skysight-inc/HackerNews huggingface dataset:
A microbiome treatment for C. diff (which is what the article mainly focuses on) seems eminently plausible, and an effective treatment can't come soon enough. However, for a lot of the other diseases that the title hints at (and are mentioned in only one paragraph in the article), there's just not that much reason to be hopeful. We have a pretty good handle on what causes cancer, and while you can tell a story about gut->immune system->{cancer, liver disease, OCD}, there's just a lot more places for things to not work.

[1] has a great summary of the current state of research on the microbiome-health connection: "We still don’t really understand what these microbes are doing, so we can’t infer what their absence or presence implies."

[1]http://www.theatlantic.com/science/archive/2016/06/the-plot-...
"On one hand, I guess it could be seen as a lack of confidence to not do your own thing. But on the other hand, it could be seen as not letting your ego get in the way of recognizing a good idea. I can see both sides and honestly, I don’t know where the truth lies."

Thats an interesting distinction he makes between the type of person it takes to be an early employee vs a founder. Both take on huge risks but as described here its a very different profile.
EBay brings AMP and eCommerce together. Launches 8M AMP based product pages
Assuming development continues as today we should have the first (synaptic level) human connectome ready around 2035. Should be interesting.
I Get Paid to Hack Pornhub
Many telcos throttle limit that route. I know of one company who used that method for sending texts from alarming to their oncalls. When they had a major incident and lots of pages went out, AT&T ended up blocking them from sending messages that way for a few hours, and they got warnings from the other major ones.
New SQL Editor for Apache Hive and Impala in Hue
> I do know quite a bit about physics. But if I just said the EmDrive is nonsense due to conservation of momentum (which is the 100% correct answer with no caveats), people would shut me down because "NASA scientists know what they're doing".

I wouldn't. However, I would ask why you think violation of conservation of momentum is completely dispositive, rather than just a strong reason for great skepticism?

From Noether's Theorem [1] we know that conservation of momentum is a consequence of physics being invariant under space translation. As far as I've been able to find, we don't know that a universe that results from a big bang must be isotropic. Observationally, ours appears to be, but there are some hints that it might not be, and scientists are taking those seriously.

[1] http://math.ucr.edu/home/baez/noether.html
That's an unfortunately ironic response to a comment that basically says "I'm getting blinded by these bicyclists headlights".
Your last point is the secret to enjoying a lot of great, "difficult" things.
Vice on HBO recently (June 24/2016) did an interesting segment on this subject.
Yes, that's exactly it. In science, rationalism (Descartes, Leibniz) has been much more fruitful than empiricism (Locke, Hobbes, Hume...) It's really strange when you think about it. The guys who trusted in divine order ended up discovering tons of things, while Francis Bacon, the father of empiricism and the modern "scientific method", didn't discover anything. That's a big part of the reason why I identify as a rationalist.
Tips for choosing a good PaaS for your biz
The Share the Safety site us back up now.
Hmm article seems to miss socialeconomics aspects. Can it put too much power or wealth in hands of few? Can hackers cheat AI to its advantage?is it more risky than current systems?

Analogy, the article analyze as if main risk of nuclear power was accidents or uncontrolled reactions. However the main problem with nuclear is with weapons which could give destructive power to few individuals. Sometimes civilian use cases can be mixed with military one (e.g. Iran, North Korea).
I'm blessed in living in a country with perfect 4G coverage and data plans that make it enjoyable. We have generally three sim car types: normal phone sim (roaming, voice and some limited data ~5-10GB but you can tether), tablet sims (around 20GB data only with roaming) and stationary internet sims (unlimited data, no roaming, no voice).

