be accurate about that quote, though - that Vox article itself says that a lot of what goes into IQ is heritable, and comes through DNA.

"No genes for IQ" is better interpreted as a statement that it's not just a small handful of genes that determine IQ (or any behavioral trait), but very, very many (plus nurture, but that goes without saying). It cites http://europepmc.org/articles/pmc4635473, which mentions:

The SNP rs9320913 is estimated to account for only 0.02% of the overall variability in educational attainment, but biometrical studies show that the total percentage of variability owed to genetic differences is three orders of magnitude larger (Heath et al., 1985; Rietveld et al., 2013). Since the SNPs with the largest effects are the easiest to find, these results suggest that educational attainment is a phenotype affected by thousands of undiscovered genetic variants, each responsible for a minuscule fraction of individual differences.

...which is not to say that Murray's claims that intelligence and race correlate strongly have merit, since as the article you posted points out, his argument has some severe deficiencies.

Specifically (and this is coming from me, not the article), when a measured trait (say IQ) is a function of a large number of genes, then unless that trait has highly variable selective importance depending on habitat, we would not expect it to diverge significantly between races. Traits that do diverge significantly tend to be either subject to different selection pressures between environments, or involve a small number of genes (with a small number of genes, it's easy for random noise to freeze unusual variants into segregated populations, but as the count goes up the law of large numbers kicks in and we see similar bell curves in all populations). This is almost trivial to prove.
This is pretty typical for most not-amazon (or amazon-competitor) stores, I've found. It's why I am so reluctant to use third party sites, even though I know it's for the better if I do.

Newegg I've found to fulfill the Shoprunner "two day" shipping promise pretty reliably. I actually get a lot of stuff the next day due to being relatively close to their Indiana drop-ship partner/warehouse/whatever.
Great point about the owner/captain regulation. It seems incredible that the little guys won in this one.

Also, chrisbennet's comment reminded me of another piece of the sustainable fishing regulations, which is that the traps are regulated to be inefficient and let the lobsters walk out. As an engineer that is just about more than my mind can handle.
As far as I understand it, it's taboo because the results will be misused, and any results that do exist will not necessarily apply to the genetics 100 years from now but the consequences of their misuse would. And unless we're going to go full Gattaca, then I'm not sure what good the results would be.
This sounds beyond absurd to me.
Do they also block usb ports to prevent you from copying everything on a usb drive or external harddrive, or phone?
Do they lock/solder you machines shut to prevent you from taking out a hard drive / plugging in a new one and then taking it out?
Do they prevent you from .. printing the code? In what parallel world do they exist that they think this would make a difference
> What’s retirement? Sounds boring. I’m single, I have no money saved up, I’ve lived paycheck to paycheck. My fault. I didn’t think about retirement growing up. This is the first time I’ve ever made decent money in my life.

> I bought me a brand-new car, a 2017 Chevrolet, two days after I hit this town.

I don't know what the answer is, but there must be a better way of educating people about their finances.
SoftBank's $100B Tech Fund Rankles VCs as Valuations Soar
The electricity will likely cost a significant chunk of that, if one were running that full time in Germany.

0.5 * 24 * 30 * (30 c/kWH) = $108

However, it'd be a third of that in the states (may be cheaper in WA).
The summary statistics are in fact available on the CTG website, but I'm not sure why you would want to bother. The performance of the polygenic score is about the same as the SSGAC polygenic score for Okbay/Selzam et al 2016, so Sniekers et al 2017 isn't all that helpful in that regard. (And in any case SSGAC is expected to come out with a paper this year with n=1m (!) http://programme.exordo.com/bga17/delegates/presentation/214... which is expected to at least double the polygenic score performance, so it'll be obsolete soon. And I hear there may be a second group with as large a sample size...)
Apparently no one is supporting anything
Life in general doesn't seem to be grinding towards maximum entropy... it appears to be slowing it down as much as possible.

Humans on the other hand...
Held as ETFs? Assuming it's in big ones like VOO, they can see $400M turnover in a business day, so if you're not picky about getting the best fill price and just sell at the bid, you should be able to do it within a minute or two. You can then call your broker for a wire transfer and have it in your bank account within the same day.
I'm a college dropout with only a few years experience, and I'm looking for opportunities to learn - this looks pretty valuable, as well as nice resume material. Do y'all agree?
Apparently, you know very little about the job and how much brain function (mind you, I didn't say education) it requires. And how difficult it is.(just search London taxi drivers study in your favorite search engine) And, at its base lavel how underpaid it is.
Last time I checked, 9/10 of Arkansas working population was involved in trucking or logistic industry. As a side note. Automizing this job will bring total and enormous poverty to US
I believe the contrast adjustment was likely to get rid of any unwanted shades of grey before colouring the two extremes.
The article stated pretty clearly that its concerns were social/political, not scientific.

It called Murray's conclusions "dangerous". What place does an accusation like that have in the assessment of his scientific findings? You can't have a credible scientific discussion about a subject like the racial correlations of intelligence without a high degree of detachment and willingness to go wherever the data leads.

On top of that, the article was disingenuous. I listened to the podcast a couple of weeks ago and I recall a very interesting statement by Murray to the effect that "the IQ differences between members of each specific race are greater than the IQ differences between the different different races." And yet the Vox article implied that Murray was making sweeping and damning generalizations about the races.
The nice thing about Rclone is that it already supports Google Cloud Drive (and a host of other providers) so the technology isn't the problem.

