skysight-inc/HackerNews huggingface dataset:
> Church says that genome-editing techniques will remain the go-to choice for most applications ...

George Church is kind of a sarcastic name for a genetic scientist..

But the ethics question is more open then ever.
Didn't you immediately think about how cool it would be if we could program these organisms to do stuff ? I did.
Could you then program it to become multi-cellular ?

How long before this can be achieved ? 10 years ? 50 ?

However, "Because it’s there" is a worrying motivation to pursue this knowledge, because the pandora's box it opens is very real.

We're getting closer to the point were we can play God and achieve magical technological feats.

But are we mature enough to handle the powers that this technology bestows upon us ?
Do we really need this technology now ?
that's a nice write up and very helpful.
Yup. I would much rather take a 4-6 hour train to a city here in the Northeast US, even if the flight is a quick one-hour jaunt - which comes with an hour-long ride to the airport, anywhere from 30 minutes to an hour (or more) dealing with security, and crappy expensive internet in-flight while my knees are jammed up against my chin. (Unless the person in front of me decides to recline their seat, in which case I have to store them in my cheeks like a chipmunk.)
Yes! And while we're on the subject, how about the unfair dominance of Internet Explorer?
It's good to see that you folks are taking ownership of such a critical portion of this infrastructure. I hope you understand why people can get worried when Docker has a history of integrating with third party software, and responding "Not Our Problem" when problems arise.
Welcome to Hillstone, America's Favorite Restaurant
>I guess I got confused by your mentioning of "a PGP public key" because it is a very odd way to put it, and seems orthogonal to the discussion here that Tor hidden services are useful to people other than for black-market eCommerce operations.

This is what I was responding to

>The use of hidden services for large sites is that they authenticate the site without the person uploading the documents having to trust the CA system. And the person doing the uploading has to use Tor or something like it because otherwise their adversary would just block them from accessing that site or punish them for it, and Tor is better than something like a VPN in that regard because the uploader only has to trust the design of Tor, not an individual operator like a VPN.

It sounds like AnthonyMouse was suggesting that .onions would be a good way of sharing documents with "large sites" in scenarios where it is important for the user (note: not the site) to hide from someone they aren't the biggest friends with.

Problem with this suggestion is that .onions don't really offer any benefits to an user wanting to hide their activities, but in fact hurt them by dramatically slowing down any transfers (This could be a serious issue for time sensitive stuff).

Therefore, instead of offering an .onion version of their site any such organizations and their users would be better served by a web service on the clearnet with an associated PGP public key that the users could use to encrypt any uploads.
I'm just telling it how it is. If you wanna sit there in Chicago and tell me there's no crime and no class conflict going on in the Mission District of San Francisco, well, that's on you.
I went to the article to try and dig up information about the orthologues, but as is kind of par for the course these days, the meat of the useful information is not readily available.

If you go to the supplementary information, you can find an excel sheet with the locus and amino acid sequences for all the genes. It's then just a matter of blasting the unknown function genes against the human genome and using a cutoff for similarity. I'm going to have to wait to do this next week, but if any enterprising soul wants to do this, you can get the supplementary data here:

http://science.sciencemag.org/content/351/6280/aad6253/suppl...
Maybe fewer people would be complaining about opt-in filtering if the thread were titled "Watch movies with the freedom NOT to filter". This protocol would actually help those that want to watch their TV unfiltered because because it could replace the current system of filtering being forced on everybody.
Power assisted bicycles that take minimum effort to go 20mph would be amazing
>And as an individual I should have the right to remove that information.

Information that you published, sure, but the "right to be forgotten" is about what other people published about you, and your inconvenience does not trump those other people's rights.

When a news story about you is inconvenient and damaging to your reputation is when it matters most that it stay online and reachable.
unbound is great for this.
> 1) How does session archiving work with non-line-oriented applications? (e.g. top and its brethren)

We capture and replay the whole stream, so playback works well with top/mc/emacs/vim etc

> 2) Does it ever capture passwords (or any other non-echoed characters) by accident?

If you accidentally type in password in your active session that will be visible, session capture will record it, yes. We plan on encrypting everything just in case at rest though:

https://github.com/gravitational/teleport/issues/262

> 3) Does it require a TTY?

You'd need PTY for interactive sessions, however `exec` will work through ssh just as well (as long as teleport talks vanilla SSH)

> 4) Can it multiplex sessions across multiple servers?

Yes, we just did not expose it in the UI yet
Sorts and Filters Suck
The 'whale' terminology is taken from casinos not from fishing.
I have a strong suspicion that is exactly what would happen.
HN is explicitly not just about startups and tech:

https://news.ycombinator.com/newsguidelines.html
I guess we'll have to agree to disagree. However, I know film is art, but movies are mostly watched for entertainment. Censoring entertainment seems totally fine to me -- I should be able to skip watching part of a baseball game if I want. Hell, it's MY mind and eyes -- why don't I get to control what goes in? Maybe I like 95% of something. Is that to be withheld because I don't like the other 5%?
Planetary protection
There are a lot of things that are good ideas, but that cannot be implemented without side effects that far outweigh any conceivable benefits to society.

