skysight-inc/HackerNews huggingface dataset:
> Any private drug negotiator is going to be in a terrible position because they don't have 100% of the market. They can't walk away,

Having 100% of the market is the definition of a monopsony. That's bad for both patients (in the long run) and pharmaceutical companies (in the short run).

In any case, even an ostensible monopsony pharmaceutical purchaser can't really just "walk away", because so so many of the drugs that they're purchasing are deemed essential. Let's say the government just said, "sorry, you've been taking this critical blood-pressure medication since it was released seven years ago, but now we're not going to pay for it, because we're taking a hard-line stance in our negotiation with Pfizer".

At that point, there are two possibilities:

1) Patients stop taking the drug, and they die

2) Patients pay for the drug out-of-pocket (if they can afford it), and the remaining patients die.

#1 is possible, but a political disaster. #2 is a no longer a monopsony, which defeats the whole premise of "having 100% of the market".
These look cool! Is there a way to get.. more colors? Eg, i'd like to use this for some themes editor themes, but i need a couple backgrounds, foregrounds, etcetc. Maybe 10 colors would do, hard to say.

Thoughts?
or is it because we instinctually have some compulsion to murder?
Well yeah, you'd buy a stamping press and mint 10k/day.

I fear HN underestimates the amount of work people will do to avoid getting a boring (legal) job.
Am I wrong or all the issues seem to be not gender related but about management and they apply to both sexes?
Here are the other articles:

https://blog.ycombinator.com/ask-a-female-engineer-4/

https://blog.ycombinator.com/ask-a-female-engineer-3/

https://blog.ycombinator.com/ask-a-female-engineer-2/

https://blog.ycombinator.com/introducing-ask-a-female-engine...

;-)
What makes you think "the classics" weren't produced in the same way? The Sopranos was originally pitched as a network TV show.
This seems like something that shouldn't upset many Republicans. Remove artificial barriers and open the markets. This could apply to a lot more than just drugs. For example, it would be nice if region restrictions were removed from digital goods.
I think evolution is pretty insightful -- given that these creatures are capable of engineering a space in which humans can survive they clearly have knowledge of evolutionary biology which must intersect our own knowledge. That seems a space with more identifiably shareable concepts than math.
here are a few links:

ingame live map, sadly requires signup (free account will do): https://screeps.com/a/#!/map

shows alliances (player made, not part of the game, js heavy):
http://www.leagueofautomatednations.com/map

another alliance view:
https://pbs.twimg.com/media/Cz1HZrEUcAExwYa.jpg:large
Here's a couple I watch regularly with some great content:

- Computerphile: Interesting stuff about computer hardware and software: https://www.youtube.com/channel/UC9-y-6csu5WGm29I7JiwpnA

- Deep Astronomy: Space stuff: https://www.youtube.com/channel/UCQkLvACGWo8IlY1-WKfPp6g

- Deep sky videos: more space stuff: https://www.youtube.com/channel/UCo-3ThNQmPmQSQL_L6Lx1_w

- Grant Thompson: Expiriments, building things, explosions: https://www.youtube.com/channel/UC1zZE_kJ8rQHgLTVfobLi_g

- Numberphile: math stuff: https://www.youtube.com/channel/UCoxcjq-8xIDTYp3uz647V5A

- Nurdrage: chemistry experiments: https://www.youtube.com/channel/UCIgKGGJkt1MrNmhq3vRibYA

- Retro game mechanics: implementation of retro gaming software and hardware: https://www.youtube.com/channel/UCwRqWnW5ZkVaP_lZF7caZ-g

- Sixty symbols: general physics stuff: https://www.youtube.com/channel/UCvBqzzvUBLCs8Y7Axb-jZew

- Stuff they don't want you to know: conspiracies:https://www.youtube.com/channel/UCrrOic-og4HzhleZqOq4L-A

- Vsauce: Thought experiments, interesting facts, etc: https://www.youtube.com/channel/UC6nSFpj9HTCZ5t-N3Rm3-HA

I don't know if you're into gaming or inane comedy, but I also watch a lot of Funhaus: https://www.youtube.com/channel/UCboMX_UNgaPBsUOIgasn3-Q. dfinitely not for everyone.
I'm just gonna quote something from the article:

> If there is someone who’s making the stuff you enjoy ..., find ways to contribute. If they have alternate payment systems like merchandise or Patreon, consider it so they don’t have to play the “ad revenue works in volume” game.

