skysight-inc/HackerNews huggingface dataset:
Sickle-cell anaemia is the ur-example. There will no doubt be others we haven't discovered yet.
Can you quantify this discrimination?
I was being a little flip of course, IQ is generally accepted to be a Gaussian distribution which is symmetrical, the mean and average are at 50 percentile so it is a little bit of a math joke that of course then, 50% of the people in a large enough sample will be below the 50 percentile.
Next time I have a really hot pepper I'll test this theory with the bacon fat I keep in my fridge.
Good vision is less necessary for hunting than you might think. One common hunting role is simply to walk though an area while making a lot of noise. Abstractly large numbers of people have poor vision in large part because our ancestors could get by with poor vision. Traps and fishing are other examples with minimal requirements in terms of vision.

Remember, hunter gathers don't need to read tiny text, or the pattern of bark on a tree. So, even what we think of as poor vision was actually often 'good enough'.
First-year doctors will be allowed to work 24-hour shifts starting in July
I hope this is some kind of very, very dry irony :)
In terms of rent-seeking watch out for Donald Trump's proposal on infrastructure spending. A massive tax break for private building and ownership of toll roads is the epitome of corporate welfare to rent-seekers.
What is this article, I can't. In what world do we live in where we paint a $425m exit in a bad light?

> They built their servers on top of Node and used MongoDB to store data so that the web app would load really fast.

I stopped reading here.
I think the thing with "Buffy..." is that over the 7 seasons it moves from more-or-less a series of self contained episodes to full season length arcs. This was a broader trend in TV as we moved towards box set binging and then on-demand viewing and I think it's key to Buffy's place in the TV canon that not only is it well written gripping and bold TV but it speaks to -- and seems to crystallise -- broader cultural trends in TV consumption.

Other shows had moved in this direction (eg. the Star Trek franchise esp. over the span of DS9) but none I think as fully or as satisfyingly as Buffy did.
> From 1979 to 2013, the FISA courts have denied 12 warrants

That's also true of you change the time period from 2003-2013, since it denied zero from 1979-2012. (It's funny that the low rate of denial over the whole life of the FISC has been cited to support the idea that the court has become a rubber-stamp of the post-9/11 surveillance state, when all of the actual denials are in the post-9/11 period.)
U.S. Jobs, Pay Show Solid Gains in Trump's First Full Month
Ten years ago I thought we were all going to solve this with OpenID and strong protections on the provider side. [1] What happened? I know a bunch of providers moved on to OAuth which let users authorized 3rd parties to do stuff on their behalf. And then at some point we decided v1 was hopelessly broken and moved to v2. But today it's still the rare event where I can login with my {Gmail, Hotmail, Yahoo!} account.

[1] U2F, authorized devices, predictive phishing protections, etc.
Beyond Compare (http://www.scootersoftware.com/)
tres commas :)
I'm not sure I can explain it fully, but my understanding is that it is related to the probability distribution of the abrasive technique.

The technique involves random rotation and random motion, using lapping blocks that are the same size or smaller than the mirror. The center of the mirror is the most likely to be contacted by any motion, so it is abraded more frequently and becomes the deepest point, while the edges are worn less. The distribution between "less" and "more" is spherical.

I can at least understand the process of grinding or lapping a surface flat. Here are a couple examples:

https://www.youtube.com/watch?v=jx1D0buRCOY

https://www.youtube.com/watch?v=REeGn4hN1Bg

https://www.youtube.com/watch?v=ATG_UYYfx7w
I'm guessing whatever they used as an HTTP client did it for them. It's a fairly common way to encode spaces (the alternative being %20 of course - encoding as "+" looks much cleaner).
It's sad the first comments are always stuff like this. So you want millions of people to suffer genetic diseases because income inequality?
Of all the things to modify though, why a transcription factor? Of course there are things in the genome which modifications of would have problematic results. The question is if we should modify those parts we do think would lead to a better outcome, not the ones we know won't.
A Portable Panic Button for Immigrants Swept Up in Raids
What software/hardware are you using ?
seeing as how its a new (and advertised) power feature to windows 8, why would they nerf it?
Ran into one where it demanded I choose from a drop-down list, e.g. "What was your first pet" had "dog", "cat", "hamster", "gerbil", etc. I recall the list having a scrollbar, but there was not even enough choices for eight bits worth of entropy.

