skysight-inc/HackerNews huggingface dataset:
So the primary motivation seems to be spurring DNA synthesis technology. Why go straight for human? I'd rather a synthetic c elegant genome or possibly mouse.
There are clinics and doctors that have been performing the procedure, lowest cost I have seen is $7k for a treatment. They can harvest, isolate and deliver his own MSC via IV and perhaps nebulizer.

It seems like the doctors that have been performing are silos of information right now. There is not a lot published on the web of their experience as practicing doctors, some of the best on the ground info I have found is from interviews of doctors practicing.

There are also very many published MSC trials showing a benefit.

It is a terrible thing to not be able to breathe well. I hope that this can help.
Nope, I'm afraid I was using the Visual Age class library (which was pretty good) for most if not all of the development work I had a hand in.
The Microsoft part of the OS/2 2.0 fiasco is so bad and unethical it is one of my favorite topics (I'd say it is even worse than Longhorn).
From the NYT article in 2011:

“The choice is radical, but brilliant,” said Larry Smarr, director of the California Institute for Telecommunications and Information Technology, a University of California laboratory that pursues a similar research agenda to the Media Laboratory. “He can position the lab at the edge of change and propel it for a decade.”

Mr. Ito’s appointment comes at a time when the Media Lab, as well as other information technology research centers, have struggled to reclaim the financing levels that were characteristic of the era of the dot-com boom. Although the lab gets the bulk of its $35 million annual budget from corporate and government sponsors, that amount has declined measurably as a percentage of the overall budget during the last decade, Dr. Negroponte said.

“Funding got tight in 2002 and even tighter in the last economic downturn,” he said. That has made fund-raising the highest priority for the new director, he said. However, he added that Mr. Ito’s particular leadership qualities made him stand out among the 250 candidates who were considered for the position.

“Joi is very good at enabling others,” he said. “I’ve never met a 44-year-old who is able to enable others in this way. Most people who are at that age are into themselves and their career.”

L. Rafael Reif, the provost of M.I.T., called Mr. Ito “the right person to lead the Media Lab today,” describing him as “an innovative thinker who understands the tremendous potential of technology and, in particular, the Internet, to influence education, business, and society in general.”

Mr. Ito’s colleagues minimize the fact that he is without academic credentials. “He has credibility in an academic context,” said Lawrence Lessig, a professor at Harvard Law School who co-founded Creative Commons. Mr. Ito is currently chairman. “We’ve been collaborators, and I’ve stolen many ideas from him and turned them into my own.”

The Media Lab will benefit from a director who has Mr. Ito’s global connections, said John Seely Brown, former director of Xerox’s Palo Alto Research Center. “What they really need right now is to have a two-way connection to the outside world. Who more to do that than Joi?”

http://www.nytimes.com/2011/04/26/science/26lab.html
Dynamic linking offers modularity and separation of concerns.

I don't really care which point-release of zlib my program is linked with, I just want to decompress stuff. If someone finds a bug (or exploit), I am not the best person to quickly realize it and release an update -- the maintainer of zlib, and the packagers, and OS distributions, and sysadmins are in a much better position. But if it's statically linked, then developers have to be involved.

You could say that we could invent a mechanism to allow sysadmins to rebuild with patched libraries, but then we'd still need to reinvent all of the versioning and other headaches of dynamic libraries.

I think dynamic libraries are kind of like microservices. Sure, they can break stuff, but they allow higher degrees of complexity to still be manageable.
> It represents a real failure of leadership on the part of the President if parts of the executive are ignoring OLC opinions.

Whatever it might be executive-branch-wide if non-DOJ agencies were doing that, its a failure of leadership within DOJ if entities within DOJ are ignoring OLC opinions. Which is the issue here; the lowest common level of authority between FBI and OLC isn't the President of the United States.
Oops, I guess you're right about that. I took the expression "nary a penny more" to mean "nary a penny more [than 1000 talers]", since I assumed that Vieweg still bought the manuscript. I see now that this isn't explicit at all.

