skysight-inc/HackerNews huggingface dataset:
Don't play devil's advocate. Only advocate positions you believe in.

2) is countered by the fact that antibiotics are not needed by most of those people; and antibiotics don't reduce the severity or duration of the disease by much.

See for example conjunctivitis. Most people attend their doctors and expect to be given antibiotics. This is the case even though doctors find it hard to tell the difference between bacterial and viral conjunctivitis; and that antibiotics don't reduce the severity of the illness, and only reduce duration by one third of one day.

http://bjgp.org/content/early/2016/07/05/bjgp16X686125
Time Perception
When not to write benefits-driven marketing copy
Comments like this never fail to make me smile:

+ // Don't do anything if the process_path length is > PATH_LENGTH
+ if (strlen(process_path) > PATH_LENGTH)
+ return;
That matches my experience. I was familiar with domain and range; this thread is the first time I've heard the term "codomain".
Ask your doctor to sign up to antibiotic guardian style schemes.

Ask your doctor what happens if you don't take antibiotics - are they really needed for this illness?

If you do get antibiotics take the full course. Take them correctly, according to the instructions.
Alexander Fleming gave the following warning, way back in his 1945 Nobel speech:

It is not difficult to make microbes resistant to
penicillin in the laboratory by exposing them to
concentrations not sufficient to kill them, and the
same thing has occasionally happened in the body.

From page 93 in https://www.nobelprize.org/nobel_prizes/medicine/laureates/1...

BBC did a very good radio segment about the penicillin discovery in their "50 Things That Made the Modern Economy" radio series: http://www.bbc.co.uk/programmes/p04pfn2z
Of course they do, because they increase the cost of doing business there.

And it does it with a far lower cost to sovereignty.
Why not instead test for it, and vaccinate those without it? Would getting vaccinated for it if you have some strain even hurt? Why not vaccinate everyone, then?
sublime does have 'goto definition' and 'find usages / references', but they're not the same as peeking. They both open the target file (& changes the files you were viewing), whereas peeking just let you stay where you were.
It's been a great era for condensed matter physics though. And the recent revolutions in nonequilibrium thermodynamics (fluctuation theorems and generalizations of the second law) promise an exciting time ahead!
It doesn't conflict with the Constitution and this is a common misunderstanding by laymen about how the law works in the USA.

"Case Law" vs "Statutory Law" is the name of the game here.

To not beat a dead horse: every single decision made by the Supreme Court is effectively in the Constitution and the Bill of Rights.

Any part of the Constitution can be interpreted, modified, or nullified by a decision of the Supreme Court.

So, when the SCOTUS decides that an exemption against prohibitions against unreasonable search and seizure applies at the border, you can be assured that they view it as "constitutional".
I remember in 2000's there was a sex quiz that spread like a worm where you answered personal questions. My friend sent me a link and of course I answered all the details for him to read. Then I sent my link wanting for revenge etc. I can't remember what was my motivation to answer, maybe I was young and just thought it's cool. I do know what was the motivation to spread it further...
I'm a parent with two children living in SF.

Before I had children, I had no idea how difficult it was going to be, even putting aside finances. Most people without children just don't get how much more difficult ordinary life becomes. There is a deep reason that the "boring" suburbs beckon.

Yes, the schools and the lower housing costs are a part of it. But there's also just the easier lifestyle, where you don't need to compete as much for everything. Parking, sidewalks, aggressive cars, daycare, schools, a seat on the bus, and very much avoiding crazy people who might harm your children.

It is extremely stressful to walk your young child across a busy intersection in SOMA where a driver is aggressively trying to turn, where a crazy person is screaming at the top of his lungs, where a street that smells of urine awaits you on the other side.

Putting SF aside, it's extremely difficult to maintain a good relationship with your spouse when a demanding job takes up a huge amount of time, and when that job seems like a vacation compared with the weekends with the kids. Almost universally every parent I know says that going to work on Monday is a relief, the beginning of their temporary vacation from the intensity of nuclear family life.

The children themselves create the vast majority of the stress. Parents need environments that help reduce that burden, not merely keep inconveniences at bay. At our school the #1 wish of parents, by far, is for faraway grandparents to move nearby and help. If they could afford it. If they could survive in this city hostile to the elderly. If they were willing to give up their comfortable retirement travel adventures to shoulder some of the burden. Very, very few have this arrangement in SF.
Is that a zero sum game? What happens if you add a heat source to the model?
There's three reasons for using antibiotics in livestock:

1. Growth promotion
2. Prophylactic treatment (what you're suggesting)
3. The treatment of actual disease

Those go from the most to the least problematic - but I was mostly addressing the idea that a decrease in antibiotics would result in more animal products with bacterial contamination. For #1, that's not true, and for #2 it's not linear (infections in animals don't necessarily mean contaminated food products).