Do this.

I support a number of creators via Patreon, including Daily Tech News Show and Drunk Kids Gaming.

If you get value out of the content you consume, please consider giving some value back, using a mechanism (like Patreon or PayPal) where you know that most of the returned value is reaching the creator who's content you consume.
I might have to walk that back. It seemed to me that no_std was "more straightforward" and/or "more formalized" than "#pragma interrupt" (etc). But I could be wrong there -- if so, mea culpa (the post is no longer editable).
The Myth of Sisyphus by Albert Camus

Back in college I had that spinning around in my head along with a computer science foundations course (automata, computability, complexity, Turing completeness) and a bunch of AI/AL light reading that was already rather dated. Kitzmiller v. Dover was being covered all over Slashdot and here I was looking at all these examples from the 80s of complex emergent behaviour evolving from simple rules applied to randomness and then simulated over time in computers.

Something clicked in my head and everything made as much sense as it needed to. Life, the Universe, everything. I started to think of the sciences as being just a continuum of studies that describe behaviour at increasingly higher levels of abstraction: math -> physics -> chemistry -> biology -> psychology -> sociology.

Computers made life without specific reason or meaning demonstrable.
Camus made life without specific reason or meaning acceptable.
Mattermark – Top 25 YC W17 Startups
In my case it's to have a single immutable desktop whenever I'm working at home or at a customer site. A 15" laptop screen is enough for me.
It's true, but culture is a much armful as it is helpful as a manual. Most cultures I met while traveling (a lot), including my own, have terrible effects on how we handle sex, success, responsability, feelings and growth.
is there a plan for Ask a Male Engineer series?
The first time a character said "I'll get us an uber" it was pretty realistic for a millennial. But it got annoying the 8th time it happened.
I don't know why Donald Trump does anything. But, I do think he's is of an unknown position in this particular area - so given that we have a problem in the US, and that Trump maybe doesn't have a defined position on the issue, it doesn't hurt to chase the possibility. (On the other hand if I'm just guessing with low-data: the chance does seems low).
Getting anything done in the age of Trump
By that logic, everything everywhere is free if you are willing to accept the consequences. How reasonable the consequences of action are should be somehow part of the definition of freedom.

You are free to say that, just accept that someone can beat you up for it or harass your employer/girlfriend/boyfriend till they fire you or ...
Users should be able to own the platforms they love instead of investors
What price control method would you advocate for?
The US is 8% richer than Denmark, 12% richer than Sweden and 40% richer than Germany on a per capita basis.

https://en.wikipedia.org/wiki/List_of_countries_by_GDP_(nomi...

If you had said Luxembourg, Switzerland & Norway I would have agreed with you. That's only about 14 million people though.
This bot i'm building is less of a "recommendation engine" and more of a "customized web alert engine" where the customization interface is the conversation with the bot. Recommendation engines are a non-trivial problem that companies like Amazon and Netflix spend lots of money on and still don't get right for a lot of people(I have the same issues with both services-- Grace and Frankie Season 3 is not something i'm interested in Netflix, geez). People like us can make google alerts or use Feedly or setup searches for custom hashtags or a million other ways there are to create a personalized information stream. But many non-technical people have to settle for scanning a Facebook feed full of junk, fake news, and ads trying to find the best nuggets of what they actually are tracking. The bot aims to solve that problem and give these people some of their time back.

I'd love to hear any more thoughts on it.
Different people have different opinions on what is considered equal. Getting outraged over perceived slights only fuels the division, and expecting every company across the country to have the same culture is a bit insane in my opinion.

Also, using the term "mansplaining" is pretty sexist. If we're gonna aim for equality, then let's not put sexual undertones in everything we say. It doesn't add to the conversation, just denigrates the main idea by insulting a large part of the readers. Women can be condescending, too.
> TV stars are demanding “movie star” salaries of some $250,000 per episode when they previously were content with half that

One major result of Netflix's rise is that the TV format for entertainment is starting to be seen as on par with or better than the feature film format.

