skysight-inc/HackerNews huggingface dataset:
They're not. If you put a synthetic genome in to a cell that's just had the genome removed, that's very different then starting with pure molecules and building something that will boot.
Nothing about this is about hating Google. It's about basic human decency.
I came across this one on HN a while ago, and have found the recommendations to be quite good: https://play.google.com/store/apps/details?id=com.curated.an...

I wish Valve would expand Steam into the mobile gaming market. That would certainly help with the discovery problem, with frequent sales, user reviews, custom tags, and whatnot. Also in my experience, their recommendation engine actually works pretty well.

Obviously they'd have an uphill battle on their hands, as they can't distribute their store app on the Play Store, but the Amazon App Store seems to be doing decent so far despite that handicap.
Fascinating tech, but is it actually saving lives?
There are lots of quirky cargo cults creeping into the .NET world, especially since the growth of Nuget. I've seen a few projects with DI/IOC everywhere, to the extent that I expect to see a convention test that fails if the new keyword is used in a project.

And the stubs and mocks. I recently had to fix a beautifully tested piece of code where the developer forgot to implement the actual functionality. The proliferation of async/await and the idea that no self-respecting app can exist without a REST API layer also grate.

Cargo cults seem to move in waves, and the frequency of those waves seems to be ticking up of late.
> "We disagree with the CNIL’s assertion that it has the authority to control the content that people can access outside France”

Absolutely, and kudos to Google for fighting this ruling. This is an important dispute over jurisdiction, and it needs to be resolved sanely.
Creating an actual cell from scratch would be very difficult but not particularly compelling.

The synthetic genome gets "transplanted" into a host cell (in this case the M.capricolum baterium), from that point on, it "IS" the new organism and divides as such.

And anyway, there's a tremendous amount of stuff to study with "the platform" of a transplanted genome. Venter should probably get the Nobel prize twice-- once for shotgun sequencing and at least once (if not twice) for synthetic biology. These are huge advancements.
>It has nothing to do with censorship. In fact, the requirements of the Right To Be Forgotten are pretty clearly stated to ensure that anything that the public deserves to know or should know does not qualify for RTBF protection.

So ultimately, some body has to decide what does and doesn't qualify. We call that body a "censor" and their work, "censorship".
More amazing—a half century ago, the U.S. was undertaking some incredible public works projects.
Hey, Stencila developer here. Yes, I agree. I recently came across the Numbers app when I was writing this. I haven't used it but from what I have read it seems to have some really good ideas for improving the spreadsheet interface.
Every case is different. Contacting a lawyer is the best advice to avoid getting distracted. You will anyway, but try to delegate as much as possible. Some countries have special quotas in the H1B, others have the NAFTA, some founders might do E2, others L1s, etc. And all the knowledge from achieving this is a good line to start a conversation with other international founders.
The picture on Wikipedia's anti intellectualism page is from 1875, if that counts:

https://commons.wikimedia.org/wiki/File:Nast-intellect.png

Obviously the nineteenth century was okay with using intelligent people as the butt of jokes and in negative comparisons.
Ah les Francais. Show le Google our force. 100.000 EUR fine. Regardless of whether the decision is right or wrong, the real question is: will it work. Will they make Google and other companies submit with such methods?
Last time I did the math you have to order pretty regularly for the subscription to break even. I use instacart about once a month and just pay the delivery fee.
Dear NPM
Does CitusDb fit in olap analytical workloads to do aggregations on hundreds millions of records using varying order and size of dimensions (eg druid) in max of 3 seconds response time using as few boxes as possible - Or there are other techniques have to be used along with Citusdb? Can you shed a light on your experience with CloudFlare in terms of cluster size and queries perf?
There is also a bit of historical discussion on Wikipedia about this: https://en.wikipedia.org/wiki/Metropolis%E2%80%93Hastings_al...
Most of the world does this, it's standard traffic engineering.
Well but the husband works and lives in China, so it's natural to pay taxes there. I suppose wife and kids are supported financially by husband and she doesn't work, so why would they pay taxes?
https://news.ycombinator.com/item?id=11348893
Looking into the links you sent. Not sure if I am on board with "whether or not something is a public good is a matter of technology." I would say it is a matter of shared values and ideals. When you describe trains, you are talking about individual seats which are rivalrous, right? The train as a whole is a public good: it benefits everybody, has large positive externalities, and without subsidies it is not likely to be supported for profit. It is not rivalrous as a whole.
The fact that we don't have a couple operators instead of a driver for each individual train on BART is beyond me. Look at all the private companies (Magic Bus, etc) that are sprouting up because of how terrible our public transportation is.

