skysight-inc/HackerNews huggingface dataset:
Yes those drugs. Hard to say conclusively, but the failure of most of CETP inhibitors is troubling news for the hyperlipidemia theory. Meaning possible hyperlipidemia has multiple causes and in and of itself isn't bad.

AKA

Cause A results in hyperlipidemia.

Cause B results in hyperlipidemia.

Cause C results in hyperlipidemia and arterial plaques.

Cause D results in hyperlipidemia.
Great stuff! How did you build the community around NomadList early on?
I have no idea is a muscle memory thing :-)
The J kinda looks like an arrow pointing down. If you squint.
Most concurrency models work if you understand both your problem domain and your tools thoroughly, and fail if you don't. Event-driven callback spaghetti, for all of its flaws, has been used successfully in services with billions of simultaneous users.

OP was asking for ways to broaden his concurrency knowledge, and studying message-passing, transactional models, promises, etc. will certainly do that.
I built the site, but then I thought, omg I'm going to lose all these users once they leave.

So I added a MailChimp email box, then a chat group, a forum and kept making more for them. That's how people kept coming back and finally paying money.
Fresh grads. Entry-level SWE.
Other sources of lead, such as paint, are still an epidemic in poor neighborhoods. I wonder how much of an impact it's having, and if there's a measurable correlation with the age of houses and violent crime.
I use NoScript for security reasons. I find that I usually only have to turn on 1 or 2 scripts to get the content on the site to show. If even that as many show it without scripts. It's a tiny percentage, often using fancy crap underneath, that absolutely require JavaScript to even see static content. I don't loose much ignoring them but gain plenty in security, loading speed, and battery savings.
I think it is more the fact that he is a single founder (and one man band by the sounds of it) that s/he wants to hide. Business customers are not happy to buy from a business with a single person risk.

Personally in this market having a business run by a single person is probably these risky than a small team since the chance of bankruptcy is less.
> spread of Fear, Uncertainty and Doubt

I agree with your comment but, what's with the capitalization of these words?
Police scanner laws seem really antiquated.

Would a smartphone with a police scanner app (or even just TuneIn) count?

Encryption is the correct solution anyway.
There is no reason to believe it is even possible to even create such a God-like intelligence. Even harnessing the energy of the sun would not give you enough energy to compute anything about the universe. We also have every reason to believe that even if this were possible, it would only happen in the far future (e.g. hundreds of years).
> Or even Go

lol. Felix has Sum types, meta types, pattern matching, algebric types, unions , sets, records, channels ... Go has what? a rigid type system and channels ...
Ha thanks :)
Your question could definitely have been more neutral. I think most people read it as you trying to invalidate the article.
I've actually been working on a new email client, and a terminal one at that. Shameless plug: https://github.com/SirCmpwn/aerc
please, can you tell us more about working remotely as a developer out of tunisia? great to hear exporting businesses are tax exempt. how is the internet connectivity?
Dell UP3017Q 4k OLED 30-inch Ultra HD Monitor $4999
This is great! Nice work. I will be bookmarking this. Cheers.
The article didn't really sell that arrows have an advantage over monads as far as callbacks are concerned.
It's probably more beneficial for evolutionary 'creativity' than the complex pathways in biology you depend on; and that's gotta be the only reason a quirk like that is still around.
The Jack Flack Interview with a Spokesman (2015)
Well, the academic and implementation-wise freedoms are huge compared to any SV startup. And you don't need to worry much about financials, nor marketing, nor a million other things that many hackers dislike.
I would imagine a global smoking increase statistic would be per-capita as well but without a citation we won't know.
> SF(go Giants & Warriors!)

The Warriors are in Oakland (for now)!
I tried an android for a couple of weeks recently, I tried it using the "Oneplus 3" as it was good bang-for-buck and ran the latest software with plenty of grunt. Hardware wise the unit is lovely, not as high build quality as my iPhone 6s+ but not nearly as bad as the Samsung Galaxy S3 I had tried in the past. The OS looked pretty... at first, then I started installing apps and it very quickly felt messy. I noted that the general 'quality' of android apps felt quite poor. Nothing seemed to integrate very well, if at all and a lot of apps felt like they hadn't been maintained for quite some time despite being the 'the best option' available.

I had a go at disconnecting my from the clutches of google first by trying not to sign into any of their applications and disabling all the information reporting in settings, I felt like y was a bit like how iOS was back in the iPhone 3G days when you had to root the phone to do half the things you wanted.

I then ended up flashing a custom rom that was pretty much stock, but without the good stock apps, I had to install the google App Store and create an account which I think is fair enough because I couldn't be bothered dropping custom downloaded apks and using that dreadful android transfer tool from my laptop which seems to work 4/5 times you plug your phone in, but like a lot of the apps in the ecosystem - felt very 'javaish' (pun slightly intended).