I have two of the latter and it boosted my happiness working from coffee places. I bought a good portable 4G router with 12 hours of battery and that worked out so well for me that I actually cancelled my wired home internet.
You were being condescending towards people who don't know about Baez and Tao. Bring critical of crackpot theories is warranted; the flimsier the idea the more pointed the criticism. He isn't nasty though.
Haven't touched Java in a decade and that is beautiful. I like Ruby's functional idioms and LINQ though.
I am so happy HST's mission was extended for another few years [0]! I would have funded a Kickstarter to keep it going, to be honest. If there's one thing Hubble does well, it's that it capture the hearts and minds of muggles like myself. HST is an amazing piece of machinery.

[0] http://www.nasa.gov/press-release/nasa-extends-hubble-space-...
You are aware of the fact that 'To get a bigger piece of a large market and hopefully profit in the future' means that they are actually choosing not to profit today but to reinvest their profits?

This is a common strategy in a growth market, such as mobile. And of course they have every incentive to collude because it would increase substantially those profits that they can then re-invest.

In other words, there is no downside to such collusion, and lack of profits in the present does not count as evidence given that in other markets such collusion has already been widely documented.
Congress shall make no law respecting an establishment of religion, or prohibiting the free exercise thereof; or abridging the freedom of speech,* or of the press; or the right of the people peaceably to assemble, and to petition the Government for a redress of grievances.

*Except when it involves a lie or violation of a trademark.
I'm curious what do you think is absurd about working at Instagram and moonlighting at the same time?

(Note: Many Facebook employees do exactly this.)
Why won't the people doing all that work to entertain each other earn an income for doing so, thus making it so a min income isn't necessary?
"I saw how they spent their time and didn’t find it interesting or very rewarding."
it may not be interesting but I'm sure it's quite rewarding (as in money/wealth)
Yeah, I'd like that too. For a while I was running with StartSSL removed entirely, but eventually I run into sites that used them, that I just couldn't live without.
I feel that given trials, regulatory approval, and all the other obstacles facing new drugs (briefly referenced in the article), "Coming Soon" is the height of hyperbole.
Yes, they should have responded. That was definitely not smart.
That is why many people have often called for tax simplification. The Flat Tax proposal (and for you progressives, yes we can make it progressive but that not the point) is designed to be as simple as possible and to provide few loopholes.

This is not the end all solution but it at least makes everything far, far simpler.
It doesn't claim to give all the aspects; only some concrete and fairly well-specified ones.
I've never been subject to DOS in fifteen-ish years of running SMTP.

Personal users aren't of interest to DOS ransomers since a call to the ISP will drop their traffic at the border. Without SLAs costing me money, as would be the case with a big provider, I coulf outlast the DOS. Just inconvenient and annoying.
10-year-old awarded Paris fellowship to help build her robot
Another question: What will change if UK leaves EU but stays in EEA (like Norway and Switzerland)?
From my perspective, it's like branding something with names like Stalin, Dahmer or Ames. I really wish more people would maturely reflect on Snowden's misunderstanding; pride; failure to avail himself of legal means to correct his misunderstanding; and ultimate treason. He has caused extraordinarily grave damage to his nation's security and — since that nation is the sole guarantor of global security — to the security of mankind. From my perspective, he should be despised at worst, pitied at best.
Saturday Night Live has been running parody advertising purporting to originate from real organizations for decades. I'm not a lawyer, but no one here has satisfactorily explained why this group running a fake NRA ad is a different animal from SNL running a fake McDonald's ad.

Also, assume nothing about my political views. I'm not an NRA member, but I have spent a couple of nice Saturdays shooting skeet with my son and his Boy Scout troop. My position would be exactly the same if this were a Planned Parenthood parody or if it spoofed any other politics-heavy organization.
Ask HN: Which JavaScript libraries do you use for non single page applications?
Hi there.

When you have a project that is clearly a SPA there's a plethora of articles and questions about the best tool for the job. Personally I've worked before with Backbone, Ember (really early days) and very little AngularJS.

More often than not, I prefer to not use a library. Not even because of size or page load times, just to avoid having to deal with dependencies, all the build environment around it and sometimes the learning curve.