But Moldovanu & Tietzel (1998) [0] do report in their article that "Vieweg offered exactly that sum [1000 thalers]". So there it is!

[0]: https://www.econ2.uni-bonn.de/pdf/papers/goethes_second.pdf
Sorry if I offended anyone by using the term "embedded systems" in this context. I think of an embedded system as a large umbrella group for application-specific hardware/firmware configurations; maybe that definition doesn't hold water. It certainly differs from the popular "real-time performance" definition, which I believe is just a large sub-group of embedded systems.

I've altered the title of the post to use Nerves' actual tagline.

Disclaimer: I work for a company whose products are based around SoCs running Linux for soft-real-time applications, and we whole-heartedly call these products embedded systems.
For 90% of my photos, yes.
I did NOT call her "hot"; I said "she is not looking so hot now", which is a common idiom, and is unrelated to calling a woman "hot". If you don't understand common English idioms, then maybe YOU should stop posting here until you can learn some common English.

I just took the previous comment, and pointed out that she no longer looks that way, and that I think current events have a lot to do with this apparent change in her appearance. I do not see how this is either uncivil or lacking substance.
>> more memory

http://programmers.stackexchange.com/a/189552/4334
Breaking up a comment into isolated parts removes context and is intellectually dishonest, please don't do it.

What you're doing now is invoking moral outrage, which is completely useless in any real conversation, so what you're signaling is that you've completed being useful to talk to, and are now commencing your own justifications for continuing to believe as you do, despite a well-reasoned argument to the contrary.

You've unleveled the playing field by removing rationality from this conversation, but by continuing to use terms from the world of rationality (evidence, claims), you try to mask that fact.

Do you realize that when you do this, you isolate yourself and alienate the person you're talking to? I don't want to talk to you anymore, regardless of the validity of your other points, simply because of how... annoyingly self righteous you're being. It's like a religious conversation now, and why would I engage someone on the Internet in something like that?
Yes, the Windows tax is not cheap, nor are they nearly as easy to clone and manage in a virtual environment. Linux is simply a superior server in virtually every conceivable way but most especially financially.
> Somehow I would like they would have focused on value types and reified generics for Java 9 instead of jigsaw and postponing them to Java 10+.

I hear you. Cost-benefit wise Jigsaw doesn't look attractive to me. To be honest I would have preferred Java 9 in the fall of 2016 without Jigsaw.
I'm curious if the Microsoft of today has learned its lesson and changed its ways? As an outsider now, I see lots of positive things going on such as acceptance of other platforms (especially Linux), open source activity, etc. Is Microsoft a good place to work again for a hacker (who doesn't play politics)?
Universe is expanding up to 9% faster than we thought, say scientists
Agree, XML is fantastic and a much better choice than JSON for everything except being parsed by JavaScript. JSON has one use in this world, JavaScript.
The "seedier" actors in the ad space have always been about arbitrage. You can argue all you want how they're destroying the web, but the fact is they can purchase cheap traffic and remonetize it for gain. That's the definition of arbitrage and it exists in all types of industries, and is usually not viewed negatively.

Advertisers are in full control of assigning value to a traffic source by way of demographic targeting and bidding... Either the Advertisers are still profiting over the whole interaction or they're bidding too much for their traffic. It's not the middle men who are to blame.
If your PR is merged, then I will try this out.
All of these "channels" are just different ways of making sounds. Call them whatever you want they still use the same medium.
> Examples: climate change denial, anti-vax, religion...

It's just a tad naive to list the entirety of religion with climate-change and anti-vax and then conclude that the sole reason that religion exists is "fear of things people don't understand". Do you know anything about religion at all or are you just parroting what you read in the news about American Christianity?

It's funny to me because this kind of thinking seems to indicate that you are "Someone who sees things in black and white, ignoring the complexities of life, [who] will respond with simple, ignorant answers."

