skysight-inc/HackerNews huggingface dataset:
Fred, James and I are in the thread and happy to answer any questions about the product and how we built it. There's definitely more detail than made sense to include in the blog post.
Only if dormant cancer cells get passed from cured parent to child, which generally should not happen.
This would be amusing, but is basically how a retainer works.
i get your point, but connecting to a random country won't be of much help though.
I'm not sure if this is in-use anywhere, but it may lead to better "cache eviction" policies. Saying something is immutable has different implications than saying "I want it cached for 10 years".

The former would allow a browser to apply some heuristics and say for example evict something from the cache when it hasn't been referenced on a page for the last 5 times you went there (the assumption being that it was changed and the new resource is taking over in it's place).

That can lead to things being held in the cache for longer without having to use a straight "oldest evicted first" kind of method which can lead to thrashing if the cache size is too small or some resources are too big.
I absolutely agree with you. Taxation is, by definition, wealth redistribution..and theft by people in power!

I think the more important question is what are we spending taxes on? and why does it have to be decided by a bureaucratic monopoly that is above the law a.k.a. government? Shouldn't we have a choice in how we allocate our own resources? Is it not our own time and labor that we use to produce? Why does that belong to anyone else?

I'm not against helping others in need. But the important distinction is that is should be by choice not from coercion.
Show HN: My Django book, Hello Web App, is now free online
A couple of years ago I wrote Hello Web App (http://hellowebapp.com) to teach beginner Django web app development. It's aimed at non-programmers and designers, and walks folks through building and deploying a basic web app.

I'm working on my third book to teach web design fundamentals to programmers (Hello Web Design: https://www.kickstarter.com/projects/1868398473/hello-web-design-design-basics-for-non-designers), so I've made Hello Web App free online during the Kickstarter campaign for the new book.

The full Hello Web App tutorial can be accessed here: http://hellowebapp.com/tutorial/intro/

Also, I'm happy to answer any questions about writing and self-publishing books — I've probably made about $20,000 lifetime profit on the two Hello Web App books overall.

Thanks all!
Could stem cell therapy be used to potentially improve existing muscular or neurological connections in normally functioning individuals? Kind of like a whole-body neurotropic.
You typically do a 302 redirect AFTER the POST authentication. This feels more of a publicity stunt more than anything. It might affect very few use-cases. Bulk of the requests on the web are GETs anyway.
Still think trump' twitter account will get hacked.
If I understand that the article is claiming a new treatment could cure cancer for $4000, then this is orders of magnitude cheaper than all the combined treatments that are administered now to treat cancer.
grep -rl 500 .

wasn't accepted. Am I wrong or is it wrong?
Really? The article implies that the whole point of Immutable is that the browser won't revalidate contents.

(Also, "304" is an HTTP response code -- "Not Modified" -- not something the browser sends.)
Does Windows handle multiple monitors with different resolutions well? I haven't really tried it before.
Your list is missing a very important advancement from 1937:

https://en.m.wikipedia.org/wiki/A_Symbolic_Analysis_of_Relay...
My apologies for being disrespectful. I should have said "neglected to use" rather than "doesn't know how to use".
The treatment also requires a bone marrow transplant (which requires destroying the patient's immune system). It's a lot of medical care.
I don't think an offer amount was made. As far as I can tell there is no significant money or even organization in the group of people that are doing their best to manage the project. They're still looking for a way to formalize. I would read this as that stakeholders have not been eager to donate the RethinkDB IP to a foundation, so perhaps there either are commercial parties interested in the IP, or the stakeholders think there might be.

This is all conjecture though, unfortunately besides these meeting notes there is no record of interactions with the RethinkDB stakeholders.
There has been a lot of uplifting news coming out of stem cell and gene therapy the last couple of days. :)
Review: I Tried These 7 Productivity Hacks from Business All-Stars
fun, although I did cheat a bit on the corrupted text and pulled the expected output from README instead of the input file :)
I read the comments quite a lot, particularly now that you can hide whole threads and really focus on threads you are interested in. I think its been great for keeping a view on the lower rated threads that are more relevant to you interest. There are often some real gems at the bottom of the page.