When we talk about reducing antibiotic use in livestock, it's usually focused on #1 and putting #2 in the hands of vets (prophylactic treatments when there's actual risk of disease). Rarely do we actually suggest banning #3.
As Frank Herbert put it in Dune, fear is the mind killer. Only a small subset of humanity will have clarity of mind while the fear response is in action. If we look at history, more wars have been fought over some demagogue preying on the fear response of the public than anything else.
What are even the use-cases for the vaccines which don't protect against as many as possible? Why is such a product allowed to be on the market?
Try Gentoo (again:).
If that's the best argument they can come up with, it's clearly a terrible treaty. The loss of sovereignty, like being able to set your own IP and working condition laws, far outweigh that benefit.
> there would be significantly less surgery if there were more prevention.

True but that's a considerably diminished claim from the OP's, which was that all surgery is a sign of doctor failure. Also, the unscientific treatments they linked to would do nothing to prevent heart disease, and may even discourage patients from seeking care that can help them.
Package manager repos like Cocoapods and Gentoo's ebuilds are going to have a high contribution rate because they are updated every time any single one of their packages is updated.
It is much harder nowadays, but around 2000 every Hotmail account was protected only by these easy one sentence questions. It was trivial to open accounts if you wanted to. Favorite football club, pets name - - just ask the target. I remember I was young and was wondering why is it so easy to 'hack' Hotmail.
Cows can have pretty intensive levels of antibiotic resistant gut flora.
Right, I think we agree. It's not a sunk cost fallacy. It's more sink cost signaling or something.
> This shit is important for increasing investor confidence in countries with nascent court systems and political systems used to corruption and nepotism.

Isn't it up to a country to make itself attractive to investors, i.e. by not pulling all that shit?
Yes, you're right in that adopting verbatim the philosophy of ancient China isn't a perfect fit for our modern world. But the sentiment - that doctors should make more money when we're healthy vs not is one worth thinking about. Currently the entire medical field is reactive - you get sick, you get treated. I've never heard of doctors administering preventative care. We don't have a profession that fills the niche of "I'm feeling fine now, but I want to take the steps necessary to prevent things that might ail me in the near future".
It would be nice to show repos from different date using a history plot
"Hey, this might protect you against prostate and some other nasty forms of cancer which can be caused by this sneaky STD that tons of people have which is typically asymptomatic (and thus why most people don't really know about it)." If a 12-14 y/o doesn't understand that + the implications, I'd like to fix sexual education until they do. Is it really that difficult as a parent to explain such a thing? I had "the talk" when I was around 10, and I read a lot on my own over the following years.
Yes, the biggest hindrance to python3 is the fact that python2 is a good language. It's very rare to come across a case where you can tell someone, "if you were using python3, this would be so much easier/more performant."

Most of the migrations I have seen have been because of a stick rather than a carrot (e.g. this library we depend on is dropping py2 support). It's definitely the case that the move has only been as successful as it has because of the (relatively) unified effort of popular open source library authors to switch common dependencies.
This. Especially for antibiotics, there's not really many levers you could use to manipulate the efficacy of a new drug - all of that is driven by the mechanism of action. There's really no "Lets make it 25% less effective..."
"You're talking out of both sides of your mouth right now."

This is true. Is that a problem? Is it necessary to resort to binary thinking, which always means buying a whole package of ideologies at once just because you agree with one aspect of it? I won't do that. I actually think this is a source of a lot of evil.

"That is simply not true. Pointing out the fact that globalism actually does cause the quality of life (in the short term and sometimes long term) of certain demographics to suffer is a true statement."

My issue is that I agree with you on this. So I am not even sure what we are arguing about. I actually thought this got clear even in my post.

But acknowledging the downside of globalization does not automatically lead to the conclusion that the way to fix the problems is to go back where we came from. Or does it for you?
I somehow doubt they've banned it in Singapore, Korea, Taiwan or China.
Here, some more info, this time, by CBS.

https://www.youtube.com/watch?v=l5AxV1SrTkE
I tested this with Chrome twice - just as a regular tab once and once with a VPN in an incognito tab. They produced different Browser Fingerprints for some reason. Is this supposed to happen?
> a new antibiotic is guaranteed to be a commercial failure

This is not axiomatically true.
Just got an evil idea.. You can target on fb and Google by email lists. You create some stupid web app with questions and promise something in return, a prize, or make it worthwhile to play and target them with all the security questions email accounts or whatever might ask. Could be that this is being done for phising already if the victims are being targeted specifically and don't have 2fa.
For Buffet's take on this argument, see https://en.m.wikipedia.org/wiki/The_Superinvestors_of_Graham...
The impression i have of this "arab spring" is that bad what harvests in Russia was the instigator, but that the net acted as a massive pacifier.

