skysight-inc/HackerNews huggingface dataset:
Good read. Been through exactly this with my father. Obviously no causality, he could have started dementia without the treatment, but gives some backstory to what my family went through.

One important point is that the hormones probably add more life than they take. You don't start on hormones AFAIK before they figure they can't cure you anymore. It's then about prolonging life. First to admit that dementia is horrible as well, but for most patients a risk worth taking.

Further reading:

-99% survival in 10 yrs regardless of initial treatment in the dataset (in article)?

-It seems there is a subset where ADT is first treatment. That is at odds with what our oncologist told us iirc. ADT prolonges, but does not cure. Makes some sense to prescribe ADT if alternatives are too heavy, but that is at odds with the 99% 10 yr survival.

As an actuary: only children have 99% 10 yr survival (guesstimate).

Went to the article. Not paywalled (nice). They include common logic comparisons and stuff. Love the approach to text processing. But no basic data tables?

Death should be really common when studying 60-70-80 yr olds. Gleason score mostly 6 or higher. That gives you a 30%+ baseline of dying (ballpark, Google).

Next thought: data gathering conditional on survival. Only if there is a follow-up, you can be included. That still makes sense re the study (relative chance of dementia), but makes interpretation harder. It's an analysis in one branche of the probability tree. ADT might make your dementia chance 100% if nothing else kills you first.

Still a nice study. Just don't think of this if you've just been diagnosed. Draw the entire tree. You need to survive first.
Thanks for the clarifications!

The Flynn auto-heal - does that monitor infrastructure (ie at the VM level) or is that process auto-healing?
You're neglecting other steps, cutting, button holes, ironing etc, this is also not a pair of jeans, handbang or other more complex garments.
Is there a guide on how to make Unity or Gnome look like that? I haven't used either in quite a while.
That was also my first question. I looked at the original paper [1], the medication names they used to identify individuals on androgen deprivation therapy are listed in the 'eAppendix':

Leuprolide, goserelin, triptorelin, histrelin, Degarelix, flutamide, bicalutamide, nilutamide, Enzalutamide, Cyproterone acetate, Lupron, Zoladex, Trelstar, Vantas, Firmagon, Eulexin, Casodex, Nilandron, Xtandi, Nizoral, Androcur, Eligard, Cyprostat, Anandron, Flutamin, Cytomid, Cosudex, Calutide, Kalumid

So relax, finasteride does not seem to be on the list.

[1] http://jamanetwork.com/journals/jamaoncology/fullarticle/256... (probably paywalled)
Not in this case, Flynn runs on Ubuntu 14.04. I think the reboot was a DigitalOcean droplet's host being restarted at the time though I can't be sure.
3 Formas de Aumentar Rapidamente O Tráfego Do Seu Site
ADT is Androgen deprivation therapy, a superset of using anti-androgens.

And Finasteride is only kinda an anti-androgen itself. It blocks conversion of some Testosterone to DHT, which is another androgen which is more potent WRT hair loss, body hair growth, and prostate problems, but I believe less potent WRT other effects of androgens.
> It's fast, unobtrusive

I'm still using an $ECONFDIR that was initially created in ~1997 for exactly that reason. Everything else is either missing features (windowmaker) or slow (everything else).
I think I like the recent work on pulsed fission-fusion better. Basically you have a normal z-pinch fusion system but surround the fusing hydrogen with U238. It absorbs the fast neutrons from the fusion, fissions, and creates more heat driving the fusion. There's some radioactive waste flying out the nozzle but if you're already in space that's not a huge problem.

On the upside, people aren't going to get nervous about nuclear weapons in space since you can't trigger the fuel pellets outside the engine. And you don't need a massive pusher plate, you just direct the charged plasma with magnetic fields. And that means you can wait to turn this on until you're in orbit and avoid creating any fallout on Earth.

https://www.nasa.gov/content/pulsed-fission-fusion-puff-prop...
If you want a DE that is almost as lightweight as MATE, but has a more modern feel I would recommend Cinnamon[1]. There is also a Fedora spin if you prefer that to Debian based distros.

