skysight-inc/HackerNews huggingface dataset:
Took a few notes when reading the paper[1], expanded some acronyms as well. Definitely a nice result, and an interesting paper.

* Steve Rosenberg's a respected expert in the field

* Adoptive T cell therapy (ACT) of TIL (tumor-infiltrating lymphocytes) T cells specific for a (common) KRAS mutation (G12D)

* Culture/expand TILs, use tandem-minigenes to narrow down most reactive (to in silico ID mutations) TILs, then use synthetic peptides on the mutations encoded in the TMG that elicits largest response to find which epitopes in particular were being reacted to.

* 6 tumors eradicated, 7th shrunk but recurred (had to be resected, patient has no disease 4 months later); 7th had lost the HLA-C allele that the TCRs were specific to

* The supplementary materials/methods were pretty interesting (very technical)

[1] T-Cell Transfer Therapy Targeting Mutant KRAS in Cancer http://www.nejm.org/doi/full/10.1056/NEJMoa1609279
Reason I'm not getting into web development.
Just when you thought you've finally grasped LaTeX...
While I haven't used it with something as rarely used as Decimal, I almost always alias numpy and tensorflow to np and tf respectively. I find it cleans up the code drastically.
I never understood what people find funny in Big bang theory show. Can you still laugh at the jokes if there is no laugh track https://www.youtube.com/watch?v=AY0Zkthn8Og ? :) I like IT crowd much better.
Help me understand why you believe Matzo isn't a culinary foam. Foams aren't created solely by leavening --- or rather, all breads are intrinsically leavened somewhat by consisting of large amounts of water and being cooked, which converts bound-up water into steam that leaves bubbles behind as it evacuates the product.

Pancakes are quickbreads!
Could you elaborate? I hear that a lot but I suspect it only comes from people who don't do a lot of web development.
There's actually a useBuiltins option to remove the _extends helper if you want to use that.

https://babeljs.io/docs/plugins/transform-object-rest-spread...

Might be cool in combination with preset-env
The tools and results are now freely available to the masses. But talent isn't democratized.
Many of the ideas people have brought up are mentioned and debunked for reasonable reasons in the article. The culture of TL;DR lives.
This is one of the saddest and most orwellian aspects of today's marketing. Even if you run a tight ship, your friends are bombarded with just as much force to give up not just their information, but yours as well, undermining your efforts.
I find this more interesting than flying to Mars. Pretty cool.
I have no solid data on that and I am not a mental health practitioner in any sense.

But to my mind, no. The problems of a healthy mind in an unhealthy environment are easy to solve: change the environment and the problem goes away. On the other hand, problems such as my depression get only temporary relief from changing the environment; the only long term relief has been drug treatment.
one of my very first jobs we had products for monitoring underground petrol tanks and petrol (gas, even though it's not a gas ;-) ) pumps. All written in forth, while a bit obscure, actually was quite cool.

as an aside, The guy who was primarily responsible for that now has a FRP library ( http://sodium.nz/ ) and written a book on FRP using petrol pumps as an example
Has GitHub improved reviews since launch? I tried the review feature at launch and found it to be a severe regression from plain PR inline comments, because the review comments weren't hidden when the code they referenced changed, so I had to manually check each review comment to see whether or not it was addressed by a follow-on commit. I emailed their support asking if I was using the review feature wrong, and they said No, I was using it correctly, and it was a known weakness in the feature that they were tracking.

Review requests are useless until GitHub makes the reviews themselves useful.
Filezilla? Cyberduck? FTPFS? The FTP functionality that's built into Finder (or at least, it was the last time I used FTP - this was some time ago)?

There's no shortage of clients. Personally, I think you shouldn't use FTP at all, but you do you.
I'm still surprised that so few people know about www.spamgourmet.com it's been around for 15+ years and offers the exact feature you're talking about. You don't even have to create the alias, it will be created on first use.
I ran it at $job-1. It was fantastic once setup. We never had any issues with it and it autoscaled wonderfully.

