skysight-inc/HackerNews huggingface dataset:
Honestly kegg is more useful because it's interactive and hyperlinked and contains species specific information (identified genes in genomes)

http://www.genome.jp/kegg-bin/show_pathway?hsa01100
And since what I really want for systems programming is a library like http://research.microsoft.com/en-us/um/people/nick/coqasm.pd..., at some level it's inevitable I wouldn't find Rust powerful enough.
For a few decades I have had a balanced view of supporting libre, open source, and proprietary software.

Now for political reasons (my anti-globalization and anti-one world government / TPP / TPIP feelings), I am favoring libre software as one more small technique for supporting local business and generally smaller companies and organizations.
From my perspective, SPG was the best rewards card of 2007. It's the best overall rewards offered by American Express, but there are better cards. It, of course, depends on your spending habits but off the top of my head, I'd opt for Citi Prestige or Chase Sapphire over SPG.

Besides, people who want to maximize rewards will specialize. BCP for 6% back on groceries, Sallie Mae for 5% on Amazon and Gas (discontinued), Prestige for 5% back on travel, Ink for 5% back on utilities, Discover and Freedom for their rotating 5% categories and great online cashback, and finally something like Citi DoubleCash for 2% on everything else. A single general-purpose card can't compete with a stable of specialists. And if somebody lacks the spending to support ROI on several cards including some with annual fees, that person is not the lucrative VIP you're after.
From https://en.wikipedia.org/wiki/Cromwell%27s_rule

> If the prior probability assigned to a hypothesis is 0 or 1, then, by Bayes' theorem, the posterior probability (probability of the hypothesis, given the evidence) is forced to be 0 or 1 as well; no evidence, no matter how strong, could have any influence.
For a lot of things, that extra resolution is not really any benefit. Particularly for content that wasn't ever recorded at that level of fidelity anyway - I don't need 4k versions of Seinfeld re-runs, or SpongeBob SquarePants for the kiddos. Most of that stuff doesn't even need to be 720p.

Besides, pirated video content was really the only thing that most normal people could fill up their hard drives with (okay, maybe GoPro people or people with huge Steam libraries, too), but the Netflix and YouTube and Amazon Prime have taken a huge chunk out of that.
next up:

ID required to use one of the few remaining public pay phones.

good thing VoIP service and public wifi hotspots aren't widespread, otherwise the proposed legislation would be pointless. Oh, wait...
Good news. ReactOS is really moving as alternative to Windows.
A new edition of Burke's writings, speeches, and essays
If it just gets encoded at the same semantic level as text or an AST, then what do you really gain by using modules? That doesn't seem like as big of a win as people asking for modules seem to think it is.
In that case you could just use a binary tree taking from lsb to msb, and then expand down a level only on collisions.

The reason for primes is that it is more likely to distinguish between numbers earlier in the tree so that it doesn't get as deep as fast. Where a binary tree couldn't tell 0 and 256 apart until the 8th level, this could tell them apart at the second level: 0 mod 3 = 0, 256 mod 3 = 1
If you missed that sallie mae card, you can get amazon's house card for a flat 5% statement credit directly applied each statement. It's zero hassle. There's no reason to choose the 3% amazon chase card.

Also, I simply can't figure out how amex makes money on the bcp. I hit the full $6k of groceries and just use it for groceries and gas.
GC is intractable with pointer arithmetic.

Edit: to be clear, this is the classic difference between a reference (a value without arithmetic) vs a pointer.
If you're using your computer while you have a concussion try switching to 'white-on-black'. No guarantees but it definitely helped me when I was in that situation.
I'm not sure his idea about "merging memory and storage" really makes sense. He says that he wants load instructions to be able to hit the disk in order to avoid "calls to input/output routines in the operating system." But you can't avoid the input/output routines --- he's effectively saying that we should hardcode our filesystems into a single machine instruction and let the processor figure it out. If anything, we're moving farther from this model, since VMs give us virtual address spaces inside virtual address spaces.

I don't think this is just a security issue; it really breaks all of the assumptions that we like to make in modern programming languages.
In what format does a rendered image come out? How large is it? How is editing done?
Mate, you should consider checking and improving your English grammar. With this level of mistakes, many people won't bother checking your product or service at all. Most probably English isn't what you are good at; however, if you have ambitions of building something of worldwide importance, it is imperative to have a good command of English.
Except you let the machine handle that for you with RAID.
Oh bummer, yeah analysis-type tasks is precisely where the REPL is most essential, not going to lie. I hope https://github.com/rust-lang/rfcs/blob/master/text/1298-incr... will help bridge the gap. And perhaps help with writing a REPL too...
Some people do millions in manufactured spending a month.