Oh, and they referred to these security questions as "2FA."
Maybe the GPG Suite folks should stop writing the integration in such a fragile manner. Maybe they should use the time the upcoming macOS is in developer/public beta to fix any issues ahead of the release? Maybe GPG Suite shouldn't be a thing given the lack of interest and support?
It's an orbit map (showing nadir of the orbiter).
Hi, thanks!

We regularly test different things, but few are as extensive as this "server location test".

This one was quite easy to do - and to revert - even when doing it for a lot of sites: just duplicate your sites on another continent and change your dns-settings.

Sadly we do not blog about this stuff. As our customers are not particularly fond of sharing their data - and blog posts without precise data are not useful at all...

Additionally, most of our assumptions and hypotheses were wrong. So most of our blogsposts would sound like:

"We thought google would work like this, but sadly we were wrong"

SEOs might like these posts - but potential customers probably not so much :D
Aren't chipotles smoked ripe (red) jalapeños? I have to second pasilla chiles as well. Toasting them over a flame and blend them into soup stocks is one of my favorite uses, personally.
The editor is noticeably laggy on my Xubuntu VM. Emacs/vim are speedy, as is VS on the host.
Official solution https://support.twilio.com/hc/en-us/articles/223179908-Setti...
It's funny how many replies you're getting from new yorkers pointing out that seinfeld/friends actually had much larger than average apartments. The fact that all those years later you still think of them as "small" means the cinematic trick worked!

But why did Seinfeld/Friends engage in this trick?

My guess: Seinfeld/Friends was aimed to appeal to a mass american audience, which is why I imagine they had such large apartments -- they wanted something that still looked "small" to middle americans and outer suburban dwellers, but it still obviously had to be much larger than real manhattan apartment sizes, because filming in a realistic 350sqft apartment set (1) would have been awkward to even shoot (2) would have seemed so small as to be hard to believe or at least steal the scene focus when the apartment is supposed to just be a backdrop.
This is like the premier example of a false dichotomy.
Ebooks are fine for quick referrals but I simply can't stand using them for sustained reading. If I'm engrossed in reading a paper book, I'll knock off a hundred pages without noticing the time. I try to do that on my iPad or a computer monitor and I'm edgy and disinterested in just a handful of pages.
We understand the compiler pretty well. You can grab a Bio textbook and find incredibly detailed diagrams of how the genetic transcription process works. It is true that we don't understand every factor, but it's likely the most significant ones are the ones we understand best.
what does, not what's (what is).
They only operate in Europe where computing services are generally cheaper and they seem to be running on processors that are a few years old. It's not outdated old but there's a chance the servers are what remain after a more premium product is upgraded.

Also there are no performance guarantees, no SAN for the SSDs (no redundancy so much lower cost), limited bandwidth and a lower SLA.

I'd guess that since there are no performance guarantees, they're likely overcommitting substantially.
Here's a sample of mine:

Model of first car? zSuI2LR9DvDYwr04 (drop top!)

First city visited? GGSrqPB78tcJ2WB9 (what a trip!)

Street you grew up on? 1pAXzzns5owXNYiU (very quiet!)

Favorite food? oEW5AQ738bkGf6rj (it's delicious!)

High school attended? 3i5OfyNhnWD0bQVy (go Nonces!)
That would certainly make more sense than any kind of public dentistry service, though it's not clear there is a lot of room for improvement there. What makes becoming a dentist hard is, basically, medical school. It's possible there is some low hanging fruit there, but a lot of that hardness is intrinsic.
Only if they were aiming at where we are now, which doesn't make sense. They would have to aim the craft at where we are going to be in X years. X being the duration of the voyage.

