skysight-inc/HackerNews huggingface dataset:
This is amazing. The unfortunate thing though is that the effectiveness of cyclodextrin on NPC (versus atherosclerosis) might not hold up to scrutiny - I remember the NPC finding when it first came out almost a decade ago (worked in a lab that was interested in NPC) but more recent experiments have thrown the result into question.

It's kind of strange that this hasn't been proposed before - when you buy cholesterol for scientific experiments, it's often encapsulated in cyclodextrin, that product has been around for a while.

[edit:] found this http://www.tandfonline.com/doi/abs/10.1080/10717540050120205... so someone has investigated it before, at least.
If we succeed, we'll control the world's money supply. Along the way, we'll likely use a small, publicly-disclosed portion of the investments we receive for salaries and other expenses. We'd switch over to spending only GD as soon as is reasonable.

Our investors earn pre-determined returns on their Future Gresham Dollars (see other comments), so they make money no problem.
Yes. Ideally I think what I need is a co-founder who specialises in Sales & Marketing so that I can be free to look after the technical side of things, and they can handle the legwork of talking to prospect and recruiting customers.

I don't have anyone in mind, and I am hoping that this process will help with that.
I appreciate the nuance of your argument. It's a good point in general, and I personally don't fit cleanly into any existing party.

That said, I think we can reasonably propose that most of the sound and fury over the ACA was political theater. Mitt Romney wasn't decried when he passed a nearly identical law in Massachussetts. In fact, the RNC chose Romney to run against Obama in 2012, so it clearly didn't hurt him much.

Ask yourself this: if John McCain had beaten Obama in 2008, and he proposed taking RomneyCare to the national level, do you think he would have drawn the same kind of criticism from republicans as Obama did?

Don't get me wrong, I'm not saying this is a republican problem. Democrats probably would have been furious with McCain if that had happened. They likely would have decried the lack of public option, and they would have called it a massive hand-out to private insurers. Democrats are not any better. They only supported the ACA because it was backed by their guy.

Obviously I'm speaking in blanket statements, and there will be individuals that this doesn't apply to. However, I'm pretty confident that these statements are true in the average case.
I'm not the one you're asking. But there are some things that are pretty clear, not just "I think my boss is".

- Unreasonable demands (be available 24/7, when that wasn't clear up front or isn't a normal part of the position).

- Stabbing you in the back to make the boss look good.

- Verbal (or even physical!) abuse.

- Lying to you.

Note well: No resemblance to my current boss, and very little to any boss I've ever had.
> Typical treatments include statins and other cholesterol-lowering drugs, which are not always effective, particularly when patients don’t adhere to doctor-prescribed, low-cholesterol diets.

Must an otherwise good article perpetuate the tired bullshit about dietary cholesterol.

A piece of white bread topped with sugary jam (optionally on top of margarine) is a low-cholesterol snack.

Just because cholesterol shows up from what you ate doesn't mean that, say, statins aren't working; maybe you're just throwing off the method by which their effectiveness is indirectly gauged.
Why Invoice Follow-Ups Are Bad for Business
I am not familiar with the geological features of the Netherlands, but much of the Florida coastline is formed from porous oolitic limestone, meaning you can build as many dikes and dams as you want, and the water will go under them and appear to come up from the ground on the side where it is not wanted. This is why so many coastal wells here in Florida have such problems with saltwater intrusion.
ServiceStack Plugin for event-sourced systems using EventStore
I'm not saying this is your motivation, but when it's a proposal to the housing problem is framed as "Let's Fix San Francisco" it feels like the proposer believes they must live in San Francisco, especially when the proposer isn't a native San Franciscan. It feels tribal, and this issue is extremely tribal, and anyone who appears to belong to a specific tribe chimes in with a "We need to fix San Francisco" undoubtedly people from other tribes chime in and complain about how that tribe is the problem and the conversation usually devolves into name calling at some point.

When the proposal is a bit broader, i.e. "Let's fix the Bay Area", then, at the very least, it doesn't feel like a claim is being made on San Francisco by a specific tribe.

More than anything, it's the tribal nature of this issue that really sucks and it really stalls the things for everyone.
Isn't this just what the OSI model does, but at the application level?

Well, to be fair seems like one side talks like for instance 802.2 and the other in X25, with a software layer in between --adapter pattern?