I've been using Cinnamon as my DE for about a year now and I absolutely love it. The biggest thing that made me switch is the fact that it just works. GNOME would shit the bed every time I docked my computer into its docking station, Cinnamon handles it just fine and can even remember my monitor configurations.

[1]:https://en.wikipedia.org/wiki/Cinnamon_(software)
Gnome (or is it Unity?) I have in my Fedora looks nice. Visually much beter than KDE. But it's like 50% empty space. Which is really, really bad. These screenshots look fine to me at the first glance.
Are desserts that big a part of the bottom line? Surely as long you order drinks and a few courses I doubt the restaurant cares too much one way or the other if you then order desert.

the generally agreed-upon admonition , "Don't bother ordering dessert there," is a devastatingly horrible outcome.

Is it? I would say that about many of my favorite places to eat.
Mods should remove this obvious troll.
It would be helpful for the README to explain the reasons you might prefer this over a traditional keyserver.
Finasteride doesn't affect testosterone, but DHT, so maybe not?

(It affects conversion of Test. in DHT)
ElixirWeekly Issue #14: ElixirStatus Update, How to Iterate and New Workshops
Can you (or somebody) explain this? It sounds interesting but I don't understand exactly what that sentence means.
India's startup bubble has already burst
Say one of the currently powerful countries establish a research station on the other side of the Atlantic, and it becomes self-sustaining at some point, from say mining and wood harvesting and growing food on fields, powered by horsepower.
What if that colony decides to become politically independent?
Would any of the nations back on this side of Atlantic be able to project force on the far side of Atlantic? Won't it be very easy for the Americans to just shoot down any approaching ships?
I've used KDE when I used Linux as my main OS (I've since moved it into VM and use mostly command line). Not because it looked nice (it didn't), but the customization options were far ahead of Gnome (not to mention Gnome2 felt like Windows 95).

And to this day Gnome has the worst "Settings Panel" I've seen. Windows 95 included. It's just.. horrible.
These students are funded anyway and decided to add a publication on an area they love.

They included their funding bodies because it is required by their funding agreement.
I suspect that AliExpress helps sellers manipulate ratings, else the sellers wouldn't turn a deaf ear to any queries.

Moreover, I'm not even sure how does the rating system on AliExpress work. I wasn't even given an option to rate the seller. The official support is terrible; they'd act as if they're very concerned but they wouldn't do anything even if the seller doesn't respond to any of your messages.
I just want to use whatever tools we will be using in 5 years. While the underlying technologies of css, html, and javascript have gotten cleaner, powerful, and more cross-compatible, everything that sits on top seems to have gotten bloated.
The team can set up a linting rule to flag any use of superglobals and block committing them.
I remember hearing a story about a Russian tzar who was drawing plans for a railroad. He was trying to draw a straight line by holding a ruler down with his thumb. The writing utensil he used hit his thumb and went around it, creating a bump. The railroad was built perfectly straight except that one bump in the middle of nowhere.

Edit: apparently this was a myth, http://bigthink.com/strange-maps/580-the-legend-of-the-tsars...

It is strange that all the crap I heard as a kid and took for granted for most of my life can suddenly pop into my head and now be verified because of the internet.
This is why I first build my projects in PHP and only move them to ASP when they succeed!
No current plans, but feel free to request it in a GitHub issue. We consider the number of votes on GitHub when adding to the roadmap.
U.S. Satisfaction Remains Low Leading Up to Election
I miss the BattleToads threads, especially when they would record their calls to the Pawn Stars and GameStop stores. Or just visiting 4chanarchive to watch drama unfold in some previously massive thread. There just isn't anything like it on the Internet still, as far as I'm aware. Unless you enjoy a 'LIK DIS IF YOU CRY EVERTIM' Facebook post.
Bucky! It has been many years since I saw that name. Made me smile, it is where all my real programming started. I would love to send him something out of gratification.
How Call Centers Can Make More Money with CRM and Cloud Hosting
That's at the process level only currently.
Accused UK 'flash crash' trader to be extradited to U.S
YouTube is huge. If you just search the videos from the last week and sort by the number of views, there will be lots of stuff from the popular YouTubers that you don't care for, like makeup tutorials, reactions, some 15 year old ranting incoherently.