Come to think of it, even if they were aiming directly at where we are now I would assume the light source would still be occulted regularly by everything between us and them.
The trello UI is also great. If you don't need the back-end features of something like Jira, trello's limited functionality greatly reduced the friction to tracking your activities.
I agree, the yellow/green/red is rather difficult to distinguish. Aside from altering the colors, it could also use different symbols. In general, it's good to have multiple distinguishing qualities (e.g. color, shape, texture). This helps make things more distinct for all users, not just those who might be colorblind.
> 120 divided by 5 = 24. Not bad! 24 mph is only a bit faster than the speed at which experienced parachutists land.

Better yet, just put your hands in front of you and land on all ten fingers. Then it's only 12mph. /s

In reality your entire body is moving at 120mph, so you can't divide the forces in this manner. This a PSI problem. Total inertia distributed over a given area. And the results are much less favorable.
I'm stuck on the third floor. It's just a room without any exits.
Using Tidio Chat. Seems okay so far. - http://tidiochat.com

Edit: Misread the question.
Internet warriors: inside the dark world of online 'trolls'
I think Buffy doesn't age that well, really. Most anything involving Angel is especially bad.
come to Sweden, we got lots :)
Really? All my girl friends who've been to Korea (even the Korean ones) can't stand it at all. I wonder if it's different for white American men vs minority (incl. Korean) American women.
As others have said here: if you don't see it, that should tell you something. The lesson isn't that minorities don't talk about their own issues.
While I appreciate your linguistic relativism, comatta is just not used: http://english.stackexchange.com/a/151261
I haven't seen that one either... Got a source?
Since moving away from the south east where my seasonal allergies were terrible I've actually used hot chillies instead of allergy meds. My symptoms are mild enough that the flushing of all the mucus is enough to keep them at bay for a week or so. It's been wonderful for me since every allergy or antihistamine puts me to sleep so it was difficult to function if I had to take them.
Why is it embarrassing for YOU personally?
Right, even if there are many, would you be able to justify keeping sickle cell? There was even a recent post on HN about it (thought I can't find the same link here's a jist [1]).

People will probably benefit from some type of cure as opposed to trying to save mutation that causes extreme discomfort (maybe death). I totally agree with importance of variety but i think it's equally important to understand and revert some of these unwanted mutations.

[1]http://www.acsh.org/news/2017/03/07/did-gene-therapy-cure-si...
2016 follow-up from the same "I regret I did this" person

https://blogs.msdn.microsoft.com/ricom/2016/01/04/64-bit-vis...
Freedom is binary?
Yup. Often times it's not a matter of whether or not they're "smart" or "self-aware", like I see being argued. It's just a matter of not feeling confident enough to demand more. This holds especially true for engineers I've met in the games industry. The games industry treats their engineers so poorly in terms of compensation that often when I encourage my friends in the games industry to demand more, they're often afraid to because they believe they'll have their job offer rescinded for demanding more.
In fairness to the author there is this text in the conclusion:

> Hindsight, of course, is 20/20. While I’ve spent most of this post talking about Trello’s missed opportunity, we shouldn’t forget that building a SaaS business that’s worth over $10M, let alone one that’s worth $425M, is a huge accomplishment.

Ignoring the ROI question for Trello investors/employees, I think it's fair to portray Trello as a "failure" if the goal is to build a large self-sustaining independent business, especially if it's true that they "had to sell" rather than stay independent.
9 cybersecurity tips for the mildly paranoid (plus 4 for the truly anxious)
How do you create a hash table where the value is an action that depends on the type of the value? The best you can do is something like Dictionary<Type, Action<object>> and use casting in the action, but that's much worse than C# 7.0 switch.
I'm curious whether this'll change when the NBN is more prominent. Does anyone know what their peering policy is/will be? I had a look around but couldn't find anything.
Right, it is like going to the gym. Doing it with a buddy means that each of you can take a turn at motivating when the other is tapped out.
If the tactile experience means that much I'd think you'd be too pissed to read anything from the past 40 years or so except from small specialist publishers. Even hardbacks now are mostly cheaply made disposable products, with whatever money that goes into their production apparently wasted on the dust jacket.
$450M... for a todo list. #perspective
High praise indeed, Strange Loop is developer 'crack' :).