Furthermore, the vast majority of people who are pro-vax and anti-religion have made up their mind based on nothing more than social cues. They're not scientists and they have to trust what they're told just like most people.
Ok?

I am not denying that, but I'm not seeing how it's connected to me telling the "OMG helping women is sexism" guy that there's a history here that he should pay attention to.

In particular, the historical comparator to nurses isn't software engineers, it's doctors. Take a look at the gender distribution of medical school graduates:

http://4.bp.blogspot.com/_otfwl2zc6Qc/SwyK7qFvLaI/AAAAAAAAL_...

You can see it take off with Title IX, which banned outright institutional discrimination by gender.

A lot of women with interest in and talent for medicine who wanted to become doctors instead became nurses, which fed that historical imbalance. We've fixed the schooling, but we're still working on the outcome; the gender distribution of doctors is still not great: 66% male in the US.

So when this guy whines that there are no organizations helping men become nurses, my reply is that the reason women have historically dominated that field is not anti-male barriers to dudes who really want to be nurses, but previous anti-female barriers in the higher-status profession of doctors (and other things they could have done).
Not saying this destruction is happening or not, but their data to support their claims is dreadful. All circumstantial viewing of links and pages, google news trends, and Alexa profiles. Sadly, these days claims that may be correct can be ignored when the supporting data supplied is weak (and vice versa).
> The reason for this is that 1/3 cannot be precisely represented in decimal but (maybe somewhat surprisingly) it can be in binary, hence the correct result for 1/3 + 1/3 + 1/3 = 1.

1/3 cannot be precisely represented in (finite) binary. Its representation is 0.0̅1̅.
Contrary to what many people think, few of us have managers who can consistently and successfully lay out the optimal career path and help us achieve it. I'd say there are three main reasons:

1. It's really hard to do.

2. Few people have themselves been trained on management.

3. Faced with 1 and 2, people focus on their own, more familiar personal deliverables.

Therefore, if you want things to change, you'll probably have to make some specific suggestions. And to do that, you should do some homework. I highly recommend starting with Managing Humans by Michael Lopp (http://www.amazon.com/Managing-Humans-Humorous-Software-Engi...) or maybe The Hard Thing About Hard Things by Ben Horowitz (http://www.amazon.com/Hard-Thing-About-Things-Building/dp/00...). Spend an hour or two with each book and you'll have a better idea what can be done, and why.

What you're finding is that working as both a full-time manager and full-time engineer is very difficult, borderline impossible. Eventually, you'll have to choose. An increasing number of small companies are starting to understand this reality, and allow their top people to grow into either technical leadership or management leadership roles. Expecting both, simultaneously, is not realistic.
Snapchat secretely acquires Seene
I have, very occasionally, been extremely grateful to have seen ads. I don't want ads to go away, I want irrelevant ads to go away. I really wish that:

1) When I bought something on Amazon, they would advertise products other than the exact one I just purchased.

2) There was a chrome app which would, every week, ask me what personal projects I was working on and then replace the existing ads I saw with ads that would be relevant to the problems I'm willing to spend money on.
> > Comments about how "hot" a woman looks are below HN's standard both for civility and for substance.

> I am not the one who called her "hot". Don't blame me for that. I just took that comment, and pointed out that she no longer looks that way

That is still a comment about how "hot" she looks, and dang's description of the problem with your post is not addressed by your attempt to defend it. The original poster who raised the issue was flagged, so you can't even assert that there is an issue of hypocrisy where the downvotes on your comment about how "hot" she looks were out of line with the treatment of the person who started that out-of-bounds discussion.
I don't think I'd agree that Nerves is "firmware". Nerves is, at its root, buildroot linux and Erlang, with an Erlang "init". At least the last time I looked, the "hardware interface" was just file I/O operations in sysfs. Which is cool and all, but that's just a process in Linux userland reading and writing files.

I spent quite some time trying to get tighter integration between a kernel module and the Erlang runtime. Because of the way Erlang works, one can't select(2)/poll(2) file descriptors in a useful way, which makes sysfs interrupt files less useful. I wrote a very simple Erlang node[0] to send messages when select/poll returns. It works okay, but the jitter is very high.