YouTube main page has recommended videos, which, if you use YouTube regularly, it not bad at all - it learns from your voting and viewing habits.
Which of the following seems more likely?

A recruiter who was already giving the guy the wrong interview, and whose job revolves essentially around HR and sales, made mistakes in asking a series of technical questions.

An expert with decades of relevant technical experience misunderstands and confuses basic networking and system topics.
Besides memes and internet jokes, what are examples of high quality content created (or originating) from the "chan" culture?
> "...By default, registration of new users is disabled."

It's good to know that it can be disabled, but I'm mostly concerned with attack surface, minimalism/hackability and not getting caught on an upgrade treadmill. At the moment my personal Web site is static, the Web UI to my git repos is static and read-only, pushing to those repos is done via SSH, I accept patches by email, etc.

I'm hesistant to run anything dynamic at all, let alone something more complex than I need (e.g. a Web frontend) with the capability to perform destructive actions which I don't need (even if they're marked 'disabled').

It would be nice to have an Internet-facing server which only deals with untrusted data, accumulates incoming updates to a file (e.g. sqlite), pushes out posts from a queue (e.g. a directory) and serves the necessary public info when requested, maybe using static files for stuff like my profile. I can then read and write those files over SSH, maybe transforming them into some easy to consume format like maildir.

Of course, the first rule of security is don't write it yourself, but this is beginning to sound like a nice weekend project :)
Granted it's difficult to remember the type of the casual e-mail address or of a list of integers. In Haskell, where there are a thousand ways of encoding the most trivial things, that is.

In my own practice, most transformations don't involve relations over more than 5 variables with mostly obvious types. Yes, this is hard to use:

https://tronche.com/gui/x/xlib/window/XCreateWindow.html

But then 1) there might be nicer ways to design an API
and 2) at these few places the implementor of the API can just insert value assertions.
Ah, I still remember complaing on the mailing list that this new "Kool Desktop Environment" (yes, that was its name) had no proper HIG and it's probably better if they get some style guides ready before starting up...

The heady days of early Linux GUIs. When Tk was king and nobody thought that somebody would do something like Xt again...
I don't think KDE looks particularly good, but it works for me (usability wise, and it's not ugly enough to constantly barf - some details look quite nice, but the big picture kidna doesn't).

Gtk on the other hand I can't really handle. Both Gnome and Unity look not that different on a basic level, but aren't nearly as usable to me as KDE (personally I find many design features in both of them also more ugly).

Other DEs just look worse.

I recently tried Qubes (3.2) on a laptop and was amazed how ugly it is. There are literally dozens of window decorations in Xfce, and all of them look like shit. Practically nothing changed there since half a decade ago when I last used Xfce. Even some obvious graphical bugs persisted!

Color scheme support is also universally bad in Linux land (or maybe generally? Windows is poor here, too. OSX I don't know). Wrong combinations of colors (dark grey text on slightly darker background? A pleasure!), apps just not using the color scheme, inverted colors in some apps/places etc.

Some "DEs" don't try and just admit design failure. Eg. i3 which I'm using on some laptops since a couple years. It doesn't even have any design to speak of. I only use it, because it works extraordinarily well for me.

</rant>

Don't even get me started on font rendering. I know it's an utterly difficult topic, and that a lot of work went into it to improve it (and some of this is fairly recent). Still, the font rendering quality is often still rather underwhelming. And in past times, or on older or misconfigured distros (F23 on Qubes for example) the quality is just heinous.
LinuxJournal Self Driving Vehicles (1999)
Yeah, check out this blog post about how to deploy Phoenix: http://nsomar.com/how-to-use-flynn-to-deploy-a-phenix-app/

Distributed communication should work fine, feel free to ping us on IRC or GitHub if you run into any trouble or have any questions!
Cristiano Ronaldo Wins Champions League Best Player Award
Compilers spend a lot of time with hashtables, which exist on the heap. Rust isn't some magical language that makes the heap some unnecessary entity. One still has objects whose lifetime do not fit the stack model or whose size is dynamic