The "right to be forgotten" is one of them.
Usually I recommend Avangate, Bluesnap, Cleverbrige or Fastspring. The best part is that with these services there is nothing to configure. You just link to your page on their servers, they even theme it for you.

Downside: The cost is somewhat higher. So I don't think they work for a low margin business.
A half century ago, the federal and state civil services weren't, I think, unionised, which means that politicians couldn't be bought by unions to give civil servants more benefits to increase union dues to buy more benefits to increase dues to buy more benefits.
Stripe has a much, much better API. I've used both, and the code I've had to write to integrate with Braintree is about 3x as much as the code I've had to write for Stripe.
Get ready for Swift 3.0 -Remove of ++ – and C style for loops across a project
Agree with that. I wanted this feature for a while but after thinking about it, I think that it would be bad. It would change the focus on the first, second, and slightly third comment where all the other comments in the trees will be disregarded. But right now each comment is valued and has its place. There are less focus on the last leaves but it's still great.

If it's done, the first comments will have all the attention plus it will engage to a race to have the best first comment. We want to seek to engage people with real thoughts and deep discussions, regardless their position here. I have read so many long and great conversations between highly skilled persons, it's so valuable. We have to keep it like that.
Thanks for the comments. Actually, I was just working on importing Excel spreadsheets into Stencila sheets last night. Some interesting aspects involved in translating Excel formulas into R expressions e.g. `AVERAGE(A1:A5)` to `mean(A1:A5)`. To do it properly looks like we'll need to build an Excel formula parser. But do-able - and could be fun!
What is the process by which "samples" are drawn from the population of intelligent beings? This is a keystone of the article's argument, but it entirely hand-waved. It is not as if "intelligences" are created in the void and then assigned with some random distribution (uniform or otherwise) to bodies on planets-- each intelligent being in the universe is itself with probability 1.
I don't think it necessarily follows that a minimal genome has the minimal cell or vice versa. It really depends on how much support structure (the rich media) is provided and the specific details of how the genome produces the cell structure, and the cell structure details.

One can imagine little cycles of genes that all need each other, but don't actually provide any extra fitness. IIRC the Venter method can't identify and remove those sorts of cyclic dependencies if the cycle is more than 1-2 long.
You can just use it and pay a fee every time, or you can subscribe and get Free Delivery... of course they still charge more than most of the stores for the groceries themselves. I subscribed last year for both myself and so I could send my mom groceries, and barely, barely broke even: 25 orders. Given the price increases since then, you'd still need 25 orders to break even.
Buddhist Econ: Prioritizing People Over Products and Creativity Over Consumption
Don't equate spending with good governance.

New York figured out the tax collection thing, and our schools and other infrastructure cost more and work poorly.

Also, the Feds fund a wide variety of state operations, especially in social services and transport.
Ew. This sounds very tasteless.

How about doing something creative and that's not navel gazing or better yet use this money on OS X.
I have yet to meet anyone who kept and followed a todo list over the long term. Can anyone say otherwise?

It just doesn't seem to be human nature to do it consistently beyond short bursts of focus, like dieting and following step-by-step procedures.
You're saying the inverse of the OP's solution. He'd skip over 5%. You're arguing it's not OK to skip over 95%. Skipping 5% of a political speech would probably not be bad, especially if you knew before hand what you specifically didn't want to hear (because you knew what was going to be said). Maybe I've made up my mind on the war on Iraq and I just do not want to hear any more about it. If I don't care about a candidate's position on whether it was right or wrong, don't I have a right to skip that part of their speech?
It might make sense to add a (textual) description of the severity levels to the format. Then, the viewer can check that description to decide what level they are comfortable with.

The obvious drawback of that approach (shared with tags) is that the description needs to be in some language. This clearly hurts internationalization efforts.
The implementation really is the problem here. There just isn't a way that this can be implemented fairly. Or maybe there is, but trying to force it before we've found the right way to implement it just isn't working. Obviously it would be great if the Internet really could forget about the stupid things I've done. It would be even better (for me) if I could get everyone to literally forget about those things. Of course there's not an ethical way for me to get other people to literally forget things, and I think what GP is saying (and I agree) is that there's also not an ethical way to get the Internet to forget things.
I'll grant that it may be good by US standards, but that is sort of damning it with faint praise. Yes, it is good in the sense that you can get anywhere you want to go, eventually. When I say good, however, I mean comparable to driving in time and convenience.
I thought it was weird because I had never seen it as a kid. But tons of people (roommates, etc.) did it in college, so no, it's not considered weird.
> So what's to prevent China from enacting a law that protects the privacy of its leaders and then demanding Google to remove all traces of any mention of any of its leaders, past or present, from the entire Internet?

