skysight-inc/HackerNews huggingface dataset:
That may be. I've not worried about it though because they do notify you and let you know there's been a request for a refund.
A couple of years ago I was researching emerging Rosacea treatments and if I recall correctly, Potassium Dobesilate was found to clear up psoriasis plaques very effectively.

I'm at work so can't verify that, but might be an interesting read for you. Never give up hope, there's a lot of work being done in this area.
Sam Peltzman in "Regulation of Pharmaceutical Innovation" shows how the 1962 FDA regulations have slowed down progress in pharmaceutical development to more than outweigh the improved safety. I.e. it's a net negative.
This seems clearly dated. For example:

> For example, binary trees are always faster than splay trees for workaday problems.

I assume by this Pike means unbalanced binary trees (if not, then red-black trees are decidedly not simpler than splay trees, especially if you need to delete). In that case, I don't really believe it. Nobody uses unbalanced binary trees anymore for good reason: they have awful performance when you do something as simple as inserting keys in sorted order.
The Republicans could have shown their seriousness about free market healthcare and consumer oriented lately if they had required medical pricing (and quality numbers) to be transparent so patients can make an informed decision.

Of course they didn't but I think this needs to be pointed out repeatedly.
>I've talked to a few U.S. citizens that worked abroad who said healthcare in European countries is universally available but the demand outstrips the supply causing longer wait times to get treated than in the U.S. and that they prefer the U.S. system.

Whether we want to ration care by ability to pay or by another means, such as severity of illness, care will have to be rationed -- and the degree to which it must be rationed is inversely related to what percentage of people are covered by it.

So of course well-off folks will perceive a system with a greater percentage of people covered and with care rationed in a way other than 'ability to pay' as being worse than a capitalist system -- they have to wait longer because they're standing in line alongside folks who, in the healthcare system they are used to, could not afford to be standing in line with them at all.

The question is whether that drawback is worth providing access to care to folks who otherwise would not be able to access it.
Anecdotally, when I lived in an urban condo, half the building was empty-nesters -- couples who raised their kids in the suburbs then moved back to walkable smaller city apartments after the kids left the nest.

The problem demographic is couples with kids. Our urban schools are bad, so they leave the city to find good schools. But people with no kids -- either before children or after they leave for college -- are living in cities.
I'm not sure I follow that logic. Lot value is difficult to assess and frequently wrong from an assessment standpoint.

The cost to tear down a McMansion that isn't depreciated way is very high, making the lots value questionable. Additionally, since tract housing is often identical in most ways, if your neighbors homes are going to shit and depreciating, that will impact the lot value too.
I've never understood what gUI code editors provide over vim/emacs.
I don't understand, this post has no link and no text body, just a recursive link to this discussion page. Where is the "horror story" mentioned in the title?

EDIT: Oh I see, the original post is buried down in the thread, because it has been posted as a comment. Perhaps the mods could fix this?
M_Grey did not say 'many millions' about the Harry Potter bit, that's a strawman that you introduced.
if there's no money to be made with drugs, there may be less research into drugs, and they might mean no drugs at all.
Then why does this not happen in the US? Even in Germany you can call a doctor and get a reasonable estimate upfront. Try doing this in the US.
Yes, there is that.

I keep being surprised that major employers keep paying the SV surtax to employ engineers in the Bay area rather than in cheaper places. I understand these organizations need to keep people in the Bay area, sure. It's the center of the industry; it's where a lot of new things happen. But do they need so many people within a half-hour of HQ?

Seems like an obvious place to cut costs.
if a line of ten cars are stopped at a light at least three people are on their phones.

As a cyclist, I often check who is on their phone when I pull up to a light. My guess would be even higher - 50-75% of drivers are on their phones when stopped at a light.
This strikes me as circular logic. "The reason healthcare is expensive is because the US is expensive."

I have no problem with the idea of healthcare expenditures increasing proportionally to GDP because it's a luxury good. This is logical. I'll pay more to protect my life than widgets.

But I don't see the connection between this and the thesis:

>Now, to be clear, my position is not that we ought to be spending as much as we spend. My position is that the issues we face are very similar to the issues faced in Europe and other prosperous countries (and are generally similar to patterns many decades earlier). They are largely differences in degree, not kind. Our large apparent cost differences mostly originate from our significantly higher material standard of living. The long term increases found in the United States and other developed countries are generally a product of ever increasing material living conditions and varying levels of productivity in different economic sectors (healthcare being labor intensive and relatively high skilled at that). Despite the fact that all developed countries allocate a large and increasing share of their consumption expenditures on health care these these richer countries, including the United States, still spend more on other forms of consumption.