Their comment went on to claim that given their hypothesis, allocation optimization shouldn't be impactful. Yet this post demonstrates otherwise, perhaps showing that therefore their hypothesis is false (if a then b, b is false, therefore a is false)

One of the post's optimizations was to use Cow<str> over String tho, which is an example of reducing allocations with borrows

Additionally it's oft mentioned that a weak point in Rust's compile time is LLVM. This has to do with various things, some of which are Rust's fault (it could generate less IR), but it points out that there's a lot of time being spent in C++ code. LLVM's great, but it's guidelines essentially suggest 'if you want to make llvm play nice, generate IR like clang'
I like the Java Brains for Java technologies.

https://www.youtube.com/user/koushks
Ahhhhh, PHP.

Never again.

Life's too short to waste on that junk.
Reducing Oracle Licensing Cost on Nutanix
Half Obsessions – an enewsletter that focuses on one thing, for one week
Native Compilation – Why JIT When You Can CodeGen? (.NET)
Mozilla is financing the open competitor to Facebooks free-internet
For Java technologies like Spring, Jax-RS & etc.,
https://www.youtube.com/user/koushks
Considering that one of internet's strength is the democratization of content creation, low-effort anyone-could-do-it contents are inherently high quality.
Probably someone had a photo of a possible target but didn't know the location so they crowdsourced that to 4chan.
Unless it ends up in a wrong bank in the other system in US, who do not have SWIFT codes. If it's gone then, because back routing info can and has been lost.
Ask HN: Would you like to see fact checking on “Facebook trending”
I was hoping for support for this:

https://www.facebook.com/help/community/question/?id=10209666887980502&added&rdrhc
Was it not the Mayans who predicted some kind of cataclysm?

But yeah, I agree it's ridiculous how the Clinton campaign took the bait and now apparently a cartoon frog is a "hate symbol".
the counterculture was very vocal and very interesting phenomenon, did a majority of the young people of the day subscribe to it? I don't think so. Did they really change things in a larger sense? Don't know, might be 'too early to say'.
Less aggressively, you may also be inheriting someone else's design.
Yeah, I'm sorry but I dispute it is easier to use than plain C.
The Untold Story of How Salesforce.com Became a Billion-Dollar Company
Posts linking their replies in the header has been a feature for a very, very long time. This doesn't have the negative impact you think it does. It's not a post rating system, and only trolls and candyasses pay attention to the number of replies on your post.

There isn't any kind of long-term karma game like on other sites. 4chan is still content-heavy and shit posts are still looked down upon by the larger community. It may not seem that way, but the stupidest people are often the loudest.
Why not, especially when we're lumping together everything from baking cupcakes to preparing a tiered wedding cake?
Re. development of KDE - I don't really get the hate here. I used KDE 3, 4 and KF5 currently. Still don't get it.
International wire transfers just do not work for small amounts. Even in case of EU internal you can get hit with equivalent of 3-5 € each.

Going to US? Better bring $30.
Your dashboard seems like an interesting approach for taking the best of both worlds!

learnapollo seems awesome too! I think that Apollo would benefit from this kind of documentation. You should definitely come and send a link on the Apollo's slack!

In general Graphcool is a great idea if you want to start fast with GraphQL (with any client).
Yeah, maybe not the right forum to cover all of your questions in detail but here are a few bullet points (note: I cust came across bitwarden, too, so this is just from what I gathered from the website and the little time I've spent playing around with it):

Similarities:

- Open Source

- Cross Platform

- It appears to be possible to host your own server

Differences:

- As pointed out somewhere else, Bitwarden is very limited in what you can store. It seems to be primarily for storing website logins and does not offer any customisation options for storing other kinds of data. Padlock is much more flexible in that it allows you to add any number of fields to any given record.

- Apart from the mobile apps, the primary way to access your data seems to be the website served over https. This is a terrible idea for a ton of reasons and I could spent all day going into all of them but lets just say that there is simply no way to handle your data in a secure and private manner this way (either you have to do crypto client-side which is inherently insecure for a website served over the net or you have to do it server-side which means you have to send your master password to the server). By contrast the Padlock app, although based on web technologies (it's built with Polymer), is only available as a packaged (and code signed!) app for all platforms. This means that you can safely do client-side encryption without having to worry about the integrity of the source code. Padlock Cloud on the other hand is built on the principle of Zero-Knowledge, meaning no unencrypted sensitive data is ever sent to the server.

I could go on forever, but this will have to do for now. If you have any specific questions, let me know!
Yes, the mix of Tk, Lesstif, Xaw... Each of them ugly, and no consistency between them.

KDE was suddenly a modern UI on Linux!
Seeing "LaTeX" (lay-tech) and "arXiv" together in your sentence made me finally realize that arXiv is pronounced "archive". I've been reading it as "arx-iv" for years.
Because unemployment improved for everybody, but it improved for a significantly smaller percentage of blacks that it did for the population as a whole.
The Video game Daily
Every board in 4chan has it's amount of shitposting. One thing you start developing, as a user, is an semiconscious filter and ways to process the information.

A *chan site has many layers a user must go through to finally fing a decent discussion (or the epic lulz). You have an outdated confusing UI, the sheer amount of useless content, the lingo and the highly offensive content.

After you learn to process and filter all that, you start finding the really good stuff. Or, as I like to say, "Gold floats on shit. You just have to be brave and reach it"
At work, I am stuck doin maintenance on an in-house application our accounting department uses, which is written in Delphi. It's small (~10k lines of code), but it compiles so fast I sometimes wonder if I clicked the wrong button / hit the wrong key.
Nothing in particular. I was just looking for a bit of a change and to gain more rounded experience. Being pigeonholed into one specific area (3D/CAD/CAM C++ development) for many years isn't that great for future career prospects, especially in a market where most mainstream job titles seem to be split into a front-end or a back-end development category, and my experience doesn't seem to put me in either...
Are Black Hole Starships Possible (2009) [pdf]
How to Use Content Marketing to Attract Customers
This is the only Lego yellow submarine I'll ever be able to think of[1].

I wish Lego would do more rereleases of some of their back-catalog stuff. I think they'd make a killing, given prices on secondary markets for even used and abused sets. Especially with how quickly they rotate themes and how short a period of time sets remain in production these days.

[1] http://brickset.com/sets/6175-1/Crystal-Explorer-Sub
OpenCAPI consortium launches
>Posts linking their replies in the header has been a feature for a very, very long time.

Before, that was add-on/userscript feature. Since moot adopted them into 4chan's codebase, everyone has it.

>only trolls and candyasses pay attention to the number of replies on your post

Exactly. This feature encourages and rewards trolls and people who fish for replies.

>There isn't any kind of long-term karma game like on other sites. 4chan is still content-heavy and shit posts are still looked down upon by the larger community.

The dynamic of the discussion changes though. Even a slight nod matters in a long run considering that 4chan's culture evolves in a very rapid pace, thanks to its ephemerality and anonymity.

>

Come on.
I Ii

II I_
>Does a more expensive pastry chef produce more expensive pastry? Or can a more experienced chef produce higher volume also? If the cost of the pastry increases with the cost of the chef, then it's entirely reasonable that there is a lower demand for more expensive pastry and therefore a lower demand for more expensive pastry chefs.

Yeah, god forbid the actual quality of the pastry comes into play, and that the restaurant/bakery/etc takes pride in its output.
I think it would be better without the horizontal lines.
It's because people who knew him and were close to him didn't reveal much about the date of death, the exact cause or other details. Wikipedia [1] just states this:

> Ritchie was found dead on October 12, 2011, at the age of 70 at his home in Berkeley Heights, New Jersey, where he lived alone. First news of his death came from his former colleague, Rob Pike. The cause and exact time of death have not been disclosed. He had been in frail health for several years following treatment for prostate cancer and heart disease.

Even Rob Pike heard of this news and didn't have more information. [2]

[1]: https://en.wikipedia.org/wiki/Dennis_Ritchie#Death

[2]: https://plus.google.com/+RobPikeTheHuman/posts/ENuEDDYfvKP