skysight-inc/HackerNews huggingface dataset:
True, but there are many people who have EpiPens that don't "need" them per se. I have one for my daughter, because her mom (my ex) pressured the doctor to prescribe them for her, even though all she had was a small rash on her face when she ate her very first egg. (the doctor said Benadryl was sufficient for that) Since then I have (with a great bit of care, and an EpiPen handy) given her increasingly large doses of eggs, never seeing a problem, till she now eats eggs like everyone else. But still her mom is fearful and gets new EpiPens prescribed every so often.

The point is, it isn't all black and white. If a kid has a severe allergy, sure, make sure you have a real EpiPen and carry it with you always. For those borderline cases, well, something like this might be fine. Having it reduces a really small risk even more.

Another interesting point: even if a kid has a severe food allergy, they are still more likely to die from a car accident than from an allergic reaction. Some people lose perspective.

http://well.blogs.nytimes.com/2013/12/06/food-allergies-less...
1. grpc is unstable for online service.
2. grpc has poor performance.
3. I can't find some advanced usages in examples.
Yes, that is the conclusion that he reached: that the government should just nationalize generics for public benefit. That's sort of the extreme version of mandated pricing.

Someone else in the comment section shared another perspective which reaches the opposite conclusion: that these regulations have created the problems in the first place, and the government should not touch this sector at all: http://slatestarcodex.com/2016/08/29/reverse-voxsplaining-dr...
>Not to mention the CEO is a senators daughter.

So? Is she just not supposed to work?
That was my reaction when Bill Gates said he would fight malaria. But then his funds really made a difference. "Cure all disease before 2100" does not seem an impossible goal and helping scientists build tools globally usable is actually a very good angle to help the medical community.

Reading the article made me think that Zuckberg did his homework and may be able to spend money in an area that makes a difference over time.

You know, I still hate Microsoft and Facebook, but if Bill Gates or Zuckberg decide to spend a few billions on medical research rather than on a fleet of private jet or personal theme park, I'll join the choir of applause.
It's rent, opportunity cost, insurance, litigation, brand awareness, promotions, etc. Sure a McD can operate at that level because they have efficiencies and have bargaining power and arbitrage. A standalone shop doesn't stand a chance of being economically viable for an independent owner --you don't want a pharma which barely scrapes by. You want healthy ones but not ones which are willing to unjustly take advantage of their customers/patients.

Anyway, my main point was that ingredient cost is only one part of the cost of making/delivering something.

IIRC, restaurants aim for foodstuffs to amount to 30% or less of sales to be viable.
To be fair, every other major renters insurance company requires a lot of personal information up-front before giving you a quote. I don't see why this should be different.
Let me get right on proving other people's arguments.
> We use an open source Ruby gem called Licensee to compare the

> repository's LICENSE file to a short list of known licenses [...]

I have seen more people putting the license of their projects at the end of the README.md than in an individual LICENSE or LICENSE.md file which is what this feature analyzes. I noticed the addition of this feature a few days ago while checking the repository for the Atom.io project, but without an official blog post I was left thinking why none of my repositories (which are MIT licensed) were missing it. I guess reading LICENSE(\.md)? is good enough.
Twice Exceptional (2e) Children
> It doesn't matter whether you call yourself a programmer or an engineer

Did you read the article? He does not suggest calling yourself an engineer as an alternative to calling yourself a programmer
Sort by reputation – what's the most reputable iOS news site?
Where do you get your iOS news? Please rank these 10 in the order of authority from highest to lowest. Thanks for your help/opinions!

http://cultofmac.com
http://iclarified.com
http://idropnews.com
http://imore.com
http://iphonehacks.com
http://macrumors.com
http://appleinsider.com
http://iphonelife.com
http://9to5mac.com
http://macworld.com
I must admit that my reply was narrow-focused on Mylan not being able to pin the costs on compliance. After a re-read of your original comment, I see exactly the point you're making. You're right. The reason Mylan jacked the price up isn't directly due to their costs of compliance, it's related to the industry's cost (that is, any potential competitor), and the competition that is stifled because of it.