There are commenters I like and ones I dread, I've experimented with extensions to allow notes and highlight colors / imagery to make it easier to find comments and prompt my poor memory for some information about the poster. If I ever get something I like, I'll release it, but the first efforts have been ick.
Once personal data is collected it could be abused or used in a way you object to. The abuse could be perpetrated by a third party who got access to the data legitimately or illegitimately, or by an employee of the company, or by an owner of the company.

As the target of such surveillance and data collection, you just never really know how that data will be used or who by. It's optimistic, to put it mildly, to expect that data will only be used for purposes you don't object to by good people with the best intentions.
Other commenters are right, licensing was a big factor, because the 1990s were marred by a few high-profile events where patents on popular formats were suddenly enforced [1]. These events led to the PNG format being developed as an alternative to GIF, and Vorbis developed as an alternative to MP3.

By the time JPEG 2000 rolled around, wariness of patents was well-established.

On the technical side, JP2 produced unsightly ringing distortions much more noticeably at medium compression ratios than JPEG did while also blurring detail, while JPEG would only experience ringing around sharp transitions, and would get blocking artifacts elsewhere. For some people, JPEG's blocking would impact a sort of 'fake sharpness' in the image, while JP2 would produce a blurry smudge. Dark Shikari, longtime dev on x264, wrote about this phenomenon [3], which also adversely affected early H.264 encoders and made them look worse compared to ASP (like Xvid), despite former being an objectively better format.

[1] https://en.wikipedia.org/wiki/GIF#Unisys_and_LZW_patent_enfo... [2] https://en.wikipedia.org/wiki/MP3#Licensing.2C_ownership_and... [3] http://web.archive.org/web/20141124213159/http://x264dev.mul...
If you don’t tell the browser in some way where your response ends (with Content-Length, chunked, or HTTP/2 [?]), you can’t reuse connections, as far as I know. If that’s the case, you probably don’t care enough about performance to use `immutable` anyway.
After an accident such as this, is there a point at which it's too late to perform this type of injection? Asking for someone in a similar situation.
https://news.ycombinator.com/lists

Missing from that list:

https://news.ycombinator.com/classic Front page with votes from older accounts

https://news.ycombinator.com/over?points=100 Front page with posts over n points
The Coin Toss and the Love Triangle
Oh, the book is awesome. I mean the fact that such a book had to be written is a pretty rough statement about the language.
This is propaganda. Spending on research and development at private pharmaceutical companies is dramatically eclipsed by marketing and sales spend.

https://www.google.com/amp/s/www.washingtonpost.com/amphtml/...
Technology products often decrease in price. But for cancer treatments it's the opposite. New treatments used to cost $4,500 a decade ago and cost $10,000 to $30,000 now.
Meant to say that there's no conditional with immutable. Corrected, thanks.
Could you elaborate on this, please? It's contrary to my intuition, and I respect your opinions on the subject. Having an auditable hardware token shouldn't preclude backup and restore? It still reduces the surface area for vulnerabilities to an object with no radio.
Show HN: Meteor-Now – Deploy MeteorJS (YC S11) Apps with 1 Line
Sure, I agree with you.
If only this would support PRs / code review with revisions ... !
As far as I know, only if you fall for the dark pattern nag. I haven't run in to this, either because I haven't had it disabled for long enough or because Microsoft buckled and removed it.
It depends. If the usual treatment for a terminal disease has big side effects and is unlikely to pay-off it might be more ethical to use a promising treatment whose effects are uncertain.