BART essentially holds a monopoly on our transport. I believe their contract states even during a strike, new drivers have to be trained for 6 months before they are allowed to drive BART trains. There is absolutely no way that it takes 6 months to learn how to drive an AUTOMATED train. There should be public bids submitted from private companies to run on these railways, which would lead to better service and lower costs.
That was indeed the case.
The worst thing is companies buying water sources to build bottling companies. How can politicians allow drinking water to be privatized in some places is beyond any explanation.
We do. Look at the cost of the WTC PATH Station.
Do you seriously mean that France thus banned humans with allergies? It is false dichotomy. Completely fits pattern of blaming somebody else.

To the comment below:

"but allowing animals that spread dander everywhere makes the environment hazardous to anyone with serious pet allergies."

unfounded BS (sounds very similar to industrial bread producers propaganda 100 years ago about those dirty immigrants touching your bread with their dirty hands in their dirty bakeries). Until it is a sterile OR, the surrounding environment is full of living matter. Dog or cat in a cafe doesn't change the situation. Or do you seriously mean that France doesn't care about such dangerous hazard to people's health?
It's all about censorship plain & simple. There is nothing related to privacy in this fine.
very well done! a plaintext spreadsheet. I think it has a lot of appeal, and for all the reasons outlined. Looking at it raw, is fairly understandable. Awesome! Coolest thing i've seen all month on HN.
They didn't even think to version their API. This is total crap.
regarding the Obama clip, i'm impressed Obama can talk so clearly about how airBnB works, for someone who lives in a bubble of security and probably never thinks about where he's going to stay when he goes on holiday, he can describe very well the social reputation components of airBnB.
It's the media equivalent of adblockers, greasemonkey scripts or custom css: the realization that digital content can be manipulated client-side. Nothing wrong with that.
This looks like a really cool project. I'm excited to see it develop.

How would authentication work with configuration management? I see that new nodes are authenticated with a one-time token generated from the auth server, but that seems like it could be tricky to implement in a dynamic cluster (like an AWS auto scaling group).
The city budget is a yearly flow of cash. You can't directly compare that to equity markets, when equity pricing is at its simplest the discounted future cash flow for eternity.
Fight Patent Trolls: Support the VENUE Act of 2016
Drivers will drive 50,60,90 because playing it faster doesn't make it sound worse, and since it already sounds awful, due to bad acoustics, drivers will want to be off it ASAP
For folks that think I'm being sarcastic, a quick google check returned an average salary for untenured professors at around $45,000 annually. I worked with a guy that banked ~$80k a year delivering pizza to a swanky neighborhood that included a bunch of corporate offices.
Personally I have seen a very significant increase in accuracy. In particular with "real life" scenes, tesseract has a hard time.
That could be. It's especially renovations in the same building where I live that has been the problem here. I'm guessing this is a bigger problem (more renovations!) in a large building, than a small one.
We always unbowdlerize titles. But I don't think "f!@k" is much different from "darn" or (hmm) "dang". People have been doing this to profane words for a long time, probably for as long as profane words have existed.

There's a wonderful Andy Rooney bit about not using such words because he doesn't want to burn in heck.
Cloudera and Hortonworks have raised a ton of VC money, but it is not clear (yet) that they have viable, profitable business models.
Ask HN: Any advice on San Francisco?
I'm headed to SF for the first time ever and was wondering if anyone has any recommendations for places to meet interesting people?
Nice story, but Western Civilization started to fall when the gold standard was left behind for some massive credit scheme that created money from thin air.

Couple that with the rise of China and India along with the rest of the developing world and you have a recipe for no jobs, bad politics, and poor education.

Ross' problem wasn't bad friends, it was entitlement. He always felt that he deserved Rachel when in reality he didn't do anything that impressive or have the self confidence for her to consider otherwise. This was the writers fault, not the actor...
Intelligent Human-Machine Collaboration (2012)
Congratulations, We’re Moving Your Department to Tennessee
it offers some elegance, here's a timeout function blogpost.

http://hyegar.com/2016/03/22/simple-timeouts/

In it the timeout function only takes one arg for its timeout wrapped function, so how do we use functions with more than 1 arg? Via currying
That would be false, sir. https://www.bing.com/webmaster/tools/eu-privacy-request

EDIT: The commenter above me claimed that this was all about hurting Google, and only Google was held to this standard. It looks like he edited his comment when I posted this link, demonstrating he was incorrect. Hopefully this explains my otherwise odd comment.
It doesn't start off as being the same thing. In particular, the new genome might create a very different cell wall than the one from the original bacterium.
Yep, they should have a category for "idiocy" and things like that. Parts with annoying characters, or where they spout off nonsense. Some works are far better when they resist the urge to say dumb things. Example: "We tracked the bad guy down" vs "We tracked the bad guy using the Human Genome Project."
Very good article, it is easy to predict great use cases for JSX concept in the future.