Peer Strizinger wrote something called Grisp[1] which uses the POSIX interface to RTEMS[2] to run Erlang without a canonical OS. RTEMS is still ultimately an embedded kernel, but it keeps you much closer to the metal than Linux. Unfortunately, Peer hasn't/won't release his code despite my pleas.

Most promisingly, there's Cloudozer's Erlang on Xen port to the Raspberry Pi[3]. This is a clean-sheet Erlang VM implementation that actually runs bare-metal (no POSIX!). The code is definitely experimental and I don't have the time to try to retarget it to my preferred platforms, but it's exciting anyway. It's definitely what I would call "firmware" in Erlang.

Anyway, Nerves is cool, but it's (u-boot + Linux + epmd + BEAM).

[0] https://github.com/thenewwazoo/erl_poc/blob/master/c_src/nod...

[1] http://www.grisp.org

[2] http://www.rtems.org

[3] https://github.com/cloudozer/ling/tree/raspberry-pi
A large chunk of what I do has nothing to do with writing code or solving problems... Sales, accounting, contract negotiation. They are more time consuming than they need to be, but at least cost of doing them is very much built into my rate.

They are tedious beyond belief. Work for trade has gotten me the help I need in these areas from accountants and lawyers and built some solid relationships that I didn't have before. This is all upside for me.

I can't stress to you enough how important the contract is, if you were thinking about a consulting style business you need to watch this before you dive in: https://www.youtube.com/watch?v=jVkLVRt6c1U
Does this bring anything to covnersation? What does gmail or docs have in common with forcing youtube users to use google+? Please, read and understand what was written rather than turning to bold statements disconnected from the topic. I was very clear to mention youtube came out first, so neither of your statements apply.
Call me crazy, but I think long term this will be a good thing for Java. (I am one of those people who actually enjoys Java, I know call me crazy)

My organization for example used to be all PHP and JavaScript. This whole "static language" thing is new to them. They tried C# and thought it was the greatest thing since sliced bread, (along with Go). So they heard about Microsoft going "open source" and decided to give it a spin. Now with the 'boiling the ocean' article ringing true for many, people are starting to get some heartburn about having to get in bed with Microsoft.

I stand over in the corner and raise my hand occasionally and say, "How about Java?" every now and then.
I find it interesting how the media accepted their large bounce rates, and decided to monetize them with Taboola and Outbrain.
the tiger-buffalo analogy blew my mind - it's so awful
Build a video platform
Anyone interested in contributing in this new video streaming app?
https://github.com/stoufa88/lawd-desktop
Designing Interactive Experiences Using IoT
TL/DR: An interesting, adjective-heavy story about how Facebook and Zuckerburg responded to the Google+ competitive threat between 2012-2014. Zuck likened it to Roman conquering and Facebook went temporarily into "Lockdown" with seven day workweeks. Anecdotes suggest Facebook worked Sundays more often than Google. Otherwise pretty light on content.
Yeah, those invites have been going out for a while now, I've been receiving them for the past 2~3 months. I set up a fresh windows 7 VM with the intention of seeing what would come of the requests - but none of them ever came online after accepting.
Hi everyone! That's me you hear talking to Patrick ;) If you have any questions about the episode or salary negotiation in general, ask away! As you can probably tell, I love talking about this stuff!
Why You Should Be a Famous Founder
Lifelock should just be regulated out of existence. If a company can add $100 of value per year by pretending to monitor credit reports, the credit bureaus can be instructed that whatever Lifelock is doing is table stakes for a company that is selling evaluations of creditworthiness.
I won't disagree that that feeling is reasonable or justified. I've worked at a number of places where someone who felt that way would have been supported if they chose not to participate.

