skysight-inc/HackerNews huggingface dataset:
From Reddit:

> Cello was designed to allow for logical development of large DNA circuits from a general functional description.

> You could say "I want a cell that can detect arsenic, mercury, and cadmium in water and provide different color output signals. Also, those output signals should correlate to the concentration of metal detected." Cello would look through its database for promoters that detect those metals and genes that produce chromophores or fluorophores. And then it would look for various modulators and feedback loops to make sure the amount of color produced is measurably relative to the signal. It would produce possible combinations of circuits that could have the function requested (different gene order, different orientations, different modulators, etc.) and the assembly plans to build those in the lab so they can be tested.

> It's easy to mix and match a few promoters, even a half dozen or so. But once you start adding a large number of small circuits together, it simply gets too complex to scribble out the permutations on paper.

> Much of the credit for this tool goes to Prashant Vaidyanathan at Boston University, the forth author on the manuscript who did a large portion of the coding. It's a joint initiative between Boston University and MIT, initiated by the CIDAR lab at Boston.

> Source: I just graduated from this group.

https://www.reddit.com/r/science/comments/4dbvmr/mit_develop...

(To clarify, I'm not the author of this summary, just found the post. Reply there if you want to get in touch with him/her!)
I think the mirrored thing is mostly for assets -- js, images etc.

For most smaller websites it's one server somewhere (for the majority of them actually co-hosted with other sites in a single location/box).

And for most large websites outside of the very big (e.g. FB and Google), it's at best a few locations around the world, e.g. e.g. US east/west/mid, 1 in Europe, one in Asia, etc, and often even less. So the distances involved do get large there too.
Attackers Flock to Medical Device Honeypot
Zapier first-draft before it became the Zapier we know
Deep3D: Automatic 2D-to-3D Video Conversion with CNNs
Cool stuff! Admittedly it took my a moment to figure out the particles signified wind gusts, but once I figured that out the rest was straight-forward.
http://s2.quickmeme.com/img/82/8273ea559a925938b1fefd3ee7444...
You don't understand. "Supercharging" means hardware. It takes additional charging hardware to be compatible with a supercharger. On the Model S supercharging hardware was an option. I hope you are right but at this point it's still unconfirmed.

https://www.reddit.com/r/teslamotors/comments/4dc6rs/officia...
No, because that only applies to forking a project within the Github UI. Nothing is stopping anyone from cloning a project and pushing it to their repository.
> passively learn without effort

Getting taught by a teacher or helped by a teaching assistant is not 'passively learning without effort'. It is getting the help you need at the time. The job names literally include the word 'teach' - it is their job to teach you.

Yes, self-learning is a part of any degree, but sometimes people need help. Sometimes people learn more quickly and easily with help, and that's why they pay someone to help them do it.

I, personally, did not need or want that help. If I had, however, I was paying for it, and have the right to that education, as does everyone who does so.

You may not have said 'only', but you did say people shouldn't expect to have a degree given to them after being given an example of someone asking for help a couple of times. You implied that people should never need to ask for help, and should instead self-teach.
YMMV. For me, I don't really care about the nuts and bolts of engineering (I know others do), it's just the vessel in which I take to the vast and endless sea.

FWIW, I have a totally unscientific gut-feeling that feeling cool about the process and the tools (rather than the outcome) is a slightly male-heavy preference.
Zelda 30 Year Tribute
I struggled to find a single short description for activities that can easily saturate a modern PC's processing power and I/O, but I couldn't really. Let's not get hung up on naming here.
I don't personally use Grunt, but your attitude is highly commendable.
I am going to assume your comment is a serious one.

This case isn't a "trial by media". What is happening is that several investigative journalism groups are getting together to examine data acquired through a leak.

The examination may lead to lawsuits, criminal investigations, and legislative action, but is by no definition a trial.

The questions asked as a result of the examination of the leaked information may lead to uncomfortable questions in private and in public.

At this point, who is being accused of wrong-doing?
I wonder if you can make a latch? It means allowing combinatorial loops:

wire q, q_bar;
assign q = !(q_bar || reset);
assign q_bar = !(q || set);

If I'm understanding this, I think the answer is no. The output signal is a concentration of a specific protein and there is no way to eliminate the protein once you have it.
Twitter wins rights to stream NFL Thursday night games
Simple 230V AC charger take 24hrs to charge a car...
"what, exactly, is so terrible about most of these little stories."

That's exactly the point. Everyone hears this sort of thing and mistakenly infuses it with some significant meaning when really, it's just developers talking to developers.