Your point about handling the injections the old fashioned way is a good one as well. But it's worth noting that diabetics have tons of experience self-injecting using standard needles and vials. A typical Epipen user has probably never had to do so, and when the drug is urgently needed is a bad time to get started. So for these users it's not simply a matter of convenience.
awful. and relatable.

CFS was my brother's diagnosis, until it became lyme. others take a psychiatric slant. "sorry, we really don't know how to treat this yet," or even "sorry, we're not really sure what it is, but we believe it exists" is somehow an impossible conclusion. the only thing shared by his GP, internist, CFS specialist, psychiatrist, and lyme specialist, really, is a kind of diagnostic hubris.
How is this relevant to the article?
Glad to see the callout to QA your game with people who are outside of not only your physical experience (different heights, ability, VR tolerance, etc.) but also your personal experience (gender, life experiences, technology expertise).

VR experiences can feel vastly more real than other games, and it can be jarring to have a presentation of the self consistently out of line with your own self image. Ensuring you present the player with either something comfortable for them, or something deliberately challenging (ie, if you are going to make the character you inhabit male, it should be a deliberate choice knowing that there may likely be significant discomfort for some of your audience.)

Don't assume that a virtual body/archetype that you are comfortable with maps to something that everyone is comfortable with!
If you are persistent, you can get CVS to order the "generic" epinephrine injector for $5.

https://www.facebook.com/barbara.k.hollinger/posts/128523673...
Heh, well there's a small footnote. Microsoft loves Linux users.

So sure, they want ubuntu to run on windows, so they can get into the container market.

So sure they will sell office in the cloud to target the legions of chromebook users. Not that they would ship office for linux.

Nor would they consider supporting linux on their surface books.

The locking linux out of various platforms with EFI seems to be progressing nicely.

But sure, microsoft will meet you half way to steal your customers and try to find out some other way to lock them into a microsoft platform.
Kayaşehir Yeni Escort Balıketli Eve Gelen Sedanur
The Simplest TODO List with GitHub Oauth, Deploy with Heroku
Ask HN: Have you used eclim? How is the experience?
Here is my rank:

1) http://cultofmac.com
2) http://iclarified.com
3) http://9to5mac.com
4) http://macworld.com
5) http://appleinsider.com
6) http://idropnews.com
7) http://imore.com
8) http://iphonehacks.com
9) http://macrumors.com
10)http://iphonelife.com
The Onion must've renamed itself NY Times.
World of Warcraft Legion Serial Key Generator (PC/Mac OS)
Uh actually most people on here understand you don't hack "mission critical" (involving peoples' lives).
Start-up sells a stamp-sized Linux server for $5
People need to eat, pay the bills.....

I doubt donations would be even half of what his creator is getting now.

$70 dollars is already pretty ok, considering I was paying above 150 with student discount on the mid-90 for software tools.

Why this urge to get stuff for free, yet wanting to sell own work.

And yes, I do donnate to all FOSS projects relevant to my work, as if I had bought a license.
Did you automate the NAS -> Google Photos upload? Does the script resize the photos to keep within the "free storage" requirements?
Url changed from https://www.minds.com/blog/view/625077755582623755, which points to this.
In a way, the rest of the world is indebted to the U.S. for its regulation. It's a huge and wealthy market, so manufacturers have an incentive to enter it; the regulation is hard so products often really have to improve to get through.

The rest of us can then enjoy greater safety of pharmaceuticals and medical equipment without setting up such an expensive regulatory system.
I am jealous of those students. I would love to take that class.
Oh man, you should take a look at NIH gene data someday if you really want to blow a gasket. Pretty much everything is over 1GB, and there are many, many files to work with when you're really only looking for a very specific subset of the data. I remember helping a friend of mine who's a grad student with them for his research.
Yes, the bed was quick, and in the first six weeks there is some fussing, but the pattern gets established quickly if it is routine. I may have been lucky with all three; we never had so much fussing.

Waking up every 2 to 3 hours, but mildly and not turning on lights or getting up for a diaper change.

