skysight-inc/HackerNews huggingface dataset:
Given low birth rates in developed countries I'm not sure that the population explosion would sustain itself if the area was properly governed.
Double-edged sword of regulation:

some aspects of regulation protects monopolies, increases burdens on businesses trying to sell life-saving products, self-justifies bureaucracy and adds cost and delay. Other aspects of regulation prevents unsafe, scam and inferior products from endangering public safety. Both positives and negatives, to varying degrees, are in play simultaneously, given a particular product or issue. We need the FDA to not be lap-dogs of industry, not block dying cancer patients from trying almost any experimental, unapproved protocols and not taking forever to approve revolutionary therapies.

To modify James Madison's quote: "If everyone were angels, no government regulation would be needed and libertarianism would be as practical of an utopian system as communism."

It's balanced, expedient and effective regulation that is the primary duty of medical regulators.
Ther's an abysmal difference between hacking something together an manufacturing a reliable product at scale that people can bet their lives on. Everything, from R&D to the cost of lawsuits, FDA trials and regulatory frameworks makes these comparisons dumb and ridiculous.

I've been manufacturing products for thirty years. It's never simple for good products, not even a cup of coffee at Starbucks.
Uber’s terrifying “ghost drivers” are freaking out passengers in China
Amazing! ST is the only editor I considered good enough to pay for and I can see it's getting even better!
Meta: It seems really odd that this has been relegated to page two, considering that "MS and Lenovo secret agreement" headlines sat on the top page most of yesterday, largely unsubstantiated.

I could be crazy, but HN's algos seem much too aggressive about hiding articles due to flags. It often feels like the most interesting articles are to be found 2-3 spots into the second page.
The technology is old and should be priced competitively by now. To just come up with random numbers for a price doesn't make much sense. With your sandwich example - Subway sells $4 sandwiches because they have to, and they make plenty of profit. If they tried to sell the same sandwiches for $14, nobody would buy them and they would be out of business. The same level of competition does not exist with the epipen because of poor legislation and corruption within the FDA.

If significant competition existed, epipens would cost very close to $30 or however much they cost to make. There are many viable businesses operating at low margins.
You're talking about small-scale, individual solutions... ones that you'd throw at a random obese person.

He's talking about a population level crisis. "People eat too much" doesn't answer the question anymore.
Except this isn't a purely hacker-built injector. They're using an off the shelf FDA approved injector sold as suitable for diabetics including use by children and the elderly.

The hack is putting in your own needle + medicine.
That when SA started "attacking" Iran and Russia (the countries), and the US and Canadian oil industries (not the countries), by reducing oil prices.

They started drawing from their fund to continue paying for all the entitlements their citizens expect.

They calculate they can ride it out longer than the rest because of their fund. So far they are correct.
For starter, stop drinking liters of cold drink and beer every day. If you really need it, I will create an app for that.
Self awareness is key and a break to do something else like a discussion here for a while is reasonable, too.

We all might look back at this moment as the moment it all changed, we all held our heads up and made eye contact. We put away the devices. Cats slept with dogs. And dogs slept with donkeys. There was something different about the world that morning.

I'm glad I stumbled on this thread even though I sort of argued with myself today whether I should regret the time spent on this thread or not. I won the debate.
It's similar to Goto Definition (F12). It's based on parsing according to the syntax definition (which only does line by line contextual parsing) so kinda like ctags. In practice it works better than the painfully slow "smart" and often non-existent* symbol navigation in IDEs (although QtCreator is very good in this regard).

* for large projects
> is worth it if that person worth $60M can eek out even a few extra basis points in returns

[...] and no one else could/would have performed better for less than $60M.
Alright, I'll stop making new accounts (I may need to make one more, since I haven't saved the passwords for any of them). This will reduce my propensity to comment due to anxiety about the sum-is-greater-than-its-parts nature of information disclosures.
Instagram is a horrible image portfolio system. It does not offer full res downloads, has zero exif data, extremely limited desktop app. Instagram is a social media app first, and a photo app second.
Speeches were written beforehand, texts are stored in archive. This is a proven tech.