There's something obvious about this from a viewer's standpoint. People are naturally drawn to abundance and regularity. Rather than having 100 discussions about which movie to watch together with my wife over the course of a year, then find that only 20 or so of them are on Netflix, and maybe 5 of them turn out to be stinkers, we can simply pick a show we both know is about a B+, and watch 100 episodes, not ever being disappointed. Also, if I watch the pilot of a great show, then I know I have a whole season to go through, with days of entertainment. If I watch a great movie, then welp, I've just watched a great movie and maybe in a few years there will be a sequel.

From an artistic standpoint, there are freedoms that open up due to having established characters, routine plot conventions, etc. There was an article on HN a while back where Conan O'Brien mentioned that this is why he did exactly the same walk to the stage every single night, or something of that nature.
Biham-Middleton-Levine Traffic Model
I'm not sure the community well understands it at all. The usual rejoinder is something along the lines of "well, I don't see that in the Rust community I'm in."
These tattoos conduct electricity, turning you into a very basic cyborg
That's the thing... Netflix is skilled at producing "good" shows but not necessarily "great" shows.

The third season of Black Mirror is pretty much the only content that I'll rewatch over and and over like I would, say, The Wire.

But if I want to veg out and watch something "pretty good" stuff like Master of None and Love are decent.
"[...] our measure of competence relies on a comparison of the private incomes across people with the same education, occupation, age, and residence in the same geographical region (members of municipal councils in Sweden typically keep their private job).

A competent politician, we argue, is a person who makes more than the median amongst politicians with similar characteristics."
I often wonder this, too; how many hours of entertainment do you expect for $10 a month? My list of shows I want to watch on Netflix is way longer than my hours of show watching I have.
My take is their DVD service was in recognition that they were an overly early mover: streaming content would be the dominant delivery service eventually, intended as their core competency, but they couldn't get there AND assure having a massive customer base without starting the (rather profitable, can't sneeze at that) DVD mailing service to get people on-board and ready to switch to streaming when the technology finally caught up. Methinks that's why they tried to sever the DVD service when streaming finally "arrived" - it's not what they wanted to do originally, it was just a means to an end.

Netflix getting into the moviemaking business is like the Post Office getting into the magazine business.
FWIW, you can disable the "Automatically rearrange Spaces based on most recent use" option in the Mission Control Preferences panel.
Any links to sources of sample apps built with it? Interested to see how you compose pages with Tools.
there are estimates that netflix is consuming about 20% of AWS. AWS does not publish a list of DCs but from regions and AZs you can put a lower bound estimate at 40 so it would be anywhere from 8 DCs to whatever the upper bound is (I guesstimated 20)
Neuro-Programmer 3 – Innovative Brainwave Entrainment Software
My memory is a bit fuzzy, but didn't the physicist start with numbers before Adams' character was involved, and get nowhere?
Isn't that just HN? ;)
Bhagavad Gītā [0]

Miami's airport, Autumn 1983, a shave head Krishna pushes a copy into my hand on the concourse. Says he wants me to have it. Then asks for money. Here's a five. Most people give twenty. Still have the book. Still cheap.

Began my intellectual interest in religion. I've come to think of religion as just another way of explaining the world alongside storytelling and science.

[0] : as it is (abridged edition)
I prefer multiple monitors because they allow a more physical distribution of documents compared to virtual desktops. Having the document I'm going to refer to already in peripheral vision makes it much easier to switch to it than a switch to another virtual desktop and re-orient.

The article notes the problem of having your mail open on the second monitor. There is an easy solution to that: close it. Sure if you then can't find anything useful to put there, you don't need a second monitor.
Poisson-Disc Sampling
Disclaimer: I'm for breaking patents when necessary, although 3D printing drugs is around the corner making it a moot point.

3D drug printing is a pipe dream. The syntheses are way to complex to do at home. You'd be better of just having a CRO make the drug for you.
> This seems like something that shouldn't upset many Republicans.

You'd think so, but they voted against it on Jan 17th (along with nine Democrats).
And the Clinton Foundation's big victory was in getting drug companies to sell anti-HIV drugs in the third world for far lower prices than they would go for in wealthier countries. So I imagine the idea of ending that would be appealing to Trump.
This is so cool, such an interesting and great idea. Really impressive and well-done.
Maybe they should attempt writing it using the Isabelle/HOL transpilers to C from SEL4 project. I don't care if it is C or machine code as long as the proof of correctness is complete, down to at least C library.

