skysight-inc/HackerNews huggingface dataset:
"Furthermore, we found strong similarities in what may be called the 'gut profiles' of the Crohn's-affected families, which were strikingly different from the Crohn's-free families."

It seems that fecal transplant (or pills based on them) can alter/fix gut profiles[1]. I wonder if someone tried fecal transplant to cure Cron's disease.

[1] https://youtu.be/e_dF1N-Ckbw?t=1m44s

Edit:
It seems this has been tried and pretty successful[2].

"A recent publication in the journal Inflammatory Bowel Diseases titled, “Fecal Microbial Transplant Effect on Clinical Outcomes and Fecal Microbiome in Active Crohn’s Disease,” reports seven of nine patients with Crohn’s disease were effectively treated using FMT in a Seattle Children’s research study."

[2] http://pulse.seattlechildrens.org/study-suggests-fecal-trans...
Agree on short reading articles. How about longer size content? And have a direct correlation / Math formula between how much time you need to "invest" consuming the content vs how much time you need to "spend" up-front in unlocking the content: micro-payments vs ads. Would that work for you?

And, regarding the payment, would you connect with Apple Pay or Amazon Payments or PayPal instead of providing publishers your card directly?
'Pokémon GO' Has Been Dethroned in the App Store Because It's Poorly Monetized
You've been able to configure your own tsc for a while, at least in IDEA anyway.
> Sure, my point is that RDBMS are not better they are different.

I can't see any way in which the relational model, either abstractly in or practical application, is less suited to any task than the hierarchical model, and its clearly better suited for many tasks. Its both different and better. The hierarchical model is, especially given the alternatives that existed at the time, good enough for some tasks, sure.

There are alternative models that are better suited for some tasks (e.g., graph model), at least on a pragmatic level, but I don't see that the hierarchical model is one of them.
Control-flow analysis? I think that was Flow's differentiating feature.

Obviously, there are still differentiators between the projects (like TypeScript including a known set of transpilers vs. Flow delegating to Babel), but I'm curious to know if they are converging on their core feature (e.g. how to do type-checking/static analysis).
Alas, another victim of media hype.
Not so dumb after all!

Blo-cker! Blo-cker! ... who o o uh-oh!
G - E G - E A C D E-D

(Repeat, ad nauseum).
Author here. Yes this is a significant price to pay, but being able to test once and be sure that your users' experience will match your testing is worth a lot. It should be possible to have an updater that avoids downloading the main chromium dylib on most updates.

This is actually not based on CEF, btw, but on libchromiumcontent (the Electron alternative to CEF).
> I don't have any moral problem with ads and companies need to make money so I don't have an adblocker and I just don't visit sites with obnoxious ads.

How do you keep track? What about drive-by exploits that could infect your computer on first visit? Or mobile ads that redirect to the app store?
But it's all or nothing right? If I write a new component in a pre-2.0 codebase and want strict null checks, I can't get them.
As a publisher, even I find myself using ad blockers on certain websites that are totally unusable without them.

One problem is that most sites seem to think of advertising as adding value for themselves and the advertiser. Advertising can and should actually add value for readers with a good example being the job listings here on HN.

I think some % of publishers will have to try and adopt better advertising practices (plus maybe offer some additional paid features), and those that do will be able to survive.
The problem with current approaches is that they are trying to parameterize higher order functions of highly evolved organisms. But real intelligence is an emergent property of self-replicating organisms, so you aren't going to have true artificial intelligence until you have real synthetic life. Maybe instead of simulating a mammalian brain distinguishing between shapes we should be building yeast.
Does it really work?
I love reading these write-ups. These guys have amazing skills!
I actually never got the popup. IBM Model M is PS/2 not USB so it has to be plugged in on boot as the UEFI/Bios won't let you hot plug.
Norway's been tightening the mortgage belt for years now. You can only borrow less than 85% of the purchase price of the house, excluding fees. That was set in 2012 IIRC. And now (from January 2017) there will be a complete ban on interest-only mortgages (even just for limited time periods), and a hard cap at total loan amount (including also student/car loan etc.) for each family not exceeding 5x total gross income.