My son was only one who really cried, but usually during the day when overtired, or gas, or whatever. He didn't cry when in bed at night.
Hmm, rasterizer was just a starting point for me on the way to understand "how browser works".

Having just a rasterizer is like naked VM without bytecode compiler.

So I decided to add HTML/CSS engines to it.

But if you have HTML/CSS then why not to add scripting to it? So added VM executing bytecodes, GC and compiler producing those bytecodes. Having VM I thought that it would be cool to have built-in persistence in it - you need to persist UI state somehow, right? So it got integrated NoSQL database on board.

That's pretty much how http://sciter.com was born.
>Based on your research, what are the cures for "chronic stress"?

Well the first thing is to obviously get rid of the chronic negative stress. However even then, many people don't recover (hence the fact that they have long-term CFS, rather than a temporary burnout which they then recover from after removing the stress).

As for why people don't always recover after removing the negative stresses? I think there are a couple of possibilities:

[1] Negative stress from the illness itself (a vicious circle).

[2] The brain gets stuck in the fatigued state, until it gets a "kick" out of it, in the form of a positive stressor. (Basically the fatigue state is a protection mechanism against negative stress that the organism can't cope with, and it requires evidence of a positive development in the future outlook in order to remove the "brakes").

Even though I suffered from CFS, it's hard to pin down exactly which one makes most sense. However the effective cures seem to address both (i.e. getting the patient to do a positive activity). (I should clarify that there are no truly effective "official" cures, only unofficial ones that people like me and others figure out by ourselves).

The problem is that CBT and GET aren't based on valid etiologies of the illness, so at best they might be a placebo that just happens to kick the person out of the exhaustion state on some occasions. The problem is that CBT and GET can be inherently stressful (especially if the person is convinced of an organic etiology), which will likely just make things worse.
You might enjoy my Automated workflow with Synology and Goolge Photos.

https://medium.com/@jmathai/introducing-elodie-your-personal...

https://medium.com/@jmathai/my-automated-photo-workflow-usin...
The inductive invariant is the correctness property itself (when all processes are done then at least one y is 1) in conjunction with "for all processes, when the process is not on line 1, then its x value is 1". You can probably replace the second conjunct with "for all processes, if the x value is 0, then the process is not done", but the proof gets a bit harder.
We are working on it. [0]

[0]: https://github.com/Microsoft/vscode/issues/12163
What's the Best Anti-Spam Plugin for WordPress?
> it always has to load the entire file before displaying the first line. Aren't there some editors that don't have to do that?

http://www.ultraedit.com/

ST is neat. UE is heavy duty.
Here is how I automated Google Photos and my Synology.

https://medium.com/@jmathai/introducing-elodie-your-personal...

https://medium.com/@jmathai/my-automated-photo-workflow-usin...
YouTube enlists volunteers to moderate site via “YouTube Heroes” program
That's why I made the remark about drugs, alcohol or hypermobile sleepers. My current wife, myself and my ex-wife never had an issue before babies, during and after.
The state transitions can be partially ordered, but the way this works in TLA is that every computation is a set of legal behaviors (sequences of states).
Hackers Remotely Kill a Jeep on the Highway
Not sure if this is what you're asking, but if fund returns are random but different, then someone is going to have the best performing fund.

Let's say the best performing fund is (fictional) Xanadu Investments we'd ask, how do we explain Xanadu's performance.
> With these latest changes, Sublime Text 3 is almost

> ready to graduate out of beta, and into a 3.0 version.

Wow, Finally! I have been using ST3 for several years (wow, years) and always wondered what is keeping the developer from labeling that version as stable. From all the issues reported here [1] I have never encountered one while using the editor for pretty much all my work. Those $70 are definitely worth every penny. Sometimes I cringe from videos featuring ST while using a non-registered license, this week it happened with a course from Google engineers via Udacity, Google engineers!!! As if they don't have miserable $70 to buy a license, I assumed they were in a rush and didn't have time to set the license which I hope they bought.

