skysight-inc/HackerNews huggingface dataset:
You should check out the research cited on Vitamin D in the first link: "vitamin D supplementation decreases all-cause mortality in adults and older people"

While it certainly is possible to "get vitamin D" by going outside, that doesn't mean it's enough.

The leading theory as to the advantage of having white skin is that it assists in providing more vitamin D in latitudes without as much direct sunlight. This means the amount you get by "going outside once in a while" is not sufficient (otherwise we wouldn't need the advantage of getting as much as possible)

Likewise, drinking coffee removes calcium and vitamin d from your body, so it is wise to replace them, especially if you drink a lot of coffee.

Also, while I might not "need" to supplement them because I am getting "enough" that doesn't mean I won't benefit by taking more. Indeed, we're talking about Nootropics here, not just staying alive.
This happens in non-solo founder companies too. In fact, I would expect it to happen slightly more often in companies with multiple founders, because they jockey over what the roadmap should be. When there's a lack of leadership at the company it's a big problem, but it happens at all types of companies, not just small solo founder startups. I think you are conflating the problem with the fact that there is only one founder.
Yes, can you describe your SPF library? I'd love to learn more about how using a VM / state machine paradigm could help me approach CS problems.
Okay, then expect expensive drugs for decades when it costs billions in R and D and the drug companies need to recoup the
The last two seasons went all in on the tech/super-AI plots and dropped the "crime-fight-of-the-week" tedium. I'm actually pretty happy to see it talked about so well here. The last season was kind of emotional and definitely struck at my techie core.
What is the point of exposing a scheduler? Seems like that's another implementation detail that should not be exposed. The user should just instantiate some fibers and go.
I would go and say that when flickr will be gone we will enter a different era of the web. Flickr has been such a great influence over the years that internet without flickr will be a different internet altogether
I would never discourage them, audacious goals are how real change is achieved.

But in the history of the world, every time you conquer one disease, a worse and scarier one seems to fill the void. And if you wanted to get pedantic, it could be said that Humanity is a disease of the Earth. Eliminating that infestation might qualify under the goal. Perhaps AI is not going to solve the problem by eliminating disease, but eliminating that which can be diseased. Kill the prey, and the predator dies.
I bet you could go from main() to displayBufferOnScreen(unsigned char *buffer) in a couple dozen lines of C using SDL.
The article didn't really clarify the actual reason for me. They cited difficulties against competitive platforms, but is it because
(a) their technology wasn't as good as their competitors
(b) their compensation plans/margins weren't as good as their competitors, or
(c) there really wasn't interest from the photographic company for such a service, and there weren't enough users to keep it viable?
No, they use the admin access they obtain from you to modify the system so they can obtain admin access again in the future. They do not ever have your admin password.
or·gan·ic dis·ease
a disease in which anatomic or pathophysiologic changes occur in some bodily tissue or organ, in contrast to a functional disorder; particularly one of psychogenic origin.

(this is the medical definition of "organic", which is completely different to the chemistry definition, which I think you confused it with).
Wasn't that discredited? From your link:

> Other research has cast doubt on a link between Toba and a genetic bottleneck. For example, ancient stone tools in southern India were found above and below a thick layer of ash from the Toba eruption and were very similar across these layers, suggesting that the dust clouds from the eruption did not wipe out this local population.
The regulation is necessary because of the number of bad actors in the industry. From experimenting on people under the guise of vaccination programs through cherry picking of results, drug and technology companies have proven time and time again that they can not be trusted to put human welfare ahead of profits.

How do you prove a new product from a hostile industry safe, without having regulations covering the types of tests and acceptable reporting necessary?
I like implementing emulators, because the toolchain and architecture specification are all there already. You get to implement what is basically a little embedded CPU.
The phrase you're looking for is "Regulatory Capture"
I need my web fed notifications.
Don't even need to use humans, I tried something easier -- http://github.com/peterldowns/clickbait-classifier
> one of those is what actually happens

No it’s not. If the heads aren’t moving in lockstep, what actually happens is you’ll extremely rarely have a moment of time when both locations are whole numbers.