Alternatively, it was (and in justice courts, still is) to have people write down everything that was said. There are several techniques to write fast enough to catch every word of a fast speaker. It is called stenography, or shorthand. An almost lost skill nowadays.
"There is a fifth, undefined group, representing 10%, which the algorithm is unable to classify in relation to a clear type of behavior."

They are divergent :-). I found the characterization of "Envious" as people who always want to win a bit more charged than "Competitive" would have been.
>expect BSODS

I wrote a (unreleased I believe) filesystem with this a couple years ago and my machine would reliably BSOD every time Windows tried to do the mandatory automatic updates. My friends say you can disable that but I haven't used Windows often enough since then for it to be a problem.
> Before he worked for Apple's call center, Ben* had a clean bill of mental health

Employee complaints of all sorts.
There is Adrenaclick. And 2 generics for it.

(So all you have to do is convince your doctor to write Adrenaclick on your prescription and you can buy the generic for $145 at Walmart)

That price is interesting because it puts some kind of cap on the amount that regulation is leading to the price increase for Epipens. The regulation about substituting Adrenaclick on a prescription for Epipen can be argued, but any doctor that won't write Adrenaclick after a minute of discussion better have a good reason.
The problem is the compatible hardware is in there, the driver exists, it's just disabled in bios. If you hack the bios to flip the bios setting linux installs fine.

I don't think many would care, but the lenovo 710s has some pretty unique hardware. Nice intel CPU, nice intel GPU (iris 540), and a nice matte screen.

The Dell XPS 13 is similar, but to get the nice cpu/gpu you have to get a shiny/reflective screen that cuts your battery life almost in half (22 to 12 hours).
Flickr Has a Market Place?

I Bought License for Photos from at least 25 different Photographer by emailing them (on Flickr Mail). Never knew there was Market Place :)
ElegantJBI in Gartner Competitive Landscape BI Platforms/Analytics Software
"Sola dosis facit venenum": https://en.wikipedia.org/wiki/The_dose_makes_the_poison
It's only profitable to sell $6 sandwiches if... 1. you use unpaid labor (family) or 2 you have 1,000+ franchisees.

If you are low volume, you're gonna have to sell at $8 - $10 to make something worthwhile.

Now, I get it, they are unquestionably overcharging for this drug and delivery system. I just don't think you can say that since I can make something at the rock bottom price of $x that someone else should be able to make a living (or run a pharma corp.) by selling at a similar price. The sweet spot is somewhere between $30 and $300, where it is is probably closer to $100.
Er, the compatible hardware is in the lenovo laptop, it's just disabled in BIOS.
Whonix and Tails are OSes, meaning they could override what the browser tries to do in terms of network access. If Chromium prevents a plugin from directing all traffic to SOCKS, just take controls of Chromium's network settings from the underlying OS (Whonix, Tails).

Note: This just answers the question about browsers or other pieces of software that don't allow control of their network components. It doesn't address a vulnerability in that software.
Please read up on scene referred to display referred transforms. You can read about them at http://cinematiccolor.com, which has a Visual Effects Society endorsed PDF available.

Ultimately it depends on what aesthetic you are aiming for and the context you are displaying it.

You don't truncate, you map.
The reason I was looking at the Lenovo 710s instead of the thinkpads was specifically because the 710s included a nice intel GPU (iris 540) and not a nvidia chip which hugely complicates power management, drivers, etc.
FWIW, LD50 dosage is low for intravenous injection, but very high (multiple orders of magnitude higher) for intramuscular injection. The risk is generally not getting enough of a dosage, not too little, unless you somehow manage to hit a vein.