Source: am planning to buy a new house, had a meeting with my bank man two weeks ago.
I was just starting to get into his old podcasts when he was interviewing Bas Rutten and started saying how cutting out gluten made him a hundred times more healthy and fixed all his ailing woes. I couldn't believe some of the stuff he was saying it fixed. It was at least a bit funny because I guess Bas knew it was all BS since he uncharacteristically goes very silent while Joe peddles the anti-gluten bandwagon. I stopped listening after that.
The best thing to do is compare your results to a widely known dataset with information about the accuracy rate for what you implemented. That will give you a baseline to figure out what, if anything, is going wrong.

> Wrong algorithm?

Almost certainly not, Bayes is a very solid classification technique.
That might be a cut and paste TOS, with a little CTRL-H for flavor. Otherwise, that TOS hopefully is intended to apply to the website only.

If anyone has gotten far enough with them, I'd love to see their actual insurance contract. I'm too lazy to go pull their state filings.

EDIT: Here's the part that troubles me more -

"GIVEBACK
... our stated intention is to calculate the amount of leftover money by subtracting from the group’s collective premium, our flat fee (currently 20%), the costs of claims, a “rainy day fund” and other insurance expenses like reinsurance – and giving back what’s left (up to 40% of the group’s premiums). ... "

That 20% "flat fee" is about 8% less than the industry standard expense ratio. That's pretty aggressive expense reduction, to the point where I'd wonder if they'll run out of money, or if they plan to write only the most preferred of preferred risk. I know it reads as though a "rainy day fund" and reinsurance are separate items, but a rainy day fund only happens if you run a surplus, and I'd be shocked if anyone is reinsuring this block at reasonable rates unless, again, (very) preferred risk - at which point you wouldn't want or need to reinsure.

I know it sounds odd, but as a startup, I'd be happier as both a potential customer and potential employee (both very hypothetical) if they called it 30% and undershot it. You don't want to run out of money. It's not an industry where you can just fire some employees unless you're really overstaffed, since service level declines drive complaints, and enough complaints and suits put you out of business.

EDIT 2: All of that said, I'm rooting for these guys. This industry needs modernization pretty bad. If they can make their 8% back from process and tech optimization, that's great. I'm not trying to be negative, I really want them to succeed.
Fair point, but it's not a restaurant and educating readers this etiquette would be really tough. How about pay for reading and refund if you think it's not worth your money? Would you do that?
> However this is wholly about how competition and status seeking are channeled.

You can't truly channel competition anywhere because it's always routed to itself. Competition implies a provider of gifts and those who chase those gifts. The provider will always use faulty proxies to determine who to provide to, thus becoming disproportionately important to the process. Acquiring the gifts is always disproportionately more important than anything else. Status is one such gift, with no redeeming value.

Competition is always about the agent that is winning, and the provider that arbitrarily bestows prizes. That is where the focus lies by definition - the objective of a competitor is to eliminate all others, not to produce anything of value. Science should be about the results, and should bow to no provider.

> They are instincts, they come naturally.

A lot of bad things are caused by instincts that come naturally. That's actually specifically why I pointed those two out: they're natural, and they're extremely dangerous and we should always be aware of them creeping up and keep them in check.

Instead, we created whole institutions to worship them.

> Clearly in the present order they are not channeled in ways that lead to superior or interesting outcomes since mediocrity is everywhere.

The "mediocrity is everywhere" thinking is part of the problem, as it drives everyone to worry about how "mediocre" they look and rush after the best thing ever all the time, instead of calming down and doing the right things. Publishing a failing study is mediocre. Helping people in need is mediocre. Doing a little bit of fitness to keep yourself healthy is mediocre. Yet, that is exactly what we need more of.