Can't believe such patent was granted.
So a URL of JPEG file put in 'img' tag is infringing and the same URL put in 'a' tag is not? Sounds rather silly to me.
I think he means the rise of commodity cluster computing, a la http://static.googleusercontent.com/media/research.google.co...
Deep reinforcement learning lecture series by DeepMind's David Silver
The problem is no one really uses apps anymore. Especially to view a website when you already have a mobile app that does that for you (your browser). This feature is 3 years too late in my mind to be a needle mover.
Is AngularJS still a good choice for new projects?
If you were staring a new project today, would you start with Angular 1 and plan to migrate to Angular 2 later, or go straight to Angular 2, or just use React or some newer framework?
U.S. failed to show how MetLife is “too big to fail,” judge says
Dev? I wouldn't think so. Autolayout and size classes handle most of that.
Agreed. I'm really impressed by the professionalism shown by all members of the React ecosystem. Just the other day I had noticed a org member of the reactjs org (houses react-router, redux, etc) who was acting very unprofessional and expressed that it was a turn off seeing official members of the org basically telling a issue reporter/discussion was "annoying them" and Ryan Florence stepped up and said he was not tolerating that and even reached out to me on Twitter apologizing and saying that they do not condone such tones.
It varies. I frequently see them listed for sale in the DFW area.
Because eastward launches net you more delta-V, you also benefit a lot from not having anyone to the east of you on whom to drop spent stages.
I would like to see those videos actually.
Tweaking the software in autopilot could cause it to kill you and anyone else on the road. For example, you might accidentally make it not return control to the driver when it can no longer navigate or cause it to accelerate out of control. It isn't clear to me that increasing horsepower or changing the wheels is as significant. There are a bunch of common modifications that are outright illegal like high/low-riding changes, emissions, lighting, etc. though it is on a state by state basis in the US.

http://blogs.findlaw.com/law_and_life/2012/07/the-top-5-ille...
let me fix
It's nice, but remember that Russia launches from 45N, so it isn't that critical. The boost is 880mph for KSC, vs. 790mph for Denver vs. 710 mph for Baikonur. The deltas are only 100-200 mph, vs. the 17,500 mph needed for orbit.

The worst case is Israel, which for geographic and geopolitical reasons has to launch to the west instead of east. Even that's only about a 30% penalty in payload. https://en.wikipedia.org/wiki/Israel_Space_Agency#Palmachim_...
I mostly enjoy the syntax. Kind of hate that they made parentheses for function calls optional, especially since no-parentheses has ambiguous cases that behave weirdly (like with chaining syntax). Should be enforced.

Also, all the different import-related keywords are pretty confusing. Maybe that's improved though
Initially we are beginning with quinquennial term lengths with a fairly conservative price structure. However, our model is being designed with the end-state in mind.

In our end-state, we intend to have full flexibility on any lever possible.

For example, say you have the option of covering your education in return for 5% of your income for 20 years. This may be equivalent to 10% over 10 years, or 20% over 5 years (please note these are purely for illustrative purposes and not discounted/run through our pricing model).

You will have the option of having a sliding scale for income sharing %, term, etc. It should look near-continuous rather than discrete. Sliding one parameter will certainly drag the others but we will provide recommendations based on what the user's financial needs are.

--

We have an exceptionally data-heavy focus. As for adjustments, this model will take inputs (e.g. GPA) such that when a student does well in class, they can "refinance" to perhaps take off a basis point or two depending on the model output which could be significant over the course of repayment (a la "Get an A in Organic Chemistry and save $120 on average over the course of your repayment period."). This can also apply to when a student acquires an internship or their first job which gives an idea of starting salary. More data will allow us to more accurately predict their future earnings potential. Realistically, these adjustments can apply to anything with a statistically significant impact on a student's future earnings potential.

We believe this will allow for students to feel a sense of control over their education financing.
I've recently been coming across some strange message sync issues with using the desktop client on two different computers. It seems like they'll go out of sync, and not all received messages will arrive. Sending works sometimes, but I won't see the "received" checkmark. Re-pairing isn't enough to fix it, I need to delete the Chrome app to clear the history and re-pair. Anyone else coming across this issue?
>> I wonder if it could be possible to have an OO language with an automatic Erlang process per object, automatic immutable data (just don't let reassign values to variables, like Erlang), and a way to define supervisor trees.

Is it possible to implement it using the metaprogramming features in Elixir?
When it was at an earlier stage of development, I tried out porting the Chome App over to NW.js (formerly node-webkit). It was easy enough and the result worked fine. I'll have to see if this is still the case.
Why We Built the Record
Any programming language can do IPC, but Erlang/Elixir is the only language I've seen that makes it really easy. Erlang IPC is transparent whether you're sending messages between to local processes or remote processes. Most languages have trouble with local IPC (usually because of race conditions in data). Every other language I know of, including Go, needs custom code to handle remote IPC.
We don't do any qualifying ourselves. We assume that the external consultants are already established, and are just looking for a platform to help their existing clientele. (We actually have a couple of consultants using HR Partner for exactly this purpose now - in fact, a couple of others have asked for a 'white box' edition that they can brand for their clients).