However, I expect a lot is known about chemo-only survival rates so it may not even be a legit criticism as you can compare the combination survival rate to the baseline. That said, n=2 is too small to draw conclusions.
I don't think a reasonable business person would see that hypothetical e-mail exchange as something to count on. I think the boss is just trying to guarantee he/she will have a good worker if the deal happens. An emotionally-invested person might consider the e-mail as an agreement, but such person shouldn't expect a worker to sacrifice his/her future opportunities for a risk like this.
Google's PAC, NetPAC, well predates the formation of FairSearch, by at least two years.
They do statistics a few times a year:

https://www.backblaze.com/blog/hard-drive-failure-rates-q3-2...
Use a Yubikey Nano. You could easily epoxy it in place.

... but physical access is game over no matter how much epoxy you use.
Using it without the knowledge of your boss, or as a boss by not evaluating points earned from such tools as performance metric, it may be safe to practice such tools though. :)
You need a larger sample size than 2 to differentiate between the odds of "success due to just chemo" vs "success due to chemo + x treatment."
Cache:

https://archive.is/ve28m
You are: grep matches strings, not integers.

grep -rl '500'

works just fine.
I have kept one off and on. I like writing using pen and paper. Given that I type much more quickly and I'm at a computer all day, a file-based journal is more pragmatic.

I wrote a simple script 14 years ago to automate the organization for me.

http://pastebin.com/pnWQemAf

I just alias a simple one letter command to "jour.py work" or "jour.py blog" and running it will open a file with a date-based name in my editor of choice. Re-running it on the same day gets me the same file.

This method has the advantage of a very organized, timeless format. The disadvantage is that it's on my local machine. Of course, a cloud based file store could be used, but there is no default encryption and there is no mobile option.
Favorited comments and stories are available from your user profile.

Note: Favorited comments and links are publicly visible.
Seth Lloyd (MIT) Quantum Machine Learning (2017 Winter Graduate School)
zsh implements something called bracketed paste mode.[1]

[1] - https://cirw.in/blog/bracketed-paste
Seems like a textbook case.
> Is author serious with this statement?

Whether or not this author is serious, there are many people who are deadly serious about this sort of thing. It's one of the main reasons that, for example, marijuana has been kept illegal despite the overwhelming evidence that it is less dangerous than either alcohol or cigarettes: legalizing pot is bad for established business interests. It's the reason that credit card transactions cost 2-3% when the technology to process payments for an order of magnitude less has existed for years. It's the reason "low fat" became a thing when sugar is actually much worse. It's reason you can't buy an open-source mobile phone. I could go on and on.
Sounds cool! I wonder if this will be with TensorFlow. If so, does the RPis videocore have any capability to accelerate such things or not out of interest.
Why would the browser need to reload all resources after a POST request?

Presumably, only the main (HTML) page should be refreshed and other linked items (CSS/JS/media) with high max-age (and no 'must-revalidate' cache control header) should use the previously cached content.
Only filenames matching access.log should be returned.

Unfortunately, since shopt globstar is disabled I ended up needing to do this:

grep 500 $(find . -type f -iname "access.log*")
The article says that this study requires the patient to be stable enough for an injection 13-14 days post-injury. That's not to say we know it wouldn't help, but that's what this study is looking for.
Your defensiveness about your preferred OS blinds you to the point I'm trying to make. There's a reason that there's an entire page on the ArchWiki dedicated to tweaking for HiDPI: https://wiki.archlinux.org/index.php/HiDPI

The fact is, it's not uniformly supported yet across Linux distros. Qt apps should theoretically be DPI-aware, but that's no guarantee either. See the various bugs filed against VLC, for instance: https://trac.videolan.org/vlc/ticket/17823

If your goal is to prove that it can be done, then I'm sure you'd be perfectly happy with KDE or KaOS in order to prevent someone from downloading an app that might not be HiDPI compliant.

But for the average person, it might be more trouble than it's worth. Or they might not like KDE. In which case, my recommendation that it might be better to stick with 1080P for now still stands.
Far more selfishly - you often get a few subsidy too.
> You can't just punch people in the face because they're Nazis

Sure you can.
Compassionate therapy basically means "it seemed super likely that these patients are on track to die, so even if this therapy is awful for them, you can't make the situation much worse, and we should take a shot at curing them."
> Automatically connect you to a random VPN in a country of your choice.

