skysight-inc/HackerNews huggingface dataset:
Ooof, this is a deep topic and people bleed all over it when running a SaaS company. I used Pin Payments (nee Spreedly Subscriptions) for Appointment Reminder. You will probably end up using Stripe's subscription feature, which has some (but not all) of this logic baked in.

> What happens when credit card is declined

You retry the card on three consecutive days (many declines are due to network or balance issues) then start emailing the customer about it. After a few emails you escalate to phone calls. Except, you don't do this -- you use Churnbuster to do this, because for a pittance they will make you thousands of dollars a month at scale. (Churnbuster assumes you're going to be using Stripe... but you should use Stripe.)

> What happens when they downgrade the subscription

Judgment call here: do you want to do a pro-rated refund or a pro-rated account credit? e.g. If someone changes from a $100 plan to a $25 plan halfway through the month, we observe that they've consumed $50 worth of services and have $50 remaining, which we could either a) send them back on their CC and bill them normally from here out or b) give them an account credit for $50, which will cover their next two months of service, then bill them normally.

The case for the account credit is largely "it optimizes for your cash-flow management as opposed to their cash-flow management." (This can be important in corner cases like e.g. switching from $5.5k for 12 months to $1k per month in month 2. Which, by the way, annual to monthly pro-ration logic is something you're going to probably have to write.)

> How long should the data be retained in a suspended account

Judgment call; I default to "indefinitely unless legally required otherwise or requested otherwise." Many customers will come back to you a year later and _expect_ that you still have their account on file. Customers who are more privacy conscious will tell you; you can delete their account then. (Note that deleting an account is largely a feel-good measure for the customer and accomplishes epsilon from the privacy perspective. There are probably 1+ people reading this who disagree with this assertion, so riddle me this: what happens to our last 2 years of backups when I delete an account? Do I re-hydrate all of them, run the delete SQL, then re-backup and blow away the old version? Nope. Do I toss 2 years of backups because a $29 account churned? Umm, nope. We have your data at least as long as our data recovery window and it is probably recoverable for longer than that, and us deleting an account does not change that.)
What would be the layman-evaluatable criteria for using it on a person with no history of allergy?
The petition to Congress mentioned in the article:

http://www.petition2congress.com/20720/stop-epipen-price-gou...
You might want to look at Envato's Themeforest and CodeCanyon
what happens if someone goes into anaphylaxis?
I agree it would be useful to have. There's all kinds of stuff like that in academia. So many different forms and tools that the problem would likely be the time available to assess them. On top of nobody using or replicating them as usual. :)

Note: sklogic did mention doing something like that by making sure all the programs' had a scriptable API then using basic, shell input and output to test them. There were acceptance, testing tools I used a long time ago that did something similar using XML. Not sure the efficiency of this method but it should work.
The article reminds me of the part in the trilogy where a huge chunk of Antarctica breaks off and sea levels rise by meters in weeks.
(One challenge: though neural networks generalize very well, we still lack a decent theory to describe them, so much of the field proceeds by intuition. This is both cool and extremely bad. “It’s amazing to me that these very vague, intuitive arguments turned out to correspond to what is actually happening,” says Ilya Sutskever, research director at OpenAI., of the move to create ever-deeper neural network architectures. Work needs to be done here. “Theory often follows experiment in machine learning,” says Yoshua Bengio, one of the founders of the field. Modern AI researchers are like people trying to invent flying machines without the formulas of aerodynamics, says Yann Lecun, Facebook’s head of AI.)

One of the most interesting aspects of the field - we don't have robust ways of predicting what will work without trying it.
Qualcomm announces an ARMv8 server chip
Evidence for Africans in Britain from the Bronze Age to the Medieval Period
The only "safe" way to configure traditional (not per-priority) pause frames is to configure the switch to ignore pause frames coming from hosts, and to configure hosts to obey pause frames coming from switches. With data center bridging and per-priority pause, some of that goes out the window.

In the early days of 10GbE, I did drivers for a NIC that had a very small rx fifo. In some cases we had to advise customers to enable pause frames, otherwise the NIC would be subject to tail drops when the switch burst traffic to us. I still feel kind of bad about giving out that advise.
> Also going away are the company’s enviable working hours. Carson says he’s rolling back the company’s 32-hour work week, where he and his employees took Fridays off.

Let me find his blog post about that 4-day week. Oh, there it is...

http://ryancarson.com/post/21708810513/4-day-week
> So, The FDA, because they require drug and device makers to demonstrate efficacy and safety by going through a rigorous clinical trial process, are evil? Really?

Yes, if the process is so rigorous and expensive that it drives the cost of drugs beyond the reach of people who need them, and it hampers the effective functioning of the free market. And I think it's widely accepted that's far more expensive to bring a drug to market here than it is elsewhere in the world.

