skysight-inc/HackerNews huggingface dataset:
> My patent lawyer told me to, but generally no

I am not a lawyer, but in my understanding, once you file, you have a priority date.

I hold an Australian patent with a US one pending. Both trace their priority back to 2012, when I made an initial filing through WIPO.

For each national patent granted, my patent coverage is backdated to 2012.

Either your idea is patentable, in which case, you might as well brag. Or it's not, in which case, you might as well pretend to brag.
I mean.... I do plan on looking at the 10-K to form an objective opinion about it

There's really almost no scenario where I'm going to say "yeah I don't want to be in a position to make a downpayment on a house by analyzing and pursuing that profitable scenario"

whether long, short, no play, I'll take a look

how about you?
Full PDF:
http://science.sciencemag.org/content/sci/353/6301/819.full....

This paper is cool because they've optimized the E. coli genome to entirely eliminate certain codons, which would, for example, prohibit infection by viruses that depend on particular codons. It also frees up codons for other usage, including novel tRNA complexes. The paper mentions the authors have validated 55 recoded segments of 50kb each. At ~$0.10/bp that would cost $577,500 for the DNA alone, though the authors likely paid less or synthesized the fragments in-house.

This is somewhat related to codon optimization, which is typically employed when genes are added to an organism to enhance expression, since codon usage bias[1] varies by host organism. If you modify an inserted gene so its codons match the dominant synonymous tRNA present, you'll see higher expression of the gene product. If you're engineering E. coli to produce insulin, your bioreactor will produce more of it for a given amount of feedstock.

1. https://en.wikipedia.org/wiki/Codon_usage_bias
It's 100.000 records first month and you can request to extend it. What do you suggest we do?
I love his videos. My girlfriend thinks I am a complete nut because the first time I watched this video 'Functional programming design patterns' (https://vimeo.com/113588389) I was crying with laughter. She just couldn't understand.
Forgiveness is up to you.

I'd prefer the criminal justice system focus on rehabilitation rather than punishment. I'd rather we try to make society safer than exact revenge: we all have different ideas of revenge, but a safer society ought to be pretty easy to agree on.
You seem to still be confusing the concept of free speech with the legal enshrinement as such. They are different. One is a philosophical idea, and one is a legal protection. I understand they often are muddied, since it's usually governments coming for your right to voice your thoughts, but it is not de facto a government issue.

Nobody is arguing it's illegal, or they should be punished by the government (no one sensible anyway, if we're going to pick the worst arguments / representatives from the different sides of the issue, it's going to be a long day. Also, don't argue with those people). People are just arguing about free speech violations as a philosophical idea.

Further, given the influence corporations wield, particularly in the dissemination of information, this is an important discussion to have. At the risk of being a super nerd, look at the setting for the tabletop RPG Shadowrun to get some idea of a plausible (though extreme) outcome for corporations in the US (ignore the trolls and magic, unless you're into that). I tend to err towards more freedom, and letting Twitter do what they want, but that doesn't mean the implications of their actions shouldn't be discussed.

edit I can't reply to the message below, so I'll do it here. It sounds like we're probably pretty closely aligned philosophically (I think they can do what they want but people should be able to see what they're doing to better decide if they're on board). My issue was with your original comment that appeared to mix the legal with the moral. Beyond that, we're cool :)
Thanks for the suggestion! I'll check it out.
I think it's fair to say that the greatest cloud risk isn't actively and persistently hostile providers - mostly because that sounds like an almost hopeless task.

Definitely agree. I know we like our security systems impervious to anyone and everyone, be they script kiddie or the entire NSA. However if you hand your machine over to someone else to run, (in either VM guest or box form), I think you need to acknowledge that you are incontrovertibly accepting slight vulnerability to the colo/VM host.
I completely agree. And considering forgiveness is such a core tenant of Christianity, it's surprising that people call the U.S. a Christian nation. Our use of capital punishment is also bizarre when you factor in the religious component. Or the utter lack of care for the poor.

And I'm not saying religion should influence our laws, but I find the hypocrisy astounding when the far right in this country is hell-bent on pushing their religious beliefs into our laws and government policies (abortion, birth control, marriage, etc).
Housing Refugees Could Be as Easy as Tweaking Airbnb
>And the most accurate part of the movie was that it showed the anguish that each of these people went through. They'd seen something no one else had, been right about it, had the event happen and even then everyone else continued to plug their ears and pretend nothing was going on while they continued to bleed money each month. It really did a good job of showing that you can be right about everything and still not make money if the rest of the market continues to act insane.

You mean: it showed the part where the assholes had grabbed control of the government and rigged the market, pointing a gun to the head of the world economy, so that their idiotic bets would pay out by force, thus penalizing everyone who had bet on the facts, right?
Any specific reason for using Homebrew? Rustup [1] works great.

https://www.rustup.rs
Scientists uncover origin high-temperature superconductivity
> No, an appeal to authority is when you say that because someone is an authority in one area, they should be listened to in another.