Almost inevitably after some period on a project, I see myself wasting a lot of time on JS-related work. Maybe it's one page with an interactive form or it's a bundle of components that are complex. But at the end of the day I catch myself thinking I'd have been better off using some kind of framework. The general overhead of writing it all myself (re-inventing the wheel I guess) when complex components come into play makes me doubt my earlier decision of not using something. We know it's all about trade-offs.

Taking all that into account plus the ever-growing number of JS libraries that are available today it made me wonder if there are libraries that stand in the middle that I never heard of? Certainly HN can answer that.

If you were building a non single page application today with maybe some complex interactive pages. What libraries would you use?
Love the concept. How about web snooping? Like "verify whether or not this person worked at this job on this date"?
Every thread about UBI is full of people doing this same math. Anyone who thought that you could have UBI without taxes to zero it out for most of the population has long since been convinced. Who are you writing this for?
Apple's App Store Review Guidelines used to warn against taking complaints to the press:

"If your App is rejected, we have a Review Board that you can appeal to. If you run to the press and trash us, it never helps."

https://developer.apple.com/app-store/review/guidelines/2016...

The current version, published on June 13, 2016, omits that statement:

https://developer.apple.com/app-store/review/guidelines/
I think just the opposite is true. Amazon has more reputation as risk and will go through proper due process. Small companies probably don't even have that conversation internally.
Has Suge responded to this claim by Digital Ocean? I wonder if these e-mails just got flushed into an endless e-mail bucket.

That's the issue when you build a service hosted on a service (DO, AWS, Rackspace). You could have thousands of customers, but if you miss one complaint about one customer, the whole thing goes boom. It's more of an argument for content creators hosting on the platform controlled by the data centre owners.

For Surge, and other large hosting platforms, it's an argument for them hosting their own dedicated servers in a data centre (which of course, raises the barrier to entry and costs for these types of solutions).
Pay Google pay! As everyone else!!
> something a lot of newbie/hopeful audio engineers obsess about is "mic bleed", where the mic for one instrument picks up sounds from another. I mostly ignore this.

A better approach to "removing" bleed is instead to make sure the bleed sounds good.

Euphonic bleed is solid gold.
Fraud has never been protected speech. If it was, Bernie Madoff would be a free man. Same with defamation.

You really think that these laws have never been challenged before?
Feds and Cops Encountered Encryption in Only 13 Wiretaps in 2015
I am infuriated that people think that crime in Muslim countries represents Muslims, but crime in other countries represents criminals.
Those words have actual legal meanings, neither of which apply to the Yes Men making silly videos. I'd love to see the NRA prove actual damages.

Or as Popehat put it,

The First Amendment Protects Satire Even When Reckless, Stupid, Or Ideology-Addled People Fall For It

https://popehat.com/2013/11/26/the-first-amendment-protects-...
Invia isn't shipping a product. They're just demoing a prototype under ideal conditions. Their robot doesn't look robust enough for a real warehouse. In a few years, they might be able to compete with Kiva, but not yet. If you have a distribution center with Kiva robots, and need to replace them now, you have a problem.

A Kiva warehouse is just a big space with a flat floor. It's not like the old Automated Storage and Retrieval Systems, with their custom tracks, conveyors, and towers.[1][2]

[1] https://www.youtube.com/watch?v=It7qr6fga3c
[2] https://www.youtube.com/watch?v=LuvrP1QKsdk
This was posted earlier, with a link to the OpenAI blogpost: https://news.ycombinator.com/item?id=11950687
But... if you maximize your cognitive potential it'll make you clever enough to realize you should change jobs, n'est-ce pas?
or at 4.8T in US retail sales you could have a 80% retail sales tax.
Sorry but you are wrong here.

In the case of TMUS and S, and any other publicly traded company the imperative is to maximize shareholder value. Sprint especially is on the ropes. Investors worry a lot about a bankruptcy in the next couple of years. It has every incentive to change the status quo, and is cutting rates across the board to bring in subscribers.