The devs never had any issues of needing ops to add libraries/modules to servers. They just built them in their containers on dev and if it worked there the same Dockerfile was pushed to prod.
> There's a concept of strength (required, strong, medium, weak) which allows you to define which rules should be dropped in case of conflicts. [...] That said, I had to build a dedicated tool to show me which rules where overridden or why otherwise it was very hard to understand what happened when the layout didn't work as I expected.

That sounds like "strength" was probably the wrong approach. Why not require the developer to simply resolve conflicts? Your set of inequalities are a basic type system and you tried to resolve your type errors by layering some secondary weird "overriding" type system over top. Better to just resolve the errors from the get-go, and when it compiles, you know it will run correctly.

> The most annoying instance is line breaking. You cannot encode how lines are going to break as a set of linear inequations.

Is this discussed anywhere in more detail? It doesn't sound right to me, unless I'm misunderstanding what you mean here.
"We don't talk about CR1". ;-)
Most cakes are quickbreads. We don't eat them the way we eat other breads (as a utilitarian cuisine staple), just like we no longer really eat biscuits as a staple bread --- but for a long time, biscuits were the staple bread for lots of people.

As you can see, my definition of bread is functional --- it's about how the bread is constructed and how it behaves as a final product. But there are other valid definitions of bread that capture things like the setting in which they're consumed --- maybe the default for things consumed in a pastry setting shouldn't be "bread", even when the product is a culinary foam made of a dough (but then you run into trouble with sweetened breads eaten as desserts!).

I'm fine with those definitions too, but would note that they rule out none of these indian breads. I'm pushing the functional definition because the parent commenter tried to rule out dosas based on a functional definition, and that functional definition was incorrect.

(There are obviously exceptions for "cakes" that are really set custards and things like that. But birthday cake isn't such an exception.)
Or maybe they never really had any intention of wiping out humanity and that is their way to preserve humans. The same way we preserve animals in zoos. Maybe this is just a human sanctuary along with zion.

Humans are just too stupid/arrogant to believe it.

If we get a little bit too annoying or dangerous they just cull us the same way we cull foxes or bears attacking livestock. We are never really a threat to them. Especially if you consider that they are a million steps ahead of us given their intelligence.

A single AI being is more intelligent than the entire human race that has ever lived; there are millions of independent AI's in the machine society. Once you look at it this way it is laughable to think that humans have even a tiny chance against an entire society of AI entities.

We think we pose a threat the same way a bear thinks it posses a threat against an armed human. The bear may get lucky against a few humans but against the entire human species it has zero chance.

Also, given that the mind of an AI is just software they are virtually immortal. Every time humans "kill" a machine it is just a piece of hardware that is being destroyed. The mind is still intact. So yeah, as soon as a sentient AI comes into being, the fight will be over before it starts. We think we are intelligent but just look at how long it takes us to study for a career. An AI will be able to learn all of human knowledge in a virtual instant. We are doomed!

If you follow this line of thinking you can fill a lot of the plot holes in the movies.

The agents are just zookeepers.
Title seems a bit off, per caveat below...why not use the original title, "WinFsp Performance Testing" (?)

"The comparison to NTFS is very important to establish a baseline. It is also very misleading because NTFS is a disk file system and MEMFS (either the WinFsp or Dokany variants) is an in memory file system. The tests will show that MEMFS is faster than NTFS. This should not be taken to mean that we are trying to make the (obvious) claim that an in memory file system is faster than a disk file system, but to show that the approach of writing a file system in user mode is a valid proposition and can be efficient."
Yes, outdated comments are hidden again.
What will the effect on battery life be?
I haven't even checked the site out (yet, hear me out), but this is one of the most positive reactions I've seen on HN. So congrats on that already.
Wouldn't it be an unfortunate accident of history if the same frequency works for humans and having a mains frequency of 40 Hz would have automatically prevented Alzheimer's through most people's daily exposure to CRT TV screens and light bulbs.
FOSS DOS for 21st Century Hardware
A pure Python implementation of lxml would be exceedingly slow.
Yes this is very useful for this. Thank you for the link!
Medium SKD for Elixir
K-means is based on some quite wild assumptions - your data follows a specific case of the Gaussian distribution. Plus side is that the algorithm is relatively easy to understand and implement so it is a good starting point into clustering.