Mediocrity will always be everywhere because it's a mathematical fact - most people are in the middle. So, yes, it's everywhere. That's tautological.

I think you were trying to say something else.
Please stop. We ban accounts that continue to violate the guidelines like this.

https://news.ycombinator.com/newsguidelines.html
For a guy that has in the past railed against the Red Hat/Gnome people, Rasterman seems to have become very corporate in recent years...
Funny how all the original markup and languages are becoming the machine code of the web. No one writes js anymore, just compiles into js. No one writes css anymore, just SASS -> css. Html? Nope, directives or shadow dom.
You are the ad blocker! But really don't worry, it's nothing new. The 80s and 90s were filled with advertisements-as-TV-shows.
A better comparison would be "anti-American," which to me does have a clear meaning.
The mention of sonar sensors, used to prevent the car from running into obstacles, made me think the author was planning to make the robots autonomous too, but maybe just hasn't gotten that part worked out yet. I was also curious how the robot would know when to stop and try classifying something, without the operator explicitly telling it so.
Yes, I tried "no implicit any" and got nothing working. Problem were mainly 3rd party libs with out-dated, bad or no type definitions.

Is it even possible to use these flags with production code?
PLUG – The World's Most Powerful Battery Pack
Bingo. The article disproves something no one I am aware of has ever asserted (except perhaps the author).

Following your passion leads to happiness.
This is an interesting comment. It could be summarized as: "1. Some people are idiots; 2. The people in this article aren't idiots, have done their homework, and are getting this mostly right. 3. Still, some people are idiots."

The secret to substantive discussion on HN is having the discipline to address the specifics of what's interesting in a story, and resisting the temptation to let loose on unrelated idiocy. That's hard, because letting loose on unrelated idiocy feels good. But it stuffs the discussion with junk.

(This is a general point, not just about your post. If everyone did it the way you did we'd all be much better off.)
The Computer History Museum has some special interest groups: http://www.computerhistory.org/groups/

If you're in the SF Bay Area, I'd also suggest seeing the 1401 in person on Wednesdays (3:00 to 3:30) or
Saturdays (11 - 11:30) - see also: http://ibm-1401.info/
Seems the spread operator (a roadblock for a lot of JS interop) will have to wait until 2.1.
Being able to pass the buck to IBM if things go wrong was actually the theme of IBM's ads in 2001. In a typical ad, the CEO is getting blamed because the system is down / can't be upgraded. CEO: "And whose job is it to make sure all this stuff works the way it's supposed to?" Assistant: "That would be yours." Tagline: "And that's when it hits you, you are so ready for IBM.”

(Of course I have to admit they were successful ads if I remember them 15 years later.)

Links to the ads: http://www.landscapesofcapital.com/items/show/893
http://www.landscapesofcapital.com/items/show/888
Hiding your light and floating with the tide (because you were too afraid to "fail") can be a sure path to even more systematic failure, also. As the King of Fun himself so presciently put it for us, just as he was setting out on his path:

And indeed, that IS the question: whether to float with the tide, or to swim for a goal. It is a choice we must all make consciously or unconsciously at one time in our lives. So few people understand this! Think of any decision you’ve ever made which had a bearing on your future: I may be wrong, but I don’t see how it could have been anything but a choice however indirect — between the two things I’ve mentioned: the floating or the swimming.

Per last month's discussion on "On Finding Your Purpose: An Extraordinary Letter by Hunter S. Thompson" - https://news.ycombinator.com/item?id=12379809
Good luck getting some complex problems on irc / stackoverflow.
(Disclaimer: Ozgun from Citus)

I'm not a video person, but when I watched this one, I was quite impressed. I feel this may be one of those rare occasions where the blog post title can't quite capture some of all parts in the video.

https://youtu.be/JAPl4eNFxk4

I think the really impressive part is what happens for you behind the covers. MX sets up replication, auto-failover, backups, pgbouncer, monitoring dashboard, etc. for you through the click of a button.
After Samsung's awful rollout of the Note 7 with battery problems, and the costs of bringing a product to market without enough testing, I have some sympathy for this slow Play on Chrome OS rollout.