I'll check out their videos.
Cloudflare is unquestionably a source of pure, unencrypted traffic for the govt.

Does anyone remember a few years ago when Google found out through leaks that the govt was wiretapping it's private traffic between datacentres?

What makes you so naive to think that the govt isn't sniffing every single page on cloudflare?
>he's not giving out-of-this-world prices, but he is losing money here

Note that the quoted price of $250/kWh was given at the pack level (just the Powerpacks).[1] So the total project cost should be expected to exceed $25 million after including shipping, tariffs, site preparation, installation, bidirectional inverters, and interconnection.

>build surrounding hardware, AND install it in 3 months

The nice thing about the Powerpack is that they need very little surrounding hardware. The units are rated for outdoor installation, and they just forklift into place to a concrete pad. A group of Powerpacks (4-8) shares a common bidi inverter, which is wired to the grid interconnect on site. Done.

The obvious thing to do would be to construct a building to house the packs and protect them from the elements, but I'm not sure that makes economic sense. These are exothermic devices when operating, so a big challenge will be cooling and ventilating the building. And if you're making a building just to spend capital and energy to ventilate it, was it really worth it to enclose weatherized equipment?

It might make sense in hot climates to put a solar "carport" over the batteries to shade them and reduce cooling load. Tesla has one that's supposed to be cheap to install.[2]

I expect the economically "right" answer (open air install, solar canopy, or prefab building) depends on local climate, expected battery duty cycle, and financing. Not to mention factors like your boss saying "100 days or it's free." ;)

>he needs to get about 1% of yearly global li-ion battery production to Australia

In 2013 Tesla gave global production as 34 GWh of cells.[3] 100 MWh works out to 0.29%, and I don't expect cell production has gone DOWN since 2013. So if you're looking for an order-of-magnitude, 0.1% would be less wrong (in both the multiplicative and the additive sense).

The completed Gigafactory is expected to produce 150 GWh/year, so this is only 0.06% of that. Unfortunately I haven't seen reliable numbers about the production volume at present (with about 14% of the planned 13.6 million ft^2 footprint completed, and probably half of that outfitted for production). I naively estimate the Gigafactory is currently producing at about 2% planned final capacity, so 100 MWh represents around 12 days of production.

[1] https://twitter.com/elonmusk/status/840096176678420481

[2] http://www.solarcity.com/newsroom/press/solarcity%E2%80%99s-...

[3] https://c1cleantechnicacom-wpengine.netdna-ssl.com/files/201...
Ah yes, my favourite tequila ;)
I think the parent commenter was requesting an itinerary without many temples ("temple-lite" → "light on temples"), rather than suggestions of temples to see!
Some context: this was published before the Wikileaks Vault 7 release.
Regarding bread, maybe relief is not the right word... bread will absorb the greasy substance and prevent it for further irritation.
yeah i'm on your side. I randomly generated a password one time that ended up with 3 repeated characters. I used it because, hey p-random is p-random i'm not gonna argue. Unfortunately the site it was for rejected it.

I've since had to change my random generator to avoid 3 of a kind, which actually makes it less random/secure i believe.. pruned some branches off of the search tree.. especially since i've now told everyone ;)
Well, now I feel dumb. I should have read beyond the abstract before commenting!
Its like bejeweled\candy crush. You select two or more adjacent colors to perform an "attack".

The "attack" will be one of four choices: You attack, you attack with magic, the enemy attacks you, the enemy attacks you with magic.

So the optimal solution is: Maximize the attacks that benefit you while also picking attacks that either lessen the damage you take OR choose damage against you that set you up for bigger patterns on the next turns.

edit: looks like is can get deeper too. For example, bats have no mana and cannot attack with magic so it is a nice way to move some blocks without taking damage if you dont have any moves.
The measure of success as a function of how far you've fallen is basically constant throughout and then suddenly changes to 0 (or -inf, or whatever).
How generic is your email address? This has literally never happened to me (to my recollection).
I love this guy!
I see thanks for the clarification.