As far as insurance, we assume that their existing practice insurance will cover them (similarly to how an accountants malpractice insurance will cover them if they make a mistake entering data into their client's accounting software).

That's why we don't actually do things like calculate the leave etc., because of the local rules and regulations - we simply cannot take into consideration all the global differences.

Instead we are just a repository or all manually entered data, and we have to assume that the data entered is good and legal. If not, the liability will have to rest with the person entering it.
Can you tell me where the constitution gives the president "broad powers as to national security"?
Self-driving trucks just made their way across Europe
Ugh. So disappointed.
very excited to see Tempe at the top of a patent, that whole area deserves some recognition.
This link indicates a March 24 deadline in the FAQ. It should be updated? https://fellowship.ycombinator.com/faq/
> but others are allowed to create evolutions of the universe

No, I disagree. It's Blizzard's right to decide, who is allowed to do it. Only Peter Jackson was allowed to create movie about Tolkien's universe - and it was right of the author, without any doubts. It's the same case.
Well I asked because googling showed me very little. Basically Greenwald and Snowden used Cryptocat during some online interview.
> A highly populated area or industrious zone might get a rating that only a flood every 10.000 years is acceptable, while for some rural areas may get a rating that a flood every 300 years is acceptable.

Or until a king decides to flood the country to stop an army from advancing.
Fair enough. However, my paid work for the past several years has been as a frontend developer, and consistently, the browser that has held us back from adopting newer features has been Safari. I'm very happy to hear they have better/very good ES6 support coming up, I'm very glad to be wrong there.

And hey, for whatever reason, Apple has earned my eternal gratitude (and my consumer dollar) over the past few months by being one of the only entities in this country capable and willing to stand up to government bullying and surveillance. Web standard are great for me in my job, and I believe they're important for the future of online communication. But standing up to government overreach is of critical importance to all of us. I'm an Android user myself, but wife uses iPhone so I'm already getting ready to buy her a new iPhone 7 when they come out.
>>If you don’t think about security on a regular basis, this probably looks normal.

Can someone help me understand if this is an assumption or a status quo?

Then, what does storing this information gain you from an app owner perspective?
+1 to this. High-quality code from @mwiencek right out of the gate, and he was super responsive to my comments when I asked for changes. We're really grateful for the contribution.
I wrote up an article about probing for culture in the interview [0]. Here's the tl;dr:

It's really hard to pull out the truth sometimes. Those that aren't looking through rose-colored glasses are outright lying to you. No company sends disgruntled employees to interview.

It's important to figure out if the company has a plan for you. If the plan seems like "Change everything, but without any power to do it", book it outta there. It's totally OK to ask folks what they think about management. Again, rose glasses, but folks usually don't have a cached answer for this one so you could catch them by surprise.

I find one of the biggest indicators of "Do I like this place" is how disagreements are resolved. Ask about those. Press for details, don't take sweeping statements for an answer. Actual examples are best.

Finally, lots of folks make bad decisions right out of college. I certainly did. Very few folks will hold it against you if your first job is a short one (~six months).

If you've got any further questions, contact info is in my profile. I can run a mock interview if you're up for it. Hope I helped!

[0] https://rkoutnik.com/articles/Questions-to-ask-your-intervie...
Google may be considering Swift as a ‘first class’ language for Android
It is specifically because of the preemptive scheduling that I find it worthwhile to write code that would otherwise be better suited to a different language in Elixir.

Numerical and statistical stuff, for example, is never going to be performant--but that's okay, because I'd much rather have a whole bunch of slow actors making incremental progress safely than a couple of blazing fireballs that could take down my system using NIFs or whatever.
Treasury bonds?
Angular two lost me.
Meanwhile I live in Downtown Albuquerque for $770 a month plus < $100 a month for utilities. Maybe not as developed as downtown San Francisco (far from it actually), but there's still more breweries, music venues, coffee shops, and restaurants than I know what to do with.

I can't take this solution seriously as long as I pay almost the same price for a loft apartment with exposed brick walls, bamboo flooring, a washer and dryer, and a number of other nice things that I'm too lazy to list. I especially can't take it seriously knowing that there are communities practically begging for people to reverse the trend of the rural exodus.

Granted, the tech community isn't as strong here, but you'll still probably figure out a way to make things work if you've got out-of-state connections and don't mind dealing with our slightly confusing tax policy.
> Well, I believe IQ tests during an interview process is illegal in the US.

Only if they can't show it's materially related to the ability to do the job.

