One of my favorite early scenes from Makers by Cory Doctorow comes to mind. (For context, Lester had just brought a homeless woman a doggie bag from Denny's, where they were about to get breakfast).

> Lester joined them again. He was laughing. "She is funny," he said. "Kept hefting the sack and saying, 'Christ what those bastards put on a plate, no wonder this country's so goddamned fat!'" Perry laughed, too. Suzanne chuckled nervously and looked away.

> He slid into the booth next to her and put a hand on her shoulder. "It's OK. I'm a guy who weighs nearly 400 pounds. I know I'm a big, fat guy. If I was sensitive about it, I couldn't last ten minutes. I'm not proud of being as big as I am, but I'm not ashamed either. I'm OK with it."

> "You wouldn't lose weight if you could?"

> "Sure, why not? But I've concluded it's not an option anymore. I was always a fat kid, and so I never got good at sports, never got that habit. Now I've got this huge deficit when I sit down to exercise, because I'm lugging around all this lard. Can't run more than a few steps. Walking's about it. Couldn't join a pick-up game of baseball or get out on the tennis court. I never learned to cook, either, though I suppose I could. But mostly I eat out, and I try to order sensibly, but just look at the crap they feed us at the places we can get to -- there aren't any health food restaurants in the strip malls. Look at this menu," he said, tapping a pornographic glossy picture of a stack of glistening waffles oozing with some kind of high-fructose lube. "Caramel pancakes with whipped cream, maple syrup and canned strawberries. When I was a kid, we called that candy. These people will sell you an eight dollar, 18 ounce plate of candy with a side of sausage, eggs, biscuits, bacon and a pint of orange juice. Even if you order this stuff and eat a third of it, a quarter of it, that's probably too much, and when you've got a lot of food in front of you, it's pretty hard to know when to stop."

> Suzanne couldn’t help it; she blurted out: "But willpower --"

> "Sure, will-power. Will-power nothing. The thing is, when three quarters of America are obese, when half are dangerously obese, like me, years off our lives from all the fat -- that tells you that this isn't a will-power problem. We didn't get less willful in the last fifty years. Might as well say that all those people who died of the plague lacked the will-power to keep their houses free of rats. Fat isn't moral, it's epidemiological. There are a small number of people, a tiny minority, whose genes are short-circuited in a way that makes them less prone to retaining nutrients. That's a maladaptive trait through most of human history -- burning unnecessary calories when you've got to chase down an antelope to get more, that's no way to live long enough to pass on your genes! So you and Perry over here with your little skinny selves, able to pack away transfats and high-fructose corn-syrup and a pound of candy for breakfast at the IHOP, you're not doing this on will-power -- you're doing it by expressing the somatotype of a recessive, counter-survival gene.

> "Would I like to be thinner? Sure. But I'm not gonna let the fact that I'm genetically better suited to famine than feast get to me. Speaking of, let's eat. Tony, c'mere, buddy. I want a plate of candy!" He was smiling, and brave, and at that moment, Suzanne thought that she could get a crush on this guy, this big, smart, talented, funny, lovable guy. Then reality snapped back and she saw him as he was, sexless, lumpy, almost grotesque. The overlay of his, what, his inner beauty on that exterior, it disoriented her. She looked back over her notes.