Country wouldn't be random in this case
Great! Sorry I didn't know whether or not to post to the root. I noticed you only had PLA and TPU materials. Is ABS in the works? My project required waterproofing and more strength than PLA.
$325/mo for residential water in Atlanta? That's nuts.

Here just north of Philly, we've seen water/sewer service go up substantially in the past 5 years, but it's no more than $50/mo IIRC.
Nitpick: it's $4000 per dose, and you're comparing to the monthly cost
Scientists create a part-human, part-pig embryo
You choose the country, it just selects a random VPN within that country.
I'd imagine 'immutable' but not recently used things will still be evicted from the cache at some points, when space is needed. There's no reason for them not to be, is there?

A browser can already apply different eviction policies to things with very long `expires`, I don't know if any do.

I'm having trouble seeing what this adds practically, too. I guess it's more of a clear semantic intent to say 'immutable' when you need that, instead of 'expires a long time from now'. Practically though?
There is not much info at https://www.cfa.harvard.edu/itamp/WinterSchool2017.html

Quick info gathering for the other videos in the youtube list

Paola Cappellaro (MIT)	Introduction to Circuit QED

Steve Girvin (Yale)	Introduction to Circuit QED

Wolfgang Lechner (Innsbruck)	Adiabatic Quantum Computing

Seth Lloyd (MIT)	Quantum Machine Learning

Misha Lukin (Harvard)	Three Lectures on Quantum

Science with Atoms and Atom-like Systems

Chris Monroe (JQI - UMD)	Atomic Qubit Control

Matthias Troyer (Microsoft)	The Quantum Future of Computation

Susanne Yelin (UConn & Harvard)	Photonic Quantum Information with Dipolar many-body Systems
Man Accidentally Makes $1.3M Buying a House with Bitcoin
No, the original sin was C's and it was the use of a separate "arrow" operator for accessing fields of a struct through a pointer. Other languages (C#, Java) successfully avoided that. C++ references allow templated code to be agnostic of whether an object is given by value or by reference, because the syntax is now more uniform.
You can choose the country by passing -c argument.

Example: easyvpn -c JP
We tried using Octopus (3 years ago) as part of our CI/CD pipeline and ran into a big problem with it choking on file sizes and handling all the bundled dependencies we threw at it. Eventually we just scripted MSBuild and archived them ourselves for retrieval when we needed them.
I'm on the iOS 10.3 beta, and for the most part, my iPhone 7 feels faster. Whether or not that is because of the new filesystem is unknown, but it is a welcome change nonetheless.

So far, I've yet to find out if the iPhone filesystem hierarchy has changed. According to crash logs, apps still launch from /Applications, processes from /usr and /var and so on. For some reason I expected it to change... I now realize it is based on the old UNIX structure, with of course Apple's modifications.
Good to see a manufacturing startup in YC! I'm currently a grad student in industrial engineering and have been working with geometric analysis for manufacturability for around 2 years now.

What types of analysis are you doing on the parts to determine cost? Slicing, orientation optimization, volume analysis, full toolpaths with estimated time?

Does your analysis automatically look at the tradeoff between injection molding and 3d printing for a particular design which was uploaded?

I noticed the current interface requires all parts to be in the same unit. Any chance of a per-part unit selection (while keeping the batch)?
The answers I came up with are in https://github.com/jarv/cmdchallenge/blob/master/challenges.... if you are curious.
Agreed. Patent and insurance reform are crucial.
Model Driverless Car Regulations After Drug Approval Process
I like how it can rapidly deflate and still be something practical that the astronauts can wear comfortably while indoors. Very clever. Almost makes me wish that we could move towards a society where fashion was irrelevant in consideration to function, and we could all walk around in multipurpose jumpsuits like this.
"avoid ingredients you can't pronounce"

I would definitely avoid dihydrogen monoxide.
That's a function of perverse incentives, rather than some sort of immutable truth. If there were stronger penalties for (e.g.) cartel-like pricing (e.g. TKIs), and more price transparency for the true costs of care (ibid), we might see less of this. Or if, say, the primary market for such drugs adopted a single-payer system where the payer negotiated on behalf of the patients, rather than on behalf of its shareholders.