This because via the net people could keep up with what was happening without actually being pulled in. Only when the net connection was cut did the likes of Egypt flare up. This likely because people now had to get out on the street and talk to their neighbors to stay informed.

I do agree though that the middle east seems to be having its own 30 year war going.
You say that, but put in the situation you'll find your bravado is significantly lessened.
Maybe an algorithm that ranks based on number of unique contributors in the past month or so?
You seem to be assuming some of these things aren't being done.

Antibiotic stewardship is a major push in most hospitals, and there are national level evaluation programs for antibiotic overuse.

But, as people have noted, there are other countries also driving usage (for example, China heavily uses colistin, while its a drug of last resort in the U.S.), and once resistance is established, it's very hard to make it go away.
I used to have delivery problems (throttling errors caused by another customer) sending messages to Microsoft related domains (hotmail, msn, live, etc.) when using MailGun.

There was no progress at all when discussing this topic with MailGun's support so I created another account at PostMark [1] to choose provider depending on recipient's domain. No more problems when sending messages to Microsoft related domains.

Anyway, "silently discarded" sounds like you need to put in place DMARC reports [2] to troubleshoot what is going on there.

PS: I chose PostMark because I like its online documentation. Currently a happy customer, not affiliate at all.

[1] https://postmarkapp.com/
[2] https://dmarc.postmarkapp.com/faq/
>And if you're starting a new project, why not write it in Python 3, which has first-party support?

Because you're importing big legacy python2 libraries.
They can use a $5 wrench attack. Breaking encryption isn't something that happens in the real world.
The conventional assumption is that antibiotic resistance comes at a substantial fitness cost, so in the absence of selective pressure, susceptible bacteria will out compete them.

This is a nice, clear, elegant theory.

It hasn't worked in practice. Community-acquired MRSA rates have risen, even as the selective pressure from antibiotics has declined, and the general observation is that the fitness cost is nowhere near as big as we assumed it would be.
>Of course they do, because they increase the cost of doing business there.

This misunderstands what incentives are at play for politicians with low accountability in developing countries. The cost of corruption is borne by these investors and domestic consumers, but the benefit of it is entirely concentrated in the political class. Therefore the opposite incentive exists, and the system becomes more resistant to any changes towards more inclusive institutions.

>sovereignty.

Meaningless buzzword. If a nation no longer favours the basket of benefits and obligations, it is entirely free to leave.
Seems to me like a "problem" only in the sense that one wants to leech data connectivity while out and about.
> So, years later, the only thing I'm surprised at is that Python 3 actually caught on to the extent it did.

Well, it's been over 8 years. And we've just reached the point where nearly all libraries are available in Python3, and Python3 is recommended for starting new projects.

Python3 was also a very unconventional backwards incompatible change. 90% of the incompatibility came from "you must correctly and carefully handle unicode vs bytes". All other backwards incompatible changes were trivial in comparison, almost fixable by search and replace.

And "careful handling of unicode vs bytes" was something that you already could do in Python2, and should do in Python2, but weren't forced to. If you did, then upgrade to Python3 was easy. If not, then you had a massive testing and refactoring problem on your hands.

I would not even see it as a language change, but would compare it to C and C++ compilers turning -Wall -Werror on as mandatory flags in the latest release. It would be sort of "good for the ecosystem" in the long term, but would also be a lot of effort for people with legacy codebases.
It doesn't change that Trump did the right thing by pulling out of TPP. He may make poor decisions at other times, but it's still a case of credit where credit's due.
Thanks for having the courage to ask about it in a honest way. Sounds like you realize Wikipedia is never a source; It's a perception management platform. Checkout the revision history for the Gulf of Tonkin for example... Their 9/11/01 omissions will themselves will be the subject of future psychology (and PSYOP) books.

http://s3.amazonaws.com/nasathermalimages/public/video/Prete...
> I've never heard of doctors administering preventative care.

You've never heard of preventative care visits? Annual physicals? Baby wellness exams? Vaccinations? I'm incredulous.
A few important points about antibiotic resistance (as far as understood by a lay person that likes to read articles on the topic):

1) Resistance is inevitable. It doesn't matter if everyone finishes their prescribed treatment or not, bacteria will develop resistance to antibiotics one way or another.

2) Antibiotic resistance comes at a cost to the bacteria. In the absence of antibiotics, bacteria will lose their resistance. It is pretty unlikely that you will get infected with antibiotic-resistant bacteria when you bruise your knee in the dirt.