At one moment you have { head1loc=0, head2loc=4.17 }, head #1 reached the cell position on the tape, head #2 is still moving. After a while, you’ll have { head1loc=0.872, head2loc=5}, head #1 is on its way, head #2 reached the cell position.

Looks like for a Turing machine with two asynchronously moving heads, there’s no usable concept of “state” at all. That’s very close to what happens when doing actual parallel programming on real hardware.

Good luck applying your idea of computation as a sequence of state transitions to that.
This doesn't feel like the right platform for DIY. When someone needs an EpiPen, it's because they might be dying. Presumably, a large and well-capitalized organization will have tested their device extensively and can offer better guarantees about it actually working (I should stress presumably). There are a lot of ways in which the hacker mindset can be beneficial to society, but this particular application feels like an ethical gray area.
Yes, exactly. Unless everyone has some skin in the game, the research will be biased towards curing those with money, perhaps using the rest as guinea pigs.
We know there were multiple dispersals out of Africa, but we can trace our ancestry back to a single one.

How does that work? Everyone else died? What about recently discovered groups like the Red Deer Cave People? https://en.wikipedia.org/wiki/Red_Deer_Cave_people

Doesn't evidence exist that groups interbreed, at least Denisovans / Neanderthals / Modern Humans?
I remember looking at the distributions for Meyers-Briggs quizzes on OKCupid...

They were not Gaussian distributions :)
My son, like all 4 year olds I think, are fully human, in tune with the moment, developing ego but still open.

I picked my son up from school and we were playing, then I reached for my phone, noticing the shift in his facial expression from happy to subtle concern and disappointment. He knows that device creates distance in real life.

Then we discussed some topic that I decided could be better handled by Youtube. As soon as the video started he got sucked in and I let him watch a couple vides then had to pull him off the thing, which he promptly forgot about as that was the past.

I'm sure the reason I noticed is this thread got me thinking. But beyond that it occurred to me that there should be some sort of code. Other people might have a different code but I hope to god we all could at least share item number 1. I think that prison is too soft a hell for someone who kills another human because they were texting or any other distraction. Let me know if someone already has a better list on Huffpo or somewhere.

1. Harm none. The most obvious implication of this is NEVER, EVER, touch your phone while driving. Pull the fuck over. Don't take a chance on killing another human being for digital crack. The rest is subordinate to this first principle. I don't use any devices while driving but I'm writing it down to reinforce this, helping me to resist temptation.

2. Choose who you're with. Don't use the device for more than the most basic communication (i.e., coordination of plans) when in the presence of other human beings, especially my son. Sure, snap a couple pictures but put it away and leave it. My son is 4 and so it's more obvious that if I'm on any device, I'm valuing that activity over him. I feel I learn something about human beings here that should be obvious because a child is the base we come from.

3. Have fun and keep learning. Online's awesome.

Ok, it's a pretty thin set of principles that took me a few minutes to compose, but it'll serve my purposes until I'm ready to add another item but it's very likely that other items don't need to be codified. I wonder if making a list like this is a thing or am I a nut? Maybe both...
I bet that hurt real bad.
This is a fantastic project. FWIW, Paragon's extfs for Windows uses either Dokany or the original Dokan, so at least one company thought this was good enough to use in production.

I'll just point out for anyone interested in trying this, expect BSODs: https://github.com/dokan-dev/dokany/issues/344.

I'm also not sure how the Win10 Anniversary driver signing changes have affected the project - they're relying on a commercial sponsor for the signed releases.

Alternative: https://github.com/billziss-gh/winfsp

Paid alternative: https://www.eldos.com/cbfs/

There have also been a number of other discussions here, but I should get back to work instead of digging those up.
I wonder if he has a staff at all? If not, then it's even a more impressive body of work!