Curl is small enough to make it relatively easy and used widely enough to make it worthwhile.
The R&D argument would be much stronger if pharma companies didn't spend more in marketing than R&D in the US.
I wonder whether banks test every £1 coin that passes through their hands.

Either way, being rejected by vending machines is probably neither a sufficient nor necessary condition for being a fake, but it's almost certainly correlated.
There's already the pi-top [0]. I've been considering getting one for work to use without a Raspberry Pi. It connects to the Pi using HDMI and USB so it might work as a portable, battery-powered version of a rack mount console.

[0] https://pi-top.com/product/pi-top
If that were literally all it was about, nobody would have reason to complain. Instead, the concept has expanded out to encompass political views which can be debated in good faith. Supporting certain candidates has resulted in public shaming, if not outright violence.

Do our college students really need to be kept "safe" from mere disagreement?
I don't think this issue is gender-specific, it's a problem for retaining everyone.
This is excellent blogpost, thanks!

Edit: most comprehensive, best illustration, so far I have seen on this topic.
you are cordially invited to join us at irc.buttes.org. Once you enter our chat lobby, an attendant will assist you.
Even Germany’s Post Office Is Building an Electric Car
Specifically content creators with good content… yeah I watch a lot of that.

- Actually Hardcore Overclocking (buildzoid) https://www.youtube.com/channel/UCrwObTfqv8u1KO7Fgk-FXHQ

- Micah Elizabeth Scott (scanlime) https://www.youtube.com/channel/UCaEgw3321ct_PE4PJvdhXEQ — "Art, engineering, reverse engineering, and cats"

- The 8-bit Guy https://www.youtube.com/channel/UC8uT9cgJorJPWu7ITLGo9Ww + https://www.youtube.com/channel/UCcTt3O4_IW5gnA0c58eXshg

- Druaga1 https://www.youtube.com/channel/UC-7I1gU1r6PxBSl87o-7YEQ — "Windows 98 on an SSD", "Installing an SSD in a G4 Cube [Part 2]"… you get the idea

- Kim Justice https://www.youtube.com/channel/UC9ZWVL1Elyt2cdiQYjxS_1w — very interesting in-depth retro gaming videos

- hbomberguy https://www.youtube.com/channel/UClt01z1wHHT7c5lKcU8pxRQ — critical videos about games and social/political stuff too… I recommend "Fallout 3 Is Garbage, And Here's Why" :D

- OzTalksHW https://www.youtube.com/channel/UC6Jxh95N32m1JvKG_-fQ6QQ — hardware reviews and stuff

- Paweł Zadrożniak https://www.youtube.com/channel/UCximsD7EJ38jzCNgfP_YTmA — next level floppy drive music
And I bet you don't need to write a spam bot to spam your resume out to N * 10^50 job postings. It sounds like you've outgrown the need to seeks answers to questions you might have asked earlier in your career. That is a nice position to be in :)

Still, one could argue that flirting w/ the company a bit at the point you make a first impression, possibly in a cover letter, is in your best interests. If someone needs you, they'll offer to pay what they need to. If someone wants you, they'll pay whatever it takes to retain you. Sometimes those numbers are the same. But if a company would be willing to go the extra mile to make you happy, and you give them no reason to feel that way, you're leaving money on the table.
The key challenge is that the government has so grossly distorted the market, on multiple dimensions, that the actual levers within the pharma vertical are opaque to all but the most embedded incumbents. (economists refer to these as hidden externalities).

These market-distortions have all but eliminated the natural cost-competition that one would observe in other sectors, such as commodities or manufacturing. The best thing the government can do is back off completely and make those pharma companies REALLY sharpen their pencils.

For those of you who believe MORE regulation is the way out, that's called "trying to dig your way out of a hole" or "repeating the same nonsense and expecting a different outcome." Please challenge your beliefs.
Nintendo Switch stock shortage issues may extend through 2017, GameStop says
Is polymer really a Web standard? Seems like something Google is pushing down. The implementation is quite fragmented.