I proposed the idea of using JSX as angular2 templates. They didn't like it and I think the React competition was an important factor for that.

https://github.com/angular/angular/issues/5131
Another feature I've found lacking is that most todo / project management systems are all based around "work hours", and the assumption that you can count on every resource reliably putting in 40 hours per week.

Personal projects look nothing like that. This week I might have 2 hours for it, next week maybe zero hours.
JSX provided a convenient syntax to have named parameters in JavaScript. Additionally, it results in nice data structure literals, and finally, you get the same benefits "for free" in a React app by doing this.

The main thing here was that through thinking about JSX, I was able to reach these conclusions. If I had not had to work with this separate syntax, I may not have tried separating function application from function binding. It's kind of like how when you give something a word you can think about it clearer.

For example, one of the issues thats frustrated me in the past is wanting to fully-curry a function but still have it be callable. For example, if you have id = x => x, if you could curry it it would simply become an "always" function. So like, [...].map(<id x = {5}>) (this maps everything to 5 in our case). But with traditional currying, that would simply return 5. Again, you could achieve this curry(id, {x:5}), but I like the visual queue that JSX syntax gives you saying "This is a new FUNCTION with these parameters".
Ethereum in Practice – Quick Start Guide
It's all very subjective. For example, most of Top Gun is perfectly suitable for a 5 year old...except some of the swearing and the sex. Sure I can find something else to watch with my son (and I do) but I'm not asking for anything more than the version they'd show on NBC.

I'm sure some people may have different uses in mind but that's their business.
All the attempts at 'slack best practices' since this article was written in June 2015 are basically to not do #1, #2, & #3. If Slack is an authoritative source of information that cannot be ignored, you simply aren't doing it right. Slack is a success in my org specifically because it enhances our communication and documentation, not because it has become it.
If you want evolution, you would also have to simulate the cell's environment. Without an environment, there's no natural selection and thus no evolution.
Yeah the "do something" black box includes a cell replication step.

Given genome,

1. Replace genome in host cell

2. Replicate host cell

3. Output "materialized" cell
I don't think that makes it makes his question any less valid. Yosemite has been out 18 months, true, but hypervisor.framework has had a lot of work done - even Docker acknowledges that they've been filing several Radar bugs on it even to this day.

Yes, any new virtualization projects should strongly consider using it, but that doesn't mean any issues with projects with have a massive investment in tooling and ecosystem should be considered deprecated and dead just because of this.
Yeah, I tend to skip the last 20% of post when the first 80% doesn't seem to address the main point of what it's responding to. Like a lot of bleary-eyed people here. Which is why I try to make a habit of getting to the most important part of what I'm responding to first, and deal with secondary or tertiary parts after that. But that's just me.

That said I didn't mean to be condescending, and apologize for it ending up that way.

As to what you were originally saying: I'm not sure your argument will "fly", as it were -- for the simple reason what most strongly predicts the carbon impact of a means of transport is not transit time but, generally, the amount of energy expended to get from A to B (not the transit time). And even though the flight may be shorter, something tells me the energy expenditure has to be much higher for supersonic than for subsonic flight -- in part precisely it needs to get to a much higher speed (i.e. get there with "decreased flight time") and attain a higher altitude before coming down again.
When properly supported mass transit is much cheaper than individual cars. BART is under $5/passenger trip. http://www.vitalsigns.mtc.ca.gov/transit-system-efficiency
This.

Any modern standrards-compliant implementation of JS (following ES5 and especially ES6/ES2015 standard) already has everything that a sane programmer would ever need.
Ticket to Ride, Carcassonne, NS Hex... are board games.

You can also play Chess on your phone, it's not what most people mean by fun video games.

At least Tiny Wings is a video game. But, compared to say a side scrolling BMX game on Gameboy it's clearly lacking.
It's more like how the money is being spent. The political landscape is totally binary so the only question allowed is whether something gets done or not. Once the decision has been made it gets done in the least efficient way and no further questions are asked. Or it gets stopped.

Just look at Obamacare: There is no public discussion about the details that could use improvement. Either it's all in or people want to totally cancel it. Nothing in between.
Is it related to the work started by Brad Fitzpatrick a few months ago with the goal of implementing client-server gateway between the host and the guest filesystem using FUSE?
Well, they had to have a receptive cell to bootstrap this thing, that is true.

Yet, since we're talking about mycoplasma here, they don't have a cell wall (only plasma membrane) nor mitochondria (only eukaryotes have those). The new minimal genome really has to synthesize everything needed by the cell to grow and divide.
France can get lost. They may get to censor France; they don't get to censor the planet.