(Source: http://www.travelcodex.com/2016/02/how-much-manufactured-spe...)
I find it interesting that they've chosen to partner with different vendors (and different card networks) in other jurisdictions - here in Canada, the new Costco card is a MasterCard in partnership with Capital One.
Original article here: https://theconversation.com/a-golden-age-of-ancient-dna-scie... with more than a few comments raising questions about the actual meaning of the x% figures given in this article.
That's really terrible design. It seems almost unfair to charge these guys for exploiting such an obvious loophole.
Well, you could always wear one of these...And use standard Java, or even Scala: https://goo.gl/2t5hBX
Right. It's no accident (badum-psh!) that Russia and China are full of expensive cars with dashcams. Or even just regular cars with dashcams. The benefits far outweigh the penalties for the vast majority of dashcam users.
You have to separate work (and studying) from hobbies.

It's great if your work is what you enjoy doing, but that won't always be the case. So focus your studying on what appear to be long-term saleable skills that will lead to a job (or to an academic life, if that is your objective).
> why you have been driving like a jackass

Or just don't drive like a jackass. It's a serious business, take it seriously.
I'm very glad someone brought this up. The whole talk is kind of weird. David is extremely nervous, drinking all the time, and then (spontaneously) bursts into tears in the end. One comment read that he was 'high', and, while there's no way (or point) to verify this, it describes his abnormal nervousness pretty well.

Adding to this the fact that this achievement hasn't been verified, leads to a very strange TED Talk.

So, I started wondering, whether a deliberately bad TED talk can be considered a good magic trick...?
I was asked for an ID buying a pre-paid SIM card in Germany 3 years ago or so.

Seems that the regulations are even more strict now and you need to register it to an address.

https://www.tripadvisor.co.uk/ShowTopic-g187275-i116-k914854...
Killed by gravity versus killed by the other players, makes it much less a human story.
My wife and I flew business class from SFO to Greece last year, airfare that would've cost $25k to book cost us $2k cash and the reward points from about 18 months worth of spending. In this case, it was on British Airways co-brand card that gave us 100k mile bonuses (to each of us). One $11.5k business class ticket ran about 190k miles, and we earned a companion pass for spending $30k on the card in a year. (The flight was great, and combined with the BA lounges saved us from the schlep).

Most of our spending is on cards that earn cash (or cash-redeemable) rewards but I love to take advantage of big bonuses on co-branded cards. We also earned 250k AA miles, 100k from a bonus on a new card, and the rest from US Airways cards that Barclays was giving away to burn thru their cache of prepaid miles ahead of the AA merger. I cancel the card the following year before the annual fee hits -- or not, because often it's waived for a second year. Don't get crazy and it doesn't impact your credit.
I don't think there's a data race there, but the compiler can't check that. What the compiler sees is more than one thread accessing the variable `data`, which could cause a data race.
Hmm, the lifetime expectancy for football players is surely lower than those others? Football doesn't need to kill you outright to harm you the most.
Flappy bird game implemented in Super Mario World
If I understand correctly, Backpack's design is primarily driven by compatibility considerations (“how do we build upon GHC's existing foundation?”), rather than elegance. In particular, Backpack doesn't eliminate those ugly .hs-boot files, it just automates and hides their generation and processing.

For all their faults, Standard ML and OCaml have pretty good support for modular programming. And, as the Modular Type Classes paper you linked shows, type classes can be built elegantly on top of a good modular foundation.
im obviously missing something here, hopefully someone can explain?

I understand the eventloop/nexttick/etc architecture of node, but i dont understand how in this case he was blocking the loop? Shouldnt all the operations to S3 be async (and thus non-blocking, even if waiting for a timeout)? What was the specific part in this scenario that was causing the loop to stall?
Side question: Is it customary to drive across the dotted lane?
Yeah, fuck people who are medically unfortunate. Or does PITA mean something other than I think here?

Either way, there is a legitimate condition for which this could be a useful thing, I don't see why you should be disrespectful to people with a condition. However, if you're referring to the gluten-free pretenders, I won't argue.
This is one of those pieces where you read it, initially nod along and think it just seems like common sense, and then realise with a little sadness that your own businesses could probably be doing better if you spent more development effort on actually doing those common sense things. Well worth a read for would-be unicorns and smaller businesses alike, IMHO.
The 5% statement credit on the Amazon card is only for Prime members, so if you're not already one that could be a big reason to stick with the 3%.
nodesocket? Let me see your real Internet ID.
This article has a bit of a 'just-so' vibe to me. What about a company like Uber? Uber doesn't have any virtuous loops, mounting loss, or cumulative benefits of use.

Now, I don't mean to argue against a straw man, I know that this article isn't claiming that only businesses with these features can be worth >1b - but exactly what is the ratio of companies north of 1b that have these properties? That is what really decides the predictive and analytic value of this model, not some cherry-picked stories that happen to adhere to it.