That sounds to me like the cost of our healthcare is ultimately up to the market, but that's not a thesis to fight for, as it's always a fact.

By using end result economic data like GPD or AIC to compare healthcare costs the analysis ignores the changing cost of inputs. Those rising costs should be linked to changes in business conditions.

Healthcare costs have been rising faster than inflation. And they have been rising faster than the material standard of living in the US. There are structural problems.
Or your thoughts are mixed with other peoples because you were defined globally.
It's amazing that most companies, including tech companies, operate technology with a diaspora of people across the globe. Yet the bigshots need to be in SFO for reasons.
Technology replaced 99% of jobs for horses, as mechanical muscles become somewhat equivalent but cheaper than real muscles.

As mechanical minds become somewhat equivalent but cheaper then real minds, there won't be anything most humans can offer where it won't be more efficient to do something roughly similar with machines instead.
We didn’t lose control of the Web – it was stolen
Just a heads-up, you can get 1 CPU and 0.6 gigs of RAM for free with the new entry tier of GCP: https://cloud.google.com/free/

(Disclaimer: Google employee, unrelated product area)
The local software doesn't really carry the same security concern.

With cloud-based or in-person tax preparation, there's a risk that a single breach could compromise many, many tax returns. With offline software you have no such exposure, it's not like it's exposing open ports to the internet.

At least in Canada there's a whole slew of free tax preparation software available, offline desktop and cloud-based. The government even lists the various free and paid options: http://www.cra-arc.gc.ca/esrvc-srvce/tx/ndvdls/netfile-impot...
If trump administration actually manages to simplify tax code and kill the stupidity corporations induce via lobbying such that I can file my own taxes. I would have a lot of respect for him.
"in other words, talking about the value of a drug if you're arguing to lower their cost is the last thing you want to do! "

I have no idea what this means.
Logitech Class Action Lawsuit Over Allegedly Defective Video Home Security
It's not like these things people have done are exactly safe and side-effect free already. People have:

* Made entire species extinct through hunting and deforestation

* As a side effect of industrialization, dumped enough CO2 to change the climate and will probably keep it up

* Domesticated multiple other species into being dependent on us, from crops to farm animals to dogs

* Started work on AI and machines which might even replace us one day

Genetic modification isn't a one-way street to destruction as much as AI is, or industrialization.

Also regarding perpetuating life: the one thing life has in common is that it perpetuates itself. We'd be a shitty species if we perpetuated machines or microbes instead of ourselves.
It's 24 Nvidia DGX-1 servers, which contain 8 GPUs each. It's worth noting that Nvidia already have their own 124-node DGX-1 installation, which would have 992 GPUs.
What other sense is there to take it?
for elective/ non-essential medical needs, private healthcare is good. but for essential care, what price can someone put on their life? it's a means to extort if life saving procedures are private!
Since some people are downvoting for bad reasons, I'll just toss in this anecdote:

My parents were audited by the IRS for 5 years straight. They were convinced that my father "was hiding income through losses in your wife's business." My father was a surgeon; my mom ran an antiques shop. The IRS auditors setup camp in our living room for a month going on five years. That quote was straight from the lead auditor's mouth. I remember it very starkly as a young teenager. (I said hi to them each morning on my way to and from school) It really peeved me that they viewed my mom (the woman) as a failure and only a place for my father (the man) to "hide income."

Every year they came to the same results. My mom's bookkeeping was a mess, but she always overpaid her taxes and we got a refund at the end of the audit. The best kicker? My mom made more than my dad. The IRS thinks women should make less than men (by word and by audit).

As for the historic reasons of this thinking, see my reply below.

If married filing jointly isn't sexist, why are the income brackets different? Even for married filing separately, why are they different than for single people? Sit and think about it for a minute.
In the first paragraph, "Meanwhile, Massachusetts Sen. Elizabeth Warren proposed a bill yesterday to allow free government-prepped returns."
Thanks!