When you got this, then next step is probably to consider if the centroid is really a good representation of the distribution of your data. If you still believe that your data is about to follow some form of Gaussian distribution then K-means can be levelled up with the EM algorithm.

More over, if you are faced with some crazy multidimensional data then it may be fair first try to reduce the dimensionality of the data with the PCA or t-SNE algorithm or with combination of both. Or perhaps use autoencoders.
It it is one of those interesting metrics, or one I came across researching the Cortex-M which is that at modern process node geometries the CPU part of a Cortex-M chip (not including all of the on chip peripherals, RAM, and Flash) easily fits inside the bond pad of an 8080A. As the 8080A had 40 pins that is 40 Cortex-M CPUs in silicon that Intel "threw away" by depositing a square of gold on the silicon.

But in terms of documentation that is related directly to the transistors, it would be interesting to evaluate number of lines of VHDL to the number of inferred transistors. I know you get a report after you have finished place and route on your typical work flow but has anyone rolled that up to "2.5 lines of VHDL per 100 transistors" or something?
Thanks! I look forward to taking reviews for another test drive soon.
I would say that roughly 25% of the documentation applies to ancient modes of operation like real mode and protected mode. Unless you REALLY need to know the fine details of these modes you can skip right to the long mode stuff.
Having seen much but not all of it, I think it's top-notch TV drama with excellent writing and acting both.

But I think the computers, however well realized, are just the backdrop. It's really about questions of identity, morality, and sanity.

Much of the hacking is hacking the self, often through drugs and/or psychological manipulation.
Probably a textbook.
I get doing something like this as a learning project. All I'm saying is that we should actively be trying to kill off FTP for good. There are superior protocols (and workflows for that matter). I will concede that it looks like a fantastic FTP client, but would you be excited about a dial up modem controller (no matter how nice it looked)? Or a really fancy cassette tape player? It's an interesting thought experiment to see what those technologies might look like if they were brought to market today, but it's very strange to want people to actually use them in my opinion.
I alwayse took it as a crass metaphor for human labor
>In the tiny group of gamblers who have become top players at both blackjack and poker, there is only one woman.In her own words, Cat Hulbert describes how she got rich beating male opponents - and the casinos - and explains why in her view women are innately better at poker than men.

Yeah... about that. If there's really only one woman "top player", I don't see much support for her view.

I played poker for decades, and one thing I learned was it's a lot easier to lie to yourself than the other people at the table.
A sizeable contingent of Hacker News readers love Ted Chiang's stuff so it's not uncommon for links to his stories to surface on HN from time to time, but I think you're correct that Arrival's success has revived interest in his older stuff.
Which trivial app is 60MB? Most apps I use are 1-10MB. The games are, of course, much larger.
51% of Wikipedians believe that the word "Pita" is literally derived from West Asian words (in several languages) for (wait for it) "bread".

Pita is obviously bread. Even your definition, which requires "baking in an oven", covers pita. If pita isn't bread, neither is naan --- at which point we've reached a pretty silly place of defining one of the world's most popular breads as "not bread".
Show HN: Simple virtual machine, assembler, and C compiler
Usually $app actually requires access to internet for stuff you are unaware of.
Interesting. I have used CAS extensively and was involved in building SAML support for a commercial app at one time. I didn't understand the post-binding thing really at all--CAS mostly uses the back channel method.

My experience with SAML was that, not only was it a bear to get set up, the second client who wanted to use it was using a different SAML implementation and found things weren't as standardized as we had assumed. Both implementations supplied a principal, only one supplied an email address by default. I think it got sorted out after I left.

I don't love CAS a lot, but it is a lot more turnkey than SAML.

We're investigating JWT now, but I have a feeling it will turn out to be an implementation detail within a larger solution that we haven't even begun to conceive.

I've also implemented shitty poor-man's federation on top of CAS. My recommendation there would be: don't do it. If you need federation CAS really can't help you, don't hack on it.