The FDA believes its mission should be to ensure that drugs are safe and effective. That is wrongheaded. Instead, it should undertake a rational risk/benefit approach. Rather than saying that no drug gets through the filter unless it's safe (as demonstrated through reams of evidence), it should ask, how much risk should we tolerate in exchange for how much benefit?

In the case of Epipens, there's little risk, because epinephrine is an old, widely-used drug. There is some risk that it will be mis-administered by a less-than-perfect device, but the fact is that a $10 bottle of epinephrine and a $1 syringe can save a life. It is offensive that the FDA thinks it should get in the way of the distribution of such things.

I was in Colorado last summer and took my son horseback riding. Our tour guide was allergic to bee stings, but she was just scraping by financially, and couldn't afford an Epipen. She'd been stung before, and her throat had tightened, but fortunately she happened to have an old, expired pen from before the price went up and so she survived. But now she was going out bare. We gave her one my son's pens. It won't last long. It's possible that she won't last long either.

You want evidence this is an evil system? There it is.
"write thin C++ but use C++'s features "

Well, that's good given I previously told you that your best approach to memory safety... given C++ use... was to convert it to C to run through Softbound+CETS or something similar. Alternatively, a C++ to C compiler then that. I wonder what the state of C++-to-C compilers is these days in terms of what they take in and quality of output.
it's gotta be obscure if the Chrome Windows process stops responding, don't you think? (as the article reports).

Or is that just the Chrome team following the letter and the spirit of the law? "if they want a PAUSE by God they'll get one..."
Do these things actually cost more than $100 to manufacture? The US isn't subsidizing the rest of the world with this, we're subsidizing the shareholders of a single company.

I've seen this argument made regarding American health care costs in general. Everyone else pays much less because we're subsidizing them, the argument goes. Except that American medical R&D spending is about $500/year per capita, while the gap in health care costs is thousands. That's some combination of waste and people getting rich off of other people's suffering.

This product could pretty clearly be sold at a profit at the old price. But they can make more money if they charge more. People will die because they can't afford it anymore? Fuck 'em, apparently.
> thankfully adblockers block Tealium tag manager by default anyway

Most ad blocker do not block Tealium by default. For blockers such as Adblock Plus or AdBlock, one must explicitly enable EasyPrivacy (which is enabled by default in uBlock Origin).
It's a really difficult balance to strike with the FDA. Too strict and you get situations like this, too lenient and you get thalidomide. It's hard to come up with a single set of rules that will rush forward all good, effective medication, block all dangerous medication, and continue to do so despite constantly changing technology and understanding.

Clearly the epipen thing is a huge problem, and if the FDA can fix it, they need to do so ASAP or be ordered to do so by Congress. But I'm hesitant to say that their only motivation is petty bureaucracy.
Lay speculation here:

If the first run is on a 28nm process, does this suggest the second generation on e.g. Intel's 14nm process might yield a drastically more powerful HoloLens model in the current form factor, or at least a more compact one capable of all the same (assuming the optics were also compacted) for revision 2?

There's a whole ton of stuff I'm not taking into account such as the physical size of the current HPU, but my guess is that this is the largest point of improvement just going by the process alone.
Not condoning this behavior at all, but don't we see this with the lack of equal access to drugs all the time? :(
Interesting that the article is almost a section by section copy of his Wikipedia page.

https://en.wikipedia.org/wiki/Carlos_Kaiser_(footballer)
True, but the longer we have to sit on our asses, the more likely we are to succeed in our effort to make a difference when we finally get around to it (due to technological progression).
Three companies tried and failed?

It sounds like it's harder than we might think to make this work.

Given that, and the low volumes, it might not be that profitable even at $600 per sale.
No it doesn't. Switzerland has one of the best healthcare systems in the world, which is completely private (although there are some public hospitals), but heavily regulated.
Ask HN: What's the name of that company that makes an AI that builds apps?
You can name any you know!

Thanks :)
Other companies don't sell them. They bailed for various reasons, and the expense of getting in just isn't worth it.

If you develop an EpiPen and it costs you a bunch of money then in theory you can make it up by selling more volume. Except your competitor can just cut the price because they are already selling for an absurd amount of money, so how do you win now?

Maybe we should have a non-profit that does generic versions, and we can subsidize it by preferring them to companies like this (e.g. all medicare provided drugs now go through this company which sells generics). Unless the companies are willing to match prices.
To all the folks in this thread suggesting 3D printing and all sorts of other ideas, keep in mind that Sanofi is not some fly-by-night or scrappy startup. They are a major pharmaceutical company with decades of experience manufacturing pharmaceuticals and the quality control that is required and even they couldn't get it right.