It's really not.
very dark yet very accurate
Is Hillary's support for mass surveillance really "optimistic"?
The key is only useful if you have something to unlock. The web is responsible for the extreme number of users we see today, and it was invented by a British guy. The funding came from an European laboratory.
Hilariously, he was a Policeman for 30 years :)
https://github.com/rust-lang/rust/issues/35807
We've been hearing about rate hikes Real Soon Now for more than a year now. Have they actually happened? I haven't heard of any.
I would agree that Windows is nowhere near being on life support but I do think that the size of the desktop OS market is shrinking and that in the future we may see a lot more home computer users move to tablet only or something like a Chromebook.

Enterprise users are much more slow to move but as enterprise SaaS offerings become more robust we may see a lot more businesses move towards a thin-client (a la ChromeOS) and SaaS model to meet their needs. Microsoft is doing the right thing by quickly getting out in front with Office 365. If they hadn't maybe something like Quip or Google Docs could have starting stealing significant market shared but now I don't think many enterprises would bother switching if they can stay with Microsoft.
Hey newfriend, let me remind you of rule #1 and especially rule #2.
Thanks for that - I suppose, I would only say that your analogy might be tweaked a bit. It wasn't so much that they replaced y with i as "however" with but.
There are definitely elements of the fire service that are - for better or worse - "this is the way it's always been done".

In some ways it works. It doesn't noticeably change your efforts or effectiveness, just your tactics, and now you don't need to question "is this a feature of this car?". Just like "what cars use extensive magnesium in the engine block?" or "does this vehicle have airbags? did they deploy? how about side airbags?" Just assume they do, and use a commonality of technique.

There's definitely a challenge between reconciling techniques that work in the field and textbook operations, and then keeping both up to date with the latest 'discoveries' - for instance forty years ago many fires were contained by a lack of fuel, nowadays it's a lack of oxygen (better sealing, even with ventilation systems) and higher fuel loads (petrochemicals in homes and furniture) mean that oftentimes by the time we get on scene you can have this home that is a darkened down box, thick black smoke with little or no visible flame, hotter than anything, and as soon as you open a door, you have about 90 seconds to get some cooling applied, or you're going to have flash over by virtue of all the oxygen you just supplied to this nascent fire.
It was pretty easy for Iceland to tell the banks to fuck off when it was mostly British people who were losing their life savings, not Icelanders.
So the government shouldn't only be deciding who can or can't lobby on a particular issue, but which side of the debate each respective party can or can't be on? "I'm sorry sir, but given your circumstances you may only support these Approved Beliefs."
"An OS for the cloud" is actually fairly descriptive. Sandstorm is both a set of
It's not politically charged at all. It was about technological diversity. Did you even read the article?

APIs and a distro for serving webapps based on those APIs. If you use Sandstorm, they claim your webapp will be easier to distribute, serve, and create. All of this was said clearly on the site's main page.
Yes, the economic burden but also the ethical burden of ensuring their sentence is administered fairly. Corporeal punishment at the hands of the guards is not a fair administration of the punishment.
What does that even mean, to "ban lobbying"? You can't approach legislators and advocate for legislation?
Probably because those are normal mathematical operations to convert between different units of measurement for the same abstract thing in math.
I don't want to derail you too much, but I'd argue that Twitter should just be open about what editorial decisions they've made (they don't have to justify it if they don't want). Then people can decide whether they like it or not. People just need a means of evaluating the implicit bias of the organization as you can do by looking at the content of a newspaper. When things just disappear without the reader having a way of knowing, that's when it becomes a problem, to me anyway. Granted, things just disappearing is a problem with newspapers these days too (at least online).
That was indeed the idea. Sit alone in your cell, read your bible and pray to become a better person.
> What free services are you using that aren't ad supported?

Personally I use Flightradar24, Weather Underground, Shipfinder and some other lesser-known networks for free without ads because I feed data to them. They even give me ad-free phone apps.
I did just that now. Wasn't even aware of it. Main page of Rust offered me pkg only.
Also, methods can be called with a function-like syntax, if you prefer:

let r = f32::to_radians(5.0);

let x: f32 = 5.0;
let r = x.to_radians();
It uses EasyList as well, the shared block list.
> I find the hypocrisy astounding when the far right in this country is hell-bent on pushing their religious beliefs into our laws and government policies (abortion, birth control, marriage, etc).

While I have met many Christians in America that do live by their beliefs, I have found the majority of these self-professed "Christians" I have met are simply using the term as a tribal banner in which to wage a cultural war that enriches them and continues their evolutionary propagation at the expense of those that are not of the typical WASP voting bloc. The Christian doctrine of acceptance and tolerance appears long lost, and this same bigoted crowd often seems to be those that wonder why it is many people have turned to secularism.