I'm pretty sure that when Matt wrote for http://dealbreaker.com/ he did it without any support staff. It was probably that gig that got him noticed by Bloomberg.

I'm a fan, to be sure

You can always go back in the Dealbreaker archives and read his earlier stuff. It's pretty equivalent to what he now writes for Bloomberg View.

It's a long strange trip for him from "high school Latin teacher": https://www.bloomberg.com/company/announcements/matt-levine-...
> Is there any way to disable this, or set it manually at least?

It looks like they try to read `LICENSE`, so maybe if you avoid using the American spelling and just put `LICENCE`, github will skip it. I know gitlab had this bug/feature.
There are accelerated approval processes for precisely what you're describing. Section 505(b)(2), for example, allows an applicant to rely on studies conducted for a previously-approved drug with the same active ingredient. And of course the whole ANDA generic approval process.
If you don't code around gamma then don't bother reading? I mean it says in the title, right there "about gamma", I don't see how that's drawing anyone else but the intended audience. I don't even deal in the article's subject matter but still found it interesting, informative, and well written; I think the condescending intent is coming entirely from you.
> Where?

I was imprecise. The chipset supports a Linux-compatible option, were it not explicitly disabled in the firmware.

> Lenovo has issued a formal statement denying it.

They deny purposefully disabling Linux, and I don't have any evidence against that denial. They don't deny disabling AHCI, because they clearly did. In the disassembly of the code: https://lnv.i.lithium.com/t5/image/serverpage/image-id/76843...

Intel's RAID is implemented in their driver. Switching the option from AHCI to RAID switches the disk controller's ID so it doesn't bind to the OS's standard driver (whichever OS that is), and binds to Intel's instead (assuming it's present). Intel provides its driver (and only for Windows), Lenovo locks the option so that hapless users mucking about in the UEFI settings don't make their machines unbootable.

Lenovo can deny "deliberately blocking Linux", but they can't deny "practically blocking Linux".
That page on its own already looks refreshing compared to the stuff I usually see on the subject, I'll look into it, thanks!
Another super fun, pretty intellectual form of sports/exercise is climbing. It always seeming like the physics and engineering types gravitate towards it, and I can attest it's another excellent way to get some exercise and to have some fun working on "problems".

As tech workers, I think I would even beyond sitting in a chair all day being physically insulting, to say that it's perhaps one of the greatest (and really a non-trivial one) occupational hazards we face.
Okay, then expect expensive drugs for decades when it costs billions in R and D and the drug companies need to recoup the costs (in addition to the red-tape involved in releasing the drugs).

Many countries with cheap drugs never had to pay all of the research and development costs.

If it's not government greed, it's government ineptness and the inability to understand how the market actually works.

The generic company in this article, for instance, never had to pay any R&D costs for the proprietary epipen applicator and can easily charge a much lower amount of money for a generic version (which is different).

The high cost of FDA approval also creates monopolies, because it's very difficult to get anything to market. To get better and cheaper drugs, we need to change this at the government level.
At this point, any new OS that wants to breaks away from Unix/Windows and hopes to gain mass adoption, will need to come with an Unix/Windows emulation layer built-in.
The arrangement of "Daddy's Car" is lovely. It was done by a human btw.
The hack here is simple: this group did not get FDA approval for their device. Greedy corporations have repeatedly tried to make money by competing with Mylan with cheaper Epipens, but they've been prohibited from doing so by the US government (not so in Europe, where the unfortunate Europeans suffer eight greedy corporations trying to drive prices down).

http://slatestarcodex.com/2016/08/29/reverse-voxsplaining-dr...
I dropped Verizon about 3 years ago for Net10 Wireless. Net10 offers "unlimited" data even on their cheapest plan, which is basically full speed for the first 500MB of data, and then 2G speed after that. Even though 2G speed is borderline useless, there are never any overages. I've been paying about $35 USD for the cheapest plan.
I too felt the same. The intent is good - but the idea that someone could/should rely on a DIY EpiPen doesn't jive well with me.
In 2016, shouldn't we be using public/private key pairs instead of passwords?
ESP8266 WiFi Display
Beginning VR Development (2015)
Thanks for the reference. For those like me who'd not heard of it, see [1] for a description and links to many implementations.