The other thing I've learned is that none of these things is going to help you with authentication at all, and that tends to be something that isn't well thought-out before implementation time comes.
And on the body?
Dev kits seem to already be available: http://www.digikey.com/short/3594m8
I've never played DCSS, but after a few nethack ascensions I've found its "chores" (getting the wand, etc) interfere with actually enjoying the parts of the genre I like most: resource management in an unknown world. I suspect DCSS will be a similar experience.

For those that feel similarly, I heartily recommend giving brogue[0] a try. It's beautiful, balances many strategies without giving dominance to any (dwarven valkyrie, anyone?) and drops the "schlepping" associated with nethack and related titles.

[0]: https://sites.google.com/site/broguegame/
An Open Source Toolkit for Lightweight Multilingual Entity Linking
Look at the number of binding/UI frameworks, look at the package managers, look at the number of unit test libraries, look at the number of build tools. Many get reinvented in a bubble when there are plenty of options already.

Now half (maybe more) of the libraries are being written in languages that aren't javascript so now there are multiple competing ecosystems on top of javascript.

And then you have things like angular creating churn within the framework.
LinkedIn currently says 701 people work there. It's a fairly large operation.
One problem for open source HW watch is that a lot of other folks will just use their factories in ShenZhen to clone the HW sell it for cheap without any R&D and marketing.

Similar to how OrangePI leverage Raspberry Pi situations.

It becomes race to the bottom ($5-10 pi zero) and no one can make $ in the market in both short and long term.

There seem to be a lot of sub $20 watch base on following links - not sure how good/bad are they.

https://www.alibaba.com/trade/search?fsb=y&IndexArea=product...
https://cs.uwaterloo.ca/journals/JIS/VOL7/Sloane/sloane15.pd...

I get that lin alg maybe isn't your picture of elegance, but you can't say that proof is laborious or esoteric. Any intro-level LA course is enough to grok it.
Maybe it was the same (overused) restaurant wordpress theme that has nothing to do with Bootstrap? Sites looking similar was an 'issue' well before Bootstrap.
@insulinrocks you appear to be shadowbanned
We got brand new 25 year old codec now! PATENTED and owned by Qualcomm

https://en.wikipedia.org/wiki/AptX
Nginx, Django/Python and MySQL. Nothing fancy.

No company actually. Just side projects. The largest being searchcode.com

Feel free to email me if you want further details on either. Details in my profile.
> in 0-60 time.

Ah yes, I should've been more specific and said acceleration instead of speed.

This is what I was talking about when I said there are a lot of variables to measure performance lol.
Musk: “There’s a Pretty Good Chance We’ll End Up with Universal Basic Income”
I hope that my post can help you then! It seems as if with the custom slot type, I was able to create my own slot type for each of the things I needed. Then I gave it some sample inputs for that type and I tried making it general but covering different types of inputs (ones with numbers, symbols etc). Here is a link to my IntentSchema.json file to see how I made the intents: https://github.com/acucciniello/alexa-open-doc/blob/master/s.... Here is a link to folder containing the slot type definition files: https://github.com/acucciniello/alexa-open-doc/tree/master/s....
Yeah, I cottoned to that eventually - it's short(er)-hand for Perl 5's qw() construct. I guess Set is a method (coercer!) of...lists? List-shaped things? Sets seem list-shaped, although indexing doesn't work by any syntax I could find, and certainly not by any that an @ sigil should suggest. Can I call Set on a set? Does it do something weird if I do? And if I'm going to deal with this kind of high weirdness, why not just bite the bullet and go with Haskell or even Urbit? This just feels like it's trying to out-Ruby Ruby, and Ruby is Ruby enough already.

The OP had some snark to offer on the subject of "Texas" operators, and the documentation lists them by their Unicode glyphs. That they work I get. But I think it's reasonable to gather a sense of second-class citizenship from their presentation.
They might not have traces of the actual event. Rather, there will be mentions of it in articles and leftovers from social media. Pictures and stories of it.

It will likely be written in some weird version of English, and they won't really know for certain if they have the terms correct.