Those wishing extreme "punishment" on those we incarcerate -- and are supposed to rehabilitate -- are wishing to play the role of the God of the Old Testament, not follow the teachings of their messiah.
Unhosted.org pioneered this already years ago. As did pagekite.
Canvas Everywhere (Canvas for iOS)
Pool Maker Responds to Rio Pool Defect Claims
> By using mmap and toggling the register directly from a C++ program, the GPIO can be toggled at about 2.8 MHz, much faster than the device driver approach.

I mean, it doesn't need to be C++. I was getting pretty close to that speed with the same strategy (mmap the registers directly) with a python library I wrote. It's not exactly pretty, and was the first semi-major python project I was working on, but it was fairly functional.[1] If I remember right (it was quite a while ago), I was routinely seeing speeds around 1MHz. BUT you'll occasionally see hiccups of as much as tenths of a second, because Linux is decidedly not real-time.

I ran into a pretty tall brick wall when I started trying to do pin muxing[2] using the same strategy. Going pretty far down this path lead me to the conclusion that the best strategy for boards like BB/RazPi is to run them on an exokernel and then have per-language libraries that access the registers, with the exokernel[3] enforcing memory access rules. You could even use that library on multiple platforms by declaring the memory mapping for the registers as, for example, a json schema. All of the systems on a chip that I looked at datasheets for while I was working on that project (which was admittedly an extremely limited sample size) go through the same strategy of fixed physical memory addresses for peripheral pins.

[1] https://github.com/Badg/hwiopy
[2] Pinmuxing is the process of switching functions for a given pin. Basically, SoC's are so small that the chip designers will put more than one thing, say USB + GPIO + HDMI, on the same pin. Muxing -- which is ultimately also controlled by a fixed physical register -- switches between modes. Muxing is only available from code running in protected mode, and besides, Linux wets the bed if you try to do this at runtime. That may sound silly -- why would I want to switch between USB and HDMI at runtime -- until you either think of other examples (for example, GPIO vs analog in), or realize how much of a pain in the ass it makes it to do a bunch of operating system modifications just to reconfigure your pinout. Basically, it makes development an enormous pain in the ass.
[3] Exokernels are really cool, basically the lowest level of abstraction you could put in a kernel: it promises not to let you fuck up the hardware, and provides some very basic abstractions, but otherwise just gives you free reign. Very much the "consenting adults" strategy. https://en.wikipedia.org/wiki/Exokernel
Yes and no.

They contribute more to the tax because they are bigger, more powerful, potentially less efficient.

They have to pay for weight because the increased weight has a direct correlation in actively shortening the life of the road, above and beyond "vehicle-miles covered".
In that case the insurer should do their due diligence before taking the bet.
Not true; they are quite correct characterizations.

In theory, union officials are elected by the members of the union. In practice, union officials are elected by the members of the union. In theory, the head of a corporation is the head of a corporation and may do whatever he likes so long as he and a small cabal of directors wish. In practice, the very few executives at the top of a large corporation run it like a dictatorship, and they primarily serve their own interests -- not the interests of the employees or the shareholders. And even when they do act in the interest of shareholders, that's simply a code word for "a tiny group of wealthy elites" -- shareholders are wealth holders, so invariably even the most honest and earnest CEO will be acting in the interest of large amounts of wealth (oligarchy), not large amounts of people (democracy).
Yes, rustup.rs is still technically in beta. We will make it the official, recommended way when it's ready.

(I've been using it daily for months and it works well for me)
Sorry, I seem to have misunderstood a crucial part of what you were saying, which is: using the data as evidence in court. I also dug around to see if the FBI has any surveillance apparatus like what the NSA is doing and didn't come up with anything credible in the few minutes I looked. They appear capable, but, as of yet, have not started that anyone knows of.
While we're wondering why some sports fare better than others, anyone want to lay odds on the long-term survival chances of the wild and wacky game of Buzkashi? It's the sport where your team, on horseback, tries to get the goat carcass into your opponent's goal.

https://en.wikipedia.org/wiki/Buzkashi
So the people who ship via trucks are all going to go out of business because they just can't see how much economically better trains are?
I think the mindset is valid but the people behind it are inconsistent, if your locale is being around indignous african people. Then killing and enslaving them kinda goes against the whole "act local" thing.

Thereby making them immoral by their own standards.
You cannot export your sense of locality to somewhere else, i dont think thats how it works.
Hmm, https://www.youtube.com/watch?v=NhheiPTdZCw anyone?

(Finish the video before replying.)
Even Olympics officials have said the conduct of the Brazilian fans is unacceptable. If you're not just trolling you can search out some quotes yourself.
A Bot that Calculates your quarterly taxes?
And Iran cuts thieves hands off with band saw.[0] What's your point? Barbarism "works"? No thanks.