If there are end user problems running Android apps on a Chromebook, it is better to have a smaller and more manageable test set of users.
Show HN: Introducing EmbedBox, Our Open-Source Embed Code Install UI
I saw some comments in TypeScript code-bases, that excluded parts of the code.
What's the alternative term you suggest? "People reaching young adulthood around the year 2000" seems a bit verbose.
disable specific opcodes alltogether

That would be network censorship and kind of ruin the point of a "trustless network".
Yeah. "Millennial" is the catchier brand name for what was at one point being called "Gen Y". It's essentially a born on or after 1980 catchall
Magic_get: static reflection for user defined POD types
There are actually 10+ independent implementations of Ethereum (including one in Haskell):
https://www.reddit.com/r/ethereum/comments/3pdskt/how_many_e...

This was part of the development philosophy, to implement the client (based on the yellow paper http://gavwood.com/paper.pdf that specifies the protocol) in multiple languages in order to find bugs: if 2 clients don't agree on something, then we found a bug.
Thank you. I really hope that you set the trend.
it's that worst of them are aggressively misaligned with my interests and with the interests of anyone who's not a total fucking rube.

It makes sense that so many are targeted at rubes. Who else do you think are actually clicking ads?
> Even still, TextMate is a substantially more carefully designed tool.

Do people still actually use TextMate? Judging by their website [1], for example the screenshots taken under an ancient version of OS X, I thought it'd been abandoned years ago. The last post on the blog is in October 2014.

[1]: https://macromates.com

[2]: http://blog.macromates.com
I find it endlessly amusing you're hypothetical for non-verbal consent is literally theft.

However, I agree; taxation is necessary for government to exist. I'm also not an anarchist. I see taxation as a necessary evil, but I refuse to not call it what it is. Like the case with most (all) necessary evils, I consider it a moral obligation to advocate for it's conservative application. So, sorry you find it offensive that I want the government to steal less of your labor. I hold no grudges towards people that would like to see their labor partitioned towards public works to whatever extent they see fit, but I maintain coercion is immoral.

Lastly, the "just move argument" is a real gem. "Don't like police brutality? just move." Talk about letting your privilege show...
Stealing Machine Learning Models via Prediction APIs [pdf]
That's assuming losing the content creators serving ads would be a loss for internet users.

Given that there exist people that hold this opinion, their own view about using an ad blocker is not at all in the same context than in the prisoners dilemma.

Thus the dilemma is biased, to an extent directly proportional to the number of people holding this opinion.

If it is biased, the standard game theory analysis does not apply directly. i.e. the best move might not be to suffer ads for no long term gain.

More prosaically, I do not care in the slightest if people living in selling ads disappeared completely from internet. They are a cancer, ads are a cancer to the utopia that internet was for a short time.

We need come back to this state. We will, actually, by empowering users.
Removing ads isn't really tampering though: it's inarguably improving.

If someone makes my life immeasurably better without telling me, I'm thankful.
Thanks. How about responding to the support requests I already submitted?
What if what you love is terrible?

http://i.imgur.com/GripW3M.jpg
We've updated the title and detached this subthread from https://news.ycombinator.com/item?id=12557290 and marked it off-topic.
We've removed nearly all the implicit anys from DefinitelyTyped, so if you're getting definitions from there, you shouldn't see any.

We don't have good data on this but my perception from talking to people on GitHub is that the vast majority of people using TypeScript run with 'no implicit any' on once they get their codebases converted.

(I'm on the TypeScript team)
"Don't like police brutality? Just move!"
I don't know — I pursued engineering and am ultimately not passionate about it. Going to work every day is often a drag.

Why do I want my kids to make that same choice? Only for financial reasons.

Only.
> And your first point basically reduces to: it's more immoral to develop a cure and make lots of money from it, than to spend billions on activities that don't even cure anything. That's absurd.