Nothing, because China is sovereign state. On the other hand, the European right to be forgotten does not require Google to comply with China's government demands. What China may demand of Google has nothing to do with the current topic.
Doesn't that make the original statement a tautology? If the market doesn't care about the 99% that play but don't pay, of course video games are nothing but a costly addiction.
Ask HN: How far away are self-programming computers?
Say a system scans all publicly available source code and, given it's knowledge of the compiler / interpreter, is able to determine the function each block of code.

Could this system learn how to build software given human language instructions as input.

How far in to the future might this sort of system be?
Nah, congresspeople do this all the time for people affected who are in their constituency. It's just not federally done.

I see things like this periodically: http://www.smdailyjournal.com/articles/lnews/2016-03-19/esca...
and I wouldn't call that extraordinary.
Fair enough, that's an example that wouldn't worry me one bit.

You're right it's other people's business, I'm not saying this kind of tool should be banned! I'm just voicing a concern that it might be unhealthy for people to set up automatic filters for stuff they find offensive, across all their film and TV. I think people should be offended sometimes. Not that anyone should try to offend people for the sake of it, but I think occasionally seeing stuff that challenges your sensibilities (in the context of good literature, ideally) probably helps people to be more tolerant and less reactionary.
Ask HN: Is anyone else excited for a bubble burst?
It seems like such an odd thing for me to look forward to. I keep thinking that there are so many companies which...just shouldn't be funded at all. Part of me is excited for a lot of the dead wood to be burned off, and part of me wants to see how well I can weather the storm. Does anyone else think this way or am I just the oddball here?
The Elusive ‘Runner’s High’ Has Prehistoric Roots
Well the company might have been upset that you willingly used that picture as the most accurate description of yourself. If it was a picture that someone else posted of you, they might have been less upset.

Also, even without right to be forgotten, you could legally compel people to take down the picture, and google to delist the picture via DMCA request assuming you or someone you are friends with took the picture.
I've seen Project Managers who are all about GTD and follow it consistently. Not my cup of tea, but it works for some I guess.
>People never see a property price crash coming.

People always see the property price crash coming. People know, intuitively, housing can't go up 20% or 50% or whatever every year. It's just that they think they can make money and get out before the crash happens. Let me put on my Carnac the Magnificent turban and tell you there's definitely a property price crash coming in Toronto and Vancouver. Guaranteed.

The problem is you have to know when it's coming to cash in, and I can't help you there. If I could I'd be buying up million dollar houses. These things last way, way longer than I expect.
This is a real bummer because it implies they are done developing it.

I bought the Nik Collection a couple years ago and I have gotten good value out of the product. I hoped they would continue to improve it.

If you like photography should should definitely download it.
Services like Mint, Personal Capital, MoneyWiz, etc don't directly store or use your banking login, they pay to go through secure, well-known services like Yodlee http://www.yodlee.com

Is privacy.com actually asking for bank logins, or just your bank account number/routing? In either case, it is nothing new or uniquely scary about this service. If you're not comfortable with this, then there really aren't any third-party online banking apps you are going to be comfortable with anyway.
"Go ahead and try to design a game that focuses on "whales", see how the works out."

This basically describes Las Vegas.
One angry programmer almost broke the Internet by deleting eleven lines of code
The big problem of the freemium model is, that it seems to push developers to make bad games. The model is based on making people repeatedly spend money on the game - and that is too often done by blocking the game until more money is spent, which of course creates a bad gaming experience. With a fully paid game, the incentive is to entertain the user to a point that he is happy with the purchase and spreads the word.

Around the time the mobile world got dominated by freemium games, I bought myself a Nintendo 3DS and I have not regretted it. The games are much more expensive up front, but they do offer very elaborate gameplay and long time fun.
Fair point; the Gawker analogy doesn’t work here.
> it's like separating Gmail, search and ads from Google. all you gonna do is kill it.

No, Gmail would almost certainly survive if split off from Google. Search and ads are basically the same product, so splitting those would weaken both but not kill either. Google search has some of the strongest engineers at Google and a near monopoly on the market, their engineers could easily build an ad system for search from scratch. Ads would be weakened but not killed - they also have some of the strongest engineers at Google; they still serve ads on mobile and AdWords.
In case anyone is curious, I have since posted some additional thoughts:

1. Unifying default parameters with curried named parameters: https://tonicdev.com/tolmasky/default-parameters-with-generi...

2. Using generic JSX to declaratively specify JavaScript ASTs: https://tonicdev.com/tolmasky/generic-jsx-for-babel-javascri...
"shitty and old" is now "vintage" to the right crowd. someone who owns a crooked bike shop is probably stripping and repainting old cheap frames and marketing them to young hipsters.
> there's also not an ethical way to get the Internet to forget things.