Our primary problem is that GPUs tend to be the epitome of a bad initial market for startups to pursue, since they require large (very large) volumes and very large fixed costs. If you happen to have a better business model to get into the GPU market, drop me a line :)
Show HN: A general-purpose encoder-decoder framework for Tensorflow
If it's anything like most universities I knew (especially in the 90s and early 2000s) then their CS department websites can host all kinds of documents, papers etc such as this, e.g. from ESR stuff to "Worse is better", Beejs guide etc.
Trestle: Create your own writing space
Guess it really depends. Maybe the frontend landscape can be a bit more chaotic since JS started on really shaky grounds and so many new things come out all the time, but I'd say in general programming is still quite rigorous, especially if you're a big organization and can afford all the time and resources to apply all the best software engineering practices with a whole team. Even if not, modern developers generally do quite well. Actually, hasn't the problem people been complaining about centered on the presumed disconnection between CS academia and actual programming, about how a lot of graduates just simply can't code a simple task? I'd say a lot of theoretical CS is just not that easily applicable to actual engineering work. There's a reason why people divide science and engineering. The latter is so much more about ingenuity and practicality in a lot of senses. They're not the same thing and it would be really harsh to classify the whole field as some "medieval architecture" stuff. Not to mention there are still plenty of great works in medieval architecture!
Also, e.g., the Moon landing conspiracy theories involving Hollywood and director Stanley Kubrick.
Most of the issues with Backblaze revolve around having multiple drives / external drives. Also, they give a very incomplete backup (examine the excluded files closely), for example, overall across my drives Backblaze only actually attempts to back up a little over half of my data.
I love that there's just a nuclear warhead hanging out in a field in North Carolina.
It's almost that simple in the US if your situation is that simple. What happens in NZ if you make $400 selling vintage cabbage patch dolls on eBay? What if you earned $1k in returns on your investment account? What if you are renting your place out on Airbnb?

If all you have is a simple income in the US, then the 1040ez is a single page and you can file it for free online if you make under a certain amount. You can pay a few dollars to file online if you make more.

Obamacare has added an extra level of complexity now, but that is also very simple if you don't need or want the subsidy.
OneOps
I have a severe migraine attack, I need narcotic strength pain meds. Only place to get them on short notice is the Emergency room. Takes four hours and I get a bill for $3,000.

This has nothing to do with US being expensive. It's a broken system.
Have you tried a low-carb diet before, out of curiousity?

I ask because what you described as symptoms mirror many of mine (but mine were not nearly as severe). I found that prior to modifying my diet I'd have "random" flare-ups that I could not attribute to anything environmental -- or so I thought.

I started a ketosis diet for weight-related reasons, but quickly found out that the skin issues I'd been experiencing abruptly ceased.

My hypothesis is that I have a specific sensitivity to a modern wheat strain. I'm not sure which one it is yet, but that's going to be my goal over the next year.

My experience is my own, so I don't want to give hope if my situation is different, but the diet change is doable for a short period of time to test a hypothesis.

Shoot me a note if you want to discuss further. My contact info is in my profile.
The risk for liver damage related to Tylenol is mostly related to chronic alcohol use. Safer guidelines in the US have decreased the maximum from 4 g in 24 hours to 3 g. This is still 4 doses every 6 hours.

NSAID use gets iffy in diabetics. Especially if you've had poor blood glucose control, your kidneys may have been damaged over time.

This is a discussion to have with your primary care provider.
>Name one other country that repeatedly threatens to completely annihilate another one and isn't labeled "terrorist".

I'm not sure if "death to America" qualifies, but if so, it's not cool to call Iran "terrorist" at the moment.
I hope someone file my taxes first because my tax return always ends up as owing government tens of thousands of dollars...
the no.1 reason why people seem to want to move to suburbs is children (IMO, anecdotal etc.)

I don't think it's anecdotal.

In nearly every city in the US the urban schools are bad and there are much better suburban schools. It's not just a funding difference as many urban schools do get decent funding. It appears to be a complex issue of parent engagement, varying leadership quality in different urban schools, and peer role models and family life.

Whatever causes suburban schools to be better, I believe the gap is narrowing. Today's high school population reflects parents' housing choices ten years ago. Urban elementary schools are already far better than they were a decade ago.
Points like this sound a lot better when its not you that are lacking access to medical care.

(Presently) Consequent is not the same thing as nessisary.
Or then the gov't can require certificates of non-circumvention of rules so that if they try circumvention games like this they can still be charged hefty fees.
It might sound bad, but usually, when I was doing volume, and I would travel to the different country, region, I would call PayPal central and let them know. While I am all about privacy, this always made them put some comment on my account that helped me pass all the bad things. "We need more documents" issue? Solved in hours. $20K spike of revenue in few days? Not a problem!
(I'm a seed-stage VC, but as a caveat I'm not an expert when it comes to cap tables.)

He's an example of where having many notes can hurt founders:

- Raise $2m at an $8m cap, 15% discount.

- Raise $2m at an $18m cap, 15% discount.

- Raise $2m at a $28m cap, 15% discount.

- Sell 20% of company for $X in the Series A.