Did the American company invent stents and was just protecting their R&D returns from evil Russian copycats? Also the "active suppression" issue is here - apparently the company bribed the government to prevent the competition. The point is more like "it's more immoral to be a life-saving cure provider who decides to make more money from it by shutting down competition that can provide that cure cheaper, than to not be in the life-saving business entirely".

> The money invested in Twitter's IPO alone could've saved more than half a million kids from malaria.

True only if taken out of context of the economy at large. There was no point in time where someone could make a business decision and whole money invested in Twitter's IPO would go directly to cure malaria. That money was not controlled by Twitter, but by many people who invested in it, each having a personal choice of what to do with their wealth.
Teaching Unity to Non-Programmers: Playground Project – Unity Blog
I agree with your response to the poster above, but I'm glad he/she made that post because it is an important point that I didn't see anybody else make.

I have no reason to doubt the OP's assertion of corruption in the Russian medicine market, as I have worked with several people who did research in the US and practiced medicine in Russia and have heard similar stories from them.

However, the OP's assertion that more stents = more lives saved is not entirely true as you and the above poster point out. They are clearly well studied and known to save lives, reduce long term morbidity from heart failure, etc.. in the setting of STEMI (ST elevation myocardial infarction, in other words a big acute heart attack).

However, a large number are placed for angina and many studies have shown that they may not make a difference. There are risks with the procedure of placing them, the issues of having to take blood thinning medications afterwards, and so on.

I guess the reason I wanted to comment is to expand this discussion a little because more stents (as the OP wants) in Russia doesn't necessarily mean more lives saved, but it does mean more business for OP. I do not know if there is such a shortage of stents in Russia that emergent catheterization is avoided, if someone knows this to be the case please correct me.

Also, I don't want to come off as implying that the OP is corrupt or only in it to make money. Medicine is complex and (at least in my current opinion) probably benefits from a business side seeking to maximize profits through innovation as long as it is countered with health care workers (and I guess federal oversight) scrutinizing things towards the patient's best health to act as a counterbalance.
> I like to say that CEOs should do only three things; recruit and retain the team, build and evolve the long term strategy and communicate it effectively and broadly in the organization and externally, and make sure the company doesn’t run out of money.

I've been hearing more and more of this, and experiencing this first-hand; it's so true. Communication is often left out/undervalued in early stage startup blogosphere.
Also when scaling, not just when rotating. Take a look at this one in H5mag (top-right hamburger turns blue occasionally when resizing the window): http://jouwlater.h5mag.com/denken_en_doen/cover
On Computable Numbers [pdf]
This very thing has occupied my day job for at least four months now. It happens when a pre-existing system one has to improve has lots of DB-heavy and compute-heavy operations commingled.
Cool feedback. Thank you! This approach doesn't get you to subscription (although technically it could), but rather allow you to read without unblocking or whitelisting adblockers, and without subscribing or sharing your personal data.
I've been using this in beta for some of my personal projects that run on hobby dynos. This doesn't actually give you the certificates, it just allows you to upload the certificates you get elsewhere to heroku and then configures the server for your heroku app from there. I find it very helpful to be able to do this for free... for some of my hobby projects, it's cost prohibitive to spend more than a few dollars a month on SSL.

If you want to get the certificates for free as well, there's a guide at the link below that can help for setting this up with Let's Encrypt. The title is "LET'S ENCRYPT WITH A RAILS APP ON HEROKU", but I followed mostly the same steps for a Flask/Python app and it worked fine. The only step that was Rails specific was for setting up a route to the verification content, which is pretty easy to do in any framework that I can think of (to verify the website's ownership, Let's Encrypt makes you setup an endpoint at <your-site>/.well-known/acme-challenge/<verification-string-they-give-you> that simply returns a long random string they give you in the CLI). See: http://collectiveidea.com/blog/archives/2016/01/12/lets-encr...