Whether that was the original OP intention, I dunno, but it's the best lesson here.
https://news.ycombinator.com/item?id=10543908
On one hand I agree that getting women interested in CS earlier will help, but it also seems unfair for introductory CS courses to penalize people who are new to CS. One solution some schools have implemented is to have multiple entry points, so that the experienced students can start off in more advanced courses without biasing the other truly intro courses.
To me it is a combination of repetition and a confusing flow. It feels like it the author kind of discovered the interesting bits as she/he went. But I don't want to be a Criticizing Craig, so here is a (hopefully helpful) breakdown:

“When the voice coil is driven at the resonant frequency of the spring, the entire actuator vibrates with a perceptible force. Although the frequency and amplitude of a linear resonant actuator may be adjusted by changing the AC input, the actuator must be driven at its resonant frequency to generate a meaningful amount of force for a large current.”

Ok, got the basic principle and the key constraint (resonance) in the first paragraph.

“The voice coil remains stationary inside of the device while it produces a vibration and presses against a moving mass. By driving the magnetic mass up and down against the spring, the LRA as a whole will be displaced and produce a vibration.”

The first sentence feels like a repetition of the basic principle, but I get that (together with the second sentence) there is a subtle point being made: the whole assembly vibrates. I'd cut the first sentence or make the comparison more clear: “Although the voice coil is stationary within the LRA, … the LRA as a whole moves.”

The speaker comparison is good for illustrating the resonance constraint, but the conclusion simply repeats rather than expound on the principle. Leading the reader can make the implicit connection more obvious and avoid repetition: “While speakers can be driven at arbitrary frequencies, the physical spring within an LRA imposes a …”

“Rather than directly transferring the force produced by the voice coil to the skin, the device optimizes for power consumption by taking advantage of the resonant frequency of the spring. If the voice coil pushes the magnetic mass against the spring at the spring’s resonant frequency, the device can produce a vibration of higher amplitude more efficiently.”

This paragraph reintroduces resonance, but as an efficiency improvement. It feels repetitive, but there is an important point here that is left as a connection for the reader to draw: Offset rotating masses don't use resonance and draw much more power. I would actually use this in the leader. Instead of introducing resonance as a just a component of the system, make it the key. Instead of “that is DC and this is AC” (the impression I got from the first paragraph, lead with “that uses brute force and this uses a cool property of spring systems: resonance.” The latter is much more interesting, and can help reduce the repetition.

“Although the frequency can be changed, the LRA will typically be operated within a narrow frequency range to optimize its power consumption—if the device is driven at the resonant frequency of the spring, it will consume less power to produce a vibration of equal magnitude”

Repeating the basic principle again. Get rid of this and get right to the next sentence about how you can use a fixed frequency/varying frequency.

Hope this helps!
InversifyJS 2.0.0-alpha.8 release
>For a global giant its very very poor

Not really, as that's not how they roll. They usually have small market share, but of the highest end / largest margin part of the market.

Those 5% can yield like 30-50% of the profits of the whole smartphone industry in India, and 80% of the high-end (more expensive) smartphone profits.

A company that only targets the high end of the market should be compared to other products/companies in that, not the overall.
Entrevista a Miss Azure Stack, la nube híbrida de Microsoft
Granted my domain of knowledge is more aligned with the recognition side, i'm pretty sure Viola-Jones has been replaced as 'king' with more robust approaches to detection. Here is a paper published just last year in CVPR:

http://www.cv-foundation.org/openaccess/content_cvpr_2015/pa...
At Tesla, Software Takes the Driver’s Seat
Yes, it's a part of their registration process and you cannot bypass it. :/
You need to learn more about companies outside of the US/Europe.
Maybe they had to take the whole week off because they were required to come in instead of rest on that first day. Maybe it would've only been two days otherwise.
Honestly there isn't much point. You can do the same stuff on grunt, gulp and apparently webpak. Personally, to avoid the extra mountain of dependencies, my newer projects just use scripts now to do building and I just simply reference the same depdencies grunt and all wrap. It's quite easy.

Honestly there is some utility to using these build systems as they make it a tiny bit easier than just writing a script...but that's about it. It's really easy to write your own scripts to do the same thing with barely any extra code.
Oh, now that I complain publicly about it I finally get an apology, instead of passive-aggressive "it's all your own fault really, stop caring about PII and just unsubscribe" mails from your staff.

You might want to think over how you communicate with your customers. Customer privacy isn't something you can just shrug away.
I mean, regardless of the justification, this is not a very professional way to talk to a fellow colleague. Something like, "it's important that this server is configured correctly, so I think it would be better if I took care of it myself, if that's ok with you" would have been a lot better.
ok thanks for the explanation =)

but why? I guess to improve the "readability" of the map to the human eye?