That being said, Academia is the only place where I have worked that it was considered okay to demand that others not be allowed to participate. Especially, demanding that students who may or may not feel the same way be barred from attending.
> tech "journalists"

ah the old cut and paste from one site's article, rearrange some words, grind it through a thesarus-izer, then repost.
>> overhead of starting up the JVM both in time

Not much for those programs:

http://benchmarksgame.alioth.debian.org/sometimes-people-jus...

>> It's pretty easy to see … memory

Yes: http://programmers.stackexchange.com/a/189552/4334
How Trump hijacked the authenticity of the web
I still twitch a bit over the WebSphere branding apocalypse when they decided their (IMO ghastly) Java app server's name should be applied to All The Things.
All the sources he talks about in the article, except debug information, don't grow with program size.
If Google does it, they can as well sneak in some of these to Play Music play lists, see the response on no of replays and stuff and gauge the overall quality and likability. Basically crowd source the reviews.
I find most adds can be skipped, but if you enable adblock they are unskippable.
This "research firm" has been super bearish with regards to Google/Alphabet and is obviously short. All of this "adocalypse" talk seems somewhat overblown. Besides, even if Google's display ad business went to zero, it would certainly not exactly kill 3/4 of their revenue and/or profits (because there's still all the search ad business).
That is probably made on porpuse because of their view on user experience is based on "clicking videos". So they want you to click from video to video rather than search your stuff directly.
Exactly, turn HOMM3 a MMORPG. A little bit like bombermine (I don't mean rules, only the idea to make it available to multiple players at the same time).
Can someone explain how the toasted balls play works? Are they arbitraging by buying cheap porn ads then selling higher priced ads to the same traffic?

I don't see how this would work, except for the paragraph that follows in the article talking about "laundering" traffic to make it appear higher quality, so maybe they get good money for their ads? But still, CPC is generally not cheap compared to CPM.
.. and you're wondering why they're not like you, who'd be willing to work an 80-hour week for 2-3x the salary versus their 40-hour week and 1x salary?

You mention commissions; I'm not clear whether you're talking about salespeople, developers or consultants? Or something else? Only the former traditionally work on commission.

The thing is that each additional hour of work has a nonlinear "cost" to humans. The 80-hour week is something that not everyone can do in the same way that the 3 hour marathon is not something that everyone can do.

I suppose I really need to do a nice writeup of my experience where, due to chronic fatigue, I had no real alternative but to work 25-hour weeks for a few years.
Just came to say thanks, WikiTube is awesome.
The original blog post is one of the best reads on the topic. Especially for people who never tried to negotiate before or always failed.

http://www.kalzumeus.com/2012/01/23/salary-negotiation/
In that specific example, yes, but compliments are often given because of the design, and in those cases it makes sense to give credit to the designer.
Direct link to bill referenced in title:

https://www.eff.org/files/2016/05/25/114th_may_2016_whitehou...
No, not that deep. I simply mis-read the parent and though it said "more"...
One of the differences is that the same types of garbage ads that fill gossip magazines (and the back pages of good magazines like the New Yorker) is that these ads are being pushed to us front and center of nearly any site you visit.

I avoid these ads in print. It is easy to not read magazine or skip the back ads. I don't even feel that I give the front ads of the New Yorker or the Economist much of my attention. I can easily passively avoid ads in print.

Online, ads have become highly annoying and detract from the experience of website in a way that does not happen in print.

I am not saying that I entirely avoid print ads. Back in the day of Creative Computing and Byte Magazine, I would pour over the ads as much as the editorial content. The ads were interesting to me.
I don't think it was offensive at all. The smartphone/SoC era has just blurred the lines. We can now have dedicated application processors that do incredible things, stuff that was inconceivable a decade ago.
"tools" don't always exist or may not be available. So, as with all software, it must be possible to edit the files as text with a good developer experience.
Drill an artesian well and hope that nobody notices the spelling?
What’s your morning routine?
and those people keep things free for the rest of us, so I'm fine with it. Everybody likes to complain about advertising but no one has come up with a way to eliminate it without a large portion of the sites we use everyday shutting down.