3) Multi-resistant bacterial infections mostly occur in a clinical setting, where people are especially vulnerable to infections (people on a respirator, people with a central venous line). You can prevent multi-resistant infections just like you prevent normal infections: Use sterile gloves, isolate people, follow procedure protocols precisely, etc.

Multi-resistant pathogens are a problem, but it's far from the doomsday scenario painted in those "it's the end of antibiotics" articles.
And in the process walking all over various security best practices?

And was there not a similar security snafu involving iPhones broadcasting past ssids every time they tried to connect to a access point?
I suspect that Ruby also benefited from having a comparatively young community. There are folks that used Ruby before Rails, but the majority of Rubyists only started in 2006 or later, so they are used to the faster replacement rate of modern Open Source and didn't have so many legacy codebases to worry about.
18 months is the time until any resistance is found, but that doesn't mean we hang up the antibiotic. We do susceptibility testing, we use higher doses, we use combination therapy, etc.

Resistance is a continuum, not a binary state.
This is wonderful! The next time anyone asks why Python 3 is better, I'll just link them to this project's README.
Why not just actually audit each app? Surely there's a way to diff the changes and only have reviewers consider those. For issues like the one cited (free trial CC requirement), that seems very easy to check, especially if the payments are integrated with Apple. So v1 didn't have any CC entry stuff, gets approved + catalogued by Apple as having the free trial w/no CC attribute. V2 comes along, reviewer sees visual diffs, ooh hey there's a CC entry form now, re-check trial flow, reject v2, record this.

I'm definitely oversimplifying, but is that not at least close to how it works?
Calling JS a functional language is like calling a tricycle a sports car. Apart from first class functions it has nothing any decent fp language has, like: partial application, currying, immutable data structures (it does not even have decent non-immutable ones), etc. You can work around some of them (albeit painfully) but why would you do so if you can use a real fp language?
Every country's leader will tell foreign investors that there is no chance that their business will be regulated differently than their nephew's competing in the same space. Investors can trust them a lot more if the country's continued enjoyment of increased foreign demand for their exports lies in the balance.
I am glad you are finding the posts useful. It is always good to know that someone has a similar to-do list as it confirms that you are at least on the same page as other people :)
I would guess the Elm is used more often than Scala.js. But then again, I have no data :)
What if you don't hand over the password?
Well, in this case it's not that I'm saying 'yes, holding onto a personal supply of antibiotics is the right answer', it's that I'm saying there is a real problem to which the official advice offers no solution. Conjunctivitis is certainly a good example. As for what would be a solution, I think it would be helpful if you could get basic medical advice and an antibiotic prescription over the phone. (To the person about to point out the potential downsides of this - yes, I'm aware of them – but what's your better solution?)
I sincerely hope this is true, but 10-15 years ago high throughput computational screening was going to usher in a new wave of targets and molecules that acted against them, and we were going to unlock who new families of antimicrobials.
So going forward for corporate users it's going to be either Linux or AIX considering the way HP-UX, Irix and now Solaris is slowly seemingly heading to.

What I'd really like to see is harnessing of the knowledge, principles and methods of solid system management and stability that have been built and field tested on Unix platforms over the decades. This would benefit whichever platforms remain (and are created/update) going forwards.
I can't believe you get down-voted for stating the obvious; so many otherwise-smart people jumped on the conspiracy bandwagon for this one. Lots of bad parts to TPP, but the "secrecy" was not one of them.

You are being distracted by irrelevancies if you think this was the main issue. And probably quite foolish if you think democracy means 100% of people give their input to 100% of decisions.
The problem is that we currently oppose the 2 views, and people defending one discard all benefit from the other.

But it's true that you are happy to get surgery in case of a grave emergency, with heavy drugs and a strong hopital system. It's also true that the current most used health system is actually very bad at keeping people healthy.

But no, all pharma related practice is not a z-serie drug dealer plot. And no, all alternative health practice is not hippie voodoo trying to cure cancer with placing hot stone on your third eye.
> But there is no guarantee that a child will get in a selected school. And once the lottery has filled all the slots, those soon-to-be kindergartners who get into none of their choices are offered a place in a school with open positions. Proximity to their home and transportation are considered.

Is there _any_ system that can "guarantee" that a child will get in a selected school when there are big demand-supply gaps?
As someone who refuses body scans every time and have never had anything happen (Other than a brief secondary that involved waiting for 5 minutes and a "Sorry, you're good to go"), I don't think refusing the full body scanners has anything to do with it
> I've never heard of doctors administering preventative care.

"Making every contact count", a UK initiative to make sure that doctors[1] use every opportunity to promote smoking cessation, alcohol use reduction, weight loss, and other lifestyle adjustments.

http://makingeverycontactcount.co.uk/
No, they can bar you from entry for any non-compliance.