skysight-inc/HackerNews huggingface dataset:
Completely agree. I often got frustrated that the "modern" featureful IDEs don't allow me to incremental/regexp search in drop-down menu items nor to use set-mark-command + kill-ring-save keystrokes within dialog messages.
Twitter must be such a popular target for the Intelligence crowd that I wonder how the heck they coordinate all those NSLs and whatnot. Is there a clearing house in the USG that handles that?

"Look, that's like the fifteenth request for the 'Whole Banana' this week. We're gonna have to --"

(telephone murmurs)

"Fine, so you have a nosebleed level pay grade. Sir. But there's more Twitter bandwidth going to you folks in DC than there is to all of the /real/ users of Twitter. It's embarrassing. Why can't you just go down the street and ask the CIA?"

(angry murmurs)

"Or the FBI. I hear they have a special on faking evidence with parallel reconstruction this week. Want the promo code?"
> Confidence is simply how much confidence you have that the predicted class is correct.

If you mean correct among the number of output nodes, then we are talking about the same thing. If you mean correct among all the possibilities to include those unknown to the NN, then I'd appreciate a link - because I've never seen that before and it sounds incredibly useful.

> ...I don't know of any simple test that will give you a 0 if you're over-fitting and 1 if you're not.

Neither do I, that is why I used all those weasel words - but I also don't know of a neural network that wasn't either being misused or being overfit that returned such results. A simple example would be the 2 inputs for the xor test data, a hidden layer with enough nodes to memorize every permutation, and 2 output nodes - each representing the confidence for the potential result of the binary operation.
Uber and Lyft to leave Austin. Why do they oppose fingerprinting?
3m?
Paris has a road tunnel with a 2m clearance. Some of us here would have our heads grazing the top if we had to walk through it.
...Unless the said person's inheritance includes land confiscated from Indigenous Australians...
I actually wouldn't expect that Indian prisons provide any effective medication against hepatitis C. You might get it if you buy it yourself, and bribe the prison staff to allow you to have it.

Sorry: this is not based on any real experience or references, just the overall assessment of how India stands currently.
I would love to live in that alternative reality. The area is crippled by small town fragmentation.
You have no facts. Merely an ideology you are wedded to and will insist on pushing regardless of the facts even when directly confronted with them, and having simple mathematical statements you make proven wrong. If the facts damn the state, people like you damn the facts, and therefore there is no reason to discuss anything with you.

This is not a rage quit anymore than realising that confronting a Christian with the fact that various points of their faith are simply scientifically impossible and thus factually incorrect. We are playing different games and care about different things. You don't care about truth and I don't care about your political agenda.

We start from completely different premises and have zero regard for the premises of our opposite, therefore discussion is useless.
Should kids in Kentucky be educated differently from kids in Yorkshire?
Lots of scientist prowess except the CEO. Not ideal.
Whatever happened to this which as supposed to also detect all cancers for $0.01 per test at > 99% accuracy?

https://www.ted.com/talks/jack_andraka_a_promising_test_for_...
Let's walk through this. Drug develop is mostly funded with private money. Yes, the NIH funds basic research that often support drug research, but private companies fund most of the bill. It's in the hundreds of billions each year.

Now why would they do that? Well, they expect that they'll give a company $500M and it will turn into $2B or $3B. However, most of those companies will fail and the $500M will turn into $0.

So that would mean that the returns on the drugs that are successful need to be really high. What if they weren't? Well, all that private money would dry up pretty dam quickly.

Look at the money going into cancer research. It's a huge amount every year. It's not just because cancer is a terrible disease and affects everyone, it's because the returns on cancer therapy are high.

You could just tell private companies, "stuff it, you don't get to make money" and try and have the gov't do it on their own. Of course you'd need to increase the NIH budget by what? 10x?