And also don't get me wrong, these things make intuitive sense to me as well. But i'd just like to see a more careful, rigorous analysis of these commonly accepted articles of faith in the startup world.
I attended a really good guest lecture by Dr.David Reich (with additional work also by Dr.Nick Patterson) on analyzing ancient DNA.

"Massive migration from the [Anatolian] steppe is a source for Indo-European languages in Europe"

I can't find the slides/video recording anywhere (it's a shame because it was the most accessible presentation on genetics I found to everyone).

Dr.Reich didn't go into too much technical details during the lecture; the audience was to a bunch of undergrad and first year grad students interested in computational biology; and guest lecturers are PIs around the Boston area who are trying to recruit for students into their labs.

However, he did hint some of analysis they did to construct the migration path came from the distribution of particular classes of metabolic genes for different diets; meaning, early human beings can be classified as farmers (grain-based diet), hunter-gatherers (raw meat) and nomadic people (consume more animal products, lactose); by collecting samples collected in Europe, carbon-dating them and constructing phylogeny tree (most percentage of shared single nucleotide polymorphism are classified as siblings, least likely amount of base mutations to the target offsprings are labeled as parents) amongst the samples and classifying them amongst these three diet-based cohorts and sample-collection sites, you can begin to construct a likely migratory path.

Also Dr.Riech also made an interesting point that the reason why most ancient DNA research is done in Europe and not really in Africa which would seem more logical is because: most grants to do the work come from European scientific agencies who have mandates to fund their own anthropology and culture studies (an unintended "Eurocentric" side-affect of research grants).

Here is the Nature article instead:
http://www.nature.com/nature/journal/v522/n7555/abs/nature14...

Non-paywall version: http://arxiv.org/pdf/1502.02783.pdf
Only if you have prime.
I don't know, but I do know that in my pocket my wallet is a simple iphone sleeve and I keep my ID, transit card, and only 2 credit cards -- and BCP is one of them. The giant credit line and secondary benefits like roadside assistance just gives me a peace of mind in American Express. A friend once needed an air ambulance in central america and the pilot wouldn't fly without guarantee of payment -- Amex approved a $30k authorization over the phone with the pilot on his PRG. Also, they've always been on my side in disputes. I had an issue with Stamps.com, i was busy, i waited months to resolve it, i didn't ask for it all to be refunded but it just was.

I imagine that brand loyalty will be worth it for Amex in the long run, but i'm certainly coming out ahead for now.
FWIIW; worked in Kryder's lab at Hammerschlag Hall as an undergraduate in the 90s: he's one of the best people I've met in the sciences. The E.O. Lawrence of hard drive technology.
That's by far not the worst thing, the 7/7 bombings had more intelligence, as US, French and Israeli sources gave many details including names and sigint intercepts one of the "suspects" was arrested and then released 24 hours before the attack happened he later slipped the police surveillance (which according to some reports was not even plain cloths but literally a police van trailing him) and rejoined his friends (who's names and details were also known) and went on with the bombings.

Many European countries already have regulations around pre-paid sims and burner phones it just doesn't matter (especially when the terrorists are European nationals).

The biggest problem is that overall in Europe security forces do not have the budget nor manpower to deal with neither foreign nor homegrown terrorist threats and in the current political climate the fear the media more than the actual terrorists.
If it's not done automatically it won't routinely happen though. I wonder about this with some sensors at home. Some of them routinely ping me with status but other commercial ones are pretty much fire and forget. I can certainly set calendar entries to run tests but you're better off with things are self-testing in some manner.
Seth Bling implements a small game on a real console version of Super Mario World by moving the character in certain patterns. Explanation starts at 0:26:20 and flappy bird game play at 1:26:00
The original author does say in the introduction that this is a framework for evaluating "non-transactional consumer companies". Presumably in this context Uber is transactional.
The basic premise:

“We the government, who represent the people, are in the business of exploiting the people’s unfamiliarity with probability. You the retailer, who represent us, are not supposed to be in the business of exploiting our unfamiliarity with security.”
Well. Check if the auth DNS of said failed domains are served by Cloudflare DNS. And then we go from there.
They will ask you if your door was locked. Sure, you could lie, but that's also insurance fraud.

I also never leave my house unlocked, even when I'm inside.
According to her bio, she works in Stripe's machine learning department so clearly a smart gal and appears to have a great amount of humility - enjoyed her post, was easy to digest and a light read.
ZeroTier are awesome and an inspiration for us.

They built their own technology, as opposed to us (we use SoftEther[1]) and it is very clever how they only use the servers as a sort of "meeting point" when possible.

I think however that both companies focus on different markets. We focus on small teams and MSP-like companies, because other targets don't seem ripe enough for our marketing power (i.e. money available to get into some markets).

I'm not fully sure about their focus though. At some point I thought they were after the enterprise, now I'm not so sure.