It's not irrational if T-Mobile and Sprint believe they can eventually turn a profit, and probably compress the margins of T and VZ due to greater competition.

Sprint hasn't invested in its network in part due to cost-cutting. All of the carriers have to market. They are retail consumer facing.

I am not saying we should feel sorry for them, merely that the likelihood of collusion from Sprint especially is very low.
Okay fair point. Though I don't necessarily see the correlation to taxation. I assume what perhaps is being implied is that the money from taxation can be used for ethical or unethical practices (as oldmanjay points out). Yet that analogy skips how tax is only possible with profit, not to mention the fundamental issue of whether or not taxation of profit is ethical in the first place.
In my thirties now, after spending my twenties in pursuit of wealth. I can tell you unequivocally, as cliche as it is, accumulating money/wealth is not rewarding. Of course one needs a certain amount to be comfortable, but obtaining more has absolutely not made me a happier person.

Relationships, interesting purposeful work, and travel has been what I have found to be the most rewarding. Basically experiences over things.
Shouldn't?!
Android without Google: a brief and mostly uninspiring history
He's talking about how he personally found it.
And yet it manages to retain the enduring interest, both cognitive and financial, of other people who are no less likely to be of above average IQ than Hacker News commenters. Perhaps there's something about Urbit that makes it unappealing to people who are likely to hang out on Hacker News, or vice versa. Or perhaps it's doomed and those people just haven't noticed yet. Or something else might be going on. There's really no telling just yet.
Interesting, at 0.25USD/transaction it's starting to approach the same rough order of magnitude as credit card fees. It's still cheaper, but not vastly so. I recall one of the benefits of Bitcoin was supposed to be that transaction fees would be greatly reduced. Are they independently discovering that fees actually need to be higher, or is this just an anomaly?
I was thinking the same thing. Some statistics about early employees vs founders might be interesting too.
Show HN: 2D Portals
> > This is a dumb question. We are not going to eliminate Social Security and Medicare etc.

> -- Richard Thaler

Yes, you're not alone in that thought.
It's a terrible idea if you have any regard for democracy. Indeed Merkel tried persuade the UK Gov to revert the vote like the Greek PM did a year back, but after Cameron's visit to Brussels it was clear that such a thing can not happen in the UK. Greece acted as a protectorate while the UK acted as a democracy. Mind you, in order to turn the UK like Greece, you need to bomb it. Not just London, all of it... That's how bad Greece is today.

If a PM do what you suggest and he doesn't bring something staggering like 10% growth, your next PM will Farage. I assure you that most of that 52% will vote someone who'll get the job done right away.

Instead of taking for granted that only an idiot would vote for Brexit, it's a good idea to understand the reasons they did. It's appalling but even my beloved John Oliver seems to have a very low regard for democracy when the populace doesn't deliver what he thinks it's right.

Given the latest developments within the EU, I would not worry too much. The EU will tore itself apart before you end up the negotiations with Brussels and at that point we'll be probably at square1 and you'll have the upper hand as your economy is bigger then most in Europe.

Off topic but still: I believe May will be the new leader. Gove eliminated himself and Boris Johnson in one blow :-)
When was that amendment passed?
> Having it all work intra-nationally would be really cool!

You mean _internationally_, right, or did I miss something?
I'm not trying to pretend that was a victimless crime - it was bad and it negatively affected people, some to a deadly extent. But the degree of risk here for all involved is night and day compared between the two.
Nothing, but they'll not allow you get a deal like Norway's or Switzerland's because if Brussels do, other will follow suit.

Doesn't that say a lot about how much everyone loves Brussels? :-P
Child exploitation content is an unfortunate canary in the coal mine for free speech. If a service or network is robust enough (in terms of censorship resistance and anonymity) for them, then it will be good enough for you too. On the other hand, if whatever platform you are publishing to is free of this objectionable content, then yours isn't safe either.
Exactly. The differences between minimum wage and UBI is fascinating, but I didn't want to bring it up above.