[1] https://en.wikipedia.org/wiki/Earley_parser
Safari has barely any market share, so definitely no.
While I agree for people who can afford it, this is probably aimed to people who can totally not afford the real deal and would be left with nothing otherwise. Also it is a hack, since the best way would be to reduce the price of the good one.
Why is the chat necessary? Can't you just give a rough estimate based on zip?

Show me a number, boom! done.
Watch the video. All described is loading epinephrine into an autoinjector. This is great because it suggests the barrier to competition is relatively low hanging fruit for those already in the drug delivery markets.

Also: screw mylan
I think they're usually done with a specific FSM, rather than general regular expressions.
I can't source it right now, but somewhere I read something along the lines of: "studies show 3/5 epipen usages are done improperly and are ineffective"
Income Increased
For better experience across desktop and mobile, I use Telegram. It doesn't need a phone to be around after a one-time activation and also allows a passcode to be set to access messages on the desktop.

I have also started using Wire for the same reason, and even better, since it offers end-to-end encryption by default.
Did the OP edit the original comment? I don't see any mention of race and the OP is just stating he is impressed by how Norwegian women take pride in doing even the most menial of jobs (which is something I noted too when I was there).

Just found it strange how did you come to the conclusion of a "racial underclass" when there was no mention of it so i was wondering if it is an american thing.

Note: While not as multi-cultural as the US of course, Norway is not exclusively a "homogeneous" society and in fact, I just noted that almost 1/3 of my Norwegian friends are not "Nordic born". You obviously haven't been there if you made that conclusion yourself.
7 Ways to Get Vector Icons for UX/UI Design
Wow, this isn't just me! I got tired of it and just switched back to the default theme.
In the "Top of the World" graph in the article, there's a dip for Saudi Arabia. Does anyone know why?
Wonderful example. Literally taken, they're nearly after immortality. But of course, you shouldn't take them literally.
Hacker mindset doesn't mean a duct tape solution.
The problem is, in my opinion, that the average person will have no concept of how to manage a public/private key setup.
The headline says "to expose corporate greed"

The premise is that $57 was the old price. and they bumped it up to $318.

And a DIY group can pull it off for $30, without economy of scale.

From wikipedia "In 2007 when Mylan acquired the rights to market the product, annual sales of all epinephrine autoinjectors were about $200M and EpiPen had around 90% of the market; in 2015 the market size was around $1.5B and Mylan still had about 90% of the market"... $1.5B annually... So if FDA testing costs them $10,000,000 anually, thats still less than 1% of their revenue.

That means that with economy of scale, and dispersing the cost of testing over several million sales, they could easily produce a product for $30. But they don't because they dont really care about saving lives, they care about getting paid. They would prefer people die than them make less money.

Completely not about "hey do it this cheap easier way" but "heres the rock solid proof that a $300 (even $60) EpiPen is stupid"
I mean, the whole point of regexes (not to be confused with PCREs) is that any given regex is isomorphic to some canonical finite state machine. It is, specifically speaking, a tiny description of an FSM over the alphabet of ASCII characters (or whatever charset you're using).

Interestingly, regexes/FSMs are (IIRC) the most powerful class of machines for which equivalence is decidable. So if you give me any two regexes, I can tell you if they match on all the same strings, but this is not true for any more powerful grammar.
I interpret this as more of a political statement, rather than something you'd actually want to rely on.