There are so many applications for our products that it's difficult to choose one, too (Docker multi-host networking, per-application networks, ...)

[1]: https://softether.org
I also was a bit surprised to realize all the comments here were completely missing the point of the actual article and only a response to the headline.

Coincidentally this very active discussion on another article is taking place and likely a good resource for anyone seeking a more relevant conversation with regards to depression:

https://news.ycombinator.com/item?id=11367325
It depends on what you value. I use my BA Chase card exclusively, because with ~$100,000 worth of spending you can get a pair of RT BA First trans-Atlantic tickets for about the price of coach.

Are those "worth" the $10,000-$20,000 fare difference? Surely not, but to me they're worth more than the ~$2,000 I'd get from the best cash back cards.

These partner cards really are marketing genius, and a great way to capture more attention, dollars & loyalty from your best customers.
If VR gets popular, it might be a driver for higher storage demands. For non-foveated imagery 4K is even quite limited.
That seems to go against their "no jerks" policy they're so proud of
I don't have any personal experience with MBNA, but I assume it means the agreement you sign forces you to use binding arbitration in place of suing MBNA. And being always right just means that basically MBNA will always in in arbitration. So you are stuck in a contract with a company you can't sue or win against if they break the contract.
I had this problem when I was an undergraduate.

I think that if you have the energy and intellectual capacity to follow these various interests without it adversely affecting your grades or future prospects (I didn't) then it's not problematic.

Otherwise you need to develop stronger self-discipline in order to get done what's necessary to jump through the hoops the system requires you to jump through. I wasn't able to develop this until several years later in life but I think that if I had been able to do so while still in university my life may have turned out better (though one can never really know).

As for how to develop this discipline, I don't really know because for me it just seemed to happen when the time was right. Meditation may help because it can help you gain some distance from your thoughts and feelings and make decisions about what to do from a calmer, higher level perspective, rather than following your immediate curiosity.

In any case I don't think you should try to suppress your interests too strongly. At this stage of your life you should be exploring different interests so that you can develop a clearer idea of what you really want to focus on. The key is maintaining balance and making sure that you're spending enough time and energy on your current course of study.
Do you think like a YC Partner?
So you intentionally mount these things front/rear and plainly visible to police? Interesting. Also, what model camera did you buy?
Yes that's an important point. There are diminishing returns with better resolutions. Twice the resolution doesn't mean it appears twice as good, and at higher resolutions it can even be hard to tell. At some point you exceed the resolution of the human eye and ear.

But I think storage space still matters on mobile. I haven't come close to filling up my laptop after 4 years of use, but I have to be careful about putting stuff on my iPod. Still it can store dozens of hours of audio, so it's not the biggest issue.
Also, an awful lot of people who sound like infallible "experts" in tech are just people who are dealing poorly with imposter syndrome.
Or make the perks special services, rather than monetary rewards. For instance, I've heard of many high-end cards that provide general-purpose concierge services with membership.
> simpler ppx transformer

The simple example does not look 'simple' though.

> https://blogs.janestreet.com/extension-points-or-how-ocaml-i...

user calls it a 'bloody hack' and 'we are still far away from Lisp here.'
At $95 I think I'll pass.
Not really - they are just focusing on different aspects of the story.

What I find most amazing is the author can present scientific evidence that Neanderthals were different species and the consequence of what this means is completely ignored.
It's survivorship bias. Sure, it's easy to point out how obvious the winners were, but there are probably 10 others that looked like winners but ended up failing.
oops, you're totally right, but if you have the level of amazon spending that justifies prime, this basically makes prime free at the price of remembering to pay that card off one a month...
I agree that backpack leaves Haskell with too many overlapping concepts. But consider things could be unified internally, and compatibility-breaking language extensions introduced down the road. That's my hope at least :).

Also, check out https://www.mpi-sws.org/~rossberg/1ml/ . I think it makes a pretty good argument that there is a similar problem going on with the MLs versus the ideal too. (The overlapping features are also not a subset of Haskell's overlapping features, interestingly too.)
Milestones from the Last 15 Years of Web API History
The 2.9% + 30cents on every transaction

There's the flaw in this idea.

The merchant's bank collects 2.9% + 30 cents (in this example). A portion of this is transferred to the issuing bank.

The amount transferred is called the Interchange Fee, and it is significantly lower than that amount. There are different fees depending on the card type, credit/debit, rewards, business cards, etc.. and they are set by Visa/MasterCard/etc. Discover and Amex have more latitude here, since they are both the issuing and acquiring bank... but if they raise fees too high, merchants will just stop accepting their cards.

Interest from the card balance is kept by the issuing bank.

So you see, revenue from credit cards is divided between multiple parties...
https://www.youtube.com/watch?v=PUf1d-GuK0Q