They actually had a very innovative product. It was much smaller than the EpiPen and used voice prompts to tell you how to administer the drug (people in the heat of the moment sometimes don't remember to leave the EpiPen in long enough for a proper dose to be fully administered). I'm frankly mystified how they botched things so badly that they had to pull the product.
tldr: STEEL SCREWS AND BOLTS are classified in Chapter 73, Harmonized Tariff
Schedule of the United States (HTSUS) under heading 7318. The tariff has separate
provisions for the different types of screws and bolts, and separate provisions for
threaded and non-threaded fasteners. The tariff pages covering the various types of
steel screws and bolts can be found by checking the latest version of the HTSUS at
www.usitc.gov.
The Knapsack Problem
It's kind of amazing that humanity's overall response can be summed up in a gif.

https://media.giphy.com/media/z9AUvhAEiXOqA/giphy.gif
An investor with low funding costs and stable funding source can always beat the market in theory. Studies suggest that the bulk of BRKs excess returns are due to leverage and deep balance sheets that allows him to buy deep value but more importantly to be able to hold those stocks long term.

A smaller investor who tried to duplicate that strategy would have been stopped out due to margin calls. For example it isn't everyone that can sell, and hold, a ten year billion dollar put on the S&P 500 like BRK did in 2008.
In this particular case the application was already quite POSIX-dependent in other ways, but it's a good point to make -- I did hesitate before deciding on it for that reason, now that you remind me.

To add additional details, for those who might draw amusement and/or wisdom: In all cases the input/output date/time strings had the same format. Further, a number of the bugs were due to half-implemented reinventions of atoi being involved -- and atoi was definitely available, as one of the reinventions used it! Finally, in at least one case there was a Y2100 problem.
Yes; this is why using the free market to set prices in health care is always such a troubling thing. People don't like the idea of putting a price on their health.
I'm sure the FDA could be more efficient, but isn't a large part of the difficulty intrinsic to bringing a safe and effective device to the market? The flip side of people dying from not having an Epipen is people dying because their generic Epipen didn't work.
How I Beat Procrastination to Launch a Side Project
This makes me want to buy one to replace my ADT-1...which is not easy to do these days.

I sure hope there is a future for standalone Android TV boxes that aren't as expensive and large as the Shield.
> Nobody knows about PAUSE frames until they bite you.

I'll be an exception to that rule. I first heard about them when trying to optimize point-to-point 10GbE NIC throughput. I worked with the support team from the NIC manufacturer because I was trying to saturate four ports simultaneously (at the time that was a big deal, it's probably much easier now).

I knew a good deal about them before I was ever "bit" by them.
> so how is this insurance company getting away with what they're doing?

It's not the insurance company, it's the drug company. The insurance companies are probably livid about the extra costs they're having to cover.

The answer to "how" is a variety of different techniques, including changing the formulation slightly (http://www.nytimes.com/2014/09/16/business/new-york-files-an...) and outright bribery of competitors (https://www.washingtonpost.com/opinions/pay-to-delay-pharmac...).
So is it the Year of IPv6 yet?

I've been hearing about this going mainstream for 13 years. I've been setting up servers to be dual homed with both IPv4 and IPv6 for years but so many people/companies don't even bother adding the IPv6 addresses as AAAA records in their DNS even when the servers support it.

But it's here. Exciting!
This is literally insane. I've never heard of a neural net branch predictor.

Edit: my layman knowledge about branch prediction and neural networks is showing its gross inadequacy :/
It would be very interesting to know where the layoffs were -- tech, marketing, course development etc.

(1) It would help us understand the significance of the move, (2) it would allow us to (wrongly) opine on the wisdom of the cuts, and (3) it would let us understand where they are in the lifecycle.
Of course. This case is particularly interesting because the device/drug combo is so commonly needed. But you'll find many other stories of manufacturers hiking the price of drugs people need to live, and the resulting backlash. Look up Martin Shkreli for a couple of recent examples that got attention.
How small to become profitable? You'll see, this ends in a no win situation fast. Sadly enough.
Same way Pewdiepie gets excellent YouTube customer service: he has millions invested in Google properties. Google's great at helping their huge money-makers, it's the literally everybody else who gets screwed by their awful robot systems.
IMHO, it would be better if you use a different domain with a cheap theme. You can even use both or many more in the same $5 VPS.
Well, if I can print 3 of them for 1/100th the price of a single one from said manufacturer, if the design is even adequate I'm probably still better off.
Mascara–Best 3D Fiber Lash Mascara Set
Can someone say "trading spaces" qoute
Because there's no equivalent of the bioequivalence study that generic drugs go through. Even if it's an exact copy, making a generic medical device means you have to go through the same entire approval process that the original went through.
The workers ("staffed") in the FDA are (mostly, probably) people who want to help but the bureaucrats in charge are part of the political system (e.g. lobbyists, political insiders, etc.). I think you're conflating the workers of the FDA with the people who, ultimately, guide it and make decisions.