Gleevec and Sprycel are the canonical examples of "competition makes the price go up" but if a single payer dominated the market and used this as leverage, it would be simple enough to just say "not at that price" and force manufacturers to play ball. The real problem is regulatory and legislative capture which prevents this from happening.
Thanks for offering! Any thoughts on supporting GitHub Projects?
I read that as a caution that these companies could try to fight this technique, or that it could face problems getting to market, not saying that it was somehow sad that these companies would face trouble.
thank you commentators for saving me before I wasted my time reading the article, this is why I love hacker news
I think that's not currently clear, I'd expect technologies such as CRISPR to have a far greater impact on enhancement of "normal" honestly. Some brain diseases are caused by the overriding of nuerons, so more is not necessararily better, for example.
Definitely, specifically concerning subjects that are high level such as crypto, compilers, language design etc.. There are subject matter experts here who give a trove of information for free on HN that I would easily pay money to hear at a conference or lecture. I particularly enjoyed the recent "Rust vs. GO" thread where local folks broke down the advantages/disadvantages of both languages without dissolving in a flame war.
https://news.ycombinator.com/item?id=13430108
No, they can't. To do so would introduce confounding variables in the inevitably unique way they treat their subjects, even if it's just knowing you're part of the experiments.

For maximum assurance of conclusions, such studies need to be double-blind: neither the subjects nor the researches who interact with them are to know who's taking just chemo and who's taking the new treatment.
Turing himself addressed this issue, and actually his famous 1936 paper talks about computing real numbers, not natural numbers. See http://cs.stackexchange.com/questions/35343/analog-computers... for a brief discussion. In short, we don't know of anything that an analog computer can do that a digital computer can't. If you think a bit about your point on precision, you'll see that "desired digital precision" actually covers a problem that is essential to the analog computation itself. In other words, try to think what "infinite precision" actually means.

But let me give an example that would make it more concrete. Suppose you want to build a computer that simulates the behavior of n bodies in gravitational interaction in space. It's obvious that with a digital computer, there would eventually be discrepancies between the actual system and the simulation (which would only grow). But now consider this: suppose that instead you want to do the simulation by building a "computer" which is nothing more than a copy of the original system (i.e., the "simulation" is composed of another set of n bodies in space). Is it possible to have this analog "simulation" more accurate than a digital simulation? The answer is no, because even supposing a true continuum of positions and velocities exists in the first place, in order to reconstruct the system precisely, you would need to pass an infinite amount of information to the "simulation", which is impossible.
Hey Jonathan, I'm interested exploring making mycelium media modules (how's that for alliteration?) for aquaponics. I've blogged about it here: https://blog.automicrofarm.com/mushroom-media-adventures-2e2...

I'll email you later today to discuss further details. Thanks!
You could also look at SSRs, which tend to be easily controllable with logic level outputs on a microcontroller.
Ask HN: Should I hire someone to do a code review?
Hi guys - I have no programming experience and hired an outsourcing company to create an iPhone app MVP for my idea. The first iteration looks good (and works), but before I give them money to do more work , I'd like to get a 3rd party opinion on the code quality.

The easiest way for me would be to hire a freelance developer to perform code review and provide me a honest assessment of what lies under the hood. Few questions:

1) Is this a good approach, or are there better ones?
2) What type of costs should I expect? Hourly, Fixed, etc.
3) As this reviewer will be remote, what steps can I take to protect IP, lines of code from being used for their own purposes, etc.

Thanks much
NC