Caps are "sort of" like pre-money valuations, so the founder might expect that their dilution from the 3 notes is approximately 2/10 + 2/20 + 2/30 = 36.7%

Here's what actually happens in 4 different scenarios:

1) Raise $10m at a $40m pre. Dilution from the notes is 20.0 + 8.9 + 5.7 = 34.6%

2) Raise $7.5m at a $30m pre. Dilution from the notes is 20.0 + 8.9 + 6.3 = 35.2%

3) Raise $5.0m at a $20m pre. Dilution from the notes is 20.0 + 9.4 + 9.4 = 38.8%

4) Raise $4.0m at a $16m pre. Dilution from the notes is 20.0 + 11.8 + 11.8 = 43.6%

For the founder, #1 and #2 are better than expected, #3 and #4 are worse. It's not hard to get into situation #3 or #4 if you raise money from strategic investors or angels at high caps, and then Series A investors drive your price down below your most recent caps because that's where the market is. The 9% dilution difference between the first and last scenarios is fairly dramatic. When you combine that with the 20% dilution from the Series A, it's the difference between founders and employees having ~45% of the company vs ~36% of the company.

(Source of calculations: https://captable.io/company/8/convertible-notes/calculator)
It's not true in Europe at least. Amsterdam (where weed is legal) has the strongest strains available on the continent. They are supposed to knock the socks off even very experienced users.

Many studies like these only focus on US data and forgets about the rest of the world so they get flawed results. The strongest alcohol you can find is from Northern Europe and Russia, where it never has been illegal. In Islamic countries, where it is illegal, black market alcohol isn't stronger than anywhere else.
Most likely because the US does not have capitalist medicine.
I get that companies want to have an SV presence but you can do that and limit your headcount there. I also get that some people really value the ability to hop jobs to other geographically close employers but options (which is effectively what we're talking about here) have some upper value.

I expect it will all self-correct. There is new housing coming on line. There is some upper limit to the premium companies will pay and some lower limit to the squalor software engineers will tolerate to live in SF. Market corrections can certainly happen.
I'm very liberal but I came to that conclusion based on a lot of economics study. And am liberal only because demand side economics makes much more sense than supply side to me.

You must have talked to a lot of weird Bernie supporters because almost all of the ones I've spoken with were incredibly articulate and rational about their views.

I've actually found conservative voters to be incredibly ignorant with arguments based on on "muh freedoms" or "muh jobs" or "muh terrorism".

Ask them why they like Trump they can't tell you anything reasonable.
I'm curious if others are seeing tear down fest in semi-urban neighborhoods?

So I live in Metrowest Boston Area. I own a multi family. My wife, infant son and I live in modest square footage despite having fairly generous annual incomes (e.g. well above AMT tax rate).

My parents used to live nearby in affluent town (Wellesley) before just recently selling their house to a developer... who of course knocked it down to build a gigantic pimped out house. The same developers was buying 4 other houses at the time. In short Metrowest Massachusetts has become tear down central.

The problem is other than foreign investors (a lot of Newston, Weston, Wellesley, and Needham is getting bought out by foreign investors) nobody from my age group.. the age group that is looking to buy houses wants a super mansion... even if its decked out (That is these houses aren't McMansions. They are real mansions).

From my general experience of talking to other educated thirty somethings is people want authentic and charming not McMansion and yet there all these new houses replacing old New England house.

Yet these new houses are priced ridiculously high. And again talking to other peers it seems gone are the days where people buy 4-6 times their salary. People are buying sometimes as low as just twice their salary and completely fine. And if people want convenient they are going for condo and not McMansion style.

Historically New England has been fairly bubble proof. I fear that time is coming to an end.

When it does happen I might buy some of these big boys and convert them to multi-families ... BTW this is exactly what happened to parts of New England in the late 19th and early 20th century [1] where giant houses were converted to multi families aka Somerville and Waltham (where I live).

[1]: https://en.wikipedia.org/wiki/Triple-decker
Also if you need to do an "extreme" restore beyond what's available in the web app, Backblaze requires you to give them your password in plaintext via email and if you use a private key to additionally either share that in plain text via email or disable it. Of course, I changed to a temporary password but nonetheless this was an extremely concerning experience to me as a security-conscious person. Backblaze is great until you actually have to do a restore. They are a huge company and could use secure channels if they wanted to.
That argument is bunk, because the high density areas are the ones struggling. That is literally an argument for suburbia. State and federal funds do a great job outside of cities.

In my state (New York), US and state designated highways are maintained by the state if it isn't located in an incorporated city. So my city (Albany) can barely afford trucks to plow the snow, but you literally cross the city line and an army of DOT trucks are plowing. Long Island is a great example of this, as "towns" with 300k people aren't incorporated, so they get "free" services.

Even sewers are the same story. It's way more expensive to maintain buried infrastructure in the city and very cheap in the burbs. Fewer connections == fewer excavations == less labor.
while i sympathize with the implication that facebook and google are not socially valuable, it's important to note that those advertising engineers help finance free worldwide communication, self-driving cars, and smartphones.