Our current system isn't perfect, but it does a dam good job aligning the incentives of people with money and people who need new drugs.
I haven't checked recently, but I hope and assume that most of the issues are going to be fixed.
I doubt it'll happen in the US because we don't really have workers dormitories for people to jump from and in the US very few people jump for suicides (~2%) vs guns (~56%), suffocation/hanging (~25%) or poisoning (~11%).

source: http://lostallhope.com/suicide-statistics/us-methods-suicide
I don't need to agree or to disagree, but I need to ask: why downvote the parent without offering any replies?

(Upvoted, just out of the feeling of irritation at this.)
Update: didn't work
Wait. Of course your insurance is cheap, it excludes in-patient care. You know, the most expensive part of medicine.

If it were legal in the US, no in-patient care insurance would be pretty cheap as well. I'll agree not as cheap as ex-US, but a hell of a cheaper than Obamacare plans.
Correction: Chances are someone already complained about something or whatever.
It should be priced according to ability to pay based on income. The same is the reasoning why the drug is so cheap in other countries, their people can't possibly afford the prices. So it makes no sense for citizens of wealthy countries to have to pay huge markups if they don't have the money. It makes no sense from an economic perspective to force people to go into bankruptcy just because they got sick.
Price controls work so well in general, why not try them in pharmaceuticals?
If you go back far enough in history someone somewhere in a person's life will have done something awful. Could have been 100, 200, 1000, 10000 years ago.
notice the release dates for the recent issues...

issue 66: 2009-11-06
issue 67: 2010-11-17
issue 68: 2012-04-14
issue 69: 2016-05-06

the intervals: 1 yr -> 2 yr -> 4 yr

Are they now on an exponential backoff tendency? Will their next issue come out in 2024?
There's a strong fair use defense for interoperability (Sony v Connectix). In the hypothetical situation that someone claimed copyright on TCP/IP, presumably that would be a strong enough defense.

Google is in difficulty here because they didn't use Java for purposes of interoperability; their version isn't even compatible. If they had, Oracle would have no case.

The appeals court left open the question of whether Java being easier for developers because they already know Java counts as a fair use defense.

It might count, and then Google is free.

If Oracle wins then in a way this might actually be good for open source; software developers would seek out the path of least resistance: APIs that could be licensed freely.

That is why the FSF supported Oracle before the supreme court.
Take a look here:

http://programmingfonts.org/

Lately I'm in love with Office Code Pro (Dotted Zero version):

https://github.com/nathco/Office-Code-Pro
I don't think anyone is arguing only Big Pharma creates new cures. In fact, most big pharma companies acquire smaller companies for their drugs.

That said, I don't disagree that money is the only motivator. However, good intentions aren't enough to develop a new drug. It takes a hell of a lot of money as well.

If you don't create incentives for private investment, then you need to get that money somewhere else.
The billion dollar part was not the math mistake, the mistake was dividing it by 26 or 27.
in an almost the same vein, i would heartily recommend 'the medical detectives' for bizarre accounts of medical mysteries and once 'debugged' almost 'obviously that's how it would have happened' explanations of those incidents...very cool :)
I agree that the configuration story needs work and documentation.

What you could try is to set the vblank_mode=3 environment variable to force V-Sync. If that helps, it means there's either a stale bad config file or a bug somewhere in the client API implementation...

Make sure you have no ~/.drirc, and you really shouldn't need an xorg.conf either.
It's not trying to make a cohesive point; it's a collection of short, unrelated posts bundled together. Many of Matt Levine's posts [0] are in this style, including his most recent post [1].

[0] http://www.bloomberg.com/view/contributors/ARbTQlRLRjE/matth...
[1] http://www.bloomberg.com/view/articles/2016-05-06/hedge-fund...
Scientists are not profit motivated. Scientists don't work to produce more drugs faster just because the CEO is managing better. This is definitely something that can be funded by the public and should be funded completely by the public on a not-for-profit basis. Then we can no longer make these sort of ridiculous economic arguments.
It was a grave blunder for Google not to buy Sun. Besides Java, they would have gotten MySQL, ZFS and some hardware that would all be useful at Google.
> And if it's morally reprehensible to not save a life when you have the power to do so, aren't all of Apple's customers morally reprehensible for buying iPhones? That money could literally save the life of someone in the world that lacks basic necessities.