This isn't to say the leadership of the FDA is compromised by or somehow beholden to "Big Pharma" or some such. I certainly wouldn't disagree that we need rigorous demonstrations of efficacy and safety for medicines and devices, but I question in what manner and capacity the FDA is actually structured to pursue that end.
I believe I have received a IPv6 address from a tethered LG G3 with T-Mobile. Have not tested with a tethered iPhone or paid attention in a while.
But that R&D was spent years ago.
Heavily regulated to avoid the corrosive effect of the profit motive?

You two might actually agree.
I like how this just isn't even coming to several states.
I have no evidence, but this headline coupled with the insulin price hike... it really feels like this is an attempt to manufacture a crisis.

I fill a prescription for epi-pens once a year (nut allergies), but insurance bears the brunt of the cost.
I've seen those. This idea would be different then that. Someone commented another site that looks like it might be actual competing site though.
It feels like they have an entire company of Mr. Spocks without a single Doctor McCoy to round things out.
I meant for a new entrant.
Illustrative usage examples for Terabyte
Weird! It doesn't seem like a particularly complicated device. Is anything publicly known about what was going wrong?
The numbers are right. If you want to compare to your own data you need to filter for users from the big four US mobile providers like mentioned in the post.
California Labor Code Section 2870 in light of forced arbitration agreements
Would it ever be possible for an employer to use a forced arbitration agreement to resolve a dispute regarding the employee's claim on IP that would otherwise qualify as a non-assignable invention?
I'm a huge fan of this kind of programming! While not using the Web Audio API, I built a DSL in Ruby that allows you to sequence an analog synth (or anything that speaks MIDI): https://github.com/tubbo/mass

I'm also working on a synth that models a Moog Voyager called "Worf: Son of Moog".
e: was wrong about everything
Nah because it would upset the free market.

I mentioned in another comment when someone from Europe or Canada asked something to the effect of "how come everything has to be free market in US even healthcare and such".

And I think the answer is we treat free market as a religion. We don't evaluate what is better, healthier, more rational answer for a problem. Like say, "How do we keep people from dying from anaphylaxis?" We don't answer that. We always answer first, what would free market want? Will it want us to do this? If not, we don't proceed.

We treat it as if it is deity of sorts and if we disobey we'll be punished.

Someone replied and said this idea isn't so outrageous because a similar concept has been defined already in politics:

American Civil Religion (https://en.wikipedia.org/wiki/American_civil_religion)

I am just proposing there is a similar religion in respect to free market.

It is often sold in propaganda terms of course -- we are not communists here, we just want efficiency, we want progress, don't worry stuff will trickle down eventually and so on. So we make it palatable but the main incentive is worshiping the deity.

It sounds crazy but evaluating a lot of things we do as a society through that perspective can be interesting.
If you have something concrete to say then say it. You're only lowering the quality of the conversation by making vague assertions in the style of "one weird trick" followed by mystery links to random places on the web.
This is probably going to get buried now, but in case you come back to this thread, thanks for pointing me toward "Listen, Liberal." Checking it out now -- I read Thomas Frank in The Nation every week, but I didn't know about this one.
Of course competing is part of life. I don't conflate that with it being the existential meaning of my existence. Sneezing is part of life whether you like it or not. Is life just one big sneeze?
The most obvious reason is just casually glancing around my office there's two PCs, two Macs, and two phones. Any of them could be in use at a time, and often the only thing that makes this convenient is having them all access the same data on a server somewhere.

Also, I can't lose data on a server if my personal equipment is stolen, damaged, or has a catastrophic hardware or filesystem issue (like hit my Mac a couple months ago). Odds are the server is running much better hardware than I can afford, with much better redundancies.
> In VisualWorks, there were different two ways of writing a short script to verify this in a matter of seconds.

This doesn't scale to either large programs or programs not entirely written by yourself.

In ML, there's no need to search anything: the only admissible operations on a value are those sanctioned by its type.

> You could also sometimes achieve this with a few cascaded searches through the Refactoring Browser.

As a library author, you can't search code written by users of your library.

In ML, I can prove things not only about my own code, but also about how others may use it.
Considering that virtually every plugin for Drupal is available on drupal.org, for free, and that all drupal modules are released under the GPL, I think you're going to have a hard time including Drupal in this. Not to mention you'd likely not even get to use the Drupal trademark without Dries' approval, and I strongly doubt this is the kind of thing that would get that approval.
Yup. I was about to arc up with an Amazon AWS rant until I read that almost-last-sentence. Headline is misleading, article doesn't ever really clarify, just throws that hint in at the end...

(I've got precisely zero mobile apps in the AppStore or Google Play that use IPv6 to talk to their backends...)
This seems less damming to me considering the medicine naturally occurs inside your body. What reason is there that nobody else can make a competing product for cheaper?