I'm lamenting Amazon Cloud Drive in particular because it was the best deal. $60 a year for unlimited storage and with no caveats (or so it seemed before last week).
Dude lasted less than a year at Google, and the only thing he produced was a huge google doc containing a diatribe on how wrong Google's approach to software development was. Googlers had a good laugh and then carried on as before.
Medical Startup, Looking for feedback
The main takeaway seems to be that master artists can produce amazing things regardless of the medium they use.
Facebook Photo Search
I agree. It seems that Bloomberg "invented" it (there used to be open space offices before, of course, but I don't think they were this style of "all departments and even executives are in the same room without any divisions") and it appears to be content with high turnover.
I can agree with that. :)
A lot of the value comes from getting opportunities through the AWS Partner Network (APN, https://aws.amazon.com/partners/). To advance through the partner level hoops as a company, you need more and more 1099 or W2 employees who have AWS certifications. Therefore, if you get some certifications, you'll be a lot more attractive as a candidate to companies (mainly tech consultancies) that leverage APN to get business.

I hear that the basic ones are very easy, but the professional ones have a bit of heft to them. From a business standpoint, there's no reason for these to be too hard on developers--AWS is trying to push its agenda and needs workers ready with shovels to do so. The benefit could be to identify the most eager partners who can pass a basic competency check to reduce implementation risk, and of course, the training can tour you through the gamut of AWS offerings.
How is it disturbing? Almost every aspect of human individuals is a random variable. What's wrong with intelligence being a random variable too, which could depend on some other aspect of the individual? I think making this a scary fact is what promotes the problems in discourse we see on this topic.
Ask HN: Indie App Devs / Startups in Los Angeles?
I'm in Los Angeles from Australia next week prior to attending WWDC, and was hoping to meet up with any interesting app startups or indie app developers.

Is anybody interesting in meeting up for a coffee, or have any recommendations for startups I can visit?

Thanks!
It's a signal. One of, hopefully, many. Personally, and I speak as someone who interviews many people each year, I tend to care more about projects you developed than your certifications. That said, it all adds up. So I'm not saying don't obtain such certifications. I'm saying, obtain demonstratable experience (e.g., through projects in your spare time) and don't count on certifications alone. The key should be gaining experience and adding several positive signals to your resume. For example, an active github account, open source contributions, cutting edge languages or technologies mentioned on the resume, interesting projects, a blog on the subject of programming, and yes AWS certifications, are all good signals.
There is/was a option available for F1 Visa students called OPT (optional practical training). It could in theory run up ~24 months depending on the company having everify or not.
There's nothing inherent in high population density that makes schools bad or unsafe.
In many places this has already been done; e.g., I work on the 15th floor of a building.
The AWS solutions architects legit and well-respected. Also among the highest paying. Can't really fake your way throug either, plus the test is cheap to take.
That's a fair accusation - you're responsible for increasing the classification of material if you find it to be under-classified, or request a review in the opposite case. So, it wouldn't be surprising if something came across the desk of a decision-maker or the IC's version of middle-management and they selfishly raised its classification hoping it'd be lost in a blackhole for fear of embarrassment, etc.
There are some really neat articles from this link <-- commenting so I can find this later incase I lose it :D
Is it okay to ask if people in certain geography are better athletes than others?
That is awesome, only catch the slow ones.
> There is a single party, and it is The State of Maine.

That's an interesting way of looking at it, but it doesn't strike me as one that contributes much to understanding the phenomenon. Individual licensed lobstermen, not the State of Maine, bear the costs and reap the rewards of their catch. The role of the State of Maine is to set rules about how and how much they catch (to their collective benefit), but the state is not in any meaningful sense catching lobsters.

> I fail to see your reasoning here. A single corporate entity would would prefer to employ the smallest number of people possible.

I'm not sure what reasoning you think you're failing to see. I did not say anything about how many people unitary ownership would employ, nor did I express any opinion about the merits and demerits of unitary ownership as a solution to the tragedy of the commons; I only noted that it is one, to illustrate my point that Kelly's characterization of the problem and its solution in terms of "fairness for the many" versus "maximizing for the few" exhibits no understanding of either the problem or the solution and seems to express nothing beyond her sympathies.
People who live in skyscrapers a few blocks from their offices don't need 101.
Poe's law has applied. Please add "/s" or "no /s" to clarify.
Show HN: Warp – Simple terminal sharing for better developers interactions
I would argue that HR is largely driven by legal obligation.
Why do medical clinics still use CD's and faxes?
Hi,
New to this community. I'm a surgeon, trying to build a solution to a problem that my patients have.
Will see patients who've been referred to me for surgery, will arrive without their xrays, MRIs, labs. We will contact imaging centers and labs, and have to wait for CD's to be mailed and lab data to be faxed! This seems crazy to me in our cloud connected world.
Working on building a cloud based solution to this problem.

Has anyone here had this problem as a patient or with their family? Has it led to a delay in diagnosis or care? Would love to hear any personal stories or just get feedback.
Thanks
AP

instaxray.launchrock.com
Sadly, take-away message from this underdetermined by the numbers you give.

If the cases that come to all of these courts are roughly the same, then these data mean EDTX is only a little more patent friendly.

But if it is true that EDTX is swamped by troll-plaintiffs with weak cases, then the fact that 54% of them steal win, is very damning.
Side note: speaking from experience, you need to be very careful about tying your public identity to any statements about holding this amount of cryptocurrency. I've seen extremely well targeted (successful) spear phishing and identity theft attacks to steal bitcoin from people who posted online about holding much smaller bitcoin fortunes.

I realize your username says `anon...`, but you've already made HN comments about where you live and I only did a 30s glance.
I'm sure you're correct, but be warned that starting a response with 'you do realize' is likely to make you sound like an asshole[0]

0. http://www.urbandictionary.com/define.php?term=you+do+realiz....
Is human intelligence really a thing? Sure, we can all tell the difference between a mathematics savant and a mentally challenged person. But is there really a reason to think that a single number can capture with any degree of accuracy some property of the connection structure of 10^11 brain neurons?