Anyway, I'm going to wait for Fedora or similar to becoming installable on the device then use it as a mini server / portable desktop because android just feels so fragmented and I can't help but feel like I can't trust the platform or the company that created it.

Hardware wise the OP3 felt like it was design with more care than any other Android phone I'd spent any fair amount of time, I love that it uses a USB-c port but was disappointed to find that it was actually only USB 2.0.
You're correct. It's even referred to as iVerge on reddit/r/Android (despite that sub being regularly trolled by the remaining Apple faithful).

That said, if you speak ill of Apple on HN, you should be prepared to be downvoted. The Apple zeal runs deep here.
The article indicates most of the lower disease rates are also in developed nations, so this could be indicative of a correlation.
Other factors, possibly:

- Signing a new lease costs a few thousand dollars (security deposit, possibly several months' rent, etc). Or transaction costs, if you're a home buyer. Americans across income levels are generally living paycheck-to-paycheck [0] and would need to scale down their standard of living for at least a few months to save enough money to move. It seems only elite jobs pay relocation expenses.

- Two-earner households are more common than in the 1970s; it's harder to find two new jobs than just one.

- People seem to be more concerned about school district quality, restricting the amount of housing supply seen as viable. (I made this one up, apologies if that's wrong).

- Homes are bigger (by nearly 2x) and presumably have more stuff in them as well [1], which increases the logistical difficulty and expense of moving.

[0] http://bigstory.ap.org/article/965e48ed609245539ed315f83e01b...

[1]https://www.aei.org/publication/todays-new-homes-are-1000-sq...
Another issue is that the areas with the strongest job markets (e.g. the bay area) have exorbitant housing costs, constraining people (especially those with kids or pets) from moving there, even if they'd be able to find a good fit job-wise.

Some of that is inherent; you're always going to have costlier housing in booming areas than ones that are economically depressed. But a lot of it, as has been discussed here before, is due to restrictive zoning laws that make it hard to match housing demand with housing supply.
I'd argue many of the cities in blue (extreme expansive/inexpensive) have culture at least on par with many of the most red/expensive/restricted cities -- it's different due to geography.

Austin, Atlanta, Las Vegas, Orlando compare favorably to San Jose, San Diego, Sacramento.
Its great that you can enjoy the "best-tasting eggs" but not everyone can afford the labor intensive organic eggs and grass-fed beef. There are a lot of people struggling to put food on the table as it is.
Oh for heavens sake. Why is it every time recession bites it's the poor bloody workers that need to get their rights curtailed, their notice periods chopped, their families spread over thousands of miles just to keep profits up.

Why can't the companies start flexing !

Why can't we have we have more most jobs as remote work, office jobs that don't demand 9-5. why can't they pay me more money for my "flexibility" - according to the article it's going to cost billions if I am not flexible, so give me some of that. And non-compete clauses - yeah don't make me laugh. Don't want me to compete with you. Pay me then!

Really almost all of these problems go away if the companies fork out gobs more cash for their workers, or start getting realistic with how the social contract has been ripped up so that the implied promise of cash in all the years to come has to be paid now. Learn to do NPV calculations for the salary in twenty years time you aren't going to pay me.

Workers need to move across country to get a job. Most people on HN could do their job from a different continent.

Companies in the Bay Area would stop competing for the brightest SF residents and have to compete with companies the world over.

I think that is the point - the labour market is the one market that has not (yes, not) been globalised yet. Almost all companies hire within thirty miles of the office doing the hiring.

Imagine if you could only get food, goods and services within a thirty mile radius. Globalisation seems to be working for other things - roll on the globalised labour market. Cough up boys.

Edit: added extra rant at no extra charge.
Sometimes a really pure batch appears, and the users' old dosage of impure/cut stuff is way too much. Quality control &consistent product isn't really high on importers' list of priorities.
Its typically abbreviated as FUD.

https://en.m.wikipedia.org/wiki/Fear,_uncertainty_and_doubt
NONSENSE.

autonomous cars are all gps enabled tracking devices which record every move your vehicle makes on 3rd party servers which double as government spying devices.

many people guard their privacy. it is enough that the computer and cell phone have made their impact.

there are many people who simply want to preserve their privacy and freedom of movement . while i do not necessarily sympathize with this view, it is not deniable that the future of technology development implicates far greater social issues than the past of simple technologies which replaced hard labor in simple situations.

a significant portion of people undersatnd these issues and that is why they are against self driving vehicles, NOT only because they want to drive their own vehicles.

if we are going to look at the future of technology, we have to look at the future of our entire system of government and society.