[edit] Never mind:
https://en.wikipedia.org/wiki/Vertical_exaggeration
Since you're new you might be able to get the time they have in mind by asking 'what are your expectations for this'. (keep in mind some managers aren't good at estimating development time or might try to low ball the time to see how productive you can be)

Other than that every task/spec is different. I would review the task/spec then get back with them with an estimated range of time. 4 to 6 hours/4 to 6 days and tell them you'll update them on your progress as it's completed.

Once you're working on if things are going faster complete it/test it/review the spec/double check it and then present it as things went better than my estimate.

If things are taking longer, go to them early with what is completed and an outline of items that are taking longer than your estimate and have a new estimate ready for the time to overcome these challenges and complete it.

I would say relax, be a good listener and communicator, re-read specs/requirements and make sure you're complete/thorough in your work keep them informed and you should do fine.

Since you're new try to find someone you can trust, to be your mentor, show you the ropes, help you out, bounce ideas off of, give you the lay of the office/land.
Yes, but usually this is not a problem, because rollbacks are rare in production.
Brunch is great but last I used it there was no support for NPM modules. So I built Parched on top of Gulp to mirror the Brunch experience.
Yeah, I dunno, I think you missed the point. The majority of what I read there was pretty basic. This is how masculine (note, I didn't say male) professionals generally talk to each other. Is it the most optimal way? Probably not, but there is way way way worse.

Like, you know, yelling at someone in a meeting, swearing aggressively, etc etc.
Yes, well, the hammers are hundreds of dollars a piece so we have to make due ;-)
Try rusty-tags[1]. It's just ctags that gets run on all your dependencies too.

[1]: https://github.com/dan-t/rusty-tags
What water is that?
In a sad turn of events in Scotland, Barr moved away from reuse of bottles for Irn Bru and its other drinks at the end of last year: http://www.bbc.co.uk/news/uk-scotland-glasgow-west-33985022

As a kid, I collected bottles from wherever I could find them, and returned them to get more juice, or stickers, or trading cards, or sweets. Some shopkeepers even gave you the money back in cash, rather than making you use it to buy something from them, and those were the preferred shops at which to return the bottles. When I visited Canada with family as a teenager, I diligently returned all the plastic bottles and cans I came across for the 5c refund.

Nowadays, I live in a poor part of town, and right up until Barr stopped the refund, I would see kids going around picking up Barr bottles and returning them. Whilst they were doing that, they'd usually (unprompted) pick up other bits of rubbish and drop them in the bin too, effectively cleaning as they went.

That 30p refund might not mean much to most people, but to some people, it means a lot --- and as an unintended benefit, it encouraged a certain conscientiousness and pride in the place they lived. I'm sad that they stopped it, and that's without even considering the environmental impact.
How large was the previously mapped network? It seems that cortical neurons are the most common neurons examined for this sort of thing. $18m seems small, especially when compared to the $1b that OpenAI has raised.
Jesus, I can't think of a better example of "1st world problems." Boo hoo.
I'm super-sure you are the outlier. Because Gordon Ramsey throws tantrums all the fucking time on his stupid tv shows and people believe he is the best chef in the world still. In fact, it seems Gordon Ramsey's reputation for being a master of his craft has only increased for all the times he has gotten angry on tv.
Effortless network response logging on Android
International trade requires operating companies in many jurisdictions.

Even something as small as a single person consultancy that has clients in 2 countries (Canada/USA say) are frequently benefitted by having entities in each location.

Those entities also need money, frequently in each location, so holding cash in banks in each location is also beneficial.

Having offshore corporations is not evil, its just mechanics.
I built a football betting algorithm and constantly play with that to improve the accuracy..

Generates a very healthy income!

betalyst.com
I think that argument holds up a lot better in countries that have (relatively) impartial and transparent rule of law than in countries that don't.

In other words, it looks like this is having real and immediate consequences in Iceland, but I wouldn't hold my breath waiting for Vladimir Vladimirovich or any of his cronies to be indicted.
Life is not roses, and people should learn to have thick skins.

That said, saying "Don't touch my server!" is not at all abusive, especially if there's a history of people messing things up they have no business touching.
This is very cool... nice work! (p.s. to get the sword, just go into the black opening above your character at the beginning... I wasted way too much time to discover this)
Agreed, but if you don't get that, you shouldn't take it personally. Which I hope is what the OP is trying to say.
Really? I don't drink coffee, but do drink tea, and I'm pretty sure that people drink them for reasons other than the raw caffeine content per ml.
UI/UX 10 days?

Yeah right.. The recoloring of the arrow itself I'm sure took 10 days...

I'm working with a bank right now trying to just get them a UI for an authentication page.
We've struggled 2 weeks trying to figure out what the hell they want for the FAQ page...
Between the design-spec they provided and where we are now, I'm not sure why they have designers in the first place..