No, the decision to make billions extra in profits on top of the billions they would already be making at the cost of millions of lives is still definitely more reprehensible than someone spending a few hundred dollars more than they otherwise would on an essential device that provides information, communication and entertainment instead of giving it to someone less fortunate.
What about drugs that cost more than $10 per day to produce? Hell that's only $3650 per year. How many manufacturing plans can sustain themselves on that sort of revenue, particularly if they are creating a drug for a disease that only affects 1000 patients in the world?

One of the reasons why generic drugs prices jumped so much in the last few years, if because manufacturers said "screw this" and just stopped making the drugs because the margins were so low.
Is Your City's Street Grid Really a Grid?
> Doctors next in line after truck drivers...

with imb's watson, diagnostics as well i would presume, in the near future...
There are many other ways to get hepatitis C. For instance, it is not an unknown phenomenon that drug addicts use needles as a weapon. Errors in healthcare, e.g. needles or blood transfusions.
Please list all of the drugs that public money has brought all the way to market. It's not that long.
After a couple of similar close encounters I just decided it is not worth it. The gas I have must be enough for the trip with a margin. Even if I am late, or if it is inconvenient or any other reason, does not matter, I follow this rule like a robot.
Agreed, that's exactly what I'm trying to suggest :) Eminent domain requires paying the property owner.
Do they hand out sainthoods with PhDs now? A scientist working in the commercial sector has the same motivations as anyone else.
Reading between the lines of this, and also this, recently submitted article:
https://news.ycombinator.com/item?id=11657634

It feel like the NY Times just went full court press Hillary.
I think the government should put a value on every life (or quality adjusted life year, whatever), and offer to pay that much for any drug that saves lives.

From that perspective, $84k per life saved doesn't sound that unreasonable, and creates a huge incentive to develop similar drugs in the future.

But I don't think valuing every life at $84k would be sustainable. And why should the drug company itself get to determine the price, with no upper bound?
Also, the output is a probability, but it's a single number. you don't get anything like a 95% CI, error bars, or a posterior distribution .
Is this meant to be funny?
You can't have perfect competition in the drug industry, but you can get close. Gilead dropped the price of Sovaldi/Harvoni by almost 30% when Abbvie launched their HCV therapy.

In fact, one of the best way to introduce competition is through "me-too" drugs. You know, the ones everyone complains about.
I think in the author's ideal world, the lowered profit for Gilead would mean they aren't rushing to provide Sovaldi a multi-billion dollar profit either. So the price drops well below $11 billion, and you get a solid profit margin without gouging people that need the drug.
There's a fair use defense for interoperability.

So despite all the hype, this case is unlikely to have a huge effect on the software industry.
Scientists may or may not be profit motivated. But you can sure afford a lot more scientists to work on a problem, and give them much nicer labs, and pay for expensive animal and human trials, insurance, etc.
Ratner's Star is one of my all time favorites and I still use the quote ”No definition of ’science’ is complete without a reference to ’terror’.” as my email signature.
Because why try harder when it's so easy to make ridiculous profit? Especially because the people are "criminals" that nobody wants to help?

Anyone who does want to help is outnumbered by the fierce and protective cabal that currently runs the prisons and attached services. They're not going to be displaced without some major show of force either through community action or legal regulation.
Use of Formal Methods at Amazon Web Services (2014) [pdf]
The drug from the original company is expensive everywhere, what India has is generics, which in their turn might lower the price of the original drug because of the competition. It also lowers the incentive of selling the original drug there at all (and consequently allowing the government to press for agreements). I have some unpopular opinions regarding the subject...
It is expensive, but still cheaper than treating someone in the US with HepC for life, which Medicaid is already paying.
By that logic Ford should copyright a cars brake and gas pedal and force other manufacturers to design completely new interface systems to stop and accelerate cars that aren't brake or gas pedals. Sounds great /s.