automated transportation is perhaps one of the most socially radical inventions of the first half the 21st century. 2nd only perhaps to quadcopter drones invading all technology applications.
If you're interested in personal DNA sequencing but don't want your genetic data shared (or you want to be able to analyze your entire genome, not just the small bit 23andMe does), check out Guardiome. This is their entire mission statement as a company.
Once again — why everyone needs to be in Bay Area to work productively? From the SF employers' perspective, if on the one side is "hire locally and pay exorbitant salaries to cover exorbitant costs of rent and everything else", and on the other is "hire remotely and get the best of both worlds", why the first option is ever chosen?
Are there lots of opportunities to work on static analysis and theorem proving outside academia, especially in Silicon Valley?
Whether you personally like them is irrelevant. It's an extremely popular service, and the company has a very high valuation.
And the privacy of my genetic data is not worth anything to those other parties, but it's sure worth something to me.
Happy to participate. You're welcome, whoever benefits.
A comment like this could be very insightful, but you didn't mention what h-pylori is, or why water treatments help reduce it.
> I am looking to move cities, but after factoring in an astronomical rise in housing cost, and a price of living adjustment that does come close to matching, I am having second thoughts. Why move to a city to do stuff, if once I get there I cannot afford to do anything.

There are a number of good, affordable cities. Baltimore is fantastic for how cheap it is.
Good points.

I've found something I can use to start with, older dumps of comments and stories that allow me to at least figure out which ones are the dead ones (because they're not in either set, so they are worth crawling individually, dead items are only a very small number compared to the rest).

That should get a base of about 7.5M items cataloged to test with, once I have that working I can use algolia per your suggestion to fill in the blanks.

Thank you very much for the suggestions!
Alan Greenspan wants the US to go back on the gold standard
Numerous lines of evidence, including randomized controlled trials, single gene studies, and Mendelian randomization studies, are not consistent with your interpretation.

Multiple agents that reduce cholesterol, including ezetemibe and statins, reduce cardiovascular disease outcomes and death.

Multiple cholesterol-related genes, including HMGCR, LDLR, APOB, PCSK9, and ANGPTL3, contain variants which influence both LDL cholesterol and the risk for coronary artery disease, myocardial infarction, and death.

And Mendelian randomization studies that rely upon a dose-response relationship between genes that influence cholesterol and the cardiovascular outcomes that they cause have also demonstrated a link between genetically driven cholesterol levels and hard endpoints.

So, one set of drugs (CETP inhibitors) that don't seem to follow the story are more likely to be the exception, rather than the rule. Interesting biology awaits us in the explanation of why the CETP inhibitors don't do what we imagined they would with hard outcomes.
I find readability times speed times expressiveness to be more important than any single feature.
Or maybe both.
"Look at nurses, they believe their income will be cut if we let in Filipinos and Indonesians"

That's obviously true isn't? If the intention is to import workers then clearly the supply of labor will increase which means wages will fall. When it's the rich advocating for their class interest (cheap labor and easy outsourcing) somehow they get away with claiming they're selfless. When it's the middle class advocating for itself apparently we call it "xenophobia".

What does Katsuyuki Yakushiji think about removing his tenure and exposing Japanese sociologists to cut-rate competition from the Philippines or Indonesia?
There are logistical issues to distributed teams. It can definitely work, but I think it's context dependent. It's not a panacea to high housing/labor costs; if it was, you'd already see the big tech giants like Google/Facebook/etc. predominately hiring in cheaper places, which they're not doing.
How to Gain Weight with a Fast Metabolism – 5 Easy Steps to Follow
“The code that took America to the moon was just published to GitHub()”
Put bluntly: All of these 'little increases" are starting to add up in big ways. I'm not that surprised that a decline in one disease is leading to declines in others. As we all live a little longer, we make each other healthier as well, being better able to cope with the expanded safety net.

As someone who's seen her grandparents suffer with a cacophony of diseases right before death? Sometimes, one thing really DOES lead to another.
Think about something that would be useful for you and bring you value. That will be something you enjoy building most.

For the portfolio portion maybe tie in something that would be valuable to your typical client.

That said here are some ideas:

Simple budget app to track/project your spending/decide on purchases/project income?

Track something you collect. Lego minifigures maybe or episodes you've watched of your favorite tv show.

Budget/Time estimating tool for work projects.

A real time chat app or social media app for you and your family and/or friends.

A 'dashboard' app for you and your family, share your locations, leave messages, simple to do lists, weather tie in some apis of services you all use.

Not sure what framework you use or are planning on learning.

I've been using Laravel for a couple of years now and have been using Vue js more and more. They are a great combo and auth comes together pretty much right out of the box.

https://laracasts.com/series/whats-new-in-laravel-5-2

Laravel has some great tools

Great documentation: laravel.com

local development made easy: Homestead (Virtual Box) and Valet (a new tool for OSX that creates a lightweight server that would be perfect for your project).