Anyway, thanks for all the hard work Jon, and recently Will.

[1] https://github.com/SublimeTextIssues/Core/issues
Personal attacks, which this is, are not allowed on HN. Please post civilly and substantively, or not at all.

We detached this subthread from https://news.ycombinator.com/item?id=12552687 and marked it off-topic.
You could skip writing a bootable kernel, and try that with microcontrollers :) It's possible to hook up a tiny lcd screen to an arduino
I don't think such a system would work out, or at least it would breed a huge amount of resentment towards it. Vaguely reminds me of Legalist philosophy: it attempted to "abolish penalties by the means of penalties", that is, through a liberal use of (capital) punishment not only for criminals but for their whole families, so that no one would dare commit a crime.

https://en.wikipedia.org/wiki/Legalism_%28Chinese_philosophy...
Ask HN: How to spend 6 months (personal development)
I've decided to take a break from the job market for half a year to devote some time to personal development. While part of it will undoubtedly be spent exercising, learning to play the piano, biking, meditating and playing video games - a non-trivial chunk of it will be dedicated to professional development. Ideally, I'd like to come out of these 6 months with one or two new marketable skills, but more importantly to hopefully rejuvenate my love for programming as a craft.

To this end, I would love to hear your suggestions & feedback. Anything is fair game - from self study, MOOCs, structured courses - literally anything that can be reasonably accomplished within a 6 month timeframe. I do have some specific areas of interest, but am very open to hearing about others I might not have even considered. For the sake of this thread, budget is not a concern.

My background :

full stack developer w/ 5 years experience, having variously worked on web dev (front, back) & windows desktop applications

Examples :

* Security - OSCP certification; Coursera MOOC on Software Security or Hardware Security
* Mobile Dev - Big Nerd Ranch, books & courses
* Game Dev - Build Unity 3D desktop game(s), presumably mostly self study
* VR Dev - Unknown

I'm also considering putting together a reading list. Historically, however, I think I've learned best when using books as a reference point to aid in projects and not so much a primary resource. That said, I'm absolutely all ears for tome recommendations as well :)
> but there are absolutely unique and consistent dysfunctions of ME/CFS sufferers

But the exercise dysfunction is not consistent. Sometimes it's immediate, sometimes it's 24 or 48 hours later.

>Generally, if we exercise more than a small amount we are literally bedridden (sometimes hospitalised) for days or weeks

That's the problem - it's not always like that for all patients.

>Psychological illnesses generally respond very well to exercise

Not exhaustion from stress. (And it's not entirely psychological, there are various types of stress, some physical). You have to get out of this mindset of physical vs psychological. Stress is both.

>low NK cells for example

That is not consistent, and it is also a feature of stress (which significantly affects NK cells).

>recently the metabolomics study.

which has not been replicated, and which is showing different results to another metabolics study just released (see discussion on healthrising and phoenixrising).
This is by design.
oh wow. That sounds horrible. I am sorry man!
Please don't post unsubstantive comments. Also, please don't post comments complaining about downvotes; that's explicitly against the site guidelines (https://news.ycombinator.com/newsguidelines.html).

People often feel that their pro/anti MS views are being suppressed by the anti/pro members of the community, but really it's just that the community is divided. Accusations of abuse without evidence aren't allowed here, and someone merely holding an opposing view isn't evidence.

We detached this comment from https://news.ycombinator.com/item?id=12551876 and marked it off-topic.
Related to a lot of discussion comments, I highly recommend "A Random Walk Down Wallstreet" by Burton Malkiel. https://www.amazon.com/Random-Walk-Down-Wall-Street/dp/03933...
Right, but something 90% effective that you can afford will save a lot more lives than the 100% effective version you can't.
> I think the first thing people should be taught about concurrency... is when not to use it.

Concurrency is usually not a feature of the algorithm but a feature of the problem domain. If you have many requests coming in at the same time, all competing for a limited amount of computational resources -- you have concurrency.