[0] http://www.telegraph.co.uk/news/worldnews/middleeast/iran/98...
The initial release is an “alpha” and is community supported. In the future, we will deliver an official Microsoft released version of PowerShell based on open source to anyone running a supported version of Windows or nix. The timing of the official Microsoft version will be based upon community input and business needs. We hope all of you will help us get it right!

'Based on business needs' = if there's ever enough demand.

Still, pretty cool.
The Phishing Epidemic
...makes people no longer expect themselves to spend even 5 seconds of learning to master a tool.

I, too, lament the state of user education in the computing world, but you can't change what people want by giving them an alternative that's technically superior, yet more difficult to set up.

Again, I point to Dropbox. You can most of the way there with some simple scripts and coreutils, but for some reason, my gran wasn't using this until someone wrapped it up in a nice UI and abstracted the complexity away. For some reason, she uses the Gmail web client instead of Mutt, even though the latter is objectively faster and more productive. For some reason, she uses a feature phone instead of a smartphone, even though the latter is easy to use and can do so much more.

There's a lesson here, often lost on more technical audiences, and I think it's this: Time and interest is limited, and developers should respect user's time and preference more than they do now.
https://en.wikipedia.org/wiki/Otto_GmbH
There is a big difference between profiting from people versus profiting indirectly through supplies that a public prison uses.

The incentives are totally backwards. The state should be encouraging people to not be in prison, but instead we have monetary incentives in place for putting more people in prison and keeping them there.
These are my cousins. I disagree with this characterization of our ball game. It's a racist interpretation by ignorant white anthropologists who simply publish sensationalist nonsense with no understanding, nor desire for understanding.
Wow that modern CSS making it difficult to read longer than 2 seconds.
If your running relatively recent kernels on the board there's now a character device interface for gpios: https://patchwork.ozlabs.org/patch/580307/
Please make me go viral
this is a good song , its just we don't have the right people support it
https://i.ytimg.com/vi/8INSQpWeK-g/hqdefault.jpg?custom=true...
yes, they would. in a couple election cycles they'll have their own people running the agency

and then that generation of newly politically-aware young adults will have to tackle that

I think its a pursuable solution to address today's problem to get a better reflection of what American people want
I find her stance on prisons hard to believe considering her comments[0] as first lady. You might believe she changed but it shows a massive error in judgement at very least.

[0]http://m.youtube.com/watch?v=8k4nmRZx9nc
Homeownership was a major pillar of post-WW2 cultural stability among the middle class, so subsidizing it was considered a social good.
Scrivener is a one-stop shop for this sort of work. Ulysses might also be sufficient. The learning curve for Scrivener is fairly steep, though, by comparison.
Shouldn't to_degrees and to_radians be part of a trait that f32 and f64 (and potentially other types) both implement, rather than being independent methods directly on f32 and f64?
Maybe close enough:
http://spectrum.ieee.org/automaton/robotics/robotics-softwar...
You're right it would be totally worth all the walking and bromancing.
Not the case that the employees do well as the company does well. The company does great when factories are closed and replaced with slave labor overseas. The employees, not so much. The company does great when its employees are forced to train their H1B replacements who are held hostage by their visas for no wages and then fired. The employees?

The company does great when it pays its employees the smallest amount possible, gives them the least benefits, since every cent of extraneous labor cost is, by definition, extraneous lost profit.
We're still pretty far from being able to produce an AGI that even has the learning ability and self-preservation instincts of a horse.
Perfect is the enemy of the good.
He should know: he's probably the individual with the single largest share of responsibility for the housing crisis.

Not to mention responsibility for setting up with swindle that is currently used as an excuse by those who want to feed Social Security to the ibankers.
The problem with native desktop Java applications that although Swing is quite powerful, it requires developers to go through books like "Filthy Rich Clients"[0] to really take advantage of it. Which very few do.

To this day I still meet developers that aren't aware how to change the default L&F to native widgets, for example.

Whereas Windows Forms and WPF already provide a much easier out of the box experience, and have tooling like Blend available.

I am curious what the JavaFX sessions at JavaONE will cover.

[0] http://filthyrichclients.org/
Windows users will no longer be able to apply individual patches
Funny enough, I was recently working with a startup that wanted to buy the ot.to domain. It looked like it was being used for directions to an event or someone's house no longer than a month ago.

We were also thinking of branding as Otto, and had a hard time finding anything about a company named Otto -- stealth mode indeed.
yeah. I read a the article and nothing about it seemed compelling. I got bored within 30 seconds. Therefore I see a bunch of 2014-era tech dreamers who have no clue that to bootstrap a business, you better have a hard pitch about a specific and clear service. Especially now that money is drying up. Cute cats don't cut it anymore, and neither does philosophizing.