I'd love browser makers to focus on the basics like rendering, js and asm.js and leave the rest to libs.
> What prevents a shop from accepting the coins after Oct 15th and then they take it to the bank?

The law, which only allows individuals to exchange the old coins after that date. Yes, shopkeepers could change their bills for old pounds and then deposit them in person to their current accounts at the local branch, but if I'm a shopkeeper then I probably have better things to do with my time.
I wonder if the increase of size of seed round corresponds to startups waiting to seek funding until they are more mature.

The second seed round, makes me even more suspicious of this: are we simply renaming A and B rounds to seed 1 and seed 2 rounds? The increased size of these rounds would seem to imply yes.

Furthermore, I wonder about the lack of stigma in a second seed round. It seems like this would happen a lot if the founders didn't raise as much as they needed, and investors felt they could get favorable terms, perhaps more favorable than the first round of investors - which could mean the exact same terms, but operating on additional months of performance data.

To me, it seems like most of the changes in the State of the Seed Industry are about definitions and semantics.
Not wyldfire, and I think that claim is a mischaracterization, but the main obstacle to using C++ in the kernel is that some of its language features require runtime support (new/delete, globals/statics with constructors, exceptions).

You can of course just ignore those when writing kernel code- they get ignored in application code much of the time! But I suppose at that point it could be argued that you're just writing C with a C++ compiler?
Nfusr: A userspace NFS client for Linux
Can't leave it at one book, because there are four which all tie into a whole:

1. The Book of Five Rings (how to manage yourself)

2. The Art of War (how to manage your campaign)

3. The Prince (how to manage your domain)

4. Proverbs (the wisdom of generations of people in positions of power)
Yes, fair point. That's the kind of content I actually did enjoy a lot.
It's called Ask HN
I think there's a case to be made that, in general, women may be more sensitive to some universal tech industry issues which men tend to shrug off or otherwise deal with differently.
My point was that these are 3-year-old cars, most with light usage. It's easy to find examples with 15k miles. The packs have held up very well - mine had lost at most 5% of its range, if that. So, assume 22kWh capacity left, that should be worth $4k alone by the author's metrics.
That top comment is the one that really invalidated most of the article. Multiple monitors is to give you enough screen real estate for all components of task. It is not to stream twitch and watch Twitter scroll as you try to write in a text editor.

Putting distractions in a separate 'workspace' and making conscious decisions to switch contexts is a good idea, but it isn't related to having a second monitor, IMO.
I've read the plot summary on Wikipedia and am judging its realism based on the quote, yes.
Any private drug negotiator is going to be in a terrible position because they don't have 100% of the market.

That's absolutely not true. Look at the HCV treatments. The average discount for private insurers is 40%+. And that's just one example. They are tons of drug classes that are very heavily discounts to private payers.

Members of a health plan can't just move from one plan to another whenever they want. There is annual enrollment. Members are somewhat captive.
> I’ve been writing web applications for over a decade and it’s utterly shocking how little JavaScript I know!

I'm glad he admits this, but then what exactly makes him qualified to opine on the language?

Look, Javascript is not great, and I'm perfectly open to the thesis that Node.js in particular is a Bad Thing -- I'm C# junkie, for crying out loud -- but supporting that thesis with a series of assertions from someone with little relevant knowledge is not terribly convincing.
I had the exact same reaction. Common themes were along the lines of not having confidence in your direct manager, especially in cases where technical folks have been promoted into management positions. I hear this all the time.
Samsung to sell refurbished Galaxy Note7
Is there any reason to think that Trump doesn't have investments in airlines that are competing with the ones hurt by this ban?
Are You Sure You Want That DMCA Takedown to Be Permanent?
Optane Memory – A bridge between DRAM and storage
I believe you'll find that here in the comments section.
Could this be used for learning AWS instead of starting the clock on the free year of AWS?
That failed because people don't like to carry coins, they prefer bills.

In the UK they don't have a 1 pound bill, forcing people to only use coins.

Coins are cheaper for the government since they last much longer.

So if you were a government, which would you pick: What your people want, or what's cheaper for you?
If that is true, then the person who conducted this study must have a below average income.
Canada Pot Stocks Surge After Report of Legalization Date