That said, it looks like this is just reusing an existing off-the-shelf autoinjector used for insulin. If it fails, you could remove the needle and inject manually. The biggest risks I see here is making sure the epinephrine stays sterile, and that the dosage is correct. (To be clear: Either of these could have serious consequences.)
The value of money in a technology career
I'm aware, I read the post.
There's a pretty decent hex editor plugin for sublime:

https://github.com/facelessuser/HexViewer

I've used it, and it's quite nice, but I don't know how it'd handle large files. Maybe take a look?
This part is great and deserves more attention:

----------------------------

This isn’t a great injustice only to programmers, but instead to all “non-bullshit” contributors to society. But this is a problem with our brand of capitalism, not with software engineering careers.

Let me explain. Ask a teacher, police officer, or firefighter if they are paid proportional to the value they add. Ask a great professor who has educated Nobel laureates whether they are paid even 20% more than their mediocre colleague who can’t even give a lecture to students.

Instead, most people are paid for political reasons or due to closeness to market transactions. For example, stock brokers don’t add much value to society overall, but are very close to market transactions for pricey financial instruments, and so they can skim off them. CEOs of BigCo’s are paid well for the obvious political reason: they sit on the board of a company with the people (board members) who set their salary.
Regarding the original price hike which motivated this project, I saw an interesting perspective on the matter: https://www.youtube.com/watch?v=RoMlxVimwiU

Now granted Shkreli is a controversial figure, but basically drug companies are businesses, and if you sort of detach yourself and look from a business perspective and value-based pricing, Epipen competes with the ER, and $600 is a bargain vs an ER visit.

And of course his ultimate conclusion is that maybe life saving drugs are more like water and power than cell phones and wine? Maybe the government should get involved in making generic drugs available.
It can feel like "flu with a hangover", that's my experience too.

In my case that's triggered by too much activity. I've gradually learned to stay within my limits most of the time, so these days I don't have the flu feeling as often as I used to. Although I have to limit activity to a handful of hours per week in order to keep it at bay.
Part of the issue is the incentive system at work. The FDA isn't really rewarded for getting a drug to market quickly, but they are punished politically when they approve a drug that is later found to have problems.

This means that they are incentivized to be cautious, sometimes excessively so.
I do want to agree with you, and while watching the video I thought a lot about the risks involved. However, the realities of the world applied to ethics requires me to disagree with my knee jerk reaction. The fact is that many families are dealing with the fallout from the fact that they can't afford these life saving devices, and this option gives them a reusable $30 solution to the problem (the needles can't be reused, but the spring can). This is important given that they need to be replaced every year, apparently.

The not-so-grey ethical issue is the cost of these devices, and the fact that there are people who are too poor (medicare doesn't cover them, according to the article) to get them. Until we build a system that prevents this unjust situation, it is my opinion that there is nothing questionable about this 'hack'.
People interested in these things should look up GLR and GLL. Pretty powerful when I studied them.
In my locale, a problem with soap is soap scum, due to hard water. My household uses all detergent based "soap" because of this.
with no survivors :^)
But then you'd become fingerprintable by staying out of the crowd
Majority of the so called "luxury taxes" (that were really named so) existed maybe one or two hundred years ago, mainly targeted then-existing aristocracy, but most of such special taxes are long gone. (Maybe the after-effects are still showing up in weird places, like your clerk's imagination...) One gem was the literal "tax on fun" (which applied to cinema shows and dance halls), but that was discontinued in the 1950s. I guess only "luxury taxes" that we have now are quite "normal" by Western standards, like sales taxes on confectionery and alcohol and cars.

More recently, a couple of generations ago there might have been import tariffs on consumer electronics...?

I can't think any other tax on the product itself than the regular 24% value added tax. (Of course, the indirect ones, like income tax paid by employees, tax on corporate profit, etc probably show in the final price.)

Foodstuffs do have lower VAT rate (around 10%), so maybe the clerk was thinking about that, but that difference doesn't explain a 5€ -> 100€ hike. Maybe you just managed to wander to the most expensive retail store in the downtown and had an unusual camera model...

Finland is expensive place, but most of that caused by more mundane reasons than special "luxury tax", like indirect taxes, regulation, and shipping costs raising the general price levels.