Sure there is, be lucky enough to have a common name (or one shared with a celebrity) and wait until enough news piles ontop of your bad news that nobody will ever find it.
https://news.ycombinator.com/newsfaq.html
>"Please do not post job ads as story submissions to HN."

There are automated monthly threads for posting job offers, people looking for jobs, and both freelancing and seeking free lancers.

https://news.ycombinator.com/submitted?id=whoishiring
I'm currently running a Node.js/Express.js/MongoDB service with a Bootstrap/jQuery frontend and iOS + Android clients. My payments mix also tends to be high volume and low margin. I have been extremely satisfied with Stripe - they have a solid api, a great npm package[1] to interface with their api, thorough documentation with examples in node[2], and a wonderful dashboard. I highly recommend them.

1) https://github.com/stripe/stripe-node
2) https://stripe.com/docs/api/node#intro
Oh, you're totally right. I don't work in the mission that often, so i forgot about that.
Got a citation on this? I'd love for it to be true, since it'll save me a lot of effort. But WSJ, for instance, requires you to cancel via phone even if you sign up online.
The critical distinction between the arcade and mobile freemium models is that arcade pricing was skill-based. It's entirely possible to complete Raiden or Street Fighter on a single credit, and indeed the 1-credit-challenge is a convention that keeps a lot of people playing emulated arcade games.

If you tried to "1cc" most mobile games, it would take a fixed amount of time while you wait for your gems or energy or whatever to recharge, and you'd spend most of your time refraining from playing. The two models are certainly on the same evolutionary line, but mobile freemium games are a more blatant and direct psychological hack. The "challenge" is from overcoming your inbuilt desires and delaying gratification - exactly the sort of boring, responsible, real-life stuff people play games to avoid.
You can delete it from your library and it was a pretty honest mistake on their part.

They "purchased" the U2 album on behalf of the users but they clearly forgot that the default was to download that album automatically in the background.
Braintree may have better service but day-to-day stuff (like the UI and how everything generally "works") is much more inferior than Stripe
A tool to "filter" a work of art for yourself is also a tool to censor a work of art for someone else. In this case, and judging by the reactions from some parents here, most likely for your own children. So, despite the interesting framing of this as something that will create the "freedom to filter," it inevitably will be used to oppress.

Regardless, the end effect on the viewers (both willing and unwilling) is that they have not seen the work. They may in fact have a completely different understanding of the film or show than someone who actually has seen the work. A morally ambiguous character becomes wholly righteous. A villain becomes the hero. Violent acts cease to have a consequence of gore, perhaps of pain or death. Romance no longer leads to sex. Dialogue cut for swearing completely changes the perception of a character, the story, and the world.

In the end you have seen something worse than nothing at all--a cartoon caricature of what the creators intended. You have wasted your own time, perverted the aims of the artists behind the work, and done your children a disservice.
Surveillance Oversight Should Be President-Proof, but We’re Still a Long Way Off
What it needs is a parent.
Well, humanity has both trolls and racists.
I switched to Braintree after having some trouble with the initial integration of Stripe in a Rails application I made about 9 months ago. I am an experienced Rails developer and found the Stripe documentation to be a bit out of step with "the Rails way" and a little incomplete. I switched to Braintree and was up and running with relative ease.

I can't speak to my experience as a Braintree customer as sadly my app hasn't processed many payments but the initial integration using Braintree was much easier for me.
Can you elaborate a little more about what kind of texts you were reading from video? Also, how you used the swt for detecting texts/boundaries?
Sure, because we obviously can't make logical conclusions of consequences from actions regarding the issue at hand.

Once Google starts applying local laws globally, there's no stopping it. Everything even remotely controversial (in someone's opinion) will slowly, but surely, disappear from Google. It may take a while, but it will happen.
Are you counting 401k, or strictly after-tax dollars?
> filter bubbles for themselves and their children

We do that all the time. I don't let my kids watch some content because of their age. I filter their activities (don't let them drive until they're able). I try to filter what they eat (less junk food), and their waking hours (try to get them to go to bed). This is no different. It's all cost/benefit, and if some people think some content of any sort is not appropriate for them and their families, fine. But why not allow them the 95% of the content that they like? What if Netflix said you only got to watch a series if you guaranteed you'd watch every episode? The idea is preposterous.
> Privacy is PCI-DSS compliant. We are held to the same rigorous security standards as your bank.

I always giggle when I see that.
>Privacy.com co-founder here

Tell me about AVS please.

Existing virtual card services have me covered on the virtual card front - both cost and (limited) privacy. I want something that gets me past the virtual card + AVS issue. All the virtual card providers seem to suck on this front...
It's "Buddhist" to prioritze people over products?