How you handle it is a different matter. You can decide to handle the requests one by one, but then, by Little's law, your throughput would be very low, and your server will crash if the rate of requests is over some small limit (which depends on the time it takes to service each request).
>with a lisp-y syntax it would probably have died a sputtering death

Tell that to 30 years of Autocad users.
Careful engineering and rigorous testing does not require FDA approval. Hackers and makers can do their own rigorous testing and publish their methodology, which can be scrutinized by peer review.

What's unlikely is that a DIY production scheme can ensure consistent manufacturing quality, since the careful, rigorous hackers are not going to be making this for everyone.
This 13-Year-Old Makes Products on the Web
I agree with you completely. At some point the laptop became 'the default computer'. I went laptop-only for most of the span 2006 - 2011, before adopting a workstation (with dual 1440p monitors, a nice keyboard, a mouse, and my precious Linux) as my primary computing device again.

I couldn't go back for anything. I simply couldn't. I have a fairly light and portable laptop with a 13" screen that I carry around from time to time, and it's a vastly more constrained computing experience.
Yeah it was mentioned here already: https://news.ycombinator.com/item?id=12536932
I'd agree with that. There's a general feeling that people are surprised when their insurance companies pay out/cover some big cost (like rot), rather than it just being part of life. That says something about how much we trust existing insurance companies.
I think they meant rasterization as in http://www.scratchapixel.com/lessons/3d-basic-rendering/rast... instead of in the context of browsers...it's not a very precise term
Lexus LFA 2014 HD Wallpaper
Autoinjectors for other drugs sell at $33 retail: http://www.buyemp.com/product/meridian-auto-injectors

They (including epipens) probably cost about $10 to make. That's total cost, from production to delivery to the retail outlet. They would have been handsomely profitable at the old price of $57.
It so happens that I grew up in the south part of Silicon Valley between Blossom and Almaden Valleys: the Quicksilver mines have contaminated a number of streams and waterways in the area to the point there are permanent signs indicating fishing is prohibited due to the risk of mercury poisoning. The former mercury mines are also a local tourist / educational attraction and recreation area.

Also, there's widespread arsenic contamination of American-grown rice, due mostly to North American geology and the quirks of rice biology. [1] As such, you'll probably want to cook American-grown rice not in a rice cooker, but in a coffeemaker. [2]

Finally, another important advisory for transplanted Valley people whom enjoy the hiking the hills like the Stanford Dish area are the pervasiveness of tiny deer ticks which have been known to carry Lyme disease.

0. https://en.wikipedia.org/wiki/New_Almaden

1. http://www.consumerreports.org/cro/magazine/2015/01/how-much...

2. http://time.com/3974793/rice-arsenic-coffeemaker-cooking/
I have to say, I'm pretty excited by this. Mutual insurance companies have existed for a good while, but they're not easy to find. Having one that's married to great tech definitely makes me want to use it.
CRISPR is quite promising.
Meyers-Briggs are gonna be suing these guys for sure.
Perhaps it's a situation where there is no outcome where the barrier to entry is too high for bad actors while simultaneously being low for good actors.

The current solution seems to be to increase the barrier until the bad actors are gone; as this means there is less finger pointing.

Going the other way would seem to take active effort from a political representative, and the outcome will end in deaths directly attributable to them.... which would be career suicide.
Based on the implementation of regulation in the US, I'd say the purpose of regulation is clear: To make a monopoly / oligopoly on drugs.

> It is regulated for reliability.

Then why aren't the tests and methods of testing reliability required to be published?

> it is regulated because a failure to operate would be dangerous

The risk of not having it at all far outweighs the risk of the injector failing.

Not to mention that regulated injectors fail too due to manufacturing defects.

> sometimes there is also a need for careful engineering and rigorous testing.

But should that need preclude private individuals from assembling their own life saving devices on a small scale (1-10 units)? We're not talking about someone else stealing your design, process, research, and building their own production line here.

Furthermore, careful engineering and rigorous testing is needed when you're creating a production line of these things. A competent individual can assess and test their own device. Yes, it's more time consuming, but for something as essential as a life saving drug, it's probably worth the extra time.