I guess I don't get why it would be an S shape even if it's a perfect-circle orbit or an ellipse flattened out (side view). Yeah I'll have to read up on that.

edit: not sure if this is related, I remember doing this thing when I was a kid, you'd spin a globe and trace a pencil straight down (a lonitude line) and it spiral out (the drawn line). To simulate Coriolis effect

edit: Oh I see depends on what it's aligned to, (equator) to create the sinusoidal look... reminds me in calc or engineering creating diagrams/charts (maybe beams and moment/force diagrams) ahhh... sucks when you don't use something and you forget. In calc you did something with max/mins and this determined the concave/convex of a curve on a graph. Ahhh rambling sorry.
> By the way, a great way to relieve the "pain" is by eating bread

Bread does basically nothing; dairy is generally the most effective food (specifically, the casein protein in it apparently helps, as apparently does the fat) to mitigate spiciness (sour cream or yogurt are popular forms for adding to spicy food for this purpose.)
Activision was the first third-party Atari 2600 developer, but they didn't have to reverse-engineer the system from scratch -- they were all defectors from Atari. They did invent plenty of nifty tricks, though.

One podcast talks about Imagic, another VCS third-party developer: One guy, Bruce Pederson, was amazing. Without any documentation whatsoever, he attached an in-circuit emulator to a VCS and reversed the entire video architecture - including the special registers that doubled or tripled the sprites along with the requisite code timing issues. Took him two days to do it.

Parker Brothers used existing carts to inform their efforts: The 2600’s zany graphics chip was the key thing there. My first contribution was to write a disassembler for already-published cartridges. When analysis of the circuitry presented ideas for how the sprites and background worked, I wrote small test programs on the 2600 to verify our assumptions. With these combined efforts, we figured out how everything worked in a few months.

[1] http://2600gamebygamepodcast.blogspot.com/2014/02/q-with-ima...
[2] http://www.retrogamer.net/retro_games80/the-making-of-star-w...
IMHO you're missing the point. Sure many of us want to get rich, but probably more of us want to built a profitable, sticky long-term business. The article makes it clear that they didn't succeed as well as they could've in building a business. Getting somebody to buy you doesn't mean you created a business. The benchmarking of business achievement gets even murkier considering the notoriety of Trello's CEO, Joel Spolsky. It's the same issue as with Path's $100M or Slide's $200M exits, which also featured prominent CEO's with products of dubious business value.

RE: Trello, e.g., see the part in the post about "Trello's value proposition". Their $5/month Gold plan was really poorly thought out. Many other areas, again as articulated in the article, we're also not well thought out in terms of building a sustainable, profitable business. Signups != locked in, paying, happy customers.

> The 2013 blog post that announced the launch of Trello Gold highlighted three main reasons users should pay $5/month for Trello:

> Customizable board backgrounds

> 250-megabyte attachments for each card in Trello (vs. 10 megabytes on the free plan)

> Stickers and custom emoji
I've built (and continue to) a lot of companies using Rails. I also do Swift on iOS and have been playing around with Swift on the server since last year.

I have some friends that have an idea and I'm going to help them build it. So what do I use? The fast, low memory footprint of Swift?

No. I use Rails. I use bootstrap. I don't make a JS only frontend with api backend (Turbolinks works fine). I use what makes me productive and what's gets the first rev out the quickest.

For hosting, I put it on my Mac Mini (in my living room) via VirtualBox, with the same Nginx proxy I use for all my projects. I have no problems with scaling because I don't need to. Cross that bridge IF I get there.

I went through a number of years trying the latest and greatest frameworks, aws configs, etc. None it mattered to my projects. It did help with day jobs, but that was it.

Some other poster here was right when he said tech is about 10% of your business. There is so much other stuff outside of building your app/site and having analysis paralysis is gonna stop you dead in your tracks.

My advice (as many on HN have said before): go with what you know, don't over engineer, ship early and often.
thanks for your suggestions KabuseCha :)
Ask HN: How much do you pay yourself?
Say if you had a startup seed funding of $80k for
maintenance costs of 2 years.

As a founder/CEO, how much would you pay your self?