I don't even know where Cloning WordPress came into your thought process. WordPress runs on top of Apache/nginx. That is what responds to ws.com/a. Interoperability is incredibly important, unless you want to go back to having to run a specific Web browser for every other website that isn't using Web standards / rfcs.
I take Amitriptyline at night (in addition to opioid patches and antiinflammatories). While I find it does have some analgesic properties; the real benefit is actually a side effect, the drowsiness means I actually get some sleep.
You can do it mate! Best of luck!

Try switching advisors or maybe even fields within your CS department. You might start something you like
For a public site is important...
An Interview with Donald Knuth – Dr Dobb's [1996]
This entire blog is great reading material for technical papers: https://blog.acolyer.org/
Yes but not a good decision for everyone else. Someone has to pay for the development of these drugs.
Don't have insurance that would cover it

Gilead was doing that.[1] Hell, most drug companies give free drug for patients who are either uninsured or under-insured (their insurer won't pay for it).

[1]http://www.gilead.com/responsibility/us-patient-access
I agree, violently. Protecting the researching company's incentives is hugely important. Otherwise we're getting the current crop of drugs at the expense of future drugs.

Eminent domain requires "just compensation" that courts interpret as fair market value. Since the company that created the drug was recently acquired there's a really easy number to put on it.
Scientists are not profit motivated.

You haven't met the scientists I've met then.

When you're working at a start-up and have options for a few hundred basis point of equity, you can be dam sure they are profit motivated.
No. There's a fair use defense for interoperability. Wine is clearly built for interoperability purposes, so they are ok.

Google's primary difficulty in this case is convincing the jury that they have a fair use defense, when their version of Java is technically incompatible.
Then why not make any scientist who discovers any very important drug or therapy into a billionaire. If they are motivated the same way corporations are, then that should super motivate them produce more drugs faster. In fact why don't universities work the same way?
Because we all have a common ancestor that lived not that long ago[0]

0. https://en.wikipedia.org/wiki/Mitochondrial_Eve
> If anyone finds the document that highlights this, I'd be grateful for a link.

probably this one : http://www.vpri.org/pdf/m2010002_lobjects.pdf ?
Which drugs are produced by startups? As far as I know most drugs are produced by massive incumbents. The cost and the regulation is too much to do anything else. And as far as I know those incumbents are not turning their researchers that research those drugs into millionaires or billionaires.
Xerox WorkCentre 7855 Driver Printer Download
You also need to care about velocity when using splines as trajectories. In general, if you sample a spline at a constant delta-t, your speed through the world won't be constant.
> And why should the drug company itself get to determine the price, with no upper bound?

Because they took the financial risk to develop the drug.
I developed a similar product a few years ago.

http://lingomill.appspot.com

I would love to connect with you. The product uses subtitles and vice video segments to teach people a language. Dual subtitles are the key.
I'm with you. The sheer amount of human error in the medical field that causes death and injury is astounding [1], and I would gladly put my life in the hands of a capable machine instead of a fallible human if given the choice.

[1] http://www.futurity.org/medical-errors-deaths-1157152/
By that logic, the Linux ecosystem should be paying a handsome sum to whatever litigious shadow is left holding the UNIX IP.
It's a daily newsletter ("Money Stuff"), not an article. Agreed that it's a weird thing to post on HN.
This article is pure fluff, but I started the book recently myself and it's pretty good so far.

By the way if you are interested in SEALs the book "Breaking BUD/S" by DH Xavier is excellent - contains a lot of lessons for life in general. Don't be a blue falcon, for starters.
Likely because they are already working without all that tech. Fortunately, that means that around 50% of the world population will cope just fine :P
I'm not the inventor of protobuf, just a guy who rewrote and open sourced it. My rewrite did not change the underlying encoding.
Google the article to get around the paywall.
A Way to Deliver What Your Clients Expect
When you say "we pay the market value" and "give to the public for almost nothing", "we" and "the public" are the same group and therefore it makes no sense to make the distinction.