The main problem is that, if you're carrying around EpiPens for allergic anaphylaxis, particularly for a child, dealing with syringes and bottles isn't really a practical solution for day-to-day living (and definitely not an option if you're carrying them around for yourself -- hard to carry out delicate medical procedures while being unable to breathe). There are probably a lot of people without access to autoinjectors who have had to suffer the consequences of anaphylactic shock.
Generic Adrenaclick is $145. Maybe some of the rest of the $455 difference can be explained by regulation, but a lot of it comes down to Mylan choosing to price the drug that way.

You can also look at Mylan offering $300 coupons to consumers to get them to utilize their insurance. Maybe they are just incredibly generous, but it's more likely that they are happy to net the $300 from the insurance (in other words, they profit at $300).
"Optimistic, Pessimistic, Trusting and Envious" in case you missed the obvious
like myself.
Talking about dislikes of the article, this was my second time skimming through it. The first time around, I just didn't get through it fully because even though it was just a "3 minute read" according to Medium, there was too much unrelated fluff that didn't keep me engaged in it. It seemed quite unfocused due to the writer's penchant for seemingly amusing or funny anecdotes. The second time I read it, I again skimmed through all the fluff looking for the pieces of value. This article could definitely have been written a lot better in a focused way and explained Bloom filters a lot better for the same "reading time". I'm going to search for something like that, which I'm guessing is already out there.

I generally have a dislike for articles on Medium because many that I've seen look like lightweight pieces with very little value and too many words. The way images are displayed is also kind of disturbing to me. Articles either seem to have some gawdy, blurry, shaky, seizure-causing GIFs or blurry images that come into focus only after some scrolling. In my experience, Medium was good and different when it started, and seems to have become worse in quality and presentation over time. Maybe it's a temporary phase. Maybe it's not.
The Curious Genius of Amar Bose
https://en.wikipedia.org/wiki/Epinephrine_autoinjector#Socie...

"Mylan's efforts to maintain its market dominance were aided when Sanofi's competing product was recalled in November 2015 and further when Teva's generic competitor was rejected by the FDA in March 2016.[76]"

http://www.fiercepharma.com/sales-and-marketing/fda-swats-do...

Yes, you can load a precise dose into a device, but the device has to actually work, reliably and consistently. This is apparently a hard problem, for at least two Epipen competitors. Since Epipen has no serious competitors for a device like this, they get to charge as much as they dare.
If there were an open-source low/no calorie formulation of MegaBrand Zero that didn't contain carcinogens, I'd try that out.
> Competing auto injectors have not been as accurate and simple to use, is what I've read.

Also legally EpiPen must be fulfilled by a brandname version instead of alternatives, and alternatives are scarce due to the difficulty of passing regulatory approval: http://slatestarcodex.com/2016/08/29/reverse-voxsplaining-dr...
Verizon is good about sending text messages when you get close to limits.

Not sure how people didn't notice...
Well, these guys aren't psychologists: they are physics PhDs doing (judging from the name of their group, Grupo Interdisciplinar de Sistemas Complejos) some work with agent-based modelling and game theory. They seem more like econophysicists (or economists) than psychologists.

I don't think this categorization is gonna get popular enough to hit the tabloids (you won't be filling up quizzes to see whether your significant other is 'Envious' or not), but it might be relevant to social science.
Those X-ray machines are not DIY. They are specifically designed for the purpose. And FDA requires reporting from manufacturers.

http://www.fda.gov/Radiation-EmittingProducts/RadiationEmitt...
>You didn't have it, by any current definition of the disease (Canadian/Fukuda criteria).

I'm not sure how you can determine that from the parent comment.

>"Chronic fatigue syndrome" is an unfortunate misnomer - fatigue is one symptom but far from the only one.

The parent comment never said he/she only had fatigue. In fact the mention of "symptoms" would kind of imply that fatigue wasn't his/her only symptom, wouldn't it?
Actually, people thought he forked the wrong repo because he forked the browser, not the Tor node repo... and then he finds this bug in the browser.