And if France does, does China? ISIS? Trump? Me, too?
I know that France hasn't literally banned humans with allergies, but allowing animals that spread dander everywhere makes the environment hazardous to anyone with serious pet allergies.

Also, if you're going to continue with the ad hominem attacks, could you at least explain how 'blaming other people for your problems' is even applicable? It isn't obvious to me at all.
Haha, which streets? I'm a bike messenger here in SF and haven't noticed any streets that are noticeably bike-paced. I have noticed car-paced series of lights like fell/oak/masonic in the haight where you have to book it at 30-40mph to make it through efficiently.

Edit: now that i'm thinking about it, a lot of the streets in the TL, fidi, and soma are pretty well timed for bikes, but for a faster pace, like 20 or so, and maybe 25-30 for the big soma streets like folsom, howard, harrison, bryant.
It's interesting all the solutions people come up with to tackle GTD. I don't think i've met two people with the same implementation. But really, whats important is finding something that works for you, and thats different for everyone.

Relatedly, I built something for myself, but am working on launching it. I wasn't satisfied with any GTD options out there, and really just wanted a brain for my brain. Something i could just dump thoughts and todos into and it would automatically manage them for me.

You can actually see some of this in action in the screenshot from a recent update: http://blog.mindaux.com/blog/2016/02/27/sneak-peak-beta-acce...
It sort of depends on how long you intend to live in a house. For mortgages that are on 5yr terms, look at longer term averages.

For example, New Zealand (another market I'm familiar with) is currently running at 4%/yr for a 2yr mortgage and 5.5% for a 5yr. However, for budgeting purposes, most people will budget at 8%/yr, since that's the long-term average.

Just to completely freak you out, during the GFC, I hit 12% annual interest. My parents hit 20% during the Canadian inflation crisis of '81. :)

Go for the high end, don't be afraid of a smaller house, build up the equity and then move. However, be aware that closing costs are significant, so it's best to amortize them over several years - that's why housing calculators ask how long you will live in a house.

Frankly? If you're afraid of 5%, you probably don't want to own a house, or at least, you don't want to own _that_ house.
This is not some body arbitrarily requesting removal of information. This is a body judging the legitimacy of requests on the behalf of a private individual. That is not censorship and I believe it's an attack on a fundamental human right to say that Google has the power to do whatever they wish with your private information that is outside of the public interest. Google is not a journalist or a news source.
What would you do to remove some unpleasant information about yourself from <some other publishing method>?
But... at every cell division, two half cells will be built. So after twenty divisions, there will (on average) be a millionth part of the original cell in every descendant.

I don't really see the point in creating all organelles outside a cell. When we copy the functionality chemically, the results are very different. (Air planes not flapping their wings, etc.)
Without knowing much of how npm works, I'm going to assume you have ways of protecting yourself there too. If nothing else, good old "cp -r" can effectively let you pin to a version.

The point is that people use package managers and third party modules installed from them to automate tedious work, and anything automated will have the potential to do something other than what you want. Is that risk high? Not really, but it's not zero either.
I really liked the Chaos Rings games, and the Final Fantasy remakes. Square Enix did a bang-up job. I'm on android now, but years ago I also loved the concept for Sword and Poker. Thats at least 5 games there. All (save for Sword and Poker) had a production value on par with most games for the Gameboy.
Import Python modules from Twitter
> We need to value density as it allows for more compact living.

rack em and stack em, eh?

recent research finds that people living in low-density suburbs are happier than people living in cities. People living in rural areas are happiest of all.

http://ti.org/antiplanner/?p=11673

We can promote more "compact living" but the data shows it degrades human happiness.
For this problem, Getting Things Done says you should only record the next task. The second doesn't interest you as you only need to think about it once you're done with the first.

Work projects have multiple dependencies because they involve often many people, but Agile has been also pushing backward the desire to plan too much in advance.
If you cannot afford whatever method is available to get home when hammered, the solution is not drunk driving, the solution is NOT DRINKING.

You guys are framing this debate as if going out and getting drunk in a bar is a necessity for life, it isn't.
blogspam, https://news.ycombinator.com/item?id=11352389
for example Festo
This is a minor plot point in "The Big Over Easy" by Jasper Fforde [0], which features a road that plays Jerusalem if you drive along the rumble strips at precisely twenty-nine miles per hour. Personally, I prefer the Stockhausen symphonies of the potholes on the M25.

[0] http://www.amazon.com/Big-Over-Easy-Nursery-Crime/dp/0143037...
We do. Especially at night.

Normally those red lights are placed around schools and such.

If you're a responsible driver, you're already driving at the speed limit at those sites.