To me, minimum wage says "if you work, then you should at least able to support yourself on your income$." UBI+ says "if you work, you must find greater fulfillment than mere sustenance in your work."

Personally, I can't see minimum wage applying to anyone receiving UBI. Although it might make sense to have a "less than minimum wage" tax that helps fund the UBI directly.

$ Abstracting away actual amounts and whether or not they're enough

+ Market adjustments aside
It's about the scale of your app. If you are small fish, going to the press isn't going to accomplish anything. Spotify can afford to press the matter. What worse can Apple do to them? Remove their app from the store? Spotify can afford to litigate against that kind of anti-competition.
Show HN: Using machine assistance to diagnose incidents faster
What's to stop a troll from setting up a signal at arbitrary locations and ruining people's pictures?
How does this work in brick & mortar businesses? Is there precedent for forcing a retailer to stock a particular product?
Hi, I'm the founder of Overseer Labs. Companies that are data driven and care a lot about reliability seem to suffer from the "too much data" problem during an incident. Thus, we wanted to develop a tool that would help them sift through their data and help them root cause the problem faster.

Overseer Labs leverages machine learning to model system behavior during normal periods of operations. Afterwards, the trained model is applied in real-time to find strange behavior and then providing a ranking of all your metrics. By correlating these insights with your PagerDuty alert, you will be able to resolve your production problem faster.

We put up a demo of one of our algorithms so you guys can play with it on a small dataset. No algorithm will work perfectly out of the box for all the datasets out there, but if this looks useful for your company, we can tune it for you.

I'd love to get feedback from all the data driven companies here on whether or not something like this could help.
I would like to echo what Brandon has said and can highly recommend Craft not just because it's an awesome, flexible CMS (and it is) but because it is stable and extraordinarily well supported.

Out of the box it performs well when compared with other CMSs (I can't find the stats right now) and for the majority of sites can be used without needing any third-party plugins. However, if you do need to do something more custom than a CMS will generally allow you Craft gives you a clean plugin architecture to work within. Plugins essentially take the form of small apps that look much like a Laravel app.

Whilst all that is great there are two things that really make it my choice for day-to-day development: the community and the support from Pixel & Tonic. Regardless of if you have one site or 100, stellar support comes as standard. I've been building Craft sites since the early beta and have never once not had a question/bug/feature request dealt with in a timely manner. In most cases you get a response within hours, and often a fix or feature within days.

Add to this the thriving community of developers who can mostly be found on the Slack group and Stack Exchange site and its win win. Just join the Slack group and watch the #help channel for about 10 minutes and you'll see what I mean.

I honestly think after years of experience that you won't go wrong with Craft. Your content will be yours to own and move around, you won't be locked into a way of thinking that doesn't fit your structural needs. Your design and templates will be an actual joy to implement. Frontend devs will rejoice, editors and admins will hug you, backend devs will get EXCITED (I do) - the entire team however small will literally take a deep breathe and thank their choice of deity.

You get my point. I'm happy to go into more details about the guts of Craft if you like, just ask away, but for now I think I've gone on enough.

Go forth and Craft something worthwhile.
Show HN: Mapping jobs 30 minutes from home without a car
I pay $5 / month for google apps for my personal domain. I've had to contact support twice, the first time I got a phone call < 10 minutes after my email, and the second was < 20 minutes via email.

In my experience, Google support is _excellent_ for their paid products.
Instant React Native List Views
> You call DominikR's statements "misinformation", which amounts to a claim that they are false. You're every bit as much on the hook to substantiate your claims as he is to substantiate his

I strongly disagree. He makes the claims; it's up to him to substantiate them. It doesn't work if people say anything they want and ask others to falsify them; we could all make up statements all day.