And this is just going by what we have now.

And then some occult kids somewhere will think it is pretty cool, and make up a story to go with it. And the cycle will continue. (or not, but it seems like a good ending).
I have some experience with this since I went straight from high school to working in San Francisco. I don't know about the best city for someone without degree, but the best city for tech by far is San Francisco. To give you an idea of how dense the tech scene is in SF, the headquarters of Uber, Square, and Twitter, are all within two blocks of each other. There are hundreds, if not thousands, of other tech companies just a few blocks further from there.

As for companies, I have found it much easier to interview at larger companies than smaller ones. When I applied to three larger companies (Uber, Google, Dropbox) all of who were interviewed me and eventually made me an offer. I also applied to six smaller companies, of which four rejected me without interview, and the remaining two wound up making me offers.

Since I was unsure whether I would be able to get a job or not, I deferred from college for a year, so I could always go back if I couldn't find a job. Depending on your situation, this may or may not apply to you.
Really good job! It turned out better than most templates.
All I can think of is the Archer pirate virus

https://www.youtube.com/watch?v=dJnklyxbcL8
Given that NIST now explicitly says you shouldn't use SMS for 2FA, I'm not sure why we're even trying to compare U2F to SMS OTP. It's just not a useful comparison at all. Any company that is even considering supporting U2F should already be offering non-SMS-based OTP anyway.
I don't think there will be a complete loss of records, just incomplete ones. The writing will evolve, so it'll be hard to understand.
> 6to5 did exactly that: easily turn ES6 code into ES5 codee
Wow, thank you!
Honestly, I don't understand half of it right now, but hey - now I've got something new to learn.

Really thank you very much :)
I have a Yubikey Nano in each of my computers, that are registered with everything that supports U2F (currently only Google and Github). I also have a Yubikey Neo that's on my keychain. Between all of these, I never have any U2F problems.

Except my iPhone, which can't get OTP codes over NFC like Android phones can. So actually I have Google Authenticator for TOTP codes.
>Hacker Vision, which lets you see people and objects through walls //

Mapping/tracking with wifi signals [from special devices IIRC]? http://www.theverge.com/2015/10/28/9625636/rf-capture-mit-wi...
/r/itsaunixsystem
I think editing critical Reddit comments as part of a prank or maybe as a jokey form of retribution is an extremely ill-advised and boneheaded move. I don't know if it was abusive and it was hardly covert, but it was definitely not cool. I doubt Spez will make that mistake again.

But did it tell us anything new? Are we surprised that Reddit admins have the technical ability to edit records in their own database? (As do the admins of other social media sites...)
It's Not Cold Fusion but It's Something
Could anyone point to the main (La)TeX files? I seem to find only documentation such as [1].

[1] https://gitlab.brokenpipe.de/stettberger/avremu/blob/f634322...
It's common in the West to equate "bread" with things that are savoury, but a visit to your local Asian bakery will quickly demolish that notion.

So, yes, a birthday cake is a special type of highly decorated, sweet "bread". Or you can take a leaf from the Swedish/Finnish book and have a savoury cake:

https://en.wikipedia.org/wiki/Sm%C3%B6rg%C3%A5st%C3%A5rta
>>Now, any biologists worth their salt would cringe at many scenes [in Jurassic World].

Jurassic World is science-fiction, which makes it a hell of a lot easier for subject matter experts in the audience to suspend their disbelief when it comes to the technical parts. Furthermore, said technical parts take up maybe a few minutes of the film at most, keeping the need for the suspension of disbelief to a minimum.

Mr. Robot, on the other hand, is drama, and the main character is a hacker who hangs out with other hackers. In order for it to be viable as a show, it needs to be technically accurate.
I just started using Resend.io, which has all 3 of these features in a simple package. The founder has been responsive and the product keeps improving. I was looking for a simple Intercom replacement, Intercom has become very complex.
I am not sure if building static HTML pages represents the bulk of what web development is about.

(Disclaimer: I am a "web developer")
This is one of my favorite short stories and such a fantastic metaphor for climate change.