Build Servers and Deployment: forge.laravel.com (setups SSLs from dashboard through LetsEncrypt).

Envoyer if you need zero down time deployment.

Nice video tutorials at Laracasts.com

Enjoy your summer vacation and good luck building a cool app.
They left out home ownership. People own large houses, full of crap, with large mortgages, and since sellers must compete with new inventory, they have to stage their house, usually while living in them. With painting, upgrading materials and flooring, you can easily be looking at having to put $10K - $15K into a home to get top dollar back out. It's a daunting prospect, if you're working, have kids, and especially if you've done it once before.
global warming will kill us all.
Is it possible that medical advances in the last couple of decades have simply delayed the deaths of many sufferers? Heart disease and cancer survival rates are usually qualified with a number of years, given that they are difficult to fully cure. With a larger aging population just barely hanging on, perhaps an upswing is just around the corner but hard to see now. i.e. the rate of death has not actually dropped, the average survival time is longer.
Are you suggesting that some post-Nixonian mechanism is in play here.
77.1% white including white hispanics (speaking Spanish doesn't make you not white!) Source: same link as parent
I have yet to meet one single person who can logically explain to me why drugs should be 100% illegal. I've heard, "Would you want cocaine available at 7/11?" No, I don't want cocaine available at 7/11.

But if you can already buy any drug on the street, a doctor should be able to prescribe medicinal heroin to an addict and get them into the system to monitor them for treatment, with the end goal of getting them off of drugs. Putting unknown chemicals of varying strength and quality into their vein is what kills addicts. They do not typically OD because they are suicidal, it's because they unknowingly bought an extra strong stamp and then die.

I grew up in Massachusetts, and had a high school graduating class of around 300 people, and 6 people have died of overdoses in the last 10 years. One of the most popular girls in my class died a few months ago. I firmly believe that allowing her (and everyone else) to get her opioids prescribed would at the minimum keep her from overdosing, and let people who care know she has a problem. Dying on a toilet with a needle still in your arm is a terrible, useless way to die.
There is no tautology and no conflict. Both would be true statements of their conditional claims were true. The trouble is that internet advertising is far more likely to be overvalued than cars are. I think everyone in the thread knows this and is just being a bit difficult for some rhetorical purpose.
The GitHub page states: "The project is in alpha stage and was written in just a few hours taking code from my other two projects, load81 and linenoise."

https://github.com/antirez/kilo
Hippie Parody
The cool thing about the internet is there's a whole universe of information at your fingertips:
https://en.wikipedia.org/wiki/Helicobacter_pylori
You beat me to it. My guess would be increased time from those atmospheric nuke tests.

Those were crazy days! The Tsar Bomba. What was the world thinking?
Hackpad is teaming up with Dropbox
> I wouldn't say you're paying the homeless for the street cleaning service.

I certainly would. Are you arguing just because the government is interposed in the process that it is no longer a service you are paying for?

Ok, let's try a different angle. Imagine a world where financial markets aren't electronic and brokers don't exist. You have 5 Apple shares that have a fair value of $500. The only way to sell your shares in this fantasy world is to physically find someone who wants them. Maybe you call people on the phone, maybe you spam some e-mails. You get the full $500 if you find a buyer, but it takes labour and time. The labour is costing you, since you could be doing something productive that you are more skilled at. And the time is costing you, because you want the $2500 now to pay the rent, and if Apple shares plunge you could be in trouble!

So I, for the first time ever, get the idea to set up a lovely looking shop on the corner and offer to buy them from you for $499 each, and I'll handle the rest. You come in with your share certificate, we shake hands, make small-talk, exchange money. Surely you agree this is a service?

So I am slightly baffled. All that has changed is that the process outlined above has been made electronic, and now you claim it isn't a service? Do shops selling shit on ebay no longer qualify as services?
Confessions of a bootcamp graduate
Rice or UH?
"In his own studies of smoking, Stebbins has shown how the tobacco industry has turned to markets in the developing worl to make up for loss in sales first in the United States and subsequently in parts of the European market. Governments in developing nations often do not have the ability to limit tobacco marketing and, usually in need of financial help, they are open to introducing taxable commodities to their citizens. As a result of extensive advertising in developing nations, Stebbins notes that worldwide tobacco consumption has increased at the rate of 1 percent per a year, and countries such as Brazil, India, and Kenya exhibit the greatest increases (1990)."

This is from Bryan Page's "Comprehending Drug Use." It's a textbook but it's accurate, well-cited, and well-written.
cough cough fewer than... cough cough...
Tor users and Linux Journal readers are classified as extremists by NSA