When I first started working for the IBM LTC, IBM had an online aptitude test as part of their application. The results directly determined both whether you got hired and how much you got paid.
I think part of what made home searches annoying in the colonial era was that they were disproportionately applied to the political opponents of the colonialist status quo. We see those concerns reappear in the modern day in the form of, e.g. loveint, and presumably other pernicious politically motivated investigations. The federal code is so broad as to be able to be used to harass anyone for a legion of infractions at any given moment, so it is a reasonable threat.
vimdiff is a mode within vim to compare differences between buffers. It allows side-by-side comparisons like modern GUI diff tools by showing buffers in different 'windows' (vim screen splitting). You could also open multiple window in this mode to make vimdiff behave like a 3-way merge tool. It also has commands to pick hunks from different buffers into the merge buffer.
Ask HN: Do you work for/run a startup with private offices?
A while back I read the book version of Joel Spolsky's Joel on Software[1] and one of the many things that struck me is how he gives each developer a private office. He's written about it and been written about in various places [2, 3], but I would like to hear from other developers or people who run tech companies – especially small ones including startups – whether they do this, too? If so, can you share a bit about how it goes down? Do people like it? Does it help attract smart people?

Thanks!

[1]: http://www.joelonsoftware.com/BuytheBooks.html
[2]: http://www.joelonsoftware.com/items/2008/12/29.html
[3]: https://blog.stackoverflow.com/2015/01/why-we-still-believe-in-private-offices/
I'm glad I'm not the only one that realized this. Not that I actively go around trying to find other people though.

Even bad geocities pages were unique and interesting. I haven't come across anything that's like that in so long. It seems like an endless cycle of content aggregators and the usual news website. There's really no reason to actually explore or any easy way to do it. Might just be me though.

Even myspace allowed you to edit the CSS and pretty much do whatever you wanted with your personal page. Now all we have is Facebook and the actual information isn't important at all. I rarely even bother visiting people's pages nor have I updated mine in so long. It just doesn't matter for the most part.
When I interviewed for my current job, the whole (4 person) team did the interview at once. Several times they talked smack to each other in the interview - not mean, just having fun. Well, I can enjoy that, so I talked a bit of smack to them during the interview. They hired my anyway.

When it's not done in malice, that can be an interesting indicator. It means that the people on the team trust each other - trust that they can say such things and have it received in the right spirit, and trust that the one saying it isn't saying it in malice.

I wouldn't make this the only indicator, but it's an interesting data point...
Note that "better" means better for some kinds of things. Preemptive scheduling has a cost, just like running a program on top of, say, Linux costs more than if you coded it specifically to run on the chip itself with no OS.
Well then, do better and don't look back.

There is no shame in taking a first job out of college and realizing it wasn't meant to be.

Working at your age should be akin to dating...you should have no guilt or issue with realizing you acted without having complete information and perhaps jumped into something that wasn't, in the end, right for you.

Why not start actively shopping a resume and talking to colleagues your age to see where you could possibly land next?

Good luck, and keep moving towards a better tomorrow.
Discover, Enjoy your Facebook videos like never before
If you were the interviewer, how would you answer that question yourself?
Query. Is the borking of RSS feeds last couple months related? It was done so poorly(still borked despite assurances contrary)? Would be quite a convenient way to herd a bunch of RSS users to sign up PDQ to keep their TIL & ELI5 fetishes uninterupted.

I'm afraid I did the opposite, however. I don't need a new app, and again contrarily, I don't need a new feed reader. My worthless trivia supeepowers are indeed in decline. Meh.
Has Facebook removed the potentially dangerous patent restrictions?

https://news.ycombinator.com/item?id=8985541
Well, the notion that text can be safely treated and manipulated as binary data and still make sense is what doesn't work here. It's the wrong tool for the job, then. That's kinda the same as reversing text byte by byte and complaining that all diacritics are wrong.

Yes, cat comes from simpler times, but if cat cannot be changed for compat reasons, then it should no longer be used to concatenate text files. At least if the result is somehow important. Text and binary data are simply two very different things and both need to be processed accordingly. Sure, there are a bunch of other operations that are immediately recognisable as not making sense on text at all and superficially concatenating files is not one of them, but in my eyes that's a bit shortsighted. You can safely use methods for binary data on text iff you know exactly what your text contains and that the operation is safe. Otherwise you may mangle things.
Ask HN: What equals to unix pipes in the web world?
I like the simple but powerful concept of unix pipes. Is there anything equal for the web world? If not, wouldn't it be worth to think about or even develop it?
Did you try the openjdk that is bundled with intellij idea eap builds? It is Java 1.8 with quartz font rendering. I use this version since December last year to run AS without any problems.
Why not make AlienBlue the official reddit app? They bought it! This is a very strange course of action.

This is one of "Things You Should Never Do"
http://www.joelonsoftware.com/articles/fog0000000069.html