Unless by "we" you mean "the wealthy" and "the public" you mean "the poor", in which case the increased tax that has to be set up for that will just be reverted into the cost of the service/good provided by the wealthy, the wages of their employers, or turn into capital flight, and so forth. In short, you're basically taking money from other areas of people's lives and making them put it into health care. Which could be achieved by themselves by saving, if that's what they wanted to do.
Qaddafi did a bunch of other stuff too. Not sure the currency was a big deal.
The reason they designed SIP was partially to prevent anyone from replacing a binary with one of their own.

Because of the way that they have put in those shims, you can - without being root - install a binary (or a shell script) in a user directory that acts as if it was another program - the example I used is git.

(Interestingly, they chose to use a purpose built library to do this. Their git shim literally just checks an environment variable and calls on a library function to execute xcrun. I do wonder why they chose to write a program in a compiled language instead of using a shell script. A passing thought was that they didn't really want to publicise what they had done because they knew most BSD fans would probably throw them brickbats... but then again, Apple seem to be fans of binaries so it was probably not done to obfuscate anything...)

When you say that someone who is able to change DEVELOPER_DIR or install a fake xcrun is already in a position to do whatever malicious act they feel like, then this is precisely the reason why Apple implemented SIP. (I am curious why you think they prevent access to those directories even by root though...)

A big part of SIP is preventing the end user from typing in their password to give a malicious program access to replace certain binaries installed in the /usr/bin directory (and a few other locations). So basically they don't want git, or any other program, to work in a way they didn't intend - i.e. They don't want malware authors installing a riot kit by replacing binaries.

In essence, this is what this is doing. The main difference here is that instead of them needing to be root, they just create a directory, create a small script update an environment variable and optionally tweak .bashrc as the user and they have effectively added a wrapper to the XCode utility. With no need to elevate privileges.

I'm sure you can see that is problematic?
Ok, that makes more sense. So, I modify the question to be U.S. workers threatening mass suicide by gun or whatever with a good number at one plant over time. Then, the plant starts taking preventative measures against various suicide equipment instead of investing in working conditions.

This actually has more odds of happening.
Hi. I created this package. It allows one to run an extremely secure tor relay on almost anything. The package is very easy to use and seems to work pretty well. I've been running the first of its kind "in the wild" as an exit relay for a week or so here...

https://atlas.torproject.org/#details/FD76CE423F64853C402EAC...

And it was officially merged upstream today here...

https://github.com/rumpkernel/rumprun-packages/commit/0171d4...

Running tor in a rump unikernel provides a single application, single address space image, with bare minimum necessary support drivers, that can be run portably on pretty much any hypervisor (or even on bare metal).

If security is a concern, you would be pretty hard pressed to run a more secure tor relay. This doesn't even have a /bin/sh, for example. There's precious little available to be exploited here, even should a tor exploit be found possible. Odds are, even a major tor vulnerability wouldn't do an interloper very much good in this case.

For background infomation, see...

Tor

https://en.wikipedia.org/wiki/Tor_%28anonymity_network%29

https://www.torproject.org/

Rump Kernel

https://en.wikipedia.org/wiki/Rump_kernel

http://rumpkernel.org/

Enjoy. :)
What is the fair use ? To topple a monopoly? Or interoperability on Linux - which is a not-intended-for usecase.

Becaiy Google can pull the same defense - interoperability on Android. If Google loses, then it's going to be hard to get something like this off the ground again. In fact, every "porting" project is in danger.
I live in the U.S. if I didn't mention it. Here, we differentiate between the rights of the public as a whole and private individuals. Businesses and I.P. tend to be a form of private property. So, "we" the public can't take what "we" consider private. That's a contradiction.

In this specific case, it's the public paying money to private parties for their property to move into public hands. Then, that public property is manufactured to be distributed to the many, private parties in need that constitute the general public.