I suspect that wasn't planned, but regardless, he did fork the "right" repo.
I find it absurd I have to count gb on a monthly basis to not get charged data overages in this decade. I literally use my phone lightly and one wrong mistake can throw my entire family plan into a tail spin. I manage 7 lines and it's a full time job. Every change on my plan seems to throw Verizon into a major rework of my bill and subsequent phone calls to have the changes reverted. I'm all too familiar with creating customer service tickets, miscalculating promotional data, complaining and receiving credits. I feel like I might know Verizon's plans more than Verizon. It's enough to make me not want cellular data.

Comcast has a mesh network in California I literally have free wifi (as a paying Comcast customer) anywhere I go. Definitely not a plug for Comcast as they are effectively broadcasting paying customers internet to freeloaders like myself. Morality of that is another debate though
Yes, the article even uses programmer and engineer interchangeably, so it advises you not to call yourself an engineer either!

Why do I keep seeing people comment without reading the article at all...
The only thing I really want from Sublime (or VSCode) is an API that lets me display an output panel/sidebar with an html engine embedded in it.

Atom provides this - it also provides arbitrary html in the editor itself which is cool but also what makes it slow.

I just want it for the supplementary panels that show build outputs, documentation or other contextual information.

That's enough to let me customize it for our team's usage.
As far as I've been able to tell, the patent is on an improvement to the needle cap.

The precise and reliable dosing mechanism is out of patent.
> The OP specifically mentioned "immune" and "metabolic" dysfunction, not symptoms.

Fair enough.

> The symptoms, abnormalities, triggers and cures match perfectly with what you would expect from exhaustion due to chronic stress.

Based on your research, what are the cures for "chronic stress"? The treatments discussed in the PACE paper (CBT, GET, etc.)? I'm genuinely interested -- my sister was diagnosed with CFS over a year ago and has made little progress since then.
A task rabbit? Is that what you call a subordinate at your office? Am I totally missing this?
If you have 10 customers an hour on average and you pay some guy $10 an hour to make 10 sandwiches, then your costs at $4 per sandwich. That means you have 33% headroom to pay rent for your business, which is better than what McDonald's has. McDonald's has decent pricing because they shoot for like 28% and a lot of volume (much more than 10 customers an hour and probably more hours than your business).

A soda machine is basically free money because syrup and water cost pennies. The cup is the most expensive thing you give to the customer for his $1.99 soda.
Somewhat tangential: I surmise that this title will be subject to editing by HN staff, but I think that "Hacker group creates $30 DIY Epipen to expose corporate greed and save lives" is an exemplary post title for HN and want to see more like it.
That's a very strange definition of "weakest" you're using there.
That's an odd slippery slope argument to make on a site called "Hacker News."
Anything we can do to improve the usability and detection of licenses is a big win in my book. Even the best intentioned people have a hard time consistently doing the right thing -- whether that's attributing the right copyright owner, reproducing the right copyright message, or otherwise abiding by the license, it can be hard to be 100% correct.

It would be nice if this was more programmatic. If licenses had an identifying string they carried so they could be clearly and consistently identified, and machine parseable metadata. If we make it easy to build automation around license files, we make it easy to do the right thing -- maybe even easier than doing the wrong thing.

I think about something like Webpack. If Webpack could just traverse your project structure and parse all your dependencies license files and generate the proper attributions, that would be amazing.
"The LD50 value for adrenaline in control animals was 11.1 mg/kg b.wt" http://www.ncbi.nlm.nih.gov/pubmed/6087619

That means for an average human, LD50 = ~10 x 70 = 700mg... or perhaps more for typically overweight Americans.

Conclusion: Scare factor is being used to justify the market... you have been had.
> if you sort of detach yourself and look from a business perspective and value-based pricing, Epipen competes with the ER, and $600 is a bargain vs an ER visit.