Our first product was according to their spec, which they scrapped instantly and stated they expected X,Y,Z instead, which weren't in the spec (Page should have an accordion, the accordion should have buttons, all buttons should have certain looks and sizes. The spec didn't even have borders, much less an accordion and no buttons in sight..) and when we produced whatever they stated they wanted they threw out half of it and flipped things around (now the buttons shouldn't be arrows, they should be + signs that become - signs when clicked on...)

I'd hate to think what the UI/UX process is trying to get through multiple layers of governmental bodies....
Of course. There are some general lessons about communication that you can learn from these examples. But nobody will do the right thing in every social situation 100% of the time.

It's not that you don't have valid complaints here. It's that you've taken a huge number of examples that range from the simply ungraceful to outright exploitative, and combined them in one huge file that makes it look like you're seeking reasons for your grudges.

A good workplace isn't one that avoids mistakes and conflict. It's one where the team feels invested and supported in working through that conflict in pursuit of their bigger goal. That goal doesn't have to be some world-changing potential; it can just be doing good work, getting paid, and taking care of yourselves.
You also need to be more situationally aware and/or humble. I'm a junior dev, I probably should ask for permission or guidance before mucking around. That's life.
> you can find a market for luxury cars even in most brutal dictatorships

But you're unlikely to create a luxury car company in an unstable country.

> trying to establish a small business with stable clientele might be quite hard.

There are plenty of small businesses with stable clientele in Bangladesh, Haiti, Yemen, and pretty much every country in the world.

> "symbiotic relationship" is not a bad description of what is still happening.

I'm not saying it isn't. But you still can't have a large company in an unstable country, while you can easily have a fruit stand there. It is the large businesses that benefit disproportionately from the state.

> Startups - not so much.

Right, you probably need a stable country for startups, too. But most countries don't tax startups much anyway.
The new and used car markets are nearly separate. Few people set out to purchase a car open to both possibilities. If they were comparable then the prices would be more similar. Look at houses for an example of that. New and used houses tend to share the same market, and also tend to have similar prices. If you're looking at a new car and trying to see how it might sell, you want to compare it to other new cars.
going deeper in deep learning
Call Tracking Solutions – prove your return on investment
Q: How many IBM employees does it take to change the light bulb?
A: Don't know. But will cost $1M+. They will pay for the bulb.
Netflix Prize
Zero of those things fun, granted, but zero are scary. That's a total misuse of the word aimed at you coming off as sympathetic to women's issues.

FWIW, my mom, mid-50s, has been in tech since the '80s. She has complained of sexism. She also says the idea that tech is more sexist is a joke, and that her younger female co-workers complain a lot.
Progressive and customizable autocomplete component
To clarify, 1.6 is the first stable release since 1.4.2.3.

1.5.X was a development series.
I think your reply just confirmed that OP has a point. "Boys will be boys" is no justification for rudeness
Insignia: Progressive, Customizable tag input
3D-printing a structure with active chemistry
>our collaborative processes just because changes are staged locally first.

The keystrokes of ^H Backspace are not a "collaborative process". The idiosyncratic persistence of RAM buffers of a text editor is also not a "collaborative process". Why do you think "git commit" on a local unpublished repo is collaborative? I can only guess that it's because the word "commit" is in "git commit"? Well, syntax is not semantics.

>I'm very aware of what DVCS is.

I think many people with your position know the commands syntax of DVCS but don't actually grok the "draft work" philosophy of DVCS. Therefore you assign label of "collaborative process" to unrelated concepts such as the typing habits the programmer happens to execute on his laptop's harddrive. Unfortunately, the programmer persisting his editor's RAM buffers to disk happens to use the command "git commit" which distorts the thinking and causes people to label that action as "collaborative"!

The "pull request" and "merge" is collaborative. The raw "git commit" is not.
Yeah, I didn't pay much attention to it beside the day I bought the PS2.

Eventually I got hold of the PS2 Linux package, but getting monitors with sync on green wasn't that easy.
Interesting comments here on Fred's experiences. I agree with some commenters that more context is needed, but I think the key point(s) missed. This is about civility,tact,compassion, humility and communication. Civility is not something you innately have,but is learned (or not in some cases) and quite frankly many people do not know what that is. Tact clearly was not used in some instances. Compassion was lacking in the perceived arrogance and defensiveness shown. Humility can go hand in hand with compassion in realizing you are not the "shit".

Communication, or the lack thereof, can contribute to the situations that occurred and that too is a learned behavior and not innate.

I can empathize with the situations and it is always good to be aware as a way to foster your growth and understanding.
On a similar note .A more crowdsourced data website :
http://clientsfromhell.net/
PS:These are majorly designers ranting
> if I can't get a job, I am by definition a useless, surplus person

No, because you are a unique human being with your own unique value (yes, just like every other human being). Those aren't empty words: you're worth something.