This is exploitation of inelastic demand (death is a pretty high priced alternative to $600), and it's pretty clear that's exactly what government regulations and market controls are supposed to protect against.
KDE 2 Screenshots (2000-2002)
Maybe I am misinterpreting your second point, but there are absolutely unique and consistent dysfunctions of ME/CFS sufferers. One example is severe exertion intolerance - this is not present in most other diseases. Generally, if we exercise more than a small amount we are literally bedridden (sometimes hospitalised) for days or weeks. It's often used as one of the diagnostic criteria. Psychological illnesses generally respond very well to exercise, and ME/CFS doesn't. It's a good way to rule out ME/CFS. There are also consistent immunological abnormalities (low NK cells for example), and recently the metabolomics study.
Not sure how that's greed as much as a case of too much regulation.

Companies exist to make a profit, why are we getting upset when they do so within the confines of law? Here, the law allows for lobbying and high regulatory burden which creates a monopoly for EpiPen.

I don't expect public shaming to reduce corporations from seeking profit. I do have great hopes for reforming laws to incentivize competition so that the desire for profit benefits us all.
Can you state your stance on AGPL[1] on the website like MongoDB and RethinkDB do to put people's minds at ease.

[1] https://github.com/deepstreamIO/deepstream.io/issues/298
"This guy" used to run his own business and also did consulting when the article was written
https://www.taskrabbit.com/
Wow, is that a freemen-on-the-land open source project!?
Pepper – a friendly contact widget for your website
They need more than my name to run a credit check. They need something they're not going to get, which is my SSN.
Dell has 2 XPS 13 options.

1) Great battery life, lousy cpu, nice matte screen, not much ram available.

2) Half the battery life, nice cpu (i7-6560), nice GPU (iris 540), and a 3200x1800 reflective screen that reduces your battery life from 22 hours to 12.

The Yoga 710s (sadly with the broken BIOS that prevents linux from installing) is much like the theoretical XPS 13 without the power sucking 3200x1800 display.

So I was just looking for a decent laptop, decent build quality, and wanted to avoid the pain/suffering relating to trying to get nvidia working with a laptop that sleeps, switches to the internal intel on battery, and has some stupid system for moving pixels from the nvidia chip through the intel chip to get to the frame buffer.
The fund generated an annual return of 5.5 percent between 1 January 1998 and the end of the second quarter of 2016. After management costs and inflation, the annual return was 3.6 percent.

https://www.nbim.no/en/the-fund/return-on-the-fund/
The problem is that if an auto-injector is truly needed (onset of anaphylaxis), there may not be much time to futz around with it, if it doesn't work properly.

The auto-injector apparatus is not regulated because it is dangerous; it is regulated because a failure to operate would be dangerous. It is regulated for reliability.

The hacker/maker ethos is awesome and drives a lot of innovation in our society, but sometimes there is also a need for careful engineering and rigorous testing.
> I disagree. It is very easy for me to modify Linux. I just don't have the skills to do deep modifications.

Part of this is that setting up a development environment is kind of tricky.

> And i don't think languages really help here.

They really do actually.

> Directly, what sorts of edits do you wish you could do, but feel prevented from doing?

Imagine an OS where you can do something like "view source" with html, you can edit it, and immediately re-execute it. I think that the list of things I wouldn't look into tweaking would be shorter.
Might as well follow up with "why are desktop apps so badly designed...?" Web technologies are certainly their own specialization, but UI/UX is bad for a most user-facing software, regardless of the technology used to present it.

Web technologies don't make UI/UX harder (in a lot of ways, they make it easier!). There's just a lot of them, and they've become dominant for the vast majority of things the vast majority of users experience.
TOO COOL FOR SCHOOL Double Long Lash Shaper
I am much more concerned about social/ethical/cultural problems in general. I think if those problems were solved, all other issues with effectively evaporate in a very short time, because we waste a tremendous amount of energy on, well, random crap.

Sometimes technological/medical/governmental/etc. changes do move the social forward so there's hope there.
How is this relevant to the article
I like to call it "free as in WinRAR".
Good point. Although again, adverse incentives on Lemonade's side